ライフサイエンスコーパス: combined effect

1 ciated with adverse events and demonstrate a combined effect.

2 ronment, however little is known about their combined effects.

3 er obesity can be gained by evaluating their combined effects.

4 g health concern due to potential mycotoxins combined effects.

5 ensitive than plant C pools to individual or combined effects.

6 al properties in epithelial cells, but their combined effects and potential regulation of DNA repair

7 ers, (iii) additive interactions (i.e., when combined effects are equal to or not significantly diffe

8 in many human cancers, we propose that their combined effects are involved in epigenetic reprogrammin

9 However, their respective and combined effects are uncertain.

10 lored, and it is important to consider their combined effects at geographic and temporal scales that

11 We demonstrate how this combined effect can be used against cancer stem cells (C

12 gnificant relationship with urban NO2; their combined effect could be substantial.

13 These combined effects distinguish the phosphate clamp as a th

14 rthquake, and used meta-analysis to generate combined effect estimates for the most affected and less

15 We combined effect estimates from studies by using inverse

16 From these experimental studies we combined effect estimates using inverse variance meta-an

17 ession and meta-analysis were used to obtain combined-effect estimates.During the periconception peri

18 To our knowledge, such combined effect has not been documented with any other m

19 The combined effects improved LOD of the entire method by 1.

20 In hepatocytes, JNK1 and JNK2 appear to have combined effects in protecting mice from CCl4- and aceta

21 -negative NPC cell line HK1 and examined for combined effects in response to genotoxic treatments.

22 Of particular significance, their combined effect increased the risk of 'eczema and asthma

23 ses are typical features of sepsis and their combined effect is a lowering of blood pressure.

24 the development of child obesity, but their combined effect is currently unknown.We described longit

25 r phosphorus acquisition, meaning that their combined effect is greater than the sum of their individ

26 diated membrane fusion is pH dependent, this combined effect is observed at both pH 5 and pH 7.

27 The combined effect is that the rate of infection at a popul

28 For a substantial minority of users, the combined effect may be more than additive.

29 ions negatively impact biodegradation, their combined effect may enhance biodegradation rates above a

30 pic of little research, but neglecting their combined effects may seriously misguide management effor

31 Results showed that combined effect of 4-NP and daily freeze-thaw cycles can

32 ultiple regression analysis performed on the combined effect of age, body-mass index (BMI), and HbA1c

33 associated with coronary artery disease, the combined effect of all 24 fibrinogen-associated lead sin

34 The combined effect of an edible coating and a nitrogen atmo

35 ne bioaccessibility of tomato fruit, and the combined effect of blanching, ultrasonic and high intens

36 The combined effect of blood normalization and uptake time c

37 An equilibrium mesoscopic model for the combined effect of both crowding and adsorption upon the

38 ne the chosen responses, individually and in combined effect of both inputs as well (R(2) > 0.98).

39 Considering the combined effect of both pPv and ferropericlase, we sugge

40 However, the combined effect of changes in circulation and temperatur

41 =1.52; 95% CI: 1.07-2.17) suggested that the combined effect of depressive symptoms and metabolic dys

42 Most studies assessed the combined effect of different SAEs.

43 onent mixture) was used, possibly due to the combined effect of differential uptake of components by

44 trate that the dynamics are dominated by the combined effect of efficient carrier-carrier scattering,

45 less than those of the cations, indicating a combined effect of electrostatic and nonelectrostatic in

46 risoner's dilemma is greatly impacted by the combined effect of entanglement and coupling.

47 modifications in their profile, probably for combined effect of environment and microorganisms, were

48 nds mainly on rye genotype used, determining combined effect of enzymatic and acid hydrolyses, associ

49 C positions on the acyl chain) to detect the combined effect of FP-TMD interaction by titrating HA FP

50 Thus, worms exposed to combined effect of freeze-thaw cycles and 4-NP suffer hi

51 tional consequence is often generated by the combined effect of genetic and epigenetic (e.g., chromat

52 The combined effect of Grisu(R) and vitamin D3 was found mor

53 d to that in nondrylands in 2014, due to the combined effect of higher rate of increase in livestock

54 ing that the oncogenic function of Mdm2 is a combined effect of inhibiting p53 and p73 functions.

55 of future disease damage and account for the combined effect of integrated control measures to estima

56 However, information on the combined effect of iron and n-3 LCPUFA supplementation o

57 s, we identified 95 unique regions where the combined effect of low frequency variants (MAF </= 5%) p

58 s have increased persistence levels due to a combined effect of McC imported from the cultured medium

59 The combined effect of meat cooking and endogenous addition

60 thematical model reveals that expulsion is a combined effect of motility and alignment by a vortical

61 severe winters, predators, parasites, or the combined effect of multiple factors.

62 l approach to mQTL analysis by analysing the combined effect of multiple low frequency or rare varian

63 We examine the combined effect of natural selection and random drift on

64 Here, we show a combined effect of olfaction and social hierarchy on mic

65 , we have evaluated, for the first time, the combined effect of PA-X- and NS1-mediated inhibition of

66 The combined effect of pH (from 2 to 6.5) and nitrite (from

67 The combined effect of pH (from 7.2 to 3.2) and myoglobin ox

68 We assessed the combined effect of POPs on oxidative stress/glutathione

69 tion in natural populations of H. numata The combined effect of positive and negative FDS on visual s

70 thodology approach was used to determine the combined effect of pressure level, temperature and time

71 The combined effect of reduced gas exchange and changes in a

72 sions in rainfed systems are associated with combined effect of reducing mineral N fertilization, org

73 ned stable pre and post operation, while the combined effect of refractive error correction and optic

74 ctor reduction was assessed by examining the combined effect of relative reductions of 10% and 20% pe

75 missed inception can be accounted for by the combined effect of relatively high late-Holocene CO2 con

76 at the density modifications result from the combined effect of residue-specific recruitment of ions

77 The combined effect of restrained M1 and M2 macrophage activ

78 In this study we assessed the combined effect of salinity and dissolved organic carbon

79 Our results suggest that a combined effect of SNPs via WNT4-WNT5A interaction may a

80 We aimed to assess how the combined effect of soil N additions and more frequent so

81 icking membranes has been analyzed under the combined effect of SP-C and cholesterol by deuterium NMR

82 n the mimicked ATES warm well because of the combined effect of suitable temperature, sustaining biom

83 In this study, the combined effect of sulfur dioxide, caffeic acid, pH and

84 edge, this is the first study to examine the combined effect of sustained release of PRP from alginat

85 ching of its helical axis in response to the combined effect of temperature and electric field.

86 This non-nested pattern is a combined effect of temporal changes in selection pressur

87 Of all intervention combinations, only the combined effect of test and treat and annual HIV testing

88 The aim was to investigate how the combined effect of the 22q11.2 deletion and the correspo

89 in chiral liquid crystals (CLCs) due to the combined effect of the anisotropic magnetic interactions

90 The combined effect of the compound on the Mid-region i-moti

91 cases of synthetic hypermutation, where the combined effect of the drug and mutant on mutation rate

92 the sensors toward PA can be attributed to a combined effect of the ground-state charge-transfer comp

93 uctivity of the CuI films is attributed to a combined effect of the heavy element iodine and strong p

94 The combined effect of the longer peak season and greater le

95 determine how this budget is affected by the combined effect of the power station and climate change

96 behaviour of the ryanodine receptor and the combined effect of the rapid calmodulin buffer and the f

97 e detailed insights on the poorly understood combined effect of the two inhibitor types, which is abl

98 models of protein kinase signaling, that the combined effect of the two types of noise makes informat

99 ntrations in the pore waters, reflecting the combined effect of thermal desorption and advective flui

100 The combined effect of these 3 single nucleotide polymorphis

101 The combined effect of these changes is that the magnetic mo

102 The combined effect of these responses on long-term C storag

103 The combined effect of these two agents was also documented

104 terol efflux were not additive; in fact, the combined effect of these two factors together did not di

105 We estimated the combined effect of these two populations via their proje

106 ant driver of increment width by itself, the combined effect of tidal movement and temperature had a

107 ere we show that this extreme SLR event is a combined effect of two factors: an observed 30% downturn

108 ered a previously unappreciated role for the combined effect of type I IFNs, TNF-alpha, and cell surf

109 We also find that the combined effect of urban form on NO2 is larger for small

110 and hyperinduction of cyclin D1 reflect the combined effects of (a) loss of negative signals from PK

111 We investigated the independent and combined effects of a directed use of a water-based hand

112 n Zimbabwe is evaluating the independent and combined effects of a package of infant feeding and/or w

113 ated to climate change, ozone depletion, the combined effects of acidification and eutrophication, te

114 their modern counterparts, likely due to the combined effects of aging, chemical treatments, and vibr

115 effective permeabilities, which capture the combined effects of all leakage pathways within and arou

116 study aimed at investigating the single and combined effects of allergic sensitization and FLG varia

117 There has not been a broad analysis of the combined effects of altered activities of microRNAs (miR

118 A broad analysis of the combined effects of altered activities of miRNAs in panc

119 from altered circulation alone, and (2) the combined effects of altered currents plus physiological

120 environments, and ecosystems must respond to combined effects of altered species distributions and en

121 lier hypothetical modeling, we show that the combined effects of Alzheimer disease risk variants on A

122 We studied the combined effects of an additive genetic T2D risk score a

123 ical syndrome HLH generally results from the combined effects of an exogenous trigger and genetic pre

124 of this study was to examine independent and combined effects of antenatal and newborn supplementatio

125 The combined effects of anthropogenic and biological CO2 inp

126 Understanding the combined effects of anthropogenic impacts such as climat

127 These data show that the combined effects of at least three components of the Mar

128 titioning by body size and diet breadth, the combined effects of birds and ants on total caterpillar

129 hallenge for the key stakeholders due to the combined effects of chronic illness and adolescent devel

130 Combined effects of climate change and deforestation hav

131 The combined effects of climate change and habitat loss repr

132 or the first time, we present results of the combined effects of climate change and the direct effect

133 r, to identify tumorigenic drivers using the combined effects of coding and non-coding single nucleot

134 The combined effects of continuous labeling (label pumping),

135 nent analysis was also used to determine the combined effects of correlated climate variables and pol

136 Combined effects of cumulative nutrient inputs and bioge

137 tion of RacGAP1 inhibited growth through the combined effects of cytokinesis failure, CDKN1A/p21-medi

138 The combined effects of Darwinian selection and mutability c

139 ese trends were strongly associated with the combined effects of decreased precipitation and increase

140 of natural selection genome-wide due to the combined effects of demography, selfing, and genome redu

141 ent cancers in 2012 were attributable to the combined effects of diabetes and high BMI as independent

142 Developing an understanding of the combined effects of different types of uncertainty is an

143 The combined effects of DOM preoxidation on the inhibiting a

144 ariation in plumage pigmentation through the combined effects of dozens of loci.

145 This study aimed to investigate the combined effects of early-life undernutrition and urbani

146 The combined effects of eCO2 and warming on aboveground plan

147 Independent of precipitation, the combined effects of eCO2 and warming on C3 graminoids be

148 hole-plant levels, helping to understand the combined effects of endogenous and environmental regulat

149 ger than that of CNTR, presumably due to the combined effects of enhanced coupling between the embedd

150 Bladder cancer results from the combined effects of environmental and genetic factors, s

151 It is crucial to anticipate indirect and combined effects of environmental pollutants and NMs.

152 We studied the combined effects of ethanol (EtOH) and cigarette smoke e

153 Our results demonstrate the combined effects of evaporation and tide and waves on su

154 The combined effects of exposure to OA and predation by C. r

155 The combined effects of extraction conditions on total pheno

156 l whose stimulus selectivity arises from the combined effects of filtering, suppression, and response

157 nd existing strains and demonstrate that the combined effects of flp-10 and flp-17 mimic the effects

158 The combined effects of freezing and modified atmosphere pac

159 ts of each gene variant, indicating that the combined effects of functional dopamine pathway genes ca

160 Understanding the separate and combined effects of GBV-C and age on Ebola virus surviva

161 litates new study designs to investigate the combined effects of genes and the environment.

162 y may contribute to our understanding of the combined effects of genetic and environmental factors in

163 Type 2 diabetes (T2D) results from the combined effects of genetic and environmental factors on

164 t, sporadic PD is thought to result from the combined effects of genetic and environmental risk facto

165 Therefore, we aimed to quantify the combined effects of genetic and lifestyle factors on ris

166 opulation clusters representing the possible combined effects of geography and lake trophic status.

167 We study the combined effects of grain size and texture on the streng

168 Studying the combined effects of grapegrowing and winemaking provides

169 f normal lean/fat proportions depends on the combined effects of Grb10 expressed in the mother, which

170 Here, we determined combined effects of GSTM1 null and APOL1 high-risk allel

171 (The springs mimic the combined effects of half-sarcomere heterogeneity and mus

172 The combined effects of heating time, temperature, enzyme co

173 removal only (ignoring N deposition) and the combined effects of herbivore removal and current N depo

174 The purpose of this study was to investigate combined effects of high dietary iron (650 mg/kg diet) a

175 Combined effects of high-dose bisphenol A and oxidizing

176 The present work evaluated the separate and combined effects of HIV/gp120 and methamphetamine on lea

177 Moreover, the combined effects of hydrodynamics and interaction forces

178 ts, which are resolved by the individual and combined effects of hypoxic stress and stress hormones.

179 TGF-beta1 also suppressed the combined effects of IL-33 and IgE-mediated activation on

180 l is designed to measure the independent and combined effects of improved water, sanitation, and hygi

181 cean warming, we quantitatively assessed the combined effects of increased temperature and sedimentat

182 converge with pressure, suggesting that the combined effects of increased viscosity and enhanced rat

183 g precipitation with elevation is due to the combined effects of increasing LCL and decreasing TCWV.

184 e early steps of HIV-1 infection through the combined effects of inhibiting viral cDNA production and

185 This coupling is ascribed to the combined effects of ionic strength on electrostatic beha

186 hat accelerated healing processes due to the combined effects of lactate and LL37 released from the n

187 ronmental factors are comparable, suggesting combined effects of loading and soil characteristics.

188 The combined effects of logging and site preparation increas

189 hat premature activation is prevented by the combined effects of low intrinsic ubiquitin affinity, an

190 ted Cox models evaluated the independent and combined effects of LT-age and LT-MELD on graft loss (de

191 c risk of psychiatric disorders involves the combined effects of many common variants of small effect

192 We examined the independent and combined effects of maternal stress and terbutaline (use

193 The combined effects of maternal UBE3A mutation and cell typ

194 e thickness, and further illustrated how the combined effects of membrane thickness and physical prop

195 lues for this end point that is based on the combined effects of mixtures of regulated chemicals.

196 to serve as models for investigation of the combined effects of molecular recognition and spatial co

197 eopomacentrus bankieri to the individual and combined effects of multiple abiotic factors.

198 (2) plant C pool responses to individual or combined effects of multiple drivers are seldom scale-de

199 there is a paucity of data demonstrating the combined effects of multiple mediators in asthma pathoge

200 gene regulation may be additive through the combined effects of multiple regulatory regions.

201 (the creation of a lethal phenotype from the combined effects of mutations in two or more genes) has

202 ts on plant growth: net whole-soil feedback (combined effects of mutualists and antagonists), feedbac

203 and wood respiration to temperature and the combined effects of N and P were similar in magnitude.

204 demonstrated that P. aeruginosa, through the combined effects of Ndk and flagellin, upregulates the e

205 llular genes, HIV is highly activated by the combined effects of NELF-E depletion and activation of i

206 The combined effects of nicotine and lipopolysaccharides (LP

207 Here, we investigate the combined effects of nutrient (N and P) supply to the pel

208 eraction outcomes can result from the simple combined effects of nutrient availability and density-de

209 y for finite selection intensity and discuss combined effects of optionality and spatial structure.

210 l positions and, therefore, suffers from the combined effects of out-of-focus molecule activation (in

211 lation shift was a nonlinear response to the combined effects of overfishing and climate change.

212 Combined effects of oxygen level reduction in the malaxa

213 toichiometry are stronger than warming, (ii) combined effects of pairs of global change drivers (e.g.

214 tion approach is critical to deciphering the combined effects of parent contaminant (e.g., MCB) degra

215 These results highlight the combined effects of Parkin and PGC-1alpha in the mainten

216 lled SKOV-3 ovarian cancer cells through the combined effects of PDT and locally released PTX.

217 ht, which kills the cancer cells through the combined effects of PDT and site-specific PTX chemothera

218 ersist for several millennia, related to the combined effects of permafrost persistence, distant glac

219 synergistic suppression was observed by the combined effects of phages plus competing bacteria.

220 evels (7(2)), which aimed at determining the combined effects of phenanthrene and drought on the surv

221 ed light to the mice, presumably through the combined effects of photodynamic therapy (PDT) and relea

222 dynamics perspective that takes into account combined effects of physical absorption and chemical abs

223 To assess the combined effects of plant incorporation and storage time

224 This is the result of the combined effects of poor immune responsiveness and safet

225 Here we have compared the combined effects of prion seeding and mutations of prion

226 Zimbabwe that will test the independent and combined effects of protecting babies from fecal ingesti

227 erved MR behavior was modeled by considering combined effects of quantum correction to carrier conduc

228 In boreal forests, the combined effects of recent warming and increasing intens

229 use computer simulations to investigate the combined effects of recombination and spatial structure

230 tic GAG depolymerisation could be due to the combined effects of reduced molecular weight, increased

231 newly established LDR-facility Figaro on the combined effects of Se deprivation and LDR gamma exposur

232 with EA that are highly correlated with the combined effects of smoking.

233 In a third experiment, we tested the combined effects of soil and phyllosphere feedback under

234 Study of the combined effects of strong electronic correlations with

235 experience rapid functional divergence under combined effects of strongly relaxed purifying selection

236 ally, hydrophobicity is enhanced through the combined effects of surface texturing and chemistry; bei

237 Thus, this study investigated combined effects of temperature and salinity on toxicity

238 Consequently, it appears that the combined effects of temperature, pressure and oxygen con

239 e size-dependent, which is attributed to the combined effects of the acoustic streaming and acoustic

240 d by other signals than BCR, we assessed the combined effects of the AKT inhibitor MK-2206 with R406

241 tests were initially performed to assess the combined effects of the antibiotics to the cyanobacteria

242 Such performance is the result of the combined effects of the graphene on structural stability

243 We conclude that the combined effects of the increased assembly of one nAChR

244 The combined effects of the inflow and outflow maintains a c

245 mission intensity increase was attributed to combined effects of the inhibition of PET due to restric

246 sed four recombinant variants to address the combined effects of the K528R and D575N polymorphism on

247 The combined effects of the low sodium-DASH diet versus the

248 could be affected in NPC disease due to the combined effects of the lysosomal calcium defect and sph

249 The combined effects of the multiple factors, EN, EW, DE, IE

250 ith a minimum content of benzene, due to the combined effects of the Pt size and the strong metal-sup

251 Here the combined effects of the radiation reaction recoil force

252 s one of the first to compare individual vs. combined effects of the three global change drivers on t

253 bial biomass might respond to individual vs. combined effects of the three global change drivers.

254 We studied the individual and combined effects of the vitamin D receptor activator par

255 The separate and combined effects of these dietary interventions by basel

256 TI resistance mutations, we investigated the combined effects of these mutations on drug susceptibili

257 Thus, the combined effects of these stressors may represent an imp

258 Testing combined effects of these variants suggested protection

259 This profile reflects the combined effects of topographical change and ROS release

260 The combined effects of tree species and seasonality suggest

261 in which the flat slab forms because of the combined effects of trench retreat along the Peruvian pl

262 mTORC2, and activation of mTORC1 through the combined effects of TSC and RHEB as part of a multiprote

263 microcosm approach to examine the single and combined effects of two herbicides (atrazine, glyphosate

264 reased visible radiation, or to the apparent combined effects of ultraviolet and visible.

265 The combined effects of vegetation and climate change on bio

266 The combined effects of vineyard origin and winery processin

267 The combined effects of warming and O2 loss this century are

268 Investigating combined effects of warming and toxicants has been a top

269 jective was to determine the independent and combined effects of weight loss and exercise on cognitio

270 Our experiments demonstrate that the combined effects of ZnO dissolution and Zn adsorption on

271 We investigated their combined effect on AAA formation.

272 unlikely to operate independently, yet their combined effect on aboveground and belowground C storage

273 elative effect on 25OHD and tested for their combined effect on CAD in the Coronary Artery Disease Ge

274 ey interact strongly, but only through their combined effect on fitness.

275 However, their combined effect on landscape-scale net ecosystem CO2 exc

276 This combined effect on metabolite glycosylation and stress h

277 re and sample temperature, we evaluate their combined effect on organic depth profiling.

278 hether these functional polymorphisms have a combined effect on prefrontal cortical physiology and re

279 veral user-defined scores and evaluate their combined effect on ranking interaction chains linking in

280 al areas had a substantial, independent, and combined effect on the existence of interproximal papill

281 potential for comorbidity clusters to exert combined effects on asthma outcomes.

282 aled that the CLU and ApoE risk variants had combined effects on both volumetric expansion and latera

283 However, their combined effects on disease risk are not known.

284 In order to assess their combined effects on endometrial cancer, we created the t

285 ing the number of selective sweeps and their combined effects on genomic diversity in humans and othe

286 nces in plant productivity in terms of their combined effects on soil respiration.

287 n numerous experimental parameters and their combined effects on the accuracy and precision of measur

288 were investigated in order to evaluate their combined effects on the antioxidant environment.

289 s for some time, little is known about their combined effects or the scope and kinetics of such respo

290 Their combined effects orchestrate cellular adaptation to amin

291 prometastatic pathways that amplifies their combined effects, promoting synergistic cross-talk betwe

292 These combined effects protect against age-related metabolic d

293 ts have weak effects and understanding their combined effect remains a challenge.

294 The combined effects result in failed appressorium function

295 Our meta-analysis sought to determine a combined effect size of autism spectrum disorder diagnos

296 ally encourages fuel-switching, and that the combined effect slightly alters economy wide GHG emissio

297 ate change (RCP2.6), and (c) investigate the combined effects throughout the 21st century.

298 ation on how reef organisms respond to their combined effects under natural conditions.

299 This combined effect was 3.7 times (95% CI: 1.2 to 11.1) grea

300 y both warming and acidification, with their combined effects yielding the most deleterious impact.