ライフサイエンスコーパス: cognitive dysfunction

1 disorders and may be related to symptoms of cognitive dysfunction.

2 es, which result in brain growth defects and cognitive dysfunction.

3 peptide in the brain, loss of synapses, and cognitive dysfunction.

4 antial evidence linking these alterations to cognitive dysfunction.

5 plicated in psychopathology characterized by cognitive dysfunction.

6 ands harboured additional phenotypes such as cognitive dysfunction.

7 njury-induced neuroinflammatory sequelae and cognitive dysfunction.

8 for PD, in parallel with the development of cognitive dysfunction.

9 docannabinoid signaling and cannabis-induced cognitive dysfunction.

10 umented association between chemotherapy and cognitive dysfunction.

11 that otherwise leads to neuronal injury and cognitive dysfunction.

12 ith IAH, and attenuates hypoglycemia-induced cognitive dysfunction.

13 depressive disorder (MDD) who self-reported cognitive dysfunction.

14 zures that may be fundamentally connected to cognitive dysfunction.

15 tor for the development of schizophrenia and cognitive dysfunction.

16 strongly predicts psychiatric disorders and cognitive dysfunction.

17 ission, have been associated with persistent cognitive dysfunction.

18 aviours are a popular feature in theories of cognitive dysfunction.

19 rovascular disease are at increased risk for cognitive dysfunction.

20 related psychiatric diseases associated with cognitive dysfunction.

21 compensate for tissue damage and to prevent cognitive dysfunction.

22 tients and correlate with disease-associated cognitive dysfunction.

23 ect against neurodegeneration and associated cognitive dysfunction.

24 lain why TBI patients are more vulnerable to cognitive dysfunction.

25 nxiety, or compensatory processes related to cognitive dysfunction.

26 ive cognitive change (POCC) or postoperative cognitive dysfunction.

27 e incidence, severity, and duration of acute cognitive dysfunction.

28 be a therapeutic target for the treatment of cognitive dysfunction.

29 resolved), and 1 (5%) patient developed mild cognitive dysfunction.

30 mins has been linked to mood disturbance and cognitive dysfunction.

31 onship between poor physical performance and cognitive dysfunction.

32 ay represent a promising approach to reverse cognitive dysfunction.

33 ism by which chronic stress may promote mPFC cognitive dysfunction.

34 and their alterations are linked to various cognitive dysfunction.

35 FC) is augmented in a genetic mouse model of cognitive dysfunction.

36 chemokine CCL11 shown to be associated with cognitive dysfunction.

37 on of microRNAs in psychiatric disorders and cognitive dysfunction.

38 the molecular and cellular bases underlying cognitive dysfunction.

39 ore the onset of age-related gross motor and cognitive dysfunction.

40 sing a model of anticholinergic drug-induced cognitive dysfunction.

41 post-AT psychopathologies including PTSD and cognitive dysfunction.

42 ase onset and are more likely to demonstrate cognitive dysfunction.

43 -related cerebral injury could contribute to cognitive dysfunction.

44 n and genetic liability to schizophrenia and cognitive dysfunction.

45 chemicals exacerbated the extent of mood and cognitive dysfunction.

46 his impact of SNP on affective disorders and cognitive dysfunction.

47 have been associated with mood disorders and cognitive dysfunction.

48 eutic target for treatment of stress-induced cognitive dysfunction.

49 der, motor signs of PD can be exacerbated by cognitive dysfunction.

50 e severity, cerebrovascular comorbidity, and cognitive dysfunction.

51 tain cortical regions that contribute to the cognitive dysfunction.

52 l increase in prevalence of diabetes-related cognitive dysfunction.

53 ase including stroke are important causes of cognitive dysfunction.

54 behaviors and of disease-relevant social and cognitive dysfunction.

55 s been implicated in affective disorders and cognitive dysfunction.

56 tion of gray matter, which may contribute to cognitive dysfunction.

57 in synthesis, have been linked to autism and cognitive dysfunction.

58 al for AD and other diseases associated with cognitive dysfunction.

59 yR2 remodeling contributes to stress-induced cognitive dysfunction.

60 HOMA-IR >2.6) had 47% (9-99%) larger odds of cognitive dysfunction.

61 increases the risk for cognitive decline and cognitive dysfunction.

62 ciated with neurological deficits, including cognitive dysfunction.

63 radiations that put them at risk for severe cognitive dysfunction.

64 ity in the default mode network (DMN) before cognitive dysfunction.

65 al death in the hippocampus and long-lasting cognitive dysfunction.

66 afflicted with many complications including cognitive dysfunction.

67 n patients with chronic fatigue syndrome and cognitive dysfunction.

68 olinergic system in healthy cognition and in cognitive dysfunction.

69 a promising new target for the treatment of cognitive dysfunction.

70 tion and global, frontal and visuoperceptive cognitive dysfunction.

71 mong these precursors of type 2 diabetes and cognitive dysfunction.

72 sed risk of neurological disease, cancer and cognitive dysfunction.

73 tic targets for preventing infection-induced cognitive dysfunction.

74 id in adolescence does not produce long-term cognitive dysfunction.

75 l features and appear to interact in driving cognitive dysfunction.

76 importance in a model of 22q11.2-associated cognitive dysfunction.

77 factor for development of schizophrenia and cognitive dysfunction.

78 glycemia and attenuates hypoglycemia-induced cognitive dysfunction.

79 etic risk of schizophrenia may contribute to cognitive dysfunction.

80 ovel therapeutic approaches for ameliorating cognitive dysfunction.

81 could have a key role in the development of cognitive dysfunction.

82 ally linking Abeta pathology to neuronal and cognitive dysfunction.

83 lications such as delirium and postoperative cognitive dysfunction.

84 to investigate the function of Calstabin2 in cognitive dysfunction.

85 can prevent anesthesia-induced postoperative cognitive dysfunction.

86 PAMs) are currently being developed to treat cognitive dysfunction.

87 cial for Abeta-induced synaptic toxicity and cognitive dysfunction.

88 iated with 44% (9-91%) larger probability of cognitive dysfunction.

89 of oxidative stress, neurodegeneration, and cognitive dysfunctions.

90 pathy, 0, 1, 0, and 0, respectively; and for cognitive dysfunction, 3, 1, 1, and not analyzed, respec

91 In the present study we focus on cognitive dysfunction, a core feature of schizophrenia (

92 known whether these shared manifestations of cognitive dysfunction across diagnostic categories also

93 The appearance of cognitive dysfunction after cardiac surgery in the absen

94 Evidence of cognitive dysfunction after pmTBI was observed in the do

95 development of posttraumatic epilepsy and in cognitive dysfunction after traumatic brain injury, but

96 le cognitive subscale scores as a measure of cognitive dysfunction (Alzheimer's Disease Neuroimaging

97 Diabetes is associated with cognitive dysfunction and an increased risk of dementia.

98 ted with the 22q11DS, which may be linked to cognitive dysfunction and an increased risk to develop s

99 plasma MMA, which have been associated with cognitive dysfunction and anemia in NHANES and in other

100 in sensory processing underlie more complex cognitive dysfunction and are in turn affected by higher

101 likely explanation for its association with cognitive dysfunction and ASD.

102 , an RNA-binding protein implicated in human cognitive dysfunction and autism.

103 ms of mGluR5 dysfunction in a mouse model of cognitive dysfunction and autism.

104 dely used in breast cancer treatment, causes cognitive dysfunction and changes in CNS metabolism, hip

105 These changes may contribute to the cognitive dysfunction and circuit hyperexcitability asso

106 mimics DS/AD pathology, notably age-related cognitive dysfunction and degeneration of basal forebrai

107 nt LRRK2 pathogenesis.SIGNIFICANCE STATEMENT Cognitive dysfunction and dementia are common features o

108 examine the neuropathological substrates of cognitive dysfunction and dementia in Parkinson disease

109 with risk of congestive heart failure (CHF), cognitive dysfunction and depression.

110 ongoing neurodegeneration interact to induce cognitive dysfunction and episodes of delirium.

111 CFS) have similar profiles of pain, fatigue, cognitive dysfunction and exertional exhaustion.

112 al adverse events included transient grade 3 cognitive dysfunction and grade 1-2 seizures (n=3 [17%])

113 evidence of an association between mood and cognitive dysfunction and hippocampal pathology epitomiz

114 mulation in aging blood promotes age-related cognitive dysfunction and impairs neurogenesis, in part

115 d emergence of internally generated imagery, cognitive dysfunction and influence of dopaminergic drug

116 rrent epileptiform discharge, which provoked cognitive dysfunction and memory deficits without affect

117 on containing a polymorphism associated with cognitive dysfunction and mood disorders.

118 variants predict a more rapid progression of cognitive dysfunction and motor symptoms in patients wit

119 pha7 nicotinic receptor partial agonists for cognitive dysfunction and negative symptoms in schizophr

120 otinic receptor partial agonist, TC-5619, on cognitive dysfunction and negative symptoms in subjects

121 oviral therapy (ART), HIV infection promotes cognitive dysfunction and neurodegeneration through pers

122 d expression of imprinted genes is linked to cognitive dysfunction and neuropsychological disorders,

123 s little to suggest how reduced Glut1 causes cognitive dysfunction and no optimal treatment for Glut1

124 therapies to prevent or treat postoperative cognitive dysfunction and other forms of cognitive decli

125 uthors sought to clarify the extent to which cognitive dysfunction and personality traits are shared

126 sparing of TBI-induced hippocampal-dependent cognitive dysfunction and reduced proinflammatory activa

127 iscusses clinical features of post-operative cognitive dysfunction and reviews the evidence supportin

128 of the most common genetic risk factors for cognitive dysfunction and schizophrenia, we found that g

129 e rats produced depression-like changes with cognitive dysfunction and selective cell death in the in

130 predispose patients to development of future cognitive dysfunction and sensitisation to further injur

131 rovides insights into the pathophysiology of cognitive dysfunction and the mechanisms involved in rec

132 i detected by serial/extended EEG, transient cognitive dysfunction, and good seizure control and tole

133 association cortices was strongly linked to cognitive dysfunction, and likely reflects the impact of

134 MADRS were grouped into depression, anxiety, cognitive dysfunction, and neurovegetative symptom dimen

135 However, the anxiety, cognitive dysfunction, and neurovegetative symptom dimen

136 chizophrenia that is broadly associated with cognitive dysfunction, and they support hippocampal acti

137 sorders including delirium and postoperative cognitive dysfunction are common postanesthesia complica

138 n, neurodegeneration-associated changes, and cognitive dysfunction arising after sepsis recovery.

139 Use of post-operative cognitive dysfunction as a marker of brain injury is pro

140 metabolic syndrome have been associated with cognitive dysfunction as well.

141 These results indicate that early cognitive dysfunction, as measured by the SORT, occur pr

142 atal exposure, can initiate neurological and cognitive dysfunction, as well as memory impairment.

143 and provide new insights into the origin of cognitive dysfunction associated with developmental inte

144 ogenic role of PVMs in the neurovascular and cognitive dysfunction associated with hypertension and i

145 ppocampal structural plasticity may underlie cognitive dysfunction associated with influenza infectio

146 eural circuitry that underlie behavioral and cognitive dysfunctions associated with FXS.

147 fering from psychosis and has been linked to cognitive dysfunction, audiovisual hallucinations, and n

148 symptoms including intellectual disability, cognitive dysfunction, autism and myriad other behaviora

149 rationale for survival of humans with severe cognitive dysfunction bearing a truncating mutation in t

150 order is associated with variable degrees of cognitive dysfunction, but no consistent functional biom

151 rbidities including anxiety, depression, and cognitive dysfunction, but the mechanism for these is no

152 ligomers were proposed to cause synaptic and cognitive dysfunction by binding to PrP(c).

153 The findings suggest that cognitive dysfunction can be considered a sign of prodro

154 ciousness, decreased responsiveness or other cognitive dysfunctions can persist.

155 One third of them exhibited cognitive dysfunction (CD) according to the PHES (<-4).

156 Cognitive dysfunction characterizes all the various form

157 s with non-NET cancer also demonstrated some cognitive dysfunction compared with norms, the patients

158 spinal fluid (CSF) and developed progressive cognitive dysfunction despite ventricular drainage.

159 Traumatic brain injury (TBI) can induce cognitive dysfunction due to the regional accumulation o

160 in, contributing to the onset/progression of cognitive dysfunction during aging.

161 c hypoactivity is thought to be important in cognitive dysfunction during delirium, and acute systemi

162 Many healthy women with no history of cognitive dysfunction experience subjective executive di

163 Patient-reported outcomes related to cognitive dysfunction (F = 7.27; P = .002) and psycholog

164 erative side-effects (including delirium and cognitive dysfunction, fatigue, dizziness, pain, and gas

165 , with the symptom dimensions of anxiety and cognitive dysfunction fluctuating and worsening, respect

166 n hippocampal neuron morphology may parallel cognitive dysfunction following peripheral infection wit

167 reased hospital readmissions and substantial cognitive dysfunction for 1 year following surgery.

168 at is characterized by acute inattention and cognitive dysfunction, for which prior dementia is the m

169 This HO-1 deficiency correlated with cognitive dysfunction, HIV replication in the CNS, and n

170 E knock-out (KO) mice have synaptic loss and cognitive dysfunction; however, these findings are compl

171 rged in systemic inflammation, postoperative cognitive dysfunction, immune suppression and cell signa

172 od-brain barrier has long been implicated in cognitive dysfunction in aging and neurodegeneration, bu

173 Patients with CS reported greater cognitive dysfunction in all cognitive domains than both

174 ggesting a novel target for the treatment of cognitive dysfunction in Alzheimer's disease.

175 novel potential target for the treatment of cognitive dysfunction in Alzheimer's disease.

176 emia and microvascular disease contribute to cognitive dysfunction in both type 1 and type 2 diabetes

177 homeostasis as key mechanisms important for cognitive dysfunction in children with NF1.

178 wn syndrome (DS) is the most common cause of cognitive dysfunction in children.

179 Persistent cognitive dysfunction in depression and bipolar disorder

180 (OFC) that we have used previously to model cognitive dysfunction in depression.

181 es findings with brain MRI that may underlie cognitive dysfunction in diabetes.

182 se of selective GABA(A) alpha5 NAMs to treat cognitive dysfunction in DS.

183 inflammatory events often precipitate acute cognitive dysfunction in elderly and demented population

184 tracerebral hemorrhage, ischemic stroke, and cognitive dysfunction in elderly patients with and witho

185 Cognitive dysfunction in fibromyalgia patients has been

186 Cognitive dysfunction in first-degree relatives is more

187 oping neocortical circuits may contribute to cognitive dysfunction in FXS.

188 tions for improving how we measure and model cognitive dysfunction in human disorders in animals, thu

189 bute to the circuitry alterations underlying cognitive dysfunction in individuals with SZ.

190 Cognitive dysfunction in lacunar stroke patients may com

191 in proteins link Abeta and hyperglycaemia to cognitive dysfunction in MetS/T2DM and AD.

192 However, the mechanisms underlying severe cognitive dysfunction in MS are not well understood.

193 ely prevent neurodegeneration and associated cognitive dysfunction in MS.

194 of CXCL12/CXCR4 as a contributing factor to cognitive dysfunction in neuroAIDS.

195 that altered O-GlcNAc levels could underlie cognitive dysfunction in neurological diseases.

196 ects on basic stimulus processing extends to cognitive dysfunction in neuropathological conditions in

197 This is significant because cognitive dysfunction in normative and pathological agin

198 Increased focus on symptoms of cognitive dysfunction in older patients with rosacea may

199 that PKA dysregulation in the mPFC underlies cognitive dysfunction in Ophn1-deficient mice, as assess

200 l connectivity (FC) are important factors in cognitive dysfunction in patients with multiple sclerosi

201 rontal cortex (PFC) has been associated with cognitive dysfunction in patients with schizophrenia and

202 a correlation between sleep disturbances and cognitive dysfunction in patients with schizophrenia, th

203 terventions that may slow the progression of cognitive dysfunction in PD.

204 abnormal pattern of neural activity underlie cognitive dysfunction in PP-MS, and that CLs possibly pl

205 ontribute to abnormal cortical formation and cognitive dysfunction in preterm survivors.

206 al circuits could at least in part influence cognitive dysfunction in psychosis and its treatment.

207 ith psychosis, 2) tests a continuum model of cognitive dysfunction in psychotic disorders, 3) reports

208 ng alteration in synaptic function underlies cognitive dysfunction in RAB39B-related disorders.

209 l depletion of central monoamine systems and cognitive dysfunction in rats and humans.

210 s indicate that forniceal DBS might mitigate cognitive dysfunction in RTT.

211 results on measures of negative symptoms and cognitive dysfunction in schizophrenia and was well tole

212 important link between GABA transmission and cognitive dysfunction in schizophrenia because they show

213 Identification of biomarkers for cognitive dysfunction in schizophrenia is a priority for

214 Cognitive dysfunction in schizophrenia is associated wit

215 Cognitive dysfunction in schizophrenia is one of the mos

216 ecently proposed hyperfocusing hypothesis of cognitive dysfunction in schizophrenia proposes that peo

217 ectivity are critical determinants of social cognitive dysfunction in schizophrenia, and thus represe

218 ntal cortex (DLPFC) appears to contribute to cognitive dysfunction in schizophrenia, whereas psychosi

219 onnectivity in the pathophysiology of social cognitive dysfunction in schizophrenia.

220 ons in GABA signaling drive certain forms of cognitive dysfunction in schizophrenia.

221 ssing speed (PS; beta=0.74; P=0.003), a core cognitive dysfunction in schizophrenia.

222 substrate for altered gamma oscillations and cognitive dysfunction in schizophrenia.

223 d mechanistic account of multiple aspects of cognitive dysfunction in schizophrenia.SIGNIFICANCE STAT

224 ion of GIRK-dependent signaling may underlie cognitive dysfunction in some disorders.

225 aging are associated with varying degrees of cognitive dysfunction in stroke, cerebral small vessel d

226 The results show that, despite broad cognitive dysfunction in the acute phase, patients with

227 The mechanisms underlying this postoperative cognitive dysfunction in the adult brain remain poorly u

228 ts its therapeutic effects on stress-induced cognitive dysfunction in the OFC.

229 There is a hidden epidemic of cognitive dysfunction in the perioperative setting.

230 inergic deficit that contributes to gait and cognitive dysfunction in these patients.

231 Despite the prominence of cognitive dysfunction in this syndrome, little is known

232 Cognitive dysfunction in type 1 and type 2 diabetes shar

233 uits may have a role in mediating aspects of cognitive dysfunction in underweight individuals with AN

234 s of large-scale brain networks may underlie cognitive dysfunctions in psychiatric and addictive diso

235 tween androgen deprivation therapy (ADT) and cognitive dysfunction, including Alzheimer disease.

236 Stress-induced cognitive dysfunction, including deficits in learning an

237 Cognitive dysfunction, including significant impairments

238 se (PD), with clinical features of motor and cognitive dysfunction indistinguishable from sporadic PD

239 Cognitive dysfunction is a common feature among patients

240 Cognitive dysfunction is a common symptom in many neurop

241 Cognitive dysfunction is a core feature of dementia and

242 Cognitive dysfunction is an early clinical hallmark of H

243 Cognitive dysfunction is common in depression during bot

244 Cognitive dysfunction is common in LLD, particularly exe

245 In schizophrenia, cognitive dysfunction is highly predictive of poor patie

246 PFC cognitive dysfunction is implicated in multiple psychopa

247 on adverse effects, it is uncertain whether cognitive dysfunction is induced in humans by exposure t

248 Cognitive dysfunction is reported in people with cancer.

249 ngs suggest that screening and monitoring of cognitive dysfunction may be important in the assessment

250 n network-level brain architecture, and that cognitive dysfunction may be reflected by abnormal netwo

251 (measured using [(18)F]Florbetapir-PET) and cognitive dysfunction (measured using ADAS-cog) by condu

252 To assess whether cognitive dysfunction might precede motor deficits in tg

253 Because MMSE could be impaired in several cognitive dysfunctions, more specific test should be use

254 espread nervous system dysfunction including cognitive dysfunction, neuropathy and susceptibility to

255 n may be helpful for alleviation of mood and cognitive dysfunction observed in GWI.

256 Sickness behavior and cognitive dysfunction occur frequently by unknown mechan

257 However, there are no reports of cognitive dysfunction occurring prior to this.

258 Cognitive dysfunction occurs after surgery in humans.

259 Cognitive dysfunction occurs in many debilitating condit

260 sts a possible neurobiological mechanism for cognitive dysfunction of this type of PTSD.

261 predict some of the symptoms as well as the cognitive dysfunctions of schizophrenia.

262 at a range of malignancies can elicit severe cognitive dysfunction often referred to as "chemobrain,"

263 ety and probable behaviour disorder, but not cognitive dysfunction or motor severity.

264 not related to developmental delays, general cognitive dysfunction, or history of medication use.

265 P = .04) and were more likely to demonstrate cognitive dysfunction (P = .001).

266 go general anesthesia and surgery experience cognitive dysfunction, particularly memory deficits that

267 nterleukin-1beta (IL-1beta) in postoperative cognitive dysfunction (POCD) in aged rats, we used lapar

268 iminary evidence suggests that postoperative cognitive dysfunction (POCD) is common after lung transp

269 POD can lead to postoperative cognitive dysfunction (POCD), a more prolonged cognitive

270 ue to their potential role in post-operative cognitive dysfunction (POCD).

271 Postoperative cognitive dysfunction, POCD, afflicts a large number of

272 tion can reduce some measures of age-related cognitive dysfunction, possibly through an improvement i

273 disease, skin ulcer, aPL nephropathy, and/or cognitive dysfunction received 2 doses of rituximab (1,0

274 nisms within the white matter accounting for cognitive dysfunction remain unclear.

275 CNS malignancy, progressive and debilitating cognitive dysfunction remains a pressing unmet medical n

276 owever, how the genetic elimination leads to cognitive dysfunction remains unknown.

277 ontributory roles, if any, of SCCD itself in cognitive dysfunction require direct study.

278 -year-old woman with delusional disorder and cognitive dysfunction, respectively.

279 ystem, may play a key role in the widespread cognitive dysfunction seen after traumatic axonal injury

280 o be a particularly important determinant of cognitive dysfunction seen in well-treated HIV-infected

281 new developments for treatments that address cognitive dysfunction should be a priority so that all m

282 e were associated with more severe motor and cognitive dysfunction, supporting a specific contributio

283 al WM damage may have a greater relevance to cognitive dysfunction than physical disability in MS, an

284 OPRI patients had more widespread and severe cognitive dysfunction than the P102L group and this corr

285 hway that could contribute to the social and cognitive dysfunction that accompanies dysregulated mTOR

286 al isolation results in adult behavioral and cognitive dysfunction that correlates with white matter

287 brain cancer elicits progressive and severe cognitive dysfunction that is associated with significan

288 5(E218A) protein leads to survival rates and cognitive dysfunction that mirror human WNV neuroinvasiv

289 g stress and this may underlie affective and cognitive dysfunctions that characterize stress-related

290 uggesting an association between obesity and cognitive dysfunction, this phenomenon has received rela

291 myofascitis (MMF) and the relationship with cognitive dysfunction through the use of PET with (18)F-

292 n this study of MDD adults who self-reported cognitive dysfunction, vortioxetine significantly improv

293 losed that status epilepticus, psychosis and cognitive dysfunction were statistically significant var

294 ric symptoms, seizures, movement disorder or cognitive dysfunction, were identified from 111 paediatr

295 ns leads to increased amyloid deposition and cognitive dysfunction, which are invariable pathological

296 as been shown to specifically replicate this cognitive dysfunction, which has limited its translation

297 iors, such as fatigue, mood alterations, and cognitive dysfunction, which result from changes in cent

298 HIIT attenuated hypoglycemia-induced cognitive dysfunction, which was mainly driven by change

299 rly individuals without clinical evidence of cognitive dysfunction who were randomly assigned to cons

300 mined the trajectory and extent of long-term cognitive dysfunction, with a focus on 1 to 5 years afte