ライフサイエンスコーパス: cockroach

1 IgE levels, and skin prick test responses to cockroach.

2 ed in multiple brain circuits of the Madeira cockroach.

3 he US population is sensitized to the German cockroach.

4 nonspecific transport of lipid molecules in cockroaches.

5 s of certain insects, such as honey bees and cockroaches.

6 ptera orders, with termites placed as social cockroaches.

7 humans and horses, but not with that used by cockroaches.

8 nlargement of hind legs, such as mantids and cockroaches.

9 type, with significant differences within WT cockroaches.

10 -offs for a relatively understudied Tribe of cockroaches.

11 ributed in intestinal tracts of termites and cockroaches.

12 mide plays a role in the circadian system of cockroaches.

13 ntrol feces over the fecal extract of axenic cockroaches.

14 In some insects (e.g., moths and cockroaches), a few glomeruli are sexually dimorphic and

15 st management is the recommended approach to cockroach abatement; however, it is costly and difficult

16 r the STAT4-null mutation were sensitized to cockroach Ag, challenged intratracheally 21 days later,

17 In this study, we report that, during cockroach Ag-induced allergic airway inflammation, Foxp3

18 Exposure to cockroach allergen (Bla g 1 at >or=2 U/g) modestly incre

19 report that, in the absence of Abr function, cockroach allergen (CRA)-immunized mice experienced a fa

20 into the airways of mice presensitized with cockroach allergen (CRAg), then allergic airway disease

21 ed a defect in CCR6-/- mice in response to a cockroach allergen airway challenge characterized by dec

22 Reductions in the levels of cockroach allergen and dust-mite allergen (Der f1) on th

23 We sought to document immune responses to cockroach allergen and provide direction for the develop

24 Bla g 2 is a major indoor cockroach allergen associated with the development of as

25 Here we review the current understanding of cockroach allergen biology and the demographics associat

26 The cockroach allergen Bla g 1 has multiple repeats of appro

27 Primary German cockroach allergen Bla g 1 is detected in 63% of homes a

28 tructure of a 1:1 complex between the German cockroach allergen Bla g 2 and the Fab' fragment of a mo

29 C3, that binds to the C-terminal lobe of the cockroach allergen Bla g 2 has been solved at 1.8 A reso

30 ng of N-linked glycans from natural purified cockroach allergen Bla g 2 was accomplished by MALDI-MS.

31 successful and failed attempts to lessen the cockroach allergen burden in homes.

32 The administration of cockroach allergen by means of SCIT is immunologically m

33 New practice parameters for cockroach allergen control were presented.

34 TGF-beta1 signaling activation in airways in cockroach allergen extract (CRE)-induced mouse models.

35 erize the trypsin-like proteinases in German cockroach allergen extracts used for clinical skin tests

36 sible for the proteolytic activity of German cockroach allergen have not been characterized.

37 ronmental variables (endotoxin; dog, cat and cockroach allergen in house dust) or variables that diff

38 Sensitivity to cockroach allergen is highly correlated with the develop

39 ilot studies suggest that immunotherapy with cockroach allergen is more likely to be effective with S

40 sought to test the hypotheses that domestic cockroach allergen measured prenatally would predict coc

41 ned A(2B) R expression by myeloid cells in a cockroach allergen model of murine asthma-like pulmonary

42 , D. pteronyssinus in the bed (P=0.007), and cockroach allergen on the bedroom floor (P<0.001).

43 Prenatal exposure to cockroach allergen was associated with a greater risk of

44 Following exposure to cockroach allergen, alpha-1,3-glucan-specific IgA-secret

45 Despite having cross-reactivity with cockroach allergen, we observed that non-cross-reactive

46 nce supporting the existence of a functional cockroach allergen-CD206 axis in human fibrocytes, sugge

47 In cockroach allergen-induced airway responses, both intrap

48 basis for studying the mechanisms regarding cockroach allergen-induced allergic sensitization and as

49 ill discuss the epidemiological evidence for cockroach allergen-induced asthma, cockroach allergens,

50 ined the role of CxCR4 in the development of cockroach allergen-induced inflammation and airway hyper

51 ockroach allergens, the mechanisms regarding cockroach allergen-induced innate immune responses, and

52 posure demonstrated bystander suppression of cockroach allergen-mediated airway eosinophilia.

53 ted house dust protects against ovalbumin or cockroach allergen-mediated airway pathology.

54 In cockroach allergen-sensitized mice, ethanol triggered as

55 comes and mouse allergen were independent of cockroach allergen.

56 ly associated with poor asthma outcomes than cockroach allergen.

57 pregulated on dendritic cells in response to cockroach allergen.

58 meters of two groups of mice sensitized with cockroach allergen.

59 1,3-glucan binds an Enterobacter species and cockroach allergen.

60 re associated with lower risk of asthma (for cockroach allergen: odds ratio per interquartile range i

61 ced by a house dust extract (HDE) containing cockroach allergens and endotoxin.

62 ith high morbidity and healthcare costs, and cockroach allergens are an established cause of urban pe

63 medial sanitation, large-scale reductions in cockroach allergens below clinically relevant thresholds

64 Although successful removal of cockroach allergens from the infested environment has be

65 Cockroach allergens identification and their expression

66 Sensitization to cockroach allergens is a major risk factor for asthma.

67 Outbred mice were exposed to cockroach allergens on Days 0 and 14; and on Day 21, mic

68 ested to be important for the penetration of cockroach allergens through epithelial cells to mediate

69 The binding activity of cockroach allergens to CD206 was determined by solid-pha

70 to investigate the functional interaction of cockroach allergens with CD206 in fibrocytes.

71 community with high levels of both mouse and cockroach allergens, mouse allergen appears to be more s

72 dence for cockroach allergen-induced asthma, cockroach allergens, the mechanisms regarding cockroach

73 regulation, and developmental expression of cockroach allergens, thus providing insight into their f

74 nd endotoxin, house dust mite, cat, dog, and cockroach allergens.

75 Preincubation of sera from cockroach-allergic subjects with WbGST partially deplete

76 ortant information relevant to understanding cockroach allergies and their treatment.

77 jor targets of IgE responses associated with cockroach allergies.

78 Cockroach allergy is a key contributor to asthma morbidi

79 -glucan results in suppressed development of cockroach allergy via pulmonary alpha-1,3-glucan-specifi

80 ion for the development of immunotherapy for cockroach allergy.

81 ing Enterobacter (MK7) are protected against cockroach allergy.

82 eonates and were no longer protected against cockroach allergy.

83 ficantly higher odds of sensitization to the cockroach and cat allergens compared to those without gl

84 We conclude that cockroach and cat allergens may contribute to asthma mor

85 d analysis of the NADPHd architecture in the cockroach and comparison with that in the locust.

86 ases exposure to indoor allergens, including cockroach and dust-mite allergens, resulting in reduced

87 Sera from patients allergic to cockroach and mite were tested for IgE reactivity to the

88 r sensitization to inhaled allergens such as cockroach and moth using ImmunoCAP.

89 tized to common inhaled allergens, including cockroach and moth.

90 Cockroach and mouse allergens have both been implicated

91 urban neighborhoods, pest allergens, such as cockroach and mouse, are present in high concentrations

92 o related polyneopteran species, the Madeira cockroach and the desert locust.

93 A serum raised against octopamine reveals in cockroaches and honey bees structurally comparable syste

94 te that the lobelet is present only in basal cockroaches and in termites, supporting existing theorie

95 III Kenyon cell morphologies described from cockroaches and termites.

96 mmunoreactive organization in honey bees and cockroaches and the suggested roles of octopamine in sen

97 s (house cricket) and Periplaneta americana (cockroach), and re-examined its role in Drosophila melan

98 inhalant allergens from house dust mites and cockroaches, and lipocalins.

99 ng airborne viruses, smoke, indoor dampness, cockroaches, and poor access to health care.

100 as both a phagostimulant and deterrent in GA cockroaches, and this newly acquired peripheral taste se

101 ethnicity; participant age; dog(s), cat(s), cockroaches, and/or smoker(s) in the home; and carpeted

102 und in mice sensitized and rechallenged with cockroach antigen (CRA).

103 l of allergic airway inflammation induced by cockroach antigen (CRA).

104 e promoted allergic sensitization to inhaled cockroach antigen in the absence but not the presence of

105 n sensitized and chronically challenged with cockroach antigen to induce chronic airway disease.

106 season, maternal atopy, education, race, and cockroach antigen.

107 ments infected mice were exposed to low-dose cockroach antigen.

108 Cockroaches are a group of insects that evolved early in

109 The fat bodies of most cockroaches are inhabited by Blattabacterium, which are

110 y responses to fungi-, house dust mite-, and cockroach-associated allergens in mouse models.

111 were sensitized to house dust mite (HDM) or cockroach at day 0, treated with IL-6R inhibitors at day

112 s were found between overcrowding, molds and cockroaches at home, and atopic multiple-trigger wheeze

113 ed for mouse (Mus m 1), dust mite (Der p 1), cockroach (Bla g 1), and mold (Alternaria mix) allergens

114 major glutathione-S transferase allergen of cockroach (Bla g 5) and the glutathione-S transferase of

115 The allergenicity of several German cockroach (Bla-g) antigens at the level of IgE responses

116 tics of sprawled posture insects such as the cockroach Blaberus discoidalis.

117 servations of kinematics and dynamics of the cockroach Blaberus discoidalis; in particular, motoneuro

118 sfully used the DNA origami robots in living cockroaches (Blaberus discoidalis) to control a molecule

119 om central-complex neurons in freely walking cockroaches (Blaberus discoidalis), we identified classe

120 rection coding in the central complex of the cockroach, Blaberus discoidalis.

121 -gated sodium channel BgNaV1 from the German cockroach Blattella germanica by shifting the threshold

122 ble trait that evolved in a number of German cockroach (Blattella germanica L.) populations in respon

123 We provisioned nymphs from three German cockroach (Blattella germanica L.) populations, which di

124 Allergy to the German cockroach (Blattella germanica) is a significant asthma

125 lar experimental manipulations of the German cockroach (Blattella germanica), carpenter ant (Camponot

126 Cockroach (Blattella germanica), dust mite (Dermatophago

127 The sex pheromone of the German cockroach, Blattella germanica, has been characterized a

128 Aggregation of the German cockroach, Blattella germanica, is regulated by fecal ag

129 distribution of MIP-related peptides in the cockroach brain.

130 ing partial sequences obtained from purified cockroach bursicon, we identified the Drosophila melanog

131 mparable with high-performing organisms like cockroaches but suffer significant performance loss on f

132 ied IgE directed against house dust mite and cockroach, but not against timothy grass, the latter wit

133 lations of exposure to allergens (dust mite, cockroach, cat, and dog), nitrogen dioxide, and mold wit

134 Indoor aeroallergens, including rat, mouse, cockroach, cat, dog, and dust mites, measured in dust sa

135 t choice in an identified neuron (6m) of the cockroach cercal sensory system.

136 tropicalis, cat, German cockroach, Oriental cockroach, codfish, crab, shrimp, and cheese (all P </=

137 e unconditioned stimulus of saline solution, cockroaches conditioned in the early subjective night sh

138 ng the largest and most abundant of the wood cockroaches, constituting >50% of the biomass of the woo

139 g insect allergens from house dust mites and cockroaches contribute to allergic inflammatory diseases

140 al biology and their relationship to current cockroach control strategies.

141 ects of venom that wasps use in preying upon cockroaches could provide insights into this problem.

142 rial testing the use of insecticidal bait on cockroach counts and asthma morbidity.

143 evices to enter a vertically confined space, cockroaches crawled at velocities approaching 60 cms(-1)

144 n this field have been performed in locusts, cockroaches, crickets, and stick insects, the examples w

145 In both wild-type and glucose-averse (GA) cockroaches, D-fructose and D-glucose stimulated sugar-g

146 In contrast, in GA cockroaches, D-glucose also stimulated bitter-GRNs and s

147 ment in developing embryos of the viviparous cockroach Diploptera punctata influences how quickly neo

148 sequence tags from the corpora allata of the cockroach Diploptera punctata yielded a new cytochrome P

149 hat act as fecal aggregation agents and that cockroaches discriminate among the complex odors that em

150 rdless of specific sensitization) dust mite, cockroach, dog, and dampness-related agents.

151 n testing was performed for Alternaria, cat, cockroach, dog, Dermatophagoides farinae (Der F), Short

152 were measured for Alternaria alternata, cat, cockroach, dog, Dermatophagoides farinae, short ragweed,

153 f common aeroallergens including Alternaria, cockroach, dog, dust mite, cat, mouse, and rat allergens

154 s of these neurons have now been recorded in cockroaches during walking.

155 months of age were analyzed for total, anti-cockroach, dust mite, and mouse IgE.

156 hat characterizes olfactory communication in cockroaches: Each long-range sex pheromone identified to

157 d is widely available, resulted in sustained cockroach elimination over 12 months and was associated

158 by the mandibular glands, as occurs in early cockroach embryos.

159 ediated by PaNav1 channels from the American cockroach even though their domain II paddle motifs are

160 Cockroach exoskeletons provided biological inspiration f

161 ations for allergic disease, and standardize cockroach exposure assays.

162 e intervention, insecticidal bait, to reduce cockroach exposure in the home of children with asthma i

163 Cockroach exposure is a major risk factor for the develo

164 The impact of reducing cockroach exposure on asthma outcomes is not known.

165 AND We developed and used a 12 week model of cockroach extract (CE)-mediated AHR, airway inflammation

166 tized and challenged with ovalbumin (OVA) or cockroach extract (CE).

167 virus of mice [PVM]) and exposed to low-dose cockroach extract (CRE) in early and later life, and air

168 were exposed to pneumonia virus of mice and cockroach extract in early and later life and then chall

169 Biting flies, cockroaches, filth flies, and triatomid bugs represent a

170 ric acids were associated with nBla g 1 from cockroach frass.

171 offspring-viability assumption in Tanzanian cockroaches, fruit flies, pipefish, wild mallards, and f

172 an area in which (1) the climate discourages cockroach, fungal, and mite growth and (2) dander allerg

173 mate-immunoreactive neurons in honeybees and cockroaches further suggests that neural arrangements pr

174 In this study we asked whether German cockroach (GC) feces (frass) could initiate an innate im

175 We recently identified that German cockroach (GC) frass contains a TLR2 ligand allowing us

176 German cockroach (GCr) allergen extracts are complex and hetero

177 tic behaviour between two species of hissing cockroaches, Gromphadorhina oblongonota and Aeluropoda i

178 Cockroaches harbor the obligate flavobacterial endosymbi

179 A new study of the escape behavior of the cockroach has found that its spatial variability is base

180 Like many animals, the cockroach has two En paralogs, Pa-En1 and Pa-En2.

181 lt of toxic baits, populations of the German cockroach have rapidly evolved an adaptive behavioral av

182 For nearly a half century, cockroaches have been recognized as a major cause of ast

183 glucose-containing bait, glucose-averse (GA) cockroaches have lower performance than wild-type (WT) c

184 Studies, particularly with termites and cockroaches, have focused on the nutritional contributio

185 of Burkholderia-infected Madagascar hissing cockroaches (HCs) increases their survival.

186 previously unknown pheromonal structure for cockroaches, highlighting the great chemical diversity t

187 ed that A. compressa larvae impregnate their cockroach hosts from inside with large amounts of an ora

188 ounter during their development inside their cockroach hosts.

189 lted in significant changes from baseline in cockroach IgE, IgG4, and blocking antibody levels.

190 The safety profile of cockroach immunotherapy was reassuring in all studies.

191 t of allergen-specific IgE to dust mites and cockroach in plasma.

192 son of birth, PM2.5, breastfeeding, mold and cockroaches in home, and distance from highway.

193 s have lower performance than wild-type (WT) cockroaches in several fitness-determining traits.

194 Wood cockroaches in the genus Parcoblatta, comprising 12 spec

195 ere we find that extracts from dust mite and cockroach induce sustained Ca(2+) elevations in AECs thr

196 Both HDM and cockroach induced a type 2/type 17 cytokine profile and

197 sed IL-6 expression in the airways, but only cockroach induced sIL-6R expression.

198 In contrast, cockroach-induced inflammation involved activation of IL

199 a T-cell deficiency significantly attenuated cockroach-induced inflammation.

200 This cockroach is a major cause of allergic disease and serve

201 Sensitization to cockroach is one of the strongest identified risk factor

202 Exposure to cockroaches is an important asthma trigger, particularly

203 mite, orchard grass, ragweed, wormwood, dog, cockroach, Japan cedar).

204 Isolated cockroach legs also had gravity-independent rest positio

205 We show here that the ability of the cockroach Leucophaea maderae to acquire olfactory memori

206 the distribution of MIPs in the brain of the cockroach Leucophaea maderae.

207 hykinin-related peptides in the brain of the cockroach, Leucophaea maderae, and the locust, Locusta m

208 Cockroach, like other allergens, contains trypsin-like e

209 to that studied in other orthopteroid taxa (cockroaches, locusts, crickets, tettigoniids).

210 e in other insects of the taxon Dictyoptera (cockroaches, mantises, and termites).

211 ssociation with asthma, and sensitization to cockroach mediated 13% to 20% of the association with fo

212 Higher house dust concentrations of cockroach, mouse, and cat allergens in the first 3 years

213 In contrast, first-year exposure to cockroach, mouse, and cat allergens was negatively assoc

214 Exposure to certain allergens (cockroach, mouse, dust mite) was significantly associate

215 Here, we describe a substructure of the cockroach mushroom bodies composed of a previously unrec

216 We show that in the cockroach mushroom bodies there are two types of plastic

217 In the cockroach mushroom bodies, particularly dense staining i

218 ation of ovarian apoptosis in females of the cockroach Nauphoeta cinerea, an insect with reproductive

219 Feces from axenic cockroaches (no microorganisms in the alimentary tract)

220 ria alternata, egg, peanut, milk, and German cockroach) obtained from 594 children at age 2 years.

221 ns between IgE subtypes and glaucoma for the cockroach (odds ratio [OR] = 2.78; 95% CI = 1.34, 5.76),

222 ith at least one neuropil not present in the cockroach or locust.

223 B, the presence of IgE responses specific to cockroach or moth by ImmunoCAP were found in 27.8% or 52

224 oides farina, Blomia tropicalis, cat, German cockroach, Oriental cockroach, codfish, crab, shrimp, an

225 of C. clypeatus and the mushroom body of the cockroach P. americana reveal in both a layered motif pr

226 n to mites (P < 0.001), animals (P = 0.001), cockroaches (P < 0.001), and foods (P = 0.042), and furt

227 The broad wood cockroach, Parcoblatta lata, is among the largest and mo

228 The L. maderae enzyme cleaved the cockroach peptide LemTRP-1 and the mammalian NEP substra

229 oteinase previously cloned from the American cockroach (Per a 10).

230 The mushroom bodies of the cockroach Periplaneta americana are made up of intrinsic

231 from homogenates of 2,850 nerve cords of the cockroach Periplaneta americana by using high performanc

232 red whole-cell patch-clamp recordings in the cockroach Periplaneta americana to characterize synaptic

233 sp larvae develop on and inside the American cockroach Periplaneta americana, a host that can harbor

234 In the antennal lobe of the cockroach Periplaneta americana, gamma-aminobutyric acid

235 ion with the mushroom body of an insect, the cockroach Periplaneta americana.

236 al unpaired median neurons from the American cockroach Periplaneta americana.

237 ct, we repeated some of these experiments in cockroach (Periplaneta americana) and mouse.

238 arcodes in a global urban pest, the American cockroach (Periplaneta americana).

239 embranes prepared from the heads of American cockroaches (Periplaneta americana) confirmed the import

240 The cockroach, Periplaneta americana represents a basal inse

241 ennal grooming was prevented in the American cockroach, Periplaneta americana, field emission gun sca

242 ch suggest that it may provide a new tool in cockroach population detection, monitoring, and control.

243 ynthesized, could be deployed for monitoring cockroach populations.

244 ecently been realized through suppression of cockroach populations.

245 sistant and susceptible house fly and German cockroach populations.

246 Several cockroach-produced allergens have been identified and ch

247 Cockroaches rapidly traversed crevices in 300-800 ms by

248 in New Orleans and to examine the impact of cockroach reduction on asthma outcomes.

249 The circadian pacemaker of the Madeira cockroach, Rhyparobia (Leucophaea) maderae, is located i

250 es of human running, a horse trotting, and a cockroach running.

251 onclusion, IgE sensitization to mites, pets, cockroaches, seafood, and cheese, respectively, is signi

252 ntestinal communities in the closely related cockroaches seem to be shaped primarily by the selective

253 Cockroach sensitization (C+) might be a proxy for microb

254 Several genes have been associated with cockroach sensitization and asthma-related phenotypes.

255 Bla g 2 in prenatal kitchen dust predicted cockroach sensitization at the ages of 5 to 7 years (adj

256 h allergen measured prenatally would predict cockroach sensitization in early childhood and that this

257 Cockroach sensitization is an important risk factor for

258 immune responses, and the genetic basis for cockroach sensitization.

259 ant role in conferring the susceptibility to cockroach sensitization.

260 Cockroach sensitization/exposure was only associated wit

261 were mouse sensitized/exposed, and 41% were cockroach sensitized/exposed based on bedroom floor expo

262 Asthmatic and nonasthmatic cockroach-sensitized individuals exhibit similar TH 2-po

263 wo odors (peppermint and vanilla), untrained cockroaches showed a clear preference for vanilla at all

264 randomized, double-blind biomarker study of cockroach SLIT versus placebo in adults; (3) a randomize

265 , double-blind biomarker study of 2 doses of cockroach SLIT versus placebo in children; and (4) an op

266 e octapeptide segment IFGSFFTL in IIIS6 of a cockroach sodium channel BgNa(V), besides Ser_3i15 and L

267 III (IIIS6) abolished the sensitivity of the cockroach sodium channel expressed in Xenopus laevis ooc

268 sensitive current in a splice variant of the cockroach sodium channel gene BgNa(v) (formerly para(CSM

269 aracterized 20 splice variants of the German cockroach sodium channel gene BgNa(v).

270 segments 3 and 4 of domain III in the German cockroach sodium channel gene, para(CSMA).

271 urrents and antagonizes the action of BTX on cockroach sodium channels, suggesting that it also binds

272 IVS6, are all critical for BTG 502 action on cockroach sodium channels.

273 s utility in monitoring several endemic wood cockroach species in red-cockaded woodpecker habitats.

274 ecological range and global distribution of cockroach species.

275 o (aOR) 2.08 (1.38, 3.15)]; M. perstans with cockroach-specific IgE [aGMR 2.37 (1.39, 4.06)], A. lumb

276 s) found a significantly greater increase in cockroach-specific IgE levels between the active and pla

277 a health across a range of outcomes, whereas cockroach-specific IgE levels were not.

278 PT; median Dermatophagoides-specific IgE and cockroach-specific IgE were 1440 and 220 ng/ml, respecti

279 .92; P < .0001) and a trend toward increased cockroach-specific IgG4 levels in actively treated subje

280 Our sampling effort generated 284 cockroach specimens, most from New York City, plus 15 ad

281 susceptible ACY and resistant Apyr-R German cockroach strains using PCR-selected subtractive hybridi

282 an open-label safety and biomarker study of cockroach subcutaneous immunotherapy (SCIT) in adults.

283 an open-label study to assess the safety of cockroach sublingual immunotherapy (SLIT) in adults and

284 of the locust than the more closely related cockroach suggesting that the sensory ecology plays a st

285 , intervention homes had significantly fewer cockroaches than did control homes (mean change in cockr

286 different serine proteinases from the German cockroach that may, via PAR2 activation, play different

287 association with Blattabacterium has allowed cockroaches to subsist successfully on nitrogen-poor die

288 Exoskeletal strength allowed cockroaches to withstand forces 300 times body weight wh

289 aches than did control homes (mean change in cockroaches trapped, 13.14; 95% CI, 6.88-19.39; P < .01)

290 Within the Madagascan giant hissing cockroaches (Tribe Gromphadorhini) differences in morpho

291 Cockroaches, unlike most terrestrial insects, excrete wa

292 Dc1a promotes opening of German cockroach voltage-gated sodium (Nav) channels (BgNav1),

293 performed tetrode recordings from the CC of cockroaches walking in place on a slippery surface.

294 ugh sensitization/exposure to both mouse and cockroach was generally associated with worse asthma, mo

295 ribe a food-hygienic strategy of the emerald cockroach wasp Ampulex compressa.

296 mide plays a role in the circadian system of cockroaches, we studied SIFamide in Rhyparobia (= Leucop

297 within heterogeneous populations, WT German cockroaches will over time prevail in abundance over GA

298 We challenged cockroaches with horizontal crevices smaller than a quar

299 Inoculation of axenic cockroaches with individual bacterial taxa significantly

300 All cockroaches, with the exception of one cave-dwelling gen