ライフサイエンスコーパス: coelenterazine

1 tive decarboxylation of the bound substrate, coelenterazine.

2 lungs of living mice tail-vein injected with coelenterazine.

3 escence following systemic administration of coelenterazine.

4 bic core cavity that accommodates the ligand coelenterazine-2-hydroperoxide.

5 n bond donor-acceptor separations around the coelenterazine-2-hydroperoxy substrate, initiated by sma

6 protein that utilizes its natural substrate coelenterazine, a benefit of which is demonstrated at va

7 asis for this effect were also explored with coelenterazine, a Pgp substrate.

8 bioluminescence and for the extensive use of coelenterazine among marine organisms.

9 of red-shifted luciferins based on synthetic coelenterazine analogs and corresponding mutants of Nano

10 Eleven new coelenterazine analogs containing the 3,7-dihydroimidazo

11 aired two aequorin conjugates with different coelenterazine analogues and then resolved the two signa

12 Interestingly, coelenterazine analogues share structural and physiochem

13 quorea victoria is unable to produce its own coelenterazine and is dependent on a dietary supply of t

14 Therefore, using coelenterazine and noninvasive bioluminescence imaging i

15 pecific antibody followed by the addition of coelenterazine and signal acquisition using a luminomete

16 rotein aequorin, which contains the molecule coelenterazine as a prosthetic group and shows considera

17 The molecule also contains coelenterazine as its chromophoric ligand.

18 properties and applications of d-luciferin, coelenterazine, bacterial, Cypridina and dinoflagellate

19 analysis of the hydrogen bond network in the coelenterazine binding cavity, it is proposed that the t

20 f enzyme and vascular systems indicated that coelenterazine chemiluminescence is a sensitive marker f

21 scular O(2)( *-) production, as indicated by coelenterazine chemiluminescence, were significantly inc

22 eins catalyses the production of light using coelenterazine disulfate and ATP.

23 nescent reaction using ATP and the substrate coelenterazine disulfate.

24 L) does not serve as a substrate for RL, and coelenterazine does not serve as a substrate for FL eith

25 Also the H-bonding between His-22 and the coelenterazine found in the active photoprotein is prese

26 unable to produce light unless provided with coelenterazine from an external source.

27 In contrast, the chemiluminescent probe coelenterazine had no significant effect on xanthine oxi

28 zyme/protein (RL) by injecting the substrate coelenterazine in living mice.

29 e catalyzes the degradation of its substrate coelenterazine in the presence of molecular oxygen, resu

30 fter intratumoral injection as determined by coelenterazine injection followed by imaging.

31 Coelenterazine is widely distributed among marine organi

32 Although coelenterazine itself does not enter cells because of Pg

33 (within 2-4 min) upon re-addition of Ca++ to coelenterazine-loaded cells, a finding consistent with v

34 In addition to the native coelenterazine luciferase substrate, we used the synthet

35 transfected with a codon-humanized Rluc show coelenterazine-mediated bioluminescence in a highly MDR1

36 Tyr-138 hydrogen bonded to the coelenterazine N1-atom in unreacted obelin is moved away

37 injection of rGluc followed by its substrate coelenterazine, non-invasive visualization of tumor vasc

38 in the absence of calcium by incubation with coelenterazine, oxygen and a thiol agent.

39 animals, wherein Pgp-mediated alterations in coelenterazine permeability may impact results.

40 Upon the addition of the substrate coelenterazine, the energy produced by Luc8 was nonradia

41 es are exposed to the luciferase's substrate coelenterazine, the energy released by substrate catabol

42 uorin, light is produced by the oxidation of coelenterazine, the luciferin used by at least seven mar

43 o catalyze the oxidation of the chromophore, coelenterazine, to coelenteramide with the release of li

44 duction, little is known about mechanisms of coelenterazine transport and cell permeation.

45 he majority of chemiluminescence produced by coelenterazine treatment of ERaeq-expressing 293 cells w

46 n, and following addition of the chromophore coelenterazine underwent Ca(++)-activated chemiluminesce

47 herein present the first structures for any coelenterazine-using luciferase.

48 substrate, we used the synthetic derivative coelenterazine-v, which further red-shifts the emission

49 erase-luciferin and Rluc: Renilla luciferase-coelenterazine), we tested the efficacy of TRAIL using r

50 s been no evidence to indicate the origin of coelenterazine within the phylum Cnidaria.