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1 ediated transcriptional activation through a coactivator function.
2 tion, but it is defective in transcriptional coactivator function.
3 insight into the molecular mechanisms of G9a coactivator function.
4 enhances PKM2 binding to HIF-1alpha and PKM2 coactivator function.
5 the importance of APE1's acetylation in its coactivator function.
6 perties of the TAF4 subunit that lead to the coactivator function.
7 nd has been shown to possess transcriptional coactivator function.
8 y, only a selected subset required BAF57 for coactivator function.
9 sed in terms of our present understanding of coactivator function.
10 nfirmed a critical role for them in in vitro coactivator function.
11 (PPAR)-interacting protein) and enhance its coactivator function.
12 e activity of PRMT2 appeared pivotal for its coactivator function.
13 th other proteins that help to mediate CARM1 coactivator function.
14 significant additive inductive effect on PBP coactivator function.
15 MAPK cascade exerts a positive effect on PBP coactivator function.
16 tion of GRIP1 transcriptional activation and coactivator function.
17 tor HNF4) and thus recapitulates partial USA coactivator function.
18 de a more physiologically relevant assay for coactivator function.
19 DR heterodimers bound to DNA and for TRAP220 coactivator function.
20 with octamer-bound Oct-1 and for subsequent coactivator function.
21 new tool for investigating the mechanism of coactivator function and demonstrates the importance of
22 However, the mechanism of beta-catenin-GRIP1 coactivator function and synergy is different with AR an
26 AR that is capable of altering AR activity, coactivator function, and AR-dependent proliferation.
27 eviously been implicated in nuclear receptor coactivator function, and we show that, although BAF57 f
28 th respect to specific polypeptide subunits, coactivator functions, and mechanisms of action (activat
31 c evidence that this generic transcriptional coactivator functions as a positive modifier of prostate
33 er, our findings suggest that the human CRSP coactivator functions, at least in part, by mediating ac
34 sferase inhibitor UNC0646 did not affect G9a coactivator function but selectively decreased G9a corep
35 icate that phosphorylation coordinates SRC-3 coactivator function by linking the probabilistic format
37 and it has been recently proposed that these coactivators function by modulating chromatin structure
39 Deletion of AD1 only partially reduced p160 coactivator function, due to signaling through AD2, anot
40 tivator binding sites and that dependence on coactivator function for a given activator can vary acco
43 ork identified a stimulatory transcriptional coactivator function for the BRCA1 protein, and more rec
44 m changes in TIP60 complex assembly or TIP60 coactivator functions for p53, since a TIP60 complex con
45 acetyl coenzyme A-dependent transcriptional coactivator functions from a chromatin-assembled templat
46 tional activator and suggest that control of coactivator function (i.e. recruitment of CBP and stimul
47 lized TRbeta LBD depleted the extract of the coactivator function in a triiodothyronine-dependent man
49 plays a role in breast cancer because of its coactivator function in ER signaling, we determined the
50 steine-rich domain) were unnecessary for G9a coactivator function in ERalpha-mediated transcription.
51 d blocks both its enzymatic activity and its coactivator function in regulating basal p21 gene expres
52 re the requirement of ubiquitylation for the coactivator function in regulating HIV-1 transcriptional
53 potent, activator-dependent transcriptional coactivator function in response to VP16, Sp1, and Sp1/S
55 tigate the requirement of lipin-1 PAP versus coactivator function in the establishment of Pparg expre
56 These results strongly suggest that a p160 coactivator functions in CAR-mediated transactivation in
57 insic acetyltransferase activity whose exact coactivator functions in the acetylation of nucleosomal
59 roles in vivo and suggest a new mechanism of coactivator function, in which a single adaptor protein
63 eginning E(2) treatment, suggesting that G9a coactivator function is by direct interaction with ERalp
64 scriptional regulation, suggest that SRCAP's coactivator function may depend on its ability to promot
65 the N-terminal domain and that the increased coactivator function of AIB1-Delta4 is due to the loss o
68 ption activator target that is essential for coactivator function of both the SAGA and NuA4 histone a
71 other domains of CARM1 are required for the coactivator function of CARM1 in addition to the methylt
72 AD, the interaction of CoCoA with p300, the coactivator function of CoCoA for estrogen receptor alph
73 sactivation activity and is required for the coactivator function of CoCoA with nuclear receptors.
74 ding transcriptional activator proteins, the coactivator function of GRIP1 with Lef1 follows a novel
79 n was accompanied by inhibition of the basal coactivator function of PELP1 upon estrogen receptor tra
80 gion of PGC-1alpha abolished the cooperative coactivator function of PGC-1alpha and PRMT1, and compro
81 cted with SRC1 and p300, suggesting that the coactivator function of RIZ1 may be mediated by its inte
83 studies have shown that the transcriptional coactivator function of the Mediator involves direct lig
85 ely to result in differential effects on the coactivator functions of CBP/p300 for different classes
88 on in vivo, we have investigated further the coactivator functions of steroid receptor coactivator-1
91 e previously shown that yeast TFIID provides coactivator function on the promoters of ribosomal prote
96 mmary tumor virus (MMTV) promoters, and this coactivator function required the methyltransferase acti
97 rmone responses in vivo and that loss of its coactivator function results in partial resistance to ho
98 tivator complex but differentially modulates coactivator function such that inhibition of the CBP/p30
101 owever, the molecular basis underlying MAML1 coactivator function that contributes to Notch signaling
102 role for G9a as a molecular scaffold for its coactivator function, the G9a-specific methyltransferase
103 results are in contrast to the classic ARA55 coactivator function to enhance AR transactivation parti
105 GRIP1 mutants deficient in GR binding and coactivator functions were also defective for corepressi
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