ライフサイエンスコーパス: clinical management

1 fects, with potential implications for their clinical management.

2 h HGBL-DH is important because it may change clinical management.

3 early etiology-based diagnosis and improved clinical management.

4 thus might have a crucial impact on further clinical management.

5 netic similarities has led to their improved clinical management.

6 revalence of distress, with implications for clinical management.

7 agnosis of dental wear lesions affects their clinical management.

8 select patients with breast cancer to guide clinical management.

9 iceptors may help transform pain science and clinical management.

10 the underlying disease processes for better clinical management.

11 sequencing of RAS/BRAF is necessary to guide clinical management.

12 evant in the establishment of stage-specific clinical management.

13 ary data demonstrate a substantial impact on clinical management.

14 iod, and characteristics allows for tailored clinical management.

15 g may provide new insights into etiology and clinical management.

16 ctors should be investigated for appropriate clinical management.

17 g medically evacuated to other countries for clinical management.

18 ular phenotypes, raising major challenges in clinical management.

19 levels are misleading parameters for guiding clinical management.

20 pes of avian influenza viruses to help guide clinical management.

21 ating and require lifetime multidisciplinary clinical management.

22 nd other cancers remains a major obstacle to clinical management.

23 ases can substantially influence the further clinical management.

24 dentify patients at risk earlier and improve clinical management.

25 athophysiology and to contribute to improved clinical management.

26 nderstood and this may have implications for clinical management.

27 adiograph markedly affect both diagnosis and clinical management.

28 development of clinical features and guiding clinical management.

29 and oxygenation, remains the cornerstone of clinical management.

30 s remains a major challenge of breast cancer clinical management.

31 which could have important implications for clinical management.

32 U) is not sufficiently timely to guide acute clinical management.

33 following LRA therapy, which will complicate clinical management.

34 ndemic granulomatous disease and may improve clinical management.

35 parameter to help determine the appropriate clinical management.

36 natal stroke informs pathogenesis models and clinical management.

37 rombocytopenia to relieve it and improve its clinical management.

38 unity is crucial for patients' prognosis and clinical management.

39 tuximab poses a challenge to their effective clinical management.

40 viral testing may play an important role in clinical management.

41 atification is a requirement for appropriate clinical management.

42 erapy, which is emerging as a cornerstone of clinical management.

43 I) pathogenesis and have been used to inform clinical management.

44 history of the disease and may better guide clinical management.

45 y 8 patients had abnormalities that affected clinical management.

46 k is increased, and ultimately contribute to clinical management.

47 for imaging is limited and has no impact in clinical management.

48 is one of the most challenging issues in the clinical management.

49 tic yield of WES and its potential effect on clinical management.

50 and this increase is creating challenges for clinical management.

51 accounted for in studies of etiology and in clinical management.

52 role in risk stratification and guidance of clinical management.

53 L and discuss the role of genomic testing in clinical management.

54 Despite advances in clinical management, 5-year survival rate in patients wi

55 d biomarkers, versus patients managed with a clinical management algorithm.

56 ts with Ebola virus disease to better inform clinical management algorithms, improve understanding of

57 n of Alzheimer disease (AD) is important for clinical management and affords the opportunity to asses

58 velopmental problems without the confound of clinical management and allows other potential risk fact

59 on range capability that may further improve clinical management and antimicrobial stewardship in pat

60 ms from positive blood cultures has improved clinical management and antimicrobial stewardship.

61 of lesions in retinal images is relevant to clinical management and clinical trials, but it is time-

62 The clinical management and diagnostics of such patients req

63 e in delivering healthcare, particularly for clinical management and disease surveillance in both dev

64 international centers with expertise in the clinical management and genetic architecture of hypertro

65 f understanding of the disorder has hindered clinical management and genetic counseling for the many

66 pulation-based screening of newborns can aid clinical management and help improve outcomes; it also p

67 of transplantation immunobiology has refined clinical management and improved outcomes.

68 findings may lead to a significant change in clinical management and independently predict mortality.

69 ted pathway will yield valuable insight into clinical management and may ameliorate colorectal cancer

70 ent of endophthalmitis following DEX and the clinical management and outcomes of each case of endopht

71 onary artery disease might affect subsequent clinical management and outcomes.

72 diagnostics of CCHF is vital for appropriate clinical management and prevention of secondary spread f

73 eptors, infers causal mechanisms relevant to clinical management and prevention, and suggests balanci

74 s, understanding these processes may improve clinical management and public health disease control.

75 esistance in this population will facilitate clinical management and rational therapeutic development

76 tant findings that may have implications for clinical management and surgical planning.

77 Despite improvement in the clinical management and survival ( approximately 85-90%)

78 linical assessments, and might have a use in clinical management and the evaluation of new therapies.

79 ledge of the skin microbiome will inform the clinical management and treatment of skin disorders thro

80 ge of domains, including mapping, diagnosis, clinical management, and community control measures such

81 natural history, patient stratification and clinical management, and ending with an overview of emer

82 ally meaningful criteria for CAABMR, for its clinical management, and in the future selection of popu

83 s and an absence of randomised trials hinder clinical management, and longstanding controversies such

84 This review summarizes the biology, clinical management, and pharmacological perspectives of

85 zed diseases, to improve recommendations for clinical management, and to advance research, especially

86 n their behavior and the strategies used for clinical management are highly variable.

87 tions that are well known but their roles in clinical management are not yet certain.

88 on the emerging role for mutational data in clinical management as a potential tool to assist in dia

89 Changes in diagnosis, prognosis, and clinical management brought about by iuMRI and patient a

90 catalyzed reconsiderations of approaches to clinical management, but also have stimulated debate abo

91 of novel zoonotic pathogens represent major clinical management challenges worldwide.

92 ients found abnormal transit in 72% (13/18); clinical management changed in 61% (11/18).

93 Clinical management changes resulting from ophthalmic co

94 ears to be quite sensitive and effective for clinical management decision making.

95 Increasingly, clinical management decisions and the development of inv

96 diagnostic grey zone should be considered in clinical management decisions in patients with these dia

97 Several clinical management decisions in rectal cancer may be in

98 e expected to contribute to more appropriate clinical management decisions.

99 tion provided by single biopsy fragments for clinical management decisions.

100 e study, and the primary outcome depended on clinical management decisions.

101 Clinical management depended on histological grade, with

102 The clinical management depends entirely on the type of prot

103 amydia pathway who then received appropriate clinical management either exclusively through online tr

104 e can be reversed in many patients, and thus clinical management focuses upon the identification and

105 Without robust pediatric data, clinical management follows international guidelines tha

106 tibiotics should be regarded as advocates in clinical management for detected fGGOs.

107 s, or another genetic syndrome can influence clinical management for patients with CRC and their fami

108 s because most identified genes could change clinical management for some patients.

109 assessment yielded findings likely to change clinical management for substantially more patients than

110 n with atopic dermatitis (AD), but effective clinical management for this problem is lacking.

111 ns with a known genotype and can improve the clinical management, genetic counseling, and risk assess

112 ek 48 (56 [46%] of 122 patients) than in the clinical management group (37 [30%] of 122 patients), wi

113 points compared with baseline or CDAI >200; clinical management group after random assignment: CDAI

114 29 (24%) patients in the clinical management group and 32 (26%) patients in the t

115 150, or prednisone use in the previous week; clinical management group before random assignment: CDAI

116 l group and 100 (82%) of 122 patients in the clinical management group reported treatment-emergent ad

117 , 2016, 244 patients (mean disease duration: clinical management group, 0.9 years [SD 1.7]; tight con

118 16%]), and nasopharyngitis (18 [15%]) in the clinical management group.

119 assigned at a 1:1 ratio to tight control or clinical management groups, stratified by smoking status

120 Clinical management guidelines for patients with germlin

121 nsuspected disease and may influence planned clinical management in a high proportion of patients wit

122 to a precise lymphoma diagnosis and optimal clinical management in a proportion of patients.

123 However, integrating them into clinical management in an individualized manner has prov

124 letes, but their widespread dissemination to clinical management in emergency departments and communi

125 Guidelines for clinical management in Li-Fraumeni syndrome, a multiple-

126 in at least 157 (20%), and led to changes in clinical management in more than one in three cases.

127 The results affected clinical management in most identified cases, including

128 ut their toxic effect profiles need thorough clinical management in specialised centres.

129 us develop adenocarcinoma, which complicates clinical management in the absence of valid predictors.

130 o risk factors and possible implications for clinical management in the further exploration of human

131 ack of a biomarker hinders the diagnosis and clinical management in these patients.

132 pragmatic approach that we hope will enhance clinical management in this area.

133 These clinical management initiatives, instituted by the pract

134 Clinical management involving the early use of ultrasoun

135 Clinical management is based on individual evaluations a

136 ocused on eradicating disease and optimizing clinical management is essential.

137 Clinical management is stage based; however, there is wi

138 e, whether finding such mutations will alter clinical management is unknown.

139 dren had 339 OCT sessions over the course of clinical management (median number of OCT scans per eye,

140 rial on the efficacy of group psychotherapy, clinical management, methylphenidate, and placebo (Compa

141 , respectively, (18)F-FDG PET/CT altered the clinical management of 5 and 3 patients, respectively.

142 herence tomography (OCT) has transformed the clinical management of a myriad of ophthalmic conditions

143 holds the potential for both research on and clinical management of a variety of cancers.Background o

144 strategy for the delivery of therapeutics in clinical management of acute brain injuries.

145 These data identify priorities for clinical management of adults and children with IMD, and

146 used and pragmatic randomized studies on the clinical management of AF.

147 allow their translation into practice in the clinical management of allergic disease.

148 omarkers of neuronal damage could facilitate clinical management of and therapeutic development for H

149 t if cAMP-based therapy is considered in the clinical management of APL.

150 glucocorticoids (GCs) are a mainstay in the clinical management of asthma, the target cells that med

151 Current clinical management of betaT is a lifelong dependence on

152 constitute an important step forward in the clinical management of bipolar disorder.

153 The clinical management of BRCA1 and BRCA2 mutation carriers

154 iding exciting new therapeutic strategies in clinical management of cancer beyond the conventional cy

155 nalized medicine and target treatment in the clinical management of cancer patients has become increa

156 profiling of tumors promises to advance the clinical management of cancer, but the benefits of integ

157 perhaps the greatest challenge to effective clinical management of cancer.

158 astasis, which is the greatest impediment to clinical management of cancers today.

159 ng need for predictive biomarkers to improve clinical management of cervical cancer patients.

160 Organization recommended guidelines for the clinical management of childhood diarrhea.

161 heavy-chain variable region are important in clinical management of chronic lymphocytic leukemia.

162 effects of opioids and its implications for clinical management of CNCP within the framework of rece

163 er the past few decades have transformed the clinical management of congenital heart disease, such as

164 Significant advances have been made in the clinical management of craniofacial disorders, but curre

165 ould significantly improve the diagnosis and clinical management of cystinuria.

166 Prior to 2010, the clinical management of dengue in Puerto Rico was inconsi

167 vances, significant challenges remain in the clinical management of dengue-infected patients, especia

168 Clinical management of diabetes must address age- and se

169 opens up new therapeutic strategies for the clinical management of diabetes.

170 pes, severe asthma, acute exacerbations, and clinical management of disease in adults and children ol

171 However, their wider application in the clinical management of disease is barred by poor aqueous

172 results may have an important impact on the clinical management of DLBCL patients with MYC-R who sho

173 Clinical management of Ebola virus disease remains chall

174 patients with Ebola virus disease (EVD) and clinical management of EVD in settings outside West Afri

175 ) of incidental findings was determined, and clinical management of findings that required the attent

176 standardized and well-validated tool for the clinical management of fungal infections and for epidemi

177 GBS in Zika virus-infected persons, and the clinical management of GBS cases.

178 Persons with retinopathy may warrant closer clinical management of general health.

179 HEP-SIM simulated the actual clinical management of HCV from 2001 onward, which inclu

180 This report provides guidelines for clinical management of hematologic cancers during the pe

181 ine kinase inhibitors (TKIs) are used in the clinical management of hematological neoplasms.

182 gnostic and therapeutic consequences for the clinical management of HER2(+) breast cancer.

183 oL is emerging as an important aspect of the clinical management of HF that can reduce disease burden

184 y is an acceptable alternative for long-term clinical management of HIV infection.

185 1 RNA has become the standard of care in the clinical management of HIV-1-infected individuals.

186 dy evaluated the effect of the course on the clinical management of hospitalized dengue patients.

187 g resistance remains a core challenge in the clinical management of human cancer, including in urothe

188 ovide a basis for incorporating 2HG MRS into clinical management of IDH-mutated gliomas.

189 mulation of SIM may have great potential for clinical management of impaired fracture healing.

190 monitoring could play a critical role in the clinical management of influenza virus infection and an

191 Delphi process to identify consensus in the clinical management of intracranial germ-cell tumours.

192 bility of fungal pathogens is central to the clinical management of invasive fungal disease.

193 that it might be appropriate to stratify the clinical management of LFS according to the class of the

194 be a useful adjunctive tool in diagnosis and clinical management of LN.

195 gnostic and therapeutic tools to improve the clinical management of Lyme disease.

196 ese findings have potential to influence the clinical management of male osteoporosis.

197 the existing literature and discuss optimum clinical management of meningoencephalitis caused by C g

198 validated in prospective trials in MMel.The clinical management of metastatic melanoma requires pred

199 tform for translational research and for the clinical management of myeloid malignancies, which can b

200 ic therapy are now the central tenets of the clinical management of necrotising fasciitis; these trea

201 econdary outcomes included the knowledge and clinical management of neonatal resuscitation (skills) o

202 ions for the homeostatic pathophysiology and clinical management of neurodegenerative diseases.

203 This has important implications for the clinical management of neuroendocrine prostate cancer as

204 To facilitate the clinical management of novel cases of MINAS, we have est

205 ility of targeted sequencing of ctDNA in the clinical management of NSCLC.

206 a potential utility of this approach in the clinical management of NSCLC.

207 e, evidence-based decision making now guides clinical management of PAH and improves outcomes.

208 the goal of utilizing cancer genomics in the clinical management of pancreatic cancer.

209 The clinical management of paroxysmal nocturnal hemoglobinur

210 sis has greatly influenced the diagnosis and clinical management of patients affected by diverse form

211 low and provide detailed information for the clinical management of patients and public health interv

212 w multimodality imaging can be integrated in clinical management of patients at risk of AF and stroke

213 The HLA association could support clinical management of patients experiencing hepatotoxic

214 Clinical management of patients receiving AIT and effica

215 teomic assays have been extensively used for clinical management of patients with amyloidosis, provid

216 ma 2 have opened up new opportunities in the clinical management of patients with CLL and heralded a

217 Despite extensive efforts to improve the clinical management of patients with colorectal cancer,

218 receptors), and discuss its potential in the clinical management of patients with drug-resistant and

219 nditions could play an important role in the clinical management of patients with GBM and other brain

220 Clinical management of patients with germline CYLD mutat

221 or the increased use of the procedure in the clinical management of patients with HF.

222 nd (EUS) and other imaging modalities in the clinical management of patients with idiopathic ARP.

223 ic utility, with the potential to change the clinical management of patients with infectious diseases

224 onsensus that will help guide and streamline clinical management of patients with intracranial germ-c

225 merged as a significant factor affecting the clinical management of patients with invasive fungal inf

226 This has important implications for the clinical management of patients with localized PC, as su

227 F may provide useful adjunctive data for the clinical management of patients with outbreak-associated

228 Our findings provide a method to improve the clinical management of patients with thyroid nodules whi

229 Thus this biosensor may improve the clinical management of patients with trauma-induced coag

230 gnificant implications for the diagnosis and clinical management of patients.

231 netic research and their potential to affect clinical management of patients.

232 indings may be interpreted and influence our clinical management of patients.

233 osis of high-risk populations and assist the clinical management of patients.

234 have already had a remarkable impact on the clinical management of PC.

235 ociated with incorporating genomics into the clinical management of pediatric patients with brain tum

236 discuss available literature on the topic of clinical management of people infected with HIV, hepatit

237 suggest that this compound is effective for clinical management of persistent and chronic pain and e

238 stic application and may help to improve the clinical management of prostate cancer in the future.

239 The clinical management of severe pain depends heavily on op

240 This is a novel strategy for clinical management of shellfish allergy and is a model

241 iation has been extensively employed for the clinical management of solid tumors, with therapeutic or

242 , and outlines new approaches to improve the clinical management of STIs and public health.

243 The clinical management of such patients requires a multidis

244 es these advances and their implications for clinical management of the ACS for the future.

245 further discuss the impact of obesity on the clinical management of the disease and examine the devel

246 This finding should influence clinical management of the disease and informs targeted

247 osed natural history of JOCD to better guide clinical management of the disease.

248 ecessary exposure to technical expertise and clinical management of the patient undergoing bariatric

249 As OCT transformed the clinical management of the vitreoretinal conditions, iOC

250 ork, which consists of expert centers in the clinical management of these disorders, has formulated t

251 Incorporation of this approach into clinical management of these patients should be consider

252 ognostic factors are awaited to optimize the clinical management of these patients.

253 es and a step towards the improvement of the clinical management of these patients.

254 ogenesis of PAH with the goal to improve the clinical management of this devastating disease.

255 breast cancer pose the primary challenge in clinical management of this disease, demanding the ident

256 oped a comprehensive registry to assist with clinical management of this lead.

257 egulation, remain largely elusive, hampering clinical management of this malignancy.

258 ine the potential role for this assay in the clinical management of this patient subset.

259 A fundamental challenge in the clinical management of this population is that it is not

260 This compendium will review the clinical management of those surviving SCD and discuss l

261 exities of the natural history, biology, and clinical management of three intermediate connective tis

262 iated therapeutic targets, may influence the clinical management of trauma patients.

263 The clinical management of tuberculosis is a major challenge

264 ly with systemic chemotherapy to improve the clinical management of UCB, based on evidence that these

265 ic chemotherapy as a strategy to improve the clinical management of UCB.Significance: These findings

266 Clinical management of Wilson's disease, autoimmune live

267 pment of specific antiviral therapeutics for clinical management of yellow fever.

268 ar aims to provide insights into the current clinical management, ongoing controversies, and future n

269 rence compared with those assigned to either clinical management or continuation of antidepressant me

270 initial decisions around ART initiation and clinical management, particularly for patients presentin

271 We used the PEP clinical management pathway and the Grading of Evidence,

272 d the clinical rationale for MR imaging, the clinical management plan if MR imaging was not an option

273 l management, the surgeon's comfort with the clinical management plan, and post-test diagnostic certa

274 up in 1997, and the better surveillance and clinical management practices initiated under STEP led t

275 ow birth weight (VLBW) is necessary to guide clinical management, provide information to parents, and

276 be accepted as having DIF-negative MMP, for clinical management purposes, with patients having infla

277 We present 7 vignettes to illustrate common clinical management questions that arise during the cour

278 We summarize our findings and provide clinical management recommendations.

279 eous tumor of unknown pathogenesis for which clinical management remains unsatisfactory.

280 n, Department of Veterans Affairs Center for Clinical Management Research, University of Michigan Spe

281 ure progress, applied medical knowledge, and clinical management; results may determine promotion and

282 ssociations within the context of real-world clinical management settings, where varying durations of

283 d be taken into consideration for optimizing clinical management strategies for inflammatory bowel di

284 Refinement in clinical management strategies for patients with cirrhos

285 These conditions require different clinical management strategies than HEDS, and left untre

286 ation and progression will require different clinical management strategies.

287 but they omit features that are important in clinical management, such as rate of progression, geneti

288 t survey assessing if/how MR imaging changed clinical management, the surgeon's comfort with the clin

289 vides risk stratification useful for guiding clinical management; the risk among HPV16-positive women

290 ges for applying prostate cancer genomics to clinical management, this review will incorporate some o

291 tions could assist physicians to personalize clinical management to mitigate the risk of thrombosis.

292 ncepts and provide a personal perspective on clinical management today and future directions of treat

293 prising educational outreach to nurses and a clinical management tool with enhanced prescribing provi

294 This case offers a guideline for the clinical management towards survival of GITB in transpla

295 dian rhythms in atherosclerosis will enhance clinical management, treatment, and public health policy

296 gnoses were unexpected in 8 of 23 (35%), and clinical management was altered in 6 of 23 (26%).

297 A 4-hour classroom-style course on dengue clinical management was developed in 2009 and mandated f

298 of integrative clinical sequencing data into clinical management was feasible, revealed potentially a

299 subtypes with implications for prognosis and clinical management were identified.

300 ter delineates the state of prostate cancer, clinical management will evolve.