ライフサイエンスコーパス: coarse

1 -deciduous spring phenology submodel at both coarse (0.9 x 1.25 degrees ) and fine (1 km) scales.

2 s in the accumulation (0.2-1.0 mum, 11%) and coarse (1.0-10.0 mum, 35%) modes.

3 o be mainly attributed to PAE stores in soil coarse (250-2000 mum) and fine sand (53-250 mum) fractio

4 as well as by small sample sizes, providing coarse and equivocal information about which brain areas

5 tails, natural vision can be decomposed into coarse and fine components.

6 trait painting can come from a collection of coarse and fine details, natural vision can be decompose

7 se same visual areas can be sensitive to how coarse and fine features line up in space.

8 unds were differentially distributed in seed coarse and fine fractions after dry fractionation proces

9 PAHs to predict health risks associated with coarse and fine PM.

10 simultaneously drive the response of total, coarse and fine root biomass to eCO2.

11 fractions with higher bioavailability (i.e., coarse and fine sands) showed greater influence on PAE c

12 ivities of bulk anise oil and its emulsions (coarse and nano) was tested by the minimum inhibitory co

13 the study of cognitive functions may appear coarse and old fashioned in its conventional uses.

14 This can be explained by the fact that coarse and PE bran hold more weakly bound water than gro

15 ional, more mobile water peak was noticed in coarse and PE bran, but not in ground bran.

16 O2 is expected to alter the biomass of fine, coarse and total roots to meet increased demand for othe

17 and a boat basin to mimic natural sediment (coarse) and anthropogenic (fine) sediment (common in dre

18 h the scale of the feature (fine, medium, or coarse) and the alignment of these features in space.

19 All such methods are limited to coarse approximations of only a few cell subpopulations,

20 icroscopy structure of TRPV1 only provides a coarse characterization of the location of capsaicin (CA

21 nt global climate regimes and identify where coarse climate data is most and least likely to reduce t

22 s that were analyzed histopathologically had coarse collagen fibers and 24 of 26 stained with Miller

23 n-related activity in V2 for a related task, coarse disparity discrimination, thought to rely on abso

24 A coarse emulsion containing beetroot juice as inner water

25 robial analyses indicated that both nano and coarse emulsions of anise oil showed better and long-ter

26 luding multiple older children who developed coarse features similar to those of storage disorders.

27 led to be informative, yet also sufficiently coarse for sampling to be exhaustive.

28 The seed coarse fraction significantly reduced NO and IL-6 produc

29 city with banana flours, especially with the coarse fraction.

30 nd flavonol derivatives were mainly found in coarse fraction.

31 racterized all nitrate parameters, except at coarse frequencies for nitrate flux.

32 However, within this coarse functional organization, we discovered that senso

33 The coarse geometric features of helical filaments are known

34 This approach uses the Martini coarse grain (CG) model to describe the receptors, lipid

35 coupled to yellow and consistent crumb, with coarse grain and well-perceivable sour taste and odor.

36 Coarse-grain (CG) molecular dynamics simulations are emp

37 Here, we have extended the coarse-grain Martini force field to include RNA after ou

38 To this end, we performed coarse-grain MD simulations of the Photosystem II comple

39 Experimental and coarse-grain modeling results reveal that systematic Mn

40 uantum mechanics and larger length scales of coarse-grain models.

41 mines its overall stiffness, we introduced a coarse-grain molecular dynamics model of the axon membra

42 Coarse-grain molecular dynamics simulations are a key to

43 We performed comparative atomistic and coarse-grain molecular-dynamics simulations of the LEL i

44 linked to the equilibrium statistics of the coarse-grain variables.

45 (48 J/cm(2)) is almost comparable to that of coarse grained (CG) Cu: 55 J/cm(2).

46 We use coarse grained protein conformational search, efficient

47 th different force-fields (both all-atom and coarse grained representations).

48 the dynamics, and both RNAs and proteins are coarse grained.

49 In this work, a combination of coarse-grained "Martini" and all-atom simulations are us

50 can be fine-grained (individual proteins) or coarse-grained (functionally-related protein groups) as

51 A coarse-grained alumina could also reach a translucency l

52 nal approaches-statistical mechanical model, coarse-grained and all-atom MD simulations-reveal that t

53 In both coarse-grained and all-atom molecular dynamics simulatio

54 combine molecular simulations based on both coarse-grained and atomistic models with coevolutionary

55 rate single-molecule force measurements with coarse-grained and atomistic simulations to resolve the

56 and electrical properties compared to their coarse-grained and nanograined counterparts.

57 time-dependent multidimensional data with a coarse-grained approach and map key dynamical features w

58 eld that are now underway, our physics-based coarse-grained approach to protein-structure prediction

59 Here, we use a multistage atomistic-coarse-grained approach, complemented by circular dichro

60 complementary roles that both atomistic and coarse-grained approaches play in such simulations.

61 protocol for mapping amino-acid sequences to coarse-grained beads enables the direct simulation of tr

62 The framework consists of a coarse-grained but mechanistic description of host physi

63 Here, we use coarse-grained computer simulations and the theory of as

64 vice for ab initio loop modeling combining a coarse-grained conformational search with a full-atom re

65 rs of magnitude higher than those in typical coarse-grained copper.

66 mics simulations with combined atomistic and coarse-grained description of NPs reveal the emergence o

67 er demonstrates the capability of the "quasi-coarse-grained dynamics" (QCGD) simulation method to unr

68 Results presented here utilize coarse-grained elastic network modeling to extract the d

69 For this purpose, we utilize coarse-grained elastic network models.

70 Using a coarse-grained energy landscape model, we predict the st

71 greater room-temperature strength than their coarse-grained equivalents, in part owing to a large red

72 We apply all-atom molecular dynamics and coarse-grained finite element modeling to DX-based nanop

73 mulate model lipid bilayers with the MARTINI coarse-grained force field on length scales of tens of n

74 dress this need, we propose a novel reactive coarse-grained force field, as well as a publicly availa

75 e dedicated equipment or limit themselves to coarse-grained force measurements on the micron scale.

76 n-specific signatures could be mapped to our coarse-grained framework to study self-assembly behavior

77 ural interpolation for the construction of a coarse-grained free energy landscape.

78 ph sampling protocol to construct and sample coarse-grained graph representations of RNAs from a give

79 fiber model, which couples fine-grained and coarse-grained HbS fiber models through a mesoscopic ada

80 We employed coarse-grained Langevin dynamics simulations to monitor

81 Here, we show that a coarse-grained lattice model like that of Chandler, when

82 ures of the clustered particle filtering are coarse-grained localization through the clustering of th

83 SpringSaLaD models biomolecules in a coarse-grained manner as a group of linked spherical sit

84 Here we construct and analyze a coarse-grained mathematical model of the fission yeast r

85 Coarse-grained MD reveals that the lipids reorganize loc

86 Using a combination of all-atom and coarse-grained MD simulations and sequence covariation a

87 to deal with a complex system is to build a coarse-grained model capable of catching its main physic

88 Here, we have used a coarse-grained model describing the relation between obs

89 Molecular dynamics simulations using a coarse-grained model enables estimation of free-energy l

90 We use an accurate coarse-grained model for DNA and stochastic molecular dy

91 ic generalization of a previously introduced coarse-grained model for stabilization of proteins by su

92 Using a unique coarse-grained model for the power stroke of a single MV

93 nd Molecular Dynamics simulations to study a coarse-grained model of cement formation, and investigat

94 Using a coarse-grained model of DNA and lac repressor (LacI) in

95 In this article, a coarse-grained model of pilus extension and attachment i

96 Here, we present a simple two-dimensional coarse-grained model of protein domain swapping in the c

97 xperiments, we performed simulations using a coarse-grained model of RNA to describe the response of

98 e perform Langevin dynamics simulations of a coarse-grained model of the ClpY ATPase-SP system to elu

99 A computationally efficient coarse-grained model of the erythrocyte membrane reveals

100 We use molecular simulations by creating a coarse-grained model of the MT-kinesin complex, which re

101 roximately 8 degrees ) using a residue-level coarse-grained model of the ribosome.

102 Here, we introduce a coarse-grained model that enables simulation of networks

103 timescales of fusion, we developed a highly coarse-grained model that retains key biophysical SNARE

104 We present a new coarse-grained model to realistically simulate the bindi

105 We use a coarse-grained model to represent proteins with varying

106 The coarse-grained model we consider is that of Ginzburg-Lan

107 We use our coarse-grained model with a set of secondary structural

108 rded as the simplest and most representative coarse-grained model, has been widely adopted to analyze

109 We have applied a structure-based coarse-grained model, with an explicit Debye-Huckel char

110 sely matching the level of resolution of the coarse-grained model.

111 attering with X-rays and neutrons coupled to coarse-grained modeling reveal that the intrinsically di

112 We performed systematic coarse-grained modeling using an elastic network model a

113 ons of these assemblies include all-atom and coarse-grained modeling, but modeling their conformation

114 Here we show atomistic, coarse-grained modelling combined with advanced simulati

115 Here the authors show atomistic and coarse-grained modelling combined with enhanced sampling

116 affinity of calcium (Ca(2+)) by integrating coarse-grained models and all-atomistic simulations with

117 folded proteins using atomistic simulations, coarse-grained models and analytic theory.

118 Coarse-grained models are compared with 3D cryo-electron

119 hesis, and most conventional structure-based coarse-grained models do not allow for nonnative structu

120 In this review we provide an overview of coarse-grained models focusing on their design, includin

121 e explore how APs achieve this by developing coarse-grained models for clathrin and AP2, employing a

122 n length for a spherical droplet; the use of coarse-grained models in the calculation of the interfac

123 Inevitably, such coarse-grained models introduce a set of phenomenologica

124 dy and analysis, construction of atomic from coarse-grained models is required.

125 Coarse-grained models represent attractive approaches to

126 led description is given for applications of coarse-grained models suitable for efficient combination

127 edure is general and can be adapted to other coarse-grained models.

128 ar magnetic resonance (NMR) spectroscopy and coarse-grained molecular dynamics (MD) simulations, we f

129 dvanced computational approach that combines Coarse-Grained molecular dynamics and well-tempered Meta

130 By using a multiscale coarse-grained molecular dynamics approach, we show that

131 We present OpenRBC, a coarse-grained molecular dynamics code, which is capable

132 t a nanopore snapshot approach combined with coarse-grained molecular dynamics simulation and master

133 We test this framework using coarse-grained molecular dynamics simulations and find i

134 experimental studies are also supported with coarse-grained molecular dynamics simulations and molecu

135 Coarse-grained molecular dynamics simulations are applie

136 mammalian cell membranes, we have performed coarse-grained molecular dynamics simulations containing

137 Consistent with this possibility, extensive coarse-grained molecular dynamics simulations of a BR tr

138 tor oligomerization we carried out extensive coarse-grained molecular dynamics simulations of crystal

139 We present coarse-grained molecular dynamics simulations of the eps

140 Coarse-grained molecular dynamics simulations of the str

141 Coarse-grained molecular dynamics simulations reveal a n

142 We do this using coarse-grained molecular dynamics simulations specifical

143 Here, we use high-throughput coarse-grained molecular dynamics simulations to charact

144 t into these systems, the present study used coarse-grained molecular dynamics simulations to describ

145 Here, we use atomistic and coarse-grained molecular dynamics simulations to investi

146 A combination of coarse-grained molecular dynamics simulations, Laurdan m

147 terized from nearly 200 mus of residue-based coarse-grained molecular dynamics simulations.

148 dent site-specific (1)H-(15)N HSQC data with coarse-grained molecular dynamics simulations.

149 lar structure of a BAR-domain scaffold using coarse-grained molecular dynamics simulations.

150 In this work, using coarse-grained molecular dynamics, the transmembrane dom

151 hate (PIP2) -containing lipid bilayer, using coarse-grained molecular dynamics.

152 on, we develop a particle model-resembling a coarse-grained molecular model-constructed to match the

153 Coarse-grained molecular simulations, which mimic glass

154 Coarse-grained Monte-Carlo simulations of the system are

155 -screw (TLS), liquid-like motions (LLM), and coarse-grained normal-modes (NM) models of protein motio

156 l of protein representation from all-atom to coarse-grained opens up new possibilities for studying p

157 Molecular dynamics simulations with coarse-grained or simplified Hamiltonians have proven to

158 a Voronoi partitioning of the point cloud of coarse-grained particles, and is continuously updated ov

159 These responses can be interpreted using a coarse-grained physical description of the cortex in ter

160 present the proposed formalism to construct coarse-grained potential models for three examples: an i

161 Using molecular dynamics simulations of coarse-grained predictive energy landscape models for th

162 etric binding energies for each state of the coarse-grained protein corresponding to the symmetry of

163 bly of single nucleosomes using a predictive coarse-grained protein DNA model with transferable force

164 A predictive coarse-grained protein force field [associative memory,

165 Using a predictive coarse-grained protein force field, we compute and compa

166 ng whether MS-based footprinting can provide coarse-grained protein structure by following structural

167 approach, expanding the recently established coarse-grained proteome allocation models from steady-st

168 evaluate the ability of the 3SPN.2 model, a coarse-grained representation designed to mimic B-DNA, t

169 es of molecular dynamics (MD) simulations at coarse-grained resolution for both the wild-type (WT) an

170 ures, we have developed an open software for coarse-grained RNA folding simulations, guided by human

171 We introduce a coarse-grained RNA model for molecular dynamics simulati

172 We develop a coarse-grained simulation approach for predicting equili

173 e integration efficiencies, obtained using a coarse-grained simulation approach, robustly predicted e

174 Unlike most coarse-grained simulation approaches, the higher-level o

175 ationally demanding than fully atomistic and coarse-grained simulation methodologies; however, it has

176 We present a coarse-grained simulation model that is capable of simul

177 Using a coarse-grained simulation model, we can reproduce the kn

178 Using a coarse-grained simulation model, we rationalized that th

179 We use a coarse-grained simulation that takes into account the di

180 -molecule force-spectroscopy experiments and coarse-grained simulation.

181 mbine atomistic molecular dynamics (MD) with coarse-grained simulations and statistical mechanical ca

182 A folding, and demonstrates the potential of coarse-grained simulations as a tool for rationally tuni

183 lecular modeling using atomic resolution and coarse-grained simulations corroborates our experimental

184 and instead support a model put forward from coarse-grained simulations indicating that binding is me

185 Coarse-grained simulations of a wide range of junction t

186 certainty by demonstrating the capability of coarse-grained simulations of membrane protein insertion

187 Using coarse-grained simulations of peptide self-assembly, we

188 The coarse-grained simulations quantitatively reproduce the

189 Combining theory and coarse-grained simulations shows that the DNA sequence a

190 ational strategy that combined atomistic and coarse-grained simulations with coevolutionary analysis

191 junction structure evaluated by all-atom and coarse-grained simulations.

192 we fused site-specific NMR information with coarse-grained simulations.

193 We carried out coarse-grained spatial stochastic binding simulations fo

194 Our coarse-grained structural model thus suggests that the h

195 In this study, we use a well-established coarse-grained three-dimensional model of DNA and seven

196 Gdansk group, we have used our physics-based coarse-grained UNited RESidue (UNRES) force field to pre

197 ved membranes; and 2) the self-assembly of a coarse-grained virus capsid protein model.

198 r molecular dynamics simulations, RACER (RnA CoarsE-gRained).

199 improved radiation tolerance comparing with coarse-grained, fully dense Au.

200 tial vegetation climate envelope models (for coarse-grained, large-scale predictions).

201 More generally, the aim is the extraction of coarse-grained, macroscopic information from stochastic

202 le microstructural damage in single-crystal, coarse-grained, ultrafine-grained and nanograined metals

203 Because of its large size, coarse graining helps to simplify and to aid in the unde

204 lly combining the Morone-Makse algorithm and coarse graining of the network in which we regard a comm

205 to improve model elaboration, refinement and coarse graining procedures to better understand the rele

206 in difficulties by applying a gradient-based coarse graining to RNA-ligand systems and solving the pr

207 In this study, we used a combination of coarse graining, hierarchical natural move Monte Carlo a

208 based multiscale simulations where a dynamic coarse-graining and force-blending method is required.

209 Efficient coarse-graining methods are required to reduce the intra

210 So far, exact and heuristic coarse-graining methods have been mostly restricted to t

211 r beds typically have an "armoured" layer of coarse grains on the surface, which acts to protect fine

212 he largest sediment loads on the planet, yet coarse gravel in these rivers vanishes within approximat

213 Caffeine concentrations in cold brew coarse grind samples were substantially higher than thei

214 ind, medium roast/medium grind, medium roast/coarse grind) using cold and hot methods.

215 samples (dark roast/medium grind, dark roast/coarse grind, medium roast/medium grind, medium roast/co

216 , precision grip with two or five digits, or coarse grip with five digits) and used representational

217 lecular mobility of water and biopolymers in coarse, ground, and pericarp-enriched (PE) wheat bran an

218 Coarse, ground, and pericarp-enriched bran were incorpor

219 level, although the chemical composition of coarse/ground bran and PE bran differed.

220 rganic P concentrations in fine (<1 mum) and coarse (>1 mum) aerosol fractions and used this data to

221 via a rapid subcortical route that conveys "coarse" information, namely, low spatial frequencies.

222 Langevin dynamics (LD) simulations on a very coarse landscape with a single rate-limiting barrier and

223 chniques that were labor-intensive, provided coarse levels of resolution, or were limited to populati

224 At coarse levels of taxonomic aggregation, phytoplankton an

225 Three different particle sizes (2<coarse<3.5, 1.6<medium<3.0, 0.5<fine<2.0 mm) of bulgur,

226 Coarse mode atmospheric aerosol particles are abundant i

227 Chloride exhibited a dominant coarse mode due to sea salt influence, with substantiall

228 ere highest at the road-side site and in the coarse mode, resulting in a fine mode pH < 2 and near ne

229 lting in a fine mode pH < 2 and near neutral coarse mode.

230 When sampling coarse-mode aerosol, mass changes of <10 pg can be detec

231 for sampling and detecting accumulation- and coarse-mode aerosol.

232 tions from fine-mode organic components plus coarse-mode transition metal ions.

233 e 23% and 51%, and 37% and 39%, for fine and coarse modes at the roadside and urban sites, respective

234 uble OP(DTT) was bimodal, with both fine and coarse modes.

235 nd supplied almost as much information about coarse natural image features as firing rates.

236 quality during storage was less affected for coarse or ground bran-rich bread compared to wheat flour

237 root biomass to eCO2, and that fine (but not coarse or total) root responses to eCO2 are positively r

238 ls (PBOA) represent a major component of the coarse organic matter (OMCOARSE, aerodynamic diameter >

239 We show that mice can transfer learning of a coarse orientation discrimination task involving first-o

240 Fish reared in coarse, oxic sites accumulate more elements with higher

241 deposition was mainly from accumulation and coarse particles.

242 eciduous woodland had the greatest stocks of coarse particulate matter (CPOM) and greater numbers of

243 Coarse particulate matter (P10-2.5) is primarily mechani

244 se; however, the association between ambient coarse particulate matter (PM10; </=10 mum in aerodynami

245 In London, samples of coarse PM collected on the top of a building over 18 mon

246 n children or adults were exposed to fine or coarse PM in different seasons.

247 latively higher than the risk of exposure to coarse PM in pathway activation.

248 d inorganic ions in nascent fine (PM2.5) and coarse (PM10-2.5) SSA and the sea surface microlayer (SS

249 nstrate that these resolutions are often too coarse relative to biologically relevant scales.

250 The coarse resolution AOGCMs outputs were statistically down

251 They are often also central to downscaling coarse resolution climate simulations from General Circu

252 nanophotonics has so far been limited by the coarse resolution of conventional inkjet-printing method

253 such conversion is uncertain because of the coarse resolution of satellite images and use of differe

254 anticyclones cannot be reliably estimated by coarse-resolution or even mesoscale-resolving models, wi

255 Alternately, coarse-resolution velocity metrics can be combined with

256 ologists study patterns at large extents and coarse resolutions, while community ecologists focus on

257 P50] reached at -1.8 MPa) and then in older, coarse roots (P50 = -3.5 MPa).

258 15) N redistributed from fine and especially coarse roots into cumulative litterfall and small accumu

259 ing five different setups combining fine and coarse sands or a mixture of both mimicking potential wa

260 a scale of tens of meters) rather than at a coarse scale (around several kilometers).

261 ural activity of each individual neuron from coarse scale data that has been spatially decimated by a

262 such a memory is reflected in cell size at a coarse scale.

263 By providing a coarse-scale evaluation of sustainable water use from sa

264 t, and it selectively reduces sensitivity to coarse-scale form signals.

265 h rainy summers have a stronger signature of coarse-scale processes.

266 s manipulation regulated the availability of coarse-scale relative disparity cues.

267 Coarse sediments showed higher biomass and activity in d

268 erceptual skill, revealing that the initial, coarse sensitivity to 3D information is refined, automat

269 nded with fine-sized (<0.2 mm) compared with coarse-sized (5.0 mm) fragments.

270 enough to be measurable with the relatively coarse Snellen test and that subjects with the poorest a

271 have either operated at the macroscale with coarse spatial and/or temporal resolution-e.g., magnetic

272 l and regional studies often analyze data at coarse spatial grains.

273 We suggest that climate data with a coarse spatial resolution is likely to reduce the accura

274 ion), and magnocellular responses contribute coarse spatial scale information when the visual system

275 The coarse spectral resolution afforded by the CI limits per

276 potentially contribute to the emergence of "coarse" speech representations in inferior frontal gyrus

277 icant fraction of organic matter in fine and coarse SSA (11 and 27%, respectively).

278 ched 14-1314-fold in fine SSA, 3-138-fold in coarse SSA, but only up to 1.0-16.2-fold in SSML.

279 n of the mesocosm, which was not observed in coarse SSA, sea-surface microlayer or in fresh seawater.

280 small individuals and strong preference for coarse substrates indicating higher pyrethroid sensitivi

281 ace area-weight ratio and the preference for coarse substrates significantly influenced the LC50 for

282 Increasingly coarse temporal features of speech spreading from poster

283 has, however, been limited by the typically coarse temporal resolution (monthly) of global climate m

284 t widely used neuroimaging method, fMRI, has coarse temporal resolution compared with the time-scale

285 Climate data with a coarse temporal resolution is likely to reduce the accur

286 act assessments also use climate data with a coarse temporal resolution.

287 Seven-up-initiated Imp/Syp gradients create coarse temporal windows within type II neuroblasts to pa

288 old subcortical pathway providing fast, but coarse, threat-related signals to human amygdala.

289 By overcoming the coarse time resolution of the array, our framework uniqu

290 liths and corresponds to the transition from coarse to deformed xenoliths.

291 We find that color selectivity evolves as a coarse to fine process from higher to lower levels withi

292 lution projections (~1 x 1 degrees ) are too coarse to inform conservation planning.

293 vasive neural stimulation techniques are too coarse to manipulate behaviors that correlate with fine-

294 On the other hand, sudden transition from coarse-to-fine grain sizes promoted a hot-spot of organi

295 inging on the retina in a way that initiates coarse-to-fine processing at each fixation.

296 ts and suggests that, rather than initiating coarse-to-fine processing, spatiotemporal coupling in th

297 tained with paralyzed eyes suggest that this coarse-to-fine sequence results from spatiotemporal filt

298 ets of aerosol optical depth (AOD) with only coarse (typically monthly) temporal resolution.

299 despite its simple formulation: A filter too coarse will allow suitably sized prey to pass unintercep

300 The death of oaks increased inputs of coarse woody debris to the surface of the soil, much of