ライフサイエンスコーパス: cognitive aging

1 all longitudinal research on determinants of cognitive aging.

2 inating diseases, psychiatric disorders, and cognitive aging.

3 ticocortical "disconnection" partly explains cognitive aging.

4 nd Alzheimer's disease, as well as in normal cognitive aging.

5 emory are often considered a core feature of cognitive aging.

6 e domains or global cognitive function or on cognitive aging.

7 for Alzheimer's disease, schizophrenia, and cognitive aging.

8 critical for understanding genetic risk for cognitive aging.

9 ive function, global cognitive function, and cognitive aging.

10 tical tissue is the foundation of successful cognitive aging.

11 ve aspects, were associated with accelerated cognitive aging.

12 s to evaluate their unique associations with cognitive aging.

13 ippocampal morphology across the spectrum of cognitive aging.

14 varied among international cohort studies of cognitive aging.

15 tal fat intake itself, appeared to influence cognitive aging.

16 could be a promising strategy for reversing cognitive aging.

17 ry is one of the most salient alterations in cognitive aging.

18 ence of a gene x environment interaction for cognitive aging.

19 mer's disease (AD) but also occurs in normal cognitive aging.

20 to represent a ubiquitous characteristic of cognitive aging.

21 egion important for memory and implicated in cognitive aging.

22 ocyte n-3 content are associated with better cognitive aging.

23 amined the effects of food supplement use on cognitive aging.

24 tween the deficiency of ovarian hormones and cognitive aging.

25 Estrogen withdrawal accelerated the rate of cognitive aging.

26 tients, neuroimaging studies, and studies of cognitive aging.

27 n primates, and humans that demonstrates how cognitive aging affects the navigational computations su

28 old enrolled in a population-based study of cognitive aging and 37 self-selected volunteers aged 30

29 nalysis of trials of n-3 PUFA supplements in cognitive aging and dementia prevention, and they suppor

30 or therapies to combat memory loss in normal cognitive aging and dementia.

31 dow of opportunity hypothesis in relation to cognitive aging and dementia.

32 e provides an empirical yet general model of cognitive aging and development.

33 s, a finding with important implications for cognitive aging and early detection of AD.

34 entify contexts and mechanisms of successful cognitive aging and give science and society a hint abou

35 dings highlight sources for heterogeneity in cognitive aging and may hold useful information for cogn

36 Common genetic variants may underlie both cognitive aging and risk of schizophrenia.

37 revention, and they support heterogeneity in cognitive aging and, possibly, in Alzheimer disease.

38 ors that contribute to risk or resilience in cognitive aging, and 2) whether, at old age (25 months),

39 e neural processes concerned with cognition, cognitive aging, and mood, but findings are inconsistent

40 confounding by neuroselection in research on cognitive aging, and they suggest the possibility that e

41 ents indicate that individual differences in cognitive aging are more strongly tied to functional alt

42 ons, but the neural correlates of successful cognitive aging are not well known.

43 tic and molecular mechanisms responsible for cognitive aging are not well understood.

44 el for studying the neurobiological basis of cognitive aging, because they are vulnerable to age-rela

45 -0.02), which was equivalent to accelerating cognitive aging by about 4 years, as observed in this po

46 ndicating that berry intake appears to delay cognitive aging by up to 2.5 years.

47 unted for by peripheral sensory problems but cognitive aging can also be a contributing factor.

48 These variations in cognitive aging can be related to their neural bases via

49 al spatial representations in a rat model of cognitive aging characterized by individual differences

50 ecline of the dopamine (DA) system in normal cognitive aging, DA neuromodulation is one plausible mec

51 Human cognitive aging differs between and is malleable within

52 That is, cognitive aging does not spell doom for financial decisi

53 rs may be critical targets for prevention of cognitive aging even before middle age.

54 ing results have recast our framework around cognitive aging from one of decline to one emphasizing p

55 idence of powerful individual differences in cognitive aging has sharpened focus on identifying biolo

56 Rodent models of cognitive aging have focused on water maze learning and

57 Thus, these data reconcile two cognitive aging hypotheses by revealing that an interact

58 hormone status can broadly influence normal cognitive aging in monkeys, affecting capacities mediate

59 sitive to hippocampal system dysfunction and cognitive aging in monkeys.

60 ng, a longitudinal population-based study of cognitive aging in Olmsted County, Minnesota.

61 g, a longitudinal, population-based study of cognitive aging in Olmsted County, Minnesota.

62 ele and generalize the role of this locus to cognitive aging in the general population.

63 ing a detailed neuropsychological account of cognitive aging in the monkey.

64 tribution of erythrocyte n-3 PUFA content to cognitive aging in the presence or absence of the APOE e

65 that hormone replacement therapy may benefit cognitive aging, in part by promoting mitochondrial and

66 st that hormone replacement therapy benefits cognitive aging, in part by retaining complex synaptic o

67 Cognitive aging is associated with impairments in these

68 We propose that successful cognitive aging is determined by interactions both withi

69 cted by APOE genotype and that the course of cognitive aging is subject to selective alteration by a

70 One mechanism hypothesized to contribute to cognitive aging is the failure to recruit specialized ne

71 of homocysteine lowering to slow the rate of cognitive aging is uncertain.

72 tent to which social relationships influence cognitive aging is unclear.

73 cipation on dementia incidence in studies of cognitive aging is unknown.

74 theories of behavioral dedifferentiation in cognitive aging literature.

75 Typical cognitive aging may be defined as age-associated changes

76 tions such as depression, schizophrenia, and cognitive aging may result from the functional impairmen

77 suggest that one mechanism behind successful cognitive aging might be preservation of HC function com

78 ies linking active lifestyle with successful cognitive aging might be subject to bias from "neurosele

79 A classification of normal cognitive aging, mild cognitive impairment, and dementia

80 Three competing models of cognitive aging (neural compensation, capacity limitatio

81 e strategies, we investigated the effects of cognitive aging on the selection and adoption of navigat

82 ormation processing speed in nonpathological cognitive aging or in lifelong-stable processes.

83 equated to 0.02 y (95% CI: -0.10, 0.13 y) of cognitive aging per year and excluded reductions of >1 m

84 tervention as a viable method to curtail the cognitive aging process.

85 n many studies and is especially relevant in cognitive aging research because cognitive impairment st

86 studies with high mortality, as is common in cognitive aging research.

87 Neurobiological studies of stress and cognitive aging seldom consider white matter despite ind

88 l lobe networks and ultimately contribute to cognitive aging.SIGNIFICANCE STATEMENT We report that lo

89 lationship between two leading hypotheses of cognitive aging, the inhibitory deficit and the processi

90 That is, cognitive aging theories can be specific to the neural n

91 sized that exposure to stress may accelerate cognitive aging, though few studies have directly tested

92 These findings broaden the concept of cognitive aging to include evidence of Alzheimer's disea

93 ive sparing of familiarity observed in human cognitive aging to rats, and suggest a common age-relate

94 classification of MCI, dementia, and normal cognitive aging was adjudicated by an expert consensus p

95 ss in old age is a foundation for successful cognitive aging when, instead, it is a lifelong associat

96 ed in the Women's Health Initiative Study of Cognitive Aging (WHISCA) was administered.