ライフサイエンスコーパス: close

1 minate people with whom they felt personally close.

2 k1 autophosphorylates Y209 as MII draws to a close.

3 earrangements during ion channel opening and closing.

4 another domain acts like a lid, opening and closing access to the hydrophobic tunnel, which accommod

5 catalytic domain of human A3B has a tightly closed active site, and rearrangement of the surrounding

6 We find close agreement between our 'top-down' and combined 'bot

7 full-wave simulation, and predictions showed close agreement with experiment for composite materials

8 f a national monsoon mission project, showed close agreement with observations.

9 The close alignment of the circulatory and ingestion systems

10 function studies performed with structurally close analogs explain the FD44 specificity and the mecha

11 In contrast, wildtype RyR1 was closed and not activated by luminal Ca(2+) at low cytoso

12 evealed a dynamic exchange between partially closed and open conformations of the SAM-II riboswitch i

13 eipt, 3- and 6-mo follow-up), acceptability (closed and open-ended end-of-study feedback at 6 mo), an

14 hich adopts two principal conformations, one closed and the other slightly open.

15 ices when decision and action are temporally close, and that this choice effect can be dissociated fr

16 prey during the period from mouth opening to closing, and although they need thrust force to stabiliz

17 d rats showed greater number of entries into closed arms and center compared to controls and those ex

18 while discriminating signals from neurons as close as 20 mum apart, at a computational cost three ord

19 ity due to the spatial regulation of MNPs as close as possible to the MOF surface.

20 edure, designed to yield simulated tumors as close as possible to the observed ones, vary by an order

21 t decreases the force across VE-cadherin, in close association with downstream signaling [5].

22 BK/Kv were mostly closed at rest in normoxia.

23 he smart human sweating pores, the flaps can close automatically after the perspiration to keep the w

24 ockage of the nanopore with Pt metal forms a closed bipolar nanoparticle electrode whose size and sha

25 Enrolment into this cohort is closed, but patients are still being monitored for safet

26 of in situ imine formation followed by ring-closing, but support instead hydrogen-bond assisted ring

27 ntain complete SRK and SCR sequences located close by one another in the derived genomic position of

28 the ion permeation pathway of the channel is closed by a constriction of the inner pore formed by cri

29 med by Gln-4933, rather than Ile-4937 in the closed-channel structure.

30 ection in normal canines with open (n=3) and closed chest (n=5) and in a pig model with features of h

31 duced expression, and epigenetic features of closed chromatin in male germ cells, which suggests that

32 dynamic binding modes help maintain open or closed chromatin, respectively.

33 plicative intermediates including covalently closed circular DNA (cccDNA) are present.

34 pies, lies in the accumulation of covalently closed circular DNA (cccDNA) in nuclei of infected cells

35 binding, taurocholate uptake, HBV covalently closed circular DNA formation, and expression of all HBV

36 additionally includes loss of HBV covalently closed circular DNA.

37 for further evaluation in larger series and close collaboration between imaging and oncology special

38 If carefully planned for and based on a close collaboration between programme partners and manuf

39 c13 catalyzes the transit of syntaxin from a closed complex with Munc18 into the ternary SNARE comple

40 ection processes in networks operating under closed conditions.

41 hat Munc18c, like Munc18a, binds to both the closed conformation and the N-peptide of Syx4.

42 The prefusion-closed conformation of HIV-1 Env has been identified as

43 by Src homology 3 (SH3) domain, leading to a closed conformation, whereas a non-phosphorylatable S561

44 ate it is in equilibrium between "open" and "closed" conformational states.

45 n and validation of new target structures in close conjunction with the application of novel techniqu

46 ILC3s and regulatory B cells were in close connection with each other in palatine tonsils.

47 el of theory reproduce the structure and the close contact well (1.555 A at 0 K) and emphasize the si

48 We analyzed close contacts between halogens and electron-rich moieti

49 heir potential for transmitting the virus to close contacts.

50 in the darkness at ambient temperature in a closed container to simulate current storage conditions

51 This was achieved by means of close cooperation and communication between clinicians a

52 In this Progress Report we postulate a close correlation between impact - whether academic, tec

53 There was a close correspondence between the phenology of flowering

54 clinical observations was indirect, there is close correspondence to neuroanatomical data.

55 to stimulate E3 activity by stabilizing the closed E2 approximately Ub conformation.

56 and high electron affinity Co6Te8(CO)6 have closed electronic shells marked by high HOMO-LUMO gaps o

57 intensities are observed for the open versus closed Fe2O2 cores in the model compounds.

58 Y: T206F and V213Y) generates a persistently closed form of the activation gate in which the intracel

59 ic direction for applied forces to drive the closed form to the open form.

60 Closed globe injury was most frequent (23 cases), follow

61 n arresting the enzyme adenylate kinase in a closed high-energy conformation that is on-pathway for c

62 The opal5 mutant does not close in response to darkness but exhibits wild-type (WT

63 ealed that the catalytically active state is closed in a highly strained asymmetric conformation.

64 er loss and carbon dioxide uptake occur, are closed in response to drought by the phytohormone abscis

65 measuring KcsA's activation gate opening and closing in conditions that promote or halt C-type inacti

66 duced necroptosis, and delayed culture wound closing in three types of immortalized cancer cell lines

67 extracellular mouth of the ion pore remains closed, indicating that local movements of the transmemb

68 A close inspection of the calculated unoccupied molecular

69 The close inter-relationship of capillaries and the renal ep

70 ve shown that MSC tumour residence and their close interactions with inflammatory factors are importa

71 Moreover, lytic virus growth requires a close interplay between fibroblasts and keratinocytes.

72 For instance, Closed-J sacrifices thermal stability of the Dumbbell st

73 ited States may have unequal availability of close kin and that this gap in availability will widen i

74 at the surrounding epithelial cells directly closed lesions up to six cells.

75 -state transition from an open-unliganded to closed-liganded state during the transport cycle.

76 We do so by taking a close look not only at how sign has been studied over th

77 and was lower under bolus resuscitation than closed loop at 20 minutes (bolus resuscitation: 57 +/- 2

78 odal-line semimetals forms a one-dimensional closed loop.

79 citation: 19.3 +/- 2 mm Hg, decision assist, closed loop: 24 +/- 0.4 mm Hg; p < 0.05) and hemoglobin

80 inutes (bolus resuscitation: 57 +/- 2 mm Hg, closed loop: 69 +/- 4 mm Hg; p = 0.036).

81 in which ligand binding to the lectin domain closes loop 83-89 around the Ca(2+) coordination site, e

82 As an exception, training on closed-loop (CL) sensorimotor interfaces, such as action

83 insulin pumps, continuous glucose monitors, closed-loop and artificial pancreas systems) have been t

84 namics and in neuro-engineering to implement closed-loop applications.

85 involvement in human upright walking with a closed-loop BCI has not been investigated.

86 Here a closed-loop cavitation controlling paradigm that sustain

87 get glucose range was 59.8% (SD 18.7) in the closed-loop group and 38.1% (16.7) in the control group

88 to investigate whether day-and-night hybrid closed-loop insulin delivery can improve glucose control

89 mulation (e.g., retinal prostheses), and for closed-loop neural stimulation at a much larger scale th

90 Inducing this spatiotemporal dynamic using closed-loop optogenetic stimulation is sufficient to inc

91 One participant withdrew during the first closed-loop period because of dissatisfaction with study

92 Here we present a closed-loop real-time imaging strategy that automaticall

93 ificantly reducing faradaic energy losses in closed-loop RED systems.

94 We used closed-loop SPW-R detection at goal locations to trigger

95 ied that is now used to investigate adaptive closed-loop stimulation in first studies.

96 To further explore the translation of closed-loop TES for treatment of epilepsy, we show here

97 ow here for the first time that unsupervised closed-loop TES in rats can consistently interrupt seizu

98 n" mitotic arrest deficient 2 (O-MAD2) into "closed" MAD2 (C-MAD2).

99 ations of bis(vinyl boronate esters) or ring-closing metathesis reactions followed by complexation wi

100 Iron(III)-catalyzed carbonyl-olefin ring-closing metathesis represents a new approach toward the

101 A ring-closing metathesis served for construction of the seven-

102 A highly efficient, Z-selective ring-closing metathesis system for the formation of macrocycl

103 r, and the lactone moiety was formed by ring-closing metathesis.

104 h the E,Z-diene part, an ester-tethered ring-closing metathesis/base-induced eliminative ring opening

105 Indeed, an RC DNA species with a covalently closed minus strand but an open plus strand (closed minu

106 closed minus strand but an open plus strand (closed minus-strand RC DNA [cM-RC DNA]) was detected by

107 HPVG requires a close monitoring of the clinical status, which is crucia

108 Close monitoring of the implementation of the Dutch nati

109 ve access to multiple cancer treatments with close monitoring while receiving regimens associated wit

110 There should be close monitoring, for the increased risk of neurocogniti

111 n which its open Ca(2+)-activated C-lobe and closed N-lobe cooperate to recognize a mixed alpha/310 h

112 Whereas SR-BI(-/-) embryos with closed neural tubes (nSR-BI(-/-)) had high levels of rea

113 ucleotide binding domains drives opening and closing of the MacB periplasmic domains via concerted mo

114 g-opening of cyclobutene, electrocyclic ring-closing of Z-hexatriene, the [1,5]-H shift in Z-pentadie

115 arlo method and demonstrate pathways for the closed-open conformational transition in both directions

116 r, which allows the trimer to adopt either a closed or an open conformation.

117 nt in solution, where Dcp2 adopts an open, a closed, or a catalytically active state.

118 t superlattice structures, such as hexagonal close-packed lattices.

119 t the high-pressure synthesis of a hexagonal close-packed phase of the prototypical high-entropy allo

120 a: see text], a uniformity similar to random close packing and early universe fluctuations, but with

121 e-centred-cubic (fcc) structure to hexagonal-close-packing (hcp) structure in the prototype CoCrFeMnN

122 ucture composed of face-centered cubic (fcc) close-packing of near-spherical C60 superatoms.

123 Our revised road map emphazises close parallels of terminal mTEC development with that o

124 inquity, the tendency of rodents to maintain close physical proximity.

125 in complex with cholesterol, which sits in a closed pocket at the centre of the lipocalin barrel.

126 ibility of each craniofacial articulation to close prematurely, we used a network model of the skull

127 e in chain prenylated (cPta) and one in ring-closed prenylated pterocarpans (rPta), as characterized

128 oth adjuvants and antigens should be kept in close proximity (i.e. physically linked) to ensure deliv

129 , specific proteins tether the organelles in close proximity and mediate the nonvesicular trafficking

130 on, but without necessarily being located in close proximity to each other.

131 cularly in communities where animals live in close proximity to humans.

132 all number of pixels on the detector, are in close proximity to other particles or suffer from backgr

133 n nutrient-rich fat cells, GRASP clusters in close proximity to the apical side of lipid droplets (LD

134 and alphaIIb is the synergy site located in close proximity to the RGD motif.

135 leaving group that tethers fluorochromes in close proximity, also positioning them distant from the

136 At close proximity, light-matter interaction between Au NBs

137 that have the transferring hydrogen atoms in close proximity, such as ortho-tetrachlorobenzoquinone o

138 hing effect of the gold nanoparticle even at close proximity.

139 thioredoxin-binding and kinase domains into close proximity.

140 ure that brings UAS1 and UAS2 into spatially close proximity.

141 hes can complement the traditional method of close reading in detecting trends of continuity and chan

142 The genome also revealed the close relationship between CLI2509 and Streptomyces sp.

143 The find reflects a close relationship between the two Triassic entomofaunas

144 S rRNA percent, and 5S-18S rRNA ratio, using close relationship between volume percent of primary gro

145 Phylogenetic analysis supported close relationships among HCV sequences from the four ma

146 n, low social isolation and loneliness, more close relationships, better self-rated health, fewer chr

147 owers of Cardamine hirsuta from those of its close relative Arabidopsis (Arabidopsis thaliana), and a

148 igin and early history of therians and their close relatives (i.e., cladotherians) remains surprising

149 Females with fewer close relatives were more isolated, and the more time ma

150 ns, an antibiotic that kills producer cells' close relatives.

151 autophagy in the T. gondii parasite and its close relatives.

152 data of secreted adiponectin yielded a very close resemblance between the simulations and experiment

153 ature of the rate-limiting step and provided close results for the reaction barriers of the two react

154 enic species of Batrachochytrium to those of close saprophytic relatives reveals that pathogenicity i

155 Bioinformatic analysis revealed a close sequence relationship between PBP 3 and Staphyloco

156 in the transient regime, we derive a reduced closed set of equations for population-level quantities

157 originates from a fine interplay between the closed-shell nature of the d states and relativistic eff

158 ius, and the inner is that of the underlying closed-shell orbital.

159 This close similarity extended to the associated secondary ki

160 Based on DD connectivity, we illustrate the close similarity, and possible homology, between hippoca

161 obviate many of these issues, and provide a close simulation of smoking tobacco cigarettes.

162 When these bacterial species were placed in close spatial proximity, we observed an initial increase

163 channel function by locking channels into a closed state and that endogenous CFTR in HBEs is affecte

164 ion of the HIV-1 Env trimer to its prefusion-closed state as this state is recognized by most broadly

165 a flip in the asymmetry while remaining in a closed state for the second hydrolysis.

166 disrupts the characteristic long interburst closed state of reconstituted KirBac1.1 in giant liposom

167 to form the fully collapsed metabolite-bound closed state of the SAM-I riboswitch.

168 cted pore; this is likely to correspond to a closed state, because a CaCC with a single Ca(2+) occupa

169 perturbing uS7-eIF2alpha interaction in the closed state, confer the opposite phenotypes of hyperacc

170 e dynamics and shorten the dwell time in the closed state.

171 gating via stability of a novel inactivated closed state.

172 atomistic molecular dynamics studies of the closed-state, non-conducting C1C2 structure and protonat

173 e ability of RbmA to switch between open and closed states is important for V. cholerae biofilm forma

174 D411 with lower S4 residues stabilizes early closed states of the channel, and that disruption of the

175 d F57Bpa KCNE1 were cross-linked in open and closed states, respectively, which suggests that their a

176 Guard cells shrink and close stomatal pores when air humidity decreases (i.e. w

177 cing Microcystis aeruginosa PCC 7806 and its close strain, the nonproducing Microcystis aeruginosa PC

178 ammation in vivo Comparing AGN 211377 with a close structural congener lacking EP1 antagonism (AGN 19

179 t self-assembly to generate highly intricate closed supramolecular architectures, ranging from self-a

180 In a closed system, the dimerization rate is first order in t

181 reasing substrate fractions and is valid for closed systems.

182 relatedness between conditions occurring in close temporal proximity - will favor populations that w

183 nts to be applied to at-risk individuals, in close temporal proximity to environmental impacts known

184 d offers an inhibition of enzymatic activity close the 50% in apple extracts.

185 using permeable nitinol cardiac occluders to close the access ports, were common but acceptable in th

186 for the emission source that is required to close the Amazon CH4 budget.

187 Work to close the gap in the care cascade by race is imperative,

188 ers to the sea surface in the Southern Ocean closes the global overturning circulation and is fundame

189 ing swallowing based on targets required for closing the hyo-laryngeal area for safe swallowing.

190 A standardized procedure of closing the midline laparotomy by using a "small steps"

191 All ABA-deficient lines closed their stomata rapidly and extensively in response

192 To close this gap, we have significantly expanded the datab

193 To close this gap, we now report transient kinetics and pro

194 levels of the pore conductance and two dwell closed times of the pore were found.

195 configuration at the low temperature nearly close to 0 K, and their configuration and diameter prope

196 overall relative absolute average deviation close to 0.14% for the 15,298 data points examined durin

197 The GSI probability density function peaked close to 1 in early infection and 0 around two years pos

198 in 0.93V of cell voltage and a power density close to 1.237mWcm(-2).

199 y (SRA) with no apparent defects in crown is close to 1.3%.

200 complex gene-environmental disease affecting close to 10% of the US population.

201 liver and a higher median number of cycles (close to 12).

202 the oxygen (O) 1s peak, and a Zn:O intensity close to 1:1.

203 lignan amounts in commercial olive oils was close to 2mg/L.

204 es to increase the stored energy by a factor close to 3, on account of the high pressure shift of the

205 band oscillation seen in mice at frequencies close to 60 Hz.

206 The absorption process of an emitter close to a plasmonic antenna is enhanced due to strong l

207 s while maintaining an abdominal temperature close to ambient.

208 n is particularly weak, the network operates close to an instability leading to unbounded cortical ac

209 ns fail more frequently because they operate close to budgetary boundaries, in turn because they cons

210 egions, whereas it is significantly enhanced close to cultivated zones.

211 hip hospital would retain correct management close to current levels at 37%.

212 t concentrations of PAHs and PCBs were found close to densely populated and industrialized regions, i

213 insic local interactions between amino acids close to each other in the protein sequence.

214 o other people who in turn were reciprocally close to each other was associated with a lower risk of

215 Earth's core, the outer core composition is close to eutectic in most regions resulting in a sharp i

216 39)Pu atom ratio of 0.293 +/- 0.028 we found close to FDNPP.

217 n this large population-based cohort, living close to heavy traffic was associated with a higher inci

218 pleiotropic cytokine, which is structurally close to IL-2 and shares with it the IL-2 beta and gamma

219 cal history, leading to water being retained close to its surface, and thus creating conditions condu

220 ion of the sigmoid on a log-log plot is very close to linear, allowing the unknown endogenous concent

221 frequency of the slower atria after ablation close to main interatrial conduction fascicles (P=0.035)

222 effects, with a reversal t1/2 > 6 hours and close to maximal effects that remained for at least 5 ho

223 ding HRs in the postintervention period were close to null.

224 proposed algorithms to arrive at optimal or close to optimal solutions in significantly lower number

225 ccurred in apical nucleation centers, either close to or in association with the apical surface.

226 for the neutral versus anionic quenchers and close to predicted values.

227 with H-H distances of about 1.1 A, which are close to predictions for solid atomic metallic hydrogen

228 atients and occurred at the margins of EMPD, close to previous biopsy sites.

229 owth factor evokes transient oxidation on or close to RAB5+/ early endosome antigen 1- endosomes.

230 n live actors perform behaviors perceptually close to real life and possibly really experienced by th

231 emographics with fine spatial resolution, in close to real time.

232 This possibility is now close to reality due to a recent discovery of the adapti

233 induced pluripotent stem cells is at present close to reality, and we are currently awaiting the firs

234 c plasma (CAP) devices with ion temperatures close to room temperature.

235 ed on the Roche map satisfies (ii) and comes close to satisfying (iii).

236 expanded oxide rows with a lattice constant close to that of alpha-PtO2, either assembling into spok

237 m internal standard (OIS) at a concentration close to that of the analyte significantly improved the

238 ls exposed to chronic salt intake to a level close to that reported for human' diet since weaning lea

239 on a broad region of 1000 square kilometers close to the 50-kilometer Ernutet crater.

240 n of the tertiary contacts among the regions close to the active site in the first step of unfolding,

241 (Ser-20, Thr-22, Thr-182, and Thr-240) were close to the active site, indicating their possible role

242 ein ataxin-3 carries a polyglutamine stretch close to the C-terminus that triggers a neurodegenerativ

243 elevated concentration of secretory vesicles close to the cell membrane.

244 ate that for RBCs entering the capillary bed close to the cortical surface (< 400 mum) the largest pr

245 online product analysis, we have found that close to the Cu2O-CuO phase transition there is a boost

246 dimension of the samples are often below or close to the diffraction limit of the probe light.

247 is less likely to be disrupted by a mutation close to the distal ends.

248 DNA is strongly polar, favouring correction close to the DSB end.

249 our occasions, outside the workplace, and as close to the end of a shift as possible.

250 Si) = 5.701 x 10(-7) mol mol(-1) estimate is close to the expected one and is given with a standard u

251 nance frequency decreases until getting very close to the first resonance frequency.

252 is RNA shows guanosine G40 and adenosine A32 close to the G53-U54 cleavage site.

253 For instance, tooth surfaces close to the gingival sulcus contact serum proteins that

254 , i.e., 1.2 J cm(-3) , even at a temperature close to the glass transition temperature of polymer (i.

255 factor and a staggered magnetization that is close to the ground-state value.

256 ement between all pairs of nodes, and rather close to the highest levels structurally compatible with

257 f a slowly drifting complex convective cloud close to the highest regions at 17 km altitude.

258 (Thr(304)), adjacent to conserved Ser, comes close to the HMBPP diphosphate, whereas double mutation

259 C-H bond to be functionalized by placing it close to the iron-oxo haem complex.

260 harge density of 1003 microC m(-2), which is close to the limit of dielectric breakdown, is attained.

261 A hydration depletion down to 45%, which is close to the minimum hydration found in commercially ava

262 e NMR time scale, while tumbling was slow or close to the NMR time scale depending on the position an

263 l, adjusted ORs for barium and aluminum were close to the null, whereas associations with titanium, a

264 AMR system, the uniform distribution is very close to the optimized design.

265 mitophily by approximately 80 million years, close to the origin of termite eusociality.

266 ational equilibrium of the beta3-alpha3 loop close to the phosphorylation site.

267 reticulum via Ca(2+) release channels placed close to the physiological target.

268 icon photonics, and its noise performance is close to the quantum limit.

269 acrauchenia as sister to Perissodactyla, but close to the radiation of major lineages within Laurasia

270 nt neurons superimposed upon that of neurons close to the recording electrode.

271 The accuracy on test sets is close to the result using a central processing unit.

272 ion speed of a multi-layer AMR case was very close to the single-layer configuration.

273 onsumption and facilitates solution delivery close to the SiPM to increase the detection efficiency.

274 produced in the hemizygous condition falling close to the threshold required for switching to IgE pro

275 ned for five of the designs and each is very close to their corresponding computational model.

276 yze phosphodiester bond hydrolysis within or close to their DNA target sites, they form different oli

277 ause EndMT mainly occurs in the microvessels close to these cells, and because megakaryocyte-derived

278 g and nucleic acid aptamer recognition comes close to this ideal due to the ease of multiplexing, wit

279 xposed to kitchen grime with values that are close to those reported for the octanol/air partition co

280 nce ratios for the majority of elements were close to unity providing evidence that indoor metal-bear

281 r hunter-gatherers from the Baltics, who are close to Western hunter-gatherers [8, 9].

282 in B, cell-generated frequency noise dropped close to zero with the first spectra acquired 7 minutes

283 glet-triplet energy gap (exchange energy) is close to zero, so that rapid interconversion is possible

284 cognize that current sanitation gaps must be closed to better serve those without access to safely ma

285 Trial registry (ISRCTN07742377), and is now closed to patient entry.

286 s a transition intermediate where loop 83-89 closes to engage Ca(2+) and mannose without triggering a

287 support instead hydrogen-bond assisted ring-closing to prodrugs.

288 The hormone's closed-to-open transition is foreshadowed by segmental f

289 andom samples (85% versus 88% versus 93% for closed tunnel EVH, open tunnel EVH, and open vein harves

290 t has remained unclear whether the requisite close tunneling distance occurs through an unusual groun

291 ed from an open "W"-shaped conformation to a closed "U"-shaped form.

292 Pathological tumor vessels were closed using particles filling the entire vascular tumor

293 omparison with concentrations obtained using closed vessel microwave digestion was also realized.

294 as off surface matrix was integrated in very close vicinity of the electrode surface.

295 ng the association of MAPK1 with open versus closed vinculin, we demonstrate that MAPK1 exhibits pref

296 Radical prostatectomy centres that closed were more likely to be located in areas with stro

297 Nevertheless, we close with an exploration of concatenating multiple elas

298 In order to help further the field, we close with loosely defined design rules that are at the

299 range of motion of the activation gate, from closed with its orifice fully occluded to open with an o

300 ications, and the various unsolved problems, closing with a perspective on the prospects and broader