ライフサイエンスコーパス: common myeloid progenitor

1 Granulocytes and monocytes develop from a common myeloid progenitor.

2 c differentiation skewing of multipotent and common myeloid progenitors.

3 s and in granulocyte-monocyte progenitors or common myeloid progenitors.

4 ns of PU.1 expression within flk2- and flk2+ common myeloid progenitors.

5 esent the functional equivalent of mammalian common myeloid progenitors.

6 nitor cells and is not detected on primitive common myeloid progenitors.

7 tors such as common lymphoid progenitors and common myeloid progenitors.

8 where VPA re-activated replating activity of common myeloid progenitor and granulocyte macrophage pro

9 escued the progenitor cell defect, restoring common myeloid progenitor and megakaryocytic-erythroid p

10 cells of the haematopoietic system, such as common myeloid progenitors and common lymphoid progenito

11 ed production of myeloid lineage precursors (common myeloid progenitors and granulocyte myeloid precu

12 on hematopoietic stem cells, differentiating common myeloid progenitors and granulocyte-macrophage pr

13 such as PU.1, C/EBP1alpha, and Gfi-1 in the common myeloid progenitors and granulocyte-macrophage pr

14 opulation assays and defective in generating common myeloid progenitors and granulocyte-monocyte prog

15 lar endothelial cells can differentiate from common myeloid progenitors and granulocyte/macrophage pr

16 recruitment of myeloid precursors, including common myeloid progenitors and granulocytic-monocytic pr

17 near CEBPA overlapped an enhancer active in common myeloid progenitors and influenced its activity.

18 Common myeloid progenitors and megakaryocyteerythrocyte

19 opmental intermediates, the human clonogenic common myeloid progenitors and their downstream progeny,

20 d during the commitment of short-term HSC to common myeloid progenitors and these alterations were pr

21 Furthermore, VCAM-1(+) MPPs gave rise to common myeloid progenitors and VCAM-1(-) MPPs in vivo, i

22 Irf8(-/-) common myeloid progenitors and, unexpectedly, Irf8(-/-)

23 including lineage(-)Sca-1(+)c-kit(+) (LSK), common myeloid progenitor, and granulocyte/macrophage pr

24 nated bone marrow, hematopoietic stem cells, common myeloid progenitors, and bipotent megakaryocyteer

25 xpansion of immature lineage-negative cells, common myeloid progenitors, and granulocyte/macrophage p

26 urified human long-term HSC, short-term HSC, common myeloid progenitors, and megakaryocyte-erythrocyt

27 ocyte-erythrocyte progenitors, a decrease in common myeloid progenitors, and reduced beta-catenin sig

28 Common myeloid progenitors are normally a good source of

29 itor compartment, consisting of depletion of common myeloid progenitors but relative sparing of granu

30 until recently when it was demonstrated that common myeloid progenitors can also give rise to CD8alph

31 normally elevated frequencies and numbers of common myeloid progenitor (CMP) and granulocyte/macropha

32 athogen-associated molecular patterns by the common myeloid progenitor (CMP) and is dependent on type

33 xpressed in hematopoietic stem cells (HSCs), common myeloid progenitor (CMP) cells, as well as in meg

34 e drives classical MDS phenotypes and alters common myeloid progenitor (CMP) differentiation by repre

35 ed that the developmental defect of DCs from common myeloid progenitor (CMP) in Mysm1(-/-) mice is as

36 In Dhh-deficient bone marrow, the common myeloid progenitor (CMP) population was increased

37 which is associated with an increase in the common myeloid progenitor (CMP) population.

38 PP-derived common lymphoid progenitor (CLP), common myeloid progenitor (CMP), megakaryocyte-erythroid

39 uce upstream APC progenitor cells, including common myeloid progenitor (CMP)-Flk2(+).

40 n of lineage-restricted progenitors known as common myeloid progenitors (CMP) and granulocyte-monocyt

41 ch into common lymphoid progenitors (CLP) or common myeloid progenitors (CMP) during this process rem

42 entified that induces the differentiation of common myeloid progenitors (CMP) to megakaryocytes.

43 ulation, but fewer common lymphoid (CLP) and common myeloid progenitors (CMP).

44 (Lin(-)Sca-1(+)c-Kit(+)CD34(+)Flt3(hi)) and common myeloid progenitors (CMPs) (Lin(-)Sca-1(+)c-Kit(+

45 Herein, we found that common myeloid progenitors (CMPs) and granulocyte-macrop

46 t among hematopoietic progenitor stem cells, common myeloid progenitors (CMPs) and granulocyte-macrop

47 ition, PU.1(-/-) fetal liver at e14.5 lacked common myeloid progenitors (CMPs) and granulocyte-macrop

48 nt in other myeloid progenitor compartments [common myeloid progenitors (CMPs) and granulocyte/monocy

49 rs, in addition to significant reductions of common myeloid progenitors (CMPs) and granulocyte/monocy

50 rs of common lymphoid progenitors (CLPs) and common myeloid progenitors (CMPs) and greater than norma

51 ATMIN has an ATM-independent function in the common myeloid progenitors (CMPs) by deletion of Atmin i

52 However, we show PDCs arise exclusively from common myeloid progenitors (CMPs) characterized by low-l

53 Prospectively purified single common myeloid progenitors (CMPs) coexpress myelo-erythr

54 c common lymphoid progenitors and clonogenic common myeloid progenitors (CMPs) in adult mouse bone ma

55 Forced expression of KLF4 in primary common myeloid progenitors (CMPs) or hematopoietic stem

56 However, unexpectedly, the common myeloid progenitors (CMPs) produce significantly

57 Common myeloid progenitors (CMPs) were first identified

58 nitor populations are thought to derive from common myeloid progenitors (CMPs), and a hierarchical re

59 imary mouse hematopoietic stem cells (HSCs), common myeloid progenitors (CMPs), and erythroblasts (ER

60 Reconstitution with common myeloid progenitors (CMPs), common lymphoid proge

61 Id2(+/-) mice revealed that short-term HSCs, common myeloid progenitors (CMPs), erythroid burst-formi

62 nd 6 closely related progenitor populations: common myeloid progenitors (CMPs), granulocyte-macrophag

63 or MPPs, common lymphoid progenitors (CLPs), common myeloid progenitors (CMPs), granulocyte/macrophag

64 The pattern of mutations may differ between common myeloid progenitors (CMPs), granulomonocytic prog

65 y irradiated mice with purified progenitors: common myeloid progenitors (CMPs), megakaryocyte/erythro

66 Common myeloid progenitors (CMPs), the earliest known my

67 nies by hematopoietic stem cells, but not by common myeloid progenitors (CMPs), was severely reduced

68 Ps), common lymphoid progenitors (CLPs), and common myeloid progenitors (CMPs).

69 hat primitive myeloid-committed progenitors (common myeloid progenitors [CMPs]) are efficient precurs

70 actor XIII-A mRNA transcription increased as common myeloid progenitors committed to become granulocy

71 company loss of in vivo myeloid potential as common myeloid progenitors differentiate into common DC

72 the heterochronic factor Lin28b decreases in common myeloid progenitors during hematopoietic maturati

73 We showed that GMPs but not common myeloid progenitors expressed low levels of IL-3

74 Common myeloid progenitors give rise to either megakaryo

75 o exhaustion of the myeloid progenitor pool (common myeloid progenitor, granulocyte-monocyte progenit

76 sorting to isolate hematopoietic stem cells, common myeloid progenitors, granulocyte-macrophage proge

77 and spleen showed proportional expansion of common myeloid progenitors, granulocyte-monocyte and meg

78 and CD8alpha- DCs can arise from clonogenic common myeloid progenitors in both thymus and spleen.

79 ically expressed in myeloid cells, including common myeloid progenitors of hMRP8-AML1-ETO transgenic

80 genitors instead of, as previously proposed, common myeloid progenitors or granulocyte/macrophage pro

81 pose that the common lymphoid progenitor and common myeloid progenitor populations reflect the earlie

82 ates such as common lymphoid progenitors and common myeloid progenitors, recapitulating the steady-st

83 In contrast, lack of Ikaros in the common myeloid progenitor resulted in increased formatio

84 ell populations ranging from the oligopotent common myeloid progenitor stage to terminally differenti

85 low cytometry, of a complementary clonogenic common myeloid progenitor that gives rise to all myeloid

86 myeloid lineages, and that the commitment of common myeloid progenitors to either the megakaryocyte/e

87 -kit(+)) Sca-1(-) cells containing primarily common myeloid progenitors were cultured in vitro withou

88 is characterized by expansion of phenotypic common myeloid progenitors, whereas higher-risk cases re

89 s this effect by up-regulating the number of common myeloid progenitors while inhibiting development