ライフサイエンスコーパス: cohort

1 ive Huntington Observational Research Trial (COHORT).

2 lized Center of Clinically Oriented Research cohort.

3 tified APOC3 homozygous pLoF carriers in our cohort.

4 and five (13%) patients in the every-6-weeks cohort.

5 3-87 years from the population-based Cam-CAN cohort.

6 uded in a unicenter cohort and a multicenter cohort.

7 both the discovery cohort and the validation cohort.

8 A total of 96595 children entered the study cohort.

9 ny of the exon events identified in the TCGA cohort.

10 d Head Injury score < 5a) in the development cohort.

11 lized Center of Clinically Oriented Research cohort.

12 h weight (<1,500 g) in the more recent birth cohort.

13 roangiopathy were included in the derivation cohort.

14 SNPs have not been replicated in a separate cohort.

15 Retrospective interventional cohort.

16 (<18 years) were selected from the U-BIOPRED cohort.

17 vided into 2 groups, a test and a validation cohort.

18 members of the general population comparison cohort.

19 ient survival were not investigated in large cohort.

20 and finger nails collected from a Norwegian cohort.

21 2 (95% CI, 0.73 to 0.92) for the independent cohort.

22 ep disturbance is high in this large Chinese cohort.

23 R V122I amyloidosis comprised the validation cohort.

24 filled the criteria for inclusion in the MAP cohort.

25 older ages and similar in magnitude in each cohort.

26 group of responders that included 40% of the cohort.

27 ached nominal significance in the validation cohort.

28 rdiac magnetic resonance imaging in the same cohorts.

29 cohorts, and from the combined CTD and LVOTD cohorts.

30 CC risk in a prospective study nested in two cohorts.

31 ells of the few first, most represented, age cohorts.

32 not reproducible when tested in independent cohorts.

33 were generally small and inconsistent across cohorts.

34 enhancing discrimination between diagnostic cohorts.

35 val, in two different Ewing Sarcoma clinical cohorts.

36 l survival (OS) in large, multinational PTCL cohorts.

37 ing that will have to be replicated in other cohorts.

38 the 10 mg/kg Q2W and 10 and 20 mg/kg QW/Q2W cohorts.

39 D, with remarkable consistency between the 2 cohorts.

40 ne demographics were well balanced among the cohorts.

41 s few strains occurred in multiple unrelated cohorts.

42 (ST/LV) and long travel/high-volume (LT/HV) cohorts.

43 analysis followed by a meta-analysis across cohorts.

44 ents with relapsed/refractory HL received 2 (cohort 1) or 3 (cohort 2) cycles of weekly BV; PET-negat

45 Among 638 patients in the derivation cohort, 121 (18.9%) had CED.

46 ed/refractory HL received 2 (cohort 1) or 3 (cohort 2) cycles of weekly BV; PET-negative patients (De

47 Cohort 3: five tertiary and four community hospitals.

48 s (range, 6-329 months) for the entire study cohort; 363 patients (63%) underwent surveillance for mo

49 In the test cohort, 46 of 83 (55%) patients showed histological feat

50 In this low-risk elderly cohort, 46% of patients with a nonbacterial AURI were pr

51 Of the 648 subjects in this cohort, 536 (82.7%) were female and the mean age was 55.

52 urvival after 5 years was 38% for the entire cohort (95% CI, 25%-51%); the disease-specific survival

53 In our cohort, advanced age (>67) was the strongest predictor o

54 Prospective, population-based cohort analysis including 21870 participants (20163 free

55 Society Adult Patient Database and a nested cohort analysis of a single center.

56 Observational intent-to-treat cohort analysis using the Veterans Affairs Clinical Case

57 terval [CI], 0.65 to 0.79) for the SPIROMICS cohort and 0.82 (95% CI, 0.73 to 0.92) for the independe

58 ta from 100 patients included in a unicenter cohort and 246 included in a unicenter cohort and a mult

59 enter cohort and 246 included in a unicenter cohort and a multicenter cohort.

60 opkins Center for Mendelian Genomics (BHCMG) cohort and detected 773 HMZ deletion calls (567 homozygo

61 in four (11%) patients in the every-12-weeks cohort and five (13%) patients in the every-6-weeks coho

62 d odds ratios (ORs) were calculated for each cohort and in a combined analysis of all cohorts; longit

63 t between these groups in both the discovery cohort and the validation cohort.

64 sk factors were identified in the derivation cohort and were combined into an overall score, the MEES

65 essed using internal and external validation cohorts and compared to clinical assessment alone.

66 s declined between the 1950s and 1970s birth cohorts and the 2000--2002 birth cohort, despite a highe

67 ommon genetic variants in the identification cohort, and 2 of these associations were replicated.

68 ployed novel strategies to recruit a diverse cohort, and collected biological and environmental sampl

69 tudy results from the CTD cohorts, the LVOTD cohorts, and from the combined CTD and LVOTD cohorts.

70 ed to controls across single- and multi-site cohorts, and increased over 1 year in Parkinson's diseas

71 lex were differentially acquired between the cohorts, and that changes in antibody levels to Apical M

72 , 2-cohort clinical trial in which the first cohort assessed for the safety and efficacy of 12 weeks

73 from two selected disease-specific expansion cohorts at the same study site who had serum samples obt

74 A separate longitudinal sample (cohort B) included 16 MDD patients who underwent MRI at

75 children from the prospective Swedish birth cohort BAMSE (Children, Allergy, Milieu, Stockholm, Epid

76 V vaccination, with 3-dose uptake across age cohorts being about 50%-77%).

77 often unstable and not generalizable due to cohort bias, biological variation and limited sample siz

78 ethylation at 83 CpGs that replicated across cohorts; BMI-related differential methylation was associ

79 risk of developing ROP among an unrestricted cohort but with a reduced risk of ROP among a restricted

80 iding an opportunity to divide patients into cohorts by severity of rod and cone dysfunction.

81 ed individuals (SWIFT-C) is an open-label, 2-cohort clinical trial in which the first cohort assessed

82 osis between PLWH in the North American AIDS Cohort Collaboration on Research and Design and the gene

83 Function and Ageing Study Wales (CFAS-Wales) cohort collected in 2011-2013.

84 re common in the combined Finnish hereditary cohort compared to controls.

85 Genomes Project (phase 3) in 12 case-control cohorts comprising 3,495 anorexia nervosa cases and 10,9

86 trospective analysis of the largest reported cohort, consisting of 182 patients with POAML, diagnosed

87 d case-control studies in the Ovarian Cancer Cohort Consortium to investigate the association between

88 21 prospective cohort, cross-sectional, and case-control studies includ

89 This single-cohort design included all persons born in Denmark (N =

90 We used a matched case-cohort design to estimate the risk of deaths by suicide

91 es and subsequent CVD.With the use of a case-cohort design, we profiled 202 lipid species at baseline

92 using Barlow weights to account for the case-cohort design.

93 1970s birth cohorts and the 2000--2002 birth cohort, despite a higher proportion of the low-birth-wei

94 The majority of behavioural traits in our cohort differed between males and females; however Y chr

95 mer smokers and never smokers in two Swedish cohorts, differing for known MS risk factors.

96 eplanned secondary analysis of a prospective cohort enrolled from January 1 through December 31, 2011

97 that children with a diagnosis of asthma at cohort entry were at 51% increased risk of developing ob

98 n the Amish Complex Disease Research Program cohort exhibited significantly lower postprandial serum

99 In two retrospective case-control cohorts for the evaluation of early-onset myocardial inf

100 odds of daily smoking were observed in both cohorts for those adolescents whose parents separated (f

101 l mortality declined slightly in the overall cohort from 9.3% to 8.9% (P<0.001).

102 d older participating in 14 population-based cohorts from 10 countries in Europe.

103 18 of 33 cohorts from the Collaboration of Observational HIV Epid

104 In two independent clinical cohorts from tissue microarrays (TMA: n = 208 patients)

105 tudy following three sequential, independent cohorts, from a single U.S. health system, through their

106 04 452 European-ancestry individuals from 30 cohorts, genotyped using the Exome Chip.

107 ohort had 306 patients, the first validation cohort had 216, and the second validation cohort had 265

108 on cohort had 216, and the second validation cohort had 265 patients.

109 The discovery cohort had 306 patients, the first validation cohort had

110 Our 300-patient cohort had a median (interquartile range) age of 20 mont

111 enge, which had a fixed sequence, and biopsy cohorts had a gastroscopy with duodenal biopsies and qua

112 AREDS2 participants (discovery cohort) had detailed phenotyping for AMD; other eye cond

113 disease, compared with the remaining patient cohort, had a significantly lower 2-year cumulative HBV

114 The cohort has been linked by Statistics Canada to the Canad

115 bers have benefited as funding of the entire cohort has decreased.

116 ences in the clinical outcomes between the 2 cohorts have not been examined.

117 d 2,922 controls from the 1958 British birth cohort identified an additional 14 regions associated wi

118 distributions, which revealed an additional cohort in years with early ice breakup, lowering the mea

119 arthritis (UA), early RA, and established RA cohorts in comparison with healthy donors.

120 Longitudinal follow up of birth cohorts in diverse environments worldwide will continue

121 kers of Exposure to ARsenic (BEAR) pregnancy cohort, in Gomez Palacio, Mexico.

122 The final analysis cohort included 88 eyes in 3 groups: monthly (n = 19), T

123 The study cohort includes 204485 infants born at 35 weeks' gestati

124 systematic analyses of the entire TCGA NSCLC cohort, including comparisons and contrasts between diff

125 of heterogeneity in the associations across cohorts, including a slightly faster decline (p = 0.021)

126 ta were extracted by investigators from each cohort independently and synthesized by 2 investigators.

127 Enrolment into this cohort is closed, but patients are still being monitored

128 ach cohort and in a combined analysis of all cohorts; longitudinal analyses were also performed for c

129 the models was carried out on the other two cohorts (LR: AUC = 0.69 and CI = 0.67; DM: AUC = 0.86 an

130 In the retrospective cohort, luminal B prostate cancers exhibited the poorest

131 In the derivation cohort, LV ejection fraction </=47%, infarct size >/=19%

132 present and organize data gleaned from these cohorts, many using ideas implicitly or explicitly borro

133 flicting associations in the full and P-VLBW cohorts may reflect true differences, the association of

134 ith CF from 20 years before the contemporary cohort (mean z score increase, 0.57; 95% CI, 0.37-0.77).

135 In 516 subjects (79% of eligible cohort members) who were 13 years old, serum concentrati

136 l confounders collected from a subset of the cohort members.

137 Cohort mortality was significantly higher than the gener

138 in an independent planned myocardial injury cohort (n=15; P<1.33E-04, 1-way repeated measures analys

139 reshold, and subjective odor perception in a cohort (n=161) comprising 36 participants with CKD, 100

140 he Framingham Offspring and Third Generation Cohorts (n=3318; aged 48.9+/-10.3 years), who underwent

141 Of note, 1 in 3 of the deaths in this cohort occurred in women without obstructive CAD, a cond

142 ALSPAC, odds ratio = 1.46; for Pelotas Birth Cohort, odds ratio = 1.98).

143 Materials and Methods A cohort of 113 patients with NSCLC diagnosed between Apri

144 We studied a cohort of 179 patients (from 173 families) with BMF of s

145 moter region was associated with height in a cohort of 227 healthy children, suggesting that HOXA4 ma

146 ormed digital gene expression profiling on a cohort of 245 formalin-fixed, paraffin-embedded tumor sp

147 Prospective cohort of 250 patients admitted to the ICU with coma (Gl

148 insight into this phenomenon, we analyzed a cohort of 2530 related and unrelated hematologically nor

149 A cohort of 26 370 subjects was retrospectively collected

150 A case-control study, nested in a cohort of 2617 five-year survivors of HL diagnosed befor

151 In an independent London-based cohort of 37 participants (23 HTT mutation carriers and

152 s was further validated in a cross-sectional cohort of 381 participants.

153 q analysis was carried out in an independent cohort of 43 ER+ HER2- and ER- HER2- primary breast tumo

154 GWAS in a separate cohort of 48 TIH patients and 2,922 controls from the 19

155 ng-term risk of SMNs in a well-characterized cohort of 5-year CCSs, with a particular focus on indivi

156 Overall, in our cohort of 6,016 patients, RBC transfusion was not associ

157 of the MAP17-SGLT2 interaction, we studied a cohort of 60 individuals with familial renal glucosuria.

158 ingapore Chinese Health Study, a prospective cohort of 63,257 Chinese men and women, aged 45-74 years

159 We studied a validation cohort of 98 heart recipients transplanted in Edmonton,

160 In this cohort of anticoagulated patients with AF, the sole pres

161 we represent drug response data for a large cohort of cell lines as a heterogeneous network.

162 ction Project in Industry) is a longitudinal cohort of employed men and women 18 to 74 years of age a

163 y out photosynthesis, plants require a large cohort of genes.

164 We recruited a multi-ethnic cohort of healthy volunteers (n = 91) and used their tis

165 iral (DAA) treatment policies in a real-life cohort of hepatitis C virus-infected policy 1, "universa

166 Nef genotype/phenotype analyses in a cohort of HIV-1 subtype C-infected patients (n = 168), t

167 -related (NLR-NAR) events and mortality in a cohort of human immunodeficiency virus (HIV)/hepatitis C

168 nd TBET) in umbilical cord DNA at birth in a cohort of infants from the Southampton Women's Survey (n

169 N with gene expression profiles (GEP) from a cohort of multiple myeloma (MM) patients and normal indi

170 nuary 1, 2011, to December 31, 2013, among a cohort of new patients prescribed dermatologic medicatio

171 significant improvement over a prescreening cohort of newborns with CF from 20 years before the cont

172 Conclusion In a large, population-based cohort of NHL survivors, preexisting cardiovascular cond

173 e mortality in a prospective and consecutive cohort of patients discharged from a previous acute hear

174 We compared a cohort of patients enrolled on a trial of reduced-intens

175 Analysis of a contemporary cohort of patients on dialysis revealed that mortality f

176 performed with a CZT SPECT camera in a large cohort of patients suspected of having coronary artery d

177 A single-center cohort of patients undergoing coronary or peripheral ang

178 Using a well-characterized cohort of patients with biopsy-proven NAFLD, this study

179 patients with ACOS identified in a real-life cohort of patients with COPD.

180 alence of clonal haemopoiesis in an external cohort of patients with lymphoma who were treated in a r

181 ne the effectiveness and safety of TMVR in a cohort of patients with native valve MR who were at high

182 ploratory retrospective study, we selected a cohort of patients with newly diagnosed or relapsed or r

183 natures of pathological diagnosis in a large cohort of patients with primary progressive aphasia (PPA

184 An incident cohort of patients with psoriasis aged 18 years and olde

185 validate the RD-OGI Score in an independent cohort of patients.

186 lth Initiative recruited a large prospective cohort of postmenopausal women between 1993 and 1998.

187 Among this cohort of racially diverse low-income patients hospitali

188 Among the entire cohort of SLK in this analysis, the cumulative differenc

189 tions of uveitis with visual impairment in a cohort of survivors of Ebola virus disease (EVD) in Monr

190 a from the Gulf Long-term Follow-up Study, a cohort of workers and volunteers involved in oil spill c

191 ee survival and overall survival in multiple cohorts of AML patients receiving treatment with the cyt

192 the Autism Genetic Resource Exchange (AGRE) cohorts of children with autism spectrum disorder (ASD),

193 validate PGS for QT interval in 2 real-world cohorts of European ancestry (EA) and African ancestry (

194 In two independent cohorts of melanoma patients treated with anti-CTLA4 and

195 in the prevalence of AD in population-based cohorts of patients followed longitudinally beyond child

196 amination [MMSE] </=25) using data from nine cohorts of patients with Parkinson's disease from North

197 o observational studies (n = 39211) included cohorts of persons treated for well-differentiated thyro

198 oteins were differentially expressed in each cohort, of which 65% were common to both.

199 of PTSD symptoms in two prospective military cohorts (one discovery and one replication data set).

200 events involving 102837 participants from 14 cohort or case-control studies conducted in North Americ

201 uding both identification and 4 verification cohorts (P < 2.19 x 10(-7)).

202 -varying when it was updated annually and as cohort participants moved.

203 In the different medical cohort, patients with double mutation had worse 3-year O

204 In this cohort, prenatal exposure to PFASs was associated with s

205 ing adulthood; 57% of affected women in this cohort presented during the postpartum period.

206 xis plus maraviroc to a contemporary control cohort receiving standard GVHD prophylaxis alone.

207 Following the procedure, the fat-grafted cohort reported similar breast satisfaction (AMD, -0.68;

208 system perspective, was applied to the PITER cohort (representative of Italian hepatitis C virus-infe

209 82.4% specificity in the Danish and Scottish cohorts, respectively.

210 Among the retrospective cohort, sensitivities ranged from 72% for the boronic ac

211 In a coronary artery disease cohort separate from volunteers of this study, compared

212 In the discovery cohort, sex-stratified analysis identified 2 additional

213 However, for one reconstitution cohort, some mice immunized with iDCpp65 showed GVH-like

214 This study is the first cohort-specific analysis to show that some children's PC

215 Cohort-specific crude and adjusted risk ratios for asthm

216 ndings may partly be attributable to several cohort-specific factors associated with breastfeeding an

217 he German Multicenter Allergy Study, a birth cohort started in 1990.

218 evention Study]; n=4910) and 2 observational cohort studies (CARDIA [Coronary Artery Risk Development

219 imarily into 2 broad categories: prospective cohort studies and interventional trials.

220 English-language cohort studies and randomized trials that compared diffe

221 nce and mortality, yet data from prospective cohort studies are limited.

222 udy uses data from the 2-phase, longitudinal cohort studies called Track and from a longitudinal coho

223 1,037 patients from two large US prospective cohort studies diagnosed from 1986 to 2013.

224 In data pooled from cohort studies in the literature, 8% of gene-positive pa

225 Future cohort studies should aim to confirm this possible effec

226 this study is to conduct a meta-analysis of cohort studies to assess pooled survival rates and progn

227 There were five cohort studies, one case series, and seven case reports.

228 The St Jude Lifetime Cohort Study (SJLIFE) retrospectively collected data on

229 This investigation was an observational cohort study at inpatient and ambulatory surgery setting

230 studies called Track and from a longitudinal cohort study called the Cooperative Huntington Observati

231 future lung cancer.Significance: This large cohort study firmly establishes an association between a

232 articipants with HIV from the Veterans Aging Cohort Study for a minimum of 3 years between Jan 1, 199

233 In this cohort study from Get With the Guidelines-Resuscitation,

234 We conducted a cohort study from January 2003 to March 2009 using the C

235 ldhood externalizing disorders, yet no large cohort study has investigated this association across a

236 Nationwide population-based retrospective cohort study in Sweden between January 1, 2005, and Dece

237 A prospective observational cohort study in the ICU of two tertiary hospitals betwee

238 We conducted a cohort study involving 1,325,563 pregnancies in women wh

239 We conducted a prospective cohort study of 189,793 men 40 y old or older during 199

240 Retrospective cohort study of 266,101 patients within the Veterans Aff

241 We performed a cohort study of 601 527 users of low-dose aspirin for pr

242 Prospective cohort study of adults undergoing LT for HCC between Jan

243 was a prospective observational multicentre cohort study of children from birth to 15 years of age u

244 he study was a longitudinal population-based cohort study of children with CP who were aged 18-60 mo

245 TB patients and controls, and a prospective cohort study of HIV-1-infected TB patients at risk of TB

246 This was a multicenter prospective cohort study of hospitals and private practices in Germa

247 This is a retrospective multi-institutional cohort study of patients undergoing 1 of 6 major electiv

248 A multinational retrospective cohort study of patients with BSI due to ESBL-E who rece

249 Longitudinal prospective cohort study over 5 years of follow-up.

250 alth Status) is an observational multicenter cohort study that enrolled 4062 patients aged >/=18 year

251 This registry-based cohort study used data from Danish nationwide registers

252 We conducted a population-based cohort study using Danish national registers.

253 We performed a retrospective cohort study using inpatient and outpatient Medicare cla

254 This single-center, retrospective cohort study was conducted from either September or Dece

255 The aim of this prospective clinical cohort study was to investigate the effect of obesity on

256 d 15 control participants from a prospective cohort study were included, which was approved by the lo

257 ent of Patients with Heart failure) clinical cohort study, 496 patients with acute HF were enrolled i

258 tutional review board-approved retrospective cohort study, an institutional database was searched for

259 In this cohort study, comorbidities influenced 1-year survival o

260 on In this relatively large population-based cohort study, hepatic triglyceride content was associate

261 In a large prospective cohort study, we evaluated the risk of breast cancer in

262 In a prospective, multicenter cohort study, we found that patients with irregular Z li

263 In this prospective cohort study, we performed multiregion whole-exome seque

264 This is a retrospective cohort study.

265 n among women enrolled in a 10-city Canadian cohort study.

266 Multicenter, prospective cohort study.

267 002 and 2015 and studied in an observational cohort study.

268 a replicating HDV infection in the Swiss HIV Cohort Study.

269 ,513 individuals of European ancestry from 4 cohorts suggested that methylation at cg08035323 (TAF1B-

270 gible 6.0% breakthrough reaction rate in the cohort that received 5-hour intravenous corticosteroid p

271 and asthma in children from 9 European birth cohorts that enrolled participants between 1996 and 2006

272 ylation in IIS (n = 60) and in 2 replication cohorts (the Manchester Asthma and Allergy Study [n = 30

273 In the study cohort, the mean (SD) age was 69.6 (12.1) years among 11

274 In the recent adult validation cohort, the model retained excellent performance as in t

275 In the retrospective cohort, the primary outcomes were treatment failure and

276 -wide association study results from the CTD cohorts, the LVOTD cohorts, and from the combined CTD an

277 In a single-institution cohort, these results suggest that NASH FibroSure may be

278 also may reflect biases from restricting the cohort to prematurity, because prematurity is an outcome

279 on was performed in propensity score-matched cohorts to investigate the outcomes.

280 ngs from two population-representative birth cohorts totaling more than 3,000 individuals and born 20

281 hese loci could be replicated in independent cohorts, underlining the role of epigenetic regulation o

282 The cohort underwent diagnostic assessment for LVNC by 4 sep

283 4-week post-treatment period, ascending dose cohorts underwent a further double-blind crossover, plac

284 vaccination and childhood asthma in a birth cohort using administrative databases, and we determined

285 d values were compared between angle surgery cohorts using Wilcoxon signed rank tests, Mann-Whitney U

286 Median age of the study cohort was 46 (interquartile range, 32-58).

287 T in patients with diabetes post-CABG in our cohort was high.

288 The cohort was randomly divided into a two thirds set (Nd =

289 The tumors represented in the patient cohort were mainly gastrointestinal (31.8%), brain (22.7

290 Patients in the expansion cohort were treated with 1.0 mg/kg luspatercept; dose ti

291 Patients in both cohorts were adults (>/=18 years in England, >/=16 years

292 Because the two cohorts were assessed using different instruments, we de

293 Expansion cohorts were initiated at 3.0 mg/kg in patients with mel

294 Risk factor differences between the cohorts were measured using the independent t test, Wald

295 Two natural history cohorts were studied including 168 longitudinal samples

296 The cost for the cohort, which included the cost of the test, subsequent

297 ject Viva, a prospective U.S.-based prebirth cohort with relatively low levels of lead exposure.

298 ongitudinal analyses were also performed for cohorts with available data.

299 by analyzing a large number of patients in 3 cohorts with different HIV disease progression phenotype

300 al and inferior parietal regions in the full cohort, with florbetapir positive/negative-associated va