ライフサイエンスコーパス: coactivator

1 hila eye development is as a transcriptional coactivator.

2 chanism by which G9a functions as an ERalpha coactivator.

3 scoordinating Lewis acid TiCl4 or SnCl4 as a coactivator.

4 sting a non-redundant GRIP1 function as a GR coactivator.

5 triggered by the combination of acid and ion coactivators.

6 lated through recruitment of transcriptional coactivators.

7 pathways under the control of this system of coactivators.

8 cations concerning the recruitment of ADs to coactivators.

9 and cytoskeleton-regulated Smad3-interacting coactivators.

10 "first-in-class" drugs that target oncogenic coactivators.

11 crosstalk between early- and late-recruited coactivators.

12 nding protein (CREB)-regulated transcription coactivator 1 (CRTC1) by associative learning in physiol

13 ously unappreciated role of Steroid receptor coactivator 1 (SRC1) in defining the lineage decision fo

14 tein binding protein (CBP), steroid receptor coactivator 1 (SRC1), and protein arginine methyltransfe

15 expression of peroxisome proliferator gamma coactivator 1 alpha (PGC-1alpha).

16 xisome proliferator-activated receptor gamma coactivator 1 alpha (PGC1alpha) were investigated only i

17 melanocortin 2 receptor (MC2R), MC3R, PPARG coactivator 1 alpha (PPARGC1A), and tumor necrosis facto

18 ROR-gamma recruits nuclear receptor coactivator 1 and 3 (NCOA1 and NCOA3, also known as SRC-

19 xisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1alpha), a critical transcripti

20 xisome proliferator-activated receptor gamma coactivator 1-alpha (PGC-1alpha).

21 xisome proliferator-activated receptor-gamma coactivator 1-alpha (PGC1alpha) is the primary regulator

22 Peroxisome proliferator-activated gamma coactivator 1-alpha (PGC1alpha) regulates energy metabol

23 xisome proliferator-activated receptor gamma coactivator 1-alpha (PPARGC1A), a coactivator of the tra

24 xisome proliferator-activated receptor gamma coactivator 1-alpha, and constitutive androstance recept

25 xisome proliferator-activated receptor-gamma coactivator 1-alpha, peroxisome proliferator-activated r

26 isome proliferator-activated receptor gamma, coactivator 1-alpha.

27 xisome proliferator-activated receptor-gamma coactivator 1-beta, nuclear respiratory factor-1, and tr

28 xisome proliferator-activated receptor-gamma coactivator 1.

29 al coactivartor CREB-regulated transcription coactivator-1 (CRTC1) is required for efficient inductio

30 xisome proliferator activated receptor gamma coactivator-1 (PGC-1)).

31 ires co-activators, such as steroid receptor coactivator-1 (SRC-1), to facilitate the transcription o

32 xisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) expression were decrease

33 isome proliferator activated receptor gamma, coactivator 1alpha (PGC-1alpha) is a unique stress senso

34 xisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha) together with estrogen-r

35 xisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha), and fewer mitochondria

36 xisome proliferator-activated receptor gamma coactivator 1alpha (PGC-1alpha).

37 ession of the transcription factor PPARgamma coactivator 1alpha (PGC-1alpha, encoded by Ppargc1a).

38 xisome proliferator-activated receptor gamma coactivator 1alpha (PGC1alpha) controls BAT-mediated the

39 xisome proliferator-activated receptor gamma coactivator 1alpha (PGC1alpha) coordinates the exercise-

40 xisome proliferator-activated receptor gamma coactivator 1alpha (PGC1alpha) serves as a unique adapto

41 xisome proliferator-activated receptor gamma coactivator 1alpha (PGC1alpha), cyclic AMP-responsive el

42 ells showed a progressive loss of PPAR-gamma coactivator 1alpha (PGC1alpha), which programs mitochond

43 roliferator-activated receptor-gamma (PPARG) coactivator 1alpha (PPARGC1A or PGC1A) is inversely corr

44 xisome proliferator-activated receptor gamma-coactivator 1alpha (PPARGC1A) into myonuclei.

45 reased proliferator-activated receptor-gamma coactivator 1alpha expression contributes to the metabol

46 d that proliferator-activated receptor-gamma coactivator 1alpha overexpression in cardiac cells was a

47 ion of proliferator-activated receptor-gamma coactivator 1alpha, a key regulator of fatty acid metabo

48 xisome proliferator-activated receptor gamma coactivator 1alpha.

49 xisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1a) expression that is crucial t

50 xisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1a), which mediates mitochondria

51 xisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha) expression.

52 xisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha) gene, a master regulator

53 xisome proliferator-activated receptor gamma coactivator-1alpha (PGC-1alpha).

54 xisome proliferator-activated receptor gamma coactivator-1alpha expression.

55 xisome proliferator-activated receptor gamma coactivator 1beta (PGC-1beta) and PGC-1alpha-related coa

56 ivated receptor gamma (PPARgamma), PPARgamma coactivator 1beta (PGC1beta), and lipoprotein lipase (LP

57 xisome proliferator-activated receptor gamma coactivator 1beta (PGC1beta).

58 mice; while, compensatory increases in PPARG coactivator 1beta could prevent oxidative damage associa

59 nto a sequence derived from steroid receptor coactivator 2, which interacts with estrogen receptor al

60 e transcriptional regulator steroid receptor coactivator-2 (SRC-2) controls activation of several key

61 ty than to the coactivator, nuclear receptor coactivator-2 (Tif2), in coregulator peptide recruitment

62 The steroid receptor coactivator 3 (SRC-3) is overexpressed in a wide range o

63 eening to identify SMIs for steroid receptor coactivator-3 (SRC-3 or AIB1), a large and mostly unstru

64 ylation and activity of the Steroid Receptor Coactivator-3 (SRC-3) is reduced upon HER2 inhibition, a

65 ogen receptor (ER) recruits steroid receptor coactivator-3 (SRC-3) primary coactivator and secondary

66 eticulocytes and identified nuclear receptor coactivator 4 (NCOA4) as a critical regulator of termina

67 c iron storage protein, and nuclear receptor coactivator 4 (NCOA4) mediates the autophagic turnover o

68 ein and transcriptional coactivator positive coactivator 4 (PC4/Sub1) is absolutely critical for life

69 This "ordered" recruitment allows different coactivator activities to engage the nuclear receptor co

70 n a SPIN1-dependent manner and dampens SPIN1 coactivator activity in TOPflash reporter assays.

71 nt function of SF3B5 in SAGA's transcription coactivator activity that is separate from its role in s

72 ysiology, recent studies indicate that PGC-1 coactivators also serve important functions in cancer ce

73 with PDZ binding motif) is a transcriptional coactivator and end effector of the Hippo tumor suppress

74 (Eya) is a highly conserved transcriptional coactivator and protein phosphatase that plays vital rol

75 eroid receptor coactivator-3 (SRC-3) primary coactivator and secondary coactivators, p300/CBP and CAR

76 luctuation experiments on cells expressing a coactivator and two nuclear receptors and applied hetero

77 YAP is a transcriptional coactivator and while details of YAP regulation are quic

78 view, we discuss the interplay between PGC-1 coactivators and cancer pathogenesis, including tumor in

79 tion is further modulated by tissue-specific coactivators and corepressors.

80 vation by facilitating hCAR interaction with coactivators and enhancing hCAR nuclear translocation in

81 RDT-that largely function as transcriptional coactivators and play critical roles in various cellular

82 Precise control of CLOCK:BMAL1 activity by coactivators and repressors establishes the approximatel

83 e 1) is a regulatory hub for transcriptional coactivators and repressors that compete for binding and

84 ed EZH2 into the category of transcriptional coactivators and thus raised the possibility of noncanon

85 consists of a kinase cascade, transcription coactivators, and DNA-binding partners.

86 cognize downstream promoter elements, act as coactivators, and interact with nucleosomes.

87 ted CCN1 expression, demonstrating that both coactivators are required.

88 noncoding RNAs (lncRNAs) in transcriptional coactivators are still largely unknown.

89 anscriptome signature includes transcription coactivator, ARID5B, which is known to form a chromatin

90 ivo Collectively, these results identify SRC coactivators as regulators of stem-like capacity in canc

91 Since both coactivators associate with the APC/C through their comm

92 Coactivator associated arginine methyltransferase 1 (CAR

93 Coactivator-associated arginine methyltransferase 1 (CAR

94 PRMT4 or coactivator-associated arginine methyltransferase 1 (CAR

95 BRD4, a widely expressed transcriptional coactivator, belongs to the BET family of proteins, whic

96 ene promoter demonstrated that S1P increases coactivator binding at the canonical transcription facto

97 of CBP, the intrinsically disordered nuclear coactivator binding domain of CREB binding protein (UniP

98 with the AF-2 helix to stabilize the LBD for coactivator binding.

99 LxxLL motif in p85alpha, which binds to the coactivator-binding groove on tRXRalpha and dissociates

100 nd constitutive activity from the N-terminal coactivator-binding site, revealing the structural basis

101 Phosphorylation potentiates GRIP1 coactivator but, remarkably, not its corepressor propert

102 The starvation-inducible coactivator cAMP response element binding protein (CREB)

103 ription by promoting recruitment of the CREB coactivator, cAMP-regulated transcriptional coactivators

104 like capacity in cancer cells and that these coactivators can serve as potential therapeutic targets

105 Here, we report that the transcriptional coactivator CBP/p300 is required to maintain the growth

106 s CH1) domain of the general transcriptional coactivators CBP and p300 to control the transcription o

107 The multi-domain transcriptional coactivators CBP/p300 integrate a multitude of signaling

108 naphase-promoting complex/cyclosome) and its coactivator CDC20 (cell division cycle 20).

109 DK regulatory subunit) controlled loading of coactivator Cdc20 onto APC/C.

110 1, Bub3, and Mad2, associated with the APC/C coactivator Cdc20.

111 oting complex/cyclosome (APC/C) bound to its coactivator, Cdc20.

112 spects of orientation of ADs relative to the coactivator, changes in secondary structure and energeti

113 Adipose triglyceride lipase (ATGL) and its coactivator comparative gene identification-58 (CGI-58)

114 recruitment of the Mediator transcriptional coactivator complex and transcriptional activation, but

115 in this process is the transcription factor/coactivator complex composed of SRF/Mkl1.

116 insights into how the multisubunit Mediator coactivator complex dynamically links enhancer-bound act

117 Mediator is an evolutionarily conserved coactivator complex essential for RNA polymerase II tran

118 The multiprotein Mediator coactivator complex functions in large part by controlli

119 cn5 acetyltransferase (SAGA) transcriptional coactivator complex in Drosophila melanogaster.

120 by the Spt-Ada-Gcn5 acetyltransferase (SAGA) coactivator complex is regulated by a recently discovere

121 tion of a number of critical subunits of the coactivator complex Mediator alters only a few MAPK-resp

122 Mediator is a large coactivator complex that bridges enhancer-localized tran

123 ound a coactivator role of MTA1/c-Jun/Pol II coactivator complex upon the IGFBP3 transcription.

124 rginine methyltransferase activity to the ER-coactivator complex, it also alters the structural organ

125 t also with the H3K4 methyltransferase KMT2D coactivator complex.

126 sociate the repressing complexes and recruit coactivator complexes and RNA polymerase II, thereby ind

127 recruiting transcriptional corepressors and coactivator complexes onto neuroectoderm, mesoderm, and

128 Coactivator complexes SAGA and NuA4 stimulate transcript

129 one in deciphering the mechanism of multiple coactivator complexes.

130 histone methyltransferase Ehmt2/G9a, as a RA coactivator controlling somite symmetry.

131 n factors can recruit p300/CBP, and thus the coactivators could be important for beta-cell function a

132 dual inhibitors depleted the transcriptional coactivator CREB-binding protein from the NF-kappaB comp

133 promotes its association with transcription coactivators CREB-binding protein (CBP) and its paralog

134 IRF3 in the presence of its transcriptional coactivator, CREB-binding protein (CBP).

135 CREB protein prevents its interaction with a coactivator, CREB-binding protein, and subsequently redu

136 oci bound by the neuronal activity-regulated coactivator CREBBP, and we measured enhancer and promote

137 protein (CREB)/CREB-regulated transcription coactivator (CRTC) activation.

138 protein (CREB)-cAMP-regulated transcription coactivator (Crtc) has been shown to promote starvation

139 coactivator, cAMP-regulated transcriptional coactivators (CRTC2).

140 regulation of CREB-regulated transcriptional coactivators (CRTCs).

141 tion of the cAMP- responsive transcriptional coactivators (CRTCs).

142 is its interaction with the transcriptional coactivators cyclic-AMP response element-binding protein

143 hances TIS11b interaction with the decapping coactivator Dcp1a, while preventing phosphorylation at S

144 tones and coregulators such as corepressors, coactivators, DNA-binding factors and PTM modifying enzy

145 irect induction of the PGC-1 transcriptional coactivators, drivers of mitochondrial biogenesis and th

146 ExoU, which may be a mechanism by which this coactivator enhances the phospholipase activity of ExoU.

147 In contrast, additional coactivators failed to support robust HBV replication in

148 t the CSRP2BP histone acetyltransferase is a coactivator for CRP2 that works synergistically with SRF

149 Here, we report that CSRP2BP, a coactivator for CRP2, is a histone acetyltransferase and

150 via a GR-independent pathway by serving as a coactivator for Kruppel-like factor (KLF)4-a driver of t

151 emonstrate that SRC1 functions as a critical coactivator for RORgammat in vivo to promote the functio

152 7 (BRD7) functions as a novel transcription coactivator for Smads in TGF-beta signaling.

153 Histone methyltransferase Dot1L is a coactivator for thyroid hormone receptor during Xenopus

154 Pc-repressive complex 1 (PRC1) purifies with coactivators Fs(1)h [female sterile (1) homeotic] and En

155 only a minor contribution to the long-range coactivator function of Mll3/4.

156 ce of S675 phosphorylation and transcription coactivator function on BIG2 AKAP-C sequence.

157 2 nuclear protein kinase and transcriptional coactivator functions are abolished.

158 ed with the ability of ORF2 to stimulate the coactivator functions of HMGA1.

159 anaphase-promoting complex/cyclosome (APC/C) coactivator genes CDC20 and CCS52B (CDH1 ortholog) are c

160 al complex with transcription factor Sp1 and coactivator GRIP1 in MCF-7 human breast and HepG2 liver

161 The Spindlin family of coactivators has five related members (SPIN1, 2A, 2B, 3,

162 The cellular transcriptional coactivator HCF-1 is required for initiation of herpes s

163 nto how SPIN1 functions as a transcriptional coactivator, here we purified its interacting proteins.

164 Our studies revealed that a beta-catenin coactivator, high-mobility group AT-hook 1 protein (HMGA

165 In the present study, a beta-catenin coactivator, high-mobility group AT-hook 1 protein (HMGA

166 CREB-binding protein, a key transcriptional coactivator in IFN signaling, thereby inducing CREB-bind

167 ylated histones and is a key transcriptional coactivator in mammals.

168 pose Integrator as a crucial transcriptional coactivator in MAPK signaling, which could serve as a do

169 unctions in the nucleus as a transcriptional coactivator in phytochrome signaling to regulate a disti

170 We show that these mutant ERs recruit coactivator in the absence of hormone while their affini

171 that Sp5/8 are gene-specific transcriptional coactivators in the Wnt/beta-catenin pathway.

172 by inactivating mutations directly in GATA4 coactivators, including ARID1A.

173 w that Apc1(WD40) is required to mediate the coactivator-induced conformational change of the APC/C t

174 or AE and a reduced ability to be blocked in coactivator interaction, likely contributing to their re

175 We show that the AD-coactivator interactions are highly dynamic while obeyin

176 rs (EBF2, C/EBPbeta, C/EBPalpha, PPARgamma), coactivator MED1, RNA polymerase II, as well as epigenom

177 ons that abrogated GATA4 interactions with a coactivator, MED12, or by inactivating mutations directl

178 -dependent activation of the transcriptional coactivator megakaryoblastic leukemia 1 (MKL1), which ta

179 and RhoA, one utilizing the transcriptional coactivator myocardin-related transcription factor A (MR

180 asome-mediated turnover of the transcription coactivator NPR1 is pivotal for efficient activation of

181 o PGC1alpha with higher affinity than to the coactivator, nuclear receptor coactivator-2 (Tif2), in c

182 e addicted to the expression of OCT2 and its coactivator OCA-B.

183 din-related transcription factor A, a potent coactivator of ACTA2 Two-dimensional Western blotting co

184 gesting that GDU1 functions as an adaptor or coactivator of amino acid exporter(s).

185 ORF2 and a coactivator of beta-catenin, mastermind-like protein 1 (

186 tenin protein, the essential transcriptional coactivator of canonical Wnt signaling, is significantly

187 mide biogenesis independent of its role as a coactivator of epidermal triglyceride catabolism.

188 HCF1 is known as a transcriptional coactivator of herpes simplex virus (HSV) immediate earl

189 PHD3 is a transcriptional coactivator of HIF-1alpha in nucleus pulposus cells inde

190 tomato (Solanum lycopersicum), HsfA2 acts as coactivator of HsfA1a and is one of the major Hsfs accum

191 In pollen, HsfA2 is an important coactivator of HsfA1a during HSR HsfA2 suppression reduc

192 domain containing 5], is a key transcription coactivator of MHC class I genes.

193 Here we show that Ndfip1, a coactivator of Nedd4-family E3 ubiquitin ligases, is req

194 F-kappaB-induced lincRNA-Tnfaip3 to act as a coactivator of NF-kappaB for the transcription of inflam

195 (NACK), also known as SGK223, is a critical coactivator of Notch signaling and binds to the Notch1 t

196 anscriptional corepressor, it functions as a coactivator of oestrogen-related receptor alpha (ERRalph

197 MRTF), a Rho/actin polymerization-controlled coactivator of serum response factor, drives myofibrobla

198 h as an E3 ubiquitin-protein ligase and as a coactivator of steroid hormone receptors.

199 Specifically, we identify UTX as a coactivator of TAL1 and show that it acts as a major reg

200 controversial whether beta-catenin, a known coactivator of Tcf1, has a role.

201 Here we found that TAZ, a coactivator of TEAD transcription factors of Hippo signa

202 Here we show that G9a functions as a coactivator of the endogenous oestrogen receptor alpha (

203 that integration host factor (IHF) is a key coactivator of the luxCDABE bioluminescence genes that i

204 ndicate that TRBP is a novel transcriptional coactivator of the Notch signaling pathway, playing an i

205 ptor gamma coactivator 1-alpha (PPARGC1A), a coactivator of the transcription factor PPAR-gamma that

206 vage-activating protein (SCAP), an essential coactivator of the transcription factor SREBP and thus o

207 We have previously identified positive coactivator of transcription (PC4), a single-stranded DN

208 identified mutations in the SAGA complex, a coactivator of transcription, which abrogate the ability

209 the nucleus and function as transcriptional coactivators of plant defense genes.

210 in-related transcription factors (MRTFs) are coactivators of serum response factor (SRF)-mediated gen

211 ly primarily on competition for binding with coactivators on an alpha-helix located within the transa

212 nscriptional cofactor that plays the role of coactivator or corepressor, depending on the cell and pr

213 vailable structures of TEADs with or without coactivators or inhibitors and discuss the potential the

214 ndependently of the expression of additional coactivators or transcription factors.

215 diator is a highly conserved transcriptional coactivator organized into four modules, namely Tail, Mi

216 lishing the XPC complex as a transcriptional coactivator, our findings underscore two distinct but co

217 he histone acetyltransferase/transcriptional coactivator p300 to this same region, causing hypo-acety

218 by inhibiting the histone acetyltransferase coactivator p300, preventing the induction of matrix met

219 nactivation of the HIF1alpha transcriptional coactivator p300.

220 -3 (SRC-3) primary coactivator and secondary coactivators, p300/CBP and CARM1.

221 ignaling, and the important steroid receptor coactivator PELP1 was also found to be induced in a HIF-

222 Mechanistically, MPC6 blocked AR coactivator-peptide interaction and prevented AR intermo

223 an active conformation capable of recruiting coactivator peptides and present a detailed analysis of

224 alpha) heterodimer bound to DNA, ligands and coactivator peptides, examined through crystallographic,

225 alpha) heterodimer bound to DNA, ligands and coactivator peptides, which shows that NR quaternary arc

226 roduction, and import of the transcriptional coactivator peroxisome proliferator-activated receptor g

227 nstream targets, Myc and the transcriptional coactivator peroxisome proliferator-activated receptor g

228 ression of the mitochondrial transcriptional coactivator peroxisome proliferator-activated receptor g

229 Here we demonstrate that the coactivator peroxisome proliferator-activated receptor g

230 s of YAP are mediated by the transcriptional coactivator peroxisome proliferator-activated receptor-g

231 toma cell line Huh7, the coexpression of the coactivators peroxisome proliferator-activated receptor

232 in brown adipocytes are the transcriptional coactivator PGC-1alpha and its splicing isoform NT-PGC-1

233 promoting acetylation of the transcriptional coactivator PGC-1alpha to control hepatic gluconeogenesi

234 ANKL induction depended on the transcription coactivator PGC-1beta (peroxisome proliferator-activated

235 xisome proliferator-activated receptor gamma coactivator (PGC)-1alpha as well as attenuated forskolin

236 matin-associated protein and transcriptional coactivator positive coactivator 4 (PC4/Sub1) is absolut

237 and one (rs17590046) in the transcriptional coactivator PPARGC1A were associated with essential trem

238 PGC-1-related coactivator (PRC) has a dual function in growth-regulate

239 tor 1beta (PGC-1beta) and PGC-1alpha-related coactivator (PRC).

240 teraction with its IFN-beta promoter and its coactivator protein (CREB-binding protein).

241 Studies of the estrogen receptor (ER) coactivator protein Mediator subunit 1 (MED1) have revea

242 YAP (Yes-associated protein) is a coactivator protein which, upon binding to TEAD proteins

243 TET2 bound the androgen receptor (AR) and AR-coactivator proteins in LNCaP cell extracts, and TET2 KD

244 ts with both transcriptional corepressor and coactivator proteins, functioning as both a repressor an

245 r molecule for the recruitment of additional coactivator proteins, which can finely regulate HBV tran

246 Coactivators recognize substrate degrons, and enhance th

247 upplies, the PGC-1 family of transcriptional coactivators regulates mitochondrial biogenesis to contr

248 , Hdac1, Hdac2 that act together with RA and coactivator Rere/Atrophin2 and a histone methyltransfera

249 symmetry requires retinoic acid (RA) and its coactivator Rere/Atrophin2.

250 of MTA1 upon IGFBP3 expression, and found a coactivator role of MTA1/c-Jun/Pol II coactivator comple

251 This study reveals a structural role for a coactivator sequential recruitment and biochemical proce

252 Nuclear receptors recruit multiple coactivators sequentially to activate transcription.

253 Yap and Taz are transcription coactivators shuttling from the cytoplasm to the nucleus

254 rylation and activity of the transcriptional coactivator SRC-3.

255 Methoprene-tolerant (Met), steroid receptor coactivator (SRC) and GATAa but not ecdysone receptor (E

256 nscription factor (Met) and steroid receptor coactivator (SRC), would be expressed coincident with th

257 enabling an interaction between VDR and the coactivator, SRC-3 (NCOA3), thereby increasing transcrip

258 erentiation by inhibiting the recruitment of coactivator SRC1.

259 mERbeta2 recruited coactivators SRC2 or SRC3 in the presence of EDCs, but s

260 AR and its steroid receptor coactivators (SRCs; SRC-1, -2 and -3) were recurrently a

261 we show that miR-101 targets transcriptional coactivator SUB1 homolog (Saccharomyces cerevisiae)/PC4

262 degron recognition sites on Cdc20, the APC/C coactivator subunit responsible for substrate interactio

263 tivate transcription and require the help of coactivators such as YAP, TAZ, VgLL, and p160 proteins.

264 cilitated interaction with the TFIID subunit coactivator TAF4 assessed by immunoprecipitation.

265 ed by Pkd1 and Pkd2) and the transcriptional coactivator TAZ form a mechanosensing complex in osteobl

266 tyrosine kinase ABL and the transcriptional coactivator TAZ.

267 Hippo pathway transcriptional coactivators TAZ and YAP and the TGF-beta1 (TGFbeta) eff

268 y of Rap1 binding to a known transcriptional coactivator TFIID-binding target, Taf5.

269 ed to DNA sequence properties and use of the coactivators TFIID or SAGA.

270 matin-modifying complex is a transcriptional coactivator that contains four different modules of subu

271 PGC1alpha is a transcriptional coactivator that promotes mitochondrial biogenesis, prot

272 pha; encoded by Ppargc1a), a transcriptional coactivator that regulates broad programs of fatty acid

273 onents of MAPK signaling, the key downstream coactivators that coordinate the transcriptional respons

274 However, transcriptional coactivators that mediate their developmental function r

275 preciated that p300 acts as a critical Notch coactivator, the mechanistic details of p300 in Notch-me

276 ot1L in turn functions as a T3 receptor (TR) coactivator to promote vertebrate development.

277 e mobilization of the Golgi-localized ARA160 coactivator to the nuclear compartment of prostate tumor

278 ietic-specific transcription factors require coactivators to communicate with the general transcripti

279 tivated transcription, and what dictates its coactivator versus corepressor properties is unknown.

280 by the Spt-Ada-Gcn5 acetyltransferase (SAGA) coactivator, which contains a four-protein subcomplex kn

281 Spindlin1 (SPIN1) is a transcriptional coactivator with critical functions in embryonic develop

282 uced nuclear localization of transcriptional coactivator with PDZ binding motif (TAZ) and Yes-associa

283 associated protein) and Taz (transcriptional coactivator with PDZ binding motif) in tissue developmen

284 TAZ (transcriptional coactivator with PDZ binding motif) is a transcriptional

285 associated protein (YAP) and transcriptional coactivator with PDZ-binding motif (TAZ) are related mec

286 We show that FGF18 induces transcriptional coactivator with PDZ-binding motif (TAZ) expression, whi

287 ociated protein 1 (YAP1) and transcriptional coactivator with PDZ-binding motif (TAZ).

288 associated protein) and Taz (transcriptional coactivator with PDZ-binding motif), as key steps in onc

289 arly (Yes-associated protein/Transcriptional coactivator with PDZ-binding motif, YAP/TAZ) and late (a

290 (EP300) and CBP (CREBBP) are transcriptional coactivators with histone acetyltransferase activity.

291 amily proteins are conserved transcriptional coactivators with intrinsic protein phosphatase activity

292 of co-expressed Cdh1, an E3 ubiquitin ligase coactivator, with reduced ubiquitination, and allowed DN

293 ses Lats1 and Lats2, and the transcriptional coactivators Yap and Taz [4-6].

294 hosphorylate and inhibit the transcriptional coactivators Yap and Taz, in nephron progenitor cells.

295 phorylate and inactivate the transcriptional coactivators YAP and TAZ, which control cell growth and

296 ed the nuclear expression of transcriptional coactivator YAP1 in the limbal and corneal basal epithel

297 show that the Hippo pathway transcriptional coactivators Yap1 and Wwtr1 are specifically localized t

298 SRF) and the other using the transcriptional coactivator Yes-associated protein (YAP) and TEA domain

299 2) control activation of the transcriptional coactivators Yes-associated protein (YAP) and WW domain

300 hat are classic targets of the Hippo pathway coactivator Yorkie.