ライフサイエンスコーパス: clinical dose

1 than that observed in humans at the maximal clinical dose.

2 tion dose to one half and one quarter of the clinical dose.

3 nistrations at 4 times the anticipated human clinical dose.

4 duce immune activation at safe and tolerable clinical doses.

5 and bupivacaine) were added to solutions in clinical doses.

6 ut did not resolve renal injury at practical clinical doses.

7 This report demonstrates that a clinical dose (1 mg/kg/day) of 13-cis-RA in mice signifi

8 sed favorable properties and a predicted low clinical dose (2 mg twice daily).

9 fasted or normally fed mice at the standard clinical dose 30 micromol/kg, both 3,4,3-LI(1,2-HOPO) an

10 heart (n=6) preparations by applying HIFU at clinical doses (4-16 W).

11 y doses of drugs and X-rays to 2-6% of their clinical doses and efficiently spares normal cells.

12 om the haemopoietic properties that occur at clinical doses and which, at the highest doses, might le

13 ting disorders, the drug was administered at clinical doses, both in vivo and in vitro, to rat dorsal

14 wever, the time requirement for synthesis of clinical doses can hinder patient throughput because of

15 coadministration of lapatinib or imatinib at clinical doses could result in a significant increase in

16 At their clinical doses, current antipsychotic agents share the p

17 nd are identical to those used currently for clinical dose estimates for beta-particle emitters.

18 (ADR) and informed predictions about optimal clinical doses, expected performance of standard doses a

19 openic murine pneumonia model with simulated clinical dosing exposures was used to validate our quant

20 tween 1991 and 2006 and classified them into clinical (dose-finding trials) and statistical trials (m

21 y relevant to tumor response during standard clinical dose-fractionated radiation therapy.

22 The standard clinical dosing group received doses individualized to c

23 However, the clinical dose is approximately 250-1000 times lower than

24 Ionizing radiation at clinical dose levels activates both pro- and anti-prolif

25 ed for more than 4 seconds in spiral mode at clinical dose levels.

26 dic reactor capable of synthesizing a single clinical dose of (89)Zr-labeled antibody.

27 oing are highly sensitive to disruption by a clinical dose of 13-cis-RA.

28 The clinical dose of 4-HPR, however, is limited by residual-

29 At one-tenth the current clinical dose of contrast agent, and following a single

30 ays starting after the final dose of CCl(4) (clinical dose of gadoxetate disodium is 0.25 mmol/kg).

31 Treatments with GSK-3 inhibitors including a clinical dose of lithium to rats with thoracic spinal co

32 were also scanned after pretreatment with a clinical dose of the aromatase inhibitor letrozole.

33 ered in SAB synthesis for the preparation of clinical doses of (211)At-labeled radiopharmaceuticals.

34 or appropriate formulations and dilutions of clinical doses of 90Y immunopharmaceuticals immediately

35 tor dial setting for accurate calibration of clinical doses of 90Y preparations.

36 behavioural effects of fetal treatment with clinical doses of betamethasone and dexamethasone; (2) d

37 These results predict that clinical doses of bupivacaine would decrease the peak an

38 enfluramine (DF) in human subjects receiving clinical doses of DF and to determine whether human brai

39 a mouse model to investigate the effects of clinical doses of etoposide on the induction of chromoso

40 a basic science finding (acute tolerance to clinical doses of methylphenidate) into clinical applica

41 e data indicate that while mothers receiving clinical doses of sertraline experience substantial bloc

42 sus controls), and caused less bleeding than clinical-dose r-tPA (P<0.001).

43 ation, causing more embolus dissolution than clinical-dose r-tPA alone (P<0.001) or alpha2-antiplasmi

44 T 719 treatment was compared with a standard clinical dose regimen of 25 mg/kg/day 5-FU/leucovorin gi

45 P and adenosine beyond currently recommended clinical doses resulted in a significant increase in cor

46 CT irradiation at typical clinical doses results in oversensing of ICRMDs in the m

47 smaller scale that is required for animal or clinical doses/sampling.

48 than that of bortezomib administered on its clinical dosing schedule.

49 paramagnetic ion concentration in a typical clinical dose) showed persistent (up to at least 2 hours

50 ntibiotic concentrations (when available) in clinical dosing software, which uses pharmacokinetic/pha

51 f these particles released approximately two clinical doses spaced a month apart.

52 This could affect clinical dose tailoring, especially in children.

53 nical trial simulations are used to identify clinical doses that achieve these kill rates in children

54 d mice that, when delivered at the same high clinical dose, the human IFN-alpha14 subtype has very po

55 The computer software is applicable as a clinical dosing tool to optimize tacrolimus exposure and

56 Clinical doses were able to be prepared and passed all q

57 and vinorelbine seem to correlate with their clinical doses, where vincristine with the highest overa