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1 ocus on oncology (76% of research and 88% of clinical applications).
2 ort half-life of (11)C limits its widespread clinical application.
3 screpancy between research knowledge and its clinical application.
4 O-peptide-based SPR chip detection method in clinical application.
5 ntly, in a model mimicking conditions of its clinical application.
6 ium, none of these have been successful in a clinical application.
7 s, but low oral bioavailability limits their clinical application.
8   Further study is warranted to validate its clinical application.
9 g platform for CTCs detection with potential clinical application.
10 to remove components potentially harmful for clinical application.
11 trol the immune system to enable large-scale clinical application.
12 regnancy is a promising technique for future clinical application.
13 man samples, providing a clear candidate for clinical application.
14 evelopment of in vitro-derived platelets for clinical application.
15 sitates efficacy and safety testing prior to clinical application.
16 adventitial drug delivery system has reached clinical application.
17 wever, prognostic genes have not yet entered clinical application.
18  and chronic graft rejection, limit its wide clinical application.
19 novel biomarker for the diagnosis of TPE for clinical application.
20 side toxicity will likely prevent widespread clinical application.
21  for precision medicine and the obstacles to clinical application.
22 ng their biologic effects has hampered their clinical application.
23 se findings may be readily translated into a clinical application.
24 icardium (BP) extracellular matrix (ECM) for clinical application.
25 s-based nucleases) raise prospects for their clinical application.
26  streamline test interpretation and increase clinical application.
27 gical role of Cif and have the potential for clinical application.
28 SC and provide additional assurance to their clinical application.
29 cell therapies that can be customized to any clinical application.
30 nts affords a framework for potential future clinical application.
31 basophil activation testing being closest to clinical application.
32 ty for basic research, disease modeling, and clinical application.
33 0 and suitable for immunological studies and clinical application.
34 an PSCs remain the bottleneck for successful clinical application.
35 patient cohorts and hence are not useful for clinical application.
36 utic approach with p38 inhibitors for future clinical application.
37 cines have been successfully translated into clinical application.
38 in nephrology from non-targeted discovery to clinical application.
39 ci in hypo-vascularized lesions has hampered clinical application.
40 nclear which strategy is most attractive for clinical application.
41 oth the prognosis and diagnosis of cancer in clinical application.
42 ive from the perspective of potential future clinical application.
43 ular therapy approach and thus adaptable for clinical application.
44 onths, important features for commercial and clinical application.
45  medical stainless steel and polymer for the clinical application.
46 stemic administration of IL-12 precludes its clinical application.
47 he early diagnosis of adverse drug events in clinical application.
48 ffects, bringing this editing tool closer to clinical application.
49 and we suggest has the potential for broader clinical application.
50 ding to potential serious adverse effects in clinical application.
51 ntation of GTD, which will further widen its clinical application.
52 to validate genome editing strategies before clinical application.
53  agents have been successfully translated to clinical applications.
54 ns in nucleic acid sequences is important in clinical applications.
55 ial to transform the role of neuroimaging in clinical applications.
56 delivery systems, which have limitations for clinical applications.
57  allowing for the discovery of more specific clinical applications.
58 nes and nanoprobes and translating them into clinical applications.
59 fate with the degree of precision needed for clinical applications.
60 mpact in fundamental biomedical research and clinical applications.
61 e vision intended for both basic science and clinical applications.
62 d be targeted to harness neuroplasticity for clinical applications.
63 fundamental to optogenetics for research and clinical applications.
64 rapeutic lead for potential translation into clinical applications.
65 es only a small fraction can be explored for clinical applications.
66 c displays of variation, a critical view for clinical applications.
67 n preclinical studies with the potential for clinical applications.
68 slation of new biological understanding into clinical applications.
69  vaccines and has excellent safety record in clinical applications.
70 udies examining CTC clusters in research and clinical applications.
71  of origin, which constitutes an obstacle to clinical applications.
72 ich makes the sensor usable for nonintrusive clinical applications.
73 ore increase their therapeutic potential for clinical applications.
74 le)ruthenate(III)]), which is on the edge to clinical applications.
75 anscription, but is considered too toxic for clinical applications.
76 enging experimentally and even impossible in clinical applications.
77 FGS has great potential for a broad range of clinical applications.
78 fect of integrin antibodies and their use in clinical applications.
79 al to become a powerful tool in terms of its clinical applications.
80 conceptual approaches, scientific tools, and clinical applications.
81 elet forces are desired in both research and clinical applications.
82 ity and limited costs have both research and clinical applications.
83 spensable tool for many biotechnological and clinical applications.
84 ophages are implicated and has potential for clinical applications.
85 of speech imagery neural representations for clinical applications.
86 transient mobilization agents with promising clinical applications.
87 s and how to best take advantage of them for clinical applications.
88 hological neovascularization with a range of clinical applications.
89 ch pathway and has attracting potentials for clinical applications.
90 le and cell isolations for both research and clinical applications.
91 microbial photodynamic inactivation (PDI) in clinical applications.
92 as therefore gained significant interest for clinical applications.
93 ormulations turned out to be inapplicable to clinical applications.
94 e the metabolic status of iPSCs destined for clinical applications.
95 mpact in translating stem cell research into clinical applications.
96 highlights a way to select optimal iPSCs for clinical applications.
97  for decades, and provide guidance for their clinical applications.
98 ing lung inflammation, and discuss potential clinical applications.
99 enic differentiation available for potential clinical applications.
100 ules, and hold great promise for medical and clinical applications.
101 ing fundamental biology as well as potential clinical applications.
102 ak to be sutured or conveniently handled for clinical applications.
103  clusters resulting in 6 clusters for future clinical applications.
104 population is desired in many biomedical and clinical applications.
105 uences for use in translational research and clinical applications.
106  biomedical research and holds potential for clinical applications.
107  brain and provide essential information for clinical applications.
108 retinal prosthetics, paving the way to novel clinical applications.
109 piate respiratory depression, which may have clinical applications.
110 lustrate how modeling can be translatable to clinical applications.
111 ces, including paper and polymers, and their clinical applications.
112 heir potential impact on future research and clinical applications.
113  vital for progressing such a system towards clinical applications.
114 inflammatory disease, and a novel target for clinical applications.
115 ncer in both pre-clinical animal studies and clinical applications.
116 ct-ratio, providing a promising solution for clinical applications.
117  research, drug development, and potentially clinical applications.
118 etative accuracy and understanding potential clinical applications.
119  and its potential as a new target in MM for clinical applications.
120 se undesirable side effects that limit their clinical applications.
121  to manipulate primitive features in HSC for clinical applications.
122 studying its function and may have potential clinical applications.
123            It is suitable for both basic and clinical applications.
124 ctive for differential diagnosis in concrete clinical applications.
125  have led to new discoveries with remarkable clinical applications.
126 c substrate, both as a research tool and for clinical applications.
127 ization of 2A peptides in basic research and clinical applications.
128 concentrations, showing promise for eventual clinical applications.
129 in vivo studies on animals and ultimately to clinical applications.
130 or means of translating biological data into clinical applications.
131  high impact in basic research as well as in clinical applications.
132 ithin this landscape may provide insights to clinical applications.
133 es in bone tissue engineering with numerable clinical applications.
134 fabricated in monolithic form for a range of clinical applications.
135 vated, culled, and manicured toward intended clinical applications.
136 /-17%, permitting its use in preclinical and clinical applications.
137 disease associations and translate them into clinical applications.
138 potential of the biosensor for point-of-care clinical applications.
139 active cannabinoid compounds, and could have clinical applications.
140 ns should be considered in both research and clinical applications.
141 chnologies have the potential to enhance its clinical applications.
142 idated strategies for developing theranostic clinical applications against Alzheimer's disease.
143  high sensitivity, showing great promise for clinical application and biomedical diagnosis.
144 mpetent targeting property largely limit its clinical application and efficiency.
145 ene biosensors provide an effective tool for clinical application and point-of-care medical diagnosti
146 h sensitivity and it holds great promise for clinical application and provides a new platform for imm
147 es is a significant concern for their use in clinical applications and disease modeling.
148 herefore may have further potential in other clinical applications and drug-screening studies.
149  and other diseases, and discusses potential clinical applications and the possible future clinical u
150 s drawn from metagenomic data is crucial for clinical applications and to prevent incorrect biologica
151 nces in both approaches, with an emphasis on clinical applications, and highlight the utility of comb
152 uivalents have been successfully deployed in clinical applications, and skin epidermal stem/progenito
153 atient, makes it particularly well suited to clinical applications, and we argue the potential of thi
154                 Critical limitations to Treg clinical application are the paucity of cells and limite
155 torial approach could be highly effective in clinical application as it allows for cooperative and co
156 ighlights the MAR assay in both research and clinical applications as a promising tool for predicting
157 er, the full L1 sequence is not suitable for clinical applications, as each protein domain may contri
158 nsitive detection approaches used in current clinical applications, but always face a performance tra
159 g sequences have important basic science and clinical applications, but they are often confounded by
160  existing preclinical single-port system for clinical application by integrating the sensors of a pho
161 dology and might bring the potential for its clinical application closer.
162                                              Clinical Application: Compared with D1 lymphadenectomy (
163 to the region of interest will vary for each clinical application considered.
164 egrated in the treatment planning system for clinical application directly.
165 it suitable for sample analysis in a typical clinical application environment.
166       Collectively, these findings provide a clinical application for AZD1775 with DNA-damaging agent
167 ant improvements are required to enhance its clinical application for delivery of large sized therape
168 rted the validity of the proposed system for clinical application for the detection of multiple analy
169     These results have potentially important clinical applications for disorders associated with redu
170 unoregulatory function of D-mannose may have clinical applications for immunopathology.
171 pathogen discovery, discuss improvements and clinical applications for the detection of microbially a
172 quently, PRP could have relevant oncological clinical applications for the treatment of advanced or m
173 , paraffin-embedded tumor tissue, supporting clinical applications for this methodology.
174 stasis and might be a useful tool for future clinical applications, for example, response assessment.
175 utical with a growing repertoire of putative clinical applications from hypovolemia to Alzheimer's di
176 a promising therapy for type 1 diabetes, its clinical application has been hampered by cellular rejec
177 slation from neurodevelopmental discovery to clinical application has transformative potential for ps
178 growing number of delivery approaches toward clinical applications have been developed, including nan
179 challenging clinical problem that limits its clinical application in pain treatment.
180 ifficulty, limiting the possibility of wider clinical application in patients.
181           The feasibility of this method for clinical application in point-of-care technology is eval
182 cute and chronic renal injuries and may have clinical application in protection from ischemic-induced
183 dels, and functional assessment, may improve clinical application in regenerative medicine.
184 iated malignancies and suggest its potential clinical application in the identification of Myc-driven
185 ed by nuclear RA receptors (RARs) limits its clinical application in treating cancer.
186 ne-mediated neuroinflammation with potential clinical applications in a wide range of inflammatory di
187  Therefore, topical BRAF inhibitors may have clinical applications in accelerating the healing of ski
188 e promoting allograft survival that may have clinical applications in alloimmunity and in a wide spec
189 cts of CD39 on T cells and explore potential clinical applications in autoimmunity, chronic infection
190 f each modeling approach and their value for clinical applications in diagnosis, therapy, and prevent
191                                         With clinical applications in mind we compare results from al
192                                The potential clinical applications in mixed cell differentiation carc
193 ividualized anthropomorphic phantoms in many clinical applications in nuclear medicine.
194 As are likely to serve as the basis for many clinical applications in oncology.
195 ies, providing a flexible tool for potential clinical applications in precision medicine.
196 utoregulation, measurement methodologies and clinical applications in stroke to help build a consensu
197  potentials for both laboratory research and clinical applications in the aging population.
198 line (ACh) receptors (nAChRs) have potential clinical applications in the treatment of nicotine depen
199                                    Potential clinical applications include assessment of the HER2 sta
200 swab analysis by DESI-MS for a wide range of clinical applications including rapid mucosal diagnostic
201 hip is also commercially promising for other clinical applications, including 3D cell culture and mic
202 owever, much remains to be considered before clinical applications, including the reproducibility of
203 ward for research, ethics, and governance of clinical applications involving genome editing.
204 zyme is useful both in basic research and in clinical applications involving this pathway, but curren
205                                However, E2's clinical application is less appreciated due to several
206                                              Clinical application is limited by low levels of donor c
207                   However, a less well-known clinical application is the therapeutic use of low-dose
208                                        Their clinical application is undisputed in acute (e.g., posto
209 alth of investigated new research topics and clinical applications is further discussed, including im
210  This wide gap between bench discoveries and clinical applications is mainly because of our limited u
211          Moving towards the eventual goal of clinical application it is necessary to develop new meth
212                                   Before its clinical application, it is particularly important that
213                                              Clinical Application: Local cervical treatment does not
214 state of the technology, with a focus on the clinical applications made possible by these agents.
215 ale studies offering strong support for this clinical application, more recent larger-scale studies h
216                                          For clinical applications, nanobodies (VHH) derived from hea
217 the sodium-iodine symporter and describe the clinical application of (124)I dosimetry in a patient wh
218 ive research, with notable exceptions, broad clinical application of ADC remains elusive; major hurdl
219  Finally, we provide insights into potential clinical application of adenosinergic and other purinerg
220             Appropriate use criteria for the clinical application of amyloid imaging are established,
221                               However, broad clinical application of BAT demands further standardizat
222                                 However, the clinical application of BChE is limited by two obstacles
223               To highlight the potential for clinical application of biomarkers, the most pertinent b
224 g and packing density when investigating the clinical application of bone cements for infection manag
225           Coincident with rapid expansion in clinical application of cancer immunotherapies, here we
226          The benefits and feasibility of the clinical application of cell-based therapy has been demo
227                We also discuss the potential clinical application of chemical inhibitors of antibioti
228 e approval for treatment of various cancers, clinical application of cytokines is still impeded by th
229 ccuracy and practicality limit the immediate clinical application of each method.
230 are warranted to define the most appropriate clinical application of eGFRcys and eGFRcreat-cys.
231                      Given the challenges of clinical application of functional assays, we argue that
232 ative conditioning is relevant for a broader clinical application of gene therapy.
233                                   (3) Future clinical application of human germline genome editing sh
234                                The potential clinical application of IgE-derived drugs in clinical on
235                                              Clinical application of immunotherapeutic approaches has
236 drugs is considered a major obstacle for the clinical application of inhaled chemotherapy.
237 vidual centers, primarily because of unequal clinical application of knowledge gained from research.
238                     For establishment of the clinical application of metabolic treatment response stu
239 d sensitize cells to etoposide, suggesting a clinical application of miRNAs as therapeutics to target
240 e UK became the first country permitting the clinical application of mitochondrial replacement techni
241 he potential of this imaging technology, the clinical application of MRI in the care of PSC patients
242                          We describe a novel clinical application of OCTA in a patient with dural car
243 g islet transplantation and importantly, the clinical application of personalized beta-cell replaceme
244                                     However, clinical application of phototriggerable systems have be
245 ses on the highlights of the development and clinical application of PSMA ligands.
246 initive conclusion can be achieved about the clinical application of such a treatment option.
247 h FET devices demonstrates the potential for clinical application of synthetic hybrid receptors for t
248                                          The clinical application of T cell immunotherapy depends on
249                           To investigate the clinical application of targeting JAK for ALK- ALCL, we
250 utline the mechanism of activity and current clinical application of temozolomide, which, until now,
251 e GG assay has the potential to increase the clinical application of the GGI, but robust demonstratio
252                To provide guidelines for the clinical application of the Standards for Dermatological
253 uss the preclinical work that has led to the clinical application of the various approaches and a sum
254 ogenous retroviruses (PERVs) has impeded the clinical application of this approach.
255                                      Towards clinical application of this platform, nanotubes were ev
256                                     However, clinical application of this technique is complex and di
257                                              Clinical application of umbilical cord blood (UCB) as a
258 This article presents current and developing clinical applications of cardiac T1 mapping and reviews
259  this series puts particular emphasis on the clinical applications of EVs as therapeutics and as diag
260 re has been a growing interest regarding the clinical applications of exosomes and their role in prog
261 ed brain-targeting by ANG favours the future clinical applications of f-MWNT-ANG to deliver active th
262 o facilitate research on the possible future clinical applications of gene editing.
263  multidimensional level will greatly benefit clinical applications of genomic information in diagnosi
264 se the recent progress of the most important clinical applications of HSA-binding platforms, and spec
265                                              Clinical applications of induced pluripotent stem cells
266                          With a focus on the clinical applications of lung cancer screening and lung
267            These results encourage potential clinical applications of M-CSF to prevent severe infecti
268 the study of brain disease, and, ultimately, clinical applications of neuroimaging.
269                 However, the most widespread clinical applications of SIT require a long period of do
270    The biological significance and potential clinical applications of the mirror code are discussed.
271 ation, followed by a discussion of potential clinical applications of this technique for the detectio
272  opportunities for immunotherapy, as well as clinical applications of various types of therapeutic nu
273 study provides a new understanding of DHI in clinical application on cardiovascular and cerebrovascul
274                       For a demonstration of clinical applications, paper-based Cl(-) and K(+) sensor
275                                              Clinical Application: Patients with EGFR-mutant or ALK-p
276 ource for cancer investigation and potential clinical application related to miRNAs.
277 traordinary potential in bone formation, its clinical applications require supraphysiological milligr
278         However, their full translation into clinical application requires efficient delivery strateg
279                                           In clinical application, severe xerostomia became the dose-
280 rently and urgently needs to be improved for clinical applications such as angiography and brain perf
281 se the promise of translational research via clinical applications such as drug development and patie
282         These findings have implications for clinical applications such as non-invasive brain stimula
283 ecific CTC readout, enabling high-throughput clinical applications, such as noninvasive screening for
284                                   This first clinical application suggests that controlled graft rewa
285 on processes are critical considerations for clinical application that should be considered when deve
286 OMIS domain scores in research studies or in clinical applications that measure and evaluate the symp
287     As an encouraging feature for envisioned clinical application, the IC50 of MEAN was not significa
288 d disease; and subsequently focus on its key clinical applications, the detection and localization of
289 esearch, diagnostics and separations and for clinical applications, the most common of which are anti
290 s, however, are permanent and are limited in clinical application to indolent malignancies of low- to
291          EGFRt can be incorporated into many clinical applications to regulate the survival of gene-e
292 int-of-care testing has been translated into clinical applications to support a prompt decision on pa
293                                              Clinical application was performed with analysis of the
294                                              Clinical application was performed with analysis of the
295                                          For clinical application, we developed a high-throughput mas
296                  These have led to potential clinical applications; we identify challenges to their t
297 nd pseudocontinuous ASL, as well as emerging clinical applications will be reviewed.
298 r biomarkers spermine and spermidine in real clinical applications with reduced sample preparations.
299 olic and molecular imaging clinical and near-clinical applications within atherosclerosis and venous
300 -of-care (POC) platform for low target count clinical applications without the need for amplification

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