ライフサイエンスコーパス: closure

1 M, promoting both Cdt1 ejection and MCM ring closure.

2 anspiration, and severe slowdown of stomatal closure.

3 iological pathways that contribute to palate closure.

4 omes, and pregnancy after successful fistula closure.

5 he study, we performed left atrial appendage closure.

6 odermal lineages until or beyond neural tube closure.

7 tured surgical valve paravalvular leak (PVL) closure.

8 tinct and essential roles during neural tube closure.

9 , revealing how Ca(2+) prevents binding site closure.

10 way in which calcium regulates plasmodesmal closure.

11 rated, whereas HIF1alpha shRNA delayed wound closure.

12 lective nitrogen functionalization, and ring closure.

13 n accelerating wound reepithelialization and closure.

14 ion occurred in 29 patients (6.6%) after PFO closure.

15 ectocervix (ECX) significantly delayed wound closure.

16 tins governs ciliogenesis during neural tube closure.

17 r to snow melt, which preceded forest canopy closure.

18 monthly until week 20 or occurrence of wound closure.

19 exencephaly, a severe defect in neural tube closure.

20 y of the intermediate aperture shapes during closure.

21 e embryo as a prerequisite for successful NT closure.

22 min E to the mouse embryo during neural tube closure.

23 c vitamin E uptake during murine neural tube closure.

24 tion of reactive oxygen species and stomatal closure.

25 erone function of Hsp90alpha in normal wound closure.

26 olished the effect of PVI treatment on wound closure.

27 (cNCC) mesenchyme is required for upper lip closure.

28 ack dispersal to Australasia after the Jet's closure.

29 ) occurred in 205 subjects who underwent PFO closure.

30 2+) and Ax culminated in target binding site closure.

31 tabolic processes at the time of neural tube closure.

32 cell emergence-based migration and local gap closure.

33 unanswered questions and suffer from lack of closure.

34 eleton is required for dark-induced stomatal closure.

35 ntinuously to age 15 months, death, or study closure.

36 omoting root lengthening, widening or apical closure.

37 distal right internal mammary artery device closure.

38 isms of cavitation formation during the claw closure.

39 ing pivot joints that articulate during ring closure.

40 te immune contributor to IL-10-induced wound closure.

41 inates the ability of ATP to induce stomatal closure.

42 ural plate midline and defective neural tube closure.

43 ng tissue repair, resulting in delayed wound closure.

44 equired for optimal intestinal mucosal wound closure.

45 f approaches to prevent premature diagnostic closure.

46 alpha as a potential driver for normal wound closure.

47 vents that culminates in target binding site closure.

48 nses such as callose deposition and stomatal closure.

49 who were on-study and in remission at study closure, 16 patients had not received any new treatment

50 s no difference in responder rate in the PFO closure (45 of 117) versus control (33 of 103) groups.

51 orbidity and mortality associated with early closure (8-13 days) of a temporary stoma compared with s

52 y (12.2 vs 12.2; P = 0.99) and rate of stoma closure (80.1% vs 77.3%; P = 0.53) between groups.

53 ns of the impacts of Central American Seaway closure a strengthened AMOC with a global climate signat

54 Simulations show that during claw closure, a high velocity jet forms, inducing vortex roll

55 rary stoma compared with standard procedure (closure after > 12 weeks) after rectal resection for can

56 in the development of thrombosis and abrupt closure after angioplasty is well recognized.

57 The energy-releasing, VHF-to-DHA, ring closures also occur in a stepwise manner and are systema

58 k and may contribute to premature diagnostic closure, an important cause of diagnostic errors.

59 ibranch loop initiation, AU/GU internal loop closure and AU/GU helix end parameters were particularly

60 cursor to collective cell migration in wound closure and cancer metastasis, respectively.

61 ameters in different subtypes of acute angle closure and compared to fellow eyes of AAC and PACS eyes

62 esection, 30-day readmissions, and ileostomy closure and for short-term outcomes.

63 Here, we show that S. aureus inhibits wound closure and induces miR-15b-5p in acute human and porcin

64 e long-lasting effects in promoting stomatal closure and inducing the expression of stress-responsive

65 s Mal(2-) efflux during ABA-induced stomatal closure and its activity depends on phosphorylation.

66 ing, acts in guard cells to promote stomatal closure and reduce water loss in response to water defic

67 has been shown to effectively promote wound closure and reduce wound-related infections.

68 Plants employ stomatal closure and reduced growth to avoid water deficiency dam

69 ical objects that do not require a classical closure and so naturally capture the topological ambigui

70 at ABA-increased ROS is followed by stomatal closure and that both responses are blocked by inhibitor

71 h the VPD-induced passive hydraulic stomatal closure and the stomatal VPD regulation of ABA-deficient

72 agement from ZO-1 is critical for GJ channel closure and transitioning GJ channels for endocytosis.

73 movements contribute to laryngeal vestibule closure and upper oesophageal sphincter opening during s

74 streams towards the sites of dorsal amniotic closure and ventral thoracic wall formation.

75 oposed for humpback whales, where valve open/closure and vocal fold oscillation is passively driven b

76 The time scale of stomatal closure and xylem cavitation during plant dehydration, a

77 eaf) declines, which contributes to stomatal closure and, eventually, to leaf death.

78 s, both on local (extracellular gate opening/closure) and global (transition between outward-facing a

79 e times required for channel freezing (valve closure) and thawing (valve opening) were measured.

80 aningful ways that facilitate continuity and closure, and ease emotional trauma.

81 tered, loss of PGX3 prevents smooth stomatal closure, and overexpression of PGX3 accelerates stomatal

82 dermal-epidermal separation, improved wound closure, and reduced blister formation.

83 to megabase-scale path reorganizations, gap closures, and localization of previously orphaned sequen

84 The Tethys closure appears not to have been influential, however we

85 Thus, the loss of domain closure appears to be solely due to loss of binding.

86 isk factors for cardiac erosion after device closure are not yet clear.

87 e noon in marathon-affected areas (when road closures are likely) had longer scene-to-hospital transp

88 organelle expansion and ultimately organelle closure around a particular cargo.

89 s; (ii) the ability of PITPalpha to initiate closure around the PtdCho ligand is accompanied by loss

90 icular contraction ablation, an aortic valve closure artifact is observed in up to one third of cases

91 n the initiation involving a transient clamp closure as a prerequisite for DNA melting.

92 dy examined the efficacy of percutaneous PFO closure as a therapy for migraine with or without aura.

93 p90alpha-Delta mutant protein promoted wound closure as effectively as the full-length wild-type Hsp9

94 , length of hospital stay, and rate of stoma closure at 6 months.

95 tients who underwent percutaneous mitral PVL closure at Mayo Clinic, Rochester, MN, between January 2

96 treat, was proportion of patients with wound closure at week 20.

97 echanical mechanisms involved in neural tube closure, based on studies of various vertebrate species,

98 nstraint, predisposing some articulations to closure, both in normal and pathological development, al

99 iating and maintaining the asymmetry of ring closure but the role of possible asymmetry in the materi

100 is the key signal in stress-induced stomatal closure, but ABA as an early xylem-delivered signal is s

101 ta (TGFbeta) signalling is essential for VBW closure, but the responding cells are not known.

102 uced epithelial cell proliferation and wound closure by activating epithelial pro-proliferative pathw

103 fibroblasts in orchestrating ventral midline closure by mediating the response to the TGFbeta gradien

104 de that topical mevastatin accelerates wound closure by promoting epithelialization via multiple mech

105 stroke was lower among those assigned to PFO closure combined with antiplatelet therapy than among th

106 Drosophila dorsal closure (DC), a morphogenetic process in which an extrae

107 zer and along the axial midline, neural tube closure defects (NTDs) arose and dorsal extension was co

108 man congenital disorders such as neural tube closure defects.

109 in early embryonic lethality and neural tube closure defects.

110 onitor the safety of an implantable vascular-closure device that had a suspected association with inc

111 analysis of the safety of the Mynx vascular-closure device, as compared with alternative approved va

112 among recipients of an implantable vascular-closure device, with initial alerts occurring within the

113 complication than were alternative vascular-closure devices (absolute risk, 1.2% vs. 0.8%; relative

114 current transcatheter left atrial appendage closure devices and review the results associated with l

115 Purpose-built closure devices are in development that may simplify the

116 compared with alternative approved vascular-closure devices, with data from the CathPCI Registry of

117 nitions to be used in clinical trials of PVL closure devices.

118 PFO closure did not meet the primary endpoint of reduction i

119 , which result from a failure of neural tube closure during embryogenesis.

120 djustment for treatment allocation bias, LAA closure during routine cardiac surgery was significantly

121 We found that short-lived channel closures during channel openings represent subtle change

122 s - 'neural tube defects' - that result when closure fails.

123 Inspired by the stomatal closure feature of plant leaves at relatively high tempe

124 esults associated with left atrial appendage closure, focusing on procedural and late outcomes, and p

125 otein, leading to potent inhibition of wound closure following PMN-MP binding to IECs.

126 sociated with hydraulic failure and stomatal closure for 13 temperate and tropical forest biomes acro

127 , FOXC1, ATXN2, TXNRD2); PACG (primary angle-closure glaucoma (EPDR1, CHAT, GLIS3, FERMT2, DPM2-FAM10

128 open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) eyes.

129 primary angle closure (PAC) or primary angle-closure glaucoma (PACG) in both eyes.

130 atous VF loss in patients with primary angle-closure glaucoma (PACG) using pointwise linear regressio

131 rimary angle closure (PAC) and primary angle closure glaucoma (PACG), and to compare their diagnostic

132 h IOP higher than 35 mm Hg, and 1 with angle-closure glaucoma not attributed to the study drug or pro

133 nificant visual comorbidities, such as angle closure glaucoma, cystic macular edema, and exudative re

134 urred in 6 of 441 patients (1.4%) in the PFO closure group and in 12 of 223 patients (5.4%) in the an

135 ned cause occurred in 10 patients in the PFO closure group and in 23 patients in the medical-therapy

136 occurred in 23.1% of the patients in the PFO closure group and in 27.8% of the patients in the antipl

137 Subjects in the PFO closure group had a significantly greater reduction in h

138 farctions was significantly lower in the PFO closure group than in the antiplatelet-only group (22 pa

139 of atrial fibrillation was higher in the PFO closure group than in the antiplatelet-only group (4.6%

140 s was unequal (3141 patient-years in the PFO closure group vs. 2669 patient-years in the medical-ther

141 o PFO closure plus antiplatelet therapy (PFO closure group) or to receive antiplatelet therapy alone

142 ic stroke to undergo closure of the PFO (PFO closure group) or to receive medical therapy alone (aspi

143 nts occurred in 6 patients (1.4%) in the PFO closure group, and atrial fibrillation occurred in 29 pa

144 e occurred among the 238 patients in the PFO closure group, whereas stroke occurred in 14 of the 235

145 ys instability resulting in premature airway closure has been recognized as a risk for asthma severit

146 Neural tube closure has been studied for many decades, across a rang

147 abscisic acid (ABA) in VPD-induced stomatal closure has been studied using ABA-related mutants that

148 t decade, percutaneous left atrial appendage closure has emerged as a valid alternative to anticoagul

149 The blinking rate, eye closure, heart rate, alpha and beta band power were used

150 direct cost (including readmission/ileostomy closure hospitalizations) were significantly greater in

151 that could be engineered to impact stomatal closure in a controlled fashion and also provide over 14

152 osterol, were confirmed to regulate stomatal closure in Arabidopsis thaliana, B. napus or both specie

153 the fragment-5 region disrupted normal wound closure in both wild-type Hsp90alpha and Hsp90alpha-Delt

154 This is the first observation of a PVS closure in connection with an abnormal cortical event th

155 Sulfate application caused stomatal closure in excised leaves and peeled epidermis.

156 on of a neutrophil chemokine and slows wound closure in HBE cells.

157 However, the clinical impact of LAA closure in humans remains inconclusive.

158 hinders its expansion and leads to premature closure in most instances.

159 dressing versus a control dressing on wound closure in patients with neuroischaemic diabetic foot ul

160 Failure of spinal closure in pre-spina bifida Zic2(Ku) mutant embryos is a

161 On the other hand, active stomatal closure in response to ABA and CO2 was found in several

162 ERA1 function was not required for stomatal closure in response to ABA and environmental factors.

163 Knockout mutants showed impaired stomatal closure in response to the drought stress hormone ABA an

164 sfected with PTP1B siRNA showed faster wound closure in response to VEGF.

165 that Nrl is required for selective chromatin closure in rods.

166 Although rescue of epidermal wound closure in the absence of macrophages promotes blastema

167 t the reaction proceeds via conrotatory ring closure in the triplet excited state.

168 ne treatments decreased ABA-induced stomatal closure in the wild type, but not Nr, with ethylene resp

169 t CD301b-depleted mice exhibit delayed wound closure in vivo, which could be rescued by topical IL-27

170 r runoff-associated inland and coastal beach closures) in stormwater biofilters (a common type of gre

171 The formation of nonlocal contact (loop closure) increases the time-dependent acceptor emission,

172 esult indicates that DELLA promotes stomatal closure independently of its effect on growth.

173 Laser ablation of this new closure initiation point causes neural fold separation,

174 ry closure (standard arm) or biological mesh closure (intervention arm).

175 r perineal hernia rate after biological mesh closure is a promising secondary finding that needs long

176 The process of neural tube closure is complex and involves cellular events such as

177 Therefore, rapid wound closure is crucial for proper tissue function and restor

178 anisation of actin filaments during stomatal closure is documented, the underlying mechanisms respons

179 the AMPAR desensitized state, where channel closure is facilitated by profound structural rearrangem

180 Thus, cytokinetic ring closure is promoted by moderate levels of both motor and

181 promoting cargo discharge and reducing pore closure ('kiss-and-run').

182 Left atrial appendage closure (LAAC) was approved by the U.S. Food and Drug Ad

183 ainly suffer from malfunction of the urethra closure mechanism.

184 HORMADs by disassembling these HORMA domain-closure motif complexes, but its mechanisms of substrate

185 tus, or intraperitoneal) repair with fascial closure (n = 104).

186 ted by folate compromises normal neural tube closure (NTC) and ciliogenesis.

187 After 20 weeks, wound closure occurred in 60 patients (48%) in the sucrose oct

188 l wound induced by laser ablation and during closure of a not fully confluent layer.

189 The efficacy of closure of a patent foramen ovale (PFO) in the preventio

190 Whether closure of a patent foramen ovale reduces the risk of re

191 s who had had a cryptogenic ischemic stroke, closure of a PFO was associated with a lower rate of rec

192 he left renal artery confirmed the effective closure of all vascular pathology.

193 y component needed for achieving carbon mass closure of alpha-pinene SOA.

194 ic sodium-glucose cotransporter SGLT1, or by closure of ATP-sensitive potassium channels after glucos

195 Closure of atrial septal defect with the AMPLATZER Septa

196 -related conjugation system in mediating the closure of autophagosomes and its implication in the stu

197 of superior outcomes and contributed to the closure of cancer surgery units.

198 after removal of cardiopulmonary bypass) and closure of chest.

199 The ring closure of domino protocol was highly stereoselective an

200 driven by favorable interactions formed upon closure of extracellular and intracellular "gates" and b

201 data monitoring committee (IDMC) recommended closure of FOCUS4-D because of a lack of activity.

202 itor of plant basal immunity, did not induce closure of hydathode pores in contrast to stomata.

203 y used in the dental clinic to obtain apical closure of immature permanent teeth with thin dentinal w

204 es above ca. 56 GPa, suggesting the imminent closure of its optical bandgap.

205 ceptor (mAChR) activation and the subsequent closure of KCNQ potassium channels.

206 asing effective pressure due to compactional closure of micro-fractures.

207 viour is consistent with observations of the closure of microcracks formed parallel to the covalent-s

208 One response is the closure of plasmodesmata, which reduces symplastic conne

209 e AMPLATZER Septal Occluder for percutaneous closure of secundum atrial septal defects.

210 calcium release by conformationally inducing closure of SR channels.

211 Pressure-induced closure of the 1.6 eV bandgap in (MA)PbI3 demonstrates t

212 al membrane protrusions and, ultimately, the closure of the aperture.

213 Closure of the band gap to form an all-organic molecular

214 Closure of the causeway culverts occurred concurrently w

215 a single-cell wound are investigated during closure of the defect.

216 ibutes to SHF-derived regions and the dorsal closure of the HT.

217 the intervention arm, followed by a layered closure of the ischioanal and subcutaneous fat and skin

218 time-dependent acceptor emission, while the closure of the labeled helix turn reduces this emission.

219 Our data suggest hydrolysis-independent closure of the NBD dimer, which is further stabilized as

220 orphology of the optic cup and stalk and the closure of the optic fissure were substantially rescued

221 studies have suggested that biological mesh closure of the pelvic floor improves perineal wound heal

222 had a cryptogenic ischemic stroke to undergo closure of the PFO (PFO closure group) or to receive med

223 ne aura, induces a rapid and nearly complete closure of the PVS around surface as well as penetrating

224 that deletion or depletion of GpsB prevents closure of the septal ring that in itself is PBP2x-depen

225 an, (2) the breakup of Gondwana, and (3) the closure of the Tethys Seaway.

226 These action potentials (APs) cause rapid closure of the trap and activate secretory functions of

227 Our results indicate that closure of the tunnel is driven by mechanical stresses t

228 adjusting hyo-laryngeal movements to achieve closure of the upper airway.

229 Closure of the vesicle interrupts free exchange with the

230 6,6-dioxides it has been found that the ring closure of the zwitterion leading to the formation of su

231 To temporally delineate closure of this critical period for leptin-stimulated gr

232 a leading cause of patient morbidity because closure often requires multimodality treatments over a p

233 he trial's activation on August 9, 2011, and closure on August 1, 2013.

234 s xylem loading depends on SKOR and stomatal closure on GORK in Arabidopsis, whereas both functions a

235 on the impact of successful percutaneous PVL closure on midterm outcomes.

236 To determine the effect of biological mesh closure on perineal wound healing after extralevator abd

237 oto-switchable following the reversible ring closure/opening of the central dithienylethene via irrad

238 me of any operative resection, such as stoma closure or revision.

239 trast, TAF had no inhibitory effect on wound closure or tight junction formation following injury.

240 To follow airway-epithelial wound closure over time, we lesioned small areas of the mouse

241 (OCT) angiography in eyes with primary angle closure (PAC) and primary angle closure glaucoma (PACG),

242 osure suspects (PACSs) or with primary angle closure (PAC) or primary angle-closure glaucoma (PACG) i

243 ned patients, in a 2:1 ratio, to undergo PFO closure plus antiplatelet therapy (PFO closure group) or

244 The comparison of PFO closure plus antiplatelet therapy with antiplatelet ther

245 The results showed that complete stomatal closure preceded the appearance of embolism in the leave

246 While some argue that complete stomatal closure precedes the occurrence of embolism, others beli

247 Failure of this closure process leads to open spina bifida, a common cau

248 unravel a new role of Foxg1 in promoting OF closure providing additional knowledge about the molecul

249 Although many reports suggest that wound closure rates depend on isolated cell speed and/or leade

250 ons, and that contact reductions from school closures, rather than age-specific mixing and travel, pr

251 t merocyanine isomers, as well as their ring-closure reaction back to the spiropyran form.

252 lkyne units as well as the transannular ring closure reaction of a nonconjugated diyne.

253 Intramolecular ring-closure reactions of the morpholine moiety with the flan

254 one UPLC, joint timing triggered by contact closure relays, and a script to retrieve the data.

255 nuclear antigen (PCNA) clamp binding/opening/closure/release, ptDNA binding/release, and ATP hydrolys

256 Our results show that proper optic fissure closure relies on Wnt8b suppression by Foxg1 in the nasa

257 Wound closure requires the activation of keratinocyte migratio

258 o path is faster than the direct 6-endo-trig closure, revealing the general exo-preference for the cy

259 bstituent at nitrogen failed to undergo ring-closure, several N-protecting groups were evaluated.

260 If the closure speed is high enough, the intensity of the swirl

261 Patients were randomly assigned to primary closure (standard arm) or biological mesh closure (inter

262 This includes six C-C ring-closure steps that, through intramolecular Friedel-Craft

263 patients undergoing percutaneous mitral PVL closure, successful percutaneous reduction of the PVL to

264 per orientation of the substrate prior to T1 closure such that the U5-A6 cleavage site becomes embrac

265 s of age or older diagnosed as primary angle-closure suspects (PACSs) or with primary angle closure (

266 ly to move in directions of increased canopy closure, tall trees, and uniform height, as well as avoi

267 Guard cells of are show greater ABA-induced closure than the wild type, reduced light-dependent guar

268 successive cellular migration events in VBW closure that explain early morphological changes underly

269 nt (taucf ), which describes the short-lived closures that interrupt open bursts, was greatly increas

270 coronal sutures, which contribute to suture closure through endochondral ossification, in a process

271 y PBP2b and positively regulates septal ring closure through its interactions with StkP-PBP2x.

272 bo facilitated and significantly accelerated closure time and increased tensile strength in mice, and

273 Trials of patent foramen ovale (PFO) closure to prevent recurrent stroke have been inconclusi

274 Water limitation of plants causes stomatal closure to prevent water loss by transpiration.

275 g a particular direction of conrotatory ring closure (torquoselectivity).

276 Flap closure traps the Gag cleavage sites within the catalyti

277 bridge formed in 47.2% (type II) and apical closure (type III) in 38.9% cases.

278 using a femtosecond laser and followed wound closure up to 6 hours by autofluorescence multiphoton mi

279 of succinate-pretreated hMSC enhanced wound closure, vascularization and re-epithelialization and co

280 tomy, patient factors, and management goals (closure versus sepsis control).

281 ical signal of drought that induces stomatal closure via QUAC1/ALMT12 and/or guard cell ABA synthesis

282 ly POAF among the patients who underwent LAA closure was 68.6% versus 31.9% for those who did not und

283 PFO closure was associated with an increased risk of atrial

284 to antiplatelet therapy alone; however, PFO closure was associated with higher rates of device compl

285 Wound closure was clinically evaluated.

286 ge-dependent expression pattern during wound closure was identified, including miR-31 and miR-200c.

287 LAA closure was independently associated with an increased r

288 ually impaired barrier function, while wound closure was more sensitive to TFV.

289 Delayed wound closure was, in part, attributable to damage of the base

290 anisms by which TRPM6 influences neural tube closure, we functionally characterized the role of TRPM6

291 ing and/or proposed to be involved in domain closure were produced and the corresponding PELDOR exper

292 ontraindications to anticoagulants or to PFO closure were randomly assigned to the alternative noncon

293 e) occurred 98 of 99 patients; 1 subject had closure with a covered stent.

294 Device success (access and closure with a nitinol cardiac occluder without death or

295 Lewis acid catalyzed ring closure with a thiophene dialcohol in 2% ethanol-dichlor

296 analyzed to estimate the association of LAA closure with early postoperative atrial fibrillation (PO

297 heterization) versus medical therapy and PFO closure with the Amplatzer PFO Occluder device (St.

298 Between 2008 and 2012, atrial septal defect closure with the AMPLATZER Septal Occluder was attempted

299 ns and requires a second surgical procedure (closure) with its own complications.

300 cal role in mammalian eyelid development and closure, with subsequent impact on ocular integrity.