ライフサイエンスコーパス: coexpression

1 emble with Cav2.2 channels upon heterologous coexpression.

2 less than 4 wk to 10 wk on average with HGGT coexpression.

3 subphenotypes with novel patterns of marker coexpression.

4 by specific patterns of transcription factor coexpression.

5 entiation, and increased inhibitory receptor coexpression.

6 nvestigated the impact of RUNX1 and FLT3-ITD coexpression.

7 Our findings indicate that mRNA coexpression abnormalities may serve as a promising mech

8 We further show that KCNE1 coexpression abolishes the PUFA effect on Kv7.1 by promo

9 In this study, transcript coexpression analyses revealed positive correlations amo

10 ght gene association methods for genome-wide coexpression analysis between each TF and all other geno

11 Coexpression analysis coupled with enrichment analysis r

12 ranscriptomic data, we conducted genome-wide coexpression analysis for HEY2, which uncovered KCNIP2,

13 Recently, differential coexpression analysis has been developed to study the re

14 FGF1-stratified coexpression analysis in two separate collections of hum

15 Coexpression analysis indicated the presence of gene clu

16 Coexpression analysis of differentially expressed genes

17 Coexpression analysis of the available transcriptomic da

18 Taken together, differential coexpression analysis provides a new strategy for analyz

19 APOL1 tubulointerstitial coexpression analysis showed coexpression of APOL1 mRNA

20 Protein-coding gene-lincRNA coexpression analysis suggested an involvement of lincRN

21 ed differential expression analysis and gene coexpression analysis to identify activity-dependent or

22 We further use coexpression analysis to identify genes of unknown funct

23 a combination of untargeted metabolomics and coexpression analysis to uncover the complete biosynthet

24 Although coexpression analysis via pair-wise expression correlati

25 Using gene coexpression analysis, we identified 2 modules (turquois

26 th these metastable proteins by using a gene coexpression analysis.

27 esponses to P. syringae through differential coexpression analysis.

28 Limited coexpression and colocalization of the D1R and D2R prote

29 However, in contrast to Eci2, in silico gene coexpression and enrichment analysis for Eci3 in kidney

30 Gene coexpression and phylogenomics analyses showed that cons

31 man cutaneous wounds showed higher p53-SIVA1 coexpression and proliferation 7 days after injury in ES

32 Using a coexpression and sequence-based strategy, we predicted s

33 le pair of cells in the animal, with limited coexpression, and only a fraction of pharyngeal neurons

34 Here we report that TWIST1 and HOXA9 coexpression are reactivated in mouse and human primary

35 ght the emerging recognition of MYC and BCL2 coexpression as the most robust predictor of DLBCL outco

36 HIV-1-targeted cells with CD4+beta7hi/CCR5+ coexpression, as well as increased activation.

37 gene interaction or any other correlation or coexpression based networks.

38 We also observed extensive differential coexpression between genes within the same metabolic pat

39 interaction: two genes (ceRNAs) can achieve coexpression by competing for a pool of common targeting

40 databases (e.g. for protein localization and coexpression) can be mined to provide clues.

41 We used an RNA sequencing-based approach and coexpression correlation analysis to identify several ca

42 Our diurnal coexpression data capture functional relationships estab

43 tein-protein interaction network prediction, coexpression data mining, and phylogenetic profiling all

44 A genome-wide mRNA-based coexpression data set was generated based on quality con

45 evaluate this hypothesis, we used 10 global coexpression data sets, each a meta-analysis of hundreds

46 he iPANDA method combines precalculated gene coexpression data with gene importance factors based on

47 The data were integrated into a large-scale coexpression database ( www.gene2function.de), enabling

48 LMP1 and LMP2A coexpression did not enhance cell growth, with a moderat

49 nlike in other developmental contexts, their coexpression does not rely on the same regulatory mechan

50 ure of bispecific IgG assembled in vivo upon coexpression down to 1% impurity.

51 ctors that may be regulators of differential coexpression during plant immune responses.

52 Upon coexpression, FVIIa Q64C and sTF G109C spontaneously ass

53 om these developmental stages, we obtained a coexpression gene network that highlights interactions b

54 Gene Link Inspector Through Tissue-specific coExpRession (GLITTER), a web-based application for asse

55 al genes was revealed by their assignment to coexpression groups with partially overlapping profiles

56 classified 22 857 genes as variable (79%; 22 coexpression groups) or invariant (21%) by profiling acr

57 Coexpression in Arabidopsis (Arabidopsis thaliana) seeds

58 to compare differential expression and gene coexpression in bronchiolitis and emphysema.

59 In addition, coexpression in camelina seeds of CpuDGAT1 with a C. vis

60 on datasets supports evidence for PDI/RhoGDI coexpression in developmental/inflammatory contexts.

61 Agrobacterium tumefaciens-mediated transient coexpression in Nicotiana benthamiana of an MtVAMP721e-R

62 iform opsin expression across the retina and coexpression in single cones creates a mostly mixed chro

63 We submit that global gene coexpression is a rich, largely untapped resource for di

64 hen they were expressed alone but that their coexpression led to coordinated assembly of virus-like p

65 Detailed analyses of a coexpression module highly correlated with the basal end

66 Conserved gene coexpression modules (four modules totaling 8398 genes)

67 We identified two SZ associated gene coexpression modules (green and red), including 446 gene

68 ene coexpression network analysis identified coexpression modules associated with single or multiple

69 gene network analysis, we identified 17 gene coexpression modules associated with TS.

70 luding identification and dissection of gene coexpression modules associated with wood phenotypes, GA

71 Coexpression modules were calculated, each of which cont

72 Using publicly available data, a gene coexpression network (GCN) can be constructed and used f

73 Coexpression network analyses revealed 13 striatal and 5

74 Coexpression network analyses revealed that regulation o

75 s samples, while differential expression and coexpression network analyses revealed transcriptional p

76 , combining differential expression and gene coexpression network analyses, we provide a comprehensiv

77 both fold change cutoffs and a weighted gene coexpression network analysis (WGCNA) to investigate coe

78 Weighted gene coexpression network analysis constructed 64 gene networ

79 Aggregated coexpression network analysis identified candidate enzym

80 Gene coexpression network analysis identified coexpression mo

81 Weighted Gene Coexpression Network Analysis revealed four gene modules

82 oups on the single-gene level, weighted gene coexpression network analysis revealed two modules of co

83 Weighted coexpression network analysis revealed unique clusters o

84 search Program was analyzed by weighted gene coexpression network analysis to identify gene networks

85 principal components analysis, weighted gene coexpression network analysis, meta-analyses, gene enric

86 Applying weighted gene coexpression network analysis, we define a group of lncR

87 Using weighted gene coexpression network analysis, we identified a module of

88 with clinical phenotypes using weighted gene coexpression network analysis.

89 developing Mt-abi5 seeds, we created a gene coexpression network and revealed ABI5 as a regulator of

90 n, were concentrated in a module of the gene coexpression network associated with innate immunity, an

91 One approach is to construct a single coexpression network by combining multiple expression da

92 alidation in different cotton accessions and coexpression network construction helped to identify sev

93 In addition, the P2K1-associated coexpression network contains defense-related genes, inc

94 ived from a murine isogenic cell line with a coexpression network derived by integrating 560 human pa

95 itional plastid peptidases and to generate a coexpression network for 97 organellar peptidase baits (

96 B-cell homing and activation; (2) the immune coexpression network had a central core of B cell-relate

97 Community detection in the coexpression network identified 27 of the 55 transcripti

98 del for grasses, no expression atlas or gene coexpression network is available.

99 can also be used to find condition-dependent coexpression network modules.

100 Inference of a gene coexpression network of 12 candidate transcription facto

101 Comparison with a human cortical development coexpression network revealed that genes disrupted in Pt

102 This study demonstrates that a gene coexpression network together with transcriptional modul

103 ls for exploring the expression profiles and coexpression network.

104 Coexpression networks and gene regulatory networks (GRNs

105 n patterns in combination with weighted gene coexpression networks and generalized additive models to

106 which we construct a large collection of 134 coexpression networks based on expression datasets repor

107 k analysis reveals that these genes comprise coexpression networks for acute-phase response and pro-i

108 Recent studies of gene coexpression networks have indicated that, not only gene

109 explore and visualize multiplied modules in coexpression networks of eight plant species.

110 Coexpression networks predict important roles for five s

111 Some studies involved construction of coexpression networks, a popular technique used to ident

112 ht associations (modules) with each other in coexpression networks, facilitating their identification

113 , long non-coding RNA (lncRNA) profiling and coexpression networks; (ii) phenotype-oriented data orga

114 effects were eliminated by either BTP2 or by coexpression of a dominant negative Orai construct.

115 ptogenetic activation and calcium imaging by coexpression of a red-shifted opsin and a genetically en

116 Second, coexpression of a set of 62 known NR coregulators and th

117 Through the coexpression of a xylose dehydrogenase (CCxylB) and a xy

118 apacity to induce the UPR(MT), but also that coexpression of alphaS and ATFS-1-associated dysregulati

119 protoplasts revealed that ABA treatment and coexpression of an ABA signaling master effector, ABA-RE

120 odies were efficiently sulfated in planta on coexpression of an engineered human tyrosylprotein sulfo

121 Finally, coexpression of apically targeted type I and type II TGF

122 ulointerstitial coexpression analysis showed coexpression of APOL1 mRNA levels with a group of intrar

123 Cellular coexpression of AT1A and LEPR was almost exclusive to th

124 There was, in fact, no requirement for coexpression of B7 and CD40 on the same cell in these re

125 FE1 through changes in iron metabolism while coexpression of both ADHFE1 and MYC strongly enhanced or

126 strategies, it is vital to learn more about coexpression of both inhibitory and stimulatory immune c

127 Coexpression of both proteins altered pUL31 localization

128 ression in KRAS-driven cancer cells, whereas coexpression of both proteins was critical to rescue miR

129 We therefore propose that coexpression of CD160 and 2B4 delineates a population of

130 proliferation but rather on antigen-induced coexpression of CD25 and OX40 (CD134).

131 malignant lymphoma cells, identified by the coexpression of CD4 and TOX (thymus high-mobility group

132 Based on the coexpression of CD69 and CXCR6, we identified a third ma

133 Furthermore, coexpression of CFTR stimulated SLC26A6-mediated Cl(-)-o

134 vitro and remyelination in vivo Furthermore, coexpression of cGSN and LINGO-1 blocked the inhibitory

135 cleus, and motor trigeminal nucleus; protein coexpression of CLR and RAMP1 was observed in these area

136 of SOX2, COX2, and YAP1 were observed, with coexpression of COX2 and YAP1 particularly commonly obse

137 CD27, ICOS), and had high levels of PD-1 and coexpression of CTLA-4.

138 Indeed, coexpression of Cul3WT and Cul3Delta9 in HEK293T(Cul3KO)

139 ion, nearly double the amounts obtained from coexpression of CvFatB1 and CvLPAT2 alone.

140 sp. PCC 6803, but also of ycf54; conversely, coexpression of cyanobacterial cycI and ycf54 is require

141 ranscriptional repressor of DCC and detected coexpression of DCC and miR-218 in pyramidal neurons of

142 t L1 retrotransposition may be influenced by coexpression of defective L1 loci and that these L1 loci

143 In a mouse model, brain-specific coexpression of DNAJB6 delays polyQ aggregation, relieve

144 Coexpression of DSP, occludin and FAK was detected in de

145 epithelium and Brunner glands with glandular coexpression of ErbB2, which is normally restricted to t

146 Ectopic coexpression of ERBB4 and COL29A1 genes was detected in

147 er, syncytia formation was much greater with coexpression of F, G, and TM.

148 uce the metabolic burden associated with the coexpression of F1 and LcrV within the live vector, we b

149 d levels of IFN-gamma only in the context of coexpression of FGR.

150 Strikingly, coexpression of FLAP in A23187-activated HEK293 cells ef

151 Coexpression of FLAP partially restored LTA4 hydrolysis

152 a finches and compared regional and cellular coexpression of FoxP1, FoxP2, and FoxP4 mRNA and protein

153 Most strikingly, coexpression of full-length, wild-type LDB1 increased LM

154 Coexpression of Gbetagamma-specific scavengers-namely, t

155 analysis of isolated Ptch2(+) cells revealed coexpression of genes characteristic of stromal progenit

156 sion network analysis (WGCNA) to investigate coexpression of genes, we found that the radial swelling

157 f light in the all-optical approach requires coexpression of genetically encoded activity sensors and

158 using functional cell-based assays involving coexpression of GIT1 and PAK3 (p21 protein (Cdc42/Rac)-a

159 In selected cases of FA, we analyzed the coexpression of HLA-DR, CD40, and CD80 in lung and LN eo

160 Recently, we have shown that coexpression of hMet and mutant-beta-catenin using sleep

161 We further demonstrated that coexpression of homogentisate geranylgeranyl transferase

162 Moreover, by the transient coexpression of human alpha2,8-polysialyltransferases, p

163 either human apo(a) only or human Lp(a) (via coexpression of human apo(a) and human apolipoprotein B)

164 D4(+) and CD8(+) T cell effectors defined by coexpression of IFN-gamma, IL-2, and CD107a after vaccin

165 Frequencies and coexpression of IFN-gamma, TNF-alpha, IL-2, IL-17, and/o

166 Coexpression of importin-alpha and inhibition of nuclear

167 terminal effector T cells, a decrease in the coexpression of inhibitory receptors, an improved Ag-spe

168 erized by impaired cytokine production, high coexpression of inhibitory receptors, and advanced cellu

169 Moreover, coexpression of JSRV Env and Zfp111 led to the identific

170 Our results indicate that coexpression of LAG-3 and 4-1BB characterize dysfunction

171 Coexpression of ligand and receptor by tumor cells (axis

172 egs) adopt specialized phenotypes defined by coexpression of lineage-defining transcription factors,

173 Coexpression of LLO and PlcA in a PrfA-negative strain w

174 ts, but an association can be bridged by the coexpression of M1.IMPORTANCE The complement of influenz

175 ture in human macrophages and illustrate the coexpression of MAFB and MAFB-target genes in CD163(+) t

176 n patients at an advanced stage, whereas the coexpression of markers that perform three and four func

177 Coexpression of MCPyV tLT did not appreciably alter the

178 espectively, while immunofluorescence showed coexpression of MMP-20 and DSPP.

179 Also, coexpression of Mp1, but not Mp1-like variants, specific

180 rowth and cell morphology were attenuated by coexpression of MPK6 in a phosphosite-dependent manner.

181 appears to have a dual AA phenotype based on coexpression of mRNA for the vesicular glutamate transpo

182 nal and phenotypic characterization revealed coexpression of multiple additional co-stimulatory and c

183 was less differentiated and associated with coexpression of multiple inhibitory receptors.

184 ressed with Ggamma2; this was in contrast to coexpression of mutant Gbeta2-Ggamma2 with other cardiac

185 Coexpression of mutant NRAS and EIF1AX proteins promoted

186 creased LMO2 steady-state abundance, whereas coexpression of mutant proteins deficient in LMO2 bindin

187 and characteristic immunohistochemistry with coexpression of myoid and melanocytic markers (HMB-45 /o

188 Coexpression of NaStEP and NaSIPP in pollen tubes showed

189 Coexpression of nephrin-CD16 and SHP-1 reduced nephrin t

190 Elevated coexpression of NOS2/COX2 proteins is a strong predictor

191 Coexpression of Nur77GFP and OX40 identifies a polyclona

192 Coexpression of OsONS1 with the two OsSQEs suggests that

193 d NP at the site of budding depends upon the coexpression of other viral proteins.

194 Coexpression of P plus M plus F, but not P plus M, M plu

195 py and subcellular fractionation showed that coexpression of P-Rex1 and Norbin induces a robust trans

196 Coexpression of p22/p18 and Ty1 decreases mobility more

197 There was minimal coexpression of p75NTR with ATF3, a marker for cell stre

198 Coexpression of patient-derived GNB1 variants with these

199 Taken together, these results indicate that coexpression of PD-1 and LAG-3 on T cells contributes to

200 erapy and could be identified by a sustained coexpression of PD-1 and TIGIT receptors.

201 Coexpression of PD-1 and Tim-3 above the median conferre

202 Here we assessed coexpression of PD-1, Lag-3, CD160, and 2B4 as a measure

203 -1 and HDAC4 inhibition was dependent on the coexpression of proapoptotic protein BAD.

204 y different from networks that were based on coexpression of proteins.

205 Simultaneous coexpression of proviral cellular factors with WW-domain

206 ndent manner and is also counteracted by the coexpression of PrP-WT.

207 phenotype that can also be eliminated by the coexpression of PrP-WT.

208 Finally, coexpression of Shaw(OX) and NKCC(RNAi) in a qsm mutant

209 Coexpression of sigmaNS and muNS resulted in disruption

210 First, we observed significant coexpression of six nuclear receptors (NRs) [androgen re

211 In particular, we observed coexpression of SOM with CR and CB.

212 Contrary to expectation, however, coexpression of SRK and SCR was found to inhibit SRK-med

213 sgenic mice, we show that epidermis-targeted coexpression of sT and the cell fate-determinant atonal

214 In contrast, coexpression of stabilized beta-catenin and PIK3CA(H1047

215 notypes, consistent with those of podocytes (coexpression of synaptopodin and Wilms tumor protein), p

216 Coexpression of T122K with wildtype AGA results in proce

217 Coexpression of TaGT43-4, TaGT47-13, TaGT75-3, and TaGT7

218 Upon coexpression of tandem PIP2-PIP1 dimers in Xenopus oocyt

219 tic cells (sDCs) to describe transcriptional coexpression of targets associated with a type 2 immune

220 Noggin, but not Tbx3, induces Pax6 and coexpression of Tbx3 and Pax6 is sufficient to determine

221 Transient coexpression of TcADH2 and TcALDH1 together with TcCDS i

222 h could instead be sensitively identified by coexpression of TCR-dependent activation markers.

223 nsporter 2 (VMAT2) mRNA, and there is little coexpression of TH and VMAT2 protein in this mesohabenul

224 dendritic cells, induce prominent and stable coexpression of TH1 and follicular helper T (TFH) cell c

225 Coexpression of the alpha-Syn(A30P) mutant with Munc18-1

226 interference (CRISPRi) system, we show that coexpression of the catalytically inactive Cas9 (dCas9)

227 In the human hepatoma cell line Huh7, the coexpression of the coactivators peroxisome proliferator

228 t in lower numbers than those observed after coexpression of the corresponding glycoproteins of a cli

229 Coexpression of the epithelial marker thyroid transcript

230 Coexpression of the full-length HBc rescued NTD assembly

231 D4+ T cell population critically depended on coexpression of the IL-23 receptor, which was required f

232 Remarkably, upon coexpression of the internalizing GLP-1R and the non-int

233 Coexpression of the mutants with wild-type Cx43 showed a

234 Furthermore, activity is not rescued by coexpression of the N-terminal fragment (TLR9(1-440)), i

235 can be released from retention in the TGN by coexpression of the plasma membrane-associated scaffold

236 es and the skin, and are identified by their coexpression of the TCR variable regions gamma4 and delt

237 Coexpression of the two receptors in BE(2)-C neuroblasto

238 Furthermore, coexpression of the viral reticulon-like transmembrane p

239 quantitative trait loci (eQTL) analyses, and coexpression of their host genes and regulatory miRNAs i

240 the generation of recombinant complexes via coexpression of their subunits from multigene DNA constr

241 Coexpression of these genes in 8 cells led to the elimin

242 Moreover, coexpression of these receptors continued to increase ev

243 ls mediate tolerance to tumor antigens, with coexpression of these receptors exacerbating this dysfun

244 5), which metabolizes D-2HG, and showed that coexpression of this enzyme with mutant Idh abolishes mu

245 e transcriptional phenotype characterized by coexpression of Treg and Th1 lineage genes and a downreg

246 Here, we demonstrate that heterologous coexpression of TREK-1 and TREK-2 subunits results in th

247 hRNAs for proof of concept, we validate that coexpression of TuDs can sequester and inactivate shRNA

248 Generating bispecific IgG by coexpression of two different light and heavy chains in

249 By coexpression of two differently tagged CAR proteins in H

250 The absence of coexpression of tyrosine hydroxylase, a marker for dopam

251 Coexpression of VfDGAT2 increased ESA levels to approxim

252 However, coexpression of wild-type caveolin-1 with mutated caveol

253 Coexpression of wild-type TRPC6 and TRPC6 G757D, mimicki

254 lted in inhibition of eVP40 VLP egress, (ii) coexpression of WWP1 and eVP40 resulted in ubiquitinatio

255 Interestingly, elevated coexpression on B cells coincided with an autoreactive T

256 indings by investigating the impact of their coexpression on breast cancer survival.

257 The baseline level of both CD39 and CD73 coexpression on regulatory T cells and ADO levels were h

258 ay that detects induction of CD25(+)CD134(+) coexpression on TB antigen-stimulated T cells from perip

259 RNF138-H36E coexpression only partially restores the dominant-negati

260 th and pathogen infection but have different coexpression partners.

261 ateralized in the spinal cord, interregional coexpression patterns are side specific, and intraregion

262 had little effect on frequencies or cytokine coexpression patterns of M. tuberculosis- or BCG-specifi

263 ta to prioritize candidate BGCs based on the coexpression patterns of predicted biosynthetic enzyme-c

264 ed connectivity within modules and exhibited coexpression patterns with other genes, including noncod

265 overlapping network modules show significant coexpression patterns, symptom similarity, and comorbidi

266 ing feature of this system is its asymmetric coexpression patterns, which suggest side-specific regul

267 conservation, regulator expression, and gene coexpression patterns, with the aim of dissecting the re

268 atterns are side specific, and intraregional coexpression profiles are affected differently by left-

269 Importantly, the gene coexpression profiles from human HCT recipients who deve

270 ned by lineage-defining transcription factor coexpression profiles that is disrupted by HIV infection

271 orter complexes in vitro and in vivo KCNQ2/3 coexpression protected SMIT1 activity from the otherwise

272 nse to DNA damage activation, LMP1 and LMP2A coexpression reduced gammaH2AX (S139) phosphorylation an

273 These coexpression relationships were also present in distinct

274 dSCCRO3 functioned cooperatively, with their coexpression resulting in an increase in both the neddyl

275 nation of HER2 and NF-kappaB receptor (RANK) coexpression revealed increased levels of both proteins

276 A coexpression search for MUCILAGE-RELATED (MUCI) genes id

277 expression together with SUF4, we performed coexpression studies that led to the identification of M

278 In this study, LMP1-2A coexpression suppressed activation of the DNA damage res

279 hat were frequently involved in differential coexpression tend to be related to plant immune response

280 Furthermore, coexpression the nonhomologous end-joining (NHEJ) machin

281 iption under conditions of ER stress or ATF4 coexpression: the -267 ATF/cAMP response element (CRE) s

282 t neuropeptide family, and by characterizing coexpression (transcriptionally coordinated) patterns of

283 The high coexpression values between SbMyb60 and genes assigned t

284 However, SbMyb60 showed low coexpression values with these genes and is not likely t

285 Overall, we found that differential coexpression was a common phenomenon of plant immunity.

286 Coexpression was further used both as a data-mining tool

287 of the high structural similarity and tissue coexpression, we here investigated the potential cross-t

288 Finally, by analyzing patterns of coexpression, we were able to propose potential biologic

289 of minimally functional ERV-1, and inversed coexpression when compared to neutrophils from type 2 di

290 iated with a decrease in inhibitory receptor coexpression, which could serve as biomarkers for monito

291 MOR translocates to the plasma membrane upon coexpression with beta2-adrenergic receptors (beta2-ARs)

292 immunoreactivity for MMP-20 in 18 (86%) and coexpression with DSPP in all 15 cases (71%) positive fo

293 peptides, showed the strongest differential coexpression with FGF1 between hypertensive and normoten

294 ates triacylglycerol accumulation, but their coexpression with KIN10 abrogates this effect by inducin

295 al cord and DRG cellular markers, as well as coexpression with mu-opioid receptors in DRG and brain r

296 ichiometry was unchanged by store depletion, coexpression with STIM1, or an Orai1 mutation (L273D) af

297 y metabolism, all had distinct signatures of coexpression with strong predictive value for assigning

298 truncated mutant (R316X) could be rescued by coexpression with the lacking C-terminal domain.

299 ues and treatments, along with its levels of coexpression with the majority of genes in the monoligno

300 essed in rats by examining the degree of NPY coexpression within interneurons or catecholaminergic fi