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1 ase originally identified as a transcription co-activator.
2 ependent of the mitochondrial effects of the co-activator.
3 orylation inactivates Cdc20, a mitotic APC/C co-activator.
4 Yes-associated protein (YAP) transcriptional co-activator.
5 6) associated with the MAML1 transcriptional co-activator.
6 mulation of the beta-catenin transcriptional co-activator.
7 of POP-1 and functions as a transcriptional co-activator.
8 and association of transcription factors or co-activators.
9 arget genes; Tudor-SN is likely one of these co-activators.
10 ctivity of mERbeta isoforms with EDCs and ER co-activators.
11 cal for interactions with both receptors and co-activators.
12 receptors but also for the association with co-activators.
13 hibition is coupled to degron recognition by co-activators.
14 muscle genes through the myocardin-family of co-activators.
15 d binding sites of transcription factors and co-activators.
17 ssociated factor (PCAF) and steroid receptor co-activator 1 (SRC-1), the full length ACTN4 protein ei
18 r peroxisome proliferator-activated receptor co-activator 1 alpha (PGC1alpha) and its splice variant
19 DNA sequence variation in PPAR gamma (PPARG) co-activator 1 alpha (PPARGC1A), a gene encoding a co-ac
20 a lipid-sensing transcription factor (PPARG co-activator 1 alpha, PPARGC1A) to age-related macular d
21 xisome proliferator-activated receptor gamma co-activator 1-alpha (PPARGC-1-alpha or PGC-1alpha), als
24 (LBD) interactions with the steroid receptor co-activator-1 (SRC-1) peptide, displacing SRC-1 binding
26 xisome proliferator-activated receptor gamma co-activator-1 alpha (PGC-1alpha) positively regulates t
28 xisome proliferator-activated receptor gamma co-activator-1 alpha, positively control human OPN promo
29 element modulatory factor/androgen receptor co-activator 160), the key mediator of STAT3 ubiquitinat
30 xisome proliferator-activated receptor gamma co-activator-1a (PGC-1alpha), phosphoenolpyruvate carbox
31 xisome proliferator-activated receptor gamma co-activator 1alpha (PGC-1alpha), has emerged as a major
32 xisome proliferator-activated receptor gamma co-activator 1alpha (Pgc1alpha), leading to increased ac
33 n indirectly by modulating SP1 and PPARgamma co-activator 1alpha expression and/or activity independe
34 own of proliferator-activated receptor gamma co-activator 1alpha inhibits spinogenesis and synaptogen
36 urons, proliferator-activated receptor gamma co-activator 1alpha overexpression increases dendritic s
37 xisome proliferator-activated receptor gamma co-activator 1alpha), a transcriptional co-activator tha
39 xisome proliferator-activated receptor gamma co-activator 1alpha, a master regulator of mitochondrial
40 xisome proliferator-activated receptor gamma co-activator-1alpha (PGC-1alpha) and PGC-1beta, both of
41 xisome proliferator-activated receptor gamma co-activator-1alpha (Pgc-1alpha) is critical for cardiac
42 t that proliferator-activated receptor gamma co-activator-1alpha and mitochondrial biogenesis have im
44 ulates proliferator-activated receptor gamma co-activator-1alpha-dependent mitochondrial biogenesis b
45 xisome proliferator-activated receptor-gamma co-activator-1beta) and the nuclear receptor ERRalpha (e
47 ificantly overexpressed and nuclear receptor co-activator 4 (NCOA4) suppressed in colons of C. diffic
49 the activation of Wnt ligands, receptors and co-activators accompanies the inactivation of Wnt antago
51 or of this pathway is YAP, a transcriptional co-activator amplified in mouse and human cancers where
52 rovide evidence that G9a functions both as a co-activator and a co-repressor to enhance cellular prol
53 Z) is a WW domain-containing transcriptional co-activator and a core component of an emerging Hippo s
54 r, RORgammat encoded by Rorc, by acting as a co-activator and co-repressor of STAT3, respectively.
56 nserved component of several transcriptional co-activator and histone acetyltransferase (HAT) complex
57 ently, TRIM24 functions as a transcriptional co-activator and recruits STAT3, leading to stabilized S
58 ical interactions with the Eyes absent (Eya) co-activator and the Groucho (Gro) co-repressor, but the
60 AD3 interacts with reprogramming factors and co-activators and co-occupies OCT4 target loci during re
61 levels and respective interactions with the co-activators and co-repressors during erythroid develop
63 HIF-1alpha transactivating domain to recruit co-activators and diminished target gene expression.
66 se enhancers are occupied by transcriptional co-activators and loop onto the hes1 promoter within the
67 ine-rich (SR) proteins, a family of splicing co-activators, and thereby regulate the splicing of G6PD
69 a process called sigma appropriation, the T4 co-activator AsiA structurally remodels the sigma(70) su
70 ge promoters using an activator (MotA) and a co-activator (AsiA), which function through interactions
72 a Tet-on CHO cell reporter system, RORalpha co-activator assays and inhibition of (RORE)-LUC reporte
76 ith other endogenous transcription factor as co-activator (ATF3-JunB) or co-repressor (ATF3-NFkappaB)
77 nt protein interfaces on the transcriptional co-activator beta-catenin provides part of the answer.
78 target genes by promoting association of the co-activator beta-catenin with TCF/LEF transcription fac
79 including some utilizing the transcriptional co-activator beta-catenin, has limited the ability of cl
80 tion between the Wnt pathway transcriptional co-activators beta-catenin/Armadillo and TCF to facilita
81 ed RORgammat-driven transcription, decreased co-activator binding and promoted interaction with co-re
82 tomistic disordered ensembles of the nuclear co-activator binding domain (NCBD) of transcription coac
83 n of the interaction kinetics of the nuclear co-activator binding domain of CREB-binding protein and
84 at the expression of PIMT, a transcriptional co-activator binding protein, was up-regulated in the so
85 y a complex network of factors that includes co-activator binding, autophosphorylation, and dephospho
86 (Nucleosome acetyltransferase of histone H4) co-activator, but not activator Rap1p (repressor-activat
87 It usually functions as a transcriptional co-activator by associating with H3K4me3 and RNA polymer
90 mRNAs, whereas concentrations of the T-cell co-activators CD80 and CD86 increased in parallel with r
91 by catalysing the incorporation of the APC/C co-activator, CDC20, into a complex called the mitotic c
93 ion rate of 15 known substrates of the APC/C co-activator Cdh1 under normal conditions and conditions
94 gene, and fzr-1, an orthologue to the APC/C co-activator Cdh1, completely eliminates the essential r
98 NA binding domain and a conserved N-terminal co-activator/co-repressor (COAR) domain consisting of A1
99 ntially induced in GSCs by a HIF1alpha/STAT3 co-activator complex and stabilizes Notch1 protein at th
102 TA1/polymerase II/activator protein-1 (AP-1) co-activator complex interacts with the FosB-gene chroma
104 a component of the MEDIATOR transcriptional co-activator complex led us to address its involvement i
107 iated factor complex (PAFc) is an epigenetic co-activator complex that makes direct contact with MLL
108 port that depletion of the components of the co-activator complex, Mediator, specifically and potentl
111 quired for the T3-induced recruitment of the co-activator CREB-binding protein (CBP) and release of n
115 ding protein (Creb1) and its transcriptional co-activators (Crtc1-3) as targets of miR-17, miR-144, a
118 romotes dephosphorylation of transcriptional co-activators CRTC2/3 resulting in enhanced gluconeogeni
119 sphorylation of CREB-regulated transcription co-activators (CRTCs) whose aberrant activation is linke
120 d protein (YAP) are critical transcriptional co-activators downstream of the Hippo pathway involved i
121 tial activator SIRT1, or its binding partner/co-activator EP300 inhibited RGZ induction of PPARgamma-
122 tivation of the enhancers and recruitment of co-activators, exemplified by p300, causing both enhance
123 ion of the transcription factor Six1 and its co-activator Eya1, develops into placodes and ultimately
124 er the methyltransferase and transcriptional co-activator EZH2 controls the differentiation clock of
125 icate that tissue-restricted transcriptional co-activators facilitate cell-specific Wnt/Wingless sign
126 e GRF-INTERACTING FACTOR (GIF) transcription co-activator family of Arabidopsis thaliana (Arabidopsis
127 Drosophila CREB-binding protein (dCBP) is a co-activator for Caudal-regulated activation of ftz.
129 findings suggest a novel role for BTG2 as a co-activator for NFE2L2 in up-regulating cellular antiox
131 ivation domain from the p160 transcriptional co-activator for thyroid hormone and retinoid receptors.
134 at the inhibition of the YAP transcriptional co-activator function by PTPN14 is mediated through thei
135 ses reveal that CARM1 exerts transcriptional co-activator function on autophagy-related and lysosomal
137 uitment of the elongation factor P-TEFb, the co-activator GRIP1, the chromatin remodeling factor BRG1
138 ococcus pneumoniae, the core enzyme GtfA and co-activator GtfB form an OGT complex to glycosylate the
139 iogenesis in yeast (i.e. the transcriptional co-activator Hap4p) is positively regulated by the cellu
146 The potential role of c-Jun and specific co-activators in the action of TGF-beta was investigated
147 rylation-dependent interaction of Elk-1 with co-activators, including histone acetyltransferases and
148 mechanisms driving differential beta-catenin/co-activator interactions and their role in adult somati
149 C) signaling regulates specific beta-catenin/co-activator interactions to promote adult progenitor ce
151 Creb3l3 mRNA, which encode a transcriptional co-activator involved in energy metabolism and a liver-s
152 owth factor (LEDGF/p75) is a transcriptional co-activator involved in targeting human immunodeficienc
153 function as non-DNA-binding transcriptional co-activators involved in regulating metabolic and devel
155 to regulate the epigenetic activity of an ER co-activator KDM3A, ACK1 modulates HOXA1 expression in t
156 We report that ACK1 phosphorylates the ER co-activator, KDM3A, a H3K9 demethylase, at an evolution
157 amily member) interacts with transcriptional co-activators like CREB-binding protein (CBP) and its pa
161 action between serum response factor and its co-activator myocardin was reduced by overexpression of
162 r serum-response factor (SRF) along with its co-activator, myocardin-related transcription factor-A (
163 ecreased expression of progesterone receptor co-activators (NCOA1, -2 and -3, and CREBBP) towards ter
164 of miR-146b, downregulation of the PPARgamma co-activator NCOA4, and PPARgamma, leading to upregulati
165 o bind DNA and that a putative transcription co-activator NDP52 relieves the auto-inhibition of MVI t
166 eptor-gamma coactivator 1alpha, PGC1 related co-activator, nuclear respiratory factor 1, transcriptio
168 work identifies the MLL complex as a crucial co-activator of AR and a potential therapeutic target in
171 at the overexpression of the transcriptional co-activator of beta-catenin, transcription factor 7-lik
174 ssociated protein (YAP) is a transcriptional co-activator of hippo signaling pathway, which plays an
177 pha (PGC-1alpha), a critical transcriptional co-activator of metabolic gene expression, functions to
178 udies clearly indicate that PHD3 serves as a co-activator of NF-kappaB signaling activity in NP cells
179 ne methyltransferase 6 (PRMT6) is a specific co-activator of normal and mutant AR and that the intera
180 mouse model, in which an essential cytosolic co-activator of Nox2 is lost, to characterize bone metab
182 d the binding between TAp63gamma and p300, a co-activator of TAp63gamma, and consequently counteracte
187 ivator 1 alpha (PPARGC1A), a gene encoding a co-activator of the LCPUFA-sensing PPARG-retinoid X rece
188 he RNA helicase p68 (DDX5) is an established co-activator of the p53 tumour suppressor that itself ha
191 sent study we identified Tudor-SN as a novel co-activator of the transcription factor peroxisome prol
193 r work has focused on targeting AR directly, co-activators of AR signaling, which may represent new t
195 wed that Kto and Skd are not transcriptional co-activators of Rel2 or other key factors of the IMD pa
199 that certain isoforms of AUF1 can serve as "co-activators" of TTP family protein binding to RNA.
200 anscription factor that acts in concert with co-activators or co-repressors to control the activity o
202 ongation, potentially through recruitment of co-activators or release of co-repressors with unique ro
203 e present at the Stra6 RARE; 2) RA increases co-activator p300 (KAT3B) binding and histone H3 Lys-27
205 sulted in recruitment of the transcriptional co-activator p300 to a Bcl11b-repressed promoter with su
209 a-catenin with either of the homologous Kat3 co-activators, p300 or CREB-binding protein, differentia
210 transcription and protein levels of the Cdk5 co-activator p35 through ERK1/2, resulting in an increas
212 esis was most likely mediated by the nuclear co-activators peroxisome proliferator-activated receptor
214 an OPN showed that ERRalpha and its obligate co-activator, peroxisome proliferator-activated receptor
215 sity, enhanced expression of transcriptional co-activator PGC-1alpha and increased mitochondrial fatt
216 evels of a gluconeogenic enzyme G6Pase and a co-activator PGC-1alpha were all markedly decreased.
217 nsferase-1, and the integral transcriptional co-activator Pgc-1alpha were significantly downregulated
219 isome proliferators-activated receptor-gamma co-activator (PGC)-1alpha, a critical master of ROS meta
221 n muscle are mediated by the transcriptional co-activator PPAR-gamma co-activator-1 alpha (PGC1-alpha
222 the mitochondrial biogenesis transcriptional co-activator PPARgamma coactivator 1alpha (PGC-1alpha).
223 on of the adipogenic regulator PPARG and its co-activator PPARGC1B, and reduced expression of LPL.
224 ranscriptional mechanism.The transcriptional co-activator Prdm16 regulates browning of white adipose
225 bly checkpoint proteins Mad2, Mad3 and APC/C co-activator protein Cdc20), we reveal the molecular bas
226 F2C-bound sites by the SAP domain-containing co-activator protein myocardin, and we show that paired
228 ates Lys63-linked ubiquitination of the AP-1 co-activator RACO-1, leading to RACO-1 protein stabiliza
232 omoter occupancy and p300, a transcriptional co-activator, recruitment resulting in a defect in targe
233 was recently described as a transcriptional co-activator regulated by miR-135b in vestibular hair ce
234 langiectasia locus (NPAT), a transcriptional co-activator required for expression of histone genes in
235 tion of the NTD to facilitate the binding of co-activators required for maximal transcriptional activ
238 ere we use mathematical modelling to infer a co-activator role for LIGHT-REGULATED WD1 (LWD1) in CCA1
239 one fold-containing subunits of TFIID and of co-activator SAGA are important for the assembly of thes
240 s1p is a common component of transcriptional co-activator, SAGA (Spt-Ada-Gcn5-Acetyltransferase), and
241 ow that cells stably depleted of LKB1 or its co-activator STRADalpha have increased phosphorylation o
242 ns are assembled, and how they interact with co-activators, substrates and regulatory proteins is lim
243 ranscriptional activators via recruitment of co-activators such as EP300, whereas KLF3 and related me
244 ) interacts efficiently with transcriptional co-activators such as p300/CBP-associated factor (PCAF)
245 sets of target genes through recruitment of co-activators such as the RNA polymerase II-interacting
246 ear receptor alpha (ERalpha), which requires co-activators, such as steroid receptor coactivator-1 (S
248 lation of beta-catenin and its transcription co-activator Tcf4 led to activation of Wnt/beta-catenin
249 The Eya1 gene encodes a transcriptional co-activator that acts with Six1 to control the developm
251 ssociated protein (YAP) is a transcriptional co-activator that has been associated with bladder cance
252 recruitment of Gcn5 (also known as Kat2a), a co-activator that has been implicated in transcription i
253 SAGA complex is a conserved, multifunctional co-activator that has broad roles in eukaryotic transcri
254 amma co-activator 1alpha), a transcriptional co-activator that has powerful effects on mitochondria;
255 n-like protein 2 (MKL2) is a transcriptional co-activator that in response to RhoA and cytoskeletal a
256 d also its homologue TAZ) is a transcription co-activator that mediates the biological functions of t
257 otein (Yap) has emerged as a transcriptional co-activator that modulates tissue homeostasis in respon
258 n-expressor of PR1 (NPR1) is a transcription co-activator that plays a central role in regulating the
260 describe its oncogenic role as a HIF-1alpha co-activator that regulates the HIF-1 transcriptional ne
261 inding protein (CBP) are key transcriptional co-activators that are essential for a multitude of cell
263 00/CBP, which are ubiquitous transcriptional co-activators that interact with a variety of sequence-s
265 By inhibiting YAP and TAZ transcription co-activators, the Hippo pathway regulates cell prolifer
267 eta-catenin from acting as a transcriptional co-activator to TCF, yet without affecting its stability
269 ription in part by controlling the access of co-activators to their transcription factor partners.
271 ntified the RNA helicase DHX15 as a novel AR co-activator using a yeast mutagenesis screen and reveal
273 hrough cAMP-response element-binding protein co-activators, we depleted these co-activators using ade
274 ls for MYC and EBNA2 (an EBV transcriptional co-activator) were significantly enriched in the promote
275 e expression indirectly inhibits the YAP/TAZ co-activators, which maintain the clonogenic potential o
277 of this pathway are YAP/TAZ, transcriptional co-activators whose dysfunction contributes to epithelia
280 associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ) are its target
281 associated protein (YAP) and transcriptional co-activator with PDZ-binding motif (TAZ), are required
282 Hippo pathway effectors TAZ (transcriptional co-activator with PDZ-binding motif) and YAP (Yes-associ
285 reduces the activity of the transcriptional co-activator YAP and the expression of the NOTCH ligand
290 e and inhibit the downstream transcriptional co-activators YAP and TAZ, which are implicated in vario
292 y, the Hippo pathway and its transcriptional co-activator Yes-associated protein (YAP) have been show
296 MST2 negatively regulate the transcriptional co-activators yes-associated protein 1 and WW domain con
298 the interaction between the transcriptional co-activator Yorkie (Yki) and the transcription factor S
299 nuclear localization of the transcriptional co-activator Yorkie and initiation of growth and prolife
300 or the Hippo pathway and its transcriptional co-activator Yorkie in controlling Drosophila glial prol
301 t suppressed by removing the transcriptional co-activator Yorkie, suggesting that these roles of Fat
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