ライフサイエンスコーパス: come at

1 sitivity for low numbers of arrays, but this came at a cost of high false positive results (24% false

2 required for rescue and that colocalization came at a cost to L. pneumophila fitness.

3 hen the invader was common, but these traits came at a cost when the invader was rare.

4 Resistance to AmB came at a great cost.

5 This remarkable improvement came at a price: adapting directions that before learnin

6 However, these benefits came at a substantial cost: The reconciliation treatment

7 zobia intensify with decreasing N supply and come at a carbon cost to the host.

8 accuracy and quality in variant calling can come at a computational cost.

9 tionality characteristic of active sites has come at a considerable cost to enzyme stability.

10 tion to the public (e.g., URL inclusion) may come at a cost in terms of message amplification; on the

11 TAC minimization may come at a cost of higher rates of dnDSAs, and TAC time i

12 f neurotransmitter biosynthesis, it may also come at a cost of insufficient development of immune sel

13 ons, which lead to new protein functions but come at a cost to protein stability.

14 ion of this restriction mechanism by HPV may come at a cost to the host by promoting cancer mutagenes

15 l to improve response precision might itself come at a cost--a cost to attenuate a proportion of intr

16 rove estimation of object properties but may come at a cost: loss of single-cue information.

17 These benefits come at a high and increasing cost, with development of

18 apeutic advances in bladder cancer care have come at a high cost to payers, providers, and patients.

19 However, these responses come at a high metabolic price, and avoiding pathogens b

20 These small advantages, however, come at a potentially significant price: the ferrocene-b

21 yme-bound cofactors is unparalleled, it does come at a price.

22 ces in cardiovascular molecular imaging have come at a rapid pace over the last several years.

23 nosis and treatment of multiple myeloma have come at a rapid pace, especially with several new drugs

24 es in the treatment of childhood cancer have come at a remarkable pace, but the search for new treatm

25 ovement in graft survival; however, this may come at a risk of rejection.

26 btained with probabilistic inference methods comes at a computational cost in terms of runtime and ma

27 smission/disequilibrium test (TDT), but this comes at a considerable cost in the need to collect DNA

28 ergy as cell size decreases, miniaturization comes at a considerable energetic cost for a phytoplankt

29 adaptation, where fitness in one environment comes at a cost in another, should lead to spatial varia

30 However, this beneficial activity comes at a cost of collateral damage when the immune sys

31 Although side-chain distortion comes at a cost of foldability, it suppresses the rate o

32 , adults' integration of sensory information comes at a cost of losing access to the individual estim

33 promoting translesion synthesis (TLS), this comes at a cost of potentially error-prone lesion bypass

34 manipulating water levels, we show that this comes at a cost of reduced attractiveness to females.

35 here help support a model in which fidelity comes at a cost of replication kinetics and may help exp

36 id starvation by decreasing GTP level, which comes at a cost to growth, while (p)ppGpp enables rapid

37 h serves other information processing roles, comes at a cost to the speed with which neurons can tran

38 ve sites for substrate recognition typically comes at a cost to the stability of the folded form of t

39 Therefore, escape from ENF comes at a cost to viral fitness and may confer enhanced

40 petitive advantage once glucose runs out, it comes at a cost while glucose is still present.

41 However, such focal processing comes at a cost, namely, functional blindness for unatte

42 dvantage and close noting that the advantage comes at a cost-one trades off prediction for generation

43 er time, but acquiring information typically comes at a cost.

44 l fate potential upon NSC activation, but it comes at a cost.

45 that successful immune response to infection comes at a cost.

46 However, this comes at a cost: those true positive sequences below thi

47 The indole production comes at a fitness cost to the highly resistant isolates

48 is only possible when antibiotic resistance comes at a fitness cost.

49 of the "normal" straight axon morphology, it comes at a great cost by interrupting axonal transport,

50 The resulting repaired chromosome comes at a great cost to the cell, as BIR promotes mutag

51 However, error tolerance comes at a high price in that these networks are extreme

52 come by increasing the sample size, but this comes at a higher cost.

53 stering cells based on phenotypic similarity comes at a loss of single-cell resolution and often the

54 This aligning of benefits comes at a potential cost, however, with the possibility

55 Such sensitivity comes at a price because it may be difficult to distingu

56 s suggest that the chemoradiotherapy success comes at a price in terms of late toxicity.

57 This capability comes at a price of a factor of three in additional qubi

58 The transparency of the proposed approach comes at a price of being less broadly applicable than M

59 minating sets optimized for small size alone comes at a price of being vulnerable to damage; dominati

60 aggressive combined therapies, but treatment comes at a price.

61 Effective immune surveillance, however, comes at a price.

62 r, this mode coupling (or splitting) usually comes at a price.

63 The improvement comes at a price: we hypothesized that random alignment

64 However, this response comes at a significant cost reflected in decreased photo

65 titution at more than one or two sites often comes at a significant energetic cost to fold stability.

66 This development of whole-body MR imaging comes at a time marked by the rapid development of moder

67 The increasing pressure to lower HAI rates comes at a time when advances in the clinical microbiolo

68 ecologically important traits in corals and comes at a time when sequencing efforts in other cnidari

69 This comes at a time when yield improvements are slowing or s

70 These benefits will come at an additional construction cost of up to $410 mi

71 is type of temperature compensation need not come at an additional metabolic cost of spike generation

72 drugs from the cytoplasm, but this response comes at an energetic cost.

73 Yet, this exquisite control over selectivity comes at an operational price that is generally not just

74 ibitors, the development of entry inhibitors comes at an opportune time.

75 s natural long term virologic control may be coming at an immunologic and clinical cost.

76 Rapid, local gain control comes at another cost: noise in the signal controlling g

77 utations that confer echinocandin resistance come at fitness and virulence costs, which may limit the

78 However, shrinking photonics has come at great cost to performance, and assembling such d

79 The forced implementation came at high cost to hospitals and with the strong endor

80 atients with MELD scores of 40 or higher but come at high pretransplantation and posttransplantation

81 their range of off-stoichiometry, eventually coming at high pressure to a diamondoid NaTl-type LiB.

82 However, the necessary calculations come at large computational costs, which has introduced

83 id changes may be a bellwether of changes to come at lower latitudes and have the potential to affect

84 Notably, this improvement to PSI-BLAST comes at minimal computational cost as SIB-BLAST utilize

85 Even though this observation comes at odds with the current view that the APC/C acts

86 order brings to biological systems, this can come at severe kinetic and thermodynamic cost.

87 and humans promote group survival but often come at some cost to the individual.

88 This adaptation could have come at some expense to the protein's housekeeping role

89 tchover to low-molecular weight heparins may come at some loss of this effect.

90 These modest improvements came at substantial cost to the Medicare program in fees

91 ields, and it has been argued that this lack comes at substantial economic costs.

92 was due to increased response initiation but came at the cost of goal-directed efficiency.

93 These benefits came at the cost of more frequent anemia and thrombocyto

94 tion conferred by these individual mutations came at the cost of reduced mating efficiency with cells

95 However, this increase in sensitivity came at the expense of a decrease in specificity.

96 tion of the sarcoplasmic reticulum (SR), but came at the expense of decreased muscle strength.

97 We find no evidence that these improvements came at the expense of employment, sales, credit ratings

98 tive in reducing hERG binding affinity, this came at the expense of higher than desired Pgp-mediated

99 2000 more than 55% of new agricultural land came at the expense of intact forests, and another 28% c

100 Translesion synthesis came at the expense of lesion-skipping replication resta

101 Bypass by DNA polymerase IV came at the expense of the inherent leading strand lesio

102 This skewing came at the expense of the number of lymphoid-primed MPP

103 nd the locality of the synaptic update rules come at the cost of a poor storage capacity, compared wi

104 nhanced thermostability does not necessarily come at the cost of activity, the process by which the m

105 eous characteristics of schematic memory may come at the cost of episode-specific information.

106 tional component of motivation, however, can come at the cost of goal-directed efficiency when a sust

107 Lower mortality rates come at the cost of more bleeding and transfusion requir

108 precisely defining known effects of interest come at the cost of much other information in the "clean

109 mprove patients' understanding, but this may come at the cost of patients' satisfaction with them.

110 bial nucleic acids; however, these responses come at the cost of potential autoimmunity owing to inap

111 the sensitivity to periodic fields, but they come at the cost of reduced bandwidth and cannot be appl

112 on of low-frequency bacteria, these advances come at the cost of sequencing read length, limiting the

113 gated simultaneously, but this precision may come at the cost of systematic inaccuracy resulting from

114 This can come at the cost of their partner's condition as mass lo

115 's robust interest in identifying causes has come at the expense of a more rigorous engagement with t

116 improved control of B-cell lymphoma, but may come at the expense of an increased risk of bacterial an

117 Dramatic changes in cardiology have come at the expense of bedside cardiology which needs to

118 icial effects on adiposity, this benefit may come at the expense of beta-cells, resulting in an incre

119 Unfortunately, these methods come at the expense of decreased acquisition speed and s

120 These advantages might come at the expense of efficiency and feasibility.

121 on to threat following violence exposure may come at the expense of encoding contextual information,

122 the benefits of photoacoustic imaging do not come at the expense of existing ultrasound functions; ph

123 ciety on intervention and cure has sometimes come at the expense of good end-of-life care.

124 Increased crypt cell numbers come at the expense of Lgr5(+) stem cells.

125 cover loss are critical for policy but have come at the expense of long-term, multidirectional analy

126 han livestock; however, those benefits could come at the expense of more intensive energy use as biol

127 nses are presumed to be costly and therefore come at the expense of other traits related to fitness.

128 s conferring new function to a protein often come at the expense of protein folding or stability, red

129 This number improvement did not come at the expense of reduced accuracy as the added dat

130 Such adaptation can come at the expense of the original protein's function,

131 er, that even if latency is achieved, it may come at the expense of tissue damage if the response is

132 The improved ranking of such decoys can come at the expense of true ligands.

133 pproaches for strengthening steels typically come at the expense of useful ductility, a dilemma known

134 d with vitamin A deprivation in Xenopus rods come at the high metabolic cost of a 15-fold increase in

135 Unfortunately, these large enhancements come at the price of high optical losses due to absorpti

136 ucture could be ignored, this robustness can come at the price of power.

137 ll factor in the DTG-containing cells, which comes at the cost of a slightly lower open circuit volta

138 Inflammation comes at the cost of a transient decline in tissue funct

139 ective by phagocytosing Abeta; however, this comes at the cost of activated innate immunity that caus

140 The balancing role of TTP comes at the cost of an increased risk of bacterial infe

141 re-ground segregation; however, this benefit comes at the cost of decreased neuronal sensitivity.

142 encing-based reference panels; however, this comes at the cost of high computational burden due to th

143 palliative surgery can benefit patients, it comes at the cost of high mortality and substantial hosp

144 However, this comes at the cost of high technical noise, including cel

145 However, this comes at the cost of impaired freezing tolerance.

146 th massive burns, but whether their survival comes at the cost of impaired quality of life is unknown

147 enes in error-containing fragments, however, comes at the cost of much lower (50%) specificity and ov

148 However, this mechanism comes at the cost of not being able to discriminate betw

149 This advantage, however, comes at the cost of other limitations.

150 However, this comes at the cost of positive-mean noise making it diffi

151 tion, changing diets, and biofuel production comes at the cost of reduced carbon stocks in natural ve

152 ed nucleotide, but this enhanced specificity comes at the cost of reduced speed of nucleotide flippin

153 This low K(M), however, comes at the cost of reduced substrate turnover.

154 The improved performance comes at the cost of requiring a more complex paper spra

155 ichness of these counting-based measurements comes at the cost of routinely handling tens to hundreds

156 bipolar disorder, long-term lithium therapy comes at the cost of severe renal side effects, includin

157 o patients, whereas this improved compliance comes at the cost of significant time, money, and staff

158 This comes at the cost of some independence and the satisfact

159 The gain of stability region around site B comes at the cost of stability in regions more distal to

160 ibozymes suggests that the acquired activity comes at the cost of substrate versatility, and indicate

161 of single amino acid substitutions typically comes at the cost of the other, regardless of whether th

162 This N reduction comes at the expense 0.7-4.6 kg CO2 eq per m(3) rainwate

163 similar regions in sequences; this, however, comes at the expense of a higher false positive rate due

164 he formation of functional globular proteins comes at the expense of an inherent aggregation propensi

165 ntage afforded by this integration, however, comes at the expense of attentional selection.

166 The declarative nature of ASP-G comes at the expense of being slower than the more dedic

167 yed by people in the richest countries often comes at the expense of CO2 emissions produced with tech

168 High hardness, however, comes at the expense of extensibility.

169 This strategy comes at the expense of genome protection because DNA br

170 with invasive pathogens, but this adaptation comes at the expense of immunopathology.

171 The advantage of being bilingual comes at the expense of increased processing demands and

172 However, the small augmented performance comes at the expense of increasing running time to O(N(2

173 it extremely high strength, but this benefit comes at the expense of other important properties like

174 impact of taxi services on cities, but this comes at the expense of passenger discomfort quantifiabl

175 Cs seen with activation of LvNotch signaling comes at the expense of presumptive endoderm cells, whil

176 g notion that the ability to respond to heat comes at the expense of protein homeostasis (proteostasi

177 tion of chaperonins as increased GFP folding comes at the expense of the ability of GroEL/S to fold i

178 nce of dark fields reduces calculability and comes at the expense of the original MOND premise, that

179 We find that spore production comes at the expense of time to complete aggregation, an

180 o use monaural cues for the horizontal plane comes at the expense of using those cues to localize in

181 cts than do these other techniques, but this comes at the price of additional assumptions.

182 y increasing I(Ca) and SR Ca(2+) content, it comes at the price of an increased risk for spontaneous

183 ever, the greater resolving power of LC x LC comes at the price of higher dilutions (thus, reduced se

184 to meet increased metabolic demand, but this comes at the price of insulin secretory dysfunction.

185 er, consequently, higher sulfonate retention comes at the price of lower sequence coverage in negativ

186 However, its simplicity comes at the price of relying on correct specification o

187 ypes of BCR-ABL+ leukemias in vivo, but this comes at the price of significant complexity.

188 may provide substantial carbon benefits, it comes at the rapidly accruing cost of woody plant specie

189 inversely correlated with an increase in oil coming at the expense of protein and vice versa.

190 ocessing of fear was not entirely automatic, coming at the expense of specificity of response.