ライフサイエンスコーパス: cocrystallization

1 's crystal structure through methods such as cocrystallization.

2 crystals with CD, and the other obtained by cocrystallization.

3 ty of using pure solvents as matrix to avoid cocrystallization.

4 heir enzyme-bound complexes were obtained by cocrystallization.

5 too large and too flexible to lend itself to cocrystallization.

6 complex ESA/Dic/Nps, obtained by competitive cocrystallization (2.19 A) and through a displacement ex

7 The decrease of energy upon cocrystallization agrees with the exothermic mixing of N

8 ows that host-guest interactions and racemic cocrystallization allow for controlling the solid state

9 other interactions can contribute equally to cocrystallization, allowing superlattice formation to be

10 ing and strengthening of hydrogen bonds upon cocrystallization, analogous to water freezing.

11 zyme mechanisms and as potential ligands for cocrystallization and as lead structures for development

12 oach to understand the effect of solvents on cocrystallization and codissolution of chemically dissim

13 f lipid extracts, which promotes homogeneous cocrystallization and enables relative quantification by

14 these channels are maintained and enable the cocrystallization and intercalation of PCBM.

15 Crystals were obtained by cocrystallization and were isomorphous with respect to t

16 are relevant for understanding the nature of cocrystallization and why some molecules are prolific co

17 tive site has been established by successful cocrystallization and X-ray analysis of potent inhibitor

18 gnificant differences in analyte extraction, cocrystallization, and ionization across a sample.

19 Whereas cocrystallizations are frequently applied to structure d

20 Cocrystallization between analyte and matrix is required

21 This type of cocrystallization causes an alignment shift to satisfy c

22 p an affinity purification method and screen cocrystallization conditions for the chemokine receptor

23 demonstrated for a blend of PE and iPP that cocrystallization effects are minimal in solvents such a

24 were formed by direct adsorption rather than cocrystallization, emphasizing the unusually robust natu

25 A cocrystallization experiment in which a dodecamer-formin

26 Cocrystallization experiments revealed that these compou

27 R ligand-binding domain have been studied by cocrystallization experiments using a coactivator-like p

28 ge, digestion, desalting, and matrix/analyte cocrystallization for MALDI-MS analyses.

29 Cocrystallization in colloidal mixtures yields anisotrop

30 isolate a metastable polymorph formed during cocrystallization in three-dimensional crystallization.

31 Cocrystallization of 14a with the amino terminal domains

32 Cocrystallization of 2 with the human DAAO enzyme define

33 Interestingly, cocrystallization of 46a,b with the RXRalpha protein gen

34 emic crystallization, a method that involves cocrystallization of a chiral molecule with its mirror i

35 The possibility of cocrystallization of an active soluble eukaryotic 14 alp

36 zation mass spectrometry (MALDI-MS) requires cocrystallization of analyte with a large excess of matr

37 Cocrystallization of Aurora-A with 40c (CCT137444) provi

38 Cocrystallization of DNMT3L with the tail of histone H3

39 Cocrystallization of Escherichia coli wild-type glycogen

40 Analysis following cocrystallization of four ligand complexes with AChBP sh

41 Cocrystallization of GPRTase with immucillinGP led unexp

42 Our approach involves multicomponent cocrystallization of hydrochloride salts, wherein strong

43 phosphorylation of isocitrate dehydrogenase, cocrystallization of isocitrate dehydrogenase and isocit

44 lly binds to the ESCRT-III subunit Did2, and cocrystallization of Ist1NTD with a Did2 fragment shows

45 proach to search for new chemical series and cocrystallization of key analogues to guide the optimiza

46 Cocrystallization of La(3+)-bound enzymes with Man9GlcNA

47 Cocrystallization of N1b1b2 with Tuftsin, a peptide mimi

48 The ordered cocrystallization of nanoparticles into binary superlatt

49 d drug design strategy, which was enabled by cocrystallization of several analogues with BioA.

50 que TCR-pMHC complexes have been determined, cocrystallization of soluble TCR and pMHC remains a majo

51 Cocrystallization of T4-Pdg with substrate DNA has shown

52 Finally, the cocrystallization of the best optimized analogue with Et

53 Cocrystallization of the C-3 diastereomeric 3-amidotetra

54 Cocrystallization of the cytochrome bc1 complex with the

55 Cocrystallization of the enzyme from Torpedo californica

56 alic acid binding site on HN was revealed by cocrystallization of the HN with a thiosialoside Neu5Ac-

57 Cocrystallization of the inactive GS mutant E377A with s

58 Cocrystallization of the isomer with a carboxylic acid r

59 Cocrystallization of the nebulette SH3 domain with the i

60 Cocrystallization of the trimeric ERalpha/14-3-3/FC comp

61 Cocrystallization of these two inhibitors with the conde

62 that the small molecule malonic acid enables cocrystallization of this mixed function oxidase with th

63 2 glutamate (hmGlu2) site was established by cocrystallization of this molecule with the amino termin

64 in the case of MALDI-MS, matrix and analyte cocrystallization on target.

65 is to wash matrix/sample spots after peptide cocrystallization on the MALDI plate with deionized wate

66 Cocrystallization only succeeded with extremely high con

67 line ligand-protein complexes were formed by cocrystallization or by the soaking in/soaking out metho

68 e a structure with bound ligand using either cocrystallization or soaking crystals with cysteine reve

69 nd improved complex formation with potential cocrystallization partners such as conformationally sens

70 role of energetic and kinetic factors in the cocrystallization process.

71 ble of forming hydrogen bonds to amplify the cocrystallization processes.

72 ing product diversity during mechanochemical cocrystallization reactions.

73 This new binding mode was validated by cocrystallization, showing all binding interactions typi

74 Structural analysis and cocrystallization studies identify three putative solute

75 6-like antibodies, as well as constructs for cocrystallization studies.

76 ecent insights from pharmacophore models and cocrystallization studies.

77 nylguanidines has been investigated by X-ray cocrystallization studies.

78 appropriate aqueous solubility to facilitate cocrystallization studies.

79 Here through cocrystallization the density, oxygen balance, and stabi

80 study represents the first application of a cocrystallization to confirm the relative configuration

81 Consequently, a strategy based on a cocrystallization was developed to generate single cryst

82 Although cocrystallization was unsuccessful, a new crystal form o

83 e complex with the inhibitor was obtained by cocrystallization, whereas that with the substrate was o

84 (15) has been resolved into enantiomers via cocrystallization with (-)-N-benzylcinchonidinium chlori

85 lation, and enzymatic digestion, followed by cocrystallization with a MALDI matrix and analysis of th

86 rystals, the new structures are derived from cocrystallization with Ca(2+), Mg(2+), or Mn(2+).

87 its polyspecific binding behavior have made cocrystallization with drugs challenging.

88 nous HLA-DR/peptide complexes may facilitate cocrystallization with T cell receptors as well as other

89 of two of these inhibitors was determined by cocrystallization with TdT, explaining why these compoun

90 orB likely binds host mitochondrial ATP, and cocrystallization with the ATP analog AMP-PNP suggests t

91 ansition-state analogue inhibitors permitted cocrystallization with the malarial enzyme and refinemen

92 Cocrystallization with two agonists possessing distinct

93 essing and/or the storage of insulin and its cocrystallization with Zn(2)(+), and 2) these increases