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1 s) or by protein-protein interactions (e.g., coated vesicles).
2 (2)) to form the outer layer of the clathrin-coated vesicle.
3 peared together upon formation of a clathrin-coated vesicle.
4 ore coated-pit pinching and formation of the coated vesicle.
5 pression inhibited the uncoating of clathrin-coated vesicles.
6 ermore, PC7 was present in isolated clathrin-coated vesicles.
7 (+) channel that is internalized by clathrin-coated vesicles.
8 a morphology distinct from that of clathrin-coated vesicles.
9 c70-dependent clathrin uncoating of clathrin-coated vesicles.
10 he ability to inhibit the formation of CopII coated vesicles.
11 jected terminals, without affecting clathrin-coated vesicles.
12 reduction in the internalization of clathrin-coated vesicles.
13 and HCs encoded by chc1-box formed clathrin-coated vesicles.
14 at proteins that drive formation of clathrin-coated vesicles.
15 early secretory pathway is mediated by COPII-coated vesicles.
16 icle scission and also in uncoating Clathrin-coated vesicles.
17 which triggers the formation of new clathrin-coated vesicles.
18 e range of cargo accommodated by human COPII-coated vesicles.
19 nd beta-arrestin 1 (beta-Arr1) into clathrin-coated vesicles.
20 range of cargo proteins packaged into COPII-coated vesicles.
21 al of a postfusion SNARE complex in clathrin-coated vesicles.
22 which comprises the coat framework of COPII-coated vesicles.
23 80, also regulates the formation of clathrin-coated vesicles.
24 rted from the endoplasmic reticulum by COPII coated vesicles.
25 ning cargoes for incorporation into clathrin-coated vesicles.
26 Grb2/Sos1 complexes associated with clathrin-coated vesicles.
27 pits assemble on a membrane and pinch off as coated vesicles.
28 receptors into distinct cohorts of clathrin-coated vesicles.
29 gh its secretory pathway is dependent on GGA-coated vesicles.
30 localization of unsheathed mum with clathrin-coated vesicles.
31 sorting of an ER membrane protein into COPII-coated vesicles.
32 diators of cargo protein sorting in clathrin-coated vesicles.
33 rom the membrane and sequestered in clathrin-coated vesicles.
34 lization of the LDL receptor within clathrin-coated vesicles.
35 cific membrane compartments and pinch off as coated vesicles.
36 ant component of the LC, interacts with COPI-coated vesicles.
37 nt with this, WIPI49 is enriched in clathrin-coated vesicles.
38 Scap to bind COPII proteins for transport in coated vesicles.
39 ot Galpha(q), internalized with the clathrin-coated vesicles.
40 ct from those of well-characterized clathrin-coated vesicles.
41 teins that promote the formation of clathrin-coated vesicles.
42 membrane vesicles, microsomes, and clathrin-coated vesicles.
43 ocytosis and membrane recycling via clathrin-coated vesicles.
44 tein which is involved in uncoating clathrin-coated vesicles.
45 ransport of proteins in COPII (coat protein)-coated vesicles.
46 h CCPs, and DOR is internalized via clathrin-coated vesicles.
47 sis that it participates in the formation of coated vesicles.
48 uptake occurs in both caveolae- and clathrin-coated vesicles.
49 adaptor in mediating SAC1 transport in COPII-coated vesicles.
50 o proteins and promotes assembly of clathrin-coated vesicles.
51 teins' role in the struggle to make clathrin-coated vesicles.
52 ly, in the fission and uncoating of clathrin-coated vesicles.
53 ing its transport in coat protein complex II-coated vesicles.
54 n events, including the scission of clathrin-coated vesicles.
55 C7 requires endocytosis into acidic clathrin-coated vesicles.
56 membrane to begin the formation of clathrin-coated vesicles.
57 0, thus initiating uncoating of the clathrin-coated vesicles.
58 bind cargo and grow in size to form clathrin-coated vesicles.
59 ternalization of PC7 is mediated by clathrin-coated vesicles.
60 endocytosis and is associated with clathrin-coated vesicles.
61 key roles in transport mediated by clathrin-coated vesicles.
64 tion of Golgi-derived coat protomer I (COPI)-coated vesicles after activating or inhibiting signaling
65 l receptor (TCR) internalization by clathrin-coated vesicles after encounter with antigen has been im
66 se cells exhibit an accumulation of clathrin-coated vesicles and an increase in U-shaped clathrin-coa
67 TRAPPII is enriched on COPI (Coat Protein I)-coated vesicles and buds, but not Golgi cisternae, and i
69 hat is required for localization to clathrin-coated vesicles and contains a putative pleckstrin-homol
70 ficient mice display an increase in clathrin-coated vesicles and delayed reentry of recycling vesicle
71 ion, including accumulation of free clathrin-coated vesicles and delayed vesicle reavailability, impl
72 protein preparations extracted from clathrin-coated vesicles and directly binds to both clathrin and
75 at REEP6 is detected in a subset of Clathrin-coated vesicles and interacts with the t-SNARE, Syntaxin
76 ins, we showed that HCVpp enter via clathrin-coated vesicles and require delivery to early but not to
77 related JC virus can enter cells in clathrin-coated vesicles and subsequently traffic to caveolae, th
78 promoting its internalization into clathrin-coated vesicles and the consequent disassembly of interc
79 lattice organization of individual clathrin-coated vesicles and the disposition of the captured vesi
82 Moreover, similarities between structures in coated vesicles and those in the NPC support our prior h
83 -ER transport vesicles, different from COPII-coated vesicles and those involved in traffic of VSVG.
84 ound to be associated with isolated clathrin-coated vesicles and to colocalize with clathrin light ch
85 previously found to be enriched in clathrin-coated vesicles and to promote clathrin assembly in vitr
86 r c-Met is rapidly internalized via clathrin-coated vesicles and traffics through an early endosomal
87 pter complex of the "inner" coat in clathrin-coated vesicles, and a heterotrimeric B-subcomplex, whic
88 s from mammalian macrophages, also uses WASH-coated vesicles, and cells expressing dominant negative
89 ts including the nuclear pore complex, COPII-coated vesicles, and inside the nucleus as a transcripti
91 1 that are larger than conventional clathrin-coated vesicles, and that undergo long-range translocati
92 structures, including mitochondria, clathrin-coated vesicles, and the actin cytoskeleton, in either H
93 o ribosomal assembly, the formation of Golgi-coated vesicles, and the maintenance of PS asymmetry.
94 rmine the functional specificity of clathrin-coated vesicles, and together they control a multitude o
95 extends to less well characterized types of coated vesicles, and we identify and characterize the fi
97 mately 300-nm diameter) and typical clathrin-coated vesicles ( approximately 90 nm) makes it unlikely
98 evidence that, as in animal cells, clathrin-coated vesicles are a major means of internalisation by
113 tors required both for formation of clathrin-coated vesicles at the TGN (the Chc1p clathrin heavy cha
114 participates in cargo sorting into clathrin-coated vesicles at the trans-Golgi network (TGN) and end
118 putative identities and included a clathrin-coated vesicle ATPase, peroxisomal farnesylated protein,
121 tion that measures coat subunit assembly and coated vesicle budding on chemically defined synthetic l
124 er auxilin or GAK, not only uncoats clathrin-coated vesicles but also acts as a chaperone during clat
125 l of receptors from the membrane in clathrin-coated vesicles, but it remains unclear how clathrin rec
126 TPase dynamin promotes formation of clathrin-coated vesicles, but its mode of action is unresolved.
127 lins results in the accumulation of clathrin-coated vesicles, but not of clathrin-coated pits, at syn
131 incorporation into AP-1-containing clathrin-coated vesicles, caused loss of TGN localization and som
132 ) were required for plasma membrane clathrin-coated vesicle (CCV) budding and marked sites of CCV for
135 compared the protein composition of clathrin-coated vesicle (CCV) fractions from control and knocksid
137 cargo to visualize the formation of clathrin-coated vesicles (CCVs) at single CCPs with a time resolu
141 subcellular fractions enriched for clathrin-coated vesicles (CCVs) indicated that pip5k1 and pip5k2
143 n particular, it is unknown whether clathrin-coated vesicles (CCVs) participate in this transport ste
145 ng signals for packaging cargo into clathrin-coated vesicles (CCVs), and also facilitate down-regulat
146 ein-2 (AP2), a central component of clathrin-coated vesicles (CCVs), is pivotal in clathrin-mediated
147 entire population of intracellular clathrin-coated vesicles (CCVs), suggesting a more global functio
148 e adaptor protein (AP) complexes of clathrin-coated vesicles (CCVs), together with an FKBP and rapamy
149 eads to presynaptic accumulation of clathrin-coated vesicles (CCVs)-all without decreasing GABAergic
156 Endoplasmic Reticulum (ER)-derived COPII coated vesicles constitutively transport secretory cargo
157 endosome sorting process begins at clathrin-coated vesicles, depends on microtubule-dependent motili
158 or proteins, leading to cargo packaging into coated vesicles destined for the endolysosomal system.
160 on is to remove missorted proteins by small, coated vesicles during maturation of these spherical org
161 it the formation of clathrin-coated pits and coated vesicles during synaptic vesicle endocytosis.
164 ation protocols were used to obtain modified coated vesicle-enriched fractions, which were compared b
166 that the binding of TRAPPI to Sec23 marks a coated vesicle for fusion with another COPII vesicle or
167 t the TGN, resulting in p14 sorting into AP1-coated vesicles for anterograde TGN-plasma membrane tran
170 tic cells packages cargo proteins into COPII-coated vesicles for transport from the endoplasmic retic
174 be involved in both the initiation of COPII-coated vesicle formation and scission of the nascent ves
175 rate to increase the probability of clathrin-coated vesicle formation and to control the number, size
176 e 15) is well known for its role in clathrin-coated vesicle formation at the plasma membrane through
177 or protein-1 (AP1), responsible for clathrin-coated vesicle formation at the trans-Golgi, was selecti
181 at Eps15 plays an important role in clathrin-coated vesicle formation not only at the plasma membrane
182 own to depend on dynamin by rapidly blocking coated vesicle formation within seconds of dynasore addi
183 ruit accessory proteins involved in clathrin-coated vesicle formation, but the spectrum of known adap
184 lathrin adaptors are key factors in clathrin-coated vesicle formation, coupling clathrin to cargo and
185 red for multiple distinct stages of clathrin-coated vesicle formation, including coated pit formation
195 dynamin is required for budding of clathrin-coated vesicles from the plasma membrane, after which th
202 s in plants, but the involvement of clathrin-coated vesicles has been unclear; a new study provides s
203 ith the trans-Golgi and cytoplasmic clathrin-coated vesicles, implicating huntingtin in vesicle traff
205 ,K(+)-ATPase alpha(1)-subunits into clathrin-coated vesicles in cells transfected with the S11A mutan
206 ),K(+)-ATPase alpha(1)-subunit into clathrin-coated vesicles in cells transfected with WT and S18A ra
208 ed by ubiquitination, is present in clathrin-coated vesicles in epithelial cells that natively expres
212 ntact V1V0-ATPase from bovine brain clathrin-coated vesicles indicates that the structure of the isol
215 We found that when the budding of clathrin-coated vesicle is blocked without significantly affectin
216 laboratory indicates that the lifetime of a coated vesicle is extremely short, and assembly of nasce
219 tomer and formation of coat protein I (COPI)-coated vesicles is crucial to homeostasis in the early s
222 n-coated profiles (in this case, of clathrin-coated vesicles) is observed at inhibitory synapses of n
223 chain (CHC), the main component of clathrin-coated vesicles, is well characterized for its role in i
228 ity monitors that govern cargo packaging and coated vesicle maturation and as components of the fissi
229 lia, suggesting that disassembly of clathrin-coated vesicles may proceed through a partially uncoated
230 Also, our findings suggest that clathrin-coated vesicles may regulate Megatrachea turnover at the
239 verning the sorting of a SNARE into clathrin-coated vesicles, namely the direct recognition of the th
240 tures, and is enriched in placental clathrin-coated vesicles, new possibilities for Ced-6/Gulp operat
243 We examined the composition of clathrin-coated vesicles on an internal organelle responsible for
244 at AREs and caused aberrant accumulation of coated vesicles on AREs, suggesting a previously unrecog
245 pose that AP180 directs Vamp7B into clathrin-coated vesicles on contractile vacuoles, creating an eff
246 element-binding proteins (SREBPs) into COPII-coated vesicles on endoplasmic reticulum (ER) membranes
247 es offer a valuable system to study clathrin-coated vesicles on internal organelles within eukaryotic
250 of the hydrolase-MPR complexes into clathrin-coated vesicles or transport carriers (TCs) destined for
251 n, associates with a freshly budded clathrin-coated vesicle, or with an in vitro assembled clathrin c
255 a universal method for defining the clathrin-coated vesicle proteome and may be adapted for the analy
259 ociated with neck fission; 26 are enough for coated vesicle release in cells partially depleted of dy
260 Sorting of transmembrane cargo into clathrin-coated vesicles requires endocytic adaptors, yet RNA int
262 ) are too big to fit into conventional COPII-coated vesicles, so how are these bulky cargoes exported
263 ncreases the number of postsynaptic clathrin-coated vesicles, some of which traffic NMDA receptors, d
264 m conditions exhibited an increase in axonal coated vesicles, suggesting widespread neurotransmitter
265 we demonstrate the existence of mobile COPII-coated vesicles that completely encapsulate the cargo PC
267 lization on the plasma membrane and clathrin-coated vesicles that originated from the plasma membrane
269 EC23A is an essential component of the COPII-coated vesicles that transport secretory proteins from t
270 After the internalization of a clathrin-coated vesicle, the vesicle must uncoat to replenish the
272 roteins that influence the lifecycle of COPI-coated vesicles; this conclusion is supported by the obs
273 link ubiquitinated Notch ligands to Clathrin-coated vesicles through other Clathrin adapter proteins.
274 lytically supports the uncoating of clathrin-coated vesicles through recruitment of Hsc70 in an ATP h
275 te the intracellular trafficking of clathrin-coated vesicles through their interaction with several o
277 ind to the adaptor protein (AP) complexes of coated vesicles to modulate protein traffic, but the mol
278 mulate Gap1 incorporation into AP-1/clathrin-coated vesicles to promote Gap1 trafficking from endosom
279 rafficking of cargo via a subset of Clathrin-coated vesicles to selected membrane sites in retinal ro
280 ily protein driven, such as the formation of coated vesicles, to those that are primarily lipid drive
282 ur results reveal the importance of clathrin-coated vesicle trafficking in C. burnetii infection and
283 nclude effector endocytosis through clathrin-coated vesicle trafficking, defense signaling through me
288 ATPase (V-ATPase) from bovine brain clathrin coated vesicles was analyzed by electron microscopy and
290 in that plays major role in the formation of coated vesicles, was slower in rsw4 than in the control.
292 k and plasma membrane, and abundant clathrin coated vesicles were recruited to the region of nascent
293 rmore, mum failed to associate with clathrin-coated vesicles when receptor destabilization was inhibi
294 exit the endoplasmic reticulum (ER) in COPII-coated vesicles, whereas resident and misfolded proteins
296 a core component of coat protein complex II-coated vesicles, which transport secretory proteins from
297 y components are returned to the ER via COPI-coated vesicles, which undergo similar tethering and fus
298 ate secretory route are mediated by clathrin-coated vesicles, while the COat Protein I and II (COPI a
299 equired for the fusion of endocytic clathrin-coated vesicles with endosomes and also for subsequent p
300 omplexes) link the outer lattice of clathrin-coated vesicles with membrane-anchored cargo molecules.
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