ライフサイエンスコーパス: coadministration

1 effect on QT of chloroquine plus tafenoquine coadministration.

2 xL, effects that were abolished by obatoclax coadministration.

3 o increase plasma D-Serine levels after oral coadministration.

4 ncrease in TUNEL positive staining with iRGD coadministration.

5 nduction in hepatic tissue was observed upon coadministration.

6 ulations disappear on agonist and antagonist coadministration.

7 per kilogram, intravenously, 5 min prior) or coadministration (2 mg of (+)-DTBZ per kilogram).

8 linical proof of concept for the use of iRGD coadministration as a strategy to widen the therapeutic

9 antibody responses to HZ/su and IIV4 in the coadministration compared with the control group.

10 prior failure of DAA-containing therapy; RBV coadministration did not improve efficacy.

11 is demonstrated that 5-HT2CR/5-HT1BR agonist coadministration did not significantly potentiate the fi

12 ggered EGFR inhibition, but not simultaneous coadministration, dramatically sensitizes a subset of tr

13 While HMBPP/IL-2 coadministration during acute or chronic phase of SHIV i

14 dministration with levodopa, and (3) chronic coadministration for 1 month.

15 e 5-10 times higher than those observed with coadministration formulations and nonadjuvanted NiNLPs.

16 On coadministration, geometric mean values of midazolam max

17 istent with our in vitro results, teniposide coadministration greatly enhanced fragmented rAAV8 trans

18 total of 413 subjects were vaccinated in the coadministration group and 415 in the control group.

19 were the HZ/su vaccine response rate in the coadministration group and the noninferiority of the ant

20 The HZ/su vaccine response rate in the coadministration group was 95.8% (95% confidence interva

21 followed by a second HZ/su dose at month 2 (coadministration group), or IIV4 at month 0 and HZ/su at

22 Neither cyclosporine nor tacrolimus coadministration had a meaningful effect on boceprevir p

23 Coadministration had minimal impact on DRV maximum obser

24 amic relationships of verapamil and rifampin coadministration in mice.

25 itumor responses were elicited after U-Omp19 coadministration, increasing survival of mice in a murin

26 ing of the treated tumors revealed that iRGD coadministration induced a vesicular transport pathway t

27 Coadministration of 25(OH)D in the context of OVA-specif

28 Coadministration of 3 mg/kg ADX_5322_A02 anti-PD-L1 adne

29 munoprotection could be improved by the oral coadministration of 3 Salmonella carrying the plasmids t

30 ake of either tracer was not affected by the coadministration of 40 nmol ( approximately 5 mg/kg) of

31 Tumor uptake was decreased by the coadministration of 400 mug of unlabeled conatumumab (me

32 nes to treat HR-defective tumors and for the coadministration of 6-TG and allopurinol as an immunomod

33 c potency could be significantly enhanced by coadministration of a 5-HT1BR agonist and whether this w

34 Therefore, coadministration of a 5-HT1BR agonist potentiates the an

35 Coadministration of a bacterial adjuvant with oral immun

36 physema, and this resistance was reversed by coadministration of a beta-catenin inhibitor, suggesting

37 However, coadministration of a blocking anti-VEGF antibody inhibi

38 circadian clock by melatonin was blocked by coadministration of a GIRK channel antagonist tertiapin-

39 d to deliver better synergistic effects than coadministration of a mixture of multiple drugs.

40 In a rat cardiac transplantation model coadministration of a nonefficacious dose of prodrug 14

41 We found, however, that coadministration of a novel emulsome adjuvant, which enh

42 Notably, in a murine model of lung cancer, coadministration of a PI3Kdelta-specific inhibitor with

43 lacebo-controlled trial evaluating the novel coadministration of a probiotic and peanut OIT and asses

44 The studies described herein suggest that coadministration of a PXT-derived agent with cancer chem

45 Coadministration of a PYK2 inhibitor and Na2S did not re

46 Consistent with this result, coadministration of a selective pharmacological inhibito

47 inimum 14-day washout period, and subsequent coadministration of a single 0.5-mg dose of tacrolimus w

48 minimum 8-day washout period, and subsequent coadministration of a single 10-mg oral dose of cyclospo

49 ble solution, we rescued the IgG response by coadministration of a Toll-like receptor 9 agonist, amon

50 ed replication plan of key experiments from 'Coadministration of a tumor-penetrating peptide enhances

51 plicate selected experiments from the paper "Coadministration of a tumor-penetrating peptide enhances

52 preclinical data demonstrate the efficacy of coadministration of adenoviral VEGF and Ang-1 in increas

53 Coadministration of adjuvants enhanced anti-P1 serum ant

54 In addition, we found that coadministration of AdVCA0848 with another adenovirus se

55 Most vaccines depend on coadministration of Ags and adjuvants that activate APCs

56 h retention latencies, which was blocked by coadministration of alpha-helical CRF(9-41), suggesting

57 Coadministration of amifostine decreased renal uptake of

58 a after administration of vancomycin without coadministration of aminoglycosides.

59 in particular when considering the frequent coadministration of aminoglycosides.

60 lower than in wild-type mice, and intranasal coadministration of an anti-C3a mAb with P to P(-/-) mic

61 Furthermore, coadministration of an anti-IL-5 mAb with IL-33 prevente

62 Coadministration of an anti-IL-6 antibody with polyI:C r

63 this drug can be heightened significantly by coadministration of an artificial nucleoside (5-nitroind

64 of rotavirus, a result strictly dependent on coadministration of an effective adjuvant.

65 However, coadministration of an IKKbeta inhibitor may be both nec

66 in-8 (IL-8) from tumors into the plasma, and coadministration of an IL-8 neutralizing antibody resens

67 The coadministration of an ISCOMATRIX vaccine with the TLR3

68 iated, in part, through modulation of OT, as coadministration of an OT receptor antagonist prevented

69 ased food intake, which was blocked by prior coadministration of analogue 3.

70 Coadministration of anti-41BB mAb with TriVax enhanced R

71 In contrast, coadministration of anti-IL-10R and TGF-beta mAbs had li

72 Coadministration of anti-PD-L1 or anti-CTLA-4 singly wit

73 cytokines in recipient mice, especially with coadministration of anti-PD-L1.

74 Coadministration of antigen with rapamycin simultaneousl

75 trong antibody responses in mice without the coadministration of any additional adjuvant by noncovale

76 redictive of clinical response revealed that coadministration of Apo2L/TRAIL with AMG 655 leads to in

77 Inhibition of Nox2 by coadministration of apocynin or diphenyleneiodonium was

78 Moreover, lowering the initial viral load by coadministration of ART and immunotherapy enabled prolon

79 Coadministration of artemether and nimodipine, a calcium

80 ffect of aspirin is peptic ulcers; therefore coadministration of aspirin with a proton-pump inhibitor

81 Furthermore, systemic coadministration of beta-glucan plus pancreatic beta cel

82 These effects were reversed by coadministration of bicuculline.

83 inding in the PD-L1(+) spleen was reduced by coadministration of BMS-986192.

84 Finally, coadministration of BMS354825 and UCN-01 suppressed huma

85 Coadministration of boceprevir with cyclosporine/tacroli

86 Accordingly, coadministration of cabozantinib and MEK inhibitors trig

87 Coadministration of caffeine with a low dose of l-DOPA r

88 However, coadministration of cbp antisense, but not scrambled oli

89 Coadministration of ChABC and plasmin enhanced the tPA(-

90 However, coadministration of cidofovir and Dryvax also reduced va

91 Thus, the single-dose coadministration of cidofovir and Dryvax effectively con

92 All the effects were reverted by coadministration of compound C (9), an AMPK inhibitor, o

93 the human tumor HeLa and PC3 cells, but the coadministration of copper increases the ligands effects

94 Importantly, coadministration of CPA with a human CAR activator led t

95 The coadministration of CPS49 and flavopiridol acts through

96 ma was associated with the number of days of coadministration of CYP3A inhibitors (r=0.30; p=0.006).

97 Furthermore, oral coadministration of D-serine with 11h enhanced the plasm

98 Consequently, coadministration of D-Serine with a DAAO inhibitor has b

99 Coadministration of DA with the broad spectrum excitator

100 Coadministration of DD with IL-15, which binds to IL-2Rb

101 Coadministration of DELT and CLON inhibited the release

102 f platelet function were reduced less by the coadministration of dexlansoprazole or lansoprazole with

103 a post hoc analysis to assess the effect of coadministration of different OPV formulations on RV1 im

104 Furthermore, our data suggested that coadministration of DNA-encoding calreticulin (CRT) link

105 Both monotherapies and coadministration of DNase I and rhADAMTS13 revealed a ca

106 om the baseline by up to 90% (P < 0.0001) by coadministration of DO3A-exendin-4 at 100 mug/kg.

107 p preventive chemotherapy programmes for the coadministration of drugs to target lymphatic filariasis

108 Here we show that coadministration of effector Ab substantially improved t

109 ed WAVE1 dephosphorylation was attenuated by coadministration of either a D1 dopamine receptor or NMD

110 Coadministration of either ATROSAB or EHD2-scTNFR2 into

111 r soluble Abeta levels, effects negated with coadministration of elacridar, a P-gp inhibitor.

112 , dual inhibition of IL-1beta and IL-18, and coadministration of endothelial progenitor cells and str

113 However, coadministration of epiallopregnanolone sulfate with cho

114 Coadministration of ES with VEGF inhibitors may offer a

115 or lansoprazole with clopidogrel than by the coadministration of esomeprazole or omeprazole.

116 Coadministration of eszopiclone and escitalopram was wel

117 Coadministration of excess unlabelled DPA-713 abrogated

118 navir, efavirenz, and tenofovir to guide the coadministration of faldaprevir with these agents in hum

119 Coadministration of flavopiridol and obatoclax synergist

120 In rats, coadministration of FLX (2.5, 5.0, and 10.0 mg/kg) incre

121 Coadministration of FXI ASO with enoxaparin or the antip

122 Coadministration of gadolinium-based contrast and a CCR2

123 ependently of estradiol, and the response to coadministration of genistein and dexamethasone was uniq

124 Coadministration of ghrelin and GH, but not ghrelin alon

125 hamide > 5 g/m(2) (P = .019), but not to the coadministration of GnRHa during chemotherapy (odds rati

126 therapy or tumor burden but was augmented by coadministration of granulocyte-colony stimulating facto

127 However, coadministration of GT with BH(4) did not result in a fu

128 N/OFQ blocked SIA in wild-type mice, while coadministration of Hcrt-1 overcame N/OFQ inhibition of

129 Coadministration of HG-829 fully restored in vivo antitu

130 Notably, coadministration of hhep25 and hemoglobin but not admini

131 Furthermore, we found that coexpression or coadministration of HSP70 from VSV vector significantly

132 Our results suggest that short-term coadministration of HU and Akti XII has immediate benefi

133 microscopy, we demonstrated that short-term coadministration of HU and Akti XII, an AKT2 inhibitor,

134 Coadministration of HUP (50 microg/kg s.c., 15 min befor

135 Coadministration of hypothalamic PKC-delta inhibitor rot

136 The coadministration of ICI 182,780 blocked the effects of D

137 Coadministration of ICI 182,780 or Wortmannin abolished

138 Coadministration of ICT2588 with doxorubicin resulted in

139 We hypothesized that coadministration of IL-12 with a murine anti-HER2/neu mA

140 In contrast, coadministration of IL-13 with a higher dose of IL-17 de

141 However, coadministration of IL-15 with DD could alleviate this p

142 Intratracheal coadministration of IL-17A and TNF-alpha in mice induced

143 osis, and this protection was reversed after coadministration of IL-17A.

144 This effect is significantly increased by coadministration of IL-33 (5-100 ng/mL) in both cell typ

145 der investigation and include the following: coadministration of immunosuppressive and prosurvival ag

146 Coadministration of ineffective lorcaserin (0.1 mg/kg pe

147 rlying signaling mechanisms involved through coadministration of inhibitors of phospholipase C (PLC),

148 In this study, the postoperative coadministration of iNO and oral sildenafil in patients

149 administration in group B improved after the coadministration of iNO, and thus PaO(2)/inspired fracti

150 Coadministration of insulin and FFAs, however, abolished

151 gemcitabine in the mice could be improved by coadministration of IPI-926, a drug that depletes tumor-

152 erefore, supports the WHO recommendation for coadministration of IPTi with sulfadoxine-pyrimethamine

153 In a KRAS-induced orthotopic PDAC model, coadministration of iRGD enhanced the uptake of an irino

154 Thus, coadministration of iRGD may be a valuable way to enhanc

155 Coadministration of IV vancomycin and piperacillin/tazob

156 s of this study clearly demonstrate that the coadministration of key enzyme inhibitors can effectivel

157 Coadministration of KGF with IAV markedly accelerated th

158 ve prediction of DDI risk indicated that the coadministration of lapatinib or imatinib at clinical do

159 Coadministration of lapatinib with obatoclax caused syne

160 Coadministration of lapatinib with obatoclax elicited au

161 ufficient to ameliorate hyperglycemia alone, coadministration of leptin with islet transplantation ro

162 The coadministration of lithium with paclitaxel also allows

163 nd human cancer models in vivo, we show that coadministration of low-dose Cilengitide and Verapamil i

164 ction of tolerance to rhASB was initiated by coadministration of low-dose corticosteroids, rituximab,

165 This effect was completely antagonized by coadministration of luzindole in all groups.

166 Coadministration of LY2828360 (0.1 mg/kg per day i.p. x

167 Coadministration of methadone with antiretrovirals in pa

168 However, coadministration of methylprednisolone acetate results i

169 ral neostriatum compared with TBZ alone, and coadministration of mianserin with TBZ and FLX attenuate

170 counted for these apparent benefits, because coadministration of mifepristone prevented stress-induce

171 Coadministration of monovalent, bivalent, or trivalent O

172 Long-term coadministration of MOR and DOR agonists caused cAMP ove

173 ntestine, as well as niche competition after coadministration of multiple species of the microbiota.

174 oth CYP2J2 and CYP2C8 transgenic mice during coadministration of N-nitro-l-arginine methyl ester and

175 ivity and inhibit neurotransmission, and the coadministration of N-type Ca(2+) channel blocker facili

176 Coadministration of NAC and a nonpeptidic GpIIb/IIIa inh

177 In vivo, coadministration of naive TCR transgenic T cells (2D2 T

178 Coadministration of nanoformulated RIF and INHP provided

179 y ACPD plus kainate cotreatment; rather, the coadministration of NBQX plus LY341495 prevents the fors

180 ation of fear conditioning was attenuated by coadministration of nicotinic antagonist.

181 a production and provide a rationale for the coadministration of NK cell-activating cytokines with th

182 of the tachykinin precursor 1 (Tac1) gene or coadministration of NK1 receptor antagonists produces lo

183 Interestingly, coadministration of NRTN and liraglutide normalized hype

184 Coadministration of NYVAC-KC with the DC-targeting vacci

185 Coadministration of O6-benzylguanine (O6BG) can restore

186 In healthy controls, coadministration of OBV/PTV/r + DSV + darunavir (DRV) lo

187 Coadministration of octreotide LAR and everolimus did no

188 of anti-PD-L1 IgG plus HER2.CAR T cells and coadministration of Onc.Ad in an HER2(+) prostate cancer

189 Coadministration of oral insulin improved and prolonged

190 s with delirium were associated with days of coadministration of P-glycoprotein inhibitor (r=0.35; p=

191 Likewise, the coadministration of PA resulted in a marked increase in

192 In a similar manner, the coadministration of PA resulted in an equally impressive

193 Coadministration of paclitaxel increased the uptake of F

194 Therapeutic effects, however, required coadministration of paired TLR agonists and DC-tumor fus

195 This study evaluated whether coadministration of parenteral iron improves ESA efficac

196 f cisplatin was significantly potentiated by coadministration of PD173074.

197 prior to voriconazole (OR, 6.21; P = .008), coadministration of penicillins (OR, 6.12; P = .03), and

198 In addition, coadministration of PIKA with a poorly immunogenic H5N1

199 Coadministration of pioglitazone with peginterferon/riba

200 Although it is clear that coadministration of poly(I:C) with antigen elicits stron

201 Coadministration of pralatrexate and romidepsin was safe

202 Preadministration and coadministration of probiotics ameliorated C. rodentium-

203 courage the further clinical development and coadministration of protein and viral vector vaccine pla

204 Energy intake during coadministration of PYY(3-36) and oxyntomodulin was redu

205 Finally, coadministration of R115777 diminished UCN-01-mediated E

206 loped for cancer therapy may pose risks with coadministration of radiotherapy.

207 Similarly, coadministration of rapamycin with AAV vectors resulted

208 Moreover, coadministration of rapamycin with L-DOPA counteracts L-

209 -concept study in overweight/obese subjects, coadministration of recombinant human leptin and the amy

210 olimus are affected to a large extend by the coadministration of ritonavir in HIV-infected transplant

211 Coadministration of rizatriptan, a 5-HT(1B/D) agonist an

212 Coadministration of SAHA and olaparib synergistically in

213 Indeed: (1) coadministration of SB216763 and atractyloside (MPTP ope

214 rexcitability by minocycline was overcome by coadministration of sIL-6R, showing that sIL-6R is requi

215 of this study was to examine the effects of coadministration of sildenafil and inhaled nitric oxide

216 We hypothesized that the in vivo coadministration of specific enzyme inhibitors would imp

217 tream mediators of IFN-gamma signaling, upon coadministration of spermidine to IFN-gamma-treated cell

218 oantibodies against HEL was not dependent on coadministration of strong adjuvants, such as CFA.

219 Coadministration of subtoxic or minimally toxic concentr

220 , and that these effects can be amplified by coadministration of sunitinib.Significance: These findin

221 ls can be resensitized to immunotherapy with coadministration of targeted inhibitors to antiapoptotic

222 uated the increase in oral tremor induced by coadministration of TBZ (0.75 mg/kg) with FLX (5.0 mg/kg

223 Consistent with these behavioral data, coadministration of TBZ and FLX decreased DA tissue leve

224 appropriate dose adjustments needed for safe coadministration of telaprevir with cyclosporine or tacr

225 Coadministration of tempol, a superoxide dismutase mimet

226 In both groups, the coadministration of the 2 drugs resulted in a significan

227 Coadministration of the 3D regimen with the evaluated HI

228 neurons in the DRN because it was blocked by coadministration of the 5-HT(1A) agonist 8-OH-DPAT [((+/

229 decreased synaptic GluA1 expression, whereas coadministration of the A1AR agonist inhibited both coca

230 4-triazolo[1,5-c] pyrimidine (SCH58261), and coadministration of the A2AR-specific agonist 2-[p-(2-ca

231 e signal in the brain of mice increased with coadministration of the ABCG2 inhibitors Ko143, gefitini

232 In addition, ICV coadministration of the alpha-MSH antagonist agouti-rela

233 Moreover, coadministration of the CDK4/6 inhibitor palbociclib in

234 ventricular injection of CGRP and blocked by coadministration of the CGRP receptor antagonist olcegep

235 In addition, coadministration of the combination of CRT/E6 DNA with C

236 Coadministration of the cyclooxygenase inhibitor, ibupro

237 ta in PIC-induced effects was studied by the coadministration of the cytokine antibodies with PIC, an

238 ist SKF81297 induced pMeCP2 widely; however, coadministration of the D(2)-class agonist quinpirole re

239 herapies in Tk2(-/-) mice: (1) dT+dC and (2) coadministration of the deaminase inhibitor, tetrahydrou

240 Coadministration of the extracellular protein OVA and th

241 The amnestic effect of AM251 was rescued by coadministration of the GABAA receptor antagonist bicucu

242 Severe bradycardia/bradyarrhythmia following coadministration of the HCV-NS5B prodrug sofosbuvir with

243 Strikingly, coadministration of the HDAC inhibitor sodium butyrate w

244 The effect of DMOG was abolished by coadministration of the HIF-1 inhibitor digoxin or by pr

245 As a pharmacological parallel, coadministration of the high-affinity D2 agonist, aripip

246 These effects were counteracted by coadministration of the mitochondrial complex I inhibito

247 Importantly, coadministration of the mTOR inhibitor rapamycin reduced

248 dation process was efficiently suppressed by coadministration of the N-WASP inhibitor wiskostatin.

249 icity and antitumor potency were enhanced by coadministration of the natural killer T-cell ligand 7DW

250 ty in vitro but not by the same magnitude as coadministration of the peptide and these antibiotics.

251 ddle-aged mice and was partially reversed by coadministration of the proinflammatory cytokine IL-12.

252 Y-maze model, an effect fully reversible by coadministration of the selective 5-HT(2C) antagonist SB

253 Coadministration of the serotonin 5-HT2A/2C antagonist m

254 Coadministration of the thrombin inhibitor hirudin or th

255 Intraplantar coadministration of the TRPA1 receptor antagonist AP-18

256 Interestingly, coadministration of the two agents acutely increased the

257 1D11 was equivalent or superior to losartan; coadministration of the two agents was not superior to 1

258 Coadministration of these agents (CAd-VECPDL1) exhibited

259 he period of protection against disease, but coadministration of this dose should not interfere with

260 alone also decreased islet inflammation, and coadministration of this reagent and a suboptimal dose o

261 In vivo, coadministration of tPA improved the anticancer efficacy

262 vide a better understanding of the effect of coadministration of transporter modulators on anticancer

263 xenograft model insensitive to trastuzumab, coadministration of trastuzumab with a fixed dose of T-D

264 The coadministration of TVR and unboosted ATV results in inc

265 rance, and to provide better compliance than coadministration of two drugs.

266 Coadministration of UPI peptide with cytotoxic chemother

267 d PBMCs from the same patient, we found that coadministration of urelumab and nivolumab was sufficien

268 Coadministration of Vi with anti-CD3 Ab reduces secretio

269 Coadministration of vorinostat dramatically increased MK

270 f cells with 4N or more DNA content, whereas coadministration of vorinostat markedly enhanced aurora

271 Stereotaxic coadministration of VU0360172 and ACEA into the infralim

272 Coadministration of wortmannin following trauma-hemorrha

273 Coadministration of Y2 receptor agonists and GLP-1 recep

274 evirapine-based antiretroviral therapy (ART) coadministration on levonorgestrel pharmacokinetics.

275 ence study assessed the effect of telaprevir coadministration on the pharmacokinetics of a single dos

276 In terms of antitumor efficacy, iRGD coadministration significantly augmented the individual

277 utaneous xenograft model, BEZ235 and ABT-737 coadministration significantly diminished tumor growth,

278 mor-bearing rats, with or without amifostine coadministration, via several routes.

279 mall decreases in AUC0-12 and C12 during RIF coadministration, warranting further evaluation in patie

280 EFV and RIF-based tuberculosis therapy coadministration was associated with a trend toward high

281 mulation; this effect was abrogated by HDACI coadministration, which suggests that cells undergoing D

282 temozolomide only delayed tumor growth, its coadministration with 5-NIdR caused complete tumor regre

283 ckade produced only modest benefit; however, coadministration with a 4-1BB agonist antibody promoted

284 moted antigen-specific immune responses upon coadministration with an antigen.

285 Coadministration with boceprevir decreased RTV AUC durin

286 ne derivatives 4b and 4d may be suitable for coadministration with chloroquine against chloroquine-re

287 ed that the hypertension may be prevented by coadministration with endostatin (ES), an endogenous ang

288 cer (CRPC), is often effective, but requires coadministration with glucocorticoids to curtail side ef

289 ed heat hyperalgesia that was potentiated by coadministration with IL-6.

290 ecific IgG after intramuscular or intranasal coadministration with inactivated H1N1 2009 pandemic vac

291 We found that coadministration with iRGD peptide did not have an impac

292 ubcutaneously as: (1) monotherapy, (2) acute coadministration with levodopa, and (3) chronic coadmini

293 ve, MSU-mediated antitumor activity required coadministration with Mycobacterium smegmatis to induce

294 In the validation study, coadministration with oral beta-glucuronidase derived fr

295 olled trials with lapaquistat monotherapy or coadministration with other lipid-altering drugs in dysl

296 Moreover, upon coadministration with rosiglitazone, T2384 was able to a

297 d exposure of both drugs compared with their coadministration with RTV.

298 Coadministration with steady-state telaprevir increased

299 The intravenous use of voriconazole requires coadministration with sulphobutylether-beta-cyclodextrin

300 Coadministration with telaprevir increased the terminal