ライフサイエンスコーパス: clue

1 sources may include aetiologically important clues.

2 Highly structured environments might offer clues.

3 eoretically predicted with some experimental clues.

4 on and coexpression) can be mined to provide clues.

5 interact, are starting to provide important clues.

6 isodic sex triggered by external or internal clues.

7 ildren with NF1 and may be useful diagnostic clues.

8 ts, such as body size, and migration provide clues.

9 f deafness has recently provided tantalizing clues.

10 ken symmetry state generally provides little clue about the possibility of other nearby ground states

11 ar to the ancient Pacific samples, providing clues about a potential homeland for the Polynesian chic

12 ontrol these responses may provide important clues about AMD pathogenesis and inform future therapies

13 This limitation provides new clues about designing materials with slow creep and the

14 sensory pathways under study and provide new clues about different circuits that may be involved in v

15 IGVL gene usage appears to provide clues about disease pathophysiology and tissue tropism.

16 schizophrenia and breast cancer, and provide clues about etiology.

17 itope, recognized by an antibody can provide clues about functional vulnerabilities and resistance me

18 evelopment and function and reveal important clues about how isoprenoid and sterol metabolism is inte

19 These modeling results provide clues about how neural properties important for cognitio

20 nase and an 'inactive' pseudokinase provides clues about how these enzymes were regulated in the past

21 tely in these studies, they provide valuable clues about how to successfully combine approaches for f

22 ture of the Campylobacter hook provides some clues about its divergence.

23 Such studies might also yield clues about pathways, which could be modulated by non-in

24 Their nuclei and comae composition reveal clues about physical and chemical conditions during the

25 rvations of the disease course provide fresh clues about prevention and treatment approaches.

26 for functional genomics, providing important clues about the cellular and biochemical mechanisms that

27 other congenital infections provide valuable clues about the complexities of management and the optim

28 The study also provides clues about the culture that created it, since tanning p

29 They yield key clues about the evolutionary assembly of the group's com

30 le-stranded DNA fragments, which may provide clues about the genesis of autoimmune diseases such as s

31 tuberculosis exposure settings provides new clues about the genetic control of human antimycobacteri

32 the dengue and yellow fever viruses provides clues about the influence of changes in climate on their

33 ker movements of rats and mice are providing clues about the logic of active sensation and the underl

34 DYT25-associated dystonia, respectively, and clues about the mechanisms underlying dystonia pathogene

35 s produced by these decays provide important clues about the origin, formation and thermal evolution

36 biotic stress tolerance besides offering new clues about the possible roles of BjERD4 in plant growth

37 e, we examined mutations in human cancer for clues about the regulation of the hydrophobic spines by

38 ng these questions could provide fundamental clues about the sources of individual differences in the

39 Furthermore, this study provides valuable clues about the structural requirements for selective A-

40 nderstanding how enzymes have evolved offers clues about their structure-function relationships and m

41 These features provide clues about TRM cell specialization, such as their abili

42 on of unknown compounds to uncover important clues about underlying disease mechanisms.

43 and may serve as a helpful ocular diagnostic clue and an indicator of posterior pole involvement, a r

44 different diseases, describing the clinical clues and neurophysiological patterns that may help the

45 Similar strategies brought epidemiological clues and prevention goals for genetic diseases.

46 has gathered momentum fueled by tantalizing clues and visionary goals.

47 checklist, the 3-point checklist, chaos and clues, and CASH (color, architecture, symmetry, and homo

48 resent a knowledge-based CLUster Evaluation (CLUE) approach for identifying the most informative part

49 Good clues are emerging that give mechanistic substance to th

50 arget of TNF-alpha-TTP regulation provides a clue as to how its functional activity may be used in a

51 sponse in macrophages, providing a potential clue as to why this bacterium is normally tolerated by t

52 Studying Archaea may provide clues as these organisms share characteristics with Euka

53 ng this critical period and thus may provide clues as to etiological mechanisms of this disorder.

54 m's performance on various surfaces can give clues as to gecko behaviour, as well as towards designin

55 nogenetic nematode Diploscapter pachys gives clues as to how 'ancient asexual' animals can exist.

56 n mature adult beta cell identity, revealing clues as to how adult beta cells can partially dediffere

57 Together these discoveries provide new clues as to how growth--dependent signals control cell g

58 genes conserved for AM symbiosis, providing clues as to how plant cells fine-tune their biology to e

59 ithin these intracellular domains, providing clues as to how posttranslational modifications and rece

60 NE-1 endogenous retroelements, providing new clues as to the development of Aicardi-Goutieres syndrom

61 Clues as to the future do help give us a possible scenar

62 cytes exposed to aggregated TTR, and provide clues as to the molecular and physiological basis of hea

63 l types, but co-expression clusters provided clues as to their function.

64 Our results also provide clues as to which disulfide bonds are formed between adj

65 ed conditions for observing hormesis provide clues as to why this mechanism has not been previously i

66 ms, and disease mutations provide functional clues, deletion from endogenous loci constitutes the gol

67 r of semaphorin family, serves as a guidance clue during embryonic development and is known as a cand

68 In the absence of such clues, exome sequencing is a useful technique for findin

69 While this feature might be interpreted as a clue for another significant (236)U input in the Baltic

70 fectors list in this article provides both a clue for researchers as to their function and a framewor

71 nts less present on the mutant are a crucial clue for spore germination.

72 on during chronic infection provides a vital clue for the design of novel therapeutic strategies targ

73 of axon regeneration, providing a molecular clue for the synaptic stabilization hypothesis of CNS re

74 cryptic splice sites providing an important clue for variant prioritization.

75 Results presented provide important clues for a better understanding on how this complex dis

76 Clues for a specific involvement of the thalamic reticul

77 ned from these trials has provided important clues for better treatments.

78 n-depth understanding could provide valuable clues for catalysis system design.

79 and peptide-based drug leads, identified as clues for Complement-directed therapeutic development, a

80 These observations may give clues for creating melanin-based radioprotectors.

81 enetic basis of RP, but also provide helpful clues for designing future studies to further investigat

82 Although there are some clues for designing such materials, they remain mainly u

83 and to elucidate the clinical and laboratory clues for detection of NAbs in this prototype of frequen

84 s approaches are compared, aiming to provide clues for developing new and controllable synthetic rout

85 innings of its origins may provide important clues for development of novel therapeutic and preventiv

86 cal, and metabolic features that can provide clues for diagnosis.

87 This finding may provide clues for discovering new approaches for controlling str

88 rties of soft tissues may provide additional clues for disease diagnosis.

89 l focus on detection of clinical and imaging clues for earliest diagnosis, prompt local tumor treatme

90 Our findings provide structural clues for exploiting IN multimerization as a new, attrac

91 l diversity in enzyme superfamilies, provide clues for functional inference for superfamily members o

92 to cladistic assignments and holds important clues for further exploration of microbial lifestyles.

93 such issues in siRNA study will provide new clues for further improved design of more efficient and

94 e Lon substrates has thus provided important clues for further understanding of the F. tularensis str

95 Our findings provide important clues for future research into asthma aetiology.

96 nding mode and binding site provide valuable clues for inhibitor design.

97 These findings provide additional clues for new strategies for NMO treatment and a wealth

98 transcription, respectively, and may provide clues for novel antiviral reagents.

99 cle responses in this population may provide clues for novel OSA interventions.

100 hwann cells that provide signals and spatial clues for promoting regeneration, the clinical outcome a

101 cific regulation of gephyrin while providing clues for rapid evolutionary events and allelic migratio

102 how stem cell niches are modulated provides clues for regenerative medicine.

103 how they regenerate should provide important clues for regenerative medicine.

104 ber of the TNF superfamily but give us vital clues for the design of activity-enhanced TR3-based canc

105 These findings should provide important clues for the design of hydrogenase mutants with increas

106 erstand inhibition by mambalgins and provide clues for the development of new optimized blockers of A

107 cer research community by providing detailed clues for the functional importance of particular mutati

108 These in vitro experiments provide clues for the identification of biological processes res

109 the diploid Nod-independent clade, providing clues for the identification of the specific determinant

110 onmusicians rely on the processing of visual clues for the integration of audiovisual information, wh

111 of these proteins was invaluable to provide clues for the observed spectroscopic behavior that resul

112 al design of the material and gives valuable clues for the production of biomimetic counterparts base

113 tanding of CYP3A regulation and offers novel clues for the role of miRNAs in the metabolism and distr

114 ediated protection but possibly also provide clues for the susceptibility to infection in different r

115 hypertrophic cardiomyopathy and may provide clues for the timely recognition of disease progression

116 ree and the metal-bound molecules, providing clues for their roles in cellular metabolism.

117 ion receptor chemistry and provide important clues for understanding biological activities of synthet

118 den of heart disease, and provides important clues for understanding the determinants of the geograph

119 ed for various factors may provide important clues for understanding the etiology of certain breast c

120 ey locations can therefore provide important clues for understanding the ocean's role in Pleistocene

121 es in closely related plant species provides clues for unravelling biosynthetic pathways and regulato

122 All of these provide clues for why the asymmetrical hexameric ATPase gp16 of

123 al bone biology (eg, denosumab) coupled with clues from patients with rare bone diseases (eg, romosoz

124 Next, clues from somatic variants of 10E8, identified by next-

125 important link between extant biota and the clues from the geologic record.

126 Clues from the structure-activity relationships lining u

127 r with the disease name will provide outcome clues, guide treatment, and aid prevalence estimates.

128 While clues have existed that endosomal trafficking is associa

129 is confined to critical periods may provide clues how to better treat amblyopia.

130 ), not color, provide the primary diagnostic clue in dermoscopy.

131 ements exhibit flexibility, which may hold a clue in understanding NPC assembly and function.

132 rations containing diagnostic or therapeutic clues in cancer, prenatal diagnosis, infectious diseases

133 sights into its gene regulation will provide clues in designing anti-CMV strategies.

134 Clues in this regard have come from the study of humans

135 th high throughput and will provide valuable clues in understanding cell mechanics.

136 Cancer Genome Atlas have provided important clues into carcinogenesis and discerned potentially drug

137 nctions of one IFT protein, IFT27, and offer clues into how IFT cargo is selected and transported.

138 ain's convoluted patterns can provide useful clues into normal and pathological brain function.

139 Furthermore, it offers fundamental clues into the molecular basis of MMP regulation by N-TI

140 improve diagnostic yield, provide additional clues into the pathophysiology, and offer an application

141 that may contribute to JIA and give us some clues into what may trigger this disease.

142 Identification of these patterns provides clues linking them with forced or intrinsic tropical-ext

143 The clinical clues, management strategy, surgical characteristics, vi

144 One clue may lie in two openings between transmembrane helix

145 c influences can provide clinically relevant clues of CVD risk.

146 ter acute liver failure, providing promising clues of integration and full in vivo functionality of t

147 0 muM), and X-ray crystal structures provide clues of possible intermolecular H-bonding modes.

148 The results offered clues of the carbon acquisition strategy of the foliar F

149 ermit their use in studying microenvironment clues of tumour progression and angiogenesis.

150 carriers among cultivated organisms provides clues on both the taxonomy of their producers and the re

151 modify prion disease phenotypes may provide clues on how to alter prion formation and lead to treatm

152 of the CaM-F142L mutation may provide novel clues on how to suppress excessive RyR2 Ca(2+) release b

153 Recent brain imaging studies provide some clues on mechanisms underlying the most common cause of

154 evel and, at the same time, will offer vital clues on the behavior of simple compartmentalized system

155 se (SCAD) controls in order to provide novel clues on the degree of involvement of GPVI signaling in

156 67) show discrete localisations that provide clues on the function of the protein and markers for org

157 ely the apoD receptor and provide additional clues on the mechanisms involved in apoD-mediated functi

158 Phylogenomic analysis provides clues on the origin and evolution of PriX.

159 This result gives clues on the tanning phenomenon carried out by polypheno

160 e CMS can sometimes be reached by phenotypic clues pointing to the mutated gene.

161 Clues provided by electrochemistry to understand these e

162 and studies of mouse models have yielded new clues regarding ASD pathophysiology.

163 role in motor control should offer important clues regarding cerebellar contributions to cognition.

164 ded a constitutively active dimer, providing clues regarding how the activation loop communicates wit

165 their downstream targets provides important clues regarding how these signaling cascades contribute

166 i with respect to the plasma membrane to get clues regarding its possible function.

167 recent developments have provided important clues regarding the gating mechanism for this family of

168 ry of cutlassfish but also reveals potential clues regarding the historic productivity and regional o

169 y to E. coli endonuclease IV, which provides clues regarding the mechanism of action.

170 rrant behaviors in young AS mice may provide clues regarding the neural circuit defects that occur in

171 emotionally regulated material provide some clues regarding the neural pathways that may underlie th

172 number of insights that may reveal important clues regarding the origin and epidemiology of the disor

173 This work provides the first clues regarding the regulation of survivin DEx3 mRNA spl

174 S. aureus These data could provide important clues regarding the virulence of P. aeruginosa in albumi

175 aries, we discuss how our framework provides clues regarding this enigma.

176 structural subunit, CotA, reveals structural clues related to the niche in which they are expressed.

177 ficantly associated with P-OMS, are clinical clues suggesting an underlying tumor.

178 d factor with inflammation-provides a strong clue that these approaches may have an impact in this gr

179 es, and clinical features provide invaluable clues that help clinicians distinguish among the various

180 We review here clues that help in the differential diagnosis with infec

181 This proof-of-concept study provides clues that hepatic USPIO uptake in patients with NASH is

182 eaction could be initiated provided valuable clues that led to the proposal of a "unifying" chain pro

183 Previous studies offered clues that mHTT may disrupt nucleocytoplasmic transport

184 Biochemical assays revealed clues that the core structure of LF3 was essential for i

185 The assigned structures contain clues that the preference of the (D)P diastereomer to su

186 with perceived stress, this study provides a clue to bridging clinical risk factors for cCSC to under

187 ticipate in its pathogenesis is an important clue to decipher the pathomechanism and develop efficien

188 rity in GCK CpG4 methylation might provide a clue to elaborate the pathogenesis of T2D.

189 These findings provide us a clue to elucidate a unique DNA repair system in Archaea.

190 Thus, these findings would provide a clue to explore ULK1 and its target miRNAs as potential

191 ts with BHD and represent a novel diagnostic clue to its early detection and diagnosis.

192 e tissue hormones and adipokines, could be a clue to mechanisms that underlie the association with de

193 as the 2(nd) policeman and provided a great clue to solve the diagnostic dilemma.

194 blisters on hands and feet may be a clinical clue to the diagnosis of anti-p200 pemphigoid.

195 estigations, but it may provide an important clue to the etiology of ALS, if replicated by other stud

196 These motor patterns provide a clue to the form of the underlying circuits [2-4] (but s

197 rential expression on proteins may provide a clue to the intricate atypical regulation of the VH4-34

198 length and at the catalytic site, provided a clue to the mechanism of P1 Doc action, as most proteins

199 Now we have a clue to the mechanism, as many of these images amplify 3

200 therefore are believed to hold an important clue to the pathogenesis.

201 human hepaciviruses, providing an intriguing clue to the zoonotic source of hepatitis C virus.

202 atologic features provide a major diagnostic clue to this disease grouping, as exemplified by the rec

203 in the wall deposition process appears as a clue to understand the capacity of the maximum latewood

204 during plant evolution could be an important clue to understanding diversification by the inheritance

205 e in studies of REase mechanism and may give clues to a code for designing RNAs that competitively in

206 B activation in microglia and offers further clues to a novel mechanism by which Hsp72 may protect ce

207 nvironment [7-9], pigmentation patterns give clues to an animal's habitat.

208 Some clues to Avpr1b function can be gained from its profile

209 lthough polygenic score analyses may provide clues to behavioral pathways that can serve as therapeut

210 of dental ontogenetic parameters can provide clues to better understand the adaptive nature of phenot

211 M-K-Ras4B HVR association provides plausible clues to CaM's regulatory action in PI3Kalpha activation

212 age interpretation and gives some diagnostic clues to confidently interpret computed tomographic or m

213 AAO) of Alzheimer's disease (AD) may provide clues to delay disease expression.

214 between bacteria and B. dorsalis and provide clues to develop potential biocontrol techniques against

215 mation gained from kinetic profiles provides clues to direct further mechanistic analysis by other ap

216 and their chromatin association may provide clues to disease mechanisms.

217 fy functional alleles that provide important clues to disease pathophysiology, but large-scale sequen

218 These provide clues to elucidate the binding site parameters and mecha

219 Our work provides important clues to elucidating the mechanism by which Fam13a may c

220 s-covered glaciers on Mars may likewise hold clues to environmental change.

221 These results may provide new clues to explain the anti-inflammatory effects of statin

222 Taken together, our findings may provide clues to further investigate the molecular mechanism und

223 We explain how ribosomopathies may provide clues to help explain Dameshek's paradox and highlight s

224 hus identification of this gene will provide clues to help understand regulation of Fe uptake in plan

225 cted by in silico algorithms and provide new clues to improving T-cell epitope identification.

226 ial morphology of Ar. ramidus for additional clues to its phylogenetic position with reference to Afr

227 ys involved in dedifferentiation may provide clues to its reversal.

228 This study provides important clues to magnetite formation in MTB through the discover

229 ization of viral proteins provides important clues to mechanisms by which viruses survive and spread.

230 Thus, they provide clues to paleoenvironments where such nesting sites occu

231 ing that they can provide not only important clues to pathogenesis but also may serve as potential no

232 t and morbidity of cardiac NL should provide clues to pathogenesis with translational implications fo

233 behaviors of signaling pathways can provide clues to pathway mechanisms.

234 in this T-cell mediate disease and provides clues to possible new therapies.

235 into the underlying mechanisms could provide clues to possible therapeutic opportunities in allergic

236 Carbonaceous meteorites contain clues to prebiotic chemistry because they preserve a rec

237 ly and receptor clustering; it also provides clues to pro- and anti-inflammatory signaling pathways b

238 Clinical clues to promote recognition of cardiac amyloidosis, car

239 tational modeling not only provides critical clues to recognize current knowledge of fibrosis develop

240 (PI3K)/Akt pathway integrates environmental clues to regulate cell growth and survival.

241 abundances of elements in stars are critical clues to stars' origins.

242 newly emerging mephedrone analogs, and give clues to structural requirements that govern drug select

243 flap conformation of the enzyme and provided clues to target the flap pocket.

244 C. parvum may provide clues to the ancestral state of apicomplexan transcripti

245 lar gene expression in BC(-/-) mice revealed clues to the causes of the progressive retinal degenerat

246 pus callosum (CC) are important radiological clues to the diagnosis of multiple sclerosis (MS), but m

247 of the NEET protein family, as well as offer clues to the diverged functions of the human mitoNEET an

248 secondary metabolite production may provide clues to the ecological functions of specific compounds,

249 ic architecture of TGCT, and provide further clues to the etiology of TGCT.

250 ants can deeply impair TE dynamics and gives clues to the extraordinary diversity of TE evolutionary

251 Asteroids provide fundamental clues to the formation and evolution of planetesimals.

252 f chemical structure, details of which offer clues to the formation history of minerals.

253 To provide clues to the function of the claustrum, we compare the s

254 Mutant phenotypes provide strong clues to the functions of the underlying genes and could

255 in precursors to Ewing's sarcoma and provide clues to the histogenesis of Ewing's sarcoma in bone.

256 tical, as these unappreciated roles may hold clues to the ineffectiveness of kinase inhibitors in pat

257 xperiments are carried out provide important clues to the location of the mechanosensors and the kind

258 he SOD1 aggregation process and presents new clues to the mechanism by which hydrogen bonding maintai

259 l is required, these data provide intriguing clues to the mechanisms of post-transplant proteinuria i

260 A new study reveals clues to the mode of killing.

261 eroxiredoxins and enolase, which may provide clues to the molecular mechanisms enabling males to repr

262 ogical localization of alpha-synuclein gives clues to the nonsynaptic mode of alpha-synuclein propaga

263 e most recent common ancestry, thus offering clues to the origins of our own thoroughgoing reliance o

264 ute exacerbation of CRS may provide valuable clues to the pathogenesis and perpetuation of the diseas

265 sease risk factors and may provide important clues to the pathogenesis of Nasu-Hakola disease and oth

266 These results may provide clues to the pathologic mechanisms underlying certain ps

267 RC DNA to CCC DNA, thus providing important clues to the pathways of CCC DNA formation.

268 rose 4-phosphate, a pathway that may provide clues to the preferential metabolism of erythritol by Br

269 s of these chaperones and regulators provide clues to the prevention of amyloid disease, as well as t

270 This finding offers clues to the previously unknown structure of the ion-pum

271 ic features of the mycobacteria RNAP provide clues to the profound instability of mycobacteria RPo co

272 ether with atmospheric modelling, then gives clues to the properties of the exoplanet's atmosphere.

273 Clues to the responsible mechanisms may lie with the dis

274 s of these enzymes at these stages and offer clues to the role of the Trx/Prdx system during embryoni

275 Clues to the supramolecular arrangement of the molecules

276 structural details-can provide unprecedented clues to the underlying mechanisms and help therapeutics

277 -)-N and total phosphorus, offering tangible clues to the underlying mechanisms of soil biogeochemica

278 Thus, the current study provides several clues to the understanding of the neural control of the

279 re available for southern and central Tibet, clues to the uplift history of northern Tibet remain spa

280 ing a unique apical morphology that provides clues to their ability to capture microbial particles.

281 Their biogeography provides essential clues to their cryptic relationship with hosts and the e

282 and gene networks are providing significant clues to their etiology.

283 in certain regions of the transcript, giving clues to their function.

284 primary particles measuring <100 nm provided clues to their origin.

285 olates of various known origin might provide clues to their origin.

286 Hence, evidence of asymmetry may provide clues to underlying population structure, even when dire

287 Our results provide clues to understanding transmission of specific fears ac

288 s with central corneal thickness may provide clues to understanding why a thinner cornea increases th

289 cular network that could provide significant clues to various psychiatric illnesses.

290 We sought to identify "clues" to predict the observed historic diversification

291 These findings provide new clues toward a better understanding of the molecular mec

292 xyloglucan biosynthetic machinery will give clues toward engineering plants with improved wall prope

293 ound in the helpless model which may provide clues toward understanding the human disease.

294 The difference is a vital clue towards understanding why these dense mantle minera

295 GRAS-BIRD interactions and provide valuable clues towards our understanding of these regulators, whi

296 We combine this set of clues using a Bayesian classifier that reports the likel

297 Using this clue, we synthesized PTK1, harboring a methyl substituti

298 tructure of the JA receptor and evolutionary clues, we succeeded in modifying the JA receptor to allo

299 ith positive oxidase test were two important clues which could help clinicians to make the diagnosis

300 There are several clues which may indicate an ethiopathogenesis role for H