ライフサイエンスコーパス: come into

1 "first, do no harm." These 2 principles have come into a moment of rare conflict.

2 ged when rare, I show it can invade until it comes into a producer-scrounger equilibrium with non-pun

3 ales of the roundworm Caenorhabditis elegans come into association with their hermaphroditic counterp

4 It appears that the cellular life came into being as soon as the earth's environment becam

5 ode was deciphered, but how the genetic code came into being has not been satisfactorily addressed.

6 s to explain how the sustainable growth rate came into being, how it is calculated, and how it is fla

7 tionary process before modern cell types had come into being.

8 s the mechanism by which a cognitive process comes into being, but asks whether it is at all meaningf

9 As persistence and its consequences come into clearer focus, so too does the need for clinic

10 The biologic basis of neuroblastoma has come into clearer focus.

11 r understanding of the immune system is also coming into clearer focus with the discovery of dendriti

12 abilizing and repairing the actin bundles is coming into clearer view.

13 Gabapentin has come into clinical use as adjunctive therapy in the trea

14 w assays and technologies that have recently come into clinical use or have potential for clinical us

15 enital human papillomavirus strains are just coming into clinical use.

16 ient fusion events, wherein two mitochondria came into close apposition, exchanged soluble inter-memb

17 by fluorophore on a lipid as these molecules came into close association in the lipoplex.

18 of this loop closest to loop III, appears to come into close apposition with Glu-176 of the gamma sub

19 zed intracellular calcium release membranes, come into close apposition with the plasma membrane, and

20 itial intermediate ("stalk") as soon as they come into close contact was not influenced by osmotic st

21 nd considerable time in bedrooms, where they come into close contact with allergen reservoirs.

22 preexisting liver disease, and workers that come into close contact with HEV-infected animals.

23 rospinal fluid (CSF) and send processes that come into close contact with neurons in the arcuate and

24 unlike other DNA polymerases, Rev1 does not come into close contact with the minor groove of the inc

25 osine 64, arginine 67, and lysine 279, which come into close contact with the triphosphate moiety of

26 presumptive lens and retinal epithelia first come into close contact, and have retracted by E11.5 whe

27 residues from the small and large lobes that come into close contact.

28 PKR monomers to allow the kinase domains to come into close proximity and thus enhance dimerization.

29 fer-based assay, we show that UBQLN1 and APP come into close proximity in intact cells, independently

30 T1-T1 interface of different Kv1.3 subunits come into close proximity in the ER, both in microsomal

31 ata suggest that extracellular loops 2 and 4 come into close proximity to each other in the outward-f

32 e juxtamembrane region of one molecule could come into close proximity to the active site of the othe

33 ls, suggesting that in the latter, GroEL may come into close proximity to the nitroxide label.

34 hat the side chains of the Phe(427) residues come into close proximity with one another in the lumen

35 umber of regions have recently been shown to come into close proximity with their homologous allele,

36 nally related, genetically distant loci that come into close proximity, with rRNA operons forming a s

37 ent light when two distinct cell populations come into close proximity, with the intensity of the opt

38 e Bodipy units are well-separated and cannot come into close proximity.

39 ybridization allows the membrane surfaces to come into close proximity.

40 transfer analyses suggest that the proteins come into close proximity.

41 tiple FH binding sites for C3 and heparin to come into close proximity.

42 ble domain, allowing the flanking domains to come into close spatial proximity.

43 organism's environmental interface and then comes into close contact with virtually all of the organ

44 crystal structure shows that the 107_A07 Fab comes into close proximity with the HGF/SF-binding SEMA

45 erved Arg residue present in either cofactor comes into close proximity with the nucleotide bound in

46 ent subunits of the IIA(Chb) trimer, thereby coming into close proximity with the active site residue

47 ion of microscopic events, such as two cells coming into close proximity, on a global, whole-animal s

48 ore than one fluorine-18-labeled tracer will come into common use.

49 ected for capital breeders: first, they must come into condition; at intermediate stopovers, arrival

50 confirms predictions that males and females come into conflict over optimal sex allocation when loca

51 d by society when their purely economic role comes into conflict with other human values.

52 Thus, the demand for further miniaturization comes into conflict with the superparamagnetism caused b

53 Western and Eastern Europe came into contact approximately 4,500 years ago, as the

54 imply that the reproductively isolated taxa came into contact following expansions northward around

55 ssary for previously isolated populations to come into contact and for hybridization to occur.

56 They form when the constituents come into contact at low temperature and high pressure.

57 compartmentalized on different membranes and come into contact at the time of vesicle fusion.

58 Fusion-competent blastocoelar cells and PMCs come into contact but do not fuse with one another, indi

59 -values can be used to predict which domains come into contact in an interacting protein pair.

60 tatic charging that occurs when two surfaces come into contact is familiar to everyone, and has been

61 In this model, residues come into contact only after all of the intervening chai

62 n the two ATPase domains of a dimeric enzyme come into contact upon ATP binding; for the others, chan

63 ing proinflammatory events in monocytes that come into contact with activated endothelium.

64 Healthcare workers may come into contact with fomites that contain infectious h

65 Similarly, injection drugs users may come into contact with fomites.

66 ctal mucosa may be one of the first cells to come into contact with HIV-1 during sexual transmission

67 epithelial cells are the first cell layer to come into contact with inhaled allergens, our study impl

68 days before they become senescent and again come into contact with macrophages.

69 lls, which, owing to their migratory nature, come into contact with many different microenvironments

70 s of transients visit big cities, where they come into contact with many people at crowded areas.

71 g serotonin (5-HT), a potent anorexic agent, come into contact with neuropeptide Y-ergic neurons, tha

72 Mast cells are resident sentinel cells that come into contact with pathogens early during colonizati

73 ts in peripheral blood of 189 adults who had come into contact with patients diagnosed with active TB

74 itically important because most children who come into contact with systems, including the child welf

75 Various substances likely to come into contact with technologists' hands were tested.

76 ecological relevance as they are expected to come into contact with the body, evoking touch or pain s

77 g and aggregation of subunits that failed to come into contact with the chaperone in the periplasm.

78 ough the gastrointestinal tract, which could come into contact with the colonic cells in situ, was le

79 at a surface location that was predicted to come into contact with the DNA replication machinery dur

80 e polar head groups of the lipid bilayer and come into contact with the hydrophobic interior of the m

81 ne interfaces depends on the electrodes that come into contact with the neural tissue.

82 the bilayer, allows the N-terminal helix to come into contact with the PLB binding site on the calci

83 ammonium groups (known to kill bacteria that come into contact with them).

84 erefore, BV is a serious danger to those who come into contact with these monkeys or their tissues an

85 Anesthesiologists come into contact with these patients in emergency and e

86 However, beneficial insects such as bees can come into contact with these pesticides when foraging in

87 of vaccination rates amongst humans that may come into contact with wild apes, and the availability o

88 Once species come into contact, historical niche development as a res

89 The authors find that when mating cells come into contact, they form aster-like actin structures

90 the interfacial zone where mineral and fungi come into contact.

91 duce surface precipitation when two droplets come into contact.

92 such that previously noninteracting species come into contact.

93 f determining when the tip and the substrate come into contact.

94 the presence of correct dNTPs as the IAEDANS comes into contact with a Dabcyl-labeled, one-base gappe

95 Heparin also comes into contact with a patch of positively charged re

96 ers the terminal bronchioles and alveoli and comes into contact with alveolar lining fluid (ALF), whi

97 Lyme disease spirochete Borrelia burgdorferi comes into contact with components of the alternative co

98 lls, which would be the first APCs the virus comes into contact with during infection.

99 ocessing and situations in which groundwater comes into contact with geological formations high in ur

100 rp clines in flower color where this species comes into contact with its congener, Phlox cuspidata.

101 its structure is influenced by materials it comes into contact with regularly.

102 ensive volume of the rocks and soils that it comes into contact with, including the distribution of p

103 space from its target G protein with the two coming into contact at the time of vesicle fusion.

104 heet content involves the extreme N-terminus coming into contact with distal portions of the molecule

105 g the likelihood of engineered nanomaterials coming into contact with humans and the environment.

106 the likelihood of highly susceptible humans coming into contact with infected lone star ticks, in ad

107 ated by an externally located solid particle coming into contact with the surface of a metastable aqu

108 past for this purpose, but this solution has come into criticism due to various disadvantages like no

109 products such as smoothies are increasingly coming into demand.

110 numbers of T lymphocytes and fibroblasts can come into direct contact with each other.

111 ial cells of the placenta (cytotrophoblasts) come into direct contact with immune cells in several lo

112 foreign lipids by those myeloid APCs, which come into direct contact with pathogens.

113 LECs are presumably the first cells that come into direct contact with peripheral antigens, cytok

114 llulose cross-peaks, indicating that pectins come into direct contact with the cellulose microfibrils

115 ly surrounded by fluorocarbon oil and do not come into direct contact with the hydrophobic surface of

116 idal functionalities only kill microbes that come into direct contact with the surfaces (contact-kill

117 these responses are only useful when a cell comes into direct contact with a microbe and must not be

118 or domain, the death effector domain of FADD comes into direct contact with both TRAIL and Fas/CD95 r

119 realization of artificial intelligence that comes into direct contact with humans, and to biomedical

120 to cool the liquid, when the liquid droplet comes into direct contact with liquid nitrogen.

121 al rRNA is extremely abundant and stable and comes into direct contact with translated mRNAs, it may

122 on occurs, which prevents the two drops from coming into direct contact.

123 c control, where opposing angiogenic stimuli come into dynamic balance, which can be modulated by ant

124 ew law, the Organ Transplant Act 2008, which came into effect in January 2010 and sets out principles

125 w regulations related to resident work hours came into effect July 2011, in the United States.

126 ling-like, 'morphodynamic' mode of action to come into effect when heart rate and output increase dur

127 ck cycles that are not captured in the model come into effect.

128 The inertial lift force comes into effect at relatively high flow rates, which a

129 observing how two quite different substances come into equilibrium, or by utilizing "adiabatic slopes

130 f viruses harbored by bats has only recently come into focus as a result of expanded wildlife surveil

131 (V-ATPase), a multisubunit proton pump, has come into focus as an attractive target in cancer invasi

132 s crystalline materials, which have recently come into focus as analyte-specific active elements in t

133 x (LUBAC)-mediated linear ubiquitination has come into focus due to its emerging role in activation o

134 ntly devastating clinical syndrome which has come into focus for its association with neuromyelitis o

135 -dimensional (3D) optical metamaterials have come into focus recently, including the realization of n

136 and its clinical implications have recently come into focus with observational studies demonstrating

137 till lacking, some key molecular events have come into focus.

138 e cellular basis of disease are beginning to come into focus.

139 sights into circadian function have recently come into focus.

140 cise mechanistic roles are only beginning to come into focus.

141 einvasive respiratory lesions, have recently come into focus.

142 induction of gene expression--have recently come into focus.

143 ein synthesis requirements-has only recently come into focus.

144 elationship between ER shape and function to come into focus.

145 portance of these modifications has begun to come into focus.

146 ion in response to growth factor binding are coming into focus and involve cbl-mediated receptor ubiq

147 A consensus picture is coming into focus around two proteins (called PER and TI

148 chanisms underlying its actions are only now coming into focus, following the recent discovery that a

149 immune tolerance to FVIII, are increasingly coming into focus.

150 l alterations in the nucleolus are presently coming into focus.

151 e shapes of several individual organisms are coming into focus.

152 s activity by covalent modification are just coming into focus.

153 s that proteases play in these organisms are coming into focus.

154 elsen forms of congenital LQTS are gradually coming into focus.

155 many new and presently unresolved issues are coming into focus.

156 is just one part of a picture that is slowly coming into focus.

157 new rules governing antigen presentation are coming into focus.

158 ly and survival during embryogenesis is just coming into focus.

159 etter fit than the date when the legislation came into force (26 March 2006), suggesting an anticipat

160 the form of the Human Tissue Act 2004, which came into force from September, 2006.

161 Persons with intellectual disability come into frequent and underreported contact with the le

162 European Convention on Rights and Freedoms, came into full operation on Oct 2, 2000.

163 for helper epitopes from tumor antigens has come into full swing.

164 at now require less support at the time they come into function, the root growth spurt no longer conf

165 ayer portion of bound membranes so that they come into intimate contact, the damping of dimpling woul

166 nence rates with some biological slings have come into light.

167 ase reorganization such that "optimal" phase comes into line with temporally expected critical events

168 ation approaches zero (i.e., as the surfaces come into molecular contact).

169 an, and it has been intercepted in shipments coming into North America and Australia.

170 These issues come into particular focus in the hippocampus.

171 dentifying which host proteins and complexes come into physical contact with the viral proteins is cr

172 tion due to signals transduced when one cell comes into physical contact with another cell.

173 ncertainty band where other factors probably come into play - a response type that influences stand d

174 the conditions for negative reinforcement to come into play at a time when tolerance, in the form of

175 extent to which multiple cellular mechanisms come into play can differ across species.

176 tissues, but that alternative exit receptors come into play during chronic inflammation.

177 However, the structural principles that come into play during the transition from a loose chain

178 it clear that numerous regulatory activities come into play during the transition from one homeostati

179 triction, the infinitesimal model appears to come into play even when only a few loci are involved, m

180 al factors, such as residential segregation, come into play in determining Hispanic health for the US

181 These mechanisms come into play in response to a high influx of Cu or dur

182 novel evolutionary and ecological processes come into play in the nonequilibrium conditions at expan

183 ood although a number of factors may clearly come into play including differences in uptake, metaboli

184 ossible that muscarinic receptors in the PMN come into play only under specific conditions such as ac

185 importantly we demonstrate that V1 and V5/MT come into play simultaneously and seem to be functionall

186 to folate deprivation, and other factors may come into play to account for the marked increases in co

187 If infection progresses, type I IFNs come into play to enhance viral resistance and induce pr

188 tively, peripheral inhibitory mechanisms may come into play when appetitive and aversive stimuli are

189 Similar effects may come into play when attention is sustained on an object

190 However, we find that other factors come into play, namely, atomic radii, bonding orbital ov

191 ic trait for which complex gene interactions come into play.

192 ted acting on doping, since other parameters come into play.

193 der what conditions these different controls come into play.

194 nmental, economic, and societal factors will come into play.

195 to elucidate how long-range gene regulation comes into play and how histone modifications and distal

196 Nevertheless, how this kind of GB motion comes into play at the atomic level has not been fully r

197 ons, whereas the clathrin-based SE mechanism comes into play only at higher levels of stimulation and

198 lcium accumulation during I/R, while the MPT comes into play only upon reperfusion.

199 This role comes into play primarily during brief high-frequency st

200 One such mechanism comes into play when the quantitative increase in some e

201 At this point, the second mechanism comes into play whereby the peroxo intermediate decays a

202 V (P2(1) at 0 GPa; P2(1)/c at high pressure) comes into play, slightly more stable than phase III in

203 ts the curvature force field of the membrane comes into play.

204 addition of the C-OMe bond to Ni(0) species comes into play.

205 e UPP function is compromised, and autophagy comes into play.

206 e SWNT growth process, as one of the effects coming into play in PECVD.

207 The transmembrane 4 superfamily (TM4SF) has come into prominence for its association with a wide ran

208 As new foods and food components come into prominence, and as analytical methods evolve,

209 with the glucose syrup, the delta(13)C ratio comes into prominence.

210 that polyQ domains from different molecules come into proximity in the fibrils.

211 omprised of diversely located residues which come into proximity only upon proper assembly.

212 h occurs over at least 3 days as the neurons come into proximity to the hematoma, the "black hole" mo

213 hat the T-loop of GlnB is flexible enough to come into proximity with both the C- and N-terminal regi

214 om that allows its terminus to fold back and come into proximity with the phenolic ring.

215 egins when two cells of opposite mating type come into proximity.

216 asing the energy of binding; and (vi) Arg302 comes into proximity with protonated Glu325, causing dep

217 This interpretation came into question when pneumolysin was observed to be r

218 ested to be equivalent by early studies, has come into question as groups with varying levels of expe

219 However, Levy processes too have come into question based on the observation that in patc

220 Though these claims have recently come into question, the proposal that many animals forag

221 ility in a number of cell types has recently come into question.

222 21ras-mediated signaling in these events has come into question.

223 ents, the 10-year revaccination schedule has come into question.

224 lity of their account of attractiveness bias comes into question, and it is unclear whether it offers

225 ng programs to prevent child maltreatment is coming into question, rigorous review of program compone

226 ification of cytoplasmatic reaction networks comes into reach of the current generation of scientists

227 olecular stop signal, when the binding sites come into register, the assembly terminates giving an ol

228 is and regeneration are only now starting to come into relief.

229 m" exhibits sharp peaks when the Fermi level comes into resonance with electronic quasi-bound states

230 hondrial DNA (mtDNA) lineages, many of which came into secondary contact during the Holocene.

231 species with incomplete prezygotic isolation come into secondary contact, the outcome of their intera

232 cently diverged species that hybridize after coming into secondary contact, may differ only in restri

233 ndant regulatory RNA molecules have recently come into sharp focus.

234 lecular activities in healthy individuals is coming into sharper focus, creating a unique set of chal

235 oliferation, differentiation and survival is coming into sharper focus.

236 Alzheimer or Parkinson's diseases, and hence came into the focus of research interest and as a therap

237 The synuclein gene family recently came into the spotlight, when one of its members, alpha-

238 roperties isolated using this scheme has now come into the limelight as a new gene therapy for diverg

239 es is a striking finding, which has recently come into the limelight because it can be linked to prim

240 As clinical trials have come into the mainstream of clinical research in medicin

241 A range of cardiovascular biomarkers have come into the routine clinical use for the diagnosis and

242 w metabolic tricks and new metabolic players come into the scene.

243 Once obscure, the cilium has come into the spotlight during the past decade.

244 pe-2 effector cells, basophils have recently come into the spotlight for their role in the initiation

245 Peroxynitrite has come into the spotlight in recent years.

246 icrobiota as a regulator of autoimmunity has come into the spotlight.

247 rting events when a stadium's display screen comes into the camera's view.

248 round state, the so-called multi-stable LCD, comes into the limelight due to the great potential for

249 collaborations and training for researchers coming into the field of craniofacial studies.

250 t permit policy to prevent O. niloticus from coming into the islands.

251 n the course of insertion, membrane proteins come into thermodynamic equilibrium with the lipid membr

252 n microtubule sliding only when microtubules come into transient contact with the network.

253 ear of clinical contact for all new patients coming into treatment for psychosis in the region of Dum

254 c outgrowth of cancer cells are beginning to come into view.

255 chanisms that underlie this process begun to come into view.

256 leukocyte recruitment to the CNS are slowly coming into view.

257 he genetic alterations that cause cancer are coming into view.

258 leles, but new PCR-based genetic markers are coming into vogue, with vastly increased numbers of alle

259 nt's level of airway inflammation is already coming into wider clinical use.

260 In this group, combination therapy came into widespread use in only 1996.

261 ng rich sources of growth factors, have also come into widespread periodontal regenerative use.

262 However, KIEs have not come into widespread use in enzymology, due in large par

263 All-ceramic crowns are coming into widespread use because of their superior est