ライフサイエンスコーパス: coactivate

1 s were blocked when the other AR subtype was coactivated.

2 tion, cNkx-2.8 and serum response factor can coactivate a minimal cardiac alpha-actin promoter.

3 h Gal4-VP16 and EBNA1 strongly activated and coactivated a Gal4-VP16- and oriP-dependent promoter tha

4 The binary agonist MRS 1741 coactivated A(1) and A(3) receptors simultaneously, with

5 ranscriptional coactivator that binds to and coactivates a variety of transcription factors (TFs) to

6 t regulates a broad array of target genes by coactivating a whole host of transcription factors.

7 However, when coactivated, A-neuron posture dominates, limiting B-neur

8 TTP expression attenuates the coactivating activity of SRC-1, suggesting that exchange

9 ta(42) as well as Abeta(40), and appeared to coactivate alpha-, beta- and gamma-secretases, which are

10 bility of class I-restricted CD8+ T cells to coactivate and polarize DCs may support the induction of

11 Vav3 coactivates AR in a Vav3 pleckstrin homology (PH) domain

12 ctivity >1 Hz yielded two larger clusters of coactivated areas with an enlarged default mode network-

13 anterior cingulate cortex (ACC) are commonly coactivated as revealed by a meta-analysis, 2) AIC is fu

14 More importantly, when coactivated at different frequencies, the two commands p

15 PARP-1 coactivated B-Myb- and c-Myb-mediated transactivation of

16 ctional antagonist muscles, TA and Sol, were coactivated both in stimulated rats and in unstimulated

17 azetidine or the proteasome inhibitor MG132 coactivates both HSFs to different levels and hemin pref

18 In this study, we show that SNURF coactivates both wild-type estrogen receptor alpha (ERal

19 ts such as rosiglitazone and ciglitazone, is coactivated by 9 cis-retinoic acid and is inhibited by t

20 en connected over long distances, which were coactivated by a diverse range of experimental tasks.

21 Olfactory cortical neurons coactivated by a specific pattern of odorant evoked inpu

22 TRPM2 channels are coactivated by binding of intracellular ADP ribose and C

23 Furthermore, ERK1/2, when only coactivated by both IP3/Ca2+- and Homer1b/c-dependent pa

24 E2AD2 was specifically coactivated by EBNALP.

25 ereotyped combinations of glomeruli that are coactivated by odors, and certain combinations of glomer

26 promoter and activate it, predominantly when coactivated by PGC-1alpha.

27 hat function robustly only when HNF4alpha is coactivated by PGC-1alpha.

28 ation of Pdk4 transcription by PPARdelta was coactivated by PGC-1alpha.

29 in a failure of YY1 to interact with and be coactivated by PGC-1alpha.

30 d a Cl(-) channel in the transporter that is coactivated by protons and Cl(-).

31 homeobox gene) and either Hoxa7 or Hoxa9 are coactivated by retroviral integration in BXH2 murine mye

32 tral, and default-mode modules predominantly coactivated by specific cognitive domains (perception, a

33 NH(2)/COOH-terminal interaction and was not coactivated by SRC-1.

34 t various subsets of these components can be coactivated by stimulating the same area.

35 creased expression of oncomiR-3151, which is coactivated by the SP1/NF-kappaB complex.

36 e mechanism by which beta-catenin and TCF-4N coactivated C/EBPalpha appeared to involve p300, based u

37 (+)CD25(-) T cells is suppressed in vitro by coactivated CD4(+)CD25(+) T cells.

38 It also coactivates certain non-E2F transcription factors and pr

39 ng module (DUBm) of the SAGA transcriptional coactivating complex, as a SIRT1-interacting partner.

40 rgic synapses can be scaled in accordance to coactivated convergent glutamatergic input.

41 An entrainment stimulus causes CRTC1 to coactivate CREB, inducing the expression of Per1 and Sik

42 p300 and/or CBP (p300/CBP) also coactivate CREB.

43 leukin-12 (IL-12) appears to be an essential coactivating cytokine for hepatic IFN-gamma expression.

44 Finally, the data indicate that compression coactivates distinct signaling pathways that may help de

45 and prefrontal cortex (PFC) are believed to coactivate during goal-directed behavior to identify, se

46 , while frontal and parietal areas typically coactivate during VSTM, maintenance of content in the fr

47 characterize two distinct networks typically coactivated during functional MRI tasks.

48 These sites are often coactivated during neuroimaging studies using semantic t

49 tion (1) scaled the amplitudes of two bursts coactivated during the initial phase of wiping independe

50 (SMA) and the primary motor cortex (PMC) are coactivated during various breathing tasks.

51 1alpha interaction domain, was sufficient to coactivate EBNA2 in a gene-specific manner independent o

52 mphoma cells, we found that EBNA-LP strongly coactivated EBNA2 stimulation of LMP-1 and LMP2B RNAs, w

53 huttling in the heterokaryon assay yet still coactivates EBNA2 similarly to the smaller EBNA-LP isofo

54 ator of EBNA2 targets, but it preferentially coactivates EBNA2 stimulation of the viral divergent pro

55 The independent and coactivating effects of LPS were blocked by anti-TNF-alp

56 erminal (amino acids 576-1566) significantly coactivate ERalpha.

57 inding protein (TBP) and SNURF cooperatively coactivated ERalpha-mediated transactivation.

58 rogen responsive elements (pERE(3)), DRIP205 coactivates ERalpha-mediated transactivation.

59 ansfection studies, DRIP205Delta587-636 also coactivates ERalpha.

60 l3 was shown to synergize with PGC-1alpha to coactivate ERRalpha.

61 Expression of PGC1A in H2.35 cells coactivated estrogen receptor 1 and was required for est

62 On the other hand, SORBS3 coactivated estrogen receptor alpha signaling, leading i

63 lation activity independently are capable of coactivating Ets-2.

64 y if it is assumed that hypertonic infusions coactivate excitatory and inhibitory synaptic inputs.

65 A proportionality or balance between coactivated excitatory and inhibitory inputs is often ob

66 nding endogenous activator protein, Gcn4, to coactivate expression of chromosomal reporter genes in S

67 anterior cingulate cortex (ACC) are commonly coactivated for cognitive saccade tasks, but whether thi

68 site and recruits Fhl3 to transcriptionally coactivate Foxk1 gene expression.

69 It also coactivates from the herpes simplex virus ICPO promoter

70 n their previously described transcriptional coactivating function, our study defines a switch in the

71 domains (TAD) play essential roles for their coactivating function.

72 ion factors in Saccharomyces cerevisiae that coactivate genes necessary for growth in the absence of

73 epends on the ratio between the magnitude of coactivated glutamatergic and GABAergic inputs (E/I rati

74 as shown to physically interact and potently coactivate hepatic nuclear factor 4 and peroxisome proli

75 s inability to physically associate with and coactivate hepatic nuclear receptor 4alpha (HNF4alpha) a

76 RBPJ repressive complexes from enhancers to coactivate hes1 and arglu1 but not cd21 or cd23.

77 p220(NPAT), a substrate of cyclin E/CDK2, to coactivate histone genes during S phase.

78 ide evidence that opponent social categories coactivate in face-processing regions, which compete and

79 k of frontal and parietal areas that usually coactivate in studies of working memory.

80 coding Hoxa9 and Meis1 are transcriptionally coactivated in a subset of acute myeloid leukemia (AML)

81 that PKA, MAPK, and MSK1, a CREB kinase, are coactivated in a subset of hippocampal CA1 pyramidal neu

82 addition, Bmi1 and the PI3K/Akt pathway were coactivated in a substantial fraction of human high-grad

83 er, both pathways are frequently found to be coactivated in cancer tissue.

84 When the two signals are coactivated in cells (i.e. tylapx/apx1), a new response

85 f extrinsic and intrinsic tongue muscles are coactivated in conditions of hypoxemia comparable to tha

86 ) intrinsic and extrinsic tongue muscles are coactivated in mild hypoxia, (2) airway occlusion increa

87 e tongue protrudor and retractor muscles are coactivated in response to hypoxia and hypercapnia, and

88 We hypothesized that multiple RTKs are coactivated in these tumors and that redundant inputs dr

89 t, but whether and how these 2 systems, when coactivated in vivo, interact with each other has not be

90 s with the P-TEFb/CDK9 elongation factor and coactivates inducible genes, including HIV-1.

91 gnal for changes in the strength of a second coactivated input.

92 mutation were equivalent in their ability to coactivate integrin alphaIIbbeta3 in a CHO cell system w

93 As these regions frequently coactivate, it has been difficult to disentangle their r

94 ility of DDX5 to interact with RORgammat and coactivate its targets depends on intrinsic RNA helicase

95 DRIP150 coactivates ligand-dependent ERalpha-mediated transactiv

96 transcription factors Foxo1 and Pax5, which coactivated many pre-B cell genes, including Rag1, Rag2

97 urons also elicit the gastric mill rhythm by coactivating MCN1 and CPN2, but the GPR-elicited gastric

98 urons each elicit the gastric mill rhythm by coactivating MCN1 and CPN2.

99 Moreover, p300/CBP coactivates Mi transcriptional activity in a manner depe

100 he cell's regulatory networks, and examining coactivated modules suggests specific instances of cross

101 diated transcription seen in the presence of coactivating molecules and to the action of AR coinhibit

102 esponses of lymphocytes and the influence of coactivating molecules on these signaling processes is n

103 Signals provided by coactivating molecules such as CD4 and CD28 also influen

104 tions, and (c) the participation of specific coactivating molecules.

105 olish the ability of the full-length SRC1 to coactivate MR.

106 recombinant receptors, confirm that ESP7 can coactivate mu-opioid receptors (MOR) and SPRs in vitro.

107 tionale for the selection of KRAS and PIK3CA coactivating mutations in a number of human malignancies

108 For E1A, P/CAF coactivates MYC, whereas both p300 and CBP suppress E1A

109 tes since TRAF1 is unique among the TRAFs in coactivating NF-kappaB with LMP1(1-231), a TRAF2 dominan

110 ivation potentials of Kv4 that occurred upon coactivating NMDAR and group I metabotropic glutamatergi

111 ty and simultaneously blunt this response by coactivating NO synthase (NOS3) to enhance cGMP synthesi

112 n of E6-AP is dispensable for its ability to coactivate nuclear hormone receptors, showing that E6-AP

113 d kinase (ERK) kinase (MEK)/ERK pathway that coactivates one of the immediate targets of mTOR, p70 S6

114 1(WAF1/CIP1) and the ability for AP2alpha to coactivate p21 requires p53.

115 , an HDAC3 binding-deficient SMRT DAD mutant coactivated p53 transcriptional activity.

116 breast cancer invasiveness and metastasis by coactivating PEA3-mediated Twist expression.

117 hrough abrogation of the ability of PGC-1 to coactivate peroxisome proliferator-activated receptor ga

118 e POP-1/TCF beta-catenin binding domain, and coactivates POP-1-dependent transcription.

119 ed to the synapse to release D-serine, which coactivates postsynaptic NMDA receptors together with gl

120 g results, Bcl3 was shown to synergistically coactivate PPARalpha with PGC-1alpha in a manner similar

121 AR gamma coactivator 1 (PGC-1) is capable of coactivating PPARalpha in the transcriptional control of

122 s necessary and sufficient for PGC-1alpha to coactivate PPARgamma in the presence or absence of rosig

123 ability of each of these mutant proteins to coactivate PR or provide ubiquitin-protein ligase activi

124 nputs from different modalities, which, when coactivated, produced enhanced GC firing rates and disti

125 clear antigen (EBNA) leader protein (EBNALP) coactivates promoters with EBNA2 and is important for Ep

126 The coactivating properties of PIASx(alpha) require Elk-1 to

127 To test whether transcriptional coactivating properties were common to the rhesus LCV EB

128 r extracts, we identify the thyroid receptor coactivating protein (TRCp120), DMAP1, and the related M

129 Conditional disruption of the mTOR coactivating protein Raptor in developing mouse B cells

130 al change that allows for the interaction of coactivating proteins necessary for gene transcription.

131 entified including ones found in traditional coactivating proteins such as SRC1, SRC2, TRAP220, TRBP,

132 In the presence of T3, the TR recruits coactivating proteins that both modulate and integrate t

133 placement of corepressors and recruitment of coactivating proteins.

134 ncreased expression of surface MHCII, T-cell coactivating receptors, and key cytokines/chemokine expr

135 lthough they did express ligands for NK cell coactivating receptors, NTB-A and 2B4.

136 performance of a recollection task known to coactivate regions of both networks.

137 There are relatively few materials whose coactivated response has been well-characterized.

138 rtnership and also influence each other when coactivated, resulting in nonadditive cross-inhibitory r

139 cells and Xenopus embryos, Wnt/Fz signaling coactivates Rho and Rac, another GTPase and distinct reg

140 ity of RVE8-LNK interaction, from a synergic coactivating role of evening-expressed clock genes to a

141 ombination of inhibitors targeting all three coactivated RTKs and MEK1 was needed to inhibit prolifer

142 ptional coactivator with PDZ-binding motif), coactivates Runx2-dependent gene transcription while rep

143 The SRA RNA is a non-coding RNA that coactivates several human sex hormone receptors and is s

144 so associates with Dax-1 and synergistically coactivates SF-1 target gene transcription.

145 ns comprises related acetyltransferases that coactivate signal-responsive transcription.

146 hages (Mphi) or dendritic cells (DC) provide coactivating signals for the liver IFN-gamma response in

147 hrough dynamic competition between parallel, coactivated social categories that resolve into a stable

148 A-5 and GATA-6, were equivalent to GATA-4 in coactivating SRE-dependent targets.

149 ered downstream transcriptional responses by coactivating SREBP-1, which subsequently enhanced lipoge

150 ated transcription factor A [Mrtf-a]), which coactivates Srf-responsive genes downstream of Rho GTPas

151 activate STAT3 but the cleaved PC1 tail now coactivates STAT3 in a mechanism requiring STAT phosphor

152 -1 (Src-1) was specifically recruited by and coactivated Stat6 but not the chimeric Stat6 molecules.

153 receptor RNA activator (SRA) is an RNA that coactivates steroid hormone receptor-mediated transcript

154 n requires the Notch intracellular domain to coactivate Su(H)-mediated transcription of the Enhancer-

155 further participation of at least one of the coactivating substances.

156 In conclusion, coactivating TAA-specific CD4(+) T-helper cells with DCs

157 Among the PGC-1 coactivating targets, the expression of estrogen-related

158 tress-induced NKG2D ligands, such as MIC, by coactivating TCR signaling.

159 isoforms of the TFAP2 transcription factor, coactivating TFAP2-dependent transcription.

160 talization of infected B lymphocytes and can coactivate the EBV LMP1 promoter with EBNA2.

161 RNA helicase and stimulated their ability to coactivate the estrogen receptor, thereby potentially co

162 iate domain (TEAD) transcription factors and coactivate the expression of target genes, promoting cel

163 yr also disables the ability of kindlin-2 to coactivate the integrin.

164 Furthermore, EBNA3C m1 and m2 did not coactivate the LMP1 promoter with EBNA2.

165 nd type A (VWA) domain blocks the ability to coactivate the mating-specific MAPK Fus3.

166 For EBNA2, both P/CAF and CBP coactivate the MYC promoter, whereas p300 suppresses EBN

167 ecules that act as transcriptional adapters, coactivate the myogenic basic-helix-loop-helix (bHLH) pr

168 The CAPER proteins coactivate the progesterone receptor in luciferase trans

169 inding defective mutant Nkx2-5pm efficiently coactivated the alphaCA promoter in the presence of SRF

170 SUMO-3, and the SUMO-conjugating enzyme UBC9 coactivated the LMP1 promoter with EBNA2.

171 SRC-2 expression in vitro Furthermore, SRC-2 coactivated the transcription factors GATA-binding prote

172 In tissue culture, PC-TP coactivated the transcriptional activity of Pax3.

173 ranscription factors RBP-Jkappa and PU.1 and coactivates the EBV LMP1 promoter with EBNA-2 in BL2 and

174 E6-AP also coactivates the hormone-dependent transcriptional activi

175 are at least two mechanisms by which EBNA-3C coactivates the LMP1 promoter with EBNA-2.

176 Instead, PGC-1alpha coactivates the orphan nuclear receptor ERR-alpha (oestr

177 These results suggest that BRCA1 selectively coactivates the p53 transcription factor towards genes t

178 SIRT1 deacetylates and coactivates the retinoic acid receptor beta, a known reg

179 PGC-1beta coactivates the SREBP transcription factor family and st

180 teracts with estrogen-bound ERs and strongly coactivates the transcription of target genes in culture

181 in (E6-AP/UBE3A) directly interacts with and coactivates the transcriptional activity of the human pr

182 expression; in addition, PGC-1 binds to and coactivates the transcriptional function of NRF-1 on the

183 directly regulate Mfn1 gene transcription by coactivating the estrogen-related receptor alpha on a co

184 w find that EBNA-3C is similar to EBNA-LP in coactivating the LMP1 promoter with EBNA-2 in non-EBV-in

185 expression, in large part, by binding to and coactivating the muscle-selective transcription factor M

186 Coactivating TLR2 reduced the injurious effects of decti

187 and detection assay, that HSF1 and HSF2 are coactivated to different levels in response to a range o

188 Chameau and MBF1 cannot synergistically coactivate transcription due to competitive interactions

189 cells, P300 and CBP (but not PCAF) can also coactivate transcription mediated by the EBNA2 or VP16 a

190 activity of ErbB4, repressing its ability to coactivate transcription with Yes-associated protein.

191 kappaB inhibitors because it can function to coactivate transcription.

192 Moreover, whereas p68 robustly coactivated transcription from an estrogen response elem

193 A catalytically inactive topo I, which coactivated transcription, similarly stimulated the rapi

194 ata strongly support a model in which EBNALP coactivates transcription by relocalizing HDAC4 and 5 fr

195 that ectopic overexpression of TRAP220/MED1 coactivates transcription from the Aurora-A gene promote

196 , both represses transcription from P(A) and coactivates transcription from the divergent P(R).

197 In addition, CoAA potently coactivates transcription mediated by multiple hormone-r

198 tly guides phyA to target gene promoters and coactivates transcription.

199 potential combinations of candidate factors, coactivating transcription factors Pax3 and Zic1 not onl

200 amily, is capable of substituting for Sp1 in coactivating transcription from all three of these promo

201 rial promoters and phage early promoters and coactivating transcription from phage middle promoters.

202 rast to tumors activating SHH but not CXCR4, coactivated tumors exhibited greater expression of Math1

203 Furthermore, SRC-1 was found to coactivate Twist transcription through physical interact

204 hat the protrudor and retractor muscles were coactivated under both conditions.

205 res are resolved through competition between coactivated ventral-temporal cortical representations wi

206 ein 1 promoter in lymphoblasts; EBNALP could coactivate with a deficient mutant EBNA2, EBNA2W(454)T,

207 gion, but either protein can synergistically coactivate with pX.

208 and CRP, suggesting that CRP could not fully coactivate with RhaS.

209 on to similar levels, CRP cannot effectively coactivate with RhaS.

210 specific: Sadness and anxiety-emotions that coactivate with shame-fail to track devaluation.

211 EBNA-3C can also coactivate with the EBNA-2 acidic activating domain; thi

212 ility was only modestly increased in T cells coactivated with anti-CD3 and anti-CD28 at 5 h and not i

213 isoforms of NFX1 were found: NFX1-123, which coactivated with c-Myc at the hTERT promoter, and NFX1-9

214 more, EBNA3C amino acids 476 to 992 potently coactivated with EBNA2 but EBNA3C amino acids 516 to 922

215 Marshall nerve activity were preceded by or coactivated with ECNA (stellate ganglion nerve activity

216 Depending on the receptor complex, Tyk2 is coactivated with either Jak1 or Jak2, but a detailed mol

217 We found a group of neurons that were coactivated with extensors during PLRs before RS and exh

218 potentiation at thalamoreticular inputs when coactivated with GluN2B-containing NMDA receptors, which

219 resent study, we explored molecular pathways coactivated with Gro-1/KC, and identified a transcript t

220 k-related increases, either independently or coactivated with other regions in the network.

221 In cases of AML where MET is coactivated with other tyrosine kinases, such as fibrobl

222 emporal order in which the parallel fiber is coactivated with the climbing fiber input, but how order

223 -regulate expression of p27(Kip1), even when coactivated with the Janus kinases (Jak) or the Raf/Erk

224 nscription coactivator p300/CBP binds to and coactivates with both p53 and p73 in stimulating the exp

225 Results also demonstrate that LIPC coactivates with dissociable posterior regions depending

226 Furthermore, this brain area strongly coactivates with other reward-associated regions identif

227 as associated with VR reduction only when it coactivates with the IVC-IAGPNA.