ライフサイエンスコーパス: combat

1 d a Th1/Th2 imbalance to be more effectively combated.

2 th their c-axis orientation tailored to best combat a selected failure mode.

3 a way of reducing cardiovascular disease and combating a leading cause of global morbidity and mortal

4 our ability to efficiently develop tools to combat AAT.

5 t drug combinations to increase efficacy and combat acquired resistance.

6 ing tumor-initiating cells (TIC) is vital to combat advanced-stage recurrent cancers.

7 ntial to formulate an effective strategy for combating aeolian desertification.

8 tential therapeutic benefits of autophagy in combating age-related disorders of the nervous system.

9 p develop realistic interventions capable of combatting age-related disease, and thus improving late-

10 tion is proposed as an important strategy to combat AI.

11 ionally designed immunotherapy strategies to combat Alzheimer's and related neurodegenerative disease

12 1 may represent a new therapeutic avenue for combating Alzheimer's disease.

13 mising avenue for developing therapeutics to combat AMD.

14 ch in turn jeopardizes the host's ability to combat and clear infections.

15 nd other unit variables, including suicide-, combat-, and unintentional injury-related unit deaths.

16 This intervention is an attractive option to combat anemia in India.

17 cines are important tools in the approach to combat antibiotic resistance.

18 ack Obama proposed a National Action Plan to Combat Antibiotic-Resistant Bacteria to curb the rise of

19 The National Action Plan for Combating Antibiotic-Resistant Bacteria set a goal of re

20 g infectious diseases, develop vaccines, and combat antimicrobial resistance, all with increased accu

21 te the appropriate use of antimicrobials and combat antimicrobial resistance, the workgroup provides

22 ave been proposed as "living antibiotics" to combat antimicrobially-resistant pathogens.

23 Studies have shown that combat-area deployment is associated with increases in a

24 censed therapeutics or vaccines available to combat arenavirus infection.

25 ide attempts within their unit increased for combat arms and other MOSs and for units of any size but

26 risk was significant whether soldiers had a combat arms MOS or other MOS (ORs, 1.4-2.3; P < .001) an

27 information for rational drug design to help combat ASFV in the future.

28 ell wall and host immunity is fundamental to combatting Aspergillus diseases.

29 phenomena among black flies (Simuliidae) and combating associated vector-borne diseases.

30 sents an interesting potential new target to combat atherosclerosis.

31 inally applied in astronomical telescopes to combat atmospheric aberrations, to improve image quality

32 axis might represent a potential avenue for combatting autoimmune diseases mediated by T reg cell dy

33 entification of small molecule inhibitors to combat B. burgdorferi infection.

34 y provide previously unidentified targets to combat bacterial biofilm formation.

35 ugh various approaches have been reported to combat bacterial infection by surface modifications to t

36 (Cam) is a broad-spectrum antibiotic used to combat bacterial infections in humans and animals.

37 igning strategies to mitigate resistance and combat bacterial infections.

38 ensing is considered a promising strategy to combat bacterial pathogenicity.

39 e Clitopilus passeckerianus are important in combatting bacterial infections in human and veterinary

40 hree types of surfaces have been designed to combat biofilm formation, while attempting to maintain o

41 accomplished in most patients with TBI from combat blast exposure and reveals high rates of visual f

42 evelopment of miRNA-targeted therapeutics to combat blinding diseases.

43 TRPV1 antagonists may provide a new means to combat bone problems associated with diabetes.

44 erties, is an emerging therapeutic target to combat cancer development, progression and drug resistan

45 has been widely considered as an approach to combat cancer progression and therapeutic resistance, bu

46 ngineered immune cells are being designed to combat cancer, focusing on how new synthetic biology too

47 apy (AuNRs-PPTT) is a promising strategy for combating cancer in which AuNRs absorb near-infrared lig

48 lay a central role in directly or indirectly combating cancer is a breakthrough that seems likely to

49 acrophages might represent a new strategy to combat cardiac arrhythmias.

50 ed miRs might become a promising strategy to combat cardiovascular ageing in a clinical setting.

51 Retrospective cohort study of US military combat casualties in Afghanistan between April 1, 2012,

52 Among medically evacuated US military combat causalities in Afghanistan, blood product transfu

53 nt of viable antivirulence therapeutics that combat cholera and, potentially, other forms of bacteria

54 er a basis for immunological intervention to combat chronic infection with T. gondii by targeting the

55 care (PHC) is being appreciated globally to combat clinical complexities underlying various metaboli

56 er high-occupancy vehicle (HOV) policies can combat congestion.

57 The remitted patients and combat controls did not differ on the behavioral or imag

58 tients, N=21; persistent patients, N=22; and combat controls, N=25) with repeated-measures (pre- and

59 uch knowledge is essential to understand and combat crop disease.

60 (n = 50) in the acute to subacute stage and combat-deployed control individuals (n = 44) in Afghanis

61 r evaluations, in contrast with only 5 of 44 combat-deployed controls (11%).

62 ents with concussive blast TBI compared with combat-deployed controls, whereas performance on cogniti

63 Across all trajectories, combat-deployed service members diverged from non-combat

64 t-deployed service members diverged from non-combat-deployed service members, even after a single dep

65 dy Mass Index of 30kg/m(2) or greater, prior combat deployments, and age 36 years or older was each a

66 dipose tissue may offer novel strategies for combating depression and anxiety.

67 (BAT) is an attractive therapeutic target to combat diabetes and obesity due to its ability to increa

68 xr and Shp inactivation may be beneficial to combat diet-induced obesity and uncover that hepatic SHP

69 ntified as potential therapeutic targets for combating diet-induced obesity and metabolic disease.

70 proach to develop more effective vaccines to combat disease caused by this important respiratory path

71 ARE/Nrf2 can be attenuated through a SFN, to combat diseases associated with aging.

72 tics, diagnostics, and vaccine candidates to combat diseases caused by Bp and Bm.Melioidosis and glan

73 have also been used extensively by humans to combat diseases.

74 which scientists can play a valuable role to combat disinformation.

75 is, thus, an interesting target molecule to combat doxorubicin-induced cardiotoxicity.

76 receptor is very effective in helping plants combat drought stress.

77 ing and interventions are highly required to combat drug abuse.

78 is a great need to discover new compounds to combat drug resistance in parasitic nematodes.

79 To combat drug resistance, new chemical entities are urgent

80 (UPS), therefore, is an attractive avenue to combat drug resistance.

81 ppears to be a logical and valid approach to combating drug resistance.

82 evelopment of pure theranostic nanodrugs for combating drug-resistant bacterial infections.

83 sion, Body Mass Index, the presence of prior combat duty and selected control variables and the outco

84 tion caused by all species of schistosome to combat emerging resistance to current therapy.

85 eutic and/or prophylactic vaccine vectors to combat emerging viral diseases.

86 for a repurposed, host-targeted approach to combat emerging viruses.

87 ential processes is a successful strategy to combat enemies.

88 physical, chemical, and immune mechanisms to combat environmental stress.

89 Vaccination remains the best option to combat equine herpesvirus 1 (EHV-1) infection, and sever

90 The NIH is combating errors by requiring investigators to follow ne

91 n of these systems has now been exploited to combat eukaryotic viruses throughout the viral life cycl

92 perimental manipulation, can be effective in combating even the most serious of infections by E. coli

93 of post-traumatic stress disorder (PTSD) in combat-exposed soldiers.

94 -related mental stress using virtual reality combat exposure (VRCE) and non-combat related stress usi

95 shows heterogeneous patterns of development, combat exposure is uniformly associated with poor mental

96 d on the models, nearly 90% of those without combat exposure remained resilient over the 10-year peri

97 , as well as in individuals with and without combat exposure, respectively.

98 deployed military personnel with and without combat exposure, we used data from a population-based re

99 year period, compared with 80% of those with combat exposure.

100 s into adipocytes, pointing to a strategy to combat fatty degeneration of skeletal muscle.

101 ies can explain existing strategies known to combat fractional killing and facilitate the design of n

102 he generation of novel vaccine modalities to combat Gram-positive bacterial infections.

103 to overcome these limitations as well as to combat growing resistance to the class.

104 tially promising novel therapeutic target to combat H. pylori-associated diseases.

105 the design of novel, epigenetic therapies to combat HBV infection and poor prognosis HBV-associated l

106 for designing new therapeutic strategies to combat HDM allergy.

107 of the ISR emerges as a promising avenue to combat head trauma-induced chronic cognitive deficits.

108 of therapeutic and prevention strategies to combat herpesviral infection and pathogenesis.

109 ccines (LAVs) will represent a major step to combat HFAs.

110 ramework for understanding, quantifying, and combating HGT within the microbiome and the emergence of

111 will help to identify novel drug targets to combat HIV-1 infection.IMPORTANCE HIV-1 needs to overcom

112 of antibody-based vaccines and therapies for combating HIV-1 infection.

113 analysis, so further research is required to combat honey adulteration and mislabeling.

114 odes numerous proteins that are dedicated to combat host antiviral responses.

115 the host, disseminate to other tissues, and combat host copper bombardment mechanisms that would oth

116 zyme could be a new therapeutic approach for combating HPV spread and disease.

117 lation of hDBR1 as an effective strategy for combating human cancer.

118 AURKA as a potential therapeutic target for combatting hyperactive AURKA-driven NSCLCs.

119 al implantations, there is an urgent need to combat implant-associated infection.

120 Interventions to combat implicit bias will be required, and structural in

121 ts prevalence in the soldiers returning from combat in Iraq and Afghanistan.

122 y and 33 healthy controls who also served in combat in Vietnam but had no history of brain injury.

123 Recent efforts to combat increasing greenhouse gas emissions include their

124 drinking water is a human right, crucial to combat inequalities, reduce poverty and allow sustainabl

125 enhance efferocytosis could be harnessed to combat infection and chronic inflammatory conditions.

126 ung inflammation but also reduced ability to combat infection by the nematode Brugia malayi.

127 MPORTANCE Measures taken by the host cell to combat infection drive the evolution of pathogens to cou

128 acteriovorus are naturally antibacterial and combat infections by traversing, modifying and finally d

129 n urgent need for therapeutic development to combat infections caused by Rift Valley fever virus (RVF

130 matory response to infections, and they help combat infections through diverse mechanisms.

131 To combat infections, amphiphilic small molecules have been

132 ism that could affect a patient's ability to combat infections.

133 teria, and manipulation of the microbiome to combat infections.

134 tiple subcellular trafficking circuitries to combat infections.

135 fostered hope that new ways will be found to combat infectious diseases that have proven refractory t

136 n expression of genes, the products of which combat infectious microorganisms, initiate repair, and r

137 ase TBK1 initiates inflammatory responses to combat infectious pathogens by driving production of typ

138 cesses, which has important implications for combatting infectious diseases and for stably establishi

139 New measures to combat influenza are needed, but before they can be deve

140 he mainstay of the public health strategy to combat influenza.

141 ry of Defense Gates reduced the time between combat injury and receiving definitive care.

142 or developing new classes of insecticides to combat insecticide-resistant mosquitoes and the transmis

143 pocyte fate, and suggest a novel strategy to combat insulin resistance in obesity.

144 t fine-tune macrophage effector functions to combat intracellular pathogens and reduce inflammatory t

145 , enabling tunable CRISPR immune response to combat invader evolution.

146 a requirement for activation to effectively combat invading pathogens.

147 ns may be a feasible therapeutic approach to combat IRI.

148 elated TRP channels, and thus can be used to combat isoforms of pain and inflammation in-vivo that in

149 (hypoxia) and employ a conserved pathway to combat its effects.

150 ants is crucial to support CD8(+) T cells in combating JCV infection of the CNS.

151 nd can elicit functional immunity capable of combating live bacterial infections in a mouse model.

152 t PfHDP could be an important drug target to combat malaria.

153 firms its nutritive quality that can help to combat malnutrition.

154 do not require KatG activation is crucial to combat MDR TB.

155 sign of highly effective subunit vaccines to combat MERS-CoV and other life-threatening viruses.

156 dical countermeasures (MCM) are available to combat MERS-CoV infections.

157 strategies to enhance energy expenditure and combat metabolic disease.

158 s important to predict patient prognosis and combat metastasis.

159 rigenesis signatures in future might help to combat metastasis.

160 at Skp2 targeting is a promising approach to combat metastatic CRPC by targeting Twist and CSCs.

161 mmune cells that respond to inflammation and combat microbial transgression.

162 the search for more effective treatments to combat mRCC.

163 ecies-specific therapeutics in the effort to combat multidrug resistance.

164 to discover new antibiotics or strategies to combat multidrug resistant bacteria, especially Gram-neg

165 e is a pressing need for new therapeutics to combat multidrug- and carbapenem-resistant bacterial pat

166 e, a second-line antitubercular drug used to combat multidrug-resistant Mtb strains.

167 cells may provide new treatment options for combating nasal polyposis.

168 To combat Neisseria meningitidis serogroup A epidemics in t

169 need to be produced at frequent intervals to combat newly arising influenza virus strains, so that a

170 sue (BAT) has emerged as a potential tool to combat obesity and associated metabolic complications.

171 Thermogenesis from these adipocytes can combat obesity and diabetes, encouraging investigation o

172 xpenditure (EE) is an attractive strategy to combat obesity and diabetes.

173 s and exercise are the preferred approach to combat obesity and reduce its associated health risks.

174 tial novel drug targets to better define and combat obesity and related diseases.

175 apable of activating inducible BAT (iBAT) to combat obesity.

176 lling may be a novel therapeutic approach to combat obesity.

177 lead to the development of new therapies to combat obesity.

178 ts the alternating diet as a new strategy in combating obesity and metabolic diseases.

179 time-tested, yet underexploited approach to combat or prevent drug resistance.

180 are occasionally co-opted by their hosts to combat other viruses.

181 factor NRF2 is the major line of defense to combat oxidative or electrophilic insults.

182 on of NADPH to levels that are sufficient to combat oxidative stress in cancer cells.

183 new opportunities for novel therapeutics to combat pathogens.

184 ortantly, among the various oxidative stress combat players in E. coli, ubiquinone acts as the cell's

185 immunisation provides a robust strategy for combating pneumococcal antimicrobial resistance.

186 To combat pollution, improved programs of public health and

187 oreceptor (alpha1AR) antagonist prazosin for combat posttraumatic stress disorder (PTSD) in 67 active

188 mechanisms of action are urgently needed to combat potential pandemics, emerging viruses, and consta

189 that a complex proteostasis network actively combats protein aggregation and that such an efficient s

190 olera, utilizes distinct genetic programs to combat reactive oxygen species (ROS) in aquatic environm

191 ing that chitosan can be used to effectively combat recalcitrant bladder infections without causing l

192 nd 1960s have been relatively ineffective in combating recent epidemics.

193 eactivity during both combat-related and non-combat related mental stress, impaired sympathetic and c

194 rtual reality combat exposure (VRCE) and non-combat related stress using mental arithmetic (MA).

195 SNS and haemodynamic reactivity during both combat-related and non-combat related mental stress, imp

196 s well as during two types of mental stress: combat-related mental stress using virtual reality comba

197 tional outcomes among veterans who sustained combat-related mild TBI.

198 unctional outcomes of veterans who sustained combat-related mild traumatic brain injury (TBI) are ass

199 Fourteen otherwise healthy Veterans with combat-related PTSD were compared with 14 matched Contro

200 up periods, and the inability to account for combat-related trauma.

201 hing interpersonal (IP)-related traumas from combat-related traumas.

202 Combat-related words and generically negative words were

203 ffers an alternative therapeutic strategy to combat resistance associated with conventional anti-VEGF

204 s part of therapeutic strategies to delay or combat resistance.

205 , and discuss new strategies for effectively combatting resistance, optimizing treatment and advancin

206 Our strategy to combat resistant bacteria consisted of targeting the Gyr

207 To address if fleas combat rickettsial infection, we characterized the cat f

208 ypothesized catalase may play a large stress-combating role independent of its classical catalytic on

209 cal trials and also additional strategies to combat roles of EZH2 in cancer.

210 iotics and strategies are urgently needed to combat S. aureus associated infections.

211 Exercise is the only known strategy to combat sarcopenia and this is largely mediated through i

212 ndustry partnership in pioneering studies to combat serious bacterial infections.

213 wide use of extra virgin olive oil (EVOO) to combat several diseases, the antidiabetic and anti-choli

214 ginal exposure to RNA viruses is required to combat sexual transmission of this class of pathogens.

215 ay thus represent an interesting strategy to combat skeletal muscle loss and weakness in stroke patie

216 ghlighting the need for increased efforts to combat subtler forms of gender bias in scholarly publish

217 ment as well as an instance of interspecific combat; such aggression is a social feature of modern an

218 hose critically injured initially treated by combat support hospitals (9.1% [48 of 530] vs 15.7% [86

219 guide its further development to potentially combat TB in HIV-endemic areas.

220 to develop novel antimicrobial therapies to combat TB.

221 ns targeting general brain health to jointly combat the disease.

222 d rare variants to develop new approaches to combat the disease.

223 Collaborative efforts are urgently needed to combat the emerging hypertension burden in low- and midd

224 ) has mobilised efforts among 180 parties to combat the global tobacco epidemic.

225 g salty taste will help inform strategies to combat the health problems associated with NaCl overcons

226 There is an urgent need for a vaccine to combat the hepatitis C virus (HCV) pandemic, and inducti

227 evated phospho-Akt levels to therapeutically combat the heterogeneity of EGFR tyrosine kinase inhibit

228 in the development of effective vaccines to combat the highly sophisticated evasion mechanisms of pa

229 the development of a novel class of drugs to combat the hitherto intractable disorder of chronic asth

230 make rolofylline an interesting candidate to combat the hypometabolism and neuronal dysfunction assoc

231 poration into the tetrahedral sites helps to combat the impedance growth that stems from continuous i

232 he extracellular matrix (ECM) is required to combat the induction of programmed cell death in a varie

233 rather than specific bone marrow stroma, to combat the invasion by and survival of chemo-resistant T

234 lts advocate for new treatment strategies to combat the long-term and extremely costly effect of thes

235 nder uniparental inheritance can effectively combat the mutational meltdown, and that homologous reco

236 the societal changes that will be needed to combat the obesity epidemic in the United States and bey

237 pplicable combination therapy is proposed to combat the pathological triad of extrasynaptic NMDA rece

238 ntegrase protein interactions can be used to combat the problems associated with latent HIV virus re-

239 Novel antibiotics are urgently needed to combat the rise of infections due to drug-resistant micr

240 ds may represent a new therapeutic target to combat the spread of synucleinopathies.

241 are considered to be one of the solutions to combat the substantially increasing costs of cancer trea

242 ing is important, as this intervention could combat the transmission of obesity and diabetes to subse

243 sis disease might lead to interventions that combat the tuberculosis epidemic.

244 Organisms use molecular chaperones to combat the unfolding and aggregation of proteins.

245 a substantial need for novel therapeutics to combat the widespread impact caused by Crytosporidium in

246 atorial approaches will also be critical for combating the emergence of genetically heterogeneous sub

247 vity and may have important implications for combating the worldwide epidemic of physical inactivity

248 microscopic surface area offer a strategy to combatting the loss in signal associated with the loss o

249 al health, security and economic growth, and combatting their emergence is a public health priority.

250 ed for genetic sources of resistance to help combat them.

251 ions, these pathways may enable syntrophs to combat thermodynamic restrictions.

252 n-processing avenues is presented, which may combat these challenges through manipulation of nanoscal

253 ent and effective approaches are required to combat these epizootic events.

254 ability of vaccines and therapeutic tools to combat these infections.

255 To combat these issues, typically material properties are a

256 iles and acidophiles are being researched to combat these problems, but organisms which answer all th

257 To identify novel therapeutic approaches for combating these diseases, the viral life cycle must be u

258 study presents a "Trojan-Horse" approach to combating these tumors by using a receptor-targeted bioc

259 Nocturnal animals combat this by increasing photon catch, either optically

260 e development of new treatment strategies to combat this disease agent.

261 to guide future OPSCC prevention efforts to combat this disease.

262 e serious concerns regarding preparedness to combat this emerging virus.

263 Mtb and related species may be able to combat this harsh acidic environment which contains reac

264 g a new lead for the development of drugs to combat this neglected disease.

265 of preventive and therapeutic approaches to combat this painful viral disease in humans.

266 To combat this problem of computational complexity, a pleth

267 To combat this risk, we propose the application or extensio

268 Whilst DNA analysis has helped to combat this type of fraud some of the methods currently

269 To combat this virus, an effective vaccine would have disti

270 To combat this, techniques were developed to allow for the

271 To gain the upper hand in combating this disease, it is necessary to understand ho

272 ble detection of CP-CRE is the first step in combating this problem.

273 Combating this risk requires an understanding of chytrid

274 ing LNP confirm its therapeutic potential in combatting this lethal disease.

275 Fluoride ion channels of the Fluc family combat toxicity arising from accumulation of environment

276 lth Service started biannual distribution to combat transmission hotspots and suboptimal responses to

277 idence for mediation of the relation between combat trauma and PTSD symptoms by longitudinal changes

278 methylation across the period of exposure to combat trauma marks susceptibility for PTSD.

279 aling module downregulated in men exposed to combat traumas, one IL-12-mediated signaling module upre

280 new class of compounds with the potential to combat treatment-resistant prostate cancer.

281 Despite global efforts to combat tropical species extinctions, lack of high-qualit

282 to what degree this affects their ability to combat tumor progression remain poorly understood.

283 c antigen receptors (CARs), so that they can combat tumour cells once they are reinfused.

284 ts targeting cellular calcium homeostasis to combat type 1 diabetes.

285 vel therapeutic and prevention strategies to combat typhoid fever.

286 A virus needs to combat various cellular defense mechanisms designed to e

287 s memory B and T cells that are essential to combat various pathogens.

288 egrated vector management (IVM) strategy for combating VBD transmission.

289 nctional MRI and behavioral measures in U.S. combat veterans who served in Iraq or Afghanistan and ha

290 nctional MRI and behavioral measures in U.S. combat veterans who served in Iraq or Afghanistan and ha

291 Here, we tested 28 combat Veterans with PTSD and 28 control Veterans on a d

292 udes toward aggression in a unique sample of combat veterans with traumatic brain injury.

293 sects exploit two different RNAi pathways to combat viral and transposon infection: short interfering

294 uch NASs do not limit an animal's ability to combat viral infection, but rather their administration

295 very of vaccines and effective treatments to combat vivax malaria.

296 velopment of novel therapeutic strategies to combat WD.

297 target for the design of new antibiotics to combat widespread bacterial resistance.

298 ssing clinical need exists for 63% to 65% of combat-wounded service members and 11% to 20% of civilia

299 use of 25HC as a natural antiviral agent to combat ZIKV infection and prevent ZIKV-associated outcom

300 PTSD symptoms over a deployment period to a combat zone was significantly associated with alteration