ライフサイエンスコーパス: commitment to

1 by allowing motor activity to occur before a commitment to a choice and demonstrated that the propose

2 ition between motor plans and determine when commitment to a choice is made.

3 tations reflect, to some extent, a tentative commitment to a choice.

4 ahlbaum, Hecker, and Kraepelin shared both a commitment to a clinical research agenda for psychiatry

5 s) that occasionally happen before the final commitment to a decision [8-10].

6 ion in high-salinity environments preventing commitment to a developmental program that it cannot com

7 s that can block the transition from lineage commitment to a differentiating state in myoblasts and o

8 ssion of Atoh1 does not absolutely result in commitment to a HC fate.

9 ing legumes may be driven by an evolutionary commitment to a high N strategy, by higher N availabilit

10 A renewed commitment to a more forward-looking, flexible yet integ

11 mulation of evidence "scores" over time, and commitment to a particular alternative once its scores r

12 Developmental commitment to a particular blood-cell lineage is gradual

13 hymal stem cells (BMMSCs) by dictating their commitment to a pro-neural lineage.

14 cal steps of recombination, signifying early commitment to a productive reaction path.

15 A decision is a commitment to a proposition or plan of action based on i

16 This hastens the commitment to a single lamellipodium initiated in respon

17 comparison in abstract goods-space prior to commitment to a specific action.

18 In this study, we show that commitment to a stable lineage occurred during early sta

19 rn coincident with increasing maturation and commitment to a T cell fate.

20 The commitment to achieve these targets should be celebrated

21 to promote their group through non-rational commitment to actions independently of likely risks and

22 issue of access, despite the UN's political commitment to address non-communicable diseases and ensu

23 ents should be held accountable for their UN commitments to address the crisis.

24 ctives at local scales while aiding national commitments to addressing ongoing global challenges.

25 ated receptor gamma expression that controls commitment to adipogenesis and is repressed by Zfp521.

26 lation of transcription factors critical for commitment to adipogenesis.

27 XXX cells act as a source of DA, which, upon commitment to adult development, is amplified and propag

28 greater national and international financial commitment to advancing ecosystem services and natural c

29 After exclusion of patients without commitment to aggressive management, 181 patients in the

30 le signaling through CD137; however, initial commitment to all M cell lineages is B lymphocyte and CD

31 ontribution be acknowledged through a shared commitment to alleviate ethically problematic aspects of

32 This checkpoint prevents irreversible commitment to an effector fate until a critical threshol

33 reater attention to rare variation, an early commitment to an ethical inclusion of indigenous communi

34 generally believe they confirm the patient's commitment to an operation and all ensuing postoperative

35 gain (for increasing) or both (in variable) commitment to an opinion.

36 f bone marrow cells to bone surfaces and the commitment to an osteogenic lineage of these cellsin viv

37 short hairpin RNAs) and observed an enhanced commitment to and acceleration of erythroid differentiat

38 Commitment to and completion of sexual development are e

39 We show that the commitment to apoptosis is controlled by phosphorylation

40 p53 killer (a p53 phosphoform which promotes commitment to apoptosis) in cells characterized by high

41 logy, including stress response, metabolism, commitment to apoptosis, and development.

42 oapoptotic signal from reaching the point of commitment to apoptosis.

43 proteins and, by extension, control cellular commitment to apoptosis.

44 ng enrichment of b-AP15 in cells and a rapid commitment to apoptosis/cell death are factors that like

45 us, c-Myb does not appear to be required for commitment to B cell differentiation but is crucial for

46 ing active mutants showing decreased forward commitment to beta-lactam cyclization.

47 The strong UK Government commitment to biomedical research has not been translate

48 Thus, we conclude that Zeb2 regulates commitment to both the cDC2 and pDC lineages through rep

49 ocus on human neurobiology, and a continuing commitment to build a diverse, innovative neuroscience w

50 Commitment to building mental health treatment capacity

51 on of environmental bacteria by modulating a commitment to bursts of fast pumping.

52 tiated KCs, we examined the reversibility of commitment to Ca(2+)-induced differentiation.

53 Together with their spontaneous commitment to cardiac and angiogenic differentiation, tr

54 dence of donor-acceptor distance and forward commitment to catalysis along with steady state and sing

55 isotope effect for heavy F159Y PNP came from commitment to catalysis experiments.

56 low product release, and that tyrosine has a commitment to catalysis of 0.45.

57 with absence of external forward and reverse commitments to catalysis, and the chemical step of CH bo

58 n of reaction kinetics, isotope effects, and commitment-to-catalysis based on experiment and theory s

59 Shortly after commitment to CD4 SP cell lineage, monovalent repressive

60 ion and processing of the enzyme and driving commitment to cell death.

61 unmasked a sharp TCR signaling threshold for commitment to cell division both in vitro and in vivo.

62 In budding yeast, commitment to cell division corresponds to activating th

63 the bulk of the G1/S regulon, ensuring that commitment to cell division occurs before large-scale ch

64 target of rapamycin, passage through START (commitment to cell division), and an intact actin cytosk

65 hase before Start, the point of irreversible commitment to cell division.

66 l health community should show its steadfast commitment to child survival by amassing knowledge and e

67 tside a woman's awareness and control (e.g., commitment to child's health or age).

68 ionally, particularly at a time of uncertain commitment to climate change agreements at the national

69 y angiography and they called for a national commitment to completion of randomized trials, their cal

70 We highlight the many drawbacks of a commitment to compositional representations and describe

71 leadership development, including individual commitment to continued self-development.

72 l helminths in the context of renewed global commitment to control or eliminate neglected tropical di

73 and a broad interest that came from a strong commitment to curiosity-driven research, a commitment he

74 ore MTOC polarization, and did not require a commitment to cytotoxicity.

75 n 48 h of cytokine exposure, and peaked upon commitment to DC growth at 72 h.

76 Commitment to death via the mitochondrial apoptotic path

77 y it influences substrate residency time and commitment to degradation.

78 sparent accountability structures, political commitment to delivery of improvements in child health a

79 ssociated with further oxidation of 5hmC and commitment to demethylation through 5fC.

80 encing of malaria cultures undergoing sexual commitment to determine the transcriptional changes indu

81 esults indicate AP2IX-9 restricts Toxoplasma commitment to develop the mature bradyzoite tissue cyst.

82 Commitment to development was investigated by adding nut

83 By transiently priming cells for commitment to different lineages, these fluctuations are

84 Commitment to differentiate into specific lineages requi

85 signaling pathways that control the overall commitment to differentiate.

86 resulting from CE polarity are required for commitment to differentiated somatic cell fates.

87 ble bistable switch, and we map the point of commitment to differentiation after exposure to cis-acon

88 These data indicate that commitment to differentiation does not prohibit cells fr

89 ytes by elaborating Notch signaling, and ISC commitment to differentiation into EE cells by regulatin

90 sp of hetR, pattern formation, the timing of commitment to differentiation, and the number of cells t

91 is results in the activation of Gad8 and the commitment to differentiation.

92 f a common precursor that had not made prior commitments to diversity.

93 Commitment to division corresponds precisely to activati

94 estable interactions critical for early G2/M commitment to division.

95 ss to be a deceased organ donor (measured as commitment to donate and/or intention to donate).

96 ILC3 subsets, the transcriptional control of commitment to each ILC lineage is incompletely understoo

97 tion (Paper 2 of this Series) and increasing commitment to early childhood development (Paper 1 of th

98 xamine recent scientific progress and global commitments to early childhood development.

99 College of Cardiology is recognized for its commitment to education and quality and a commitment to

100 ptional factor Prospero (Pros) regulates ISC commitment to EEs.

101 Commitment to either fate is determined during the prece

102 the use of these methods does not require a commitment to either gene-like cultural inheritance or t

103 s from tissues are likely to determine their commitment to either lineage and affect the balance betw

104 ween transcriptional regulators critical for commitment to either lineage.

105 stinct memory CD4(+) T cell populations with commitment to either Tfh- or Th1-cell lineages.

106 mechanistic node at the branch point between commitment to either Treg or Th17 lineages.

107 loyee satisfaction related to organizational commitment to employee safety and impact on job satisfac

108 y experienced by staff in reconciling agency commitments to empowerment with the reality of their cli

109 here is still a major shortfall in political commitments to enhance the coverage and effectiveness of

110 Although commitment to epidermal differentiation is generally con

111 program of signaling pathways that determine commitment to epithelial and mesenchymal phenotypes.

112 display exquisitely precise, cell-autonomous commitment to epithelial differentiation consistent with

113 Its unwavering commitment to eradicate polio has been vital to the succ

114 made 14 recommendations that require ongoing commitments to eradication of infectious disease and inc

115 ional scientific research, but also a strong commitment to excellence among all healthcare providers,

116 ins and Cbfbeta restrict granulocyte lineage commitment to facilitate multilineage hematopoietic diff

117 oured, it is unknown whether and how early a commitment to final fate is made.

118 d that 61% of the countries that have made a commitment to FP2020 exceeded pre-FP2020 expectations fo

119 We estimated the commitment to future emissions and warming represented b

120 anus or other Saccharomyces species, delayed commitment to galactose metabolism until glucose was exh

121 ding of the molecular mechanisms involved in commitment to gametocyte formation is extremely limited,

122 The data suggest a mechanism of commitment to gametocytogenesis in Plasmodium consistent

123 elating thymic TCRgammadelta signalling with commitment to gammadelta effector fates.

124 epend on all of us having a vision of, and a commitment to, gender equality to make violence-free liv

125 d through many adaptive steps while delaying commitment to genotypic fate, hindering our ability to p

126 (iv) The intervals between the commitment to germinate and CaDPA release were similar f

127 Rates of commitment to germinate and germination of Bacillus subt

128 es of gerD spores were partially due to slow commitment to germinate.

129 hematopoietic precursor cell activation and commitment to granulocyte lineage development.

130 on-relatives and may determine the extent of commitment to group welfare at different intensities of

131 ereby enabling their rapid transcription and commitment to growth.

132 hat retainer medicine obstructs professional commitments to health care access and social justice.

133 species (ROS) serve as a prime signal in the commitment to hematopoiesis in both mammals and Drosophi

134 Strong political and technical commitment to improve equity-sensitive information syste

135 As part of its commitment to improve the cardiovascular health of all A

136 provision of services must include a strong commitment to improve the safety and quality of care.

137 provision of services must include a strong commitment to improve the safety and quality of care.

138 orders as a core development issue requiring commitments to improve access to care, promote human rig

139 Medical professionalism requires a commitment to improving access to care, and physicians c

140 n addition to the AHA's historic and ongoing commitment to improving cardiac arrest care and outcomes

141 French Hepato-Pancreato-Biliary-centers made commitment to include all patients undergoing elective h

142 the IOM report, the AHA is announcing 4 new commitments to increase cardiac arrest survival: (1) The

143 The survey included commitment to intensive care medicine training, teaching

144 e molecular events underlying the parasite's commitment to invasion are not well understood.

145 and implement national plans and make budget commitments to invest in actions by multiple sectors to

146 ulus' expected hedonic value is altered by a commitment to it.

147 gnals reflected two decision biases-to defer commitments to later, and to weight potential losses mor

148 oaches used to assess faculty competence and commitment to lifelong learning across missions.

149 ally express differentiation markers showing commitment to liver development, even under conditions t

150 ase after PH was involved in the priming and commitment to liver regeneration, whereas the subsequent

151 f disease, and a woman's preferences, with a commitment to long-term follow-up.

152 ng such progress was the Government's strong commitment to long-term strategies to ensure access to d

153 , access to care and insurance coverage, and commitment to long-term treatment and medication complia

154 ts, and multilateral organizations have made commitments to meeting future agricultural demand sustai

155 at the Itga2b Iocus, we find that following commitment to megakaryocyte differentiation, the H3K27 d

156 , point-of-care guidance with ASCO's abiding commitment to methodologic rigor in guideline developmen

157 plays a critical role in regulating cellular commitment to mitochondrial apoptosis.

158 wn as mitosis-promoting factor (MPF), drives commitment to mitosis.

159 e orientation after mitotic entry and before commitment to mitotic exit.

160 argue that autonomous timing allows a trial commitment to multicellularity that external signals cou

161 ancer cells expressing TGF-beta1 resulted in commitment to myofibroblasts.

162 become IPC NBs and survive, indicating that commitment to NB fate nullified the requirement of Egfr

163 l Heart, Lung, and Blood Institute's (NHLBI) commitment to new and established investigators as outli

164 ctors of intent to leave nursing and a lower commitment to nursing among newly licensed RNs.

165 demand were significantly related to a lower commitment to nursing and a greater intent to leave nurs

166 f the hospital work environment affect their commitment to nursing.

167 ns are part of the same folding funnel, with commitment to one structure or the other occurring only

168 e their expected returns by making momentary commitments to one or other activity.

169 With a commitment to open access and innovation in peer review,

170 We aimed to determine caregivers' commitment to OPV in districts of Afghanistan at high ri

171 e feeding might be influenced by an animal's commitment to other behaviors.

172 al genes, and that stiffness does not impact commitment to particular neuronal subtypes.

173 come another chronic disease, where lifelong commitment to pharmacologic control is the paradigm.

174 mediated by computations that make implicit commitments to physical and mathematical principles gove

175 ack in the initiator module and irreversible commitment to positive feedback in the executioner modul

176 by which surgeons negotiate with patients a commitment to postoperative care before undertaking high

177 ed response to HTOR that invokes a universal commitment to prevent, protect, and suppress its continu

178 Wnt families are key mediators of stem cell commitment to produce preadipocytes.

179 xpressed a lower program fit (P = 0.008) and commitment to program completion (P = 0.037).

180 g decades, the way the BCL-2 family controls commitment to programmed cell death has been greatly elu

181 The commitment to programmed cell death via apoptosis is lar

182 nslocation is required to protect cells from commitment to programmed death.

183 eshold of TCR signaling that is required for commitment to proliferation, after which T cells are abl

184 oliferative state, as well as the subsequent commitment to proper terminal differentiation.

185 cing economic development with international commitments to protect biodiversity is a global challeng

186 nd OPS-dependent signals determines cellular commitment to protophloem sieve element fate, with OPS a

187 The commitment to provide palliative care for all people wit

188 'Hopital Bon Sauveur (HBS) have longstanding commitments to provide equitable surgical care in rural

189 article serves as the organizations' formal commitment to providing a foundation of HVC education on

190 y major corporations and countries have made commitments to purchase or produce only "sustainable" pa

191 n College of Surgeons, with its century-long commitment to quality improvement, research-based standa

192 ts commitment to education and quality and a commitment to quality metrics that facilitate best pract

193 The pentad residues in Cre enhance commitment to recombination by kinetically favoring the

194 nucleophile, are consistent with a stronger commitment to recombination in the Flp system.

195 There is a global commitment to reduce premature cardiovascular diseases (

196 Given the magnitude of these debts, commitments to reduce emissions and biodiversity loss ar

197 on on Aid Effectiveness represented a global commitment to reform aid practices in order to improve d

198 Successful periodontal treatment requires a commitment to regular lifelong maintenance and may be pe

199 g stem cells undergo self-renewal or lineage commitment to replenish tissue, depending on cross-talk

200 Overall, physicians support the professional commitment to report all instances of impaired or incomp

201 eyed physicians agreed with the professional commitment to report physicians who are significantly im

202 cular biology techniques to demonstrate that commitment to reproductive adult development occurs when

203 ion of DA biosynthesis ensures organism-wide commitment to reproductive development.

204 interested in research than men; women lose commitment to research as their education and training p

205 including whether women with a demonstrated commitment to research succeed at the same rate as male

206 This is in keeping with the commitment to revise and refine the AUC on a frequent ba

207 pf1 to mRNAs precedes a kinetically distinct commitment to RNA decay.

208 on between Nrl and Rorb genes reinforces the commitment to rod differentiation.

209 leaders, peer support, and an organizational commitment to safe, open cultures, may improve safety vo

210 Increased commitment to scaling up best practices could lead to si

211 e of a BLH6-KNAT7 heterodimer that represses commitment to secondary cell wall biosynthesis in interf

212 s part of a regulatory network governing the commitment to secondary cell wall biosynthesis of Arabid

213 ion from flowering to fruit production and a commitment to seed dispersal.

214 GMPs, but instead acts downstream of lineage commitment to selectively control neutrophil and monocyt

215 CLE45(G6T) variant, interferes not only with commitment to sieve element fate but also with the forma

216 ring whether starvation persists and halting commitment to sporulation if nutrients reappear.

217 oth before and during the critical period of commitment to sporulation.

218 more than 1% of bacterial genomes; however, commitment to strand exchange was believed to occur afte

219 n a limited number of practices to reinforce commitment to suicide on the part of recruits.

220 equires vision, persistence, and a long-term commitment to supporting cancer research and training.

221 followed by Japan which had a high relative commitment to surgery within cancer research, followed b

222 His commitment to surgical science and, more importantly, to

223 Commitment to survival or apoptosis within expanding pro

224 be accompanied by organizational leadership commitment to sustaining the lean culture in the laborat

225 rned some of our intuitions strengthened our commitment to testing communication elements whenever po

226 genic risk of cancer, based on an uninformed commitment to the 70-y-old linear no-threshold hypothesi

227 release of haemoprotein into the cytosol and commitment to the apoptotic program.

228 ption factor essential for specification and commitment to the B cell fate.

229 ) before onset of the expression of CD10 and commitment to the B cell lineage.

230 EBF1, in addition to Pax5, is necessary for commitment to the B cell lineage.

231 death rather than impaired proliferation or commitment to the B lineage.

232 indicating that IL-7 can be dispensable for commitment to the B-cell lineage.

233 pocyte precursors (APs) and their subsequent commitment to the beige fat lineage.

234 dermomyotome, but the factors that regulate commitment to the brown adipose lineage are unknown.

235 een MHC class II and TCR/CD4 is required for commitment to the CD4 helper lineage.

236 loop that contributes to lock in the initial commitment to the CD4 lineage during differentiation.

237 Commitment to the CD4 or CD8 lineage is influenced by th

238 ession of unexpectedly few genes accompanied commitment to the CD4(+) or CD8(+) lineage, a similarity

239 )CD8(+) double-positive thymocytes and their commitment to the CD4(+)CD8(-) single-positive stage are

240 The commitment to the cell cycle in the early embryo appears

241 Progressive commitment to the DC lineage also occurs intrathymically

242 c progenitors (CDPs), demonstrate increasing commitment to the DC lineage, as they sequentially lose

243 pid and sustained national and international commitment to the development of appropriate interventio

244 YY1 deletion, Lgr5(+) cells accelerate their commitment to the differentiated population, exhibit inc

245 Upon commitment to the double-negative stage of T cell develo

246 ith Oct4, a stem cell factor that determines commitment to the embryonic lineage, for overlapping bin

247 nerally, these results provide evidence that commitment to the erythroid lineage limits development o

248 sites of occupancy shift dramatically during commitment to the erythroid lineage, vary further during

249 Cdx2, a stem cell factor that determines commitment to the extraembryonic lineage, directly binds

250 According to the prevailing view, commitment to the former lineage, in contrast to the lat

251 etocytes and may represent genes involved in commitment to the gametocyte lineage.

252 engagement in the thymus has initiated their commitment to the gammadeltaT1 lineage.

253 emain poorly defined during neural stem cell commitment to the glial lineage.

254 means of identifying group members, ensuring commitment to the group, facilitating cooperation, and m

255 is an important indicator of a government's commitment to the health of its people, and is essential

256 ic protein 4 (BMP4) is required for mesoderm commitment to the hematopoietic lineage during early emb

257 This effect did not result from premature commitment to the initially dominant target, because a s

258 hancer accessibility was a key mechanism for commitment to the iNKT cell lineage.

259 Commitment to the innate lymphoid cell (ILC) lineage is

260 ineage priming of enhancer elements precedes commitment to the lymphoid or myeloid cell lineages.

261 ferentiation, with initial CD137-independent commitment to the M cell lineage followed by a CD137-CD1

262 Csf1r expression coincides with the earliest commitment to the macrophage lineage, Csf1r-EGFP bone ma

263 ugh beta2-AR, but acquisition of beta1-AR on commitment to the myocyte lineage results in loss of CPC

264 potent modulators of stem cell replication, commitment to the myocyte lineage, and myocyte different

265 in NK cell numbers when added at the time of commitment to the NK cell lineage.

266 We propose that E4bp4 is required for commitment to the NK lineage and promotes NK development

267 through the Valpha14-Jalpha18 TCR instructs commitment to the NKT cell lineage, but the precise sign

268 antagonizing lateral induction and promoting commitment to the non-sensory fate.

269 luencing factors include professionalism and commitment to the nursing profession.

270 g environment, (2) psychological safety, (3) commitment to the organization, (4) senior management su

271 F directs human mesenchymal stem cell (hMSC) commitment to the osteoblast lineage and modulates Wnt/b

272 Together, these results suggest that commitment to the osteoblast lineage is not a requiremen

273 or proliferation, early differentiation, and commitment to the osteoblastic lineage through the selec

274 ies of secretory progenitor cells undergoing commitment to the Paneth or enteroendocrine lineages, wh

275 icate the risks of surgery and express their commitment to the patient's survival.

276 which developmental stage and location final commitment to the pDC lineage occurs.

277 a cascade of ApiAP2 proteins are involved in commitment to the production and maturation of gametocyt

278 the effect of JSY as financial and political commitment to the programme intensifies.

279 As endoscopists continue their commitment to the promise of direct visualization of the

280 threshold to elicit cell death, irreversible commitment to the response, and a time delay that is inv

281 SE cells expressed markers suggesting their commitment to the SE lineage.

282 included the anklet acting as a reminder of commitment to the study (and the agreement to sobriety),

283 cial for T cell development and peaks during commitment to the T cell lineage, midway through the CD4

284 neage choices accompanying specification and commitment to the T cell lineage.

285 Commitment to the T-cell lineage is now shown to depend

286 ion in dividing CD4(+) T cells by regulating commitment to the Th17 differentiation program.

287 lcitriol of mice challenged for EAU impaired commitment to the Th17 lineage, as judged by reduction o

288 nd extrinsic cues that guide development and commitment to the Treg lineage, and the phenotypic and f

289 tmarketing observational cohort study, was a commitment to the US Food and Drug Administration to ass

290 Severing the commitment to this taxonomy would allow Huang & Bargh (H

291 s are, in aggregate, inconsistent with their commitments to this temperature limit.

292 des a molecular memory that ensures faithful commitment to transcriptional programs during mammalian

293 ) new conflict of interest policy reflects a commitment to transparency and independence in the devel

294 r presents a model to assess the strength of commitment to trustworthy research and explores proven q

295 This requires a strong commitment to trustworthy research practices, as well as

296 tries of India, China, and Russia, will be a commitment to tuberculosis control including improvement

297 l tuberculosis community to make a sustained commitment to tuberculosis transmission science.

298 Commitment to ubiquitination is dictated primarily by co

299 both at the bedside as well as in research, commitment to using standardized AKI definitions in orde

300 r number of guidelines while maintaining its commitment to using the rigorous development methods tha