ライフサイエンスコーパス: commit

1 gue that such bottom-up proposal is bound to commit a mistake of reification: It treats the abstract

2 a Man7GlcNAc2 structure does not inevitably commit a protein for ER-associated protein degradation.

3 the derivation sample, 830 (1%) individuals committed a violent offence within 12 months of their pa

4 to the deposition of their fingermarks while committing a crime.

5 ior within 6 months pre-baseline, and 8 (4%) committed acts of violence during the follow-up time per

6 hile to allow and even encourage students to commit and correct errors while they are in low-stakes l

7 s medication treatments for CUD, 20 years of committed and high-quality research in the human laborat

8 ll require not just financial resources, but committed and sustained efforts to address a range of ot

9 We calculated the percentage of committed and uncommitted caregivers.

10 stages of development, we show that sexually committed, AP2-G(+) mature schizonts specifically upregu

11 rium Anabaena sp. strain PCC 7120 terminally commits approximately 10% of its cells to become special

12 al cells undergoing angiogenesis, but not in committed arterial endothelial cells.

13 nity-based interventions were more likely to commit as donors (7 cluster-RCTs; 6015 participants; rel

14 ommit to a suboptimal strategy or who do not commit at all.

15 MbtA catalyzes the first committed biosynthetic step of the mycobactins, which ar

16 Committed bone marrow macrophage precursors and blood mo

17 Murine lung mast cells arise from committed bone marrow-derived progenitors that enter the

18 People commit both time and attentional resources to an engagin

19 Homicides committed by intimate partners, as identified in the Fed

20 uring a computer game to a variety of errors committed by others during movie clips (e.g., figure ska

21 The identification of the committed cardiomyoblast that retains proliferative pote

22 ates the transition between pluripotency and committed cell lineages, in both let-7-dependent and let

23 lect reprogramming by TCF3-HLF of a lymphoid-committed cell of origin toward a hybrid, drug-resistant

24 Bcl-2 associated X, apoptosis regulator) can commit cells to apoptosis via outer mitochondrial membra

25 embrane (MOM) induce structural changes that commit cells to apoptosis.

26 abilize the outer mitochondrial membrane and commit cells to apoptosis.

27 of DNA methylation characteristic of lineage-committed cells are established at the exit from pluripo

28 nal profiling at E9.5 reveals that endocrine-committed cells are molecularly distinct, whereas multip

29 ors feed production of Neurog3(HI) endocrine-committed cells during pancreas organogenesis.

30 Differentiation of lineage-committed cells from multipotent progenitors requires th

31 To this end, we treated lineage-committed cells with AZA and screened a number of differ

32 e promoters in human pluripotent and lineage-committed cells, identifying putative target genes for k

33 phosphatidylserine at the surface of fusion-committed cells.

34 igration, and the differentiation of lineage-committed cells.

35 omes from pluripotent stem cells and lineage-committed cells.

36 rough regulation of tbx16 and msgn1, thereby committing cells to a PM fate.

37 letal progenitors, maturing osteoblasts, and committed chondrocytes.

38 indings reveal how signaling can fine-tune a committed chromatin state by phosphorylation of a pivota

39 targeting module induces rapid, private, and committed client transfer to TRC40 for successful biosyn

40 in mesenchymal progenitors reduced B-lineage committed CLPs, while conditional Cxcl12 or Scf deletion

41 same reparative capacity as physiologically committed CNS-derived precursors.

42 stituted a significant minority of those who committed college rape and did not compose the group at

43 We aimed to identify a committed community and mechanisms needed to develop EHS

44 cally indistinguishable from their asexually committed counterparts, defining their characteristic ge

45 ere we show that pre-existing, intrinsically committed DASC(p63/Krt5) undergo a proliferative expansi

46 cell fates, including renewed stem cells and committed differentiating progenitors, are specified dur

47 luripotent stem cells via progressively more committed downstream progenitors.

48 at today's greenhouse gas levels may already commit Earth to an eventual total warming of 5 degrees C

49 The committed effective doses due to (210)Po from ingestion

50 Accounting for these committed emissions, we estimate that stopping deforesta

51 ndoscopy serology is often unavailable, thus committing endoscopists to take routine duodenal biopsie

52 isate dioxygenase (HGO), which catalyzes the committed enzymatic step in homogentisate catabolism.

53 enylalanine ammonia-lyase (PAL) is the first committed enzyme in the pathway; it diverts the central

54 lmitic acid by Delta0-ELO1, thus acting as a committing enzyme for galactolipid production.

55 is thaliana mutants for the three allosteric committed enzymes in the biosynthetic network: threonine

56 Humans often commit errors when they are distracted by irrelevant inf

57 as well as right hemispheric stroke patients commit errors when transcoding numerals including zeros.

58 During both self- and other-committed errors activation was seen in the striatum, te

59 agnetic resonance imaging activation to self-committed errors during a computer game to a variety of

60 dult hematopoietic stem/progenitor cells and committed erythroid progenitors.

61 response have higher decision thresholds and commit fewer erroneous responses.

62 Committed gametocytes are refractory to the commonly use

63 B cell formation; however, the signals that commit GC B cells to the memory pool remain unclear.

64 of glycolysis because it catalyzes the step committing glucose to breakdown.

65 s folding in the ER lumen and preferentially commits glycoproteins trapped in partially structured st

66 tor marker Nestin but not Math1, a marker of committed granule neuron progenitors.

67 er, the function of low GATA-3 expression in committed group 3 ILCs (ILC3 cells) has not been identif

68 sessions; casual (group 2), 2 to 3 sessions; committed (group 3), 4 to 5 sessions; and Masters athlet

69 Committed Hdc(+) myeloid cells lie in close anatomical p

70 deferoxamine mesylate (DFO), with the first committed heme precursor alpha-aminolevulinic acid (ALA)

71 with extremely violent behavior (at least 10 committed homicides, attempted homicides or batteries).

72 e outer mitochondrial membrane and therefore commit human cells to apoptosis.

73 nd cytotoxic T cells that differentiate from committed ILC precursors (ILCPs).

74 on of programmed death 1 (PD-1(hi)) marked a committed ILC progenitor that was essentially identical

75 iated with nearly half of all violent crimes committed in the United States; yet, a potential neural

76 able to prosecute transplant-related crimes committed in their territory, but transplant recipients,

77 or for lycopaoctaene biosynthesis, the first committed intermediate in the production of lycopadiene.

78 new layer of communication between crossover-committed intermediates and the synaptonemal complex tha

79 ations of endogenous gene expression in fate-committed iPSC-derived neurons.

80 pore complex by this interaction irrevocably commits it to the formation of the membrane-inserted gia

81 mental, and environmental information before committing key resources to reproduction.

82 of 4.8 (3.8-5.7) Mg C ha(-1) , compared to a committed loss of 11.9 (7.2-16.6) Mg C ha(-1) within are

83 ls function as highly proliferative, lineage-committed MaSCs that are heterogeneous in their expressi

84 is review will focus on our understanding of committed megakaryocytes and platelet release in vivo an

85 begins with invasion by a single, asexually committed merozoite and ends, 48 hours later, with a sch

86 ication strategies for primary human lineage-committed Mk and E progenitors identified as CFU-Mk and

87 s in hematopoietic progenitor cells prior to committed monocyte/macrophage or dendritic cell differen

88 sels regulate monocyte conversion, a form of committed myeloid cell fate regulation.

89 ic acid-induced maturation of EML cells into committed myeloid cells, a process that can be documente

90 ogenitor cells (HSPCs) compared with lineage-committed myeloid-restricted progenitor (MyePro) cells.

91 However, Myf5 is not restricted to committed myoblasts in embryos but is also expressed in

92 Here, we evaluate Troy/TNFRSF19 as a segment-committed nephron progenitor cell marker.

93 between nation states, and the email and co-commit networks between developers of open source softwa

94 Loss of Pbx1 expression in neuronally committed neuroblasts in the rostral migratory stream in

95 pool maintenance or derivation of endocrine-committed Neurog3(HI) cells, respectively.

96 Post-mitotic committed neurons become susceptible to ZIKV infection a

97 ving recruitment of pre-positioned, variably committed neurons into memory networks.

98 Committed nodes are assigned a commitment strength, w, d

99 Such model has committed nodes that can stick to a single opinion for s

100 ed osteoclast differentiation, the number of committed osteoprogenitors, alkaline phosphatase activit

101 atic ducts and pancreatic duct glands harbor committed pancreatic progenitors.

102 5, the compound effectively treated sexually-committed parasites, and was both safe and efficacious i

103 and also metabolic features of cells in the committed phase of the cell division cycle.

104 panded IgM(+) memory and plasma cell lineage committed populations, and favored secretion of IgM, unl

105 onses during the anticipation of guilt about committing potential everyday moral transgressions, and

106 Pre-B ALL originates from a committed pre-B cell or an earlier progenitor, with pote

107 (cDCs; cDC1s and cDC2s) develop from lineage-committed pre-cDCs.

108 The discovery of multiple committed pre-DC populations opens promising new avenues

109 T-lineage committed precursor thymocytes are screened by a fate-de

110 underlying the transition from progenitor to committed precursor, integrating known and novel molecul

111 In committed pro-B cells, Brg1 regulated contraction of the

112 The transition from a committed progenitor cell to one that is actively differ

113 Similar segment-committed progenitor cells are thought to be involved in

114 Erythropoiesis, in which committed progenitor cells generate millions of erythroc

115 During kidney development, progressively committed progenitor cells give rise to the distinct seg

116 However, markers for most segment-committed progenitor cells remain to be identified.

117 pocytes, multipotent mesenchymal stem cells, committed progenitor cells, fibroblasts, endothelial cel

118 ation of hematopoietic stem cells (HSCs) and committed progenitor cells.

119 lts in more aggressive AML than transforming committed progenitor cells.

120 lls (HPCs), which include eosinophil lineage-committed progenitor cells.

121 stasis, whether blood cells are derived from committed progenitor or mutipotent stem cell activity re

122 r and growth potential of eosinophil-lineage-committed progenitors (EoP) were assayed in 21 severe eo

123 Eos-lineage-committed progenitors (EoPs) were noted to express high

124 ture hematopoietic cells, clonogenic lineage-committed progenitors and HSCs.

125 have higher mitochondrial mass than lineage-committed progenitors and mature cells.

126 in vivo We suggest that ATOH7 specifies RGC-committed progenitors and that Dlx1 and Dlx2 function bo

127 The labeled HSCs rapidly contributed to committed progenitors of all lineages and to mature myel

128 ST-HSCs, MPPs, and total numbers of committed progenitors were increased in the spleen of Kl

129 stem cells, accompanied by an enrichment of committed progenitors, formation of hypertrophic sebaceo

130 ppresses Cebpa in stem cells but not in more committed progenitors.

131 g cell cycle, which is restricted to myeloid committed progenitors.

132 ate HSC quiescence and the supply of lineage-committed progenitors.

133 could control the differentiation of lineage-committed progenitors.

134 monocytes via similar but distinct monocyte-committed progenitors.

135 , ensuring appropriate production of lineage-committed progeny and suppressing tumor formation.

136 onocyte progenitors (GMPs) and their lineage-committed progeny: granulocyte progenitors (GPs) and mon

137 itochondrial enzyme that catalyses the first committed reaction and rate-limiting step in the urea cy

138 hate suggest that GrTPS2 catalyzes the first committed reaction in the biosynthesis of grindelic acid

139 This LULCC implies a committed release of 0.9 Pg C (95% CI: 0.4-1.5) across t

140 -season resilience" to predict the long-term committed response of the forest, should the state of th

141 In both the transient and predicted committed responses, there is an increasing uncertainty

142 groups consisting of two people who are in a committed romantic relationship.

143 As sexually committed schizonts comprise only a sub-population and a

144 However, the role of PRC2 in lineage-committed somatic cells is mostly unknown.

145 al mesoderm progenitors represent a distinct committed state that is unable to differentiate to neura

146 n their probability to transition to another committed state.

147 s (stem and differentiated) via an unstable (committed) state.

148 m quantitatively assesses the progenitor and committed states in single-cell RNA-seq data sets in a n

149 amination of Phe to trans-cinnamic acid, the committed step for the major pathway of Phe metabolism.

150 ylserine synthase (PSS), which catalyzes the committed step for the synthesis of major phospholipids

151 idate phosphatase (PAP), which catalyzes the committed step for the synthesis of triacylglycerol in S

152 BACE-1 cleavage of APP is the committed step in Abeta synthesis.

153 e-1-carboxylic acid synthase gene, the first committed step in ethylene biosynthesis compared with wi

154 f the Mcm2-7 replicative DNA helicase is the committed step in eukaryotic DNA replication initiation.

155 ne synthase (diTPS) that catalyzes the first committed step in PAB biosynthesis.

156 Cyclooxygenases (COXs) catalyze the committed step in prostaglandin (PG) biosynthesis.

157 oteins interact with ribosomal protein S6, a committed step in ribosome biogenesis.

158 sitive mannosidase for catalyzing this first committed step in Saccharomyces cerevisiae We reconstitu

159 A role of SdCPS2 in catalyzing the committed step in salvinorin A biosynthesis is supported

160 ral membrane enzyme catalyzing the final and committed step in the acyl-coenzyme A (CoA)-dependent bi

161 drosterone, a process representing the first committed step in the biosynthesis of androgens.

162 ruginosa, we focused on inhibiting the first committed step in the biosynthesis of lipid A, the deace

163 syl diphosphate, is the product of the first committed step in the enzymatic synthesis of a range of

164 absence is the characterization of the first committed step in the pathway, namely the 3-hydroxylatio

165 stereospecific cyclization of chalcones is a committed step in the production of flavonoids.

166 cetyl-CoA carboxylase (ACCase) catalyzes the committed step of de novo fatty acid biosynthesis.

167 feryl alcohol radicals to pinoresinol as the committed step of lignan biosynthesis.

168 oxyphenylpyruvate dioxygenase catalyzing the committed step of plastoquinone and tocopherol biosynthe

169 drogenase (PHGDH), which catalyzes the first committed step of serine biosynthesis, is overexpressed

170 he 'gatekeeper' of glycolysis, catalyses the committed step of the glycolytic pathway by converting f

171 yltransferase activities represent the first committed steps in the biosynthesis of a large number of

172 hat Ascl3 marks progenitors that are lineage-committed strictly to microvillar cells and Bowman's gla

173 pre-DC compartment contains distinct lineage-committed subpopulations, including one early uncommitte

174 C subset and two CD45RA(+)CD123(low) lineage-committed subsets exhibiting functional differences.

175 5-Aminolevulinic acid (ALA) is the first committed substrate of tetrapyrrole biosynthesis and is

176 poly-ubiquitin chains are removed only from committed substrates and fast enough to prevent their co

177 icient degradation but must be restricted to committed substrates that are engaged with the ATPase mo

178 mortem brains from depressed persons who had committed suicide and controls.

179 1455 military personnel committed suicide from 2005 to 2011.

180 est that among army personnel or marines who committed suicide, those with infantry or special operat

181 ng the conduct of the study, one participant committed suicide.

182 One patient committed suicide.

183 These enzymes either commit sulfur metabolism to cysteine synthesis from homo

184 omoted the formation of interleukin-4 (IL-4)-committed T follicular helper (Tfh) cells.

185 ons to diets of tougher, harder foods and to committed terrestrial bipedality.

186 B cells were required to expand IL-4-committed Tfh cells during the sensitization phase, but

187 ironment in activating effector functions of committed Th17 cells, which may have important implicati

188 in stem cells but, when activated, helps to commit these cells to developmental lineages through a s

189 Activation of the TCR beta (Tcrb) locus in committed thymocytes is a critical process for continued

190 has an important regulatory role in lineage-committed tissue cells by suppressing overactivation of

191 n and this enables mesodermal progenitors to commit to a blood fate.

192 Decisiveness is the ability to commit to a decision quickly and efficiently; in contras

193 , RUNX1(+) FGRS-transduced endothelial cells commit to a haematopoietic fate, yielding rEC-HSCs that

194 l and mesodermal cells to enable mesoderm to commit to a hematopoietic fate.

195 eracting with platelets, Ly6C(low) monocytes commit to a meticulous patrolling of the endothelial wal

196 Cells that mutate or commit to a specialized function (differentiate) often u

197 r time from feedback but are also allowed to commit to a strategy at any time, eliminating all other

198 orrect epiphany) but not always of those who commit to a suboptimal strategy or who do not commit at

199 The challenge is to commit to achieving adequate lengths of stay in low- and

200 These condensations commit to an osteogenic identity and suppress chondrogen

201 adjudicate the decision of whether or not to commit to cell death, but also release toxic proteins cu

202 Individuals requesting others to commit to cooperate (proposers) incur a cost, while thei

203 pair/remodelling of many tissues, where MSCs commit to different lineages dependent on the cues in th

204 emonstrate that cells with ALDH activity can commit to either endocrine or acinar lineages, and can b

205 PK pathway shows that individual progenitors commit to either fate asynchronously during blastocyst d

206 ryogenesis, cells must exit pluripotency and commit to multiple lineages in all germ-layers.

207 uration of time that viewers were willing to commit to narrative videos.

208 Cell lineages of the early human gonad commit to one of the two mutually antagonistic organogen

209 c research into open scientific research and commit to Open Science principles.

210 ) increased the participants' willingness to commit to organ donation themselves, donate the organs o

211 he sham group (mainly because they could not commit to receiving treatment every week).

212 s, a terminal UPR program ensures that cells commit to self-destruction.

213 The decision to commit to spermatogenic differentiation coincides with t

214 ats1/2 forces hepatoblasts or hepatocytes to commit to the biliary epithelial cell (BEC) lineage.

215 ol when and how multipotent progenitor cells commit to the desired cell fate.

216 nts, and pupillary responses of subjects who commit to the optimal strategy (correct epiphany) but no

217 thelial cells in the adult pancreas that can commit to the pancreatic lineage following proliferation

218 In the thymus, hematopoietic progenitors commit to the T cell lineage and undergo sequential diff

219 rs relinquish competence for other fates and commit to the T cell lineage by turning on Bcl11b, which

220 ment of germ cells during fetal life as they commit to, and prepare for, oogenesis or spermatogenesis

221 ion, particularly at a checkpoint before RFC commits to ATP hydrolysis.

222 e (UPR) is an ancient signaling pathway that commits to life-or-death outcomes in response to proteot

223 rreversible epigenetic changes, cells become committed to a B-blast fate <12 days post-infection and

224 ached a stereotyped level before the monkeys committed to a decision.

225 cantly enriched by the introduction of nodes committed to a single opinion.

226 CR scanning for antigen before the T cell is committed to activation.

227 ASCO is committed to addressing the needs of sexual and gender m

228 tion increased as common myeloid progenitors committed to become granulocyte-macrophage progenitors a

229 In BMMs committed to become osteoclasts by RANKL treatment, Saa3

230 T1 B cells expressing surface ADAM10 were committed to becoming MZB cells in vivo, whereas T1 B ce

231 ollaboration comprises three global partners committed to capturing, preserving and providing compreh

232 tion because substrates must be irreversibly committed to degradation before Rpn11 acts.

233 g degree of flexibility, with cells normally committed to differentiation able to recover stem cell c

234 ll self-renewal capacity, while the other is committed to differentiation.

235 studies demonstrate that neural progenitors committed to dopaminergic fate survive and integrate bet

236 occur as common lymphoid progenitors become committed to each of the ILC lineages further underscore

237 izont releasing newly formed merozoites, all committed to either continued asexual replication or dif

238 In 2006, China committed to eliminating measles by 2012; to this end, t

239 ing the World Health Organization (WHO), has committed to ending the AIDS epidemic and to ensuring th

240 Urgent action is needed if we are committed to ending the TB epidemic.

241 National Human Genome Research Institute is committed to establishing foundational approaches to stu

242 to processing, so that all cleaved RNAs are committed to faithful modification.

243 ltivar 30-35 Mya after the first attine ants committed to farming.

244 les/pro-basal bodies are multipotent and not committed to form either a 9+2 or 9+0 axoneme.

245 We excluded patients not committed to full respiratory support.

246 tiate into a megaspore mother cell, which is committed to giving rise to the female germline.

247 Cells committed to growth arrest and shmoo formation exhibited

248 abilized as the consensus site nucleotide is committed to hydrolysis.

249 ereas Ly6C(lo)TLR2(hi) monocytes were mainly committed to IL-10 and TNF-alpha production during T. cr

250 T17 cells are a subset of gammadelta T cells committed to IL-17 production and are characterized by t

251 The ACP remains committed to improving care for patients throughout and

252 lymphoid progenitors, which are subsequently committed to innate lymphoid lineages in the alpha-lymph

253 , we found that human podocytes in vitro are committed to internalizing albumin through a receptor-me

254 The Canadian government recently committed to introduce legislation to restrict the comme

255 unity evolving around this workbench, we are committed to keep the workbench up-to-date for future st

256 ng medical professional oncology society, is committed to lessening the burden of cancer and as such

257 rogenitor stem cells, which may have already committed to lineage despite maintaining hallmarks of pl

258 hieving these goals is the financing that is committed to maintaining biodiversity; however, financin

259 the response to DSBs once cells have already committed to mitosis.

260 We demonstrated that human podocytes are committed to performing endocytosis via a receptor-media

261 interleukin-6 (IL-6) only regulates B cells committed to plasma cells in response to T-dependent (TD

262 of country and global progress; Countdown is committed to playing its part in this effort.

263 de 0 to 1 in the infarct-related artery, and committed to primary percutaneous coronary intervention,

264 troke Association is uniquely positioned and committed to promoting the adoption of comprehensive wor

265 s driven MPA establishment, with 193 parties committed to protecting >10% of marine environments glob

266 roblem, about 200 governments worldwide have committed to protecting 10%-20% of national coastal mari

267 Clinical Virology recognize that the FDA is committed to protecting patients.

268 for the global eradication of polio and has committed to provide an additional $35 million each year

269 i results in up to 40% of all CD8(+) T cells committed to recognition of the dominant TSKB20 and subd

270 While the UK has committed to reduce CO2 emissions to 80% of 1990 levels

271 Countries in the Indian subcontinent have committed to reducing the incidence of kala-azar, a clin

272 ricytes (MPs), which are resident stem cells committed to reparative angiomyogenesis.

273 e-saving compound by special interest groups committed to repealing environmental regulations.

274 nothing mode, such as bristle worms: females committed to reproduction spend roughly half their body

275 reported, and all participating centers have committed to support their consecutive experience with t

276 WHO is committed to supporting country, global, regional, and n

277 alling promotes TG activity in keratinocytes committed to terminal differentiation by direct inductio

278 Conversely, bone-resident cells committed to the adipocytic lineage inhibit hematopoiesi

279 Sixth, Kraepelin was committed to the application of the medical disease mode

280 rize the cardiomyoblast intermediate that is committed to the cardiomyocyte fate, and we characterize

281 ese include the existence of networks deeply committed to the cause, the potential to link with globa

282 ABCs), that were distinct from ASCs and were committed to the MBC lineage.

283 Most governments have committed to the set of Sustainable Development Goals es

284 otes and archaea, cis-PT is the first enzyme committed to the synthesis of dolichyl phosphate, an obl

285 tion schema demands that those who are truly committed to their work will make it the central or sole

286 red in the number of draws required prior to committing to a decision, but not in decision accuracy.

287 favour of the different alternatives before committing to a decision.

288 e images were repeated, and more cautious in committing to a definitive answer.

289 (in older juveniles) abundant spermatogonia committing to gametogenesis (high KIT(+)).

290 dly satisfy task demands without necessarily committing to learning, as the relative permanence of le

291 ry esophageal pH/impedance monitoring before committing to lifelong PPIs to help distinguish GERD fro

292 these functional centers is a checkpoint for committing to spacer removal.

293 nd direct testing on NHP-induced GVHD before committing to the intensive NHP studies that are being i

294 ast with those in the AD group, who commonly committed traffic violations, often related to cognitive

295 The RMNCH fund committed US$175.7 million to 19 countries to support st

296 strategy, although all parties seem to have committed violations.

297 and bipolar disorder) have elevated risks of committing violent acts, particularly if they are comorb

298 ing lags significantly below equilibrium or "committed" warming.

299 ft failure, and improve longer-term outcomes.COMMIT was formed in 2015 and is composed of 20 leading

300 believe that their error is correct: Errors committed with high confidence are corrected more readil