ライフサイエンスコーパス: colony-stimulating factor 1

1 -dependent process when triggered ex vivo by colony stimulating factor-1.

2 elial growth factor, tissue factor (TF), and colony-stimulating factor 1.

3 yte-macrophage colony-stimulating factor and colony-stimulating factor-1.

4 ptors for platelet-derived growth factor and colony-stimulating factor-1.

5 IL-34, which was a known cytokine receptor, colony-stimulating factor 1 (also called macrophage colo

6 entiated into osteoclasts in the presence of colony stimulating factor-1 and receptor activator of NF

7 alpha(-/-) hematopoietic cells treated with colony-stimulating factor 1 and RANK ligand (RANKL), as

8 on of the putative tooth eruption molecules, colony-stimulating factor-1 and c-fos, both of which are

9 In vitro studies demonstrated that both colony-stimulating factor-1 and parathyroid hormone-rela

10 m the platelet-derived growth factor (PDGF), colony stimulating factor-1, and epidermal growth factor

11 ctivator of Nuclear factor-kappaB ligand and colony-stimulating factor-1, and decrease the expression

12 pression and proliferative responsiveness to colony-stimulating factor-1; and (c) elevated expression

13 Inhibition of TAM recruitment using an anti-colony-stimulating factor-1 antibody compromised the sur

14 stabilization, including macrophage-specific colony-stimulating factor 1, carbonic anhydrase 2, Bcl2,

15 Upon binding its ligand colony-stimulating factor-1 cFMS autophosphorylates, dim

16 etween interleukin 1 receptor antagonist and colony-stimulating factor 1, colony-stimulating factor 2

17 a stable complex with the chimeric receptor colony stimulating factor 1 (CSF)-Met and wild type DEP-

18 Colony stimulating factor 1 (CSF-1) produced by carcinom

19 Colony stimulating factor 1 (CSF-1) recruits tumor-infil

20 The cytokine colony stimulating factor-1 (CSF-1) acts as an important

21 how that microglia develop in mice that lack colony stimulating factor-1 (CSF-1) but are absent in CS

22 Macrophages depend on colony stimulating factor-1 (CSF-1) for differentiation

23 Colony stimulating factor-1 (CSF-1) is the primary growt

24 autophosphorylated Tyr559 in the JMD of the colony stimulating factor-1 (CSF-1) receptor (CSF-1R) bi

25 Colony stimulating factor-1 (Csf-1) receptor and its lig

26 acellular ligand binding domain of the human colony stimulating factor-1 (CSF-1) receptor to sequence

27 However, ATP or PAF together with colony stimulating factor-1 (CSF-1) synergistically stim

28 Colony stimulating factor-1 (CSF-1) was initially identi

29 dary events occur, such as the expression of colony stimulating factor-1 (CSF-1) which play a critica

30 ormyl-methionyl-leucyl-phenylalanine (FMLP), colony stimulating factor-1 (CSF-1), IgG-coated particle

31 n the gene for the macrophage growth factor, colony stimulating factor-1 (CSF-1), that are severely d

32 at the op locus which are totally devoid of colony stimulating factor-1 (CSF-1), the major growth fa

33 Early colony stimulating factor-1 (CSF-1)-induced changes in t

34 w tested the roles of Cdc42, Rac, and Rho in colony stimulating factor-1 (CSF-1)-induced macrophage m

35 he response of mouse BAC1.2F5 macrophages to colony stimulating factor-1 (CSF-1).

36 ar precursor cells under the control of both colony stimulating factor-1 (CSF-1, or M-CSF) and recept

37 ng signaling by the major macrophage mitogen colony-stimulating factor 1 (CSF-1) (also known as macro

38 s a signaling effector engaged by macrophage colony-stimulating factor 1 (CSF-1) and receptor activat

39 Removal of colony-stimulating factor 1 (CSF-1) causes macrophages t

40 ted with gamma interferon (IFN-gamma) DNA or colony-stimulating factor 1 (CSF-1) DNA prior to ocular

41 rapid osteoclast differentiation induced by colony-stimulating factor 1 (CSF-1) in Csf1-null toothle

42 of LCs in mice deficient in the receptor for colony-stimulating factor 1 (CSF-1) in steady-state cond

43 r tyrosine at codon 809 (Y809F) of the human colony-stimulating factor 1 (CSF-1) receptor (CSF-1R) im

44 Colony-stimulating factor 1 (CSF-1) receptor (CSF-1R, or

45 Activation of the human colony-stimulating factor 1 (CSF-1) receptor in NIH 3T3

46 The colony-stimulating factor 1 (CSF-1) receptor is a protei

47 arr virus (EBV) BARF1 gene encodes a soluble colony-stimulating factor 1 (CSF-1) receptor that neutra

48 Colony-stimulating factor 1 (CSF-1) regulates the surviv

49 s of either epidermal growth factor (EGF) or colony-stimulating factor 1 (CSF-1) stimulate collection

50 Colony-stimulating factor 1 (CSF-1) supports the prolife

51 other tyrosine kinases including, KIT, FLT3, colony-stimulating factor 1 (CSF-1), and RET, which are

52 The primary macrophage growth factor, colony-stimulating factor 1 (CSF-1), is expressed as a s

53 Colony-stimulating factor 1 (CSF-1), the cytokine acting

54 The effects of colony-stimulating factor 1 (CSF-1), the primary regulat

55 for the mononuclear phagocytic growth factor colony-stimulating factor 1 (CSF-1), we have demonstrate

56 phosphorylated at residue threonine 72 in a colony-stimulating factor 1 (CSF-1)- and mitogen-activat

57 clear that alloantibody can, in concert with colony-stimulating factor 1 (CSF-1)-dependent donor macr

58 ly suppresses OC differentiation by limiting colony-stimulating factor 1 (CSF-1)-dependent proliferat

59 A robust increase in colony-stimulating factor 1 (CSF-1)-directed motility wa

60 c1 (Q61L) or Cdc42 (Q61L) or stimulated with colony-stimulating factor 1 (CSF-1).

61 tants such as fractalkine (FKN) (CX3CL1) and colony-stimulating factor 1 (CSF-1).

62 Colony-stimulating factor-1 (CSF-1) accelerates tooth er

63 Colony-stimulating factor-1 (CSF-1) activation of the CS

64 Colony-stimulating factor-1 (CSF-1) and its receptor (CS

65 te to regulate specific genes in response to colony-stimulating factor-1 (CSF-1) and receptor activat

66 Two compounds, colony-stimulating factor-1 (CSF-1) and vitamin D-bindin

67 Expression cloning identified colony-stimulating factor-1 (CSF-1) as a ligand for BARF

68 radients of epidermal growth factor (EGF) or colony-stimulating factor-1 (CSF-1) can induce invasion

69 Disruption of SRC-1 also suppressed colony-stimulating factor-1 (CSF-1) expression and reduc

70 otic because of a frameshift mutation in the colony-stimulating factor-1 (CSF-1) gene (Csf1(tl)).

71 recessive null osteopetrotic mutation in the colony-stimulating factor-1 (CSF-1) gene, we show that C

72 Colony-stimulating factor-1 (CSF-1) induces expression o

73 Colony-stimulating factor-1 (CSF-1) is a hematopoietic g

74 Colony-stimulating factor-1 (CSF-1) is expressed by kidn

75 Because colony-stimulating factor-1 (CSF-1) is maximally express

76 In vitro, the combination of OPGL + colony-stimulating factor-1 (CSF-1) is required for opti

77 Blockade of colony-stimulating factor-1 (CSF-1) limits macrophage in

78 e investigated how costimulation by cAMP and colony-stimulating factor-1 (CSF-1) or interleukin-3 (IL

79 The colony-stimulating factor-1 (CSF-1) receptor is a protei

80 H3T3 fibroblasts co-expressing a form of the colony-stimulating factor-1 (CSF-1) receptor that is par

81 extracellular, ligand-binding domain of the colony-stimulating factor-1 (CSF-1) receptor to the tran

82 o-oncogene, which encodes for the macrophage colony-stimulating factor-1 (CSF-1) receptor, has been o

83 sponse of 3T3 cells to signaling through the colony-stimulating factor-1 (CSF-1) receptor.

84 Stimulation of macrophages with colony-stimulating factor-1 (CSF-1) results in the prote

85 Colony-stimulating factor-1 (CSF-1) stimulates motility

86 es, activation of WASPbs upon treatment with colony-stimulating factor-1 (CSF-1) was detected globall

87 The primary macrophage growth factor, colony-stimulating factor-1 (CSF-1), is homodimeric and

88 Colony-stimulating factor-1 (CSF-1), the primary regulat

89 Colony-stimulating factor-1 (CSF-1), the principal growt

90 2) mouse model of pancreatic islet cancer to colony-stimulating factor-1 (CSF-1)-deficient Csf1(op/op

91 Colony-stimulating factor-1 (CSF-1)-induced CSF-1 recept

92 gnal-regulated kinase (ERK) is necessary for colony-stimulating factor-1 (CSF-1)-mediated c-Myc expre

93 To ascertain the impact of SHP-1 on colony-stimulating factor-1 (CSF-1)-mediated survival an

94 Colony-stimulating factor-1 (CSF-1)-stimulated CSF-1 rec

95 responsive to stimulation by the macrophage colony-stimulating factor-1 (CSF-1).

96 d receptor activator of NF-kappaB ligand and colony-stimulating factor-1 (CSF-1).

97 the macrophage attractant and growth factor colony-stimulating factor-1 (CSF-1).

98 Colony-stimulating factor-1 (CSF-1)/macrophage colony-st

99 Colony-stimulating factor-1 (CSF-1, also known as macrop

100 Colony-stimulating-factor-1 (CSF-1) signaling through cF

101 The overexpression of the colony-stimulating factor-1(CSF-1) by epithelial ovarian

102 osine kinase inhibitor, blocks expression of colony stimulating factor 1 (CSF1) by a small subpopulat

103 Viral-mediated knockdown of neuronal colony stimulating factor 1 (CSF1) was used to modulate

104 Addition of recombinant colony stimulating factor 1 (Csf1), the specific ligand

105 Colony stimulating factor-1 (CSF1) and its receptor (CSF

106 tion has increased expression of xanthogenic Colony Stimulating Factor-1 (Csf1).

107 n neutralizing antibodies against macrophage colony-stimulating factor 1 (CSF1 or MCSF) or F4/80.

108 Colony-stimulating factor 1 (CSF1) and interleukin-34 (I

109 Production of macrophage colony-stimulating factor 1 (CSF1) by BCCs is required f

110 Previously we showed that activation of the colony-stimulating factor 1 (CSF1) gene by the chromatin

111 Expression of the colony-stimulating factor 1 (CSF1) gene is elevated in m

112 l nerve injury induced de novo expression of colony-stimulating factor 1 (CSF1) in injured sensory ne

113 Colony-stimulating factor 1 (CSF1) is known to promote o

114 et of inflammatory response genes, including colony-stimulating factor 1 (CSF1), a central regulator

115 ed, is characterised by an overexpression of colony-stimulating factor 1 (CSF1), and is usually cause

116 Patient data suggest that colony-stimulating factor-1 (CSF1) and its receptor (CSF

117 Colony-stimulating factor-1 (CSF1) is a major chemoattra

118 th muscle that can express varying levels of colony-stimulating factor-1 (CSF1), the expression of wh

119 DCs were absent in islets from colony stimulating factor-1 deficient mice and this abse

120 io lacked such projections, concomitant with Colony stimulating factor 1-dependent changes in xanthop

121 fibrosis, illustrating the critical role of colony-stimulating factor 1-dependent monocyte/macrophag

122 motif ligand 2 that stimulated migration of colony-stimulating factor 1-differentiated macrophages.

123 agy initiated by ULK1 is required for proper colony stimulating factor-1-driven differentiation of hu

124 In response to liver injury, colony-stimulating factor 1 drives early monocyte-mediat

125 ne marrow-derived macrophages that depend on colony-stimulating factor-1 for proliferation and surviv

126 t of DNA in the promoter region of the human colony-stimulating factor 1 gene into the left-handed Z-

127 y autosomal dominant mutations in the CSF1R (colony-stimulating factor 1) gene.

128 Increased expression of colony stimulating factor-1, insulin-like growth factor-

129 tyrosine kinase activator protein 1 (TKA-1); colony stimulating factor-1; insulin-like growth factor

130 nduced the tumor cells to express macrophage colony-stimulating factor 1 (M-CSF1 or CSF1) and other c

131 Conversely, incubation of colony-stimulating factor 1 macrophages with E2 increase

132 Depletion of immunosuppressive, colony stimulating factor 1 receptor (CSF-1R)-dependent

133 These analyses revealed that colony stimulating factor 1 receptor (Csf1r) gene expres

134 Mutations in the colony stimulating factor 1 receptor (CSF1R) have recent

135 lineage, based upon control elements of the colony stimulating factor 1 receptor (CSF1R) locus.

136 systemic deletion of macrophages expressing colony stimulating factor 1 receptor (CSF1R) was initiat

137 ng macrophages through its inhibition of the colony stimulating factor 1 receptor (CSF1R).

138 affecting the tyrosine kinase domain of the colony stimulating factor 1 receptor (encoded by CSF1R)

139 show that treatment with the pharmacological colony stimulating factor 1 receptor inhibitor PLX5622 s

140 with wild-type, but not macrophage-deficient colony stimulating factor 1 receptor mutant (Csf1r(-/-))

141 The colony stimulating factor-1 receptor (CSF-1R) affects mi

142 We found that PLX3397, an inhibitor of colony stimulating factor-1 receptor (CSF-1R), blocks gl

143 been found to be caused by mutations in the colony stimulating factor-1 receptor (CSF1R) gene.

144 Interestingly, colony stimulating factor-1 receptor (CSF1R) is signific

145 dministered a dietary inhibitor (PLX5622) of colony stimulating factor-1 receptor (CSF1R) to deplete

146 laced with the extracellular domain of human colony stimulating factor-1 receptor and expressed in en

147 nocytes/macrophages under the control of the colony stimulating factor-1 receptor promoter.

148 ynthase, the lack of CD45, CD133, and c-fms (colony stimulating factor-1 receptor).

149 e uptake in 3T3-L1 adipocytes expressing the colony stimulating factor-1 receptor/insulin receptor ch

150 tumour-to-tumour heterogeneity, response to colony-stimulating factor 1 receptor (CSF-1R) blockade a

151 scriptional events and signals downstream of colony-stimulating factor 1 receptor (CSF-1R) that contr

152 BIT, but not PIR-B, is in a complex with the colony-stimulating factor 1 receptor (CSF-1R), suggestin

153 on of macrophages induces phosphorylation of colony-stimulating factor 1 receptor (CSF-1R), which con

154 The colony-stimulating factor 1 receptor (CSF1R) is a key re

155 The receptor for macrophage colony-stimulating factor 1 receptor (CSF1R) is a produc

156 method revealed the presence of an activated colony-stimulating factor 1 receptor (CSF1R) kinase in t

157 y discovered that microglia are dependent on colony-stimulating factor 1 receptor (CSF1R) signaling f

158 croglia in the healthy adult mouse depend on colony-stimulating factor 1 receptor (CSF1R) signalling

159 utations in the protein kinase domain of the colony-stimulating factor 1 receptor (CSF1R) which is a

160 hanism is regulated by the activation of the colony-stimulating factor 1 receptor (CSF1R), thus provi

161 In contrast, colony-stimulating factor 1 receptor blockade diminished

162 acellular domain of VEGFR-2 with that of the colony-stimulating factor 1 receptor did not alleviate t

163 has revealed a novel mutation p.R782G in the Colony-Stimulating Factor 1 Receptor gene (CSF1R).

164 ncluding cellular interleukin-10, bcl-2, and colony-stimulating factor 1 receptor homologues and an e

165 hed in mice depleted of microglia by using a colony-stimulating factor 1 receptor inhibitor.

166 mary acini induced by chronic stimulation of colony-stimulating factor 1 receptor is coupled to endog

167 cked macrophage function in ID8 mice using a colony-stimulating factor 1 receptor kinase inhibitor (G

168 Increasing the expression of c-FMS (colony-stimulating factor 1 receptor) by introduction of

169 results of studies inhibiting the macrophage colony-stimulating factor 1 receptor,whereas the CD11b(+

170 Colony-stimulating factor-1 receptor (CSF-1R) is the maj

171 The colony-stimulating factor-1 receptor (CSF-1R) kinase reg

172 ession and can be targeted via inhibition of colony-stimulating factor-1 receptor (CSF-1R) to regress

173 tiation is mediated by signaling through the colony-stimulating factor-1 receptor (CSF-1R) which is n

174 laced with the extracellular domain of human colony-stimulating factor-1 receptor (CSF-1R), and these

175 IL-34 signaling via its cognate receptor, colony-stimulating factor-1 receptor (CSF-1R), is requir

176 osine phosphorylated after activation of the colony-stimulating factor-1 receptor (CSF-1R), which als

177 inhibiting either the myeloid cell receptors colony-stimulating factor-1 receptor (CSF1R) or chemokin

178 g in the E13.5 mouse fetal liver express the colony-stimulating factor-1 receptor (CSF1R), previously

179 nhibitors of the kinase domain of macrophage colony-stimulating factor-1 receptor (FMS).

180 We then used the colony-stimulating factor-1 receptor inhibitor PLX5622 t

181 overassemble myosin-IIA, and exhibit altered colony-stimulating factor-1 receptor signaling.

182 nsisting of the ligand-binding domain of the colony-stimulating factor-1 receptor spliced to the cyto

183 beta, IL-6, and TNFalpha; (b) loss of CD115 (colony-stimulating factor-1 receptor) expression and pro

184 The cFMS proto-oncogene encodes for the colony-stimulating factor-1 receptor, a receptor-tyrosin

185 ceptor, stem cell factor receptor (KIT), and colony-stimulating factor-1 receptor.

186 cells, we have created a chimeric receptor (colony-stimulating factor-1 receptor/insulin receptor ch

187 ne resorption were studied as the macrophage colony-stimulating factor-1-receptor activator of NF-kap

188 via the A(2A) receptor, inhibits macrophage colony-stimulating factor-1-receptor activator of NF-kap

189 er fracture with the pro-macrophage cytokine colony stimulating factor-1 significantly enhanced soft

190 ma membrane-spanning glycoprotein, pp130, in colony stimulating factor-1 stimulated or unstimulated m

191 ic macrophages, which also exhibit increased colony-stimulating factor-1-stimulated proliferation and

192 Differentiation, in response to RANKL and colony-stimulating factor 1, was evaluated while varying

193 ulating macrophages through the secretion of colony-stimulating factor-1 while the tumor-associated m