ライフサイエンスコーパス: commit to

1 n and this enables mesodermal progenitors to commit to a blood fate.

2 tings, it is generally assumed that subjects commit to a choice at the end of the stimulus stream.

3 s performing a direction discrimination task commit to a choice when the accumulated evidence reaches

4 Decisiveness is the ability to commit to a decision quickly and efficiently; in contras

5 o remain uncommitted, generate precursors or commit to a differentiated fate.

6 te decision must be made, namely, whether to commit to a form of programmed cell death or to make the

7 , RUNX1(+) FGRS-transduced endothelial cells commit to a haematopoietic fate, yielding rEC-HSCs that

8 l and mesodermal cells to enable mesoderm to commit to a hematopoietic fate.

9 eracting with platelets, Ly6C(low) monocytes commit to a meticulous patrolling of the endothelial wal

10 As cells commit to a new cycle, G1 CDK activity (Cln/CDK) inhibit

11 Cells that mutate or commit to a specialized function (differentiate) often u

12 r mechanism by which neural progenitor cells commit to a specified lineage of the central nervous sys

13 r time from feedback but are also allowed to commit to a strategy at any time, eliminating all other

14 orrect epiphany) but not always of those who commit to a suboptimal strategy or who do not commit at

15 nt naive cells receive antigenic signals and commit to a T helper (Th) pathway, the genome-wide conta

16 ing, updating and deleting records by making commits to a git repository.

17 enewing divisions in which one daughter cell commits to a specific fate while the other retains the m

18 rreversible epigenetic changes, cells become committed to a B-blast fate <12 days post-infection and

19 ached a stereotyped level before the monkeys committed to a decision.

20 onfer macrophage phenotypes on cells already committed to a different lineage, but how it overcomes t

21 progenitors in which Notch is activated are committed to a dorsal aorta fate.

22 e onset of proneural gene expression and are committed to a given fate very early; (2) in contrast, t

23 onmuscle invasive bladder cancer (NMIBC) are committed to a lifetime of invasive procedures and poten

24 These muscle progenitors committed to a myogenic program, but were inhibited from

25 ess collier, a marker for post mitotic cells committed to a neural fate, while they are still situate

26 proliferating neuronal progenitor cells that committed to a neuronal lineage in the undamaged retina.

27 iod of antigenic stimulation, T cells become committed to a program of autonomous expansion and diffe

28 C1 pathway and help ensure that cells remain committed to a quiescent state under suboptimal conditio

29 As a consequence we are committed to a sea-level rise of approximately 2.3 m deg

30 cantly enriched by the introduction of nodes committed to a single opinion.

31 ny times at room temperature before becoming committed to a slow, irreversible forward transition to

32 es demonstrated that some germ cells are not committed to a sperm or oocyte cell fate, even in adults

33 ls can acquire sexual identity without being committed to a sperm or oocyte cell fate.

34 rentially replicates in host cells that have committed to a stress response.

35 Consistent with a role in committing to a categorical choice at the end of the evi

36 red in the number of draws required prior to committing to a decision, but not in decision accuracy.

37 favour of the different alternatives before committing to a decision.

38 e images were repeated, and more cautious in committing to a definitive answer.

39 ough multiple rounds of cell division before committing to a new fate.

40 The strong trade-off also means that committing to a particular lifestyle (being consistent)

41 The challenge is to commit to achieving adequate lengths of stay in low- and

42 CR scanning for antigen before the T cell is committed to activation.

43 ASCO is committed to addressing the needs of sexual and gender m

44 ram that determines the number of precursors committing to adipocyte differentiation, the maintenance

45 analysis of these MSCs showed that they were committed to adipocytic differentiation, but unable to t

46 t cells within this equivalence group become committed to alternative O or P developmental pathways i

47 These condensations commit to an osteogenic identity and suppress chondrogen

48 at enable a retinal progenitor cell (RPC) to commit to an RGC fate have not been identified.

49 DeltaNp63-null keratinocytes are capable of committing to an epidermal cell lineage, but are likely

50 ment of germ cells during fetal life as they commit to, and prepare for, oogenesis or spermatogenesis

51 These precursor cells commit to apoptosis-like death under the toxic condition

52 ach other in check until the correct time to commit to apoptosis.

53 g environment cannot be reestablished, cells commit to apoptosis.

54 vision despite the presence of anti-CD4, are committed to apoptosis.

55 reversible binding, tumor cells are rapidly committed to apoptosis/cell death after exposure to b-AP

56 f any, specific interactions are required to commit to association.

57 ion, particularly at a checkpoint before RFC commits to ATP hydrolysis.

58 Nr2e3 expression in photoreceptor precursors committed to be rods (driven by the Nrl promoter) could

59 ng via trans-potentiation of Notch in a cell committed to become a sib.

60 tion increased as common myeloid progenitors committed to become granulocyte-macrophage progenitors a

61 In BMMs committed to become osteoclasts by RANKL treatment, Saa3

62 l of DC ontogeny indicates that pre-cDCs are committed to become terminal conventional DCs (cDCs).

63 T1 B cells expressing surface ADAM10 were committed to becoming MZB cells in vivo, whereas T1 B ce

64 Preadipocytes are fibroblastoid cells committed to becoming round lipid-laden adipocytes.

65 30 h poststarvation, 10-fold more cells were committed to becoming sonication-resistant spores, and c

66 flammatory dynamics caused simulations to be committed to "better" vs. "worse" outcomes by 4 days of

67 ollaboration comprises three global partners committed to capturing, preserving and providing compreh

68 lly and to develop early-stage investigators committed to careers in outcomes research.

69 adjudicate the decision of whether or not to commit to cell death, but also release toxic proteins cu

70 ASCO is committed to collaborating with the diverse community of

71 vs 3.7%, P < 0.001) and were less frequently committed to completing their surgical training (P < 0.0

72 ause ASCO is a professional oncology society committed to conquering cancer through research, educati

73 Individuals requesting others to commit to cooperate (proposers) incur a cost, while thei

74 r cooperation by altering the resources they commit to cooperative interactions.

75 omoted degeneration locally in axons as they committed to degenerate.

76 tion because substrates must be irreversibly committed to degradation before Rpn11 acts.

77 naling complex is formed well before neurons commit to die, consistent with an early role in death si

78 -10, also inhibited p53R2 cleavage in cells committed to die via the extrinsic death receptor pathwa

79 LD biogenesis has a protective role in cells committed to die.

80 pair/remodelling of many tissues, where MSCs commit to different lineages dependent on the cues in th

81 ayer and become rod precursor cells that are committed to differentiate into rods.

82 overy has been that mammary epithelial cells commit to differentiated lineages using the same signall

83 ) are generated by progenitor cells that are committed to differentiating into myelin-forming cells o

84 ia of low calcium concentration, but rapidly commit to differentiation at calcium concentrations >0.0

85 at p63 is required to maintain growth and to commit to differentiation by two distinct mechanisms.

86 How they leave the progenitor state and commit to differentiation is largely unknown, in part be

87 ulated when oligodendrocyte progenitor cells commit to differentiation.

88 ylation of key genes and helping progenitors commit to differentiation.

89 ulations restrict the ability of ES cells to commit to differentiation.

90 g degree of flexibility, with cells normally committed to differentiation able to recover stem cell c

91 uired for neoblasts to produce progeny cells committed to differentiation in order to control tissue

92 ll self-renewal capacity, while the other is committed to differentiation.

93 must attain a critical cell size at Start to commit to division, the large size of ccr4 delta cells i

94 studies demonstrate that neural progenitors committed to dopaminergic fate survive and integrate bet

95 occur as common lymphoid progenitors become committed to each of the ILC lineages further underscore

96 that it and the ubiquitylated substrate are committed to each other after binding.

97 In the scientific community committed to ecological housing and building it is refer

98 ng during affinity maturation and as B cells commit to effector cell fates.

99 In contrast, T cells already committed to effector function were resistant to the sup

100 emonstrate that cells with ALDH activity can commit to either endocrine or acinar lineages, and can b

101 PK pathway shows that individual progenitors commit to either fate asynchronously during blastocyst d

102 izont releasing newly formed merozoites, all committed to either continued asexual replication or dif

103 In 2006, China committed to eliminating measles by 2012; to this end, t

104 ing the World Health Organization (WHO), has committed to ending the AIDS epidemic and to ensuring th

105 Urgent action is needed if we are committed to ending the TB epidemic.

106 surrounding cells in the vegetal mass become committed to endoderm through the action of the vegetal

107 pressing cells showed an enhanced ability to commit to endothelial lineages in mosaic embryos.

108 lant providers, policy-makers and donors are committed to ensuring that prospective donors provide ad

109 The JTFPP is committed to ensuring that the practice parameters are b

110 The Joint Task Force is committed to ensuring that the practice parameters are b

111 differentiation requires a balancing act to commit to epithelial fate while inhibiting both progenit

112 National Human Genome Research Institute is committed to establishing foundational approaches to stu

113 from these centers, updated from 13 centers committed to EVAR treatment whenever possible and includ

114 Public health is committed to evidence-based practice, yet there has been

115 trate, the extrahelical complex is not fully committed to excision.

116 ped IL-17F reporter mice that identify cells committed to expression of IL-17F and IL-17A.

117 ine vertebrate species and have a further 16 committed to extinction by 2050.

118 -24%, resulting in 5-9% of species becoming "committed to extinction," significantly fewer than other

119 to processing, so that all cleaved RNAs are committed to faithful modification.

120 ltivar 30-35 Mya after the first attine ants committed to farming.

121 ter the developmental path of meiosis do not commit to finishing meiosis until after prophase I and t

122 eriments show that these mutants are rapidly committed to folding to the native state, although they

123 les/pro-basal bodies are multipotent and not committed to form either a 9+2 or 9+0 axoneme.

124 We excluded patients not committed to full respiratory support.

125 lls (AGSCs) self-renew (Thy1(+) enriched) or commit to gametogenesis (Kit(+) enriched).

126 g embryonic development and are irreversibly committed to gametogenesis.

127 (in older juveniles) abundant spermatogonia committing to gametogenesis (high KIT(+)).

128 ains unknown when and how progenitors become committed to generate such subtypes.

129 tiate into a megaspore mother cell, which is committed to giving rise to the female germline.

130 genously synthesized NO and the cells become committed to glucose and aerobic glycolysis for survival

131 Cells committed to growth arrest and shmoo formation exhibited

132 World governments have committed to halting human-induced extinctions and safeg

133 tion toward and away from the DNA end, which commits to HR.

134 abilized as the consensus site nucleotide is committed to hydrolysis.

135 ositive regulation of IgE synthesis on cells committed to IgE synthesis.

136 ereas Ly6C(lo)TLR2(hi) monocytes were mainly committed to IL-10 and TNF-alpha production during T. cr

137 T17 cells are a subset of gammadelta T cells committed to IL-17 production and are characterized by t

138 China needs to be committed to implementing effective measures to promote

139 rimary health care that all stakeholders are committed to implementing, attention to district managem

140 Society of Clinical Oncology (ASCO) has been committed to improving cancer outcomes through research

141 rican Society of Clinical Oncology (ASCO) is committed to improving cancer prevention, diagnosis, and

142 The ACP remains committed to improving care for patients throughout and

143 The American Heart Association is committed to improving the health of all Americans throu

144 lymphoid progenitors, which are subsequently committed to innate lymphoid lineages in the alpha-lymph

145 raphic dispersion, number of ASCs each state committed to inspect, and relative cost per inspection.

146 , we found that human podocytes in vitro are committed to internalizing albumin through a receptor-me

147 The Canadian government recently committed to introduce legislation to restrict the comme

148 lineage pattern means a given blastomere is committed to its specific fate, indicative of mosaic dev

149 n the science of autoimmunity and the people committed to its study.

150 unity evolving around this workbench, we are committed to keep the workbench up-to-date for future st

151 the brain's language system, are not in fact committed to language processing, but may function as a

152 ASCO is committed to leading efforts toward the improvement of c

153 dly satisfy task demands without necessarily committing to learning, as the relative permanence of le

154 ng medical professional oncology society, is committed to lessening the burden of cancer and as such

155 e (UPR) is an ancient signaling pathway that commits to life-or-death outcomes in response to proteot

156 ry esophageal pH/impedance monitoring before committing to lifelong PPIs to help distinguish GERD fro

157 rogenitor stem cells, which may have already committed to lineage despite maintaining hallmarks of pl

158 Thus, tissue renewal programs are not committed to maintain cellular equilibrium; stem cells c

159 hieving these goals is the financing that is committed to maintaining biodiversity; however, financin

160 e European Bioinformatics Institute (EBI) is committed to making data readily accessible to the commu

161 al quiescent cells to be precursors that are committed to mature into differentiated secretory cells

162 All 6 World Health Organization regions have committed to measles elimination, and 5 have set a targe

163 edirect the NSCs to produce cellular progeny committed to MEC fates.

164 are returned to rich medium after they have committed to meiosis, the transcript levels of most meio

165 to develop a guideline that individuals can commit to memory easily and act on straightforwardly at

166 Cells commit to mitosis by abruptly activating the mitotic cyc

167 the response to DSBs once cells have already committed to mitosis.

168 ryogenesis, cells must exit pluripotency and commit to multiple lineages in all germ-layers.

169 uration of time that viewers were willing to commit to narrative videos.

170 ural tissue, but also tissue that is not yet committed to neural fates.

171 hey may originate from cells at least partly committed to neuronal lineage.

172 ellular redox partners that are not normally committed to NO production.

173 ntend to leave nursing and more likely to be committed to nursing.

174 imulation (signal 2), resting CD4(+) T cells commit to one of a variety of functionally and molecular

175 Cell lineages of the early human gonad commit to one of the two mutually antagonistic organogen

176 However, after the cell commits to one pathway or the other, phage DNA movement

177 c research into open scientific research and commit to Open Science principles.

178 Interventional cardiologists should be committed to optimal stent choices and techniques of imp

179 ) increased the participants' willingness to commit to organ donation themselves, donate the organs o

180 However, characterization of PDL stem cells committed to osteoblast/cementoblast (O/C) differentiati

181 hat are resistant to RANK downregulation and committed to osteoclast formation, even though they reta

182 fully understanding how and why immune cells commit to particular metabolic fates and in elucidating

183 We demonstrated that human podocytes are committed to performing endocytosis via a receptor-media

184 ld be expressed only in Otx2+ cells that are committed to photoreceptor fate.

185 themselves from MZ B cells, which uniformly commit to plasma cell differentiation.

186 interleukin-6 (IL-6) only regulates B cells committed to plasma cells in response to T-dependent (TD

187 of country and global progress; Countdown is committed to playing its part in this effort.

188 As MPPs commit to pre-B cells, a predominantly demethylating phe

189 de 0 to 1 in the infarct-related artery, and committed to primary percutaneous coronary intervention,

190 Thus, individual Th cells commit to produce distinct amounts of a given cytokine,

191 troke Association is uniquely positioned and committed to promoting the adoption of comprehensive wor

192 nTh17 cells are thymically committed to promptly produce large amounts of IL-17 and

193 s driven MPA establishment, with 193 parties committed to protecting >10% of marine environments glob

194 roblem, about 200 governments worldwide have committed to protecting 10%-20% of national coastal mari

195 Clinical Virology recognize that the FDA is committed to protecting patients.

196 for the global eradication of polio and has committed to provide an additional $35 million each year

197 Being committed to providing continuous support to the scienti

198 ar whether academic surgical departments are committed to providing education and awareness of the ap

199 a state of de novo protein synthesis before committing to pyroptosis.

200 give rise to a long-lived memory population committed to reactivation of the Th2 cytokine gene expre

201 he sham group (mainly because they could not commit to receiving treatment every week).

202 switch that dictates whether CD8(+) T cells commit to recirculating or tissue-resident memory popula

203 i results in up to 40% of all CD8(+) T cells committed to recognition of the dominant TSKB20 and subd

204 While the UK has committed to reduce CO2 emissions to 80% of 1990 levels

205 s Initiative is an international partnership committed to reducing measles deaths worldwide and is le

206 The American Society of Clinical Oncology is committed to reducing the impact of obesity on cancer an

207 Countries in the Indian subcontinent have committed to reducing the incidence of kala-azar, a clin

208 allowed reconstructive urologists to remain committed to rehabilitating the lower urinary tract avoi

209 ricytes (MPs), which are resident stem cells committed to reparative angiomyogenesis.

210 e-saving compound by special interest groups committed to repealing environmental regulations.

211 nothing mode, such as bristle worms: females committed to reproduction spend roughly half their body

212 ognate aminoacyl-tRNAs were considered to be committed to ribosomal protein synthesis through their a

213 2011, provides the rare political moment to commit to scaling up international, regional, and nation

214 s, a terminal UPR program ensures that cells commit to self-destruction.

215 A small proportion of these parasites commits to sexual development to mediate mosquito transm

216 these functional centers is a checkpoint for committing to spacer removal.

217 alth through their ability to self-renew and commit to specialized effector cells.

218 isplay inflammatory and resident subsets and commit to specific functions in atherogenesis.

219 tem cells that were previously thought to be committed to specific lineages.

220 ed sequential events at promoters once cells commit to spermatocyte differentiation.

221 The decision to commit to spermatogenic differentiation coincides with t

222 held in close proximity and the pre-mRNA is committed to splicing.

223 strand breaks, demonstrate >90% of cells are committed to SSA and show that the Rad22(Rad52) repair p

224 h poststarvation, some rod-shaped cells were committed to subsequent shape change and to becoming son

225 enough information or data are available to commit to such long multistep syntheses.

226 reported, and all participating centers have committed to support their consecutive experience with t

227 WHO is committed to supporting country, global, regional, and n

228 ed in patient care and clinical research, is committed to supporting oncologists in their wide-rangin

229 Regulatory T cells (Tregs) are committed to suppressive functions.

230 le white cells well before they irreversibly commit to switching.

231 region of the lens epithelium in which cells commit to terminal differentiation.

232 alling promotes TG activity in keratinocytes committed to terminal differentiation by direct inductio

233 xpress the transcription factor KLF4 and are committed to terminal differentiation.

234 T cell progenitors usually commit to the alphabeta lineage upon the expression of a

235 ats1/2 forces hepatoblasts or hepatocytes to commit to the biliary epithelial cell (BEC) lineage.

236 ol when and how multipotent progenitor cells commit to the desired cell fate.

237 gene 1 activation and failure of T cells to commit to the effector lineage.

238 em cell or the committed progenitor level to commit to the megakaryocyte lineage, supporting the exis

239 Many cells immediately commit to the next cell cycle by building up CDK2 activi

240 nts, and pupillary responses of subjects who commit to the optimal strategy (correct epiphany) but no

241 uired for neural crest-derived mesenchyme to commit to the osteogenic pathway and that both Indian he

242 thelial cells in the adult pancreas that can commit to the pancreatic lineage following proliferation

243 otch signals are required for progenitors to commit to the T cell lineage and necessary for their pro

244 In the thymus, hematopoietic progenitors commit to the T cell lineage and undergo sequential diff

245 rs relinquish competence for other fates and commit to the T cell lineage by turning on Bcl11b, which

246 How naive CD4(+) T cells commit to the T helper type 2 (T(H)2) lineage is poorly

247 (reg) cell subset is comprised of cells that commit to the T(reg) lineage by upregulating the transcr

248 Th17 cells, the ability of CD4(+) T cells to commit to the Th17 lineage, and the ability of committed

249 Conversely, bone-resident cells committed to the adipocytic lineage inhibit hematopoiesi

250 es and allowed NIH 3T3 fibroblasts to become committed to the adipose lineage by bone morphogenetic p

251 The last decade has seen tremendous effort committed to the annotation of the human genome sequence

252 Sixth, Kraepelin was committed to the application of the medical disease mode

253 transcription factors EBF and Pax5, were not committed to the B cell fate.

254 ity of Tcf21-expressing epicardial cells are committed to the cardiac fibroblast lineage prior to ini

255 rize the cardiomyoblast intermediate that is committed to the cardiomyocyte fate, and we characterize

256 phalanx-forming cell lineage is subsequently committed to the cartilage lineage; the fate of these ce

257 ized in vitro of a stand-alone enzyme solely committed to the catalysis of a [4+2] cycloaddition reac

258 ese include the existence of networks deeply committed to the cause, the potential to link with globa

259 ed derepression of CD4 expression in T cells committed to the CD8(+) lineage without affecting the ex

260 itors of the limb bud, i.e. in cells not yet committed to the chondrocyte lineage.

261 plication in diploid Bacillus subtilis cells committed to the developmental pathway leading to format

262 The National Ministry of Health has committed to the elimination-rather than control-of chol

263 hereas Pax6(+) progenitors were irreversibly committed to the endocrine fate, we discovered that Ngn3

264 s have been characterized to date-one solely committed to the endothelial lineage and the other carry

265 of mental health clinicians and physicians, committed to the evaluation and management of transplant

266 e found that CD27(+) gammadelta T cells were committed to the expression of Ifng but not Il17, wherea

267 xpressing CD4(-)CD8(-) progenitors that have committed to the gammadelta fate from those that have no

268 se that express CD73 remain CD4(-)CD8(-) and committed to the gammadelta fate.

269 ese Nestin-expressing progenitors (NEPs) are committed to the granule neuron lineage.

270 enhancer was deleted after cells had already committed to the helper T-cell lineage, CD4 expression r

271 ZF)-expressing ILC precursor (ILCP) strictly committed to the ILC1, ILC2, and ILC3 lineages.

272 re population of cells in adult mouse blood, committed to the mast cell lineage.

273 ABCs), that were distinct from ASCs and were committed to the MBC lineage.

274 mice, which express Cre recombinase in cells committed to the megakaryocytic lineage, to Srf(F/F) mic

275 Cells committed to the MK lineage undergo mitotic proliferatio

276 es the differentiation and function of cells committed to the monocyte-derived dendritic cell (DC) li

277 ress KIR, and a novel subpopulation of cells committed to the NK-cell lineage was defined.

278 entiation into oligodendrocytes but remained committed to the oligodendrocyte lineage.

279 C3H10T1/2 and human bone marrow cells can be committed to the osteogenic lineage by DPP.

280 Most governments have committed to the set of Sustainable Development Goals es

281 ted here show that once epithelial cells are committed to the Sox2-positive airway epithelial cell fa

282 otes and archaea, cis-PT is the first enzyme committed to the synthesis of dolichyl phosphate, an obl

283 Early thymic progenitors (ETPs) are not committed to the T-cell lineage, as demonstrated by both

284 lear whether there are CD4(+) memory T cells committed to the Tfh cell lineage after antigen clearanc

285 Outside cells become committed to the trophectoderm at the blastocyst stage t

286 double-positive cells, and silenced in cells committing to the CD4(+) single-positive (SP) lineage, r

287 nd direct testing on NHP-induced GVHD before committing to the intensive NHP studies that are being i

288 o Th17 cells, although they are competent in committing to the other effector lineages.

289 at differentiated cells are not irreversibly committed to their fate.

290 joint progenitor cells are unable to remain committed to their specified cell fate in mutant mice wi

291 tion schema demands that those who are truly committed to their work will make it the central or sole

292 Open complexes are committed to transcription, suggesting that regulation l

293 h2 cells with IL-4 locus activation remained committed to transcriptional competence of Th2 cytokine

294 The inability to commit to ultimate decisions, for example, patients unab

295 The ATS and ERS commit to undertake actions that will improve access to

296 and the Proteomics Standards Initiative have committed to using FuGE as the basis for defining their

297 nd needs to be thoroughly evaluated prior to committing to validating a DBS assay.

298 were designated iVPCs because they remained committed to vascular lineage and could differentiate in

299 that parasitic angiosperms, which naturally commit to virulence through the growth of new organs, de

300 , and all five national governments recently committed to work nationally, regionally, and globally t