ライフサイエンスコーパス: co-culture

1 own in SF had an impact on KYSE-410 cells in co-culture.

2 n of different mammalian cell types grown in co-culture.

3 s, but also from MCF-7R to other cells after co-culture.

4 ulated and CCL11 was down-regulated in SF in co-culture.

5 ived astrocytes induce motor neuron death in co-culture.

6 ease LTB4 and to protect epithelial cells in co-culture.

7 lated and Ccl11 was down-regulated in CAF in co-culture.

8 ulation that confers fitness in interspecies co-culture.

9 cancer cell viability, and cancer growth in co-culture.

10 cells, also inducing IFN-stimulated genes in co-culture.

11 othelium structure lost its integrity in the co-culture.

12 ifferentiation, in the absence of glial cell co-culture.

13 nes and normal human dermal fibroblasts were co-cultured.

14 sed TJP expression in the Mtb-stimulated BBB co-cultures.

15 kers in vitro in both liquid and OP9-DeltaL1 co-cultures.

16 ly corrected by adding exogenous IL-2 to the co-cultures.

17 antisense RNA (Has2os2) was up-regulated in co-cultures.

18 normal skin fibroblasts (SF) only in direct co-cultures.

19 ooth muscle actin expression was detected in co-cultures.

20 ibroblasts and T lymphocytes was examined in co-cultures.

21 and synaptogenesis defects from ASD neuronal co-cultures.

22 based microfluidic device for 2D and 3D cell co-cultures.

23 bility compared with neuron/E2 and neuron/E3 co-cultures.

24 atment response in tumor spheroid/immunocyte co-cultures.

25 ibuted in a similar manner to pericytes in a co-cultured 3D model on increasing trans-endothelial ele

26 We co-cultured a diverse collection of natural isolates of

27 ompensate for each other's deficiencies upon co-culturing, a situation which implied the absence of g

28 In LAM cell-fibroblast co-cultures, acidification paralleled cathepsin K activi

29 In co-culture activating cells had reduced sensitivity to s

30 S sorting to show that, in mixed neuron glia co-cultures, activity-dependent regulation of metabolic

31 This co-culture also led to decreased CK-14 secretion and mor

32 s (HDACi) abrogated their ability to protect co-cultured AML cells from SDF-1-induced apoptosis.

33 nts differed according to cell type, stromal co-culture and culture format.

34 nd adhere well on glass surfaces in neuronal co-culture and form a monolayer of connected cells, we d

35 Co-culture and neutralizing antibody experiments reveal

36 ion of complex environments such as cellular co-culture and patient samples.

37 microbiology laboratories (including amoeba co-culture and shell-vial culture) and through the use o

38 oscopy of media from astrocyte-spinal neuron co-cultures and astrocyte-only cultures.

39 Proof-of-principle experiments on neuronal co-cultures and brain tissues reveal cell-type-dependent

40 Utilizing a series of strategies, including co-cultures and cellular microarrays, we identified dist

41 DAR1's effect on LSC self-renewal in stromal co-cultures and restores let-7 biogenesis.

42 We conceived a system that circumvents co-culturing and begins with a self-supporting cell that

43 ture systems, including co-culture, indirect co-culture, and transactivation, to assess the effect of

44 ng drug screening, tumor dissemination, cell co-culture, and tumor invasion.

45 ion in the laboratory with defined microbial co-cultures are being used to decipher the metabolic and

46 Although no successful co-cultures are observed in a two-strain ecology without

47 Met-induced PD-L1 expression, we performed a co-culture assay using mouse splenocytes (expressing PD-

48 Three-dimensional organotypic co-culture assays revealed that WNT2-mediated fibroblast

49 e clone-specific growth was then analysed in co-culture assays with all possible heterologous pairwis

50 In dendritic cell co-culture assays, priming with S. aureus promotes robus

51 ron and astrocytic-mediated neurotoxicity in co-culture assays.

52 r non-targeted equivalents using an in vitro co-cultured BBB model consisting of primary porcine brai

53 oproteomic time-course analysis of a 100-day co-culture between the model marine picocyanobacterium S

54 In mixed lymphocyte co-cultures between normal human peripheral blood lympho

55 Co-cultured BMFs or BMF-conditioned medium (BMF-CM) indu

56 reast fibroblasts increased proliferation of co-cultured breast cancer cells.

57 Organotypic co-cultures bridge the gap between standard two-dimensio

58 r Azospira suillum PS grew on perchlorate in co-culture, but not individually.

59 ose uptake with SOD1(G93A) expression in all co-cultures, but while co-cultures with only SOD1(G93A)

60 in growth promotion of PSCs was confirmed in co-culture by using their specific-inhibitors and exogen

61 This process is reversible in co-cultures by the anaerobic Fe(III)-reducing bacterium

62 d contributions of multiple cells within the co-culture capture the interactions between hepatocytes

63 Foxp3+Tregs (without Teff proliferation), by co-culturing CD4+ T-cells with OX40 L+Jagged(JAG)-1+ bon

64 ylls (1.6%, p<0.01), and were higher for the co-culture cell model compared to Caco-2 cells (p<0.01).

65 vitro digestion, cellular uptake (Caco-2 vs. co-culture cell model: Caco-2:HT-29-MTX (90:10%) and col

66 We explicitly demonstrate this exchange by co-culturing cell lines with distinct mtDNA haplotypes.

67 ur, reduced the AAPH pro-oxidant capacity in co-culture cells.

68 When multiple cell lines were co-cultured, cellular movement altered observed mutation

69 Using in vitro co-culture challenge assays, we quantified Bd inhibition

70 With an innovative co-culturing chamber together with advanced mass spectro

71 ar uptake of rod-shaped nanoparticles in the co-culture compared to spheres regardless of the presenc

72 newly synthesized or highly produced in the co-culture compared with individual cultures.

73 ates, when tested against wild-type pfcrt in co-culture competition assays.

74 In HSC-NPC co-culture, ConA-induced expression of inflammatory cyto

75 nces under both in vitro aqueous and in situ co-culture conditions.

76 ion between KCs and inflammatory cells under co-culture conditions.

77 roducing Microcystis strains under mono- and co-culture conditions.

78 8, and monocyte chemoattractant protein-1 by co-cultured dendritic cells, macrophages, monocytes, and

79 Co-cultured diatoms also downregulated lipid biosynthesi

80 Metabolomics study of this co-culture discovered that sixty-two features were eithe

81 x,y,z,t) visualization of neutrophils in the co-culture environment.

82 however studies of primary cells in complex co-culture environments often requires fluorescent label

83 e, GW4869, significantly reduces survival in co-cultured epithelial cells, signifying an important ro

84 tes is selectively toxic to motor neurons in co-culture, even when mutant protein is expressed only i

85 hBMSC and peripheral blood mononuclear cell co-cultured exosomes for improving islet transplantation

86 and peripheral blood mononuclear cell (PBMC) co-cultured exosomes.

87 The co-culture experiment of HCC cells with endothelial cell

88 We performed a co-culture experiment with human metastatic melanoma cel

89 Using co-culture experiments and mouse transcriptome analyses

90 Co-culture experiments found that preadipocytes activate

91 Furthermore, co-culture experiments showed that bone marrow derived D

92 Co-culture experiments support the existence of a novel

93 e performed long-term phototroph-heterotroph co-culture experiments under nutrient-amended and natura

94 Co-culture experiments were used to examine the effect o

95 Interestingly, co-culture experiments with FTD astrocytes revealed incr

96 In co-culture experiments with primary human T cells, epith

97 In in vitro co-culture experiments, M. tuberculosis-infected macroph

98 In Transwell co-culture experiments, mutant donor cells conferred miR

99 Based on co-culture experiments, we observed that ASD-derived ast

100 ) neurons while glutamate was reduced in all co-cultures expressing SOD1(G93A).

101 In co-cultures, fibrocytes induced on lung fibroblasts a si

102 ScNs and CN neurons were co-cultured for 4-6 days in the absence or presence of a

103 In primary neuron-glia co-cultures from P0 mouse hippocampi, male neurons have

104 ral and confocal microscopy of P. gingivalis-co-cultured GECs or green-fluorescent-protein (GFP)-P. g

105 t iNSCs are tumouritropic, homing rapidly to co-cultured glioblastoma cells and migrating extensively

106 lowing subcutaneous implantation in rodents, co-cultured hiPSC-MSC/-macrophage on such scaffolds show

107 ) were used as a 3-dimensional substrate for co-culturing HLE and CSSC.

108 ced the expression of contractile markers in co-cultured human aortic smooth muscle cells (HASMCs).

109 ty to differentiate and induced apoptosis in co-cultured human glioblastoma cells.

110 he human heart ("cardiac spheroids", CSs) by co-culturing human primary or iPSC-derived cardiomyocyte

111 tocytes and endothelial cells are seeded and co-cultured in the ECM-based micro-honeycomb to prepare

112 nd 3D spheroids of cervical tumor cells were co-cultured in the networks.

113 HNSCC spheroids were co-cultured in vitro with peripheral blood mononuclear c

114 ifferent types of culture systems, including co-culture, indirect co-culture, and transactivation, to

115 The addition of co-culture influenced (p<0.01) proteolysis in the cheese

116 using a 70% Caco2/30% HT-29 human intestinal co-culture layer.

117 Co-culture led to upregulated c-Maf expression with no d

118 Co-cultures maintained postprandial glucose concentratio

119 The isolation and co-culture methods could provide a stable platform for c

120 Complex co-culture micro-environmental analogues were also gener

121 cterized a primary human macrophage-enteroid co-culture model for in-depth studies of epithelial and

122 This simple and easy-to-implement human co-culture model may represent a sustainable and physiol

123 ltaT cell-bacterial interactions, an ex vivo co-culture model of human peripheral blood mononuclear c

124 A triple co-culture model of intestinal cells was utilized to mor

125 tight junction protein (TJP) expression in a co-culture model of the BBB.

126 urther, the newly devised and imaged primary co-culture model recapitulates key molecular mechanisms

127 es their ability to induce synaptogenesis, a co-culture model system incorporating GABAergic medium s

128 We present an advanced co-culture model to explore neutrophil transepithelial m

129 In a HCC/hepatocyte co-culture model, in which cancerous and healthy cells s

130 ed in a primary human hepatocyte (PHH) based co-culture model, suggesting bidirectional communication

131 Here, 2D culture and 3D mono- and stromal co-culture models of increasing complexity have been est

132 786-0/human umbilical vein endothelial cell co-culture models.

133 resistance and reverts their toxicity toward co-cultured motor neurons.

134 o declining PHH monocultures, micropatterned co-cultures (MPCCs) of PHHs and 3T3-J2 murine embryonic

135 This study developed novel methods to co-culture neural stem cell-derived spiral ganglion-like

136 es, boosting their neuroprotective action in co-cultured neurons.

137 We used floating liquid marbles to co-culture OECs with Schwann cells and astrocytes which

138 Co-culture of 231BR-EGFP cells with E2-treated astrocyte

139 imple, user-friendly microfluidic device for co-culture of a 3D breast tumour model and a 2D endothel

140 Co-culture of activated macrophages with MLE12 epithelia

141 Co-culture of activating tumour cells with fibroblasts r

142 Co-culture of damaged RPE with macrophages leads to the

143 This showed that co-culture of different parasites did not affect their r

144 f bacterial cells in a monoculture, and in a co-culture of E. coli and HEK 293T cells, while leaving

145 In conclusion, direct co-culture of esophageal squamous cell carcinoma and fib

146 iX, human-microbial crosstalk), which allows co-culture of human and microbial cells under conditions

147 In addition, we show that the co-culture of human epithelial cells with the obligate a

148 We have established a robust co-culture of human pancreatic islet microtissues and li

149 The approach capitalizes on co-culture of immune cells from the same patient blood s

150 Co-culture of LECs with TH2 cells also inhibits tube for

151 Co-culture of Leishmania with Peritoneal Mast Cells (PMC

152 detection rate was significantly enhanced by co-culture of leukocytes with cell lines prior to molecu

153 We found that co-culture of macrophages infected with esxL-expressing

154 Co-culture of macrophages with damaged RPE also elicits

155 Collectively, our studies show that 3D co-culture of mESC-CMs with embryonic CFs is superior to

156 is' circuits capable of maintaining a stable co-culture of metabolically competitive Salmonella typhi

157 Co-culture of MM cells with patient bone marrow stromal

158 Furthermore, co-culture of Ncad+ with Ecad+ cells did not promote a '

159 We employed a co-culture of neonatal ventricular myocytes and sympathe

160 In vitro co-culture of primary RGCs with leukocytes resulted in i

161 Using a co-culture system, we found that co-culture of QSG-7701 (human hepatocyte) with HepG2 (he

162 Co-culture of stress-treated DC with mononuclear cells a

163 s can be used to predict the metabolism of a co-culture of the isolates.

164 SC-derived spinal motorneurons and show that co-culture of these cells with human myoblast-derived sk

165 ng seventeen basidiomycetes, among which the co-culture of Trametes versicolor and Ganoderma applanat

166 dic tumor microenvironment (bMTM) comprising co-culture of tumor and endothelial cells in a 3D enviro

167 Furthermore, heterogeneous co-culture of tumour and endothelial cells demonstrated

168 Further investigations demonstrated that co-culture of wild-type and aneuploid ES cells or supple

169 gnificantly increased levels of MIP-1beta in co-cultures of B and NK cells.

170 capacity, we measured interferon-gamma from co-cultures of DCs and autologous Mtb antigen-specific C

171 Cytokines produced by co-cultures of DCs from infected mice and ovalbumin-spec

172 Furthermore, co-cultures of KYSE-410 cells and cancer-associated fibr

173 al. recently demonstrate in Science that 3D co-cultures of mouse ESCs and trophoblast stem cells sel

174 When these proteins were applied to the co-cultures of MSNs and alpha1/beta2/gamma2-expressing H

175 We recapitulated this finding in co-cultures of murine PSCs and PDA organoids, and demons

176 Here, we report the co-culturing of ARMAN-2-related organism, Mia14, with Cu

177 Notably, 3D co-culturing of TDECC cells with TDFSM cells provoked th

178 -methylumbelliferone abrogated the effect of co-culture on Ccl5 in CAF.

179 -mesenchymal stem cells and macrophages when co-cultured on hydroxyapatite-coated poly(lactic-co-glyc

180 induced apoptosis in the presence of stromal co-culture or cytoprotective survival signals.

181 Co-culturing P301S tau-expressing neurons with E4-expres

182 In general, the described co-culture platform provides a powerful tool to discover

183 creening-ready three-dimensional organotypic co-culture platform.

184 s metabolic derivatives were sufficient, for co-culture preference.

185 Preference correlated with three emergent co-culture properties: ethanol catabolism, a distinct vo

186 After stromal co-culture, PS34CD45(-) cells give rise to all blood lin

187 rtholysis' design dramatically increases the co-culture rate from 0% to approximately 80%.

188 Organotypic co-cultures represent an easy, affordable and scalable m

189 The co-cultures reveal that both mouse and human disialosyl

190 ncy when P. aeruginosa/Staphylococcus aureus co-culture RNA samples were tested.

191 s and endothelial cells in three-dimensional co-culture self-assembled into microvessels, and platele

192 ngi-fungi symbiotic systems were built up by co-culturing seventeen basidiomycetes, among which the c

193 The co-cultures showed cooperative interactions and revealed

194 l response, which is distinct from that of a co-culture solely comprising LGG.

195 Co-culturing studies showed that metabolism of yeast man

196 ve liver microenvironment through the use of co-cultures, surface coatings and 3D spheroids.

197 Here, we present a novel microfluidic co-culture system and establish mild, moderate and sever

198 ficantly greater growth benefit to PSCs in a co-culture system as compared with the MYB-silenced cell

199 We deployed an in vitro co-culture system based on direct contact of cancer cell

200 This primary cell-based co-culture system combined with microOCT imaging offers

201 A co-culture system consisting of a polarized mucosal epit

202 In contrast, the transwell co-culture system displays comparatively low levels of B

203 ablish a self-assembling, primary hepatocyte co-culture system that can be infected with patient-deri

204 In this study, we employed a microfluidic co-culture system to recreate important interactions in

205 In this study, a co-culture system was developed for innervation of intra

206 or PDGF-BB in vasculogenesis in the 3D MM/UB co-culture system was validated by direct interference w

207 the first primary human macrophage-enteroid co-culture system, defined conditions that allow for a p

208 that in an osteoblast/bone marrow macrophage co-culture system, immobilization of OPG by HS at the os

209 inal cord neuron-oligodendrocyte myelinating co-culture system, we demonstrate that disruption of dyn

210 Using a co-culture system, we found that co-culture of QSG-7701

211 educed complexity in vitro macrophage-T cell co-culture system, we show that macrophage arginase-1 is

212 ays in a self-assembling, primary hepatocyte co-culture system.

213 neighbors but inhibited by grass neighbor in co-culture system.

214 and macrophages (J771.A1) using a Transwell co-culture system.

215 ually responds to activated macrophages in a co-culture system.

216 ion significantly impairs myelination in our co-culture system.

217 erimentally in a novel parasite-erythrocytes co-culture system.

218 However, established co-culture systems involve brain endothelial cells, astr

219 In co-culture systems, BMFs secreted high levels of murine

220 In co-culture systems, MFs secreted high levels of IL-6, wh

221 Using ELISA and AXIS co-culture systems, we demonstrate that C5aR is critical

222 nt differences were observed between the two co-culture systems.

223 g the interplay of Th1 and Th2 cells through co-culture, Th2-derived IL-4 promoted IL-10 expression b

224 We also found that after co-culturing the dKO-nmMSCs with dKO-MPCs, the myogenic

225 in both CD4(+) and CD8(+) transgenic T cell co-cultures, the expanding CD8(+) T cells differentiated

226 idual NPC cell fractions from rat livers and co-culture them in a transwell format incorporating prim

227 ansferred to healthy donor memory B-cells by co-culturing these cells with plasma from cirrhotic pati

228 iour of microglial cells in primary neuronal co-cultures through the addition of cyclosporine A, a po

229 aining wild type counterparts in an in vitro co-culture titration experiment.

230 osophila prefers a Saccharomyces-Acetobacter co-culture to the same microorganisms grown individually

231 enic CD4(+) T cells from syngeneic mice were co-cultured to assess antigen presentation and T cell ac

232 In order to exploit co-cultures to address other clinically relevant problem

233 Myelinating co-cultures using human induced pluripotent stem cell-de

234 Transport of nanorods across the intestinal co-culture was also significantly higher than spheres.

235 rent time points in the first 48 hours after co-culture was established.

236 te-mediated apoptosis of cancer cells during co-culture was markedly increased in the presence of eit

237 ltured and preserved ex vivo for 35 days and co-culturing was performed with C. parvum.

238 metabolic changes in astrocyte-spinal neuron co-cultures, we carried out metabolomic analysis by (1)H

239 HUVEC: PMN co-cultures were perfused for additional 15 minutes with

240 Primary human osteoblast/osteoclast co-cultures were seeded onto Ti substrates with TiO2 nan

241 Physiological responses to co-culturing were reflected in a quantitative change in

242 coli and jejuni were reduced during pure or co-culture with a beta-glycoside-hydrolysing Parabactero

243 onstrate that this strategy is beneficial in co-culture with a competing PVDPAO1 -producer, P. aerugi

244 In contrast, P. aestuarii does not grow in co-culture with a G. sulfurreducens mutant lacking a tra

245 f mESC-CMs with embryonic CFs is superior to co-culture with adult CFs for in vitro generation of fun

246 ike cells by exposure to defined factors and co-culture with astrocytes.

247 Co-culture with CD8(+) T cells upregulates NCC in mouse

248 ession of PD-1 in NK cells was induced after co-culture with cisplatin-resistant cells.

249 ts potential as a drug delivery platform via co-culture with human cancer cells in vitro.

250 d CYP3A4 activity/albumin synthesis) when in co-culture with human vascular endothelial cells (HUVECs

251 ed in HUVEC-conditioned medium and in direct co-culture with HUVECs.

252 Organoids maintained in co-culture with ISMCs express robust numbers of surface

253 ffector T cell proliferation was enhanced by co-culture with mast cells, but in the presence of disod

254 ealthy mice following culture with CM-MSC or co-culture with MSCs.

255 en (Ag)-specific IFN-gamma production during co-culture with naive transgenic TCR DO.11.10 T cells in

256 n of 3-methyl-2-oxovalerate were observed in co-culture with only SOD1(G93A) neurons while glutamate

257 nd jejuni during pure culture but did during co-culture with P. distasonis or during mixed culture wi

258 ogical barriers and induced enhanced leak in co-culture with PAECs.

259 nditioned medium promotes MM growth, whereas co-culture with preadipocytes results in enhanced MM cel

260 cheaters) enjoy a large fitness advantage in co-culture with producers (cooperators) and spread to hi

261 er the phenotype of KYSE-410 was affected in co-culture with SF and whether Has2 knockdown in SF had

262 intestinal epithelial cells following their co-culture with the commensal Lactobacillus rhamnosus GG

263 rium animalis subsp. lactis (BB 12); and QC, co-culture with the three probiotic microorganisms.

264 n of Reactive Oxygen Species (ROS) by MCs on co-culture with these species of Leishmania which may co

265 he induction of their dormancy when they are co-cultured with a pre-osteoblastic cell line, MC3T3-E1.

266 cancer-associated myofibroblasts (TDFSM) was co-cultured with a pure rat cholangiocarcinoma cell stra

267 Protein profiling of S. parasanguinis co-cultured with A. actinomycetemcomitans revealed a sig

268 OEs co-cultured with ADPCs supplemented with BMP7 and EREG e

269 ole of AE3 in pHi homeostasis in HC neurons, co-cultured with astrocytes.

270 Thailand was co-cultured with B. pseudomallei and production of IL-10

271 Next, ASCs isolated from rats were co-cultured with DP spheres by different assembling appr

272 Human oral epithelial cells (OEs) were co-cultured with either human dental mesenchymal/papilla

273 Neurons co-cultured with EKO glia showed the greatest viability

274 ell aggregates were cultured individually or co-cultured with endothelial cells.

275 ction of freshly isolated T cells or T cells co-cultured with FRCs compared with those cultured witho

276 d into naive mice and their splenocytes were co-cultured with fresh OVA-loaded DCs.

277 ctor T-cells (Teff), when CD4(+) T-cells are co-cultured with GM-CSF derived bone marrow dendritic ce

278 in the migration ability of MDA-MB-231 cells co-cultured with HMEpiC cells was relative to the increa

279 stinal stem cell-derived enteroid monolayers co-cultured with human monocyte-derived macrophages were

280 Model 2 is a system of gastric organoids co-cultured with immortalized stomach mesenchymal cells

281 t begin biliary differentiation program when co-cultured with injured hepatocytes.

282 ng neuronal survival and synaptogenesis when co-cultured with iPSC-derived neurons with APOE epsilon4

283 eoblasts and TRAP activity in RAW264.7 cells co-cultured with MC3T3-E1 cells were assayed.

284 When co-cultured with MDSCs from SS/SS patients, antigen-driv

285 Further, human T-cells co-cultured with miRNA transfected dendritic cells secre

286 ell system in which HE-iPSCs were separately co-cultured with MSCs and/or HUVECs.

287 fected by CM-MSC but reduced when cells were co-cultured with MSCs.

288 th a smoother and more circular surface when co-cultured with osteoblasts.

289 y increased in murine peritoneal macrophages co-cultured with PbANKA-infected red blood cells in vitr

290 e protected from VC-mediated cell death when co-cultured with physiologically relevant numbers of ery

291 iled to support the clonal formation of SSCs co-cultured with SCSKO Sertoli cells.

292 tumor necrosis factor-alpha (TNF-alpha), or co-cultured with T cells.

293 and neonatal spermatogonia (including SSCs) co-cultured with T-treated PM cells were able to coloniz

294 in cancer-associated fibroblasts (CAFs) when co-cultured with the tumor cells.

295 , abolished their increased proliferation in co-cultures with E2-treated astrocytes and decreased bra

296 first time long-term and stable myelinating co-cultures with human neurons.

297 Secondly, we analyzed co-cultures with human peripheral blood mononuclear cell

298 del neuromuscular disease we incubated these co-cultures with IgG from myasthenia gravis patients and

299 3A) expression in all co-cultures, but while co-cultures with only SOD1(G93A) neurons had lower extra

300 Culture of primary DCs or DC and T cell co-cultures with PHCCC NPs reduced DC activation and sec