ライフサイエンスコーパス: cognitive

1 out artifacts by demonstrating that distinct cognitive abilities are genetically correlated and thus

2 nship between general intelligence and socio-cognitive abilities is poorly understood in animals and

3 they make unrealistic assumptions about the cognitive abilities of bat pollinators, invoke Weber's l

4 oximately 3 y of age, we assessed children's cognitive abilities with the Wechsler Primary and Presch

5 link between general intelligence and socio-cognitive abilities within humans.

6 Honeybees have remarkable visual cognitive abilities, allowing them to classify visual pa

7 on and is a precursor for a variety of socio-cognitive abilities.

8 .e., inhibitory control) are essential human cognitive abilities.

9 ividuals of different species using the same cognitive ability battery.

10 ype I interferon in aged mouse brain impedes cognitive ability by altering microglia transcriptome an

11 ation between low birth weight and decreased cognitive ability has declined between the 1950s and 197

12 These results suggest that cognitive abnormalities in disorders like schizophrenia

13 FIGSKO mice also develop cognitive abnormalities, i.e. learning impairment and ne

14 easure of cerebral blood flow in response to cognitive activity.

15 nition (Alzheimer's Disease Assessment Scale-cognitive [ADAS-Cog]) and self-reported QoL (Quality of

16 ely to explain previously observed bilingual cognitive advantages across the lifespan.

17 n primates, and humans that demonstrates how cognitive aging affects the navigational computations su

18 Ptchd1 knock-out (KO) male mice exhibit cognitive alterations, including defects in a novel obje

19 ) inflammation with long-term behavioral and cognitive alterations.

20 s followed by a comprehensive behavioral and cognitive analysis.

21 lopmental condition associated with impaired cognitive and adaptive behaviors.

22 childhood, and this significantly influences cognitive and behavioral development in later life.

23 al role in establishing complex and adaptive cognitive and behavioral processing.

24 function is believed to underlie many of the cognitive and behavioural phenotypes associated with fra

25 Cognitive and behavioural scores correlated with diffusi

26 ould be investigated as a means of improving cognitive and depressive outcomes in well-designed studi

27 ing from complete motor paralysis but intact cognitive and emotional processing, a state called compl

28 comparison and interrelations between global cognitive and fluency performance, lesion topography, an

29 f brain aging in later life, contributing to cognitive and memory decline, is unknown.

30 rative disorder that results in debilitating cognitive and motor dysfunction.

31 In rural Bangladesh we examined cognitive and motor function and scholastic achievement

32 changes in thalamic development, and thereby cognitive and motor function.

33 frontopolar cortex (FPC) plays in motivating cognitive and physical effort exertion by computing subj

34 Critically, reward devaluation by both cognitive and physical effort was subserved by a common

35 tures including demographic characteristics, cognitive and physical traits and lifestyle choices.

36 der, and the presence of chronic conditions, cognitive and social activity, physical activity, health

37 output is causally correlated with both the cognitive and the sensory component of neuropathic pain.

38 Longitudinal motor, cognitive, and imaging scores were correlated with each

39 Studying physical, cognitive, and social health might further clarify the p

40 entry point toward a better understanding of cognitive architectures.

41 iscrepancies between the groups, none of the cognitive assessment resulted in significant deficits.

42 mination and 27 of 30 points on the Montreal Cognitive Assessment) and normal cerebellar, sensory, cr

43 imaging ([18F]-florbetapir) at baseline and cognitive assessments at baseline and a 4-year follow-up

44 The value of cognitive assessments in psychiatric research can be sub

45 Improve Cognition in Schizophrenia Consensus Cognitive Battery (MCCB) in cognitive impairment associa

46 gnition in schizophrenia (MATRICS) consensus cognitive battery (MCCB), especially focusing on reasoni

47 The MATRICS Consensus Cognitive Battery was utilized to measure cognitive perf

48 Cognitive behavioral therapy reduced primary anxiety sym

49 moderator and index of symptom change during cognitive-behavioral therapy (CBT) or selective serotoni

50 othesised that brief guided parent-delivered cognitive behavioural therapy (CBT) would be associated

51 The association of cognitive benefit with DHA supplementation in predementi

52 ndependent domain-general strategy to master cognitive challenges.

53 to examine which demographic, clinical, and cognitive characteristics were associated with improveme

54 ve images without enhancing an ERP marker of cognitive control (i.e., stimulus preceding negativity).

55 ensatory neural mechanisms such as increased cognitive control and the suppression of task irrelevant

56 regulation, self-referential processing and cognitive control more strongly than women.

57 ity to recruit the dlPFC, which mediates the cognitive control needed to overcome anxiety and differe

58 k' (e.g., medial prefrontal cortex; mPFC), a cognitive control network [e.g., dorsolateral (dl)PFC],

59 gence has been associated with a distributed cognitive control or multiple-demand (MD) network, compr

60 matched healthy control participants during cognitive control tasks.

61 elaxation rate (R2) that was associated with cognitive decline after controlling for common neuropath

62 se and heart failure may contribute to early cognitive decline and (vascular) dementia.

63 re, surgery may accelerate the trajectory of cognitive decline and dementia.

64 out psychosis, AD+P subjects have more rapid cognitive decline and poor outcomes.

65 logical and psychiatric disorders, including cognitive decline associated with Alzheimer's disease or

66 ntifying individuals potentially at risk for cognitive decline associated with preclinical AD.SIGNIFI

67 allogeneic HCT recipients showed significant cognitive decline compared with healthy controls.

68 ng amyloid-beta-induced loss of synapses and cognitive decline in Alzheimer's disease mice.

69 stage of AD reduces brain atrophy, prevents cognitive decline in LMCI and delays conversion to AD de

70 Mild cognitive decline occurred in half.

71 FDG metabolism were predictive of subsequent cognitive decline rated with the MMSE and MoCA.

72 ive cognitive dysfunction and other forms of cognitive decline related to immune-to-brain communicati

73 nd social participation buffered the risk of cognitive decline resulting from housing damage.

74 economic marker) with cognitive performance, cognitive decline, and dementia (N dementia/total = 195/

75 synergistically with amyloidosis to produce cognitive decline, and drives amyloid-independent brain

76 disease (AD) is characterized by progressive cognitive decline, increasingly attributed to neuronal d

77 ts, the increased risk of adverse events and cognitive decline, there is an unmet need for well-toler

78 y outcome) and secondarily for postoperative cognitive decline.

79 at these supplements did not reduce risk for cognitive decline.

80 tributing to neurodegenerative processes and cognitive decline.

81 in and associates with immune activation and cognitive decline.

82 Abeta phagocytosis and the stabilization of cognitive decline.

83 MCI and dementia; global and domain-specific cognitive decline.

84 ded on baseline cognitive status (subjective cognitive decline: hazard ratio [HR] = 0.57, p < 0.05; m

85 mutations of PHF8 have been associated with cognitive defects and cleft lip/palate, its role in mamm

86 levels and spine plasticity and ameliorates cognitive defects in IL-1R8 KO mice.

87 hagy contributes to synaptic dysfunction and cognitive deficits by triggering Abeta and Tau accumulat

88 mation integration and organization and thus cognitive deficits in patients with PD.

89 re consistently and robustly associated with cognitive deficits of ASD and ID in humans, and overexpr

90 f nicotine and related agonists for treating cognitive deficits, these data suggest that daily dosing

91 unclear whether these changes are related to cognitive deficits, which have been described in ET pati

92 rse serum lipids, and smoking associate with cognitive deficits.

93 ment is an important factor underlying these cognitive deficits.

94 roduction, in turn leading to depression and cognitive deficits.

95 as a promising therapeutic approach to treat cognitive deficits.

96 Elderly adults may master challenging cognitive demands by additionally recruiting the cross-h

97 cantly slower rate of functional, motor, and cognitive deterioration (all p < 0.001), independent of

98 Whereas some contribute to progressive cognitive deterioration, others lower the level of cogni

99 luences is vital to advancing the science of cognitive development as well as for designing intervent

100 maternal sensory signals causally influences cognitive development.

101 ensitivity to numerosity is related to their cognitive development.

102 y oncology clinics report substantially more cognitive difficulties up to 6 months after treatment wi

103 read or write in English or Danish, or had a cognitive disability that would preclude their understan

104 decisions associated with a higher level of cognitive dissonance elicited a stronger negative fronto

105 d follow-up neural and behavioral effects of cognitive dissonance.

106 The present paper discusses 3 common cognitive distortions: 1) dichotomania, the compulsion t

107 hearing loss to impaired performance across cognitive domains and increased risk for dementia diagno

108 We used only one test to represent cognitive domains, and though a prototypical one, we nev

109 owing to different methods to assess SDB or cognitive domains, making it difficult to draw conclusio

110 Overall cognition, individual cognitive domains, psychosocial function, and activities

111 For component cognitive domains, the association with (pooled) SiN per

112 lain differential ageing trajectories across cognitive domains.

113 and ASSR as a translational end point in pro-cognitive drug discovery and early-phase clinical trials

114 ue to their potential role in post-operative cognitive dysfunction (POCD).

115 therapies to prevent or treat postoperative cognitive dysfunction and other forms of cognitive decli

116 of the most common genetic risk factors for cognitive dysfunction and schizophrenia, we found that g

117 n, neurodegeneration-associated changes, and cognitive dysfunction arising after sepsis recovery.

118 abnormal pattern of neural activity underlie cognitive dysfunction in PP-MS, and that CLs possibly pl

119 ety and probable behaviour disorder, but not cognitive dysfunction or motor severity.

120 tween androgen deprivation therapy (ADT) and cognitive dysfunction, including Alzheimer disease.

121 mong these precursors of type 2 diabetes and cognitive dysfunction.

122 iated with 44% (9-91%) larger probability of cognitive dysfunction.

123 attenuates or exacerbates the behavioral and cognitive effects of THC.

124 gical and physiological variables, including cognitive effort, arousal, attention, and even learning.

125 se fusion protein confirmed the link between cognitive enhancement and MEF2C occupancy at promoters h

126 As physicians age, a required cognitive evaluation combined with a confidential, anony

127 de surveys, ascribing reduced capacities for cognitive, experiential, and emotional states to victims

128 cillations, which support memory, attention, cognitive flexibility and sensory responses.

129 Verb and phonemic fluency, working memory, cognitive flexibility, immediate and delayed recall, ver

130 rological diseases characterized by declined cognitive flexibility.SIGNIFICANCE STATEMENT Activation

131 y (open field test, light-dark box test) and cognitive function (novel object recognition test).

132 althy participants aged 65 y and over in the Cognitive Function and Ageing Study Wales (CFAS-Wales) c

133 al balance of n-6 and n-3 FAs depends on the cognitive function and developmental period studied.

134 ) infection is associated with impairment of cognitive function and mood disorders.

135 genetically strongly associated with general cognitive function and processing speed.

136 cipants (N=18) were administered measures of cognitive function and questionnaires concerning psychos

137 ence in cognitive function z score) on child cognitive function at age 7-14 years (i.e., joint mediat

138 regions and circuits important in executive cognitive function can bias behavioral choices away from

139 Moreover, dissociating innate differences in cognitive function from cannabis-induced deficits is cha

140 ent revitalizes the hippocampus and improves cognitive function in aged mice.

141 ternal sensory signals early in life impacts cognitive function in both rats and humans.

142 sts that glycemic control is associated with cognitive function in older patients with type 2 diabete

143 ewborn supplementation with vitamin A on the cognitive function of children at 8 y of age.A cohort of

144 nically significant decline in self-reported cognitive function than were controls from prechemothera

145 INTERPRETATION: Decline in cognitive function was more frequent with WBRT than with

146 r associations with global or memory-related cognitive function were non-significant and in opposing

147 rs had a larger direct effect (difference in cognitive function z score) on child cognitive function

148 g cardiovascular disease, cancer, decline in cognitive function, and mortality.We investigated the as

149 mportant consideration in the role of FAs in cognitive function, and the optimal balance of n-6 and n

150 co withdrawal is associated with deficits in cognitive function, including attention, working memory,

151 consumption were positively associated with cognitive function, together accounting for 20% (95% CI

152 utcomes assessed included measures of global cognitive function, verbal episodic memory, semantic flu

153 A1 pyramidal cells and hippocampal-dependent cognitive function.

154 (AD) is a progressive disorder that affects cognitive function.

155 and molecular tools and the study of higher cognitive function.

156 ing precisely localized synapses, calibrates cognitive function.

157 ptoms and counterregulation while preserving cognitive function.

158 oci shared between schizophrenia and general cognitive function.

159 ic, gastrointestinal, and endocrine disease; cognitive function; serum nutrient levels; and others (t

160 how that their assumptions are incorrect for cognitive-functional linguistics, exposing converging pe

161 m/meaning pairings between generativists and cognitive-functional linguists that we hope will spark t

162 ns in individual posterior lobules, in which cognitive functioning seems preponderant, are still unkn

163 ciated with improved verbal memory and other cognitive functions in older men with low testosterone a

164 Accordingly, NPY was shown to modulate cognitive functions in rodents.

165 hat older patients with reduced preoperative cognitive functions or who develop postoperative deliriu

166 pervasive impairments in clinically relevant cognitive functions, including general intelligence, exe

167 not associated with improved memory or other cognitive functions.

168 g temporal flexibility upon sensorimotor and cognitive functions.

169 ain rhythms and is present during a range of cognitive functions.

170 ex nature of human cognition has resulted in cognitive genomics lagging behind many other fields in t

171 in each MR imaging category: (a) biopsy with cognitive guidance, (b) biopsy with MR imaging/US fusion

172 , we built a prediction algorithm for global cognitive impairment (defined as Mini Mental State Exami

173 spectroscopic imaging in subjects with mild cognitive impairment (MCI), patients with Parkinson dise

174 tight relationship between tau pathology and cognitive impairment across the Alzheimer's disease spec

175 hing is associated with an increased risk of cognitive impairment and a small worsening in executive

176 ation of neuroanatomical alterations in mild cognitive impairment and Alzheimer's disease that can co

177 daily living were pooled separately for mild cognitive impairment and dementia trials.

178 gomers in human brain tissue correlated with cognitive impairment and reductions in synapsin expressi

179 hrenia Consensus Cognitive Battery (MCCB) in cognitive impairment associated with schizophrenia and t

180 nosed Parkinson's disease, the occurrence of cognitive impairment at 2 year follow-up can be predicte

181 ation in a majority of amyloid positive mild cognitive impairment cases, its cortical distribution ov

182 tion of 18% in microglial activation in mild cognitive impairment cohort over 14 months, which was as

183 isk score had an increased hazard for global cognitive impairment compared with those in the lowest q

184 ntrols, 3 with a history of TBI, 2 with mild cognitive impairment due to suspected Alzheimer disease)

185 alizing and social participation may prevent cognitive impairment following natural disaster.

186 Collectively, our results illustrate that cognitive impairment in zebrafish could be associated wi

187 Purpose Cognitive impairment is well-recognized after myeloablat

188 tion of synaptic activity is associated with cognitive impairment observed in a number of psychiatric

189 During 24569 person-years, mild cognitive impairment was diagnosed in 104 (5.1%) individ

190 nabis use, such as addiction, psychosis, and cognitive impairment) than cannabis with lower concentra

191 ely healthy controls, 197 patients with mild cognitive impairment, and 180 patients with AD with deme

192 upportive sign, not only for the presence of cognitive impairment, but also for cerebral small vessel

193 rillary tangle (NFT) formation, resulting in cognitive impairment.

194 othesis that cortical tau is associated with cognitive impairment.

195 y obvious developmental defects nor signs of cognitive impairment.

196 s potential use in the treatment of vascular cognitive impairment.

197 ave several concurrent medical disorders and cognitive impairment.

198 ne: hazard ratio [HR] = 0.57, p < 0.05; mild cognitive impairment: HR = 0.19, p < .01), indicating th

199 g provision included: caring for people with cognitive impairment; managing the emotions of patients,

200 These radiation-induced cognitive impairments are accompanied by functional and

201 +/-) mice that may contribute to epilepsy or cognitive impairments associated with lissencephaly.

202 he Rho-GAP oligophrenin-1 is associated with cognitive impairments in both human and mouse.

203 aumatic brain injury (B-TBI) induced lasting cognitive impairments in novel object recognition and le

204 cell/circuit underpinnings that may underlie cognitive impairments in offspring of mothers that abuse

205 hn1 deficiency in the mouse generated severe cognitive impairments, characterized by both a high occu

206 wide range of AD-like pathophysiological and cognitive impairments.

207 neural damage, often resulting in long-term cognitive impairments.

208 Exercise-induced cognitive improvements have traditionally been observed

209 reduced Abeta-related pathology coupled with cognitive improvements in an AD APP/PS1 transgenic mouse

210 indicated that this resulted from increased cognitive load during language switches.

211 The high cognitive load required to navigate such a workflow is d

212 ivity patterns linked to increased reward or cognitive load.

213 skeleton between groups, and correlated with cognitive measures at baseline and following 12 weeks of

214 Successful ageing was defined as good cognitive, motor, and respiratory functioning, along wit

215 nation, including disability status, visual, cognitive, motor, and sensory testing, as well as qualit

216 t reveal generic mechanisms of plasticity in cognitive networks and inform models of language reorgan

217 hich we investigated the treatment effect on cognitive, neuropsychiatric, and health-related quality-

218 ith poor functional outcome (P = 0.04), poor cognitive outcome (P = 0.03), post-stroke anxiety (P = 0

219 ess of stimulation status, may be related to cognitive outcome at the individual patient level.

220 ve is likely essential for both interpreting cognitive outcomes associated with CTE and for developin

221 tern significantly explained the variance in cognitive performance and clinical outcome measures, ind

222 Although HIV participants had slightly lower cognitive performance and start index than SN at baselin

223 Cognitive performance differed as a function of depressi

224 n neurotoxic metal, is associated with lower cognitive performance during childhood.

225 the interest of CB1R as a target to improve cognitive performance during early nicotine withdrawal.

226 us Cognitive Battery was utilized to measure cognitive performance in a subsample of 39 patients.

227 and semantic knowledge, leading to preserved cognitive performance in patients with AD pathology.

228 on neurons consistently resulted in enhanced cognitive performance in working memory and object recog

229 We find that poorer cognitive performance is associated with weaker FC tempo

230 Data on cognitive performance tests at the 4-y re-examinations w

231 subjective memory concerns, poorer baseline cognitive performance, and family history of dementia.

232 hierarchy in the socioeconomic marker) with cognitive performance, cognitive decline, and dementia (

233 These individuals showed lower cognitive performance, increased CDR-SOB, higher amyloid

234 upposed to mediate sleep-wake regulation and cognitive performance.

235 the alternative splicing of tau exon 10, and cognitive performance.

236 sures of brain activity, choice behavior, or cognitive performance.SIGNIFICANCE STATEMENT Engagement

237 counted for extra variance in both motor and cognitive performances, with cerebellar lesion volume, c

238 in misregulation underlies the circadian and cognitive phenotypes displayed by the Drosophila fragile

239 This is the largest study on the cognitive phenotypes of CNVs to date.

240 Linguistic and cognitive phenotypes that were highly associated with FX

241 tially increased by also evaluating familial cognitive potential.

242 n human genome evolution, and possibly human cognitive predominance.

243 increase collectivism and honor-based go-to cognitive procedures.

244 It is a ubiquitous cognitive process resulting in lapses of attention.

245 ds to shifts of connectivity and overlapping cognitive processes along a posterior-anterior vmPFC axi

246 tiplex topology is an important proxy of the cognitive processes of acquisition, capable of capturing

247 enous brain oscillations, thereby modulating cognitive processes supported by those brain rhythms.

248 ead gain signals affecting already available cognitive processes underlies the maturation of cognitio

249 an be achieved by accurately mirroring human cognitive processes.

250 t contributions to decision making and other cognitive processes.

251 crucial for neuronal development and higher cognitive processes.

252 ction-Speech task) and activation related to cognitive processing (non-verbal decision making).

253 Cortical cognitive processing involves gamma oscillations, which

254 ve phase of the stimulation and the internal cognitive processing state.

255 ontal cortex is responsible for higher order cognitive processing, and prefrontal dysfunction is beli

256 electrophysiological measures of sensory and cognitive processing, we found that PSZ were actually su

257 itive systems engineering (CSE), and applied cognitive psychology.

258 haviors may serve both biological and social-cognitive purposes during development.

259 These effects were specific to cognitive rather than affective ToM.

260 t-specific changes were observed only during cognitive reappraisal of negative images.

261 Our capacity for higher cognitive reasoning has a measurable limit.

262 an initial resting-state scan, followed by a cognitive reasoning task involving different levels of c

263 nt a flexible mechanism through which higher-cognitive representations, such as value, can modulate e

264 Considering aspects of cognitive reserve is likely essential for both interpret

265 sking requires individuals to allocate their cognitive resources across different tasks.

266 ort exertion and how we manage those limited cognitive resources.

267 s-emotional eating, uncontrolled eating, and cognitive restraint-were measured through the use of a v

268 Patients scoring in the highest quartile for cognitive risk score had an increased hazard for global

269 This is the first study to demonstrate a cognitive role related to alERC volume in humans.

270 Research in cognitive science suggests that school achievement could

271 Moderate disability was defined as a cognitive score of 70 to 84 and either GMFCS level 2, ac

272 The standardized difference (SD) in cognitive scores between low-birth-weight and normal-bir

273 m of and opportunities for prevention of the cognitive sequelae of these risk factors in midlife.

274 cent human study demonstrated that demanding cognitive shifts could recruit the DMN, yet it is unknow

275 domized to a teaching intervention targeting cognitive skills needed to challenge a superior's decisi

276 rkable development in social, emotional, and cognitive skills.

277 INTERPRETATION: Childhood cognitive, social, behavioural, and emotional impairment

278 ft sensorimotor circuits, during an adaptive cognitive state, can unmask latent plastic potential tha

279 ughts between high-level internally directed cognitive states, when thinking about the self, the pers

280 l progression, and this depended on baseline cognitive status (subjective cognitive decline: hazard r

281 tter on Alzheimer's Disease Assessment Scale-cognitive subscale (ADAS-Cog; p=0.011) and Mini-Mental S

282 We now describe the results of the MS-STAT cognitive substudy, in which we investigated the treatme

283 lar areas implicated for motor (PSP, MSA) or cognitive symptoms (FTD, ALS, PSP) in the diseases.

284 n disorders and shows promise in alleviating cognitive symptoms in some AD patients.

285 emerged: epidemiology, quality improvement, cognitive systems engineering (CSE), and applied cogniti

286 representation is used in the execution of a cognitive task.

287 However, cognitive tasks designed to assess visual-spatial attent

288 traction was tested during motor or nonmotor cognitive tasks.

289 itment of prefrontal regions across multiple cognitive tasks.

290 variations in the performance of animals on cognitive test batteries analogous to those of humans?

291 ting for 20% (95% CI 17%-23%) of variance in cognitive test scores.

292 months on a composite Z score combining four cognitive tests (free and total recall of the Free and C

293 We analyzed the performance on seven cognitive tests of carriers of 12 CNVs associated with s

294 Before undertaking cognitive tests, a randomly selected subset of our sampl

295 Commercial adaptive cognitive training appears to have no benefits in health

296 ocognitive interventions, including auditory cognitive training in SZ.

297 T group received 40 sessions of computerized cognitive training over an eight-week period.

298 training with either a commercial web-based cognitive training program or web-based video games that

299 intervention (43 group sessions integrating cognitive training, physical activity, and nutrition, an

300 1 loci jointly influencing schizophrenia and cognitive traits were identified: 2 loci shared between