ライフサイエンスコーパス: clinical isolate

1 were indistinguishable from that of a human clinical isolate.

2 to that of an early passage of the original clinical isolate.

3 ith sublethal inocula of a hypervirulent XDR clinical isolate.

4 dilution susceptibility test results for 100 clinical isolates.

5 ghly active also against multidrug-resistant clinical isolates.

6 ation induced by both laboratory strains and clinical isolates.

7 different phenotypes commonly observed in CF clinical isolates.

8 thereby inhibiting anti-OmpA MAb binding to clinical isolates.

9 which has been shown to be heterogeneous in clinical isolates.

10 same genomic locus, as well as in 15 Indian clinical isolates.

11 matched the multilocus sequence type of the clinical isolates.

12 identify species and resistance profiles of clinical isolates.

13 ed close relationships among meat-source and clinical isolates.

14 sm and the observed low CRISPR prevalence in clinical isolates.

15 00% (95% CI, 63.06% to 100.00%) when used on clinical isolates.

16 ce types occurred among both meat-source and clinical isolates.

17 esistant to tetracycline and gentamicin than clinical isolates.

18 eroglycans were co-expressed on 63% of these clinical isolates.

19 more factors required for the replication of clinical isolates.

20 s widely conserved in a collection of recent clinical isolates.

21 easing resistance of Propionibacterium acnes clinical isolates.

22 ) have been observed in numerous strains and clinical isolates.

23 side whole-genome sequencing analysis of the clinical isolates.

24 -resistant mutants and a wide range of HIV-1 clinical isolates.

25 on mechanism of beta-lactam resistance among clinical isolates.

26 -indicative amplicon found in some serovar 6 clinical isolates.

27 as identified from an analysis of available clinical isolates.

28 resistance to linezolid has been reported in clinical isolates.

29 en identified in the genomes of up to 70% of clinical isolates.

30 nce, in several S. aureus strains, including clinical isolates.

31 ed with resistance to three anti-TB drugs in clinical isolates.

32 ing and -inhibitory factors were observed in clinical isolates.

33 d antimicrobial resistance gene detection in clinical isolates.

34 against a panel of genetically distinct HCMV clinical isolates.

35 reservoirs lyse a diverse array of MDR ST131 clinical isolates.

36 select training classes and performed WGS on clinical isolates.

37 cal for evaluations involving mostly routine clinical isolates.

38 l strains examined, including several Indian clinical isolates.

39 galectin-8, and Siglec-14, to different NTHi clinical isolates.

40 ch repair defect is prevalent in C. glabrata clinical isolates.

41 gainst 107 carbapenem-resistant A. baumannii clinical isolates.

42 In contrast, in a pair of clinical isolates 03-149.1 (polymyxin-susceptible) and 0

43 Results were confirmed with 2 additional RSV clinical isolates, 12/11-19 and 12/12-6, with known huma

44 f group 1 pilins on Tfp in the P. aeruginosa clinical isolate 1244.

45 9 non-CP isolates) as well as 45 prospective clinical isolates (15 CP-CRE and 30 non-CP-CRE) obtained

46 le to perform molecular investigations on 19 clinical isolates: 18 were classic haplotypes with addit

47 g pneumococcal colonization with either of 2 clinical isolates, 19F or 7F.

48 Thus, the clinical isolate 2-20 F protein function depended more o

49 uirement for RSV using G and F proteins from clinical isolate 2-20.

50 nel hospitals in 36 countries submitted 2703 clinical isolates (2301 [85%] K pneumoniae and 402 (15%)

51 s) and 161 contrived samples inoculated with clinical isolates (40 C. glabrata, 46 C. albicans, 36 C.

52 Of the 649 E. coli clinical isolates, 5 (0.8%) consistently produced nonsus

53 ually invariant among global B. pseudomallei clinical isolates, a Cambodian isolate varies only in C-

54 However, in certain GBS clinical isolates, a point mutation in rgfA results in p

55 GA2F [kRSV-A2GA2F] and kRSV-GstopA2F) or the clinical isolate A2001/2-20 (kRSV-2-20G2-20F and kRSV-Gs

56 The clinical isolate also had increased survival in blood an

57 A total of 130 clinical isolates and 129 clinical specimens were studie

58 t lines, as well as P. falciparum Senegalese clinical isolates and a short-term-culture-adapted strai

59 This gene is highly enriched in E. faecium clinical isolates and absent in commensal isolates that

60 also demonstrated in Acinetobacter baumannii clinical isolates and approximately 50% of clinical isol

61 o test competition between four ribotype 027 clinical isolates and clinical isolates of four other ri

62 tion of each of these factors varies between clinical isolates and corresponds to the capacity of eac

63 est the efficacy of our approach on numerous clinical isolates and demonstrate a 2-d reduction in dia

64 ibility are available due to the scarcity of clinical isolates and difficulty in performing susceptib

65 M was found toward a panel of 75 RSV A and B clinical isolates and dose-dependent antiviral efficacy

66 aureus and vancomycin-resistant Enterococci clinical isolates and inhibit mutant DNA gyrase in-vitro

67 lymphokine production was observed with most clinical isolates and laboratory HCMV strains, HCMV-perm

68 of mixed- Candida species biofilms formed by clinical isolates and laboratory strains in the presence

69 Clinical isolates and mutant Trichomonas CPI-GC that had

70 Three isolates each (two clinical isolates and one reference strain) of Staphyloc

71 This dMAb neutralized diverse CHIKV clinical isolates and protected mice from viral challeng

72 This approach can be used to classify clinical isolates and provides a universal framework for

73 fampin and isoniazid resistance detection on clinical isolates and smear-positive specimens.

74 cC, and adk) and applied to 55 M. pneumoniae clinical isolates and the two type strains M129 and FH.

75 equenced to closure the genomes of two ST258 clinical isolates and used these genomes as references f

76 eriophages are prevalent among P. aeruginosa clinical isolates and were detected in CF sputum.

77 Ab neutralization of HMGB1, infection with a clinical isolate, and recombinant HMGB1 treatment of res

78 se activity was characterized from 44 ocular clinical isolates, and a higher frequency of protease-po

79 sequenced and assembled four M. sympodialis clinical isolates, and showed their value for understand

80 al isolates are Type II, and Colombia, where clinical isolates are generally "atypical" or Type I-lik

81 However, 15 to 50% of clinical isolates are negative for known adhesins, makin

82 isolate from this patient and 39 additional clinical isolates are presented.

83 ited States, where approximately one-half of clinical isolates are Type II, and Colombia, where clini

84 studies of galectin-binding diversity among clinical isolates as a possible source for symptom dispa

85 types (MLSTs), including human commensal and clinical isolates as well as isolates from animals and o

86 ssing HIV-1 drug-resistant strains including clinical isolates, as well as simian immunodeficiency vi

87 t activity against VRE, inhibiting growth of clinical isolates at concentrations as low as 0.5 mug/mL

88 s the generation of native-like trimers from clinical isolates at high yields and homogeneity.

89 Previously, we have shown that clinical isolate-based recombinant mumps viruses lacking

90 analyses of four strains, H37Ra, H37Rv, and clinical isolates BND and JAL, to determine the differen

91 on with K. pneumoniae strain 43816 and three clinical isolates but did not increase susceptibility of

92 For JR-CSF and 92UG037, both tier 2 clinical isolates but different clades, DCSti-alt-MA exh

93 e contain substantially fewer genes than non-clinical isolates, but are more likely to encode virulen

94 tains activity against most Escherichia coli clinical isolates, but the growth of E. coli colonies wi

95 frequency differs greatly among pneumococcal clinical isolates, but the molecular basis and biologica

96 ella growth; 11 isolates were identical to 3 clinical isolates by sequence-based typing.

97 Recent work revealed that P. acnes clinical isolates can be classified into distinct phylot

98 We sequenced the genomes of 51 MRSA clinical isolates collected between 1999 and 2012 from t

99 performed on 649 multidrug-resistant E. coli clinical isolates collected between 2011 and 2015.

100 Therefore, invasion mechanisms of clinical isolates collected from 3 zones of Ghana with d

101 tested through the analysis of 375 different clinical isolates collected from distinct patient sample

102 d sequencing data for 451 patients and their clinical isolates collected in a multinational, observat

103 Clinical isolates collected in western Kenya pre- and po

104 of the method in vitro to a collection of 94 clinical isolates collected over a 4-year period in thre

105 demonstrated increased adhesion forces for a clinical isolate compared with the lab strain.

106 The observed synergy was tested against clinical isolates confirming synergy with Clarithromycin

107 close genetic relatedness of meat-source and clinical isolates, coupled with similarities in virulenc

108 been well characterized, particularly among clinical isolates derived in the United States.

109 Almost one-half (49/118) of the clinical isolates did not possess any known AAF major fi

110 Accordingly, Staphylococcus aureus clinical isolates differ substantially in their capacity

111 source of infection in both cases, with the clinical isolates differing from the likely infecting en

112 We further demonstrate that specific GAS clinical isolates display high affinity for the D-domain

113 ins, including pathogenic and drug-resistant clinical isolates, DNA adenine methyltransferase deficie

114 ences across a diverse panel of A. baumannii clinical isolates during murine bacteremia to elucidate

115 The complete agg5DCBA gene cluster from a clinical isolate, EAEC strain C338-14, with the typical

116 m-sensing system, which frequently occurs in clinical isolates, enhances S. aureus survival during da

117 Envs of different clinical isolates exhibit different sensitivities to ant

118 drug-resistant Stenotrophomonas maltophilia clinical isolate expressing L1.

119 As routine testing of clinical isolates for extended-spectrum beta-lactamase (

120 We further show that the clinical isolates frequently protect each other from cli

121 y screen of Burkholderia gladioli BCC0238, a clinical isolate from a cystic fibrosis patient, led to

122 erformed genome-wide sequence analysis of 52 clinical isolates from 2008 to prospect for loci under r

123 We assessed 1133 consecutive unique E. coli clinical isolates from 5 medical centers (2010-2011) for

124 Eighty USA300 MRSA clinical isolates from 74 trainees, 6 (8.1%) of whom had

125 ct was observed in laboratory strains and in clinical isolates from a recent California pertussis epi

126 ut to assess species identity of a set of 34 clinical isolates from Aspergillus section Circumdati fr

127 ully applied to multiplexed sequencing of 16 clinical isolates from India.

128 XCL-1 proteins from 11 different clades from clinical isolates from infants infected congenitally wit

129 rom the water systems of 17 hospitals and 42 clinical isolates from patients with confirmed or suspec

130 FnBPB) in 10 distinct, methicillin-resistant clinical isolates from patients with either persistent o

131 Pseudomonas aeruginosa clinical isolates from SCUT were evaluated for in vitro

132 Laboratory investigation using P aeruginosa clinical isolates from the double-blind Steroids for Cor

133 Clinical isolates from the most recent outbreak in the A

134 ct comparisons within and among populations, clinical isolates from three different West African site

135 luated the distribution of TPS systems among clinical isolates from two prospective cohort studies co

136 ital AST (dAST) determined susceptibility of clinical isolates from urinary tract infections (UTIs) a

137 ified 36 M. pneumoniae reference strains and clinical isolates from various geographic origins, inclu

138 values against all tested strains including clinical isolates harboring resistance to atovaquone.

139 The second clinical isolate harbors a novel plasmid that encodes th

140 Studies in clinical isolates have implicated multiple mechanisms in

141 fter an i.v. infection with a Brazilian ZIKV clinical isolate (HS-2015-BA-01) in rhesus macaques for

142 typed HIV-1 representing diverse subtypes of clinical isolates (IC50 as low as 270 nM).

143 Molecular fingerprinting of clinical isolates identified 2 clonal strains of M. absc

144 prp and cps amplicons were detected only in clinical isolates identified as belonging to the ST36 cl

145 ters of CGS parasites, was present in 24% of clinical isolates in 2008, declined to 3.4% of clinical

146 inical isolates in 2008, declined to 3.4% of clinical isolates in 2009, and then disappeared.

147 Nearly 25% of K. pneumoniae clinical isolates in a US network of LTACHs were CRKP.

148 However, it is still challenging to grow HCV clinical isolates in cell culture.

149 irregularis and the mating type ratio of 17 clinical isolates in China.

150 roperty and biofilm producing ability of the clinical isolates in chronic rhinosinusitis and orbital

151 onments as Pentobra was bactericidal against clinical isolates in comedones extracts isolated from hu

152 rythrocytic Developmental Cycle (IDC) of two clinical isolates in high resolution by Illumina HiSeq p

153 undances of P. aeruginosa transcripts across clinical isolates, in serial samples, and for the purpos

154 ood activity against several M. tuberculosis clinical isolates, including four that are resistant to

155 wide range of multidrug-resistant bacterial clinical isolates, including methicillin-resistant Staph

156 Whereas 77.7% (28/36) of clinical isolates indicated multidrug resistant (MDR) pa

157 identification of infectious pathogens from clinical isolates is a critical need in the hospital set

158 fluoroquinolone-resistance in K. pneumoniae clinical isolates is reversed by expression of Gam.

159 Raman spectroscopic data for 31 A. baumannii clinical isolates labeled according to their pulsed-fiel

160 monocytogenesis 19115 and E. coli O157:H7), clinical isolates (methicillin-resistant S. aureus (MRSA

161 CTX) and ceftazidime (CAZ) against resistant clinical isolates (MIC reduction, 32-fold).

162 In a blinded analysis of 153 clinical isolates, microarray sensitivity for first-line

163 rain Rd and nontypeable H. influenzae (NTHi) clinical isolate NT127.

164 his electrochemical detection strategy using clinical isolates obtained from patients with hospital-a

165 es of either the laboratory Neff strain or a clinical isolate of A. castellaniiIn vitro real-time ima

166 re either coincubated with trophozoites of a clinical isolate of Acanthamoeba (genotype T4) or stimul

167 However, macrophages cocultured with the clinical isolate of Acanthamoeba produced significantly

168 s infections, ferrets were challenged with a clinical isolate of BDBV.

169 Both a laboratory strain and a clinical isolate of C. albicans were used for SCFS exper

170 t CHIKV using a CHIKV replicon cell line and clinical isolate of CHIKV of Central/East African genoty

171 are utilized by both a vaccine strain and a clinical isolate of CHIKV to mediate virus binding.

172 inoculated intravenously with a low-passage, clinical isolate of DENV-2, and this resulted in sustain

173 Oral gavage of BALB/c mice with a clinical isolate of extraintestinal pathogenic E. coli (

174 macrophage-orchestrated inflammation using a clinical isolate of HCMV (TR) and macrophages derived fr

175 lowing ocular challenge with a neurovirulent clinical isolate of HSV-1.

176 ibited the replication of HSV-2 and a recent clinical isolate of HSV-1.

177 A clinical isolate of methicillin-resistant S. aureus was

178 roach, we were able to clearly distinguish a clinical isolate of MTB from a nonTB species of the genu

179 sion of the corresponding glycoproteins of a clinical isolate of MuV (hMuV).

180 DNA clone of ZIKV that was generated using a clinical isolate of the Asian lineage.

181 A total of 78 clinical isolates of 13 Gram-negative species collected

182 The rectal and clinical isolates of all 9 men with paired isolates had

183 Fluoroquinolone-resistant clinical isolates of bacteria have emerged readily and r

184 acterial effect against multi-drug resistant clinical isolates of bacterial pathogens and include thr

185 vitro against numerous fluconazole-resistant clinical isolates of C. albicans and non-albicans specie

186 Drug-resistant clinical isolates of C. glabrata most commonly contain p

187 de absolute quantification of both stock and clinical isolates of E. coli in spiked blood within a br

188 The practice of screening clinical isolates of Enterobacteriaceae that test as sus

189 our mutant OmpC proteins from four different clinical isolates of Escherichia coli obtained sequentia

190 splayed activity against multidrug-resistant clinical isolates of Escherichia coli, Acinetobacter bau

191 s urease activity in vitro, including recent clinical isolates of Escherichia coli, Enterococcus faec

192 ry concentrations (MICs) of imipenem against clinical isolates of Eschericia coli and Klebsiella pneu

193 ween four ribotype 027 clinical isolates and clinical isolates of four other ribotypes (001, 002, 014

194 molecular target remains unchanged across 30 clinical isolates of HCoV-NL63 strains.

195 tifungal susceptibility patterns of multiple clinical isolates of Histoplasma representing different

196 substantial expansion to include a number of clinical isolates of important Gram-negative species-Ent

197 submicromolar efficacy against several human clinical isolates of influenza A viruses, including both

198 molecules rapidly accumulated in respective clinical isolates of interest including MDROs such as me

199 serotype 3 strains emerge frequently within clinical isolates of invasive diseases.

200 ted the first ten carbapenem non-susceptible clinical isolates of K pneumoniae or E coli and ten susc

201 ibiotics targeting Gram-negative bacteria on clinical isolates of Klebsiella pneumoniae, containing h

202 sight into the mechanisms by which resistant clinical isolates of L. donovani induce intracellular ev

203 human macrophages infected with 3 ATCC and 5 clinical isolates of L.V. guyanensis, and L.V. panamensi

204 s and found that PRELP binds the majority of clinical isolates of M. catarrhalis (n = 49) through int

205 We show that the majority of clinical isolates of M. catarrhalis (n = 49), but not ot

206 is of the emergence of drug resistance among clinical isolates of M. tuberculosis, we show that the a

207 against drug-susceptible and drug-resistant clinical isolates of M. tuberculosis.

208 reductions in all bloodstream infections and clinical isolates of methicillin-resistant Staphylococcu

209 aeruginosa, Staphylococcus aureus (including clinical isolates of MRSA and MSSA) and Staphylococcus e

210 ce in the laboratory using serially passaged clinical isolates of MRSA and MSSA.

211 ncing and drug susceptibility testing on 337 clinical isolates of Mycobacterium tuberculosis collecte

212 th this, strains with mutations in gatA from clinical isolates of Mycobacterium tuberculosis show inc

213 ortant when evaluating solithromycin against clinical isolates of N. gonorrhoeae.

214 xacin, and ofloxacin were determined for 100 clinical isolates of nontyphi Salmonella with or without

215 i clinical isolates and approximately 50% of clinical isolates of P. aeruginosa from chronic airway i

216 Determination of exoU expression in clinical isolates of P. aeruginosa may be helpful in dir

217 compounds showed increased activity against clinical isolates of P. aeruginosa, further confirming t

218 In clinical isolates of PBMCs from lymphangioleiomyomatosis

219 icrobial peptides may explain why nearly all clinical isolates of pneumococci conserve this enzyme de

220 Inspired by new data from 28 clinical isolates of Pseudomonas aeruginosa and strains

221 We identified here melanogenic clinical isolates of Pseudomonas aeruginosa with large c

222 We obtained 331 clinical isolates of S flexneri serotype 3a, including 2

223 ed, supernatants from laboratory strains and clinical isolates of S. aureus caused galectin-3 degrada

224 ervation of nonsynonymous SNPs in fnbA among clinical isolates of S. aureus that cause endovascular i

225 Among a collection of genetically diverse clinical isolates of S. aureus, community-associated met

226 The genomes of pre- and posttherapy MDR clinical isolates of Salmonella Typhimurium from a patie

227 was to determine the species diversity of 23 clinical isolates of Schizophyllum from the United State

228 UK, we collected and whole-genome sequenced clinical isolates of Shigella flexneri serotype 3a from

229 ricidal activity against multidrug-resistant clinical isolates of staphylococcus aureus, including me

230 d beta-lactam resistance in human and animal clinical isolates of Staphylococcus intermedius group, S

231 Beta-lactam resistant clinical isolates of Streptococcus pneumoniae contain al

232 nt impedance results were also obtained with clinical isolates of the four DENV serotypes verified by

233 Since its discovery in 1989, efforts to grow clinical isolates of the hepatitis C virus (HCV) in cell

234 fungin, and micafungin were assessed for 290 clinical isolates of the most representative pathogenic

235 se respiratory infection model, we show that clinical isolates often responsible for CA infections ar

236 information can be obtained from sequencing clinical isolates on a large scale, even well-characteri

237 fcpA(-) mutants, obtained from clinical isolates or by allelic exchange, had relatively

238 One clinical isolate, P94015, presented several striking pro

239 Of the 6 air/clinical isolate pairs available, 4 pairs were closely r

240 ntaining 20 KPC-positive and 80 KPC-negative clinical isolates, performed in triplicate (300 runs) de

241 pe appeared to be more virulent, most of our clinical isolates presented belonged to (-) mating type.

242 tudies performed using a panel of 80 curated clinical isolates, rates of essential and categorical ag

243 We sequenced the genomes of 133 clinical isolates recovered from 24 tertiary care hospit

244 ed to characterize 14 Salmonella Senftenberg clinical isolates recovered from multiple outbreaks in S

245 mparative genome sequencing of 83 additional clinical isolates recovered from patients at diverse geo

246 r associated phenotypes of 208 S. pneumoniae clinical isolates representing at least 30 serotypes.

247 Single-nucleotide polymorphisms (SNPs) in clinical isolates revealed a number of known resistance-

248 res on the P. vivax genome by sequencing 182 clinical isolates sampled from 11 countries across the g

249 in from Scotland than the low-passage-number clinical isolate SD90e from South Africa or laboratory s

250 In these clinical isolates, several gyrA and gyrB mutations confe

251 cation using CHIKV vaccine strain 181/25 and clinical isolate SL15649.

252 specificity (100%) when challenged with 145 clinical isolate-spiked fecal specimens.

253 ion experiments for two T. asahii strains, a clinical isolate stain CBS 2479 (T2) and an environmenta

254 89 isolates (including 50 human and 4 animal clinical isolates) stored in the National Collection of

255 We unexpectedly observed that the prototype clinical isolate strain V583 was actively killed by GI t

256 the newly sequenced SD90e low-passage-number clinical isolate strain, each from a different geographi

257 Studies of an invasive clinical isolate (strain R2866) show that strains expres

258 ymers directly at the surfaces of a range of clinical isolate strains, allowing rapid, facile and sim

259 y parallel first reporting of these genes in clinical isolates, suggesting ARGs in animal manure and

260 es, genotypically indistinguishable from the clinical isolate, supporting for the first time the dire

261 ory challenges encountered when dealing with clinical isolates suspicious for B. pseudomallei or clin

262 Among 30 clinical isolates tested, the sbp2 gene sequence was hig

263 f reversion for this strain and for a second clinical isolate that reverts at a similar frequency.

264 Here we produce gametocytes from parasite clinical isolates that displayed artemisinin resistance

265 ntified genetic elements over-represented in clinical isolates that increased in frequency throughout

266 ristics of six phenotypically distinct human clinical isolates that most closely resembled the type s

267 ere as MS-AFST, was assessed with a panel of clinical isolates that were selected to represent phenot

268 lence of two divergent Staphylococcus aureus clinical isolates (the USA300 strain LAC and the USA200

269 tion of Mycobacterium tuberculosis lineage 4 clinical isolates, the most geographically widespread ca

270 We studied putative serotype 35B clinical isolates to assess the uniformity of their sero

271 K. pneumoniae isolates were more likely than clinical isolates to be antibiotic resistant, which coul

272 cal A. baumannii isolates including 9 recent clinical isolates to develop colistin resistance through

273 It may be used to classify clinical isolates to evaluate tools to control the disea

274 r correctly identified 28 of 34 F. nucleatum clinical isolates to the subspecies level.

275 Here we use whole genome sequences from 204 clinical isolates to track the evolution and epidemiolog

276 nce with atovaquone for activity against the clinical isolates W2 and TM90-C2B, as well as the improv

277 Adaptation of 536_P7 to this clinical isolate was also evaluated in vitro and in vivo

278 The most prevalent species among clinical isolates was A. levis (72.7%), followed by A. f

279 Molecular characterization of clinical isolates was also performed.

280 The clade of 11 C. acnes clinical isolates was determined by MLST.

281 assing all ten serotypes and a collection of clinical isolates, we demonstrate concordance between re

282 y testing the supernatant of S. aureus human clinical isolates, we found that the degree of G2/M phas

283 Among 25 serogroup B Neisseria meningitidis clinical isolates, we identified four (16%) with high fa

284 le-genome analysis of a global collection of clinical isolates, we show that the majority of M. absce

285 In the largest ever study of clinical isolates, we surveyed adhesion of freshly colle

286 The six human clinical isolates were biochemically indistinguishable f

287 Subsequently, 44 Haemophilus clinical isolates were collected, and 36 isolates were i

288 es also contained mutated wcjE alleles, 11Av clinical isolates were composed of antigenically homogen

289 99 A. defectiva, G. adiacens, and G. elegans clinical isolates were determined by broth microdilution

290 Clinical isolates were identified as F. novicida based o

291 The analyses revealed that 22 of the clinical isolates were in the Schizophyllum radiatum cla

292 Multiplication rates of eleven new clinical isolates were measured after a few weeks of cul

293 m laboratory adapted parasite clones and new clinical isolates were measured, using a newly standardi

294 These ambiguous clinical isolates were provisionally named 11A variant (

295 The S. halichoeri type strain and the human clinical isolates were susceptible to the antimicrobials

296 s observed when they were tested against six clinical isolates, which included extensively drug-resis

297 rmed genomic and plasmid sequencing of three clinical isolates with both MinION and Illumina MiSeq, u

298 revealed that while Fusobacterium nucleatum clinical isolates with FadA and Fap2 adhesins failed to

299 were confirmed in infection experiments with clinical isolates with known cagA status and in human ga

300 DNA extracted from E. coli or K. pneumoniae clinical isolates within a few minutes.

301 WGS clustered food, environmental, and clinical isolates within each outbreak, and also differe