ライフサイエンスコーパス: cognate

1 Heat-shock cognate 70 (HSC-70) and tropomyosin showed IgE reactivit

2 ith tau and heat shock protein 90/heat shock cognate 70 (Hsp90/Hsc70) complexes.

3 y acid synthase (FAS), filamin-A, heat shock cognate 70-kDa protein, and OGT were confirmed by co-imm

4 onjugation, UFM1 undergoes activation by its cognate activating enzyme, UBA5.

5 adation by the PDZ-protease Prc bound to its cognate adaptor protein.

6 shown previously that when a BCR engages its cognate Ag on a cell surface that also expresses Siglec

7 should abolish B cell activation toward its cognate Ag on the surface of RBCs.

8 mory markers despite lack of engagement with cognate Ag); however, little is known about their traffi

9 idity can sense and respond to low levels of cognate Ag, a characteristic that is associated with mor

10 In contrast, cognate Ag-triggered proliferation was much less affecte

11 ng mice with Ag-specific Abs followed by the cognate Ag.

12 synthetases (aaRSs) charge tRNAs with their cognate amino acid, an essential precursor step to loadi

13 co-crystallization in the presence of their cognate amino acid, ATP, and/or inhibitors.

14 rving the bacterium Escherichia coli for the cognate amino acid.

15 ectively hydrolyse incorrectly activated non-cognate amino acids and/or misaminoacylated tRNAs.

16 quality control checkpoints that exclude non-cognate amino acids during translation, and in so doing

17 ), which not only catalyse the attachment of cognate amino acids to their respective tRNAs, but also

18 ylation of tRNA with commonly occurring near-cognate amino acids, their role has yet to be described

19 amino acids, bearing the side chains of the cognate amino acids.

20 NA sequence context plays a key role in near-cognate aminoacyl-tRNA selection during PTC suppression.

21 f mPyTK along with the identification of its cognate aminoacyl-tRNA synthetase makes it possible to m

22 on is mediated by the base pairing of a near-cognate aminoacyl-tRNA with a PTC and subsequently, the

23 ensembles of ribosomes with cognate or near-cognate aminoacyl-tRNAs delivered by EF-Tu.

24 Ribosomes decode mRNA codons by selecting cognate aminoacyl-tRNAs delivered by elongation factor T

25 ary experimental characterization of over 30 cognate and hybrid glutamine amidotransferase complexes

26 Both cognate and near-cognate tRNA anticodons explore the ami

27 differences between the pre-accommodation of cognate and near-cognate tRNAs that elucidate the mechan

28 nd we generated a representative ensemble of cognate and non-cognate complexes.

29 ive antibody-antigen interaction pairs among cognate and non-cognate complexes.

30 y allowing protease to differentiate between cognate and noncognate substrates.

31 larly, among the proteins purified, the SigT cognate anti-sigma factor RstA ranked the top with the m

32 l envelope antigens, host CD4 receptors, and cognate antibodies.

33 lowers the discrimination accuracy with the cognate antibody-antigen pair ranking in bound and unbou

34 soned that the ability of B cells to capture cognate antigen from cell membranes, along with small qu

35 The cognate antigen of a mouse monoclonal antibody raised ag

36 played a higher functional avidity for their cognate antigen than Vss subfamilies not amplified upon

37 r cytokines, proliferate less in response to cognate antigen, and upregulate cell surface inhibitory

38 lts in increased production of antibodies to cognate antigen.

39 l pool that expand upon reencounter of their cognate antigen.

40 the surprising specificity of TCRs for their cognate antigens and enables the facile indentification

41 Neutrophils pulsed with the cognate antigens cytomegalovirus pp65 or influenza hemag

42 e enriched within scaffolds containing their cognate antigens.

43 checkpoint molecule to enforce tolerance to cognate antigens.

44 es would be determined by their affinity for cognate antigens.

45 rom 10-fold to over 900-fold, in response to cognate antisense RNAs.

46 st folding and to prevent degradation of its cognate antitoxin, thus facilitating inhibition of the t

47 ne response by enhancement of T cell help to cognate B cells.

48 id TLR9-sufficient mice, suggesting that the cognate BCR efficiently internalizes the Id in an IC wit

49 ble of recruiting endogenous copies of their cognate binding partners to targeted genomic binding sit

50 ulti-specific ligand and the affinity of its cognate binding site.

51 cis sequence motifs enriched in the PREs are cognate binding sites for the identified transcription f

52 ffectively lowering MYC/MAX occupancy at its cognate binding sites.

53 also overrepresented among targets, but the cognate BSs and the identity of the regulated genes were

54 biologic functions through activation of its cognate C3a receptor.

55 e a similar qRT-PCR detection ratio as their cognate canonical miRNAs.

56 the notion that catalytic modules and their cognate CBMs have complementary specificities, including

57 TNF plus doxorubicin treatment, arguing that cognate CD8(+) T cells contributed to tumor eradication.

58 nity proteins, which specifically neutralize cognate CdiA-CT toxins to prevent self-inhibition.

59 n and bovine TLR5 activity and signalling in cognate cell lines.

60 rks were enriched in disease-causing SNPs of cognate cell types.

61 rystal structures of affimers bound to their cognate chain types reveal mechanisms of specificity and

62 activation was induced by co-expression of a cognate channel, AQP1.

63 ic; meaning that only cells that express the cognate chemokine cell surface receptor, migrate under t

64 Cells expressing the corresponding cognate chemokine receptors migrate against this gradien

65 Previous studies have implicated a cognate cis interaction between the bent conformation be

66 group has a lower affinity of binding to the cognate codon and is more efficiently rejected than the

67 s exceeded the highest reported rates of non-cognate codon recognition.

68 coding-centre nucleotide G530 stabilizes the cognate codon-anticodon helix, initiating step-wise 'lat

69 , the correspondence between amino acids and cognate codons was determined by recognition of amino ac

70 configuration that permits pairing of a near-cognate complex at a PTC.

71 By contrast, near-cognate complexes fail to induce the G530 latch, thus fa

72 nd models but recovers additional top-ranked cognate complexes when using homology models.

73 a representative ensemble of cognate and non-cognate complexes.

74 igen interaction pairs among cognate and non-cognate complexes.

75 finity and catalytic efficiency toward their cognate CPs in comparison with noncognate substrates.

76 tion upon high-affinity interaction with the cognate CTLR keratinocyte-associated C-type lectin (KACL

77 ecognition of the AUG codon but not the near-cognate CUG codon regardless of its nucleotide context d

78 Here we investigate the role of CycC, the cognate cyclin partner of Cdk8, in cell cycle control.

79 dels (HMMs) and is available together with a cognate database that may be used for specific analyses.

80 can induce apoptosis in cells expressing its cognate death receptors (DRs).

81 A4 by rapidly hydrolyzing 14,15-EET into its cognate diol, eliminating a proresolving signal that pot

82 bly, the consensus-HD binds the engrailed-HD cognate DNA in a similar mode as the engrailed-HD with a

83 rved binding of human PRDM9 alleles to their cognate DNA sequences.

84 stems generate displacement (R-loops) in the cognate DNA sites, targeting the transposon to these sit

85 he C-terminal ZBTB38 ZFs in complex with its cognate DNA target is proposed, providing insight into a

86 factor, activator protein-1 (AP-1), binds to cognate DNA under redox control; yet, the underlying mec

87 a are bound as repressing complexes to their cognate DNA-binding sequence(s) (DBS) in the TSLP promot

88 phosphorylation impedes ITCH binding to its cognate E2 ubiquitin ligase, UbcH7.

89 molecular basis for the specificity of this cognate E2/RBR E3 pair.

90 gers subsequent downstream transfer to their cognate E2s resulting in the fidelity of the Ub/UBL conj

91 ed primary and secondary structure and their cognate effector molecule.

92 s that contain unique Rab proteins and their cognate effectors, which drive all steps of membrane tra

93 , each dedicated to mediate the secretion of cognate effectors.

94 protein-coupled receptors (GPCRs) with their cognate endogenous ligands is expected to have a major i

95 consisting of TcsA, TcrA, FsrR, RpoN and its cognate enhancer-binding protein EbpA, which is required

96 al-oxo complexes has been documented, but no cognate enzymatic process is known.

97 upon binding the extracellular domain of the cognate EphB2 receptor.

98 n partners with cells ectopically expressing cognate, 'flipped' t-SNAREs.

99 anergic phenotype that interferes with their cognate function against Klebsiella pneumoniae and Esche

100 transients like those recorded with another cognate G protein-coupled muscarinic receptor, M1R.

101 porum alpha-pheromone was independent of the cognate G protein-coupled receptors Ste2 and of the cent

102 E-series resolvin (RvE) 1, and activation of cognate G protein-coupled receptors.

103 the interaction of small peptides with their cognate G protein-coupled receptors.

104 e to identify small molecule agonists of the cognate G-protein coupled receptor for H2-RLX (relaxin f

105 Despite being unable to activate the cognate ghrelin receptor (GHS-R), unacylated ghrelin (UA

106 Moreover, DTD's activity on non-cognate Gly-tRNA(Ala) is conserved across all bacteria a

107 e associates between Gi/o proteins and their cognate GPCRs in the inactive state (Gi/o-GPCR preassemb

108 pathways are established by their specific, cognate guanine nucleotide exchange factors (GEFs) and G

109 e canonical start codon (AUG) and a few near-cognates (GUG, UUG) are considered as the 'start codons'

110 n of signaling pathways downstream CD44, the cognate HA receptor, in nociceptors.

111 estigation is the potential randomization of cognate heavy (H) chain/light (L) chain pairing, which c

112 hed mice represent an unprecedented model of cognate hFcgammaR expression.

113 ction of long single-stranded (ss) RNAs with cognate homologous double-stranded (ds) DNA in vitro Usi

114 iated by viral glycoproteins upon binding to cognate host receptors or entering into acidic intracell

115 in male Sprague Dawley rats, the role of the cognate hyaluronan receptor, CD44 signaling in the antih

116 ng affinity of Igs that already exist (i.e., cognate Igs) because of chance generation during preimmu

117 Regulation of TNFAIP3/A20 expression and cognate IL-17A production in T cells are specifically me

118 and VEGF in the peritoneum, do not bear the cognate IL-6 receptor and are thus unable to respond to

119 perties that produce contrast signal for the cognate imaging modality-we stratify nanomaterials on th

120 ectors are neutralized by adjacently encoded cognate immunity determinants.

121 dult microbiomes harbor limited effector and cognate immunity genes, suggesting selection for compati

122 eplaces ancestral effectors, yet retains the cognate immunity genes.

123 ichia coli NC101 in ternary complex with its cognate immunity protein and elongation factor Tu (EF-Tu

124 rowth inhibition of sister cells lacking the cognate immunity protein.

125 nes constructed with inducible promoters and cognate-inducible short hairpin RNA (shRNA) targeted aga

126 high amounts of dopamine and release it upon cognate interaction with B cells.

127 sented IL-6 to T cells during the process of cognate interaction.

128 Cognate interactions between T follicular helper (Tfh) c

129 the production of IL-6 by APC during initial cognate interactions in the generation of effective CD4

130 modulation of second messenger signaling for cognate interactions.

131 e conformer of benenodin-1 is cleaved by its cognate isopeptidase.

132 ng a regulatory mechanism requiring the OmpR cognate kinase EnvZ, but not OmpR phosphorylation.

133 vident that many orphan regulators that lack cognate kinases do not rely on phosphorylation for activ

134 serine/threonine-proline sequences by their cognate kinases.

135 widely varying academic specializations with cognate knowledge of disease and epidemics that seems to

136 ell-surface expression in the absence of the cognate Kunitz-type serine protease inhibitors, hepatocy

137 would introduce biologic noise compromising cognate ligand detection.

138 logic noise filter to enhance reliability of cognate ligand detection.

139 g subtypes of the ubiquitous KIR3DL1 and its cognate ligand, HLA-B, would titrate NK reactivity again

140 The human Y4 receptor (Y4R) and its cognate ligand, pancreatic polypeptide (PP), are involve

141 We argue that LFA-1 contact with a cognate ligand, such as ICAM-1, independent of the immun

142 , conserved specific triggers encoded in the cognate ligands activate a promiscuous binding pathway t

143 hogen recognition receptors (PRRs) via their cognate ligands are critical for enhancing antigen-prese

144 ripto-1 and Cryptic blocked binding of their cognate ligands to type I and type II TGF-beta receptors

145 R4, frequently referred to as GPR48) and its cognate ligands, R-spondins (RSPOs) play crucial roles i

146 hat makes Eph receptors unique is that their cognate ligands, the ephrins, are tethered to the cell s

147 regulation of effector protein activities by cognate metaeffectors as being critical for host pathoge

148 We found that cognate metal binding altered flexibility from the N ter

149 Our results suggest that cognate metal binding to RcnR orders its N terminus, dec

150 inus and His-3, and has been associated with cognate metal binding.

151 e RcnR structure in the presence of DNA, the cognate metal ions Ni(II) and Co(II), or the noncognate

152 espond at the lowest concentrations of their cognate metal, explaining specificity.

153 However, in vitro all these sensors bind non-cognate metals, which alters DNA binding.

154 ence-specific transcription factors (TFs) to cognate motifs.

155 eal that an interdependence of a protein and cognate mRNA maintains asymmetric protein distribution i

156 ion defects caused by mislocalization of the cognate mRNA were rescued by introducing untagged mRNA c

157 c localization requires interaction with the cognate mRNA.

158 ed that these differential responses involve cognate MyD88 recognition.

159 rystal structure of MLC1 in complex with its cognate MyoA peptide.

160 While a cognate N domain is not required for crescent formation,

161 We introduce a new concept that utilizes cognate nucleic acid nanoparticles which are fully compl

162 FisR binds to its cognate operator at -114 to -135 bp of the transcription

163 ution structural ensembles of ribosomes with cognate or near-cognate aminoacyl-tRNAs delivered by EF-

164 on initiation: usage of AUG-like sites (near cognates) or repeat-associated non-AUG (RAN) translation

165 ivating polypeptide (PACAP; Adcyap1) and its cognate PAC1 receptor (Adcyap1r1) are expressed in perip

166 clase activating polypeptide (PACAP) and its cognate PAC1 receptor transcript, and BNST PACAP signali

167 Rosetta interface score as a classifier, the cognate pair was the top-ranked model in 80% (14/17) of

168 Here, we report that its cognate partner VAMP721, which assembles with SYP121 to

169 Binding is strongest between cognate partners in cidA-cidB homologues.

170 ve clones exhibited a level of activation by cognate peptide and inhibition of in vitro HIV-1 infecti

171 Following cognate peptide stimulation, effective HIV-specific clon

172 CD8 T cells in vitro to varying densities of cognate peptide-MHC ligand followed by ligand-free cultu

173 ) network and present the highest density of cognate peptides to follicular helper T (Tfh) cells, whi

174 brane serine/threonine kinase (IreK) and its cognate phosphatase (IreP) reciprocally regulate cephalo

175 naptic release apparatus is matched with its cognate postsynaptic machinery.

176 e of a sigma(N) fragment in complex with its cognate promoter DNA, revealing the molecular details of

177 This architectural change facilitates cognate promoter-enhancer contacts and also requires Myc

178 nce in the establishment of pausing at their cognate promoters.

179 Because adaptors must bind their cognate protease, all adaptors run the risk of being rec

180 ly bind cargo and tether substrates to their cognate proteases to promote substrate destruction, wher

181 rtially mediated through cellular heat shock cognate protein 70 (Hsc70).

182 re associated with distinct distributions of cognate protein kinases.

183 se-mediated activities by inactivating their cognate proteinases, and are involved in multiple physio

184 The cognate proteins are components of the florigenic signal

185 confined to the nucleus at prophase, and the cognate proteins are not translated until the redistribu

186 we produced transgenic (Tg) mice expressing cognate PrP(C) Although disease transmission to only a s

187 y regulated to reflect availability of their cognate PVD.

188 ) siderophore receptors in response to their cognate PVD.

189 rmation and explains the specificity of this cognate RBR E3/E2 pair.

190 that serine integrases can be fused to their cognate RDFs to create single proteins that catalyse eff

191 scription factor; also known as NRSF) to its cognate RE1 sequences is temporally regulated by non-CpG

192 ere not evolutionarily tuned to prefer their cognate reactions.

193 etic and pharmacological targeting of apelin cognate receptor abrogates apelin- and endothelial-media

194 gulates peripheral nerve myelination via its cognate receptor ADAM22 expressed by neurons.

195 nt (Lasius niger), identified and cloned its cognate receptor and determined its pharmacological prop

196 d important cardiovascular risk factor whose cognate receptor and intracellular fate remains unknown.

197 n of mammary epithelial cells (MECs) via its cognate receptor and the downstream JAK2-STAT5a signalli

198 anistic paradigm for IL-23 and IL-12 whereby cognate receptor binding to the helical cytokine subunit

199 mbopoietin, which in turn interacts with its cognate receptor c-MPL on megakaryocytes and bone marrow

200 d affinity of the nitrated chemokine for its cognate receptor CCR2b.

201 er CD70 surface expression or binding to its cognate receptor CD27.

202 Moreover, perception of flg22 by its cognate receptor complex triggers actin remodeling throu

203 weight remain poorly understood, because the cognate receptor for GDF15 is unknown.

204 istinct gene family clades, as well as their cognate receptor genes.

205 ce to interact with both the aptamer and its cognate receptor IL-1RI, thereby suggesting a novel rout

206 2 in order to conformationally constrain the cognate receptor in an IL-1RAcP-receptive state.

207 peptide transferred to females [7], and its cognate receptor in the female, NPYLR1 [8], in rapid enf

208 binding protein (DBP) dimerization with its cognate receptor is vital for junction formation in the

209 We asked if leptin and its cognate receptor were present in normal and diseased par

210 (hIL-18) in complex with its antagonists or cognate receptor(s) have revealed a conserved binding in

211 otein interactions with both IL-18BP and its cognate receptor(s).

212 structure of human IL-23 in complex with its cognate receptor, IL-23R, and revealed that IL-23R bound

213 e report that the FLP-7 neuropeptide and its cognate receptor, NPR-22, function as the ligand-recepto

214 evaluated the contribution of Ox40L and its cognate receptor, Ox40, using in vivo agonist and antago

215 Its cognate receptor, required for its fusogenic activity, w

216 UF1 to its cognate receptor, SIGNR1, on dendritic cells resulted in

217 e a signaling complex that includes both its cognate receptor, ST2, and the shared co-receptor IL-1RA

218 effect was (i) shown to depend on one of its cognate receptor, TAS2R43, and adenylyl cyclase; and (ii

219 VEGF binding to its cognate receptor, VEGFR2, activates a number of signalin

220 owing to the absence of a clearly identified cognate receptor.

221 ed as a regulator of mIndy by binding to its cognate receptor.

222 s to iron because import requires a suitable cognate receptor.

223 priately position molecules to interact with cognate receptors and the ability of modified surfaces t

224 othelial cells in remodeling SpAs, and their cognate receptors are present in both dNK cells and macr

225 x (ECM) proteins and the expression of their cognate receptors dictate cell behavior and dynamics.

226 ytocin-like neuropeptide, nematocin, and its cognate receptors have been identified in the nematode C

227 However, expression of myostatin and its cognate receptors in other tissues, including brain and

228 Binding of chemokines to their cognate receptors on monocytes instigates a cascade of e

229 imeric structures (hexa-Fcs) that bind their cognate receptors with high avidity.

230 whereas the MM cells express the respective cognate receptors, supporting their role in directional

231 ands can block their interactions with their cognate receptors, they can also significantly increase

232 They function by binding their cognate receptors, which are transcription factors that

233 eted signaling molecules (ligands) and their cognate receptors.

234 y deliver multiple inhibitory ligands to the cognate receptors.

235 acellular matrix, and presents them to their cognate receptors.

236 Ligation of OX40 L and JAG1 with their cognate-receptors OX40 and Notch3, preferentially expres

237 a recognize these methyl groups within their cognate response elements.

238 se (HK) followed by phosphoryl transfer to a cognate response regulator (RR) protein, which may affec

239 PlrS most likely functions via the putative cognate response regulator PlrR.

240 d that it also forms cage complexes with the cognate riboflavin synthase (AaRS) when both proteins ar

241 U6 RNA dramatically alters its affinity for cognate RNA-binding proteins.

242 egree diverse TCR-mediated interactions with cognate self-antigens are required for these processes.

243 The response regulator PhoP and its cognate sensor kinase PhoQ compose a two-component syste

244 The cognate sensors are modelled to respond at the lowest co

245 scription factor from the Rgg family and its cognate SHP (short hydrophobic peptide).

246 ures revealed that each antibody engages its cognate sigma1 protein within the head domain via epitop

247 function SSAPs require the activity of their cognate single strand binding (Ssb) proteins.

248 Focusing on ATF3, we observed distinct cognate site preferences conferred by different bZIP par

249 fter unbinding, CTCF quickly rebinds another cognate site unlike cohesin for which the search process

250 (i) sequential G-protein interactions at the cognate site, (ii) G-protein interactions at distinct al

251 ed and green 'transcription factors' bind to cognate sites in strings of beads ('chromatin') to form

252 cing the binding of transcription factors to cognate sites in the genome, with consequent local acqui

253 tein interactions at distinct allosteric and cognate sites on the GPCR, and (iii) asymmetric GPCR dim

254 ecificity of transcription factors and their cognate sites.

255 Each sitA is associated with a cognate sitI immunity gene, and in some cases a sitB acc

256 y, we show that lipid-anchored STX11 and its cognate SNARE proteins mainly support exchange of lipids

257 ion by activating syntaxin-4 (STX-4) to bind cognate SNARE proteins to form a SNARE complex that medi

258 llusk egg coat protein, VERL, complexed with cognate sperm protein lysin.

259 oximity-dependent ligation and sequencing of cognate sRNA-mRNA pairs as chimeric reads.

260 yndrome is initiated at an upstream ACG near-cognate start codon.

261 hus exists that H2 [(CF3 )7 TpFPP]2 H2 O and cognate structures may act as supramolecular synthons, w

262 trikingly, FEN1 never misses cleavage of its cognate substrate while blocking probable formation of c

263 te that greatly stabilized proteins can bind cognate substrates with increased affinities, showing th

264 ion of RNA-destabilizing proteins with their cognate substrates.

265 pled to outer membrane passage through their cognate SusC transporter is unknown.

266 However, only 5 of the peptides induced cognate T cells in humans; these peptides exhibited stro

267 ualize how these nanomedicines interact with cognate T cells.

268 n receptor microclusters on murine and human cognate T cells.

269 tive activation of these enhancers and their cognate target genes, and it leads to the inhibition of

270 een shown to inhibit biological functions of cognate target proteins, and they are identifiable by an

271 change the stability or functionality of its cognate target proteins.

272 d and specific binding of molecules to their cognate targets.

273 Expression of TAS2Rs, including cognate TAS2Rs for caffeine, was shown in human gastric

274 -2 on B cells are essential for long-lasting cognate Tfh-B cell interactions and efficient selection

275 xpression profiles, and subsequently testing cognate TFRE activities in varying homotypic and heterot

276 utative subtype-specific enhancers and their cognate TFs by integrating the magnitude of enhancer tra

277 athway as a crucial element for induction of cognate Th1 responses against an important human pathoge

278 Up-regulation of the tRNA cognate to the mutated codon counteracts the effects of

279 (mRNA) and an uncharged transfer RNA (tRNA) cognate to the terminal mRNA codon bound to the 70S ribo

280 s of antitoxin proteins which releases their cognate toxin partners causing rapid inhibition of growt

281 in concentrations and the activity of CcdA's cognate toxin.

282 mining how cis-regulatory elements and their cognate transcription factors are organized in genetic r

283 hmC was correlated with up-regulation of the cognate transcripts, including many oncogenic pathways i

284 Both cognate and near-cognate tRNA anticodons explore the aminoacyl-tRNA-bindi

285 are responsible for charging amino acids to cognate tRNA molecules, which is the essential first ste

286 It has an aptamer domain for cognate tRNA recognition and an expression platform to s

287 i-terminated glyQS T-box in complex with its cognate tRNAGly was derived based on the molecular envel

288 en the pre-accommodation of cognate and near-cognate tRNAs that elucidate the mechanism of accurate d

289 irst to show that BDNF signaling through the cognate tropomyosin receptor kinase type B (trkB) recept

290 We hypothesized that disrupting the cognate type I IFN receptor (type I IFN alpha/beta recep

291 city via an editing pathway that targets non-cognate Tyr-tRNAPhe.

292 h a reduced efficiency of termination on the cognate UAA codon.

293 wo different unnatural codons and tRNAs with cognate unnatural anticodons, and their efficient decodi

294 in yeast eIF1A suppresses initiation at near-cognate UUG codons and AUGs in poor context.

295 n initiation and diminish initiation at near-cognate UUG start codons in yeast mutants in which UUG s

296 al activation of several transgenes carrying cognate variable activating sequences (VAS) in distinct

297 sting that interactions of the N domain with cognate viral proteins may be critical for virion assemb

298 that one of its two domains cooperates with cognate viral proteins.

299 n a manner that correlated between cells and cognate virions (P = 0.027).

300 based on a critical density threshold of its cognate VSGs on the parasite surface.