ライフサイエンスコーパス: cold

1 tion and H2 O2 detoxification in response to cold.

2 d C species are defined agents of the common cold.

3 participants reported multiple exposures to cold.

4 c lipokines that activate BAT in response to cold.

5 in response to environmental stimuli such as cold.

6 %) discontinued scalp cooling due to feeling cold.

7 ggered painful hypersensitivity to innocuous cold.

8 city by rhinoviruses, which cause the common cold.

9 decreased to approximately 100 kcal/d during cold (102 +/- 47 kcal/d).

10 T imaging at rest and after exposure to mild cold (16 degrees C) temperature.

11 H2 S (150 muM NaSH) during prolonged (24-h) cold (4 degrees C) storage exhibited significantly (p <

12 th a nonbacterial AURI, including the common cold (53.4%), acute bronchitis (31.3%), acute sinusitis

13 proposed method compared to the conventional cold acetone precipitation method.

14 uggest a path for aromatic ring formation in cold acetylene-rich environments such as parts of the IS

15 ntified subjects with high and low levels of cold-activated BAT mass (high BAT, 96 +/- 37 g; low-BAT,

16 d during the cold stress condition to assess cold-activated BAT mass.

17 mined by a functional counterbalance between cold-activated TRPM8 channels and Shaker-like Kv1.1-1.2

18 es, CRLK1 and CRLK2, negatively modulate the cold activation of MPK3/6.

19 vely selected genes that would be related to cold adaptation in all species from our list.

20 In enzyme proteins, cold adaptation is attained through functional trade-off

21 ausible stepwise evolutionary trajectory for cold adaptations across Pooideae.

22 against clade 1 H5N1 viruses on an Ann Arbor cold-adapted (ca) backbone that induced long-term immune

23 ion modelling, to investigate how two common cold-adapted bird species, willow and rock ptarmigan (La

24 As found in cold-adapted enzymes, this phenotype likely compensates

25 ional component is attributed to sea breeze (cold air advection from ice-covered ocean onto adjacent

26 n High, which favors southward intrusions of cold air to East Asia and thus causes severe local cooli

27 llution episodes in winter during persistent cold-air pools (PCAPs).

28 We found that cold allodynia induced by chronic constriction injury (C

29 Together, our results suggest that cold allodynia is largely due to a functional downregula

30 Our results suggest that cold allodynia is linked to a reduction of IKD in both h

31 ld-type mice, oxaliplatin treatment produced cold allodynia that could be prevented by RgIA4.

32 We used CTXs as a surrogate model of cold allodynia to dissect the framework of cold allodyni

33 f cold allodynia to dissect the framework of cold allodynia-activated central pain pathways.

34 ke potassium current IKD in damage-triggered cold allodynia.

35 iently perturbs metastable states induced by cold and CD4Ms and increases their sensitivity to antibo

36 ar seas, where surface water is particularly cold and dense, it sinks to generate a tropic-ward flow

37 c, but the more extreme, sparsely vegetated, cold and dry High Arctic is generally considered to rema

38 ferent habitability conditions under extreme cold and dryness: the permafrost soil which is enriched

39 We projected excess mortality for cold and heat and their net change in 1990-2099 under ea

40 qH operates under stress conditions such as cold and high light and is photoprotective, as it reduce

41 cies inhabit hot and low-altitude as well as cold and high-altitude deserts.

42 oncentrations and pH were comparable between cold and hot brews.

43 ions of anthocyanins in the pomace, and both cold and hot maceration of fresh unblanched berries with

44 dium grind, medium roast/coarse grind) using cold and hot methods.

45 of land use patterns of riparian zone in the cold and hot spots found that land-use patterns had an i

46 ture, substrate oxidation, core temperature, cold and hunger scores, and plasma parameters were repea

47 TRPM family, member 8 (TRPM8) is the primary cold and menthol sensor in humans.

48 The cold and warm ischemic times improved significantly duri

49 ver, PpeS6PDH gene expression is affected by cold and water deficit stress.

50 es of disparate Pooideae to short-/long-term cold and with those previously known in the subtropical

51 We identified 318 lncRNAs responsive to cold and/or drought stress, which were typically co-expr

52 um accessions BdODDSOC2 is down-regulated by cold, and in one of the winter accessions in which this

53 the temperature-dependent susceptibility of cold- and warm-adapted amphibian species to the fungal p

54 performance gaps between pathogens and their cold- and warm-adapted hosts should occur at relatively

55 ts remaining in circulation as the amount of cold antibody was increased.

56 ic, the initial transcriptional responses to cold appear to be more conserved than later responses.

57 of brown adipose tissue before environmental cold are unknown.

58 while differing in virulence.IMPORTANCE Most colds are caused by rhinoviruses (RVs).

59 For the phantom scans, cold artifacts were visible on the PET image.

60 partitioned community changes into warm- and cold-associated assemblages and found that English bird

61 In contrast, the cold associations presented an attenuating trend, and th

62 t progress in atmospheric plasmas has led to cold atmospheric plasma (CAP) devices with ion temperatu

63 Cold atmospheric plasma (CAP), a novel promising anti-ca

64 control and precision that is achievable in cold-atom systems.

65 By placing cold atoms in optical cavities and inducing strong coupl

66 Our results demonstrate that microscopy of cold atoms in optical lattices can help us to understand

67 -destructive and lensless way to image ultra-cold atoms or molecules that can be further used for two

68 diabatic transportation of Rubidium ((87)Rb) cold atoms with minimal loss and heating with as few as

69 through cryptobiosis during six centuries of cold-based glacier burial in Antarctica, 2) after re-exp

70 gulation was evident, BdODDSOC2 responded to cold before BdVRN1.

71 effective heat transfer between a hot and a cold body to increase beyond the limits long known for b

72 atures <2 degrees C were detected in 4 of 19 cold boxes (21%) transporting vaccine from subnational d

73 The effects of hot and cold break industrial tomato paste production steps on p

74 f caffeine and 3-chlorogenic acid (3-CGA) in cold brew coffee were investigated by brewing four coffe

75 nstead of 10 to 24 hours outlined in typical cold brew methods.

76 order kinetics between 6 and 7 hours in all cold brew samples instead of 10 to 24 hours outlined in

77 We evaluated the cold chain in 23 health facilities and 36 outreach vacci

78 on offers the prospect of a solution to the "cold chain" problem for biological materials, in particu

79 included removal of all tOPV vials from the cold chain, placement in appropriate bags or containers,

80 which rely heavily on the maintenance of the cold chain, with potential improvement to the duration o

81 o have adequate stock of vaccines, essential cold-chain equipment, or proper documentation of vaccina

82 OCK reaction reagents can be lyophilized for cold-chain independence and long-term storage and be rea

83 Cold-chain independence and the potential for self-admin

84 We interviewed immunization and cold-chain staff, assessed equipment, and recorded tempe

85 Bangladesh has substantial cold-chain storage and transportation capacity after ina

86 successfully settled across western Eurasian cold-climate landscapes.

87 Angiosperm adaptations to seasonally cold climates have occurred multiple times independently

88 been linked to CO2 draw-down, but the severe cold climates of the Cryogenian have never been replicat

89 ange with an increase in the O3/HOx ratio in cold climates, the opposite of current expectations.

90 ure, higher density gas regime toward a very cold collision-free cluster regime that is dominated by

91 mprehensive examination of different hot and cold combined quenching/extraction approaches to extract

92 rowth under extremely oligotrophic, arid and cold conditions.

93 o, 2:1), to 68%, 67%, and 81%, respectively (cold contrast; 37-mm sphere diameter; ratio, 8:1).

94 To compile DMH maps for the autonomic cold defense and for the cold-seeking response to LPS, w

95 of yeast frataxin, a protein that undergoes cold denaturation above zero degrees, because the unfold

96 The large effect of PEG 20 on cold denaturation can be explained by a change in water

97 y, according to Privalov's interpretation of cold denaturation.

98 nd Plasma Wave Science instrument detected a cold, dense, and dynamic ionosphere at Saturn that inter

99 perature variation across the estuary during cold disturbances with different degrees of severity, in

100 cassava shoot apices and young leaves under cold, drought stress and control conditions.

101 m an early, warm, wet environment to today's cold, dry atmosphere.

102 mance at the anterior tract were found under cold/dry climate simulations.

103 We predict that higher occurrence of FTCs in cold ecosystems will select for large body size within s

104 nutrient transfer rates in soil food webs of cold ecosystems.

105 -linear, resulting in a steeper slope at the cold end of the temperature spectrum than at the warm en

106 herent neutron scattering in the thermal and cold energy regimes reveals which samples have a single-

107 ther lacustrine features of Gale formed in a cold environment by a mechanism yet to be determined, or

108 ng mammalian genes involved in adaptation to cold environment was designed, based on the intersection

109 s are well adapted to surviving in extremely cold environments.

110 ds of greatest risk to experience an extreme cold event varied among years.

111 outheastern United States endured an extreme cold event.

112 Analysis of rare heat and cold events for 2080-2099 relative to a base period of 1

113 in the rRPa of anaesthetized rats decreased cold-evoked BAT sympathetic nerve activity (SNA, nadirs:

114 zone (TNZ, 30 degrees C) for mice or during cold exposure (15 degrees C) in male wild-type mice.

115 the brain in this coupling process, we used cold exposure as an experimental paradigm because the sy

116 Here we report that cold exposure in mice triggers a metabolic program that

117 aracterize the initial metabolic response to cold exposure in multiple adipose tissue depots in mice.

118 anisms underlying homeostatic failure during cold exposure in this diverse group of ectotherms.

119 alterations in neurovascular function during cold exposure is clinically relevant.

120 cute painful sensory neuropathy on sustained cold exposure is not yet known, but individuals of Afric

121 rison, insulin clearance was not affected by cold exposure or phentolamine infusion.

122 mutant, resulting in rapid flowering without cold exposure, and the rapid-flowering rvr1 phenotype is

123 ic metabolism in adipose depots during acute cold exposure.

124 ases disproportionately during environmental cold exposure.

125 me severely hypothermic and succumb to acute cold exposure.

126 strate the distinct metabolism of BAT during cold exposure.

127 o Northern European winter cooling and daily cold extremes actually decrease.

128 d be tested experimentally in superfluids of cold fermionic atoms with laser field induced spin orbit

129 med when the beehives were moved back to the cold field, thereby suppressing brood rearing.

130 elated to extreme temperature (both heat and cold) for 15 cities in Northeast Asia (1972-2009).

131 ure, vesicles can be directed towards hot or cold, forming a highly concentrated region.

132 e for such studies because it cannot form in cold gas without suprathermal energy input, so its prese

133 n Inuit populations due to adaptation to the cold Greenland Arctic climate and to a protein-rich diet

134 ents is the availability of large numbers of cold ground state antihydrogen atoms.

135 se activity and on its ability to rescue the cold-growth inhibition of a Saccharomyces cerevisiae tgs

136 elt all Arctic sea ice within a few years, a cold halocline limits upward heat transport from the Atl

137 has been only limited success in developing cold-hardy cultivars.

138 The dramatic longevity-enhancing effect of cold has long been known in organisms ranging from inver

139 s human aortic endothelial cells (HAEC) from cold hypoxia/reoxygenation injury more effectively than

140 l-targeted H2 S donor, AP39, during in vitro cold hypoxic injury improved the protective capacity of

141 t most deaths found attributable to heat and cold in daily analyses were brought forward by at least

142 hanges decreased the sensitivity of HIV-1 to cold inactivation and ligands that require Env conformat

143 (20%) had inducible urticaria, most commonly cold induced.

144 find that in mice genetically lacking UCP1, cold-induced activation of metabolism triggers innate im

145 Both cold-induced and pharmacological thermogenic activation

146 f these postnatal beige adipocytes inhibited cold-induced beige adipocyte formation in adult mice.

147 brown fat development and thermogenesis and cold-induced beige fat formation.

148 mes, this phenotype likely compensates for a cold-induced decrease in kinetic rates-properties of rho

149 effect of large electrolytic DMH lesions on cold-induced hypothermia was due to suppressed thermogen

150 e changes, revealing a genetic mechanism for cold-induced longevity in this model organism.

151 more complex organisms the underpinnings of cold-induced longevity remain largely mysterious.

152 Mechanistically, cold-induced MT depolymerization experiments demonstrate

153 , providing a general model for this form of cold-induced pain.

154 We also built maps for cold-induced thermogenesis in unanesthetized rats and fo

155 Genetic ablation of Zbtb7b impaired cold-induced transcriptional remodeling in brown fat, re

156 esis, and enzymes were overproduced from the cold-inducible cspD2 promoter in the genetically tractab

157 Cold-inducible RNA-binding protein (CIRP), released into

158 Non-freezing cold injury develops after sustained exposure to cold te

159 Chronic non-freezing cold injury is a disabling neuropathic pain disorder due

160 s current induces cold sensitivity in former cold-insensitive neurons expressing low levels of TRPM8-

161 on symptoms in adults are fatigue, lethargy, cold intolerance, weight gain, constipation, change in v

162 The unprecedented resolution of cold-ion spectroscopy coupled with tandem MS may render

163 e detrimental clinical outcomes of prolonged cold IRI during RTx.

164 H2 S treatment mitigates cold IRI-associated renal injury via mitochondrial actio

165 Seasonal cold is causal, but, we contend, principally as an ecolo

166 ible donors, and is associated with a longer cold ischemia time and a potentially higher rejection ra

167 Mean kidney cold ischemia time was 10 +/- 3 and 50 +/- 15 hours, for

168 ties for planning surgery and also decreases cold ischemia time, potentially translating into a highe

169 kidney and liver donor risk indices, kidney cold ischemia, and inferior overall survival.

170 to 30 minutes of warm ischemia, 3.5 hours of cold ischemia, and then perfused with a humanized anti-C

171 and use of marginal livers, while minimizing cold ischemia.

172 slet isolations (donor age 41-59, BMI 26-38, cold ischemic time < 10 h).

173 point of retrieval, and so does not include cold ischemic time.

174 quency of poor ex vivo perfusion, had longer cold ischemic times, and were transplanted into older re

175 summer LSWT is variable, and is greater for cold lakes (e.g. high latitude and high altitude), which

176 Cold, low fertility growing conditions are often associa

177 and measurements for hot (>18 degrees C) and cold (<10 degrees C) hours with wind directions parallel

178 Chronic exposure to hot (>90th percentile), cold (<10th percentile), or mild (10th-90th percentile)

179 Cold maceration of frozen berries without enzyme additio

180 masses per year, require large reservoirs of cold molecular gas to be delivered to their cores, despi

181 ingtime patterns: warm tropical Atlantic and cold northeast Pacific sea surface temperatures (SSTs),

182 of (13)C in CO2) indicate that upwelling of cold, nutrient-rich water from near the seafloor accompa

183 l mutant lines, and for mechanical, heat and cold pain modalities.

184 al was interrupted by the Younger Dryas (YD) cold period.

185 ially its protracted duration and frequently cold phenomenology.

186 the NSD1 subtype of HNSC displays an 'immune cold' phenotype characterized by low infiltration of tum

187 The efficacy of cold plasma for inactivation of food-borne pathogens in

188 Understanding cold plasma interactions with food lipids and the critic

189 However, insights on cold plasma-food interactions in terms of quality effect

190 tor eluate directly to a vial containing the cold precursors THP-PSMA and sodium bicarbonate, with no

191 A physicochemical characteristic of the cold-pressed oil obtained from seeds of common beech (Fa

192 s, is at high level in comparison with other cold-pressed oils.

193 ifference was observed for other refined and cold-pressed vegetable oils.

194 tion procedure including solvent extraction, cold pressing and microwave pretreatment (MW) followed b

195 and microwave pretreatment (MW) followed by cold pressing on oil yield, physicochemical properties,

196 We show that the cold protease method provides a great reduction in gene

197 at uses a protease with high activity in the cold, purified from a psychrophilic microorganism.

198 Cold-regulated (COR) genes were also overrepresented amo

199 During this process, several cold-regulated (COR) proteins are accumulated in the cel

200 days after (RR = 1.23, 95% CI: 1.01, 1.49); cold-related admissions increased by 3.7% on high snowfa

201 This is equivalent to approximately 1,116 cold-related and approximately 1,019 hot-related excess

202 Lastly, transcript abundances indicated that cold-related signaling was also occurring.

203 K6 activities and has a positive role in the cold response.

204 However, studies investigating these complex cold responses are mostly conducted in controlled enviro

205 Genes with species-specific cold responses did not cluster in particular pathways no

206 The use of paired time-course data on cold-responsive gene expression in maize (Zea mays) and

207 While the majority of cold-responsive transcriptional regulation of conserved

208 tilocular morphology at the adult stage, but cold restored their beiging characteristics, a phenomeno

209 KEY MESSAGE: In maize seedlings, severe cold results in dysregulation of circadian pattern of ge

210 ooler, wetter climate known as the Antarctic Cold Reversal, revealing a cryospheric response to an An

211 on microstructure in the bulk of a sample of cold rolled aluminum, further deformed locally by a hard

212 ns promoted allocation of carbohydrates from cold roots to warm canopy and explained why starch level

213 5% lower early delivery risk during warm and cold season, respectively.

214 Cold seeking was represented by a site at the ventral bo

215 Our work identifies the neural substrate of cold-seeking behavior in systemic inflammation and expan

216 s for the autonomic cold defense and for the cold-seeking response to LPS, we studied rats with small

217 Sediments from three areas (two cold seeps with contrasting hydrocarbon composition and

218 ted to both an increase in the proportion of cold-sensitive neurons (CSNs) in DRGs contributing to th

219 d that the reduction of this current induces cold sensitivity in former cold-insensitive neurons expr

220 In primary somatosensory neurons, cold sensitivity is mainly determined by a functional co

221 pproach to isolate 9 suppressors of Deltahda cold sensitivity, and characterized the mechanistic basi

222 which these suppressors alleviated Deltahda cold sensitivity.

223 3 and the mechanisms by which mRNAs encoding cold shock proteins escape cooling-induced translational

224 lowing effective signals, including hypoxia, cold shock, heat shock, oxidative stress, exercise-induc

225 Although well-studied cold-shock protein A (CspA) family members are induced a

226 y herpes simplex viruses (HSV) cause painful cold sores or genital lesions in many people; less often

227 We find that this large-scale cold spell can be attributed to the concurrent super El

228 nt degrees of severity, including an extreme cold spell.

229 Specifically, we measured how extreme cold spells might interact with temporal variability in

230 Multiple lines of evidence show that cold stadials in the North Atlantic were accompanied by

231 Cold-start contributes a larger fraction of the total un

232 ology, emission certification standards, and cold-start on emissions.

233 ly significant differences in the effects of cold-start on GDIs and PFIs.

234 et tested on a chassis dynamometer using the cold-start unified cycle.

235 DH was evaluated with air and cold stimuli at 24 hours, 30, 90, and 180 days after tre

236 ex vivo kidney perfusion (NEVKP) with static cold storage (SCS) in a porcine model of DCD autotranspl

237 h HMP with those preserved using only static cold storage (SCS).

238 liver function compared with standard static cold storage (SCS).

239 respiration rate at 20 degrees C and during cold storage and subsequent shelf life, the main effect

240 ft function and survival following prolonged cold storage compared to UW solution.

241 ange ('Moro' and 'Tarocco') cultivars during cold storage have been investigated.

242 es (range, 122-530 minutes) after an initial cold storage period of 427 minutes (range, 222-877 minut

243 a murine OLT model with extended (20 hours) cold storage, as well as to analyze the requirement for

244 n, (18)F-FDG images were obtained during the cold stress condition to assess cold-activated BAT mass.

245 ring and whole-body thermal sensation during cold stress following the administration of a graded the

246 t portion of the vasoconstrictor response to cold stress in HTN.

247 in mediating the vasoconstrictor response to cold stress in hypertension.

248 In contrast to BAT, cold stress reduces blood flow and (18)F-FDG uptake in s

249 d plant development by light (PIF3, HY5) and cold stress response (CBF).

250 A role of trehalose and stachyose in cold stress signaling was also suggested.

251 ure to maintain core body temperature during cold stress, and reduced ability to survive starvation.

252 effect on the ability to acutely respond to cold stress, suggesting that LP-induced increases in FGF

253 K2 abundance in Daojiao for a time course of cold stress.

254 (tsv) mutant that is extremely sensitive to cold stress.

255 Rice is vulnerable to cold stress.

256 SP3 activated the expression of MdCBF3 under cold stress.

257 p. and their regulatory roles in response to cold stress.

258 ough uncoupled respiration to defend against cold stress.

259 irectional solidification upon printing on a cold substrate.

260 In February 2015, two cold surges traveling from north China caused a temporar

261 ugh their patterns of transmission and their cold symptoms are broadly similar to those of the major

262 ymptoms in asthmatic patients but suppressed cold symptoms in healthy subjects.

263 TRPM8 activation by CFA was potentiated by cold temperature involving the phosphatidylinositol 4,5-

264 o the sciatic nerve, and a decrease in their cold temperature threshold.

265 channels can be directly activated by hot or cold temperature with high sensitivity.

266 ng in brown fat, rendering mice sensitive to cold temperature, and diminished browning of inguinal wh

267 rapidly engaged upon exposure to dangerously cold temperature.

268 Collectively, we identify that cold temperatures and Adrb3 agonists activate distinct c

269 Mosses grow slowly, but cold temperatures minimize decomposition, facilitating m

270 ed hosts should occur at relatively warm and cold temperatures, respectively.

271 injury develops after sustained exposure to cold temperatures, resulting in tissue cooling but not f

272 with conserved transcriptional responses to cold tend to contain more micrococcal nuclease hypersens

273 Cold thermogenesis had the highest representation in the

274 to a reduction of IKD in both high-threshold cold thermoreceptors and nociceptors expressing TRPM8, p

275 factors, which spread across the locus after cold to enlarge the domain that contains H3K27me3.

276 nalogue scale (WBTS) ranging from 0 mm (very cold) to 200 mm (very hot) were all measured throughout.

277 gnaling, interactive pathways that influence cold tolerance and phenological development to optimize

278 Cold tolerance is important in defining the distribution

279 ance that likely serves as a universal plant cold tolerance mechanism.

280 ed in the adaptability of low-temperature of cold tolerance, fungal pathogenicity and specialized hos

281 to identify 17 genetic loci associated with cold tolerance.

282 elative traits were derived as indicators of cold-tolerance.

283 able resources for future studies to develop cold-tolerant maize varieties.

284 pecific binding assessment using a LC-MS/MS "cold tracer" method, we have identified 8 (PF-06445974)

285 ripe (TR) stages were immediately exposed to cold treatment (40 d, 0 degrees C) and an additional gro

286 Following cold treatment, the ripening behaviour of the three grou

287 , MPK4, and MPK6 are rapidly activated after cold treatment.

288 ted earlier to cease cycling altogether upon cold treatment.

289 cultures were less resistant to lysozyme and cold treatments than those of the wild-type strain.

290 9 CIndU subtypes: symptomatic dermographism, cold urticaria, delayed-pressure urticaria, solar urtica

291 odological validation was performed by using cold vapor atomic absorption spectroscopy.

292 as with two spectroscopic techniques, namely cold vapour atomic absorption spectroscopy (CV-AAS) and

293 induction, and susceptibility to the common cold virus.

294 spatial shift in the relative composition of cold- vs. warm-adapted species in a local assemblage [th

295 VEEV was weaponized during the Cold War and is recognized as a select agent.

296 nstatement to cocaine-seeking observed after cold water swim stress.

297 tion of lake trout (Salvelinus namaycush), a cold-water stenotherm, adjusted its use of habitat and e

298 Indices of annual heat and cold were used as predictors in regressions of annual mo

299 olor temperature (CCT) of 7863 K, producing "cold" white light.

300 (34% of the Carnot efficiency) with hot and cold working temperatures of 60 and 20 degrees C, respec