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1 Using clustered regularly interspaced short palindromic repeat
2 The CRISPR (clustered regularly interspaced short palindromic repeat
3 ds-especially those that utilize the CRISPR (clustered regularly interspaced short palindromic repeat
4 Clustered regularly interspaced short palindromic repeat
5 Based on clustered regularly interspaced short palindromic repeat
6 rate that targeting MUC1-C with silencing by clustered regularly interspaced short palindromic repeat
7 r-like (TAL) effector nucleases (TALENs) and clustered regularly interspaced short palindromic repeat
8 fragments of foreign DNA are integrated into Clustered Regularly Interspaced Short Palindromic Repeat
9 Recently, the RNA-guided CRISPR (clustered regularly interspaced short palindromic repeat
10 We name the tool CRISPR-ERA, for clustered regularly interspaced short palindromic repeat
11 ine the role of XIRP2 in hearing, we applied clustered regularly interspaced short palindromic repeat
12 olve inducible defense using the CRISPR-Cas (clustered regularly interspaced short palindromic repeat
13 wn for its role in the bacterial and archeal clustered regularly interspaced short palindromic repeat
14 In addition, we compared RNAi technology to clustered regularly interspaced short palindromic repeat
15 vents did not affect virus antigenicity, and clustered regularly interspaced short palindromic repeat
16 The clustered regularly interspaced short palindromic repeat
17 DNA of specific 30-40-base-pair lengths into clustered regularly interspaced short palindromic repeat
18 Clustered regularly interspaced short palindromic repeat
19 oreign (viral or plasmid) DNA fragments into clustered regularly interspaced short palindromic repeat
20 Clustered regularly interspaced short palindromic repeat
21 rectly into the intestine, a Cryptosporidium clustered regularly interspaced short palindromic repeat
22 NA (shRNA) or functionally ablated using the clustered regularly interspaced short palindromic repeat
23 ll line generated by genome editing with the clustered regularly interspaced short palindromic repeat
24 Clustered regularly interspaced short palindromic repeat
25 osomally integrated synthetic constructs and clustered regularly interspaced short palindromic repeat
26 fector complex of the Cmr/type III-B CRISPR (clustered regularly interspaced short palindromic repeat
27 We used clustered regularly interspaced short palindromic repeat
28 The recently discovered clustered regularly interspaced short palindromic repeat
29 The prokaryotic immune system clustered regularly interspaced short palindromic repeat
30 ted as such harbored an insertion in the 3rd clustered regularly interspaced short palindromic repeat
31 guided DNA endonuclease from the CRISPR-Cas (clustered regularly interspaced short palindromic repeat
32 FGE), multilocus sequence typing (MLST), and clustered regularly interspaced short palindromic repeat
33 scription activator-like effector nucleases, clustered regularly interspaced short palindromic repeat
34 The clustered regularly interspaced short palindromic repeat
35 The CRISPR (clustered regularly interspaced short palindromic repeat
36 or-like effectors (TALEs) and the RNA-guided clustered regularly interspaced short palindromic repeat
37 activator-like effector nuclease (TALEN) and clustered regularly interspaced short palindromic repeat
38 Clustered regularly interspaced short palindromic repeat
39 us in the host chromosome known as a CRISPR (clustered regularly interspaced short palindromic repeat
40 METHODS AND Here, we packaged SaCas9 (clustered regularly interspaced short palindromic repeat
41 This proof-of-principle work shows that clustered regularly interspaced short palindromic repeat
42 Bacterial and archaeal clustered regularly interspaced short palindromic repeat
43 The clustered regularly interspaced short palindromic repeat
44 es make use of small RNAs encoded by CRISPR (clustered regularly interspaced short palindromic repeat
45 Using the bacterial clustered regularly interspaced short palindromic repeat
46 Clustered regularly interspaced short palindromic repeat
47 otide polymorphisms (SNPs) and an indel in a clustered regularly interspaced short palindromic repeat
48 hia, Neisseria, Thermotoga, and Mycobacteria clustered regularly interspaced short palindromic repeat
49 Prokaryotic clustered regularly interspaced short palindromic repeat
50 nsecutive spacer-repeat units within a novel clustered regularly interspaced short palindromic repeat
51 nsporters for carbohydrates and peptides and clustered regularly interspaced short palindromic repeat
52 Two clustered regularly interspaced short palindromic repeat
53 Meanwhile, new technologies such as clustered regularly interspaced short palindromic repeat
54 In the present study, we used a clustered regularly interspaced short palindromic repeat
55 natal and adult-onset diabetes using CRISPR (clustered regularly interspaced short palindromic repeat
56 glycan (HSPG)-knockout (KO) cells by using a clustered regularly interspaced short palindromic repeat
57 of STING expression in endothelial cells by clustered regularly interspaced short palindromic repeat
58 Prokaryotic clustered regularly interspaced short palindromic repeat
59 Here, we develop clustered regularly interspaced short palindromic repeat
60 The clustered regularly interspaced short palindromic repeat
61 The prokaryotic clustered regularly interspaced short palindromic repeat
62 y small interfering RNA (siRNA) knockdown or clustered regularly interspaced short palindromic repeat
63 The clustered regularly interspaced short palindromic repeat
64 We used two CRISPR (clustered regularly interspaced short palindromic repeat
65 In many prokaryotes, type III clustered regularly interspaced short palindromic repeat
66 tagged Rab5c or Rab7a or lacking Cdc42 using clustered regularly interspaced short palindromic repeat
67 and A549 cells were genetically modified by clustered regularly interspaced short palindromic repeat
68 TPCN2 knockout by means of clustered regularly interspaced short palindromic repeat
69 Clustered regularly interspaced short palindromic repeat
70 ned by a combination of analysis of cellular clustered regularly interspaced short palindromic repeat
71 nal genomic technologies in combination with clustered regularly-interspaced short palindromic repeat
72 The CRISPR (clustered regularly interspaced short palindromic repeat
73 mprinted genes during seed development using Clustered Regularly Interspaced Short Palindromic Repeat
74 The clustered regularly interspaced short palindromic repeat
75 Clustered regularly interspaced short palindromic repeat
76 Delivery by adeno-associated virus (AAV) of clustered regularly interspaced short palindromic repeat
77 By taking advantage of the clustered regularly interspaced short palindromic repeat
78 ted protein 9), derived from type II CRISPR (clustered regularly interspaced short palindromic repeat
79 cterial adaptive immune systems use CRISPRs (clustered regularly interspaced short palindromic repeat
80 The clustered regularly interspaced short palindromic repeat
81 Unique among these are the CRISPR-Cas (clustered regularly interspaced short palindromic repeat
82 d that Argonautes encoded within CRISPR-cas [clustered regularly interspaced short palindromic repeat
83 rating fragments of foreign DNA into CRISPR (clustered regularly interspaced short palindromic repeat
84 present a high-throughput approach that uses clustered regularly interspaced short palindromic repeat
85 genic differentiation from a high-efficiency Clustered regularly interspaced short palindromic repeat
86 Clustered regularly interspaced short palindromic repeat
87 Using clustered regularly interspaced short palindromic repeat
88 terspaced short palindromic repeats (CRISPR)/clustered regularly interspaced short palindromic repeat
89 The Clustered Regularly Interspaced Short Palindromic Repeat
90 We used clustered regularly interspaced short palindromic repeat
91 We show that the type I-E CRISPR (clustered regularly interspaced short palindromic repeat
92 Clustered regularly interspaced short palindromic repeat
93 ing single-cell RNA sequencing (RNA-seq) and clustered regularly interspaced short palindromic repeat
94 ith the discovery of RNA-guided CRISPR-Cas9 (clustered regularly interspaced short palindromic repeat
95 idine deaminase (AID) with nuclease-inactive clustered regularly interspaced short palindromic repeat
96 ase allele-corrected intestinal tissue using clustered regularly interspaced short palindromic repeat
97 The barcode, an array of clustered regularly interspaced short palindromic repeat
98 endonuclease Cas9 from the microbial CRISPR (clustered regularly interspaced short palindromic repeat
99 nome-editing methods, especially the CRISPR (clustered regularly interspaced short palindromic repeat
100 The recently discovered clustered regularly interspaced short palindromic repeat
101 Clustered regularly interspaced short palindromic repeat
102 Nix knockout with clustered regularly interspaced short palindromic repeat
103 and harness these capabilities, we developed clustered regularly interspaced short palindromic repeat
104 tivator-like effector nucleases (TALENs) and clustered regularly interspaced short palindromic repeat
105 of prokaryotic adaptive immunity mediated by clustered regularly interspaced short palindromic repeat
106 sing patients' mutations were generated with clustered regularly interspaced short palindromic repeat
107 use temperate phages to deliver a functional clustered regularly interspaced short palindromic repeat
108 ided surveillance complexes that use CRISPR (clustered regularly interspaced short palindromic repeat
109 CRISPR-Cas (clustered regularly interspaced short palindromic repeat
110 We used engineered CRISPR (clustered regularly interspaced short palindromic repeat
111 Bacteria and archaea rely on CRISPR (clustered regularly interspaced short palindromic repeat
112 We developed a highly effective autonomous Clustered Regularly Interspaced Short Palindromic Repeat
113 s knocked out from the recipient cells using clustered regularly interspaced short palindromic repeat
114 We used clustered regularly interspaced short palindromic repeat
115 The prokaryotic immune system CRISPR-Cas (clustered regularly interspaced short palindromic repeat
116 Use of clustered regularly interspaced short palindromic repeat
117 The presence of clustered regularly interspaced short palindromic repeat
118 Clustered regularly interspaced short palindromic repeat
119 tandem-repeat (VNTR) analysis (MLVA), (iii) clustered regularly interspaced short palindromic repeat
120 CRISPR (clustered regularly interspaced short palindromic repeat
121 Genome editing via clustered regularly interspaced short palindromic repeat
122 Analysis of clustered regularly interspaced short palindromic repeat
123 We used clustered regularly interspaced short palindromic repeat
124 Bacterial adaptive immunity uses CRISPR (clustered regularly interspaced short palindromic repeat
125 archaea adaptive immune system consisting of clustered regularly interspaced short palindromic repeat
126 as9, an RNA-guided DNA endonuclease found in clustered regularly interspaced short palindromic repeat
127 Recently, the CRISPR (clustered regularly interspaced short palindromic repeat
128 Using the bacterial clustered regularly interspaced short palindromic repeat
129 elongation factor 2 (eEF-2) gene] using the Clustered Regularly Interspaced Short Palindromic Repeat
130 bacterial adaptive immune system mediated by clustered regularly interspaced short palindromic repeat
131 and integration of invader DNA into CRISPR (Clustered Regularly Interspaced Short Palindromic Repeat
132 Tal-effector nucleases (TALEN) and clustered regularly interspaced short palindromic repeat
133 CRISPR/Cas9-mediated (where CRISPR indicates clustered regularly interspaced short palindromic repeat
134 ns as well as single-cell gene editing using clustered regularly interspaced short palindromic repeat
135 i), Argonaute-based interference, as well as clustered regularly interspaced short palindromic repeat
136 unique antiviral defense system composed of clustered regularly interspaced short palindromic repeat
137 Clustered regularly interspaced short palindromic repeat
138 uses in vitro constituted nuclease-deficient clustered regularly interspaced short palindromic repeat
139 The discovery that the machinery of the Clustered Regularly Interspaced Short Palindromic Repeat
140 RNA) is one of the two key components of the clustered regularly interspaced short palindromic repeat
141 The clustered regularly interspaced short palindromic repeat
142 ite-specific insertion of a trait gene using clustered regularly interspaced short palindromic repeat
143 Clustered regularly interspaced short palindromic repeat
144 In bacteria, the clustered regularly interspaced short palindromic repeat
145 ke effector nucleases (TALENs) or RNA-guided clustered regularly interspaced short palindromic repeat
146 RNA regulatory element activity (GenERA), a clustered regularly interspaced short palindromic repeat
147 The term 'clustered regularly interspaced short palindromic repeat
148 The simplicity of programming the CRISPR (clustered regularly interspaced short palindromic repeat
149 ucleases constitute a core family of CRISPR (Clustered Regularly Interspaced Short Palindromic Repeat
150 rom RNA interference to gene knockouts using Clustered Regularly Interspaced Short Palindromic Repeat
151 Clustered regularly interspaced short palindromic repeat
152 Clustered regularly interspaced short palindromic repeat
153 adaptive immune systems, called CRISPR-Cas (clustered regularly interspaced short palindromic repeat
154 The type II clustered regularly interspaced short palindromic repeat
155 The clustered regularly interspaced short palindromic repeat
156 Clustered regularly interspaced short palindromic repeat
157 nterference (Swarts et al, 2014), as well as clustered regularly interspaced short palindromic repeat
158 This activity is in contrast to that of the clustered regularly interspaced short palindromic repeat
159 ing technologies-including in particular the clustered regularly interspaced short palindromic repeat
160 was to assess whether genome editing using a clustered regularly interspaced short palindromic repeat
161 n activator-like effector protein (TALE) and clustered regularly interspaced short palindromic repeat
162 Clustered Regularly Interspaced Short Palindromic Repeat
163 Clustered regularly interspaced short palindromic repeat
164 ancer model generation using the CRISPR/Cas (clustered regularly interspaced short palindromic repeat
165 tudy, we have applied the recently developed clustered regularly interspaced short palindromic repeat
166 Clustered regularly interspaced short palindromic repeat
167 s including zinc finger nucleases (ZFNs) and clustered regularly interspaced short palindromic repeat
168 The clustered regularly interspaced short palindromic repeat
169 acteria and archaea, small RNAs derived from clustered regularly interspaced short palindromic repeat
170 The bacterial clustered regularly interspaced short palindromic repeat
171 RNA-guided Cas9 nucleases derived from clustered regularly interspaced short palindromic repeat
172 Clustered regularly interspaced short palindromic repeat
173 Recently the type II prokaryotic clustered regularly interspaced short palindromic repeat
174 Clustered Regularly Interspaced Short Palindromic Repeat
175 ave evolved adaptive immune defenses, termed clustered regularly interspaced short palindromic repeat
176 The type II prokaryotic CRISPR (clustered regularly interspaced short palindromic repeat
177 RNA-guided Cas9 nuclease from the microbial clustered regularly interspaced short palindromic repeat
178 possess an adaptive immune system encoded by clustered regularly interspaced short palindromic repeat
179 al adaptive immune system is the CRISPR/Cas (clustered regularly interspaced short palindromic repeat
180 e-stranded DNA nuclease that participates in clustered regularly interspaced short palindromic repeat
181 hypervariable nature of virulence genes and clustered regularly interspaced short palindromic repeat
182 Clustered regularly interspaced short palindromic repeat
183 or-like (TAL) effector nuclease (TALEN)- and clustered regularly interspaced short palindromic repeat
184 ficiently and accurately using an engineered clustered regularly interspaced short palindromic repeat
185 ng capacity is 75% devoted to three distinct clustered regularly interspaced short palindromic repeat
186 CRISPRs (clustered regularly interspaced short palindromic repeat
187 y-generating retroelements and virus-encoded Clustered Regularly Interspaced Short Palindromic Repeat
188 t-deficient LEW.1WR1 rats using CRISPR-Cas9 (clustered regularly interspaced short palindromic repeat
189 DGCC7710 with phage 2972 and tracked CRISPR (clustered regularly interspaced short palindromic repeat
190 gical studies and disease treatment, and the clustered regularly interspaced short palindromic repeat
191 The main focus of this review is on CRISPR (clustered regularly interspaced short palindromic repeat
192 Clustered regularly interspaced short palindromic repeat
193 The CRISPR (clustered regularly interspaced short palindromic repeat
194 Clustered regularly interspaced short palindromic repeat
195 ing an adaptive immune response based on the clustered regularly interspaced short palindromic repeat
196 ated by a cassette-like genomic locus termed Clustered Regularly Interspaced Short Palindromic Repeat
197 CRISPR/Cas (Clustered Regularly Interspaced Short Palindromic Repeat
198 Clustered regularly interspaced short palindromic repeat
199 gments of virus-derived DNA into loci called clustered regularly interspaced short palindromic repeat
200 RNA transcribed from clustered regularly interspaced short palindromic repeat
201 egrating short fragments of foreign DNA into clustered regularly interspaced short palindromic repeat
202 In each case, transcripts derived from clustered regularly interspaced short palindromic repeat
203 Clustered regularly interspaced short palindromic repeat
204 Matches between S. enterica clustered regularly interspaced short palindromic repeat
205 egion of its genome that is distinguished by clustered regularly interspaced short palindromic repeat
206 The prokaryotic clustered regularly interspaced short palindromic repeat
207 Clustered regularly interspaced short palindromic repeat
208 ents of invader-derived DNA into loci called clustered regularly interspaced short palindromic repeat
209 Many bacteria and archaea contain clustered regularly interspaced short palindromic repeat
210 ve prokaryotic immune system arises from the clustered regularly interspaced short palindromic repeat
211 of FoxM1 to the cyclin B1 gene promoter via clustered regularly interspaced short palindromic repeat
212 dels with similar variants using the CRISPR (clustered regularly interspaced short palindromic repeat
213 We generated a human cell model of CHS using Clustered Regularly Interspaced Short Palindromic Repeat
214 Many bacterial clustered regularly interspaced short palindromic repeat
215 The RNA-guided, RNA-targeting clustered regularly interspaced short palindromic repeat
216 tem of adeno-associated virus (AAV)-mediated clustered regularly interspaced short palindromic repeat
217 tor-like effector nucleases (TALENs) and the clustered regularly interspaced short palindromic repeat
218 enome-wide small interfering RNA (siRNA) and clustered regularly interspaced short palindromic repeat
219 Using a CRISPR (clustered regularly interspaced short palindromic repeat
220 bining transposon-based transgenesis and the clustered regularly interspaced short palindromic repeat
221 From a genome-wide clustered regularly interspaced short palindromic repeat
222 Clustered regularly interspaced short palindromic repeat
223 Here we use clustered regularly interspaced short palindromic repeat
224 CRISPR (clustered regularly interspaced short palindromic repeat
225 of genome editing based on the CRISPR-Cas9 (clustered regularly interspaced short palindromic repeat
226 CRISPR-Cas (Clustered regularly interspaced short palindromic repeat
227 ciples of genome editing, recent advances in clustered regularly interspaced short palindromic repeat
228 ly interspaced short palindromic repeats and clustered regularly interspaced short palindromic repeat
229 The CRISPR (clustered regularly interspaced short palindromic repeat
230 Targeted gene disruption induced by Clustered Regularly Interspaced Short Palindromic Repeat
231 ls in which the PKD1 gene was knocked out by clustered regularly interspaced short palindromic repeat
232 Transcriptome analyses revealed that the clustered regularly interspaced short palindromic repeat
233 assessed the therapeutic efficacy of CRISPR (clustered regularly interspaced short palindromic repeat
234 Clustered regularly interspaced short palindromic repeat
235 Using a clustered regularly interspaced short palindromic repeat
236 The high efficiency of clustered regularly interspaced short palindromic repeat
237 Clustered regularly interspaced short palindromic repeat
238 tations associated with S-HSCR, and used the clustered regularly interspaced short palindromic repeat
239 e bacterial immune system, which is based on clustered regularly interspaced short palindromic repeat
240 However, the nuclear dynamics of clustered regularly interspaced short palindromic repeat
241 and genome engineering involving the CRISPR (clustered regularly interspaced short palindromic repeat
242 Applying clustered regularly interspaced short palindromic repeat
243 Clustered regularly interspaced short palindromic repeat
244 bacterial host also has two complete CRISPR (clustered regularly interspaced short palindromic repeat
245 Clustered regularly interspaced short palindromic repeat
246 activator-like effector nuclease and CRISPR (clustered regularly interspaced short palindromic repeat
247 nt tRNA-based vectors for producing multiple clustered regularly interspaced short palindromic repeat
248 ent method for gene disruption using CRISPR (clustered regularly interspaced short palindromic repeat
249 uence using integrative cotransformation and clustered regularly interspaced short palindromic repeat
250 kdown techniques, and the recently developed clustered regularly interspaced short palindromic repeat
251 eno-associated virus was used to deliver the clustered regularly interspaced short palindromic repeat
252 iption activator-like effector nucleases and clustered regularly interspaced short palindromic repeat
253 nd by TLR4 ablation in macrophages using the clustered regularly interspaced short palindromic repeat
254 iption activator-like effector nucleases, or clustered regularly interspaced short palindromic repeat
255 tivator-like effector nucleases (TALENs) and clustered regularly interspaced short palindromic repeat
256 We report here the use of the CRISPR (clustered regularly interspaced short palindromic repeat
257 We used clustered regularly interspaced short palindromic repeat
258 ngle-cell labeling of endogenous proteins by clustered regularly interspaced short palindromic repeat
259 itope tagging of the genomic MARCH6 locus by clustered regularly interspaced short palindromic repeat
260 We used CRISPR/Cas9 (clustered regularly interspaced short palindromic repeat
261 ning genome-wide epigenetic information with clustered regularly-interspaced short palindromic repeat
262 th enhancer activity, Enhancer L Strikingly, clustered regularly-interspaced short palindromic repeat
263 Among these, only clustered, regularly interspaced short palindromic repea
264 of most bacteria and archaea is an array of clustered, regularly interspaced short palindromic repea
265 een expanded to include the CRISPR system of clustered, regularly interspaced short palindromic repea
266 ion activator-like effectors (TALEs) and the clustered, regularly interspaced, short palindromic repe
267 loy surveillance complexes guided by CRISPR (clustered, regularly interspaced, short palindromic repe
268 Evidence from flies mutated using the clustered, regularly interspaced, short palindromic repe
269 Epigenome editing with the CRISPR (clustered, regularly interspaced, short palindromic repe
270 Genome editing with the clustered, regularly interspaced, short palindromic repe
271 The clustered, regularly interspaced, short palindromic repe
272 Clustered, regularly interspaced, short palindromic repe
273 Components of the prokaryotic clustered, regularly interspaced, short palindromic repe
274 roughput of genome editing based on type II, clustered, regularly interspaced, short palindromic repe
275 Clustered, regularly interspaced, short palindromic repe
276 Clustered, regularly interspaced, short palindromic repe
277 Clustered, regularly interspaced, short palindromic repe
278 Clustered, regularly interspaced, short palindromic repe
279 been largely fueled by the emergence of the clustered, regularly interspaced, short palindromic repe
280 n activator-like effector nucleases, and the clustered, regularly interspaced, short palindromic repe
281 We report the use of clustered, regularly interspaced, short palindromic repe
282 Clustered, regularly interspaced, short palindromic repe
283 teria, foreign nucleic acids are silenced by clustered, regularly interspaced, short palindromic repe
284 Here we use the clustered, regularly interspaced, short palindromic repe
285 erference pathway from bacteria [the type II clustered, regularly interspaced, short palindromic repe
286 y Island 1 (SPI-1), ste fimbrial operon, and Clustered, Regularly Interspaced, Short Palindromic Repe
287 okaryotes utilize small RNA transcribed from clustered, regularly interspaced, short palindromic repe
288 Clustered, regularly interspaced, short palindromic repe
289 Clustered, regularly interspaced, short palindromic repe
290 In prokaryotes, clustered, regularly interspaced, short palindromic repe
291 We initially used dual-CRISPR (clustered, regularly interspaced, short palindromic repe
292 Clustered, regularly interspaced, short palindromic repe
293 Clustered, regularly interspaced, short palindromic repe
294 The clustered, regularly interspaced, short palindromic repe
295 of site-specific genome targeting by type II clustered, regularly interspaced, short palindromic repe
296 ctivator-like effector nucleases (TALENs) or clustered, regularly interspaced, short palindromic repe
297 Discovery of clustered, regularly interspaced, short palindromic repe
298 Clustered, regularly interspaced, short palindromic repe
299 The clustered, regularly interspaced, short palindromic repe
300 We developed a method that uses CRISPR (clustered, regularly interspaced, short palindromic repe
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