ライフサイエンスコーパス: coil

1 g a 3-Tesla MRI system and a 32-channel head coil.

2 rmed using 3T apparatus with 32-channel head coil.

3 s-trans configuration and behave as a random coil.

4 aster, which we conclude is a compact random coil.

5 embly/disassembly of the fibrils into random coils.

6 ain tissues were obtained using microsurface coils.

7 change in either the terminal or penultimate coils.

8 nge from randomly folded to helically folded coils.

9 ith a magnetic nozzle consisting of multiple coils.

10 l Rfr coil and decreased toward the terminal coils.

11 ncture of pseudoaneurysm and embolization by coils.

12 d strands are significantly more robust than coils.

13 h that uses printing for fabricating receive coils.

14 ich contains an RIG film and a pair of small coils.

15 hat using Neutron Resonance Spin Echo (NRSE) coils.

16 three beta-sheets, seven alpha-helices, and coils.

17 intracranial aneurysms with the use hydrogel coils.

18 rowth in thickness leads to impossibly tight coiling.

19 mplex aneurysms that may not be suitable for coiling.

20 with high precision 3D actuation (e.g. voice coil, 1microm encoder resolution; stepper motors, 4micro

21 atients were treatment-naive with endorectal coil 3-T multiparametric MR imaging.

22 The functionally relevant random-coil-alpha-helix transition associated with Ca(2+) uptak

23 The conversion of the native random coil amyloid beta (Abeta) into amyloid fibers is thought

24 cal reactor consisting of a knitted reaction coil and a low-pressure mercury lamp.

25 slowest exchanging amides in the central Rfr coil and decreased toward the terminal coils.

26 blies, a mix of sequence-defined helix-sheet-coil and helix-sheet-helix architectures, are Nature-ins

27 ral advantages over the well-established eye coil and video-oculography methods.

28 29)Xe polarizer, custom-built radiofrequency coils, and an optimized gradient-echo MR imaging protoco

29 The devices combine subdermal magnetic coil antennas connected to microscale, injectable light-

30 Four coils are controlled separately to form an asymmetric ma

31 Secondly, an array of magnetic induction coils are designed to investigate the feasibility of a t

32 anges are measured from the remaining of the coils as receivers.

33 helix-(pi-sheet)-helix and helix-(pi-sheet)-coil assemblies occur without compromising intrinsic hel

34 ting post-acceleration of protons inside the coil at a rate 0.7 MeV/mm, which is comparable to the r

35 ter connected to a laser-lithographed saddle coil at the distal tip.

36 length all commensurate with highly flexible coil behaviour and unlike the previously characterised t

37 ngineering nanostructures assembled from rod-coil block copolymers.

38 res could be controlled by adjusting the rod-coil block ratios.

39 l paralog families, including small GTPases, coiled-bundle proteins, and proteins with beta-propeller

40 ol and acquires a more beta-sheet and random coil character in the nucleus.

41 sidue which are clearly distinct from random coil chemical shift correlations.

42 in the caspase recruitment domain, LATCH, or coiled coil can perturb intramolecular interactions medi

43 The coiled coil domain probably terminates near the critical

44 Here, we report coiled coil domain-containing 3 (CCDC3) as a new TAp63 t

45 contain intrinsically disordered regions and coiled coil domains.

46 The parallel architecture of the coiled coil has mechanistic implications for the arrange

47 The coiled coil has two spatially distinct conserved regions

48 recruitment domain (CARD), LATCH domain, and coiled coil have been shown to disrupt intramolecular ID

49 ate, in which the gp41 heptad repeat 1 (HR1) coiled coil is assembled at the trimer axis.

50 We find that the coiled coil linker and the attached histidine kinase dom

51 Although the coiled coil motif is highly conserved, it is uniquely su

52 interface involves interactions between the coiled coil of one WipA molecule and the phosphatase dom

53 ion of the transmembrane region and proximal coiled coil of the complex.

54 and the C-terminal domain, that 'clamps' the coiled coil of the plug, thus stabilising the activated

55 is interrupted between the transmembrane and coiled coil regions by a flexible Gly-rich linker.

56 hat destabilization of the membrane-proximal coiled coil restores function for defective spanin allel

57 ix was engineered to be locked in a parallel coiled coil state, mimicking the open state of the stato

58 mino acids within the core of the tetrameric coiled coil suggests that the coil may split into two in

59 main, revealing a 15-nm parallel homodimeric coiled coil.

60 ies of VP35 twist about each other to form a coiled coil.

61 mic region of the MotB dimer into a parallel coiled coil.

62 ngle beta-barrel domain and an extracellular coiled-coil ("passenger") domain.

63 designed DNA nanostructures in which protein coiled-coil (CC) dimers serve as building blocks for mod

64 -terminal Toll-interleukin receptor (TIR) or coiled-coil (CC) domain, a central nucleotide-binding (N

65 In a recent model, extended coiled-coil (CC) domains in the integrase subunits are p

66 We also found that the RING B-box coiled-coil (RBCC) domain in KAP1 and the proximal coupl

67 p a region of NEMO (residues 112-150) in its coiled-coil 1 domain that impedes the binding of linear

68 ng of linear (M1-linked) di-ubiquitin to its coiled-coil 2-leucine zipper ubiquitin binding domain.

69 hobic pocket of the catalytic core, with the coiled-coil aligned near the entrance of the substrate U

70 In this configuration, the P-CR coiled-coil alone is unlikely to regulate substrate acce

71 forms dimers and trimers, potentially via a coiled-coil alpha-helix.

72 The mutant NEMO lacked part of the CC1 coiled-coil and HLX2 helical domain.

73 FHA and catalytic domains contact the XRCC4 coiled-coil and LigIV BRCT repeats.

74 C-terminal domains (CTDs) associate with the coiled-coil and marked-box domains (CMs) of E2Fs.

75 peptide that self-assembles into a hexameric coiled-coil bundle and an Fc-binding Protein A fragment,

76 pulations via the formation of a dimeric E/K coiled-coil complex can be rationalized, the reasons for

77 e stemming from GSK180736A, a Rho-associated coiled-coil containing kinase 1 (ROCK1) inhibitor, the o

78 tomyosin cytoskeleton and the Rho-associated coiled-coil containing kinases.

79 and subsequent activation of Rho-associated, coiled-coil containing protein kinase (ROCK).

80 n of ERK1/2 and expression of Rho-associated coiled-coil containing protein kinase 1 (ROCK1).

81 TG-specific downstream target Rho-associated coiled-coil containing protein kinase 2, induced K19 exp

82 cally, these sequences are also replete with coiled-coil destabilizing residues.

83 The coiled-coil dimer is a widespread protein structural mot

84 The specificity of coiled-coil dimer pairing is mainly based on hydrophobic

85 ds likely alters interactions that stabilize coiled-coil dimers and thick filaments, causing disrupti

86 tides can be used to tune the stabilities of coiled-coil dimers over a wide range.

87 Tpm forms coiled-coil dimers, which assemble into a helical strand

88 This effect requires the N-terminus and coiled-coil domain (C-C) as mutations within the ORF1p C

89 modulating the interaction of the C-terminal coiled-coil domain (CC) and/or the leucine zipper (LZ) d

90 Structurally, Angptl4 contains an N-terminal coiled-coil domain (CCD) connected to a C-terminal fibri

91 ECN1 forms an antiparallel homodimer via its coiled-coil domain (CCD).

92 Its N-terminal coiled-coil domain (Num1CC) is proximal to mitochondria,

93 d by mechanistic studies that determined the coiled-coil domain 1 of EspD as a key compound-binding s

94 Rtt103 forms homodimers via its long coiled-coil domain and associates densely on the repetit

95 11 inhibitory domain and involves the CARD11 coiled-coil domain and two independent regions of HOIP.

96 10 forms oligomers in vitro, mediated by the coiled-coil domain at the N-terminal region of the prote

97 mains form an umbrella-like structure with a coiled-coil domain for the 'pole' and four helical 'ribs

98 Mutation of the coiled-coil domain in COP1, which prevents dimer formati

99 elopment and highlight the importance of the coiled-coil domain in this process.

100 Two antiparallel alpha-helices form a coiled-coil domain linked by a large extended connector

101 ovirus FP25K protein lacking this N-terminal coiled-coil domain localized predominantly to the nucleu

102 We show that the coiled-coil domain of AtZAR1 oligomerizes, and this doma

103 re, we describe tsf mutations that alter the coiled-coil domain of elongation factor Ts (EF-Ts) and c

104 t second-site suppressors clustered within a coiled-coil domain of Rz near the outer leaflet of the c

105 A conserved SPSP motif in a coiled-coil domain of SF1 is highly phosphorylated in pr

106 with a heterozygous missense mutation in the coiled-coil domain of STAT5B that presented with autoimm

107 in-of-function (GOF) mutations affecting the coiled-coil domain or the DNA-binding domain of signal t

108 The coiled-coil domain present on only some orthologues rend

109 with and without a C-terminal, alpha-helical coiled-coil domain respond similarly to the osmolality.

110 rotein (ORF1p), which contains an N-terminal coiled-coil domain responsible for cytoplasmic retention

111 ral protein cage by appending a C4-symmetric coiled-coil domain to the protein through a short, flexi

112 Novel variants affecting the conserved coiled-coil domain, so far exclusively found in fALS exo

113 rovide evidence that EURL interacts with the coiled-coil domain-containing protein CCDC85B so as to m

114 pendent of the E3 ligase activity, B-box, or coiled-coil domain.

115 that block spanin function are found within coiled-coil domains and the proline-rich region, motifs

116 be related to the underlying dynamics of the coiled-coil domains by application of a three-state "hop

117 Destabilization of the coiled-coil domains by site-directed mutagenesis increas

118 Coiled-coil domains can direct the assembly of protein b

119 xpanding the hydrophobic surface area of the coiled-coil domains through introduction of the bulky le

120 coating as well as early infection contained coiled-coil domains, and that these activities were gene

121 ng domain and the Mis18alpha-beta C-terminal coiled-coil domains.

122 rm a heterotetramer through their C-terminal coiled-coil domains.

123 ed from engineered proteins bearing terminal coiled-coil domains.

124 TRIOBP-1, finding it to possess two distinct coiled-coil domains: the central and C-terminal domains.

125 In the absence of coiled-coil formation, the C-terminal domain bound lipos

126 upstream regulators, LET-502 (Rho-associated coiled-coil forming kinase) and MEL-11 (a myosin-binding

127 Deletion of the anti-parallel coiled-coil forming region, but not the EKR-rich region

128 It demonstrates a parallel, coiled-coil heterodimer with a predominantly hydrophobic

129 g its TOG domains, which bind GTP-tubulin, a coiled-coil homodimerization domain, and a domain that i

130 hat EmMBD2/3 and EmGATAD2A/B proteins form a coiled-coil interaction known to be critical for the for

131 We conclude that an intact Mcm10 coiled-coil interaction surface is important for origin

132 ne microparticles, either through reversible coiled-coil interactions or through intermolecular isope

133 nsertions within the hydrophobic core of the coiled-coil interface.

134 ighly cooperative manner compatible with the coiled-coil intermediate state.

135 The coiled-coil is a docking site for sigma factors on RNA p

136 gy Family Member A (RhoA) and Rho-Associated Coiled-Coil Kinase 1 (ROCK1) activity downstream of Dish

137 coli with (GCwCCRho) and without (GCRho) the coiled-coil linker.

138 an unexpected regulatory concept executed by coiled-coil MDs to tightly control AAA+ chaperone activi

139 associate via head-to-head contacts between coiled-coil middle domains (MDs).

140 more complex nanostructures using additional coiled-coil modules, other protein parts, or templated s

141 tral oligomerization domain with a predicted coiled-coil motif.

142 among SS isoforms and contains several long coiled-coil motifs, typically implicated in protein-prot

143 Mi-1.2 encodes a coiled-coil nucleotide-binding leucine-rich repeat prote

144 e region including two linked genes encoding coiled-coil nucleotide-binding leucine-rich repeat prote

145 ication of a single, essential heptad in the coiled-coil of Spc110 and a minimal PACT domain.

146 c CC MBS in which amino acids 932-967 form a coiled-coil of two monomeric alpha-helices in parallel o

147 All regions encompass coiled-coil or alpha-helical structures, and three are i

148 nucleotide-binding domain and the C-terminal coiled-coil participate in the tetrameric assembly of th

149 The design is a trifaceted coiled-coil peptide helix, which self-assembles into ult

150 new class of crystalline materials based on coiled-coil peptides bearing unnatural metal-chelating t

151 l-ion-mediated strategy to assemble trimeric coiled-coil peptides in a head-to-tail fashion into line

152 orce manipulations in silico on a variety of coiled-coil protein fragments from myosin, chemotaxis re

153 hat mud, which encodes a microtubule-binding coiled-coil protein homologous to NuMA and LIN-5, is an

154 ere macromolecular assemblies are defined by coiled-coil protein interactions.

155 , we describe a new centriole component, the coiled-coil protein SAS-7, as a regulator of centriole d

156 at ZapA is encoded in an operon with a small coiled-coil protein we named ZauP.

157 One of these, transforming acidic coiled-coil proteins (TACC) 3, stabilizes EGFR on the ce

158 s2 interacts via Bbp1 with Spc29, one of the coiled-coil proteins forming the central plaque of the S

159 elle biogenesis are activated by the related coiled-coil proteins Multicilin and Gemc1.

160 Extended coiled-coil proteins of the Golgin family play prominent

161 ate that aggregates formed by association of coiled-coil proteins, in contrast to those linked by iso

162 A and CD93 bind to the same non-glycosylated coiled-coil region of MMRN2, but the binding of CD248 oc

163 ds to RNA polymerase and specifically to the coiled-coil region of the beta' subunit.

164 state to a heterodimeric state in which the coiled-coil region of WipA is engaged in a protein-prote

165 We identify a coiled-coil region within PxdA that is necessary and suf

166 Here we show that the coiled-coil region within the N-terminal portion of SS4

167 EH domain, the proline-rich region, and the coiled-coil region.

168 The presence of the coiled-coil replaced those phenomena with CL-dependent b

169 ed to a polyhedral nano-net held together by coiled-coil segments.

170 ear model, which should help improve current coiled-coil stability prediction algorithms.

171 ax=320A) than predicted for a fully extended coiled-coil structure (>500A).

172 s that reducing the flexibility of native Tm coiled-coil structure decreases the optimum interactions

173 eparated from the GT99 chain terminator by a coiled-coil structure that forms a molecular ruler to de

174 hairpin, the tip of which adopts a canonical coiled-coil structure.

175 ps comparable in length to its 50-nanometer coiled-coil subunits, indicative of a translocation mech

176 globular head of Uso1 binds to Ypt1 and its coiled-coil tail binds to the Golgi-associated SNARE, Se

177 ory vesicles by Ypt1-SW1(Sec4), the extended coiled-coil tail blocks docking to the plasma membrane.

178 s ppGpp, and its N-terminal region, like the coiled-coil tip of DksA, engages the active-site region

179 Non-associating pairs of coiled-coil units were strategically fused to generate t

180 Spindly's N-terminal coiled-coil uses distinct motifs to bind dynein light in

181 ation experiments identified the ArfGAP with coiled-coil, Ank repeat, and pleckstrin homology domain-

182 ur findings enable tuning the stabilities of coiled-coil-based building modules match a diverse range

183 ith or without inhibitors of Rho-associated, coiled-coil-containing protein kinase (ROCK), ERK, or PI

184 the DR5 signaling pathway or rho-associated, coiled-coil-containing protein kinase 1 (ROCK1) inhibiti

185 nd the alpha2 helices form a tight two-helix coiled-coil.

186 gma(F) by competing for binding to the beta' coiled-coil.

187 es its tandem BRCT repeats to bind the XRCC4 coiled-coil.

188 d by a helical plug connected to an extended coil-coiled platform spanning the bacterial periplasm.

189 including an N-terminal pleckstrin homology coiled-coiled extension (PHn-CC-Ex) and catalytic Dbl ho

190 Both contain coiled coils and a family-48 carbohydrate binding module

191 Coiled coils have frequently been used to construct nano

192 terotrimer from three pairs of heterodimeric coiled coils that mediate specific interactions while av

193 s the modularity of orthogonally interacting coiled coils to create a self-assembled protein nanotria

194 n amino acids 324-348, between its first two coiled coils, as essential for the formation of TRIOBP-1

195 er assembly distinct from classical trimeric coiled-coils in solution.

196 mechanical and kinetic properties of protein coiled-coils under mechanical nonequilibrium conditions

197 late the stabilities in an orthogonal set of coiled-coils without affecting their binding preferences

198 interaction mediated by interactions between coiled-coils, we hypothesize that WipA can thereby trans

199 s focal as MST, although these electrode and coil configurations affect differently specific brain re

200 chains and that some of the xyloglucan has a coiled conformation.

201 olded structure dominated by turn and random coil conformations.

202 ed with fibril surfaces in both extended and coiled conformations, but tethered configurations were n

203 vidence for xyloglucans in both extended and coiled conformations, yet xyloglucan chains were not dir

204 ryl content, and Rg, it increased the random coil content, surface hydrophobicity index (Ho), Guinier

205 hile aggregated beta-sheet, turns and random coil contents increased as temperature increased up to 6

206 The alpha-helix and random coil contents of the 600 MPa treated samples were 23.67%

207 ions are only indirectly incorporated in the coil design process, mainly through using the size of th

208 tors must diffuse through densely packed and coiled DNA to find their binding sites.

209 of the embedding of solvent molecules in the coiled double-string rope architecture, highly solvent s

210 A micro-heater composed of a copper-coil embedded in a polymer matrix helped in maintaining

211 This was followed by coil embolization of the HAA with improvement in symptom

212 Coil embolization was not possible due to the small cali

213 s successfully managed with a stent-assisted coil embolization.

214 n, the SP1 peptide exists in a dynamic helix-coil equilibrium, and that the addition of the maturatio

215 ature is more complicated with branching and coiling especially in tumors.

216 cal mapping reveals the formation of a stiff coiled filamentous structure underneath the capsid surfa

217 presents the first fully functional, printed coils for 1.5- and 3-T clinical scanners.

218 velopment of SN2 cooled MgB2 superconducting coils for MRI applications.

219 he deflection angle with different number of coils, forming a plasma structure similar to that observ

220 h-fidelity association with both helical and coil-forming synthetic polymers.

221 aled an alpha-helix with a loop connecting a coil fragment.

222 with 80 mT/m gradients and a 32-channel head coil from each of 3 concussive traumatic brain injury (c

223 ork to simulate PNS thresholds for realistic coil geometries to directly address PNS in the design pr

224 aturant concentrations, a mechanism known as coil-globule transition.

225 nt way to access highly contorted, helically coiled graphene nanoribbons.

226 espectively) occurred more frequently in the coil group.

227 ated by permanent magnets or superconducting coils has found applications in many fields such as mini

228 Three-dimensional T1-weighted dual-echo body-coil images were acquired three times.

229 n over the ipsilateral motor cortex with the coil in the posterior-anterior (PA) and anterior-posteri

230 Achieving a high packing density of coils in the lumen of aneurysms can decrease the risk of

231 on is stunted in samples containing a random coil, ionic, mucoadhesive thickener, the retention of so

232 ty of a tomographic approach, i.e., when one coil is driven by an alternating current as a transmitte

233 Firstly, a single inductive coil is placed on the top of a melting wood alloy to exa

234 Endovascular embolization with hydrogel coils is an effective and safe treatment method for cere

235 ated from the assembled novel stair-like and coil-like gold nanorod chiral metastructures, which is s

236 in solution the cortactin repeats resemble a coil-like intrinsically disordered protein.

237 rminal PPV blocks are adjacent to a flexible coil-like poly(norbornene) (PNB).

238 MRI and SWI using 3T MR and 32-channel head coil may provide useful information for preoperative gli

239 the tetrameric coiled coil suggests that the coil may split into two independent FtsQ-binding domains

240 luorinated amines through sequential reactor coils mediates diazoalkane formation and [3+2] cycloaddi

241 Endobronchial coils might have a role in the treatment of patients wit

242 t-unilateral ECT (25%) was comparable to cap coil MST (23%), demonstrating that ECT with a low curren

243 rtery aneurysms by clip ligation (n = 14) or coiling (n = 9).

244 small conformational changes that result in coiling of the hydrophobic C-terminus of the peptide on

245 Surgical clipping or endovascular coiling of UIAs did not show differences in morbidity at

246 hat THE REAL McCOIL consistently outperforms COIL on simulated data, particularly when most infection

247 and magnetic seizure therapy (MST) with cap coil on vertex.

248 ndels revealed that they predominantly adopt coil or disordered conformations, especially in proteins

249 and two residues (I476 and V482) were within coiled or beta-sheet regions in domain B distant to the

250 0.0%-29.8%)) patients allocated endovascular coiling (OR: 0.54 (0.13-1.90), p=0.40).

251 repetitive transcranial magnetic stimulation coil over a subject-specific dorsal lateral prefrontal c

252 -competent states, as compared with a random-coil polypeptide, may contribute to the slow in vitro fo

253 atients with PC underwent 3.0-T phased-array coil prostate magnetic resonance (MR) imaging, including

254 ducting human experiments after constructing coil prototypes.

255 certed motions of two preceding or following coils required for hydrogen bond disruption and amide hy

256 1.0%-12.1%)) patients allocated clipping and coiling, respectively.

257 Using a remote excitation-detection coil set, the changes in permeability are observed by sw

258 evealing a bundle of helices that may act as coiled springs to transmit the forces that open the chan

259 lly recognize the epitope region in a random coil state.

260 f residues adopting each of Helix, Sheet and Coil states, based on energy calculations using the C-Al

261 -Rtt103 association opens the compact random coil structure of the CTD, leading to a beads-on-a-strin

262 region of hIAPP, which starts from a random coil structure, evolves into ordered beta-sheet oligomer

263 lical content and formation of a more random coil structure, resulting in protein unfolding, inhibiti

264 Subsequently, this coiled structure disappears, the stiffness of the capsid

265 that may not be appropriate for endovascular coiling, such as wide-necked aneurysms located at branch

266 semble a continuous flow system from reactor coils, syringes, pumps, in-line liquid-liquid separators

267 rable to the results obtained from a similar coil target irradiated by a fs class laser at an order o

268 +/- 0.5 MeV obtained by irradiating helical coil targets with a few joules, sub-ps laser pulses at a

269 ed by employing a recently developed helical coil technique, which exploits the transient self-chargi

270 relies on dynamic helical systems as seen in coiling tendrils, spasmoneme springs, and the opening of

271 In the coil testing, an operating current as high as 200 A was

272 Finally, we model the marginal band coiling that occurs during the disk-to-sphere transition

273 ign of interdigitated electrodes and heating coil, the platform can be tailored to print various circ

274 bits a conformational transition from random coil to beta-sheet by changing the pH from acidic to alk

275 a conformational change from compact random coil to extended helical structure-the disappearance of

276 o that required for displacement of a single coil to facilitate amide hydrogen exchange in either the

277 in utilizing a dual-tuned, proton-phosphorus coil to minimize subject movement.

278 We randomly allocated clipping or coiling to patients with one or more 3-25 mm UIAs judged

279 s that it transforms from disordered (random coil) to alpha helical structure.

280 rmo-responsive polymers undergo a reversible coil-to-globule transition in water after which the chai

281 A random coil-to-helix transition mechanism has now been introduc

282 kbone and the resulting conformational helix-coil transition by time-resolved femtosecond/picosecond

283 sent a highly sensitive gradiometric receive-coil unit combined with a noise-matching network tailore

284 The coiling-up space structures are utilized to build desire

285 14-mm inner diameter of the BGA-12S gradient coil used in the BioSpec 70/20 and 94/20 series of small

286 g bronchoscopic techniques including valves, coils, vapour thermal ablation, and sclerosant agents ha

287 ious adverse events including pneumonia (20% coil vs 4.5% usual care) and pneumothorax (9.7% vs 0.6%,

288 analysis simulation, and then a demonstrator coil was empirically tested under the same conditions.

289 A previous method, COIL, was developed to estimate complexity of infection

290 Using field data we show that, unlike with COIL, we can distinguish epidemiologically relevant diff

291 Hydrogel coils were created to improve the chances of an effectiv

292 s-linkers can unbind, the marginal band will coil, whereas if the tension increases more slowly, the

293 both variants exist predominantly as random coils, whereas the oligomers form predominantly beta-she

294 ebral aneurysms were embolized with hydrogel coils, which expand in contact with blood.

295 oride with dibenzylamine in a single reactor coil with an in-line quench is presented.

296 AGE4 is more expanded and resembles a random coil with diminished affinity for AP-1.

297 sured PNS thresholds of two leg/arm solenoid coils with good agreement.

298 nced MR imaging, obtained without endorectal coil within 34 minutes 19 seconds.

299 ficiency was optimal via a circular receiver coil wrapped into a half-cylinder with a meandering tail

300 Stretching coiled yarns generated 250 watts per kilogram of peak el