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1 that insE is not essential for formation of cointegrates.
2 The requirement that both loxP sites in the cointegrate be packaged into a P1 head ensures that only
4 strains with natural integrase levels, only cointegrates between the two integron-bearing plasmids w
5 e transposition, i.e. adjacent deletions and cointegrates, by utilizing transposon ends on two sister
8 replicons may have evolved independently via cointegrate formation following a transposition event.
9 nd the extensive DNA replication involved in cointegrate formation suggests a remarkable plasticity i
10 Recombination between these repeats in the cointegrate generates the two smaller replicons which co
11 heir previously described sickle constructs (cointegrated human miniLCRalpha2 and miniLCRbeta(S)), mo
12 simple insertions during transposition, not cointegrates; (iii) insert downstream of the motif 5"-TT
14 antibody library and its target receptor are cointegrated into the plasma membranes of a population o
16 insertions by a variation of its established cointegrate mechanism in which, instead of a "nick, join
18 f the canonical correlations and variates in cointegrated models is extended from the first-order aut
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