ライフサイエンスコーパス: coated pit

1 s primarily or exclusively in a newly formed coated pit.

2 cond, with fission of the membrane neck of a coated pit.

3 llularly into EEA-1+ endosomes from clathrin-coated pits.

4 T-1-HA-GFP internalization requires clathrin-coated pits.

5 of bulky extracellular domains from clathrin-coated pits.

6 ons reduce recruitment efficiency of OCRL to coated pits.

7 ent redistribution of arrestin2L to clathrin-coated pits.

8 imilar to how clathrin attracts molecules to coated pits.

9 cles/tubules and exocytosis through clathrin-coated pits.

10 n, which binds to the endocytic machinery of coated pits.

11 helial cells but is internalized in clathrin-coated pits.

12 ecessary for its internalization by clathrin-coated pits.

13 in, the major structural protein of clathrin-coated pits.

14 been viewed as being initiated via clathrin-coated pits.

15 oteins are essential for fission of clathrin-coated pits.

16 er with transferrin receptor and to clathrin-coated pits.

17 ling molecules, and the presence of clathrin-coated pits.

18 nternalized rapidly, likely through clathrin-coated pits.

19 and are distinct from caveolae and clathrin-coated pits.

20 ARH-associated LDLR clustering into clathrin-coated pits.

21 sociation of adaptor protein-2 with clathrin-coated pits.

22 oughout the lifetime of the growing clathrin-coated pits.

23 own-regulates CD4 by linking CD4 to clathrin-coated pits.

24 ve that SNX9 partially localizes to clathrin-coated pits.

25 ht guide or insert the complex into clathrin-coated pits.

26 roximately 27-fold excess of LDLR outside of coated pits.

27 ins, including beta-arrestin-2 with clathrin-coated pits.

28 esses promote endocytosis of Smo in clathrin-coated pits.

29 in assembly of functionally active clathrin-coated pits.

30 PSMA undergoes internalization via clathrin-coated pits.

31 been implicated in the formation of clathrin-coated pits.

32 ugh spatial segregation of a GAP in clathrin-coated pits.

33 a clathrin/dephosphin-mediated retrieval via coated pits.

34 lls but are prevented from entering clathrin-coated pits.

35 Grb2 binding sites do not efficiently enter coated pits.

36 eps of EGFR internalization through clathrin-coated pits.

37 phosphorylation directs it through clathrin-coated pits.

38 nter non-raft membrane, from which it enters coated pits.

39 sting that endocytosis occurred via clathrin-coated pits.

40 desensitization and endocytosis via clathrin-coated pits.

41 mediating arrestin interaction with clathrin-coated pits.

42 n upon Wnt-induced recruitment into clathrin-coated pits.

43 he proteins for internalization via clathrin-coated pits.

44 alian cells, they are excluded from clathrin-coated pits.

45 clathrin adaptor protein 2 (AP2) at clathrin-coated pits.

46 table endocytic vesicles arise from clathrin-coated pits.

47 so found to enter the cell predominantly via coated pits.

48 mine the number of dynamins recruited to the coated pits.

49 VECs), increasing NP uptake through clathrin-coated pits.

50 to invagination and then fission of clathrin-coated pits.

51 is and is undetectable in endocytic clathrin-coated pits.

52 e protein (WASP) assembles actin at clathrin-coated pits.

53 mechanism for endocytosis involves clathrin-coated pits [1], but evidence has accumulated for additi

54 investigate the massive increase in clathrin-coated pit abundance that is selectively observed at a s

55 d to contribute to the formation of clathrin-coated pits, although the specific components that conne

56 d at the constricting neck of a fully formed coated pit and immediately after vesicle budding, accumu

57 GAK was disrupted showed a lack of clathrin-coated pits and a complete block in clathrin-mediated en

58 ults in an accumulation of arrested clathrin-coated pits and a greatly reduced synaptic vesicle numbe

59 n-mediated endocytosis with shallow clathrin-coated pits and a strong reduction in the internalizatio

60 interaction of DAT with adaptor proteins in coated pits and acceleration of DAT endocytosis.

61 th clathrin assembly into endocytic clathrin-coated pits and active Cdc42.

62 olocalizes with clathrin and AP2 in clathrin-coated pits and at the leading edge of migrating cells.

63 t OCRL visits late-stage, endocytic clathrin-coated pits and binds the Rab5 effector APPL1 on periphe

64 h receptor-mediated endocytosis via clathrin-coated pits and caveolae, that actin filaments and micro

65 , accompanied by an accumulation of clathrin-coated pits and caveolae.

66 hat is insensitive to inhibitors of clathrin-coated pits and caveolae.

67 e peptides inhibit the formation of clathrin-coated pits and coated vesicles during synaptic vesicle

68 or, which is highly concentrated at clathrin-coated pits and coordinates acquisition of bilayer curva

69 ution, we detected the arrival of dynamin at coated pits and defined dynamin dimers as the preferred

70 oblasts, these two receptors co-localized in coated pits and endosomal compartments following PDGF st

71 hway that involves the formation of clathrin-coated pits and fusion to early endosomes.

72 ich were concentrated at late-stage clathrin-coated pits and in lamellipodia, also dissociated from t

73 ARH colocalizes with megalin in clathrin coated pits and in recycling endosomes in the Golgi regi

74 NM23-H1/H2 localized at clathrin-coated pits and interacted with the proline-rich domain

75 te that E-selectin clusters in both clathrin-coated pits and lipid rafts of endothelial cells but is

76 Clathrin coated pits and numerous uncoated intracellular vesicles

77 t whether cortactin associates with clathrin-coated pits and participates in receptor-mediated endocy

78 distinct endocytic pathways (i.e., clathrin-coated pits and plasma membrane lipid rafts) that delive

79 7 is constitutively internalised by clathrin-coated pits and that physiological stimulators such as G

80 ution images of living cells, using clathrin-coated pits and the transferrin cargo as model systems.

81 rafficking; it is recruited to both clathrin-coated pits and to ensuing uncoated endocytic vesicles (

82 d FcRY-mediated internalization via clathrin-coated pits and transport involving early and recycling

83 The lattices of clathrin-coated pits and vesicles are comprised of triskelions, e

84 in, and F-actin and increased the amounts of coated pits and vesicles at the apical plasma membrane.

85 n, immunoelectron microscopy showed AP-1B in coated pits and vesicles at the plasma membrane during c

86 ent Sec5 is unexpectedly present in clathrin-coated pits and vesicles at the plasma membrane.

87 Clathrin assembly into coated pits and vesicles is promoted by accessory protei

88 in heavy chain (Chc), a major constituent of coated pits and vesicles, is the most abundant protein c

89 e cellular machineries, such as the clathrin-coated pits and vesicles.

90 in 2 depletion causes a decrease in clathrin-coated pits and vesicles.

91 selective increase in unconstricted clathrin-coated pits and, in the case of swinholide, an additiona

92 We propose that RME-4 functions on coated pits and/or vesicles to recruit RAB-35, which in

93 Ack is concentrated at clathrin-coated pits, and binds clathrin heavy chain via two clat

94 rotein required for the assembly of clathrin-coated pits, and DN PAK-1, an obligate mediator of macro

95 s from the plasma membrane, through clathrin-coated pits, and into the cell for lysosomal degradation

96 A associates with Arc, localizes to clathrin-coated pits, and is associated with endocytic sites in d

97 ents, three-dimensional tracking of clathrin-coated pits, and long-term imaging spanning >10 h and en

98 ternalization was also dependent on clathrin-coated pits, and Lp(a) was targeted for lysosomal and no

99 adhesions, primary cilia, caveolae, clathrin-coated pits, and plaques play additional key roles.

100 interacts with AP-2, is enriched on clathrin-coated pits, and requires clathrin but not RAB-5 for cor

101 to G proteins, internalization via clathrin-coated pits, and signaling via a growing list of "scaffo

102 tered into HRPTEC via caveolae, not clathrin-coated pits, and that BKV is maximally associated with c

103 re most likely internalized through clathrin-coated pits, and then returned to the plasma membrane vi

104 to be internalized independently of clathrin-coated pits, and there is evidence to suggest that lipid

105 reveal distinct mechanisms for sorting into coated pits, and thereby explain differential effects on

106 th clathrin and other components of clathrin-coated pits, AP-2 did not seem to be present in clathrin

107 Clathrin-coated pits are a major entry portal where assembled cla

108 r whether the cargos in the growing clathrin-coated pits are actively monitored by the coat assembly

109 We conclude that clathrin-coated pits are dynamic structures with rapid exchange o

110 rin in the cytosol, suggesting that clathrin-coated pits are dynamic structures.

111 naling, in cells in which endocytic clathrin-coated pits are frozen at a deeply invaginated state, th

112 Clathrin-coated pits are well defined, but the identity, mechanis

113 ciated endocytic adapters recruit cargoes to coated pits as a first step in endocytosis.

114 in multimolecular clusters unassociated with coated pits, as assessed by immuno-electron microscopy.

115 ucing GLUT1 internalization through clathrin-coated pits, as well as indirectly, by reducing the leve

116 Coated pits assemble by growth of a clathrin lattice, wh

117 Clathrin-coated pits assemble on a membrane and pinch off as coat

118 ilins in abortive pits or at any time during coated pit assembly.

119 ro cells is slow, is independent of clathrin-coated-pit assembly, is dependent on an intact caveolin-

120 Clathrin-coated pits associated with the plasma membrane were sti

121 y a dominant negative mutant of the clathrin-coated pit-associated protein Eps15.

122 ved during recruitment of EGF receptors into coated pits at 4 degrees C and reached maximum at 37 deg

123 EETI-II-positive macropinosomes and clathrin-coated pits at early time points after treatment of cell

124 ulation of clathrin, accessory proteins, and coated pits at the apical plasma membrane.

125 Despite the identification of clathrin-coated pits at the cell surface over 30 years ago, the f

126 ompound that induces misassembly of clathrin-coated pits at the cell surface.

127 mbles around the necks of deeply invaginated coated pits at the plasma membrane and catalyzes vesicle

128 he clathrin adaptors AP2 and AP1 in clathrin-coated pits at the plasma membrane and trans-Golgi netwo

129 etramers stimulates formation of constricted coated pits at the plasma membrane by regulating the cha

130 er photobleaching, that clathrin in clathrin-coated pits at the plasma membrane exchanges with free c

131 s with membranes, and the number of clathrin-coated pits at the plasma membrane increased when PIP2 i

132 the scission of deeply invaginated clathrin-coated pits at the plasma membrane, but the mechanisms g

133 dynamin, which severs the necks of clathrin-coated pits at the plasma membrane.

134 hat both BRAG2 and Arf5 localize to clathrin-coated pits at the plasma membrane.

135 lathrin-coated vesicles, but not of clathrin-coated pits, at synapses.

136 creases beyond the size of a single clathrin-coated pit, B cells retrieve receptor clusters using lar

137 of EPS15, an essential component of clathrin-coated pits, blocked the entry of RRV into RFs.

138 ficantly affecting the structure of clathrin-coated pits, both clathrin and AP2 at the plasma membran

139 The latter suggests that coated pits bud from these regions.

140 a-arrestin directs the receptors to clathrin-coated pits but does not internalize with them.

141 e HCl, which blocks endocytosis via clathrin-coated pits, but not by nystatin and cholera toxin B, wh

142 orming a collar around the necks of clathrin-coated pits, but the specific structural interactions an

143 errin receptor is incorporated into clathrin-coated pits by associating, via tyrosine-based motifs, w

144 ctivated receptors are recruited to clathrin-coated pits by beta-arrestins, scaffolding proteins that

145 marked as cargo for inclusion into clathrin-coated pits by common internalization signals (e.g. YXXP

146 earchers to observe the dynamics of clathrin-coated pit (CCP) assembly in real time.

147 n 2 (AP2) complexes, which initiate clathrin-coated pit (CCP) assembly, are activated by conformation

148 Live-cell imaging of individual clathrin-coated pit (CCP) dynamics has revealed a broad variation

149 Analysis of clathrin-coated pit (CCP) dynamics led us to propose the existenc

150 sitive and quantitative analysis of clathrin-coated pit (CCP) dynamics, we have evaluated the differe

151 hought to play an important role in clathrin-coated pit (CCP) dynamics.

152 arks the isolation of a cargo-laden clathrin-coated pit (CCP) from the cell exterior.

153 corresponded to a decreased rate of clathrin-coated pit (CCP) initiation and increased lifetimes of p

154 phosphorylation event starts during clathrin-coated pit (CCP) initiation and increases throughout CCP

155 ACT: Some endocytic cargoes control clathrin-coated pit (CCP) maturation, but it is not known how suc

156 t of cargo molecules into a growing clathrin-coated pit (CCP).

157 Clathrin-coated pits (CCPs) are generally considered a uniform po

158 l CME proceeds via the formation of clathrin-coated pits (CCPs) at the plasma membrane, which invagin

159 fect the morphology and kinetics of clathrin-coated pits (CCPs) by directly following their dynamics

160 Clathrin-coated pits (CCPs) in proximity to substrate contacts ex

161 mediate assembly and maturation of clathrin-coated pits (CCPs) into cargo-containing vesicles.

162 abortive coats (ACs) from bona fide clathrin-coated pits (CCPs) is required but unaccomplished.

163 Consistently, Lpd localizes to clathrin-coated pits (CCPs) just before vesicle scission and regu

164 observed heterogeneous dynamics of clathrin-coated pits (CCPs) might be the different cargo content.

165 tors, either recruiting cargos into clathrin-coated pits (CCPs) or initiating clathrin-coat assembly

166 bilization and growth/maturation of clathrin-coated pits (CCPs) that eventually pinch off and interna

167 ocytosis occurs via the assembly of clathrin-coated pits (CCPs) that invaginate and pinch off to form

168 fate by regulating the dynamics of clathrin-coated pits (CCPs) that mediate their internalization.

169 tures at the plasma membrane termed clathrin-coated pits (CCPs) that mediate vesicle formation.

170 ial increase in the ratio of "open" clathrin-coated pits (CCPs) to "necked"/"closed" CCVs and a doubl

171 on of the lifetime distributions of clathrin-coated pits (CCPs) to measure independent aspects of CCP

172 ls and is concentrated at endocytic clathrin-coated pits (CCPs) via interactions with the scaffold pr

173 ME is initiated by the formation of clathrin-coated pits (CCPs), in which adaptors nucleate clathrin

174 e known to accumulate into maturing clathrin-coated pits (CCPs), whether and how cargo recruitment af

175 nt of adaptors and clathrin to form clathrin-coated pits (CCPs).

176 on of clathrin-coated vesicles from clathrin-coated pits (CCPs).

177 teraction of BMPRs with proteins in clathrin-coated pits (CCPs).

178 regulated by their endocytosis via clathrin-coated pits (CCPs).

179 at markedly affect the structure of clathrin-coated pits, clathrin exchange was blocked but AP2 at th

180 eractor, is recruited to late-stage clathrin-coated pits, clinical manifestations have been primarily

181 akdown on the dynamics of endocytic clathrin-coated pit components and of the actin regulatory comple

182 Capsids that did not encounter a coated pit dissociated from the cell surface with a half

183 they are recruited to a diffraction-limited coated pit during its assembly at the plasma membrane.

184 ates initially in the maturation of clathrin-coated pits during early stages of synaptic vesicle recy

185 this paper, we describe a study of clathrin-coated pit dynamics in living cells using ion conductanc

186 increased rates of CME and altered clathrin-coated pit dynamics.

187 ent endocytosis of heptahelical receptors in coated pits employs the clathrin adaptor beta-arrestin p

188 density lipoprotein (LDL) receptor (LDLR) in coated pits employs the clathrin adaptor protein ARH.

189 s and its metabolic processing, the clathrin-coated pit endocytosis pathway, and the ubiquitin/26 S p

190 hout MYO7B or actin filaments, many clathrin-coated pits fail to be severed from the membrane, causin

191 , ARH and megalin are first seen in clathrin coated pits followed by sequential localization in early

192 ARH recruits ROMK to clathrin-coated pits for constitutive and WNK1-stimuated endocyto

193 sue culture-adapted strains utilize clathrin-coated pits for entry.

194 ional hot spots, from which large numbers of coated pits form and vesicles are generated.

195 uggest a role for synaptojanin 2 in clathrin-coated pit formation and imply that lipid hydrolysis is

196 efore function to initiate calcium-regulated coated pit formation at the cell surface or on intracell

197 nding domain of AP180, which blocks clathrin-coated pit formation but not clathrin-independent endocy

198 t for myosin VI in membrane invagination and coated pit formation in enterocytes.

199 imately 75 s, similar to the time scales for coated pit formation seen in cells.

200 clathrin-coated vesicle formation, including coated pit formation, constriction, and internalization.

201 Stationary coated pits formed and budded on the remainder of the do

202 of Nef and the component(s) of the clathrin-coated pits has not been pinpointed.

203 e motifs that mediate EGFR interactions with coated pits have not been mapped.

204 is low-pH dependent occurs through clathrin-coated pits in a manner similar to wild-type virus.

205 A subpopulation of clathrin-coated pits in cell bodies and dendrites label for GluR2

206 ally believed that the formation of clathrin-coated pits in epithelial cells occurs randomly along th

207 , MORs are rapidly internalized via clathrin-coated pits in heterologous cells and dissociated striat

208 of cargo sorting and endocytosis by clathrin-coated pits in living cells.

209 diated endocytosis, is recruited to clathrin-coated pits in two sequential phases.

210 remain defective in the scission of clathrin-coated pits in vivo.

211 The membrane of an assembling coated pit, in equilibrium with the surrounding plasma m

212 nt internalization, indicating that clathrin-coated pits, in concert with mechanisms dependent on raf

213 nvaginations accumulated, capped by clathrin-coated pits, in synapses of dynamin 1-knockout mice.

214 lly defined by the cytoskeleton and clathrin-coated pits, in which receptors and G proteins are confi

215 ccessory proteins typical of plasma membrane-coated pits, including AP2, AP180, and epsin, but not Hi

216 rafts, the actin cytoskeleton, and clathrin-coated pits influences B cell signaling and antigen pres

217 Our data lead to a model in which coated pits initiate randomly but collapse unless stabil

218 On U373 cells, coated pits initiated on the dorsal membrane at the fron

219 This objective picture of coated pit initiation also shows that methods outlined h

220 ce of molecular events required for clathrin-coated pit initiation.

221 Two types of coated pit intermediates accumulate during dynasore trea

222 uit and polymerize clathrin to form clathrin-coated pits into which cargo is sorted.

223 Clathrin-coated pits invaginate from specific membrane compartmen

224 on of the SNX9.dynamin-2 complex to clathrin-coated pits is blocked by interactions with the abundant

225 of G protein-coupled receptors via clathrin-coated pits is dependent on the adaptor protein beta-arr

226 mediated cholesterol uptake through clathrin-coated pits is now well understood, the molecular detail

227 3-kinase C2alpha at plasma membrane clathrin-coated pits is spatially segregated from its hydrolysis

228 hich to engage adaptors to recruit them into coated pits, is problematical; that of prion protein in

229 Coated pits, junctional complexes, desmosomes, and basem

230 olocalization of EGF-rhodamine conjugate and coated pits labeled with yellow-fluorescent-protein-tagg

231 15 is found at the growing edges of clathrin-coated pits, leading to the hypothesis that it participa

232 laterally diffused into assembling clathrin-coated pits less than 30 s after attachment.

233 microscopy, which revealed cadherin-enriched coated pit-like structures in close association with adh

234 and TGN46, but not the AP-2 plasma membrane-coated pit marker nor the endosomal markers EEA1, Hrs, a

235 of neutral sphingomyelinase but not clathrin-coated pit maturation.

236 The first is associated with coated pit maturation; the second, with fission of the m

237 ter that is a critical component of clathrin-coated pit-mediated endocytosis, as well as in stress re

238 h chase and became undetectable if clathrin-coated pit-mediated trafficking was blocked with chlorpr

239 om the circulatory and lymphatic systems via coated pit-mediated uptake.

240 and-bound EGFR is incorporated into clathrin-coated pits--membrane structures containing clathrin and

241 the receptors can exhibit mean lifetimes in coated pits much shorter than the lifetime of the pit at

242 Coated pits near synapses typically lack GluR2 label und

243 sensors, disappearance of endocytic clathrin-coated pits, nearly complete inhibition of KCNQ2/3 chann

244 vate the concentration of PtdIns(4,5)P(2) at coated pit necks, and effectively cluster (or sequester)

245 t a model in which endophilin recruitment to coated pit necks, because of its curvature-sensing prope

246 ns facilitate cargo recruitment and clathrin-coated pit nucleation.

247 ndocytosis through the formation of clathrin-coated pits on the cell membrane.

248 microscopy to study the assembly dynamics of coated pits on the dorsal and ventral membranes of migra

249 tors are delivered selectively from clathrin-coated pits on the plasma membrane into a specific subpo

250 complex accumulates at a subset of clathrin-coated pits on the surface of human cells.

251 l 3-kinase, and dynamin 2, although clathrin-coated pits or caveolae are not required.

252 No clathrin-coated pits or vesicles could be detected in the clathri

253 ming that uptake is mediated by the clathrin-coated pit pathway.

254 At clathrin-coated pits, PI(3)P is produced by the INPP4A hydrolysis

255 on, up to a final value of 30 nm just before coated-pit pinching and formation of the coated vesicle.

256 clathrin/AP-2 puncta may represent loci for coated pit production and that previous models that assu

257 A large fraction of budding coated pits recruit between 26 and 40 dynamins (between

258 ite may represent receptor interactions with coated-pit regions in the cell membrane or with other ce

259 to coordinate cargo selection into clathrin-coated pits, results in a significant impairment in endo

260 ansmembrane receptors requires that clathrin-coated pits retain the receptors long enough to allow ve

261 vity, and axonal boutons containing clathrin-coated pits showed a more pronounced decrease in presyna

262 t due to failure of receptors to localize in coated pits since the number of LDLRs in coated pits was

263 the recruitment of P-selectin into clathrin-coated pits, slowed the internalization of P-selectin, a

264 nd it remains controversial whether clathrin-coated pits specialize to internalize particular recepto

265 ment of adaptor proteins present in clathrin-coated pits, such as epsin, Eps15 (epidermal growth fact

266 enrichment of LDLR-Y807C-bound beta-VLDL in coated pits, suggesting that beta-VLDL binding promoted

267 QHF, and NPLY) provide redundancy to mediate coated pit targeting and endocytosis of HARE.

268 Dab2 colocalizes with integrin beta1 in coated pits that are dispersed over the cell surface, su

269 ted DSL proteins to a particular subclass of coated pits that have special properties essential for N

270 t burst of EGFP-SNX9 recruitment to clathrin-coated pits that occurs during the late stages of vesicl

271 ends on the formation of functional clathrin-coated pits that recruit cargos and mediate the uptake o

272 lin is required for constriction of clathrin-coated pits, the same early step in endocytosis known to

273 en as the cargoes being enclosed in clathrin-coated pits, they slow down the active rotation and expe

274 an adaptor that couples late-stage endocytic coated pits to actin polymerization and which we found t

275 eveal a link between progression of clathrin-coated pits to endocytic vesicles and an activation-deac

276 nd hence in oocytes is recruited to clathrin-coated pits to facilitate the rapid recycling of Yolkles

277 indings indicate that BRAG2 acts at clathrin-coated pits to promote integrin internalization by activ

278 bsence of SCAR, some WASP relocated from the coated pits to the leading edge, where it behaved with s

279 5 that is an essential component of clathrin-coated pits, to investigate the extent and importance of

280 is of ligand-receptor complexes via clathrin-coated pits, trafficking of the internalized ligand to l

281 s via endocytic components, such as clathrin-coated pits, vacuoles, and micropinocytic vesicles.

282 ted endocytosis and associates with clathrin-coated pits/vesicles at the plasma membrane.

283 cells, LKT moves to lipid rafts and clathrin-coated pits via a dynamic process that results in LKT in

284 olution imaging of microtubules and clathrin-coated pits was demonstrated, under both modes.

285 in coated pits since the number of LDLRs in coated pits was similar in ARH-/- and normal cells.

286 INPP5B visits late stage endocytic clathrin-coated pits, was earlier shown to contain another bindin

287 ivated PAR1 internalization through clathrin-coated pits we examined the function of a highly conserv

288 s they were swept back toward the cell body; coated pits were absent from the corresponding ventral m

289 did not show any sign of a protein coat, and coated pits were not detected.

290 h encodes a protein associated with clathrin-coated pits where cell-surface receptors reside.

291 e sorting nexin, SNX9, localizes to clathrin-coated pits where it interacts with dynamin and function

292 ism for 7TMR internalization is via clathrin-coated pits, where clathrin and adaptor protein complex

293 omplex with the GTPase dynamin-2 at clathrin-coated pits, where it provokes fission of vesicles to co

294 e at the base of arrested endocytic clathrin-coated pits, where they support the growth of dynamic lo

295 nternalized, P-selectin clusters in clathrin-coated pits, which enhances its ability to support leuko

296 esicles and an increase in U-shaped clathrin-coated pits, which may result from sequestration of coat

297 When and where a clathrin-coated pit will form and what cargo it will contain are

298 domain of E-selectin or disrupting clathrin-coated pits with hypertonic medium blocked internalizati

299 and is thought to coordinate constriction of coated pits with membrane fission (via dynamin) and subs

300 defect included an accumulation of clathrin-coated pits with wide necks, as previously observed afte