ライフサイエンスコーパス: common site

1 certain whether these ligands recognize this common site.

2 nhibited binding of Zn(2+) and Cd(2+) to the common site.

3 tetrapyrrole and flavin substrate bind at a common site.

4 ggested that they nevertheless compete for a common site.

5 nce affects state dependence of binding to a common site.

6 pines, as would be predicted for action at a common site.

7 E1 transcripts initiate transcription from a common site.

8 hether cyclothiazide and GYKI 53655 act at a common site.

9 itive sodium channels via interaction with a common site.

10 are common, with the forearm being the most common site.

11 Transcripts initiated primarily at a common site.

12 facilities (2,325; 6.1%) were the next most common sites.

13 ons received inhibitory synaptic inputs from common sites.

14 Both mRNAs begin at a common site 1338 bp upstream of the initiation codon, co

15 Although liver was the most common site, 39.5% of patients had nonliver sites, most

16 inal tract, the small intestine was the most common site (44.7%), followed by the rectum (19.6%), app

17 The gingiva was the most common site (60.4%), followed by tongue and tonsil.

18 STAT3 and STAT5 bound to multiple common sites across the locus encoding IL-17.

19 The band 1q21 is among the most common sites affected by chromosomal translocations in l

20 sistent with the two metal ions binding to a common site and with an approximately 30-fold lesser aff

21 steric antagonist and agonist, which share a common site, and provides a basis for the development of

22 oundaries of gains/losses tended to cluster, common sites being 54.5-55.5 Mb and 57.4-58.8 Mb.

23 by 24% (35 of 145) of patients with the most common sites being breast cancer (9 of 35; 74%) and pros

24 ection for the axial skeleton, with the most common sites being the sacrum, skull base, and spine.

25 ent natural protein scaffolds that bind at a common site between the C(H2) and C(H3) domains.

26 inal halves of the polypeptide, cluster at a common site between trimers.

27 ustly form metastases in the liver, the most common site clinically.

28 adenosine have been proposed to interact at common sites downstream of calcium entry at amphibian mo

29 irect comparison of the two editing kinds at common sites during substrate minimization and demonstra

30 This subpocket may be a common site for binding nonselective inhibitors of PDEs.

31 The liver is a common site for cancer metastases in which the entrance

32 The most common site for carcinoid metastases is the liver.

33 area around the peptide p7 position forms a common site for cation binding in metal allergies.

34 that influence pediatric bone strength at a common site for childhood fractures, we performed a sex-

35 er drainage of the pancreas remains the most common site for drainage of exocrine secretions, enteric

36 Thus, the DRG is the most common site for ectopic discharge generation after spina

37 n in inguinal white adipose tissue (iWAT), a common site for emergent active iBAT.

38 The gastrointestinal tract is the most common site for extranodal lymphomas.

39 The most common site for initiation of the thrombus appears to be

40 s in 11p15.5, a chromosomal region that is a common site for loss of heterozygosity in certain sarcom

41 The supraclavicular region is a common site for lymph node metastases.

42 The gingiva is the most common site for metastases to oral soft tissues, with st

43 n the peritoneal cavity, omental tissue is a common site for metastatic disease arising from intraper

44 PKD1 is the most common site for mutations in human autosomal dominant po

45 The small intestine is a more common site for nonsteroidal antiinflammatory drug (NSAI

46 The small intestine may be a more common site for nonsteroidal antiinflammatory drug toxic

47 21 domain of hsp90, these results indicate a common site for nucleotides and geldanamycin that regula

48 The most common site for PC mutations is the outermost arginine o

49 only serve as an intermediate but also as a common site for polarized sorting on the endocytic and s

50 structions about the knee, which is the most common site for primary bone sarcomas.

51 eath in the Western world, and the lung is a common site for recurrence of extrathoracic malignancies

52 The conjunctiva is a common site for the allergic inflammatory response due t

53 al melanoma cells toward the liver, the most common site for the formation of uveal melanoma metastas

54 Primary care is the most common site for the treatment of depression.

55 ha preferred to phosphorylate Ser-43/Ser-45 (common sites for all isozymes) and thus reduced the maxi

56 rts the view that exons 6 and 7 are the most common sites for ECM1 mutations in lipoid proteinosis.

57 stasis at the time of the diagnosis and most common sites for metastasis are lung, regional lymph nod

58 The most common sites for recurrence are the transplanted liver (

59 ts related gene (Erg) and Ets1 were the most common sites for transposon insertion in SB-induced JAK2

60 The most common sites for ulceration were the dorsal aspect of ha

61 TID bind in a mutually exclusive manner to a common site in the closed channel that is spatially sepa

62 ults suggest that URAT1 inhibitors bind to a common site in the core of the transporter and stericall

63 ly sternopleural bristle number, and another common site in the fifth intron affected only abdominal

64 shown by photoaffinity labeling to bind to a common site in the ion channel in the closed state.

65 A common site in the second intron of Delta affected only

66 caudal paravertebral directions occurs at a common site in the ventral mesenchyme, established by th

67 both distinct, nonoverlapping sites, and on common sites in a competitive fashion.

68 Vertebrae are the most common sites in adults vs femora in children.

69 a decoy for microRNAs (miRNAs) that bind to common sites in the 3' untranslated regions (UTRs).

70 The most common sites included bladder (95; 16%), laryngeal or to

71 The most common sites involved were the skeleton (90.6% of patien

72 ecific first exons, which are spliced onto a common site just upstream of the translation initiation

73 were found on GAPDH for G93A, including one common site (K114) for H46R/H48Q, which is not found on

74 terface of the nondesensitized receptor at a common site located on the twofold axis of molecular sym

75 The data indicate that cocaine binds to a common site located within the internal vestibule and in

76 We have designated this gene Clg (common-site lymphoma/leukemia guanine nucleotide exchang

77 r the hydrophobic cleft of the beta clamp, a common site occupied by proteins that bind the beta clam

78 The most common site of a small primary tumor initially thought t

79 to hypothesize that annexin 7 may serve as a common site of action for calcium, guanine nucleotide, a

80 e results of the "cutoff" analysis suggest a common site of action for the anesthetics isoflurane, ha

81 iles for the IIa cation series, indicating a common site of action.

82 Recently, BRAF has been identified as a common site of activating mutations, and, although many

83 The most common site of addition is the last A of the ATAA 3' ove

84 with tau in entorhinal cortex, which is the common site of age-related tauopathy.

85 e main renal artery bifurcation was the most common site of aneurysms (60%).

86 These results support a common site of ATP action at P2X receptors and suggest t

87 Intracranial hemorrhage (ICH) was the most common site of bleeding requiring reversal (n = 59; 70.2

88 rts of intracranial hemorrhage, and the most common site of bleeding was skin.

89 Bone is the most common site of breast cancer metastasis and once establi

90 Because bone is such a common site of breast cancer recurrence, we sought to de

91 Skin is the most common site of cancer in humans.

92 The bone is the third most common site of cancer metastasis.

93 Bone is a common site of cancer metastasis.

94 and 6.8% in CsA-treated recipients; the most common site of CMV disease was the gastrointestinal trac

95 patients with cancer, and is the third most common site of CNS metastases.

96 The nares were not the most common site of colonization.

97 ecause these and previous results indicate a common site of contact between the PH and catalytic doma

98 l cancer metastasizes to the liver, the most common site of dissemination in this cancer.

99 Bone is the most common site of distant metastases from breast carcinoma.

100 Because the liver is the most common site of distant metastasis in colorectal cancer,

101 The most common site of distant recurrence was lung (69% of all p

102 The most common site of DPC formation in DNA following treatment

103 The most common site of engraftment was the heart, apparently bec

104 e normal microflora and dietary Ags and is a common site of entry for pathogens.

105 penetration into mucosal epithelial cells, a common site of exposure to viruses.

106 The only common site of expression for all 10 known active genes

107 Because brain metastases constitute the most common site of failure in these patients, future studies

108 Brain metastasis was the most common site of failure.

109 The most common site of first recurrence after lymph node dissect

110 occurred in 55 patients (55%), and the most common site of first recurrence was within the draining

111 me 10 (RNO10) is orthologous to human 17q, a common site of genetic aberrations in breast cancer.

112 The most common site of GIT uptake was the colon, and of the 240

113 The liver is a common site of hematogenous metastasis.

114 n alter proliferation in epidermis, the most common site of human cancer.

115 The respiratory tract is the second most common site of infection for PASTEURELLA: Of the more th

116 The lung is a common site of infection in patients with cancer.

117 The gastrointestinal tract is a common site of infection in the opportunistic host.

118 In extrapulmonary tuberculosis, the most common site of infection is within the lymphatic system,

119 The most common site of infection was pulmonary (31%).

120 The most common site of infection was skin, followed by pneumonia

121 tive MSM, with the anal canal being the most common site of infection.

122 lateral addition of TPeA(+) ions confirmed a common site of interaction within the pore that possesse

123 cation and alkaloid compete for access to a common site of interaction.

124 to CBP, suggesting that the homeodomain is a common site of interaction.

125 somers of flupentixol are mediated through a common site of interaction.

126 The superior limbus was the most common site of involvement (95%).

127 transplants (HCTs), and the skin is the most common site of involvement.

128 The most common site of major bleeding was gastrointestinal, occu

129 The liver is a common site of metastases from cancers from most sites,

130 The skeleton is a common site of metastases in lung cancer, an event assoc

131 The most common site of metastasis for breast cancer is bone.

132 The lung is a common site of metastatic and primary tumor growth, and

133 anced disease, with the liver being the most common site of metastatic disease.

134 soft tissue sarcoma, the lungs are the most common site of metastatic disease.

135 The single most common site of missed adenoma glands was in the tracheal

136 equivalent to murine 172) is the second most common site of missense mutations in p53 in human breast

137 The most common site of MRI abnormalities was the right ventricul

138 Shoulder joint is a common site of musculoskeletal pain caused, among other

139 gression in the medial compartment, the most common site of OA involvement at the knee.

140 The ureteroneocystostomy (UNC) was the most common site of obstructions (22 of 41), leaks (four of f

141 The most common site of occurrence in neonates is in the sacrococ

142 ral data suggested the microvasculature as a common site of origin for these cells, we analyzed micro

143 The lung was the most common site of positive cultures.

144 stance inevitably develops, with the brain a common site of progression.

145 cus) is anatomically separated from the most common site of reactivation disease (the apex).

146 The most common site of recurrence was the brain.

147 ntral nervous system metastasis was the most common site of relapse and death.

148 amma (PI3Kgamma), was recently reported as a common site of retroviral insertion in T-cell lymphomas

149 Here we show that Evi24, a common site of retroviral integration in AKXD B cell and

150 Evi27 is a common site of retroviral integration in BXH2 murine mye

151 I27 was identified through its location at a common site of retroviral integration in BXH2 murine mye

152 Evi5 is a common site of retroviral integration in T-cell lymphoma

153 Here we present the analysis of a common site of retroviral integration on mouse chromosom

154 The preauricular region was the most common site of SLN.

155 m of the Myb gene and appears to be the most common site of somatic viral integration in BXH-2 mice.

156 e (nodes and/or viscera), bone disease (most common site of spread), and symptoms.

157 The optic nerve is a common site of tissue damage in multiple sclerosis (MS)

158 Liver is a common site of tumor spread and in approximately 30% of

159 Mediastinal lymph nodes are the most common site of tumor spread in non-small cell lung cance

160 thin the homeodomain and was identified as a common site of viral integration in myeloid leukemias ar

161 eobox gene that was originally isolated as a common site of viral integration in myeloid tumors of th

162 he conformational L1 epitope with Asp35 is a common site of vulnerability for potent neutralization b

163 The most common sites of abnormalities on the delayed scans were

164 suggest nicotinic acetylcholine receptors as common sites of action for nicotine and alcohol.

165 se regions of copy number decreases are also common sites of allelic loss, further implicating these

166 nal, and intracranial arteries were the most common sites of aneurysm; dissection most often occurred

167 Although the most common sites of atrial ectopy that trigger atrial fibril

168 Common sites of breast cancer metastasis include the lun

169 s that mesenchymal fibroblasts isolated from common sites of breast cancer metastasis provide a more

170 Liver is one of the most common sites of cancer metastasis.

171 steolytic bone lesions and liver metastases, common sites of clinical metastases.

172 The most common sites of contamination were sink drains, faucets,

173 s revealed regional losses identifying three common sites of deletions at 5p15.1-15.2, 5q11, and 5q34

174 Most common sites of disease were gastrointestinal tract (n=2

175 The most common sites of EPTB were lymphatic (28%), disseminated

176 Common sites of expression for both kinds of constructs

177 abdominal lymph nodes, and bone are the most common sites of extrahepatic metastatic HCC.

178 robe the energetic coupling, if any, between common sites of fluorination in both the azaindole and p

179 he jejunum and ascending colon were the most common sites of gastrointestinal wall thickening; each w

180 s of 46 and 53 years, respectively; the most common sites of infection in the two groups were skin/so

181 The most common sites of infection were respiratory tract (53%) a

182 ) cells), non-recirculating cells located at common sites of infection, can achieve near-sterilizing

183 The jejunum and ascending colon are the most common sites of involvement.

184 p, and 22q) have previously been shown to be common sites of karyotypic and allelic loss in MM, our c

185 The most common sites of LOH were on 17p, 17q, 16q, 11q, and 14q,

186 nd supraclavicular nodes (41%) were the most common sites of LRR.

187 The common sites of metastases are the periaortic lymph node

188 binding, and interestingly, one of the most common sites of mutation in all three kinases is a highl

189 Common sites of noncompaction were the apical (100%), mi

190 of mitochondria and is also one of the most common sites of oncocytic tumours, has been limited to d

191 The most common sites of origin of infection were the perineum (F

192 ent memory CD8(+) T (TRM) cells are found at common sites of pathogen exposure, where they elicit rap

193 The most common sites of primary colon cancer were sigmoid/rectum

194 We identified 88 candidate cancer genes near common sites of proviral insertion.

195 method to monitor micrometastatic disease in common sites of recurrence.

196 lizing these retroviral integration sites to common sites of retroviral integration (CISs).

197 o altered in the lung and bladder, which are common sites of secondary infection in burn-injured pati

198 were relatively isolated; however, the most common sites of star formation are clusters.

199 In addition to predicting common sites of UGT conjugation, like hydroxyl groups, i

200 s can thus be identified by viral tagging as common sites of viral integration in BXH2 leukemias.

201 at low Ca2+ competes with tropomyosin for a common site on actin and drives tropomyosin movement to

202 unophilins CyP-40 and FKBP52/hsp56 bind to a common site on hsp90 and that they exist in separate het

203 The use of a common site on lambda Int for both homotypic and heterot

204 group of small molecules that all bind to a common site on Ras.

205 yridine receptor and are thought to act at a common site on ryanodine receptor type 1 (RyR1) importan

206 s condition, filtered light chains bind to a common site on Tamm-Horsfall protein (THP), which is pro

207 We show that a common site on TBP is used for transcription initiation

208 rmined by X-ray crystallography to bind to a common site on the cellular chaperone heat shock protein

209 These results imply that there is a common site on the RecA protein filament for secondary D

210 eria are structurally diverse, they target a common site on the receptor.

211 that activators and inhibitors interact at a common site on the receptor.

212 increased binding of both PLTP and apoA-I to common sites on the cell surface.

213 ol strikingly integrated primarily into four common sites out of 3.1 x 10(9) possible human genome lo

214 ts, all having arginine substitutions at two common sites (positions 402 or 401 and position 418), we

215 t CgA strains acquired their resistance at a common site prior to their spread to the college communi

216 iation for CVD mortality, no association for common site-specific cancers and a possible positive ass

217 found no clear harm or benefit for total or common site-specific cancers.

218 vestigate the links between BMI and the most common site-specific cancers.

219 tegration of wild-type AAV have identified a common site-specific integration locus on human chromoso

220 ed for MORF protein combinations affecting a common site, suggesting their functional relevance.

221 The most common sites tested were abdominal fluid (dogs and cats)

222 , occurs in follicular lymphomas (FL) at two common sites: the major breakpoint region (MBR) and the

223 n to methylate 23S ribosomal RNA (rRNA) at a common site, thereby rendering the ribosomes MLS resista

224 Although the kidney is the most common site, they can occur anywhere in the body.

225 receptor agonists and antagonists bind to a common site, they produce different conformational chang

226 '-nucleotide PDE/ATP pyrophosphatase, with a common site (Thr210) for the formation of covalently bou

227 g (ChIP-seq), which detects PRC1 proteins at common sites throughout the genome, we did not find evid

228 w Ca(2+) and competes with tropomyosin for a common site to drive tropomyosin to the B-state location

229 Bone is the most common site to which breast cancer metastasizes.

230 enthalpy change of the Cd(2+) binding to the common site was found to be related linearly to the ioni

231 ) form dimeric coiled-coils and bind IC at a common site, we observe distinct binding modes for each

232 ough dependent on patient location, the most common sites were abdomen, lung, and wound; the most com

233 ansferases p300 and Gcn5/Trrap, and occupies common sites with Gcn5 within the human globin loci.

234 in clinical development act by binding to a common site within Smoothened, a critical pathway compon

235 pram inhibit TASK-3 function by binding at a common site within the channel intracellular pore region

236 derivative chromosomes that have joined to a common site within the low copy repeat B (LCR-B) region

237 Pase P-loop of MinD compete for binding to a common site within the MinD structure, thereby providing