ライフサイエンスコーパス: clinical research

1 CSF should be used in clinical practice and clinical research.

2 ntation could also become a topic for future clinical research.

3 Relevance: Sex bias exists in human surgical clinical research.

4 t explosion in the nanobody use in basic and clinical research.

5 eristics, making them useful instruments for clinical research.

6 ridge the gaps between cell line, animal and clinical research.

7 novel PET tracers and provided key tools for clinical research.

8 a wealth of opportunity for biomarker-driven clinical research.

9 wledge from many areas of basic, applied and clinical research.

10 content in human osteoarthritis subjects in clinical research.

11 icacy testing of immunotherapy and for basic clinical research.

12 of synchronous neural activity for basic and clinical research.

13 has recently emerged as a promising tool for clinical research.

14 a variable that is poorly controlled for in clinical research.

15 s) are an increasingly utilized resource for clinical research.

16 or human-based cellular models for basic and clinical research.

17 accessibility mapping in cancer cohorts and clinical research.

18 feasibility, and transparency define useful clinical research.

19 ransplantation; and V.Suggestions for future clinical research.

20 is testing methods are frequently misused in clinical research.

21 on language and procedures are being used in clinical research.

22 ry (LC/ESI-MRM-MS) are more commonly used in clinical research.

23 high-throughput phenotyping for genetic and clinical research.

24 rone, has been subject to rigorous basic and clinical research.

25 anagement and identify directions for future clinical research.

26 ss or spatial) to be more readily applied to clinical research.

27 phoproteomics in biological, biomedical, and clinical research.

28 Act was to ensure inclusion of minorities in clinical research.

29 pidomic analysis of large sample sets in the clinical research.

30 method can be beneficial for both basic and clinical research.

31 eagent for preclinical studies and for human clinical research.

32 t, pregnant women remain underrepresented in clinical research.

33 brain, but also in pathological contexts in clinical research.

34 s increasingly being viewed as essential for clinical research.

35 Oncolytic viruses are an active area of clinical research.

36 ent at relapse offer ample opportunities for clinical research.

37 ractical considerations in PRO assessment in clinical research.

38 at is broadly revolutionizing biological and clinical research.

39 ut also transforming the way that we conduct clinical research.

40 or future clinical outcome prediction and in clinical research.

41 e in nearly all aspects of today's basic and clinical research.

42 ne use of nanoscale imaging in pathology and clinical research.

43 ogy and study design principles will improve clinical research, advance regulatory science, and foste

44 and Kraepelin shared both a commitment to a clinical research agenda for psychiatry (to utilize meth

45 n is to develop, prioritize, and implement a clinical research agenda that addresses the public healt

46 Research Council, Swedish State Support for Clinical Research, Alzheimer's Association, Knut and Ali

47 ic health records (EHRs) promises to advance clinical research and better inform clinical decision ma

48 s represents an important outcome measure in clinical research and clinical trials; further, survival

49 vir plus lamivudine regimen warrants further clinical research and consideration as a potential thera

50 comprehensive summary of the preclinical and clinical research and development of nintedanib from the

51 ing recent knowledge with the aim to support clinical research and drug development.

52 sitivity affects the way PET is used both in clinical research and in patient care.

53 ging with(43)K-potassium was introduced into clinical research and management of patients with corona

54 Data from clinical research and our previous study have suggested

55 ated the potential impact dPCR could have on clinical research and patient management by earlier (tra

56 ive proteomics in molecular systems biology, clinical research and personalized medicine.

57 kinetics tools, making it adaptable to both clinical research and possible diagnostic applications.

58 ma on QoL that is suitable for use in asthma clinical research and potentially in clinical care.

59 d to select the most effective PRO to use in clinical research and practice for anal cancer since no

60 k of IR and diabetes need to be evaluated in clinical research and practice.

61 symptom items for use as a validated PRO in clinical research and practice.

62 astatic castration-resistant prostate cancer clinical research and practice.

63 ection of patient-reported outcomes (PRO) in clinical research and routine care.

64 s and illustrates how they are being used in clinical research and the potential for their use in cli

65 ii) complexes have successfully been used in clinical research and their mechanisms of anticancer act

66 promise OLAG as a revolutionary tool in the clinical research and treatment of patients with patholo

67 ledge base that better informs the design of clinical research and trials in humans.

68 uded about whistle blowers, animal research, clinical research, and clinical trial registration, addr

69 Effective patient care, clinical research, and public health efforts require com

70 come measures are essential for high-quality clinical research, and quality-of-life (QoL) tools are t

71 elled by improved technology, evidence-based clinical research, and setting up of multidisciplinary h

72 of Incidental and Secondary Findings in the Clinical, Research, and Direct-to-Consumer Contexts ) re

73 ing and faculty competence and compliance in clinical, research, and educational roles.

74 In this Review, we present clinical, research, and policy recommendations to improv

75 Our results provide information essential to clinical, research, and public health laboratories perfo

76 nd warrants further investigation for use in clinical research applications that rely on health-care

77 For most clinical research applications, the SUVR approach is app

78 Thus, both basic and clinical research are needed to understand the full impa

79 As a result, 1) the results of clinical research are slow to have an impact on clinical

80 Incorporating epigenomic testing into the clinical research arsenal will greatly facilitate our un

81 ifepristone based on any new developments in clinical research as best practices continue to be updat

82 cells that has emerged from experimental and clinical research as well as pathology investigations.

83 /1593) by RDT performed by CHWs vs an expert clinical research assistant vs microscopy (gold standard

84 -related mortality was noted as excellent by clinical research associates (kappa=0.83, 95% CI 0.60-1.

85 ent between the consensus classifications by clinical research associates and paediatric oncologists

86 hs, which were independently assessed by two clinical research associates and two paediatric oncologi

87 This year's Lasker approximately DeBakey Clinical Research Award goes to James Allison for discov

88 pectrometry imaging (MSI) is widely used for clinical research because when combined with histopathol

89 iority design is used extensively in current clinical research, but its complex features may hamper t

90 ge of women authors was similar in basic and clinical research, but was steeper for first authorship

91 Oncologists interested in applying NLP for clinical research can play pivotal roles in building NLP

92 the expected results include greater global clinical research capacity in high-burden settings, and

93 The extramural General Clinical Research Center (GCRC) program has been funded

94 prospective controlled study took place at a clinical research center and included 24 patients with f

95 ultimodal imaging study was performed at the Clinical Research Center at Brookhaven National Laborato

96 A single-institution study at the Clinical Research Center at the National Institutes of H

97 Fifty patients were enrolled at the Clinical Research Center of the National Institutes of H

98 type 1 and HIV co-infection conducted at the Clinical Research Center of the National Institutes of H

99 The study was conducted in a clinical research center with the use of a counterbalanc

100 ormed a cross-sectional study at an academic clinical research center.

101 inical trial or an observational study at 40 clinical research centers across the United States.

102 d, double-blind, crossover clinical trial at clinical research centers in 4 US cities (October 2012-J

103 ters in the American Lung Association Asthma Clinical Research Centers network.

104 atients enrolled in 4 trials from the Asthma Clinical Research Centers were included in this analysis

105 es (hospital clinics, general practices, and clinical research centers) in 14 countries conducted bet

106 The setting included neurology clinics, clinical research centers, and hospitals in the Americas

107 ide association studies at multiple academic clinical research centers.

108 ial of the American Lung Association Airways Clinical Research Centers.

109 double-masked trials in 27 US and six German clinical research centres and sleep centres.

110 s per month were enrolled at 59 headache and clinical research centres in North America and Europe, a

111 onic migraine, enrolled from 69 headache and clinical research centres in North America and Europe.

112 (FEV1) of at least 12% at screening, from 52 clinical research centres in six countries.

113 ients with asthma aged 12-75 years (from 128 clinical research centres in study 1 and 104 centres in

114 leading the world in crafting new models of clinical research collaboration that hold the promise of

115 ctice was conducted across the network of UK Clinical Research Collaboration-registered trial units (

116 rited Neuropathies Consortium - Rare Disease Clinical Research Consortium (INC-RDCRC) between 2009 an

117 Digestive and Kidney Diseases Gastroparesis Clinical Research Consortium Gastroparesis Registry, see

118 herited Neuropathy Consortium--Rare Diseases Clinical Research Consortium on-line contact registry.

119 8) F-flortaucipir uptake in patients meeting clinical research criteria for PSP (n = 33) to normal co

120 arge-scale integration of model organism and clinical research data can provide a breadth of knowledg

121 he primary focus in interpreting therapeutic clinical research data should be on the treatment ("oomp

122 Based on results from Diabetic Retinopathy Clinical Research (DRCR) Network Protocol S, we performe

123 ome increasingly deployed in preclinical and clinical research due to its rapid and accurate readouts

124 g promise as therapeutics in a resurgence of clinical research during the past 10 years.

125 e.g. identifying motor-related proteins) and clinical research (e.g. identification of cancer biomark

126 Clinical research efforts have developed and demonstrate

127 However, large clinical research efforts in recent decades have identif

128 Both quality improvement and clinical research efforts over the past few decades have

129 l clinical challenges and help guide ongoing clinical research efforts.

130 anding initiative for enhancing trust in the clinical research enterprise.

131 Materials and Methods The clinical research ethics board approved chart review, an

132 easurement Set is recommended for use in all clinical research evaluating ARF survivors after hospita

133 esenting four stakeholder groups relevant to clinical research evaluating postdischarge outcomes of a

134 with insights from basic, translational, and clinical research, experts have a more comprehensive kno

135 rom June 16, 2011, to October 10, 2014, in a clinical research facility completed by 75 psychotropic

136 d MRC Clinical Pharmacology and Therapeutics Clinical Research Fellowship, National Institute for Hea

137 ing call to use patient-reported outcomes in clinical research, few are available for measuring upper

138 We discuss in-vitro and in-vivo basic and clinical research findings on the epidemiology, diagnosi

139 Flow cytometry is used increasingly in clinical research for cancer, immunology and vaccines.

140 ls-(18)F-FDG and (18)F-NaF-have been used in clinical research for imaging coronary artery plaque, an

141 In most epidemiologic studies and in clinical research generally, there are variables with a

142 Basic and clinical research has documented the important role circ

143 Clinical research has focused on early seizure terminati

144 Prior clinical research has focused on the efficacy and safety

145 Clinical research has proven to be too slow, unreliable,

146 Recent clinical research has provided evidence that cancer prog

147 numerous breakthroughs in basic science and clinical research have been made, augmenting our underst

148 alcohol use disorder.SIGNIFICANCE STATEMENT Clinical research identified cognitive deficits in alcoh

149 ts of immunotherapy with potential basic and clinical research implications.

150 n amyloid-beta (Abeta) continues to dominate clinical research in AD, a deeper understanding of Abeta

151 tools should be further improved by specific clinical research in OA.

152 the growing evidence from animal models and clinical research in other reproductive mood disorders w

153 Preclinical and clinical research in the field has contributed to an adv

154 The successful conduct of clinical research in the field of donation and transplan

155 eived and real that have hampered widespread clinical research in the field of donation and transplan

156 g the optimal infrastructure for overview of clinical research in the field should be given priority.

157 studies ecosystem for performing early-stage clinical research in the United States is necessary.

158 nces have been made in both experimental and clinical research in this area.

159 pproach contrasts with traditional models of clinical research in which researchers determine the stu

160 Projects in basic, applied, and clinical research, including epidemiological, public hea

161 Clinical research increasingly utilizes objective biolog

162 and Massachusetts General Hospital Leukemia Clinical Research Information Systems database.

163 of symptoms in preclinical models, a strong clinical research infrastructure highlighted by an NIH-f

164 PD/AG in a longitudinal study performed at 8 clinical research institutes and outpatient centers acro

165 Substantial preclinical and clinical research into chronic graft-versus-host disease

166 tive models of self, embodied cognition, and clinical research into memory deficits in psychiatric di

167 gs for daily practice and for the purpose of clinical research involving a core laboratory.

168 Progress in tuberculosis clinical research is hampered by a lack of reliable biom

169 Yet, this pinnacle of clinical research is itself afflicted.

170 He suggests most clinical research is not useful and reform is overdue.

171 Further clinical research is required before new oral anticoagul

172 Because clinical research is the foundation for evidence-based m

173 city has been greater for basic science than clinical research, it is natural to ask whether the dyna

174 Clinical research laboratory.

175 ever, many of us who have actually conducted clinical research, managed clinical studies and data col

176 clinicians, tinnitus researchers, experts on clinical research methodology, statisticians, and repres

177 ought to rest through the development of new clinical research methods that were capable of taking ad

178 Despite recent progress in both basic and clinical research, most pancreatic cancers are detected

179 The Diabetic Retinopathy Clinical Research Network (DRCR Network), sponsored by t

180 Diabetic Retinopathy Clinical Research Network (DRCR.net) investigators.

181 s Trials (CATT) and the Diabetic Retinopathy Clinical Research Network (DRCR.net).

182 s Trials (CATT) and the Diabetic Retinopathy Clinical Research Network (DRCR.net).

183 an Ministry of Heath, Fonds NutsOhra, and UK Clinical Research Network (UKCRN).

184 , Lung, and Blood Institute-sponsored Asthma Clinical Research Network and AsthmaNet.

185 Observations: Among 8 Diabetic Retinopathy Clinical Research Network clinical trials conducted from

186 opical antibiotics from Diabetic Retinopathy Clinical Research Network clinical trials.

187 year follow-up from the Diabetic Retinopathy Clinical Research Network Comparative Effectiveness Tria

188 We used Asthma Clinical Research Network data to determine the impact o

189 ence of DME on OCT used Diabetic Retinopathy Clinical Research Network eligibility criteria threshold

190 cored using the Nonalcoholic Steatohepatitis Clinical Research Network histological scoring system.

191 The Diabetic Retinopathy Clinical Research Network Protocol S randomized clinical

192 t hoc analyses from the Diabetic Retinopathy Clinical Research Network randomized clinical trial comp

193 was conducted within a Diabetic Retinopathy Clinical Research Network randomized clinical trial.

194 NAFLD from the Nonalcoholic Steatohepatitis Clinical Research Network Scoring System) from October 2

195 ccording to the Nonalcoholic Steatohepatitis Clinical Research Network scoring system).

196 s stage and the Nonalcoholic Steatohepatitis Clinical Research Network system for portal inflammation

197 We used the NASH Clinical Research Network system to score the histology.

198 llel-group trial by the Diabetic Retinopathy Clinical Research Network testing bevacizumab, ranibizum

199 652 subjects previously enrolled in 2 Asthma Clinical Research Network trials.

200 r treatment arms of the Diabetic Retinopathy Clinical Research Network's Protocol I study were used t

201 search Institute's National Patient-Centered Clinical Research Network, called the ADAPTABLE (Aspirin

202 ofi-Aventis, Pfizer, Janssen, Astellas, NIHR Clinical Research Network, Swiss Group for Clinical Canc

203 ational Institutes of Health's Rare Diseases Clinical Research Network, which consists of expert cent

204 biopsy-confirmed NAFLD enrolled in the NASH Clinical Research Network.

205 betes and Digestive and Kidney Diseases NASH Clinical Research Network.

206 National Institutes of Health Rare Diseases Clinical Research Network.

207 and Blood Institute-sponsored Heart Failure Clinical Research Network.

208 d in the Nonalcoholic Steatohepatitis (NASH) Clinical Research Network.

209 als, establish collaborative preclinical and clinical research networks in fibrotic lung disease, and

210 Despite its use in clinical research, no studies on the imaging properties

211 is high in blacks, highlighting the need for clinical research of antiplatelet agents in this populat

212 ck disease progression is a major problem in clinical research of chronic neurological disorders.

213 blished in an effort to facilitate basic and clinical research of human inherited eye disease.

214 ultimately led to the development and to the clinical research of novel embolic protection devices.

215 have seen translation to higher species and clinical research of previously inaccessible targets, wh

216 ion to enabling efficient and cost-effective clinical research on a range of neurological pathologies

217 n be used in clinical practice and in future clinical research on atopic dermatitis.

218 fy several important perspectives for future clinical research on candidate selected regions that inc

219 lopment discerned in this effort are guiding clinical research on disorders with an immune cell base.

220 o provide an overview of the updated ongoing clinical research on embolic protection devices and pres

221 Clinical research on HIFU therapy for leiomyomas began i

222 Clinical research on HIFU therapy for localized PC began

223 cessary to inform public health policies and clinical research on iodine nutrition, particularly the

224 In this review article, preclinical and clinical research on PEG-b-PLA micelles and PLGA-b-PEG-b

225 derrepresentation of minorities in published clinical research on pulmonary diseases.

226 Meanwhile, clinical research on RBC transfusion is considering both

227 rspective, David Hyman and coauthors discuss clinical research on the application of genomic informat

228 gists; 2) an increase in funded training and clinical research opportunities, including reintroductio

229 pants, investigators, sponsor personnel, and clinical research organisation staff who analysed the da

230 Study teams from the sponsor and clinical research organisation, investigators, and patie

231 erated randomisation schedule, prepared by a clinical research organisation.

232 rs) from 17 sites (hospitals and independent clinical research organisations) in the Netherlands and

233 uctuations, our procedure may translate into clinical research particularly to investigate potentiall

234 by the Massachusetts General Hospital (MGH) Clinical Research Pharmacy with a permuted-block algorit

235 entified from linkages to the United Kingdom Clinical Research Practice Datalink in England and the P

236 US Department of Defense Infectious Disease Clinical Research Program and US National Institutes of

237 This unique clinical research program will facilitate future studies

238 The Malawi Liverpool Wellcome Trust Clinical Research Programme (MLW) has routinely collecte

239 The Malawi-Liverpool-Wellcome Trust Clinical Research Programme has done sentinel surveillan

240 cousin of hearing science, with low-quality clinical research providing unreliable estimates of effe

241 ns for Diabetic Retinopathy as 91 answerable clinical research questions about intervention effective

242 Among the final list of 106 clinical research questions, 22 questions met our defini

243 published up to March 2016 to high-priority clinical research questions.

244 Language used to describe clinical research represents a powerful opportunity to e

245 broadly, to examine the implications of the clinical research response mounted.

246 Existing models of clinical research seem increasingly unlikely to produce

247 one of four dose groups at SGS Life Sciences Clinical Research Services, Belgium.

248 Future clinical research should focus on large placebo-controll

249 articipants were enrolled in 6 United States clinical research sites affiliated with the HVTN between

250 12 clinical research sites of the HIV Prevention Trials Net

251 deletion, recruited through 12 international clinical research sites, were included.

252 The treating physician, clinical research staff, and participants were masked to

253 By today's clinical research standards, Kuhn's method of unfettered

254 Further clinical research studies are needed to validate biomark

255 core domains that should be assessed in all clinical research studies evaluating acute respiratory f

256 easures that are essential to include in all clinical research studies evaluating ARF survivors after

257 holders agree are essential to assess in all clinical research studies evaluating the outcomes of acu

258 ysis of CSR junctions is useful in basic and clinical research studies of B cell functions.

259 Clinical research studies of fasting with robust designs

260 and variability could be used effectively in clinical research studies, particularly in the evaluatio

261 epair tissue that has primarily been used in clinical research studies.

262 l tool for individual patient management and clinical research studies.

263 cluding 418 participants was conducted at 49 clinical research study sites from January 27, 2014, to

264 Preclinical and clinical research suggest that hypofractionation-fewer t

265 Several lines of preclinical and clinical research suggest that the OT system may play a

266 Animal studies and recent clinical research suggests that B. caapi preparations sh

267 understood, growing evidence from basic and clinical research suggests that fluctuations in ovarian

268 major depressive disorder (MDD), and recent clinical research suggests that ketamine, an antagonist

269 Cross-sectional epidemiological and clinical research suggests that lower cardiac index is a

270 Clinical research suggests that paediatric liver disease

271 Council, Swedish Heart and Lung Foundation, Clinical Research Support at Uppsala University, German

272 However, clinical research supporting the classification system i

273 e for the criteria (clinical care, basic and clinical research, surveillance, or quality improvement

274 giogenic and stem cell therapies, review the clinical research that has been done, summarize the less

275 hms and dedicated fusion databases and (iii) clinical research that seeks to either therapeutically t

276 standardized methods for the conduct of TBM clinical research that were drafted at an international

277 will have important applications for future clinical research, the identification of disease modifie

278 tyle network is acquired from laboratory and clinical research, the strategic and precise role of lif

279 t risk of pancreatic cancer is restricted to clinical research; the incidence of familial pancreatic

280 A priority for fundamental and clinical research, therefore, is to decipher the functio

281 on that preclinical research will align with clinical research to build a common framework of compara

282 P. aeruginosa Basic, preclinical, and early clinical research to develop vaccines for other types of

283 This year's Lasker-DeBakey Prize for Clinical Research to Douglas Lowy and John Schiller cele

284 We also include recommendations for future clinical research to fulfill quality aims within cardiov

285 the brain, has been used in preclinical and clinical research to investigate neuroinflammation in vi

286 termine if sex bias exists in human surgical clinical research, to determine if data are reported and

287 production to be made available for use as a clinical research tool and further evaluation as a candi

288 the recipient of a British Heart Foundation Clinical Research Training Fellowship (FS/14/48/30828).

289 Wellcome Trust Clinical Research Training Fellowship.

290 ars, BMI 20-35 kg/m(2)) from a database of a clinical research unit in the UK.

291 h meeting organized by the Oxford University Clinical Research Unit in Vietnam.

292 glucose regulation while they resided on our clinical research unit.

293 th Africa, UK, and USA (including hospitals, clinical research units, and private offices).

294 ty of phosphoproteomics to a wide variety of clinical research, where sample material is highly limit

295 ther integration of animal model studies and clinical research will define novel therapeutic targets

296 avancin continues to be supported by ongoing clinical research with the recent launch of the Telavanc

297 m of amifostine cytoprotection and encourage clinical research with this agent for the treatment of p

298 er, such studies are maturing and may foster clinical research, with opportunities to enhance the sur

299 s, which might slow down creative biomedical clinical research without necessarily restricting abuses

300 Furthermore, basic and clinical research would clarify the underlying mechanism