ライフサイエンスコーパス: cold shock

1 translational advantage under conditions of cold shock.

2 ge to hindwings, predation, desiccation, and cold shock.

3 robust transient maltose accumulation during cold shock.

4 d acquired freezing tolerance in response to cold shock.

5 g certain heat shock proteins are induced by cold shock.

6 e solutes were observed during both heat and cold shock.

7 mperatures (75-79 degrees C), but induced by cold shock.

8 i, is dramatically induced immediately after cold shock.

9 rrespondingly, CWP1 is down-regulated during cold shock.

10 r Ca2+ influx into the cytosol, e.g. heat or cold shock.

11 TIR1, TIR2, and TIR4 are also induced during cold shock.

12 during anaerobiosis and in some cases during cold shock.

13 F2, RbfA, and PNP-are known to be induced at cold shock.

14 e inhibitory effect in translation caused by cold shock.

15 ich is increased dramatically in response to cold shock.

16 sized to overcome the deleterious effects of cold shock.

17 able at 37 degrees C but was stabilized upon cold shock.

18 led with [35S]methionine at 30 min after the cold shock.

19 to be a major cause of CspA induction after cold shock.

20 37 degrees C but has a positive effect upon cold shock.

21 possible cell-cycle arrest in response to a cold shock.

22 owth lag acclimation phase immediately after cold shock.

23 tions of stress, such as stationary phase or cold shock.

24 also activated when cultures were exposed to cold shock.

25 expression of cloned genes upon induction by cold-shock.

26 sparing ATP consumption under conditions of cold-shock.

27 on of cspA, -B, -G, and -I was induced after cold-shock.

28 hock (30 min, 86 degrees C) and decreased by cold shock (30 min, 60 degrees C).

29 tream metY-rpsO operon genes was observed at cold shock, a condition to which the cell responds by ma

30 vity of CsdA is critical for its function in cold shock acclimation of cells and that the only protei

31 oteins are indispensable for survival during cold-shock acclimation and that they are probably also i

32 In E. coli, pnp autoregulation and cold shock adaptation are dependent upon RNase III cleav

33 d CsdA RNA helicase plays a critical role in cold shock adaptation.

34 g factor A (RbfA) from Escherichia coli is a cold-shock adaptation protein.

35 ays a negative role in cspA transcription in cold shock-adapted cells.

36 factor gene whose mRNA increased after mild cold shock and a second that responded to conditions of

37 Cold shock and anoxia upregulates a homologue of HU (Hlp

38 tinguishable from those reported for extreme cold shock and exposure to sodium tungstate and "molsin"

39 ity of S. aureus to respond to the stress of cold shock and increased resistance to CG 117-136.

40 en involved in the regulation of heat shock, cold shock and virulence genes, RNATs constitute an inte

41 truncated RNase R proteins we show that the cold-shock and S1 domains contribute to substrate bindin

42 ly, the nuclease domain alone, devoid of the cold-shock and S1 domains, is sufficient for RNase R to

43 entry into stationary phase, starvation, and cold shock, and a approximately 3-fold increase was seen

44 Induction of the stringent, cold shock, and heat shock responses dramatically stabil

45 o be involved in transcription regulation at cold shock, and S1 domain proteins, known to function in

46 ently repressed by oxygen and insensitive to cold shock, and the Cwp proteins are oppositely regulate

47 The induced activity is maximal after 2 h of cold shock, and then gradually declines but does not dis

48 slower, have reduced resistance to heat and cold shocks, and are more sensitive to oxidative stress

49 Here we identify cold shock as a novel trigger of SG assembly in yeast an

50 and trehalose synthesis are activated during cold shock (as well as during heat shock) and play an im

51 ransferase is induced more than 30-fold upon cold shock, as judged by assaying extracts of cells shif

52 ted evolutionary relationships between these cold-shock associated proteins.

53 sA protein from Thermotoga maritima, another cold-shock associated RNA-binding protein.

54 Following a cold shock at -10 degrees C for 1 h, expression of ScPCN

55 y of the rpsO-pnp promoters increased during cold shock at 10 degrees , resulting in a two-fold incre

56 In wild-type cells, following cold shock at 15 degrees C, the amount of free RbfA rema

57 with two functional promoters and show that cold shock at 26 degrees C for </= 0.5 h and the presenc

58 ime-course transcript profiling analysis for cold shock at 4 degrees C revealed that BMY8 (At4g17090)

59 ecrease in maltose accumulation during a 6-h cold shock at 4 degrees C.

60 periments for heat shock at 40 degrees C and cold shock at 5 degrees C showed that beta-amylase induc

61 the antibiotics at 37 degrees C, cells were cold shocked at 15 degrees C and labeled with [35S]methi

62 he normal scale of cspA mRNA induction after cold shock because a deletion of the stem-loop significa

63 dramatically increases the lag time after a cold shock before re-growth occurs.

64 gnesium and potassium concentrations, and to cold shock, but increasing the Ca(2+) in the media abrog

65 ine accumulation, stress conditions, such as cold shock, cause an increase in the level of spermidine

66 Cold shock causes eIF2alpha phosphorylation through the

67 RNase R in stationary phase or in cold-shocked cells is not acetylated, and thereby remain

68 expression is induced both in anaerobic and cold-shocked cells, so heme may also regulate DAN/TIR ex

69 significantly affected (P < or = 0.05) upon cold shock challenge, especially at 8 degrees C.

70 spC and CspE at physiological temperature or cold shock conditions and (ii) depends on the nucleic ac

71 on and eliminates CCA hypersensitivity under cold-shock conditions.

72 oplasmic stress [P3rpoH and htrA(degP )] and cold shock (cspA).

73 We have therefore termed this sequence cold shock cut box (CSC-box).

74 n's unusual pairing of RNA-binding motifs: a cold shock domain (CSD) and a pair of retroviral-type CC

75 Three cold shock domain (CSD) family members (YB-1, MSY2, and

76 The data indicate that the invariant cold shock domain (CSD) is necessary but not sufficient

77 Cold shock domain (CSD)-containing proteins such as CspA

78 omology with CspA (43% identity), termed the cold shock domain (CSD).

79 ted Akt binds to and phosphorylates the YB-1 cold shock domain at Ser102.

80 Mature RBP16 contains a cold shock domain at the N terminus and a C-terminal reg

81 we show that the RNA-binding protein CSDE1 (cold shock domain containing E1) is highly expressed in

82 interacting region of YB-1 is located in the cold shock domain of YB-1 and its immediate flanking seq

83 We show that tiRNA(Ala) binds the cold shock domain of YB-1 to activate these translationa

84 The presence of the cold shock domain places RBP16 as the first organellar m

85 cine rich C terminus in combination with the cold shock domain predicts that RBP16 will be involved i

86 B88/MdMYB124 act as direct regulators of the COLD SHOCK DOMAIN PROTEIN 3 (MdCSP3) and CIRCADIAN CLOCK

87 (tripartite motif-containing 28), and CSDA (cold shock domain protein A).

88 ombin and TGFbeta1 is the involvement of the cold shock domain protein YB-1, a potent repressor of SM

89 One of these proteins was identified as the cold shock domain RNA-binding protein Ypsilon Schachtel

90 ng protein A (DbpA) is a member of the human cold shock domain-containing protein superfamily, with k

91 The C terminus of eIF-5A contains a cold shock domain-like structure, similar to that presen

92 d that YB-1 directly binds to tiRNAs via its cold shock domain.

93 SP4), that possess an evolutionary conserved cold shock domain.

94 conserved region within the highly conserved cold-shock domain (CSD) of Y-box proteins.

95 confocal microscopy, we find that an intact cold-shock domain (CSD), containing two RNA-binding moti

96 ino acid sequence revealed the presence of a cold-shock domain at its N-terminus and a glycine- and a

97 etic analysis of these gene products and the cold-shock domain of human YB-1 protein reveals that the

98 we show that the moss Physcomitrella patens Cold-Shock Domain Protein 1 (PpCSP1) regulates reprogram

99 binding were found between PP1c and PPP1R7, cold-shock domain protein A (CSDA), and phosphodiesteras

100 -box binding protein 1 (YB-1) belongs to the cold-shock domain protein superfamily, one of the most e

101 Further analysis revealed that cold-shock domain-containing protein C2 (CSDC2), which p

102 We identified CARHSP1, a cold-shock domain-containing protein.

103 ulates translation in vitro, and mutation of cold shock domains 2 or 4 inhibited its translation acti

104 so observed that in vivo deletion of the two cold shock domains resulted in a loss of the ability of

105 RNA binding protein Unr, which contains five cold shock domains, has several specific roles in post-t

106 d RNA binding region in which the N-terminal cold shock domains, typical of most RNR family nucleases

107 The cold-shock domains appear to play a role in substrate re

108 ied as unr, an RNA-binding protein with five cold-shock domains.

109 Proteins containing "cold shock" domains belong to the most evolutionarily co

110 Under control conditions, cold shocks elicited a graded initial voltage transient,

111 Upon cold shock, Escherichia coli cell growth transiently sto

112 involvement in electrical responses to local cold shocks, exemplifying the role of the cytoskeleton i

113 chrotolerant Yersinia enterocolitica after a cold shock from 30 degrees C to 10 degrees C causes tran

114 elicase activity were able to complement the cold shock function of CsdA, suggesting that only the he

115 e R, an exonuclease, can also complement the cold shock function of CsdA.

116 horylase and RNase II, cannot complement the cold shock function of CsdA.

117 se R is essential for complementation of the cold shock function of CsdA.

118 of the ability of RNase R to complement the cold shock function of CsdA.

119 ich is cold inducible, cannot complement the cold shock function of PNPase.

120 nctions of CsdA play a role in its essential cold shock function or whether all do, and so far no pro

121 ains 1 and 2 of PNPase are important for its cold shock function, suggesting that the RNase activity

122 olymerization activity is dispensable in its cold shock function.

123 During this phase, translation of non-cold shock gene mRNAs is blocked, since they require col

124 eral stress response, biofilm formation, and cold shock genes highly expressed at 23 degrees C.

125 oduced at low temperature, the expression of cold shock genes is prolonged or derepressed.

126 al gene expression patterns of the classical cold shock genes varied, and only some of them, most not

127 lowing effective signals, including hypoxia, cold shock, heat shock, oxidative stress, exercise-induc

128 define transcriptome changes in response to cold shock, heat shock, stringent, and SOS response-indu

129 An acyltransferase induced by cold shock in Escherichia coli, designated LpxP, incorpo

130 howed increases in response to both heat and cold shock in this study were previously unlinked with t

131 nflux was investigated by the application of cold shocks in the presence of diverse actin disruptors

132 nificant increase in mRNA accumulation after cold-shock in defined rich medium.

133 han cspA, -B, -G, or -I transcripts after 1h cold-shock in either defined rich or defined minimal med

134 s and is dependent on YmdB production during cold shock; in contrast, stationary-phase regulation was

135 LAT sRNA1 and sRNA2 cooperated to inhibit cold shock-induced apoptosis in mouse neuroblastoma cell

136 sequences that were necessary for inhibiting cold shock-induced apoptosis or Notch1-mediated trans-ac

137 In conclusion, the cytoskeleton controls cold shock-induced Ca(2+) influx into SEs, leading to fo

138 ination, which is mediated by CspA and other cold shock-induced Csp proteins.

139 cantly destabilizes the mRNA and reduces the cold shock-induced cspA mRNA amount by approximately 50%

140 lpxL homologue, designated lpxP, encodes the cold shock-induced palmitoleoyl transferase.

141 Whereas cold shock-induced SGs take hours to form, they dissolve

142 TIMP-1-positive BL lines show resistance to cold-shock-induced apoptosis.

143 henicol, inhibitors of protein synthesis, on cold shock inducibility of these proteins.

144 h CspA, CspB, and CspG have been shown to be cold shock inducible and CspD has been shown to be stati

145 ucts and the cspI mRNA revealed that cspI is cold shock inducible.

146 d shock showed that in addition to the known cold shock-inducible genes, new genes such as the flagel

147 together, E. coli possesses a total of four cold shock-inducible proteins in the CspA family.

148 h not detected in our genetic screening, two cold shock-inducible proteins, namely, CspA, an RNA chap

149 e downshift from 37 to 15 degrees C, and its cold shock induction has been attributed to transcriptio

150 , Delta86-117, and Delta118-143) caused poor cold shock induction of beta-galactosidase.

151 erved cold box sequence had little effect on cold shock induction of beta-galactosidase.

152 In order to analyse the mechanism of cold shock induction of CspA, a major cold shock protein

153 ility has been shown to play a major role in cold shock induction of CspA.

154 Cold shock induction of cspB has been shown to be primar

155 r csps (cspA, cspB, cspG, and cspE) affected cold shock induction of mostly those genes that are tran

156 We propose that the cold-shock induction of nusA, infB, rbfA, and pnp occurs

157 Cold shock influenced metabolism far more profoundly tha

158 palmitoleoyl transferase under conditions of cold shock is attributed to greatly increased levels of

159 Its dramatic but transient induction upon cold shock is regulated at the level of transcription, m

160 ly altered the expression of 184 genes under cold shock; it was most stressed in hosts that only adju

161 In addition, cold shock leads to reduced mitochondrial function, ener

162 15 at one end of the gene cluster encoding a cold-shock-like protein that likely regulates the produc

163 A pnp mutant, upon cold shock, maintained a high level of CSPs even after 2

164 It is proposed that DB in cold shock mRNAs allows the formation of a stable initia

165 a Cold Box sequence conserved among several cold-shock mRNAs.

166 In one study, 64 million mutants of a cold-shock nucleus binding domain protein 1CSQ, with six

167 tion to heat shock, UV-C irradiation but not cold shock of monolayers prior to infection resulted in

168 Forisome dispersion was triggered by cold shocks of 4 degrees C or greater, which was indicat

169 When administered after cold shock or coinjected with heparin, dextran sulfate r

170 e carrier component and protect cells from a cold shock or energy depletion.

171 alternatively spliced LR transcripts inhibit cold shock or Fas ligand-induced apoptosis in mouse neur

172 ived Ca(2+) influx (occurring in response to cold shock or hypo-osmotic shock) is inhibited, and (ii)

173 hy females to environmental stresses such as cold shock or starvation activated the CaspaseTracker co

174 that activate the spindle checkpoint (i.e., cold shock or treatment with nocodazole, paclitaxel, or

175 The data support enhancing cold-shock pathways as potential protective therapies in

176 ving Xenopus eggs, exposure to nocodazole or cold shock prevents the addition of new plasma membrane

177 To evaluate the usefulness of cold-shock promoters for the production of proteolytical

178 Finally, cold-shock promoters showed unusual sigma(54)-dependence

179 The thermophilic Bacillus caldolyticus cold shock protein (Bc-Csp) differs from the mesophilic

180 degrees C causes transcription of the major cold shock protein (CSP) bicistronic gene cspA1/A2 to in

181 haea do not contain members of the bacterial cold shock protein (Csp) family, they all contain homolo

182 r verification, we have shown that the major cold shock protein (CspB) from Bacillus subtilis binds w

183 n-like structure, similar to that present in cold shock protein A (CspA).

184 n of two cell-free expressed model proteins, cold shock protein A and apomyoglobin (apoMb) in cell-fr

185 , consistent with previous results for CspA (cold shock protein A) and LysN (anticodon binding domain

186 tide-binding domain found in the prokaryotic cold shock protein and the translation initiation factor

187 iffers from the mesophilic Bacillus subtilis cold shock protein B (Bs-CspB) in 11 of the 66 residues.

188 , we investigate the mechanical unfolding of cold shock protein B (Csp), a showcase two-state folder,

189 ctrin R16 domain, Arc repressor, apo-azurin, cold shock protein B (cspB), C-terminal domain of riboso

190 The Escherichia coli cold shock protein CsdA is a member of the DEAD box fami

191 The Escherichia coli cold shock protein CspA family consists of nine proteins

192 ter of cspA, a gene that codes for the major cold shock protein CspA of E. coli, contains an extended

193 We report that the cold shock protein CspA of Staphylococcus aureus is requ

194 helicases (DBRHs) (CsdA, SrmB, RhlB) and the cold shock protein CspA, improves fitness of two indepen

195 The cold shock protein CspB from Bacillus subtilis binds T-b

196 spB-1, which represents residues 1-22 of the cold shock protein CspB from Bacillus subtilis, has been

197 -TB that has the same core as the mesophilic cold shock protein CspB-Bs from Bacillus subtilis, but o

198 dmCl concentration [C] for the protein L and cold shock protein CspTm compare well with experiments.

199 lt is correlated with thermostability in the cold shock protein family.

200 amino acid sequence identity with the major cold shock protein in E. coli, CspA, which has been show

201 The mRNA for CspA, a major cold shock protein in Escherichia coli, contains an unus

202 PNPase is a cold shock protein in S. coelicolor and the activity of

203 parison with 25 experimentally characterized cold shock protein mutants reveals an average correlatio

204 of four pairs of residues in CspA, the major cold shock protein of E. coli.

205 The relaxation kinetics of the major cold shock protein of Escherichia coli (CspA) in respons

206 -containing proteins such as CspA (the major cold shock protein of Escherichia coli) and its homologu

207 ism of cold shock induction of CspA, a major cold shock protein of Escherichia coli, deletion analysi

208 CspA, the major cold shock protein of Escherichia coli, is dramatically

209 s reduced to new basal levels, while the non-cold shock protein synthesis is resumed, resulting in ce

210 structural similarity to the RbfA protein, a cold shock protein that also specifically associates wit

211 ns of the compact unfolded state of a small cold shock protein under native conditions, but decrease

212 Finally, it is demonstrated that designed cold shock protein variants exhibit electrostatic proper

213 CspA, the major cold shock protein, binds RNA with low sequence specific

214 chaperone-like proteins, HdeA and HdeB; the cold shock protein, CspC; the YbgS (or homeobox protein)

215 Escherichia coli CspA, a major cold shock protein, is dramatically induced upon tempera

216 otective, mediated, at least in part, by the cold shock protein, RBM3.

217 slatome, including the upregulation of a new cold shock protein, RTN3, a reticulon protein implicated

218 vergent gene cluster that encodes a putative cold shock protein.

219 of the csp22 peptide derived from bacterial cold shock protein.

220 The major cold-shock protein (CspA) from Escherichia coli is a sin

221 Although well-studied cold-shock protein A (CspA) family members are induced a

222 g factor A) protein that was identified as a cold-shock protein and an auxiliary factor acting in the

223 For cold-shock protein and the SH3 domain, we accurately rep

224 The RNase R of A. hydrophila was a cold-shock protein and was required for bacterial growth

225 lem, we studied the dynamics of the unfolded cold-shock protein at different solvent viscosities and

226 s by repressing cspE at the LexA palindrome; cold-shock protein CspE enhances translation of rpoS mRN

227 /beta protein L and the 66-residue, all-beta cold-shock protein CspTm.

228 RbfA is also a cold-shock protein essential for Escherichia coli cells

229 single-molecule FRET measurements of a small cold-shock protein expose equilibrium collapse of the un

230 ion in the denatured state of CspTm, a small cold-shock protein from Thermotoga maritima, engineered

231 CspA was originally found as the major cold-shock protein in Escherichia coli, consisting of 70

232 CspA, the major cold-shock protein of Escherichia coli, has recently bee

233 CspA, the major cold-shock protein of Escherichia coli, is an RNA chaper

234 functional homologue of the Escherichia coli cold-shock protein pY.

235 Members of bacterial Csp (cold-shock protein) family promote cellular adaptation t

236 A cold-shock protein, CspA, was associated with the ion ne

237 ctor, RpoS, but was independent of the major cold-shock protein, CspA.

238 During this acclimation phase, specific cold shock proteins (CSPs) are highly induced.

239 Cold shock proteins (CSPs) enhance acclimatization of ba

240 Gly-rich, zinc finger-containing RBPs called cold shock proteins 1-4 (CSP1-CSP4), that possess an evo

241 Certain members of the CspA family of cold shock proteins act as nucleic acid chaperones: they

242 is of any other protein, indicating that the cold shock proteins are able to bypass the inhibitory ef

243 mologous pair of thermophilic and mesophilic cold shock proteins at high temperatures.

244 a protein (CspA) highly similar to the major cold shock proteins CspA and CspB of Escherichia coli an

245 by an increase in the synthesis of the major cold shock proteins CspA, CspB, and CspG.

246 3 and the mechanisms by which mRNAs encoding cold shock proteins escape cooling-induced translational

247 CspA, CspB, and CspG, the major cold shock proteins of Escherichia coli, are dramaticall

248 Three wild-type cold shock proteins taken from mesophilic, thermophilic,

249 Surprisingly, the synthesis of all these cold shock proteins was induced at a significantly high

250 and is characterized by induction of several cold shock proteins, including CsdA, during the acclimat

251 and is characterized by induction of several cold shock proteins, including polynucleotide phosphoryl

252 nse is characterized by induction of several cold shock proteins, including the DEAD-box helicase Csd

253 Mutational analyses confirmed that the small cold shock proteins, So1648 and So2787, are involved in

254 rature downshift, a group of proteins called cold shock proteins, such as CspA, CspB, and CsdA, are t

255 utational and sequence analysis of bacterial cold shock proteins, we designed a protein (CspB-TB) tha

256 Cold-shock proteins (Csps) are a family of small nucleic

257 The present results show that cold-shock proteins and S1 domains share not only the te

258 Cold-shock proteins are synthesized to overcome the dele

259 ling and hibernation also induce a number of cold-shock proteins in the brain, including the RNA bind

260 Cold-shock proteins of the CspA family help bacterial ce

261 Cold-shock proteins of the CspA family of Escherichia co

262 thought to be involved in RNA binding by the cold-shock proteins.

263 t CspE, a member of a family of RNA-binding "cold shock" proteins, and S1, an essential component of

264 al tags were altered in response to heat and cold shock, respectively.

265 the functional role of CspB in the bacterial cold shock response is discussed.

266 In Escherichia coli, the cold shock response is exerted upon a temperature change

267 In Escherichia coli, the cold shock response occurs when there is a temperature d

268 The cold shock response of Escherichia coli is elicited by d

269 eins, So1648 and So2787, are involved in the cold shock response of S. oneidensis.

270 nts a global transcriptional analysis of the cold shock response of Shewanella oneidensis MR-1 after

271 osome binding factor A (RbfA) is a bacterial cold shock response protein, required for an efficient p

272 (e.g. 15 degrees C), growth halts while the 'cold shock response' (CSR) genes are induced, after whic

273 wo powerful and antagonistic responses: the 'cold shock response' and the 'diving response'.

274 script units encode proteins involved in the cold-shock response and in Psl exopolysaccharide synthes

275 Comparison of heat- and cold-shock response patterns revealed that the majority

276 Both prokaryotes and eukaryotes exhibit a cold-shock response upon an abrupt temperature downshift

277 ity of heat-shock responses were shared with cold-shock responses, a previously unknown relationship.

278 vel, reveals relationships between heat- and cold-shock responses, and highlights the roles of known

279 Proteomic analysis of skin following heat or cold shock resulted in increased levels of HSP27, HSP60,

280 lex at low temperature in the absence of the cold shock ribosomal factors.

281 unique structure, with both zinc knuckle and cold shock RNA-binding domains, and were originally iden

282 or the exhaustive surface mutagenesis of the cold shock, RNase T1, and CheY proteins.

283 One hour after removal from cold shock, ScPCNA transcript levels were restored to th

284 ationalize certain termination-defective and cold shock-sensitive mutations in the nusA gene that hav

285 ced by both CD95-dependent and -independent (cold shock, serum deprivation, and gamma-radiation) path

286 profiling of Escherichia coli in response to cold shock showed that in addition to the known cold sho

287 Here we demonstrate that, during cold shock, sigma(B) contributes to adaptation in a grow

288 ck gene mRNAs is blocked, since they require cold shock-specific ribosomal factors for the formation

289 resses; for example, cspA, cspB and cspG for cold-shock stress and cspD for nutritional deprivation.

290 YmdB is transcriptionally activated by both cold-shock stress and the entry of cells into stationary

291 ate that E. coli is highly protected against cold-shock stress, as these CspA homologues existed at a

292 ection from damage induced by heat-shock and cold-shock stress.

293 ir proteins are expressed during hypoxia and cold shock, the Dan proteins are more stringently repres

294 icate that this mechanism does not require a cold shock to bring about the accumulation of CBF transc

295 ownshift from 37 degrees C to 16 degrees C ("cold shock"), trehalose levels in wild-type cells increa

296 The global response of S. oneidensis to cold shock was also characterized by the up-regulation o

297 sdA RNA helicase mutant, CSP expression upon cold shock was significantly prolonged, indicating that

298 090) was induced specifically in response to cold shock, while major induction was not observed for a

299 mitoleoyltransferase present in membranes of cold-shocked wild type cells but retained normal levels

300 lls, the pre-16S rRNA amount increased after cold shock with a concomitant reduction of the mature 16