ライフサイエンスコーパス: clonal cell

1 on of IL-2 increases the numbers of dividing clonal cells.

2 odorant receptors may be expressed by these clonal cells.

3 sity to homozygosity for the MPL mutation in clonal cells.

4 media, both primary keratocytes and selected clonal cells aggregated to form attachment-independent s

5 In this study, we use live cell imaging and clonal cell analyses to evaluate the fidelity of chromos

6 ribution of responses within a population of clonal cells, and the number of outliers.

7 Clonal cells are genetically homogenous and derived from

8 The median percentage of clonal cells as determined by ASO-PCR was 0.02 for MGUS,

9 combinant receptors selectively expressed in clonal cells as the dependent variable in QSAR presents

10 combinant receptors selectively expressed in clonal cells as the dependent variable in three-dimensio

11 This study shows that, by using ASO-PCR, clonal cells can be found at very low levels in the bloo

12 Nevertheless the clonal cells compete successfully with normal memory CD8

13 Using clonal cell culture combined with long-term time-lapse v

14 Clonal cell culture is crucial for experimental protocol

15 We have established a clonal cell culture system that supports the proliferati

16 Using a clonal cell culture system, we show that SOX10 inhibits

17 ion and global histone acetylation levels in clonal cell cultures from a female RTT patient with the

18 The selected clonal cells exhibited normal karyotype and underwent re

19 acteristic of biased repertoires seen during clonal cell expansions, implying that strong T-cell resp

20 ERG lineages, indicating earlier or separate clonal cell expansions.

21 e idea that drug affinity data obtained from clonal cells expressing recombinant receptors may be sup

22 form lesions harbor mutations permissive for clonal cell growth.

23 of the c-subunit in the PTP, we generated a clonal cell, HAP1-A12, from near-haploid human cells, in

24 unit b and the OSCP in the PTP by generating clonal cells, HAP1-Deltab and HAP1-DeltaOSCP, lacking th

25 different blastomeres but is independent of clonal cell heritage and of whether the blastomere is wi

26 e different methods to detect and quantitate clonal cells, ie, immunofluorescence microscopy (IM) for

27 These results indicate that the clonal cells in MGUS differ from those in myeloma and su

28 Using time-lapse imaging of clonal cells in rat cortex over several generations, we

29 Using ASO-PCR, we were able to detect clonal cells in the blood in 13 of 16 patients with MGUS

30 However, the number of clonal cells in the blood of MGUS patients is less than

31 However, identifying clonal cells in the blood of patients with monoclonal ga

32 Clonal cells in the blood should be quantified in future

33 Posterior-localized clonal cells in the follicle cell layer of developing ov

34 % to 51%) and PCR estimates of the number of clonal cells in the peripheral blood (range, .009% to 3.

35 While the small number of circulating clonal cells is not incompatible with their proposed rol

36 Here, we use clonal cell labeling with multicolor reporters to charac

37 sion within and between functional zones and clonal cell layers.

38 zed beta-adrenergic receptors (beta-AR) in a clonal cell line (C1) immortalized from cerebral cortica

39 racteristic of terminal differentiation in a clonal cell line (clone C) of rabbit kidney intercalated

40 ntiation, we established a novel P19-derived clonal cell line (designated A404) harboring a smooth mu

41 One clonal cell line (MUTM-NEI/1) was characterized in nonpe

42 From the TM of the H-2Kb-tsA58 mouse, a clonal cell line (MUTM-NEI/1) was established.

43 yotubes within neuroblastoma X glioma hybrid clonal cell line (NG108-15) increased nPKC theta express

44 ings of human MiRP3 and Kv4.2 expressed in a clonal cell line (tsA201) reveal MiRP3 to modulate Kv4.2

45 An apoE4-expressing clonal cell line and a non-expressing clonal control cel

46 Unexpectedly, a clonal cell line contained heterogeneously sized network

47 eptides selected for their ability to bind a clonal cell line derived from hPS cells would bind early

48 n of variant alleles below 0.1% frequency in clonal cell line DNA and in cell-free plasma DNA.

49 The rat phaeochromocytoma PC12 clonal cell line expresses an O2-sensitive voltage-depen

50 Our indicator cell line, SupT1-CCR5 cells (a clonal cell line expressing CD4, CXCR4 and CCR5) provide

51 A clonal cell line expressing prorenin was generated and g

52 d populations of cells from all donors and a clonal cell line from 1 donor expressed telomerase activ

53 In opossum kidney cells, a clonal cell line in which the PTHR1 and NPT2a are endoge

54 old more galectin-3 than mucin purified from clonal cell line LS-C, which produces mucin lacking peri

55 Therefore, the 1H91 clonal cell line may provide an in vitro model for study

56 More dramatically, the anion exchanger of a clonal cell line of intercalated cells derived from the

57 A clonal cell line of rat embryonic hippocampal origin (H1

58 However, only one clonal cell line overexpressing the protein but not prev

59 ceptor internalization was investigated in a clonal cell line stably transfected with the 5-HT2A rece

60 This approach identified a clonal cell line that exhibited approximately 10-fold re

61 HL-60 A2 is a clonal cell line that is defective for sialylation and a

62 l interfering RNA against GIPC to generate a clonal cell line that is deficient in GIPC.

63 A clonal cell line was selected from cells that formed foc

64 Using a rat CNS clonal cell line with neuronal progenitor properties, we

65 se findings are the first demonstration of a clonal cell line with primitive and definitive hematopoi

66 ND7/23 cells (a dorsal root ganglion-derived clonal cell line) and rat primary cerebrocortical neuron

67 cells, cultures of N-18 cells (neuroblastoma clonal cell line) are treated for 30 min in serum-free m

68 separate lineages using a well-characterized clonal cell line, 2T3, derived from the mouse calvariae.

69 mmortalized human dorsal root ganglion (DRG) clonal cell line, HD10.6, with a tetracycline-regulatabl

70 A clonal cell line, L-S1, has been identified from transfe

71 (ix) A novel HEp-2 clonal cell line, termed IkappaBalphaDN, was generated w

72 romocytoma (PC12) cells, an oxygen-sensitive clonal cell line.

73 ne synthesis, in the pheochromocytoma (PC12) clonal cell line.

74 hotopic tumors initiated from a biphenotypic clonal cell line.

75 mal integration efficiency approached 40% of clonal cell lines (essentially 50% of infected cells), o

76 c transcription of about 4000 human genes in clonal cell lines and found that more than 300 were subj

77 of alpha4beta2 levels and responses in both clonal cell lines and midbrain neurons, and the regulati

78 We show that clonal cell lines and polyclonally activated normal T ce

79 fferently processed in neurons compared with clonal cell lines and that farnesylation does not accoun

80 ent provirus from different lymphocyte-based clonal cell lines as well as from latently infected prim

81 within as little as 1-2 weeks, and modified clonal cell lines can be derived within 2-3 weeks.

82 Long-term studies on CHO ldlr(-/-) a7 clonal cell lines carrying iBAC-S/MAR-LDLR demonstrated

83 We generated human clonal cell lines carrying the two vectors using site-sp

84 MOI of 100 or greater, however, 35 to 40% of clonal cell lines contained integrated AAV DNA.

85 h 80% of cells are infected, less than 5% of clonal cell lines contained integrated AAV DNA.

86 Clonal cell lines containing human CFTR were identified

87 d [Asp218,Asp222]Mek immunoprecipitated from clonal cell lines could phosphorylate kinase-inactive Er

88 Experimental clonal cell lines demonstrate an average of 33+/-4.4% (P

89 The CHO-K1 clonal cell lines demonstrated a wide range of luciferas

90 the growth and differentiation properties of clonal cell lines derived from 32Dcl3 which harbor myb t

91 rays to assess allele-specific expression in clonal cell lines derived from heterozygous mouse strain

92 SUIT-2 and clonal cell lines derived from it show spontaneous metas

93 Clonal cell lines derived from latent populations showed

94 Clonal cell lines derived from stable transfection with

95 Embryonic stem (ES) cells are clonal cell lines derived from the inner cell mass of th

96 is transient and viral DNA is not present in clonal cell lines derived from the transformed foci.

97 not all, tumor cells, and examination of the clonal cell lines derived from the tumor population show

98 promoter, to generate by infection 34 Jurkat clonal cell lines each containing a single integration o

99 umors, transplanted primary tumor cells, and clonal cell lines established from tumors.

100 expressed receptor mRNA, but only 14% of the clonal cell lines expressed receptor protein.

101 A431 clonal cell lines expressing non-phosphorylated dominant

102 on of stably transfected cell populations or clonal cell lines expressing specific amounts of a desir

103 First, using transduced clonal cell lines expressing varying levels of ABCG2, we

104 Clonal cell lines from four mixed cell populations were

105 or constitutively active mutants of Rac1 in clonal cell lines have established that Rac1 plays a key

106 n of NIH/3T3 cells with human L1 resulted in clonal cell lines in which L1 adhesion was consistently

107 HBX lines as well as clonal cell lines of cells transfected with 246p53 (246

108 We have developed clonal cell lines of human bronchial smooth muscle origi

109 We developed clonal cell lines of human bronchial smooth muscle origi

110 h factor-I (IGF-I) signaling, we established clonal cell lines overexpressing wild type or inactive m

111 effects of EGF on integrin function, whereas clonal cell lines overexpressing wild-type FLNa were mor

112 ciencies for the development of stable human clonal cell lines ranging from 5 x 10(-7) to 8.8 x 10(-5

113 Clonal cell lines reflect an independent choice to expre

114 Clonal cell lines representing early cardiomyocytes woul

115 e expression of temperature-sensitive p53 in clonal cell lines results in ALT-specific, transactivati

116 Analysis of multiple independent clonal cell lines revealed that expression of either Ets

117 sing RNA from proband dermal fibroblasts and clonal cell lines showed the mutant cDNA was about 15% o

118 either step is mediated by MTP, a series of clonal cell lines stably expressing apoB-53 and MTP was

119 trol of tetracycline (Tc) initially requires clonal cell lines stably expressing the tetracycline act

120 on were greater in ethanol-sensitive NIH/3T3 clonal cell lines than in their ethanol-insensitive coun

121 Clonal cell lines that contained a conserved approximate

122 h cells transfected with vector and with two clonal cell lines that each expressed different amounts

123 Clonal cell lines that overexpressed three times more Tb

124 Clonal cell lines that stably expressed HBx messenger RN

125 was inhibited by U1 anti-GFP in the various clonal cell lines was assessed by fluorescence-activated

126 The fraction of accessible sites in clonal cell lines was quantitated using restriction endo

127 Clonal cell lines were challenged with recombinant Sindb

128 Thirty-two AT6.1-12 clonal cell lines were established and the region(s) of

129 and metabolism, ADFP null and wild type (wt) clonal cell lines were established from ADFP null and wt

130 n fluorescent protein, and stably transduced clonal cell lines were generated by serial dilution in t

131 Clonal cell lines were isolated by fluorescence-activate

132 in cell spreading, several NIH-3T3- derived clonal cell lines were isolated that overexpress the bio

133 Clonal cell lines were selected with an antibiotic resis

134 xpressed with wild-type receptor, and stable clonal cell lines were selected.

135 A series of transient transfection assays in clonal cell lines which do not express ARPP-21 identifie

136 To demonstrate the technique's utility, clonal cell lines with siRNA knockdown of Coronin 1B wer

137 Using isogenic, clonal cell lines with variable copy numbers of an EGFP

138 s and the generation of edited cell pools or clonal cell lines, reducing the number of clones that ne

139 Compared with single-cell organisms or clonal cell lines, the biological environment and medica

140 -derived growth factor (PDGF) receptors, all clonal cell lines, with either type of chimera, showed s

141 e pattern of methylation is constant between clonal cell lines.

142 e [Asp218]- and [Asp218,Asp222]Mek1-infected clonal cell lines.

143 mutant overexpression approaches in various clonal cell lines.

144 n A partially rescued transgene silencing in clonal cell lines.

145 mooth muscle cells and generate a variety of clonal cell lines.

146 l kinase (JNK) activity in insulin-secreting clonal cell lines.

147 pha and beta-type mRNAs were co-expressed in clonal cell-lines.

148 Clonal cells (N18) of the mouse neuroblastoma C-1300 can

149 many of the genetic aberrations found in the clonal cells of myeloma.

150 We tested for these abnormalities in the clonal cells of WM patients.

151 ry resulted in the generation of rare, large clonal cell patches that were associated with stem cell

152 bserved intercellular heterogeneity within a clonal cell population can be mapped as dynamical states

153 A clonal cell population exhibiting a uniform vector integ

154 ity can lead to 'variations on a theme' of a clonal cell population, often with each cell within a tu

155 ry greatly within similar cells, even within clonal cell populations [1].

156 on, the uniformity of gene expression within clonal cell populations and the reproducibility of gene

157 l-to-cell variations in protein abundance in clonal cell populations are ubiquitous in living systems

158 iptome-wide analyses of allelic imbalance in clonal cell populations based on sequence polymorphisms,

159 Flo11-dependent phenotypic heterogeneity in clonal cell populations by modulating recruitment of key

160 owever, dynamic non-genetic heterogeneity of clonal cell populations continuously produces metastable

161 g boosting with different vectors, and these clonal cell populations could be detected for as long as

162 tions, both parental and single-cell-derived clonal cell populations differentiated to the chondrocyt

163 Immunostaining of clonal cell populations showed MIWC expression at the pl

164 Clonal cell populations were analyzed for deletions by u

165 mporal association of the detection of these clonal cell populations with infection and the dominance

166 These mechanisms include direct selection of clonal cell populations with the capacity to rapidly upr

167 protein 1, and Biglycan were examined within clonal cell populations, comprising either part of, or m

168 etuses (15 to 21 weeks postconception) using clonal cell populations.

169 that ParE(1) toxicity is not uniform within clonal cell populations.

170 ation doublings in the absence of hormone in clonal-cell populations, and the silent transgenes in th

171 We have analyzed clonal cell proliferation in the ventricular zone (VZ) o

172 The same clonal cells seeded at high density targeted these prote

173 ow peaks, which could be a characteristic of clonal cell selection, clonal expansion, or both.

174 contributes to the eradication of resistant clonal cell subpopulations.

175 Clonal cells that inducibly expressed caPKA enhanced the

176 also identified a minor subpopulation of non-clonal cells that were classified as metastable, pseudod

177 In all cases in which IM or FC detected clonal cells, the ASO-PCR was positive.

178 isolation of the ST3GAL5 and SLC35A2 mutant clonal cells uncover a previously unappreciated differen

179 Perhaps the clonal cells use IL-15 more effectively or are more resi

180 + blood cells in relationship to circulating clonal cells was done in 13 myeloma patients using a clo

181 h MGUS with blood involvement, the number of clonal cells was very small ( < 0.04% of the BMNCs).

182 lls with U1 ribozyme-encoding vector, stable clonal cells were selected in which the expression of al