ライフサイエンスコーパス: clinical course

1 but have also been deployed to forecast the clinical course.

2 n hospital are at increased risk of a severe clinical course.

3 rvision due to the possibility of the severe clinical course.

4 changes in work productivity and longer-term clinical course.

5 sma cell neoplasm with an extremely variable clinical course.

6 ammatory lesions and shows a more aggressive clinical course.

7 bsequent pars plana vitrectomy for worsening clinical course.

8 uld guide novel interventions to improve its clinical course.

9 f rotating call schedules; and 3) changes in clinical course.

10 tions of different inflammation markers, and clinical course.

11 ate their relationship with the etiology and clinical course.

12 nt subtype, gait freezing, and an aggressive clinical course.

13 ontrast to a previously stable, asymptomatic clinical course.

14 ignificant heterogeneity of AP causation and clinical course.

15 as a candidate responsible for an aggressive clinical course.

16 d measurement of disease activity during the clinical course.

17 type distribution differed significantly by clinical course.

18 itably fatal disorder, has a highly variable clinical course.

19 ith atypical radiology and a more aggressive clinical course.

20 ly lethal cancer known for its unpredictable clinical course.

21 mature B cells but also its highly variable clinical course.

22 ents, respectively, at least once during the clinical course.

23 the in vitro T cell defects and improved the clinical course.

24 nce; all presented a chronic, long-surviving clinical course.

25 ll neoplasm characterized by rather indolent clinical course.

26 oot or arch repair leads to a highly complex clinical course.

27 ous manifestations and a rapidly progressive clinical course.

28 r failure of medical management early in the clinical course.

29 MT neuropathy score gradient to evaluate the clinical course.

30 d and reported blind to patient identity and clinical course.

31 ents through the entire disease spectrum and clinical course.

32 ready at early disease stages and impact the clinical course.

33 imes EMB provided a diagnosis or altered the clinical course.

34 sis history, who might exhibit a more severe clinical course.

35 a subset of patients may follow an indolent clinical course.

36 stage at presentation, and a more aggressive clinical course.

37 kine production and were correlated with the clinical course.

38 end point that evaluated the initial 48-hour clinical course.

39 epilepsy in such patients may improve their clinical course.

40 ncer treatment, and most had an unremarkable clinical course.

41 LBP are musculoskeletal and benign in their clinical course.

42 al subtype, with later onset and less severe clinical course.

43 T and TT genotype and the severity of the AP clinical course.

44 thin the CSF produced C3 in correlation with clinical course.

45 37.5%, and 2 persons had a severe disabling clinical course.

46 ciated with a heterogeneous presentation and clinical course.

47 ic/myeloproliferative neoplasm with variable clinical course.

48 , brain oxygenation), structural injury, and clinical course added less.

49 study is to describe disease recurrence and clinical course after LT.

50 Disease duration, clinical course, age, and gender contribute to the dynam

51 with IVIG, which is related to a more severe clinical course and a poorer outcome.

52 They are characterized by differences in clinical course and by divergent addiction to oncogenic

53 ns and malignant lymphoma may complicate its clinical course and contribute to its poor prognosis.

54 thal malignancy notorious for its aggressive clinical course and eventual resistance to existing ther

55 l mutations and is characterized by indolent clinical course and favorable outcome.

56 racterized by an initial relapsing-remitting clinical course and focal inflammatory lesions that have

57 ollowed to 90 days after initial imaging for clinical course and for the primary outcome of any inter

58 ene and immunoglobulin locus, has a variable clinical course and frequently undergoes transformation

59 pe A receptor antibodies associated with the clinical course and histopathological findings of intest

60 Clinical course and histopathology of a patient diagnose

61 homa (MCL) is characterized by an aggressive clinical course and inevitable development of refractory

62 There is limited information regarding the clinical course and management of FAT.

63 Detailed clinical data are limited on the clinical course and management of patients with EVD outs

64 and ophthalmic diagnostic tests, as well as clinical course and management, were determined.

65 HE1 gene transfer dramatically improved both clinical course and metabolic abnormalities.

66 ma CRVO group to elucidate the demographics, clinical course and ocular parameters of these two cohor

67 n addition, the extreme heterogeneity of the clinical course and our improved ability to foresee the

68 Clinical course and outcome data were collated prospecti

69 However, the influence of AF on clinical course and outcome in HCM remains incompletely

70 iomarker of health and inflammation, and the clinical course and outcome of GBS in patients treated w

71 ited States with the objective to define the clinical course and outcomes in transfusion-related acut

72 e latter, however, have different effects on clinical course and outcomes.

73 e affected blood vessels correlates with the clinical course and prognosis in patients with vasculiti

74 The authors aimed to clarify clinical course and prognosis of a large cohort of HCM p

75 e in peripheral blood eosinophils during the clinical course and received prednisolone for the same,

76 eyes (19.4%), and on the basis of a typical clinical course and response to treatment in 37 eyes (18

77 contribute to their relatively more indolent clinical course and responsiveness to therapy.

78 /S) classification of GBM tumors can predict clinical course and sensitivity to drug treatment.

79 We studied the clinical course and sequelae of CGD patients diagnosed b

80 We assessed the clinical course and the fulfillment of current treatment

81 Given differences in clinical course and therapy response, we sought to chara

82 n of subgroups is important in understanding clinical course and to anticipate resuscitative and ther

83 his could have implications to predict later clinical course and to select appropriate management app

84 nd included all studies that reported on the clinical course and treatment for foodborne botulism.

85 se, no BM investigation is required, but the clinical course and tryptase levels are monitored in the

86 We describe the clinical course and virological characteristics of the f

87 representing the major phases of the glioma clinical course and were further subgrouped by histology

88 vations: In this case series, we explore the clinical courses and genotypes of a woman and her 2 daug

89 ide variants and is associated with distinct clinical courses and response to therapy.

90 The patients' clinical courses and responses to treatment over a follo

91 his study, we have examined and reported the clinical courses and symptoms of our cases.

92 Such patients often have complicated clinical courses and ultimately die of infection and sep

93 egarding the minimum exposure, nature of the clinical course, and additional clinical features needed

94 What is changing is our definition(s), its clinical course, and how we manage the septic patient.

95 ecrease of TBRs was associated with a stable clinical course, and in 2 patients PET detected residual

96 often hallmarks cases with a more aggressive clinical course, and large tumor cells may express CD30.

97 Visual acuity, clinical course, and multimodal imaging study results.

98 reus, heterogeneity of disease presentation, clinical course, and outcome between individual S. aureu

99 The findings on presentation, clinical course, and outcome of a series of 7 eyes of 4

100 The demographics, clinical features, clinical course, and outcomes of the 6 patients with RVP

101 wledge of the genetic and molecular origins, clinical course, and outcomes of the most common phenoty

102 ecorded postoperative VA, time to NLP onset, clinical course, and principal cause.

103 ent demographic characteristics, treatments, clinical course, and serologic and genetic markers.

104 ty of approaches to diagnosis, a spectrum of clinical courses, and unsettled perspectives on therapeu

105 elop skin lesions, but the lesions and their clinical course are not well-characterized.

106 acteristic curve analyses using histology or clinical course as a reference.

107 worldwide, we found significant variation in clinical course associated with age at diagnosis, sex, a

108 ution from 2000 to 2012 and investigated the clinical courses associated with distinct MAC species.

109 ase appear to experience a relatively benign clinical course, associated with a low risk for advanced

110 arance (dense deposit disease and C3 GN), or clinical course (atypical postinfectious GN).

111 The disease can have divers clinical course but usually manifests as oligoarthritis.

112 ence of EAE or the trajectory of its initial clinical course, but it limited the extent of chronic CN

113 Clinical course, cerebrospinal fluid (CSF)-, MRI studies

114 ssion of CD20, plasmablastic morphology, and clinical course characterized by early relapses and subs

115 To describe the phenotype, long-term clinical course, clinical variability, and genotype of p

116 e seasonal influenza and the more protracted clinical course compared with that of H5N1 suggests that

117 igh-risk neuroblastomas have an unfavourable clinical course despite intensive multimodal treatment,

118 ropsychological factors robustly explain the clinical course, directing our focus to the brain.

119 ct had an early-onset but slowly progressive clinical course dominated by neurological deterioration

120 turbidimetry and related to demographics and clinical course during a follow-up of 6 months.

121 elapsing-remitting MS patients changed their clinical course during the study and entered into the se

122 The clinical course, electrocardiograms, and Holter monitori

123 Heterogeneity in the clinical course ensures predicting metastasis is notorio

124 he role of the innate immune response in the clinical course following severe injury and envisions a

125 onal diagnostic screening information in the clinical course for patients suspected of having an AMI.

126 2015, to provide individual patient data on clinical course from CCM diagnosis until first CCM treat

127 has been postulated to lead to a more severe clinical course from other structurally related viruses,

128 enesis, surgical concerns, and postoperative clinical course from those of age-related cataracts, and

129 The clinical course has not been described previously.

130 y mass index (BMI) on cardiac phenotypic and clinical course in a multicenter hypertrophic cardiomyop

131 These observations correlate with a severe clinical course in DC-specific MK2 knockout mice compare

132 unique aspects of P. malariae diagnosis and clinical course in travelers.

133 tion in genes previously associated with CLL clinical course, including TP53 (27.5%), NOTCH1 (24.1%),

134 Erosion of LAGB is uncommon and its clinical course is benign.

135 on in DLBCL is associated with an aggressive clinical course, is more common in the ABC subtype, and

136 gressive tumour in both species with a rapid clinical course leading ultimately to metastasis.

137 of JAK2, CALR, (calreticulin gene) or MPL on clinical course, leukemic transformation, and survival o

138 which may reverse across development or the clinical course; maladaptive rumination and poor executi

139 ase in the number of CTCs during a patient's clinical course may be a harbinger of forthcoming overt

140 l to assess their impact on the longitudinal clinical course (measured by means of Expanded Disabilit

141 Clinical course, muscle and nerve morphology, longitudin

142 D prevention, have significantly altered the clinical course, now resulting in a low disease-related

143 We determined the clinical course of 301 consecutive patients with ARVC us

144 We analyzed the clinical course of 34 AML+13 patients enrolled in the Ge

145 Prompted by the clinical course of a renal allograft recipient, who lost

146 The clinical course of acute infections required suppressive

147 78) CTRC and the incidence together with the clinical course of acute pancreatitis (AP).

148 oxicity in the surrounding neuropil over the clinical course of AD, thereby potentially contributing

149 burden remains relatively stable through the clinical course of AD, whether these features of local p

150 the cortico-cerebellar processes tied to the clinical course of ADHD are separated from the subcortic

151 have significantly improved survival and the clinical course of adult HCM patients.

152 To describe the clinical course of advanced juxtapapillary retinal capil

153 ariants in the complement pathway modify the clinical course of AMD and increase the risk of developi

154 This study sought to describe the clinical course of ARVC and occurrence of life-threateni

155 and conflicting data regarding the long-term clinical course of atopic dermatitis (AD).

156 rt, to our knowledge for the first time, the clinical course of atopic dermatitis in an unselected co

157 ebral cortical anatomy have been tied to the clinical course of attention deficit hyperactivity disor

158 The clinical course of autoimmune and infectious disease var

159 es, and strains within a serotype affect the clinical course of bluetongue.

160 r understanding of the burden AKI has on the clinical course of burn patients would highlight the nee

161 ogenesis and endotypes and prediction of the clinical course of childhood asthma phenotypes.

162 at lymphocyte trafficking contributes to the clinical course of chronic lymphocytic leukemia (CLL), b

163 BACKGROUND & AIMS: The clinical course of chronic pancreatitis is unpredictable

164 The heterogeneous clinical course of CLL is likely explained by underlying

165 drives the development and can influence the clinical course of CLL.

166 The clinical course of complications was highly variable, fr

167 f exosomes are associated with the onset and clinical course of critical illness.

168 unusual histologic presentation and distinct clinical course of dense deposit disease, discuss the pi

169 oprotein (MOG)-induced EAE would improve the clinical course of disease relative to artificial CSF (A

170 gG in STAT3-HIES patients and attenuated the clinical course of disease suggesting a role of humoral

171 ritoneally with Brucella melitensis, and the clinical course of disease, histopathologic changes, and

172 BcR-BcR interactions apparently dictate the clinical course of disease, with stronger affinities and

173 th Carolina to describe the epidemiology and clinical course of disease.

174 The clinical course of EAE is not improved by the solTNF inh

175 that both cibinetide and EPO ameliorated the clinical course of experimental colitis in mice, resulti

176 ne the incidence rate, principal causes, and clinical course of eyes developing no light perception (

177 This report reviews the clinical course of FMD involving the coronary arteries a

178 gressive lymphoma is a critical event in the clinical course of follicular lymphoma (FL) patients.

179 We describe the clinical course of four patients who had Trichosporon my

180 To determine the epidemiology and clinical course of functional impairment and decline in

181 Ripk3 deficiency substantially improved the clinical course of GD mice, with increased survival and

182 tations in humans, potentially modifying the clinical course of genetic diseases, remains unknown.

183 To analyze the incidence and clinical course of graft rejection episodes after Descem

184 contribute to HCL pathogenesis or affect the clinical course of HCL are currently not described.

185 hypertrophy is an early hallmark during the clinical course of heart failure and is regulated by var

186 association between Vitamin D levels and the clinical course of HL needs to be collected to advance t

187 recovered after parturition, resembling the clinical course of ICP in human.

188 The clinical course of idiopathic pulmonary fibrosis (IPF) i

189 The clinical course of idiopathic pulmonary fibrosis and non

190 r myeloid cell compartment had a more severe clinical course of infection and increased parasite burd

191 ce in northern Germany and characterized the clinical course of infection and viral tissue tropism to

192 Representative information on clinical course of invasive meningococcal disease (IMD)

193 The clinical course of low back pain is often favourable, th

194 Because the clinical course of low-grade gliomas in the individual a

195 Data on the clinical course of lupus anticoagulant (LA)-positive ind

196 We ascertained the clinical course of maculopathy in paraproteinemia and in

197 rge animal studies to most closely mimic the clinical course of MI and enable translational success.

198 nd model experimental design to resemble the clinical course of MI.

199 ccumulation in the blood and ameliorated the clinical course of mice that were injected with myelin-r

200 y a pivotal role in determining the changing clinical course of MS.

201 maging parameters predictive of the changing clinical course of multiple sclerosis (MS) from relapsin

202 The clinical course of multiple sclerosis is variable, and t

203 giography may help the clinician predict the clinical course of neovascular AMD subjects undergoing i

204 We describe the early clinical course of outbreak-associated infections.

205 Given that the clinical course of oxaliplatin-induced neuropathy is not

206 The clinical course of P0106-125-induced EAN in mice deficie

207 ranscription pathway in the pathogenesis and clinical course of pancreatic cancer.

208 ess these limitations; it aims to assess the clinical course of patients as a physician would in prac

209 healthy individuals and also complicates the clinical course of patients requiring intensive care as

210 ly one of the rare avenues for improving the clinical course of patients undergoing pancreatic surger

211 facilitating decongestion and improving the clinical course of patients with acute heart failure (AH

212 RCA2a at the dose tested did not improve the clinical course of patients with heart failure and reduc

213 The clinical course of patients with hypertrophic cardiomyop

214 herapeutically [therST]) on the longitudinal clinical course of patients with natalizumab-related pro

215 -cell transplantation (SCT), we compared the clinical course of patients with NPM1(mut) AML eligible

216 s study sought to describe the frequency and clinical course of patients with surgically removed PFE

217 The majority of available data on the clinical course of patients with ventricular preexcitati

218 Findings demonstrate that although the clinical course of PTSD symptoms shows heterogeneous pat

219 The clinical course of PTSD varies between individuals, and

220 The clinical course of RCVS is traditionally considered mono

221 t B cells play a vital role in mediating the clinical course of relapsing multiple sclerosis (MS).

222 According to previous studies, the clinical course of sepsis could be affected by preexisti

223 The clinical course of septic arthritis and histopathologica

224 emoglobin (HbF) is the major modifier of the clinical course of sickle cell anemia.

225 The clinical course of spontaneous HBsAg seroconversion was

226 is presented due to the relapsing-remitting clinical course of the disease that resulted in patient'

227 xplore the effects of these mutations on the clinical course of the disease.

228 represent a new window for prediction of the clinical course of the disease.

229 sk factors and (2) immune markers across the clinical course of the disorder, including cytokines; C-

230 enograft model, consistent with the indolent clinical course of the human SOX11-negative mantle cell

231 their abundance seems to correlate with the clinical course of the infection.

232 The protracted clinical course of the MPNs has limited the use of poten

233 The clinical course of the patients was similar to that of p

234 r, little is known about the epidemiology or clinical course of these problems, including the extent

235 The findings suggest that the clinical course of this common childhood onset disorder

236 offer an explanation of the acute-on-chronic clinical course of this common mitochondrial encephalopa

237 Clinical course of this disease remains poorly understoo

238 The clinical course of those infected with ON1 was comparabl

239 tablished in recipient mice, we mimicked the clinical course of treatment by conducting a mastectomy.

240 We assessed clinical courses of 388 patients who had ACLF at enrollm

241 cterial intrahost evolution, we examined the clinical courses of 4 subjects with 3-6 recurrent USA300

242 The heterogeneous clinical courses of chronic hepatitis B virus (HBV) infe

243 cal record review compared epidemiologic and clinical courses of pertactin-producing and pertactin-de

244 Little is known about the clinical course or predictive variables.

245 inct recovery phenotypes on the basis of the clinical course over the first week after AKI manifestat

246 icantly lower in patients with uncomplicated clinical courses (p < 0.001).

247 nervous system (CNS) manifested with varying clinical course, pathology, and inflammatory patterns.

248 nd clinical factors were evaluated to assess clinical course, patterns of recurrence, and survival ou

249 er, relatively little is known regarding its clinical course post-LT.

250 -level data limit capabilities to understand clinical course, predict outcomes, ensure resource avail

251 Little is known about the clinical course, prognosis and treatment of autoimmune r

252 o recognize in patients due to its impact on clinical course, prognosis, and treatment strategies.

253 nd both approaches add significant value for clinical course prognostication.

254 he radiation emitted by (210)Po, an atypical clinical course prompted active consideration of poisoni

255 rs in patients with immunodeficiency and the clinical course ranges from indolent behavior to that of

256 data suggest that BCOR mutations define the clinical course rather than disease initiation.

257 identified and their injection histories and clinical courses reviewed.

258 time should reflect response to therapy and clinical course, serial measurement of LVEF is inconsist

259 nce of HBV replication was associated with a clinical course similar to that of HCV monoinfected pati

260 isual acuities and treatments throughout the clinical course, specific dimensions of the macular hole

261 inflammatory component and occasional benign clinical course suggest that LCH may not be a neoplasm.

262 (WGD), which was associated with aggressive clinical course, suggesting WGD is a hallmark of disease

263 Females have a more severe clinical course than males in terms of several inflammat

264 mutations and PCH and suggests a less severe clinical course than other PCH subtypes.

265 Outpatients with HFrecEF have a different clinical course than patients with HFpEF and HFrEF, with

266 two CLL subtypes associated with a different clinical course that drew attention.

267 o present with a mass have a more aggressive clinical course that may be fatal, justifying cytotoxic

268 Exposure to (210)Po resulted initially in a clinical course that was indistinguishable from infectio

269 Due to their protracted clinical course, the evolution to advanced hematological

270 However, based on the clinical course, the patient was suspected to have eosin

271 During the clinical course, the predominant findings included diarr

272 challenging surgical procedures and complex clinical courses, the patients benefit from avoidance of

273 ent cancer types, with distinct histologies, clinical courses, therapeutic responses, and genetic dri

274 Most deaths occurred early in the clinical course; therefore, botulism in children should

275 rents may cause human epilepsy with a severe clinical course, thus revealing a previously unexplored

276 gards to the circumstances that drive a mild clinical course to a severe disease.

277 ise and to examine their natural history and clinical course to create a more robust understanding of

278 We present the clinical course, treatment, and prognosis of a case of u

279 urable with conventional therapies and has a clinical course typified by multiple relapses after ther

280 The attenuated clinical course was associated with a relative dearth of

281 Because a favourable clinical course was associated with catch-up growth, hei

282 The patient's clinical course was complicated by cardiopulmonary failu

283 His clinical course was complicated by debilitating neurolog

284 Assessment of the patient's clinical course was defined by the following: an acute e

285 Although the clinical course was favorable in all cases, tenosynoviti

286 attern of photoreceptor dysfunction, but the clinical course was nevertheless slowly progressive.

287 Progressive clinical course was observed in 45%, carotidodynia in 10

288 A dose- and donor-dependent clinical course was observed in hu-BLT mice infected wit

289 fferentiation response gene 88, or TRIF, the clinical course was significantly attenuated compared to

290 The clinical course was slowly progressive.

291 Visual outcomes, causative organisms, and clinical course were also recorded.

292 Changes in access and speed of care and clinical course were determined through 1746 random hous

293 Cases were defined as infants whose clinical courses were consistent with necrotising entero

294 With the exception of one case, patient clinical courses were not consistent with true invasive

295 tic inaccuracy is more frequent early in the clinical course when signs and symptoms are mild.

296 patients suggests that RALD has an indolent clinical course whereas JMML is fatal if left untreated.

297 specific subset generally followed the same clinical course, whereas patients in different stereotyp

298 They had a less severe clinical course with greater event-free survival from ma

299 rences in surface area at baseline predicted clinical course, with individuals that subsequently beca

300 te and relative risk of VTAs and a favorable clinical course within 2.2 years of follow-up.