ライフサイエンスコーパス: compaction

1 roteins, therefore mediating heterochromatin compaction.

2 nts, adhesive forces, membrane curvature and compaction.

3 op-capture mechanism for initial binding and compaction.

4 re more stable loops and dramatic chromosome compaction.

5 chromatid disentanglement during chromosome compaction.

6 lve morphogenesis and ventricular trabeculae compaction.

7 s through histone modification and chromatin compaction.

8 erization and contributes to sperm chromatin compaction.

9 o capture the observed nonmonotonic trend in compaction.

10 ints for axis attachment and thus chromosome compaction.

11 hibit defects in PC1 expression and collagen compaction.

12 hts into the machinery underlying chromosome compaction.

13 ransfer RNA selection to drive messenger RNA compaction.

14 ss involving chromosome expansion as well as compaction.

15 nker histone (LH) is essential for chromatin compaction.

16 mechanism by which SUMO-3 inhibits chromatin compaction.

17 hemselves have evolved to regulate chromatin compaction.

18 eyond their basal functionality in chromatin compaction.

19 riptional activation but is important in DNA compaction.

20 dent of spatial scale for systems under weak compaction.

21 ns while most chromatin mass undergoes hyper-compaction.

22 e interplay between genome accessibility and compaction.

23 eboidal morphology and limits collagen I gel compaction.

24 anscriptional programs and exhibit chromatin compaction.

25 er to enrich H4K20me1 and trigger chromosome compaction.

26 into how citrullination regulates chromatin compaction.

27 ter fusion, germ cell ensheathment and gonad compaction.

28 h have evolved several mechanisms for genome compaction.

29 DNAs, promoting stem formation and chromatin compaction.

30 to align collagen gels using guided cellular compaction.

31 hat only the multimer shows ATP-enhanced DNA-compaction.

32 r traction, intercellular tension and tissue compaction.

33 expression feeds back on itself via nucleoid compaction.

34 How is this compaction accomplished?

35 settling, which induces physical stress and compaction, aggregates blood cells, and causes collatera

36 However, compaction alone does not account for the formation of d

37 This barrier modulates the degree of plaque compaction, amyloid fibril surface area, and insulation

38 is associated with a process of whole-embryo compaction analogous to that observed in mammals [4-7].

39 Mutant neurons exhibit increased chromatin compaction and a striking redistribution of the H4K20me3

40 toward a better understanding of how genome compaction and access are regulated within the cell.

41 chromatin structure of DNA determines genome compaction and activity in the nucleus.

42 uctuation spectroscopy (FFS) to evaluate the compaction and aggregation of tetra-nucleosomes containi

43 at this protein helps coordinating chromatin compaction and axial contraction to properly shape mitot

44 n 1/keratin 10 end domains to allow filament compaction and bundling, whilst also retaining extensibi

45 lls revealed aberrant and reduced nucleosome compaction and chromatin association of the key replicat

46 Patients with left ventricular non-compaction and congenital heart disease often need surgi

47 assessed by IM, with EGCG leading to protein compaction and DA to its extension.

48 Depletion forces play a role in the compaction and decompaction of chromosomal material in s

49 a reproducible hysteresis in the process of compaction and decompaction of the Dps-DNA complex.

50 Under compaction and dewatering, the size and geometry of such

51 e of chromosome stress, created by chromatin compaction and expansion.

52 state plays critical roles that involve both compaction and expansion.

53 Experimental compaction and finite element analysis were utilized to

54 It has been implicated in chromatin compaction and gene regulation and is anticipated to pla

55 deacetylase inhibitors can relieve chromatin compaction and gene repression, without altering H3K27me

56 sive complexes 1 and 2) leading to chromatin compaction and gene silencing.

57 3), a modification associated with chromatin compaction and gene silencing.

58 thylation has been associated with chromatin compaction and gene silencing.

59 d structuring) protein affects both nucleoid compaction and global gene regulation.

60 nd has been linked to higher-order chromatin compaction and global gene silencing.

61 ases considerably over time during aggregate compaction and growth.

62 end at various lengths to achieve structural compaction and high packing densities.

63 We show that morula compaction and ICM formation depend on PC7 and the relat

64 omosome features and recapitulate chromosome compaction and individualization during mitotic condensa

65 amyloid fibrils and plaques promoting their compaction and insulation.

66 ive microglia barrier that regulates amyloid compaction and insulation.

67 tin organisation, disrupting heterochromatin compaction and long-range genomic interactions.

68 eficiency leads to defective sperm chromatin compaction and male infertility in mice, mirroring the o

69 ionary mechanism for regulation of chromatin compaction and may explain the frequent mutations of the

70 tightly correlated to the state of chromatin compaction and not to the levels of H3K27me3-its removal

71 nuclear localization, chromatin positioning/compaction and overall organ function.

72 SUMOylation, Mer2 mediates global chromosome compaction and post-recombination chiasma development.

73 g transcription factor ZEB1 stimulated Golgi compaction and relieved microRNA-mediated repression of

74 R that pulls actin bundles, resulting in the compaction and removal of the cell body.

75 in other condensin complexes to control the compaction and resolution of all mitotic and meiotic chr

76 nd sequential steps during TRF2-mediated DNA compaction and result in folded DNA structures with prot

77 w this activity specifically promotes proper compaction and segregation of chromosomes during mitosis

78 allow NRL variations to regulate both fiber compaction and selective DNA exposure.

79 of nucleosome arrays to undergo salt-induced compaction and self-association.

80 Experimentally, the level of compaction and shape is often determined either by small

81 romosomes yields a model in which the global compaction and shape of large-Mbp chromatin domains rema

82 lexible polyimide substrate followed by cold compaction and sintering.

83 entrapping chromosomes to promote chromosome compaction and sister-chromatid cohesion.

84 resents as two conformers undergoing similar compaction and structural rearrangements, prior to therm

85 Our findings imply that compaction and subsequent repression of large chromatin

86 lates telomere structures by promoting dsDNA compaction and T-loop formation.

87 nteraction with wild-type cells causes their compaction and that crowding is sufficient for scrib(KD)

88 er histone H1 are involved in both chromatin compaction and the regulation of mitotic progression.

89 Deletion of Nanog leads to chromatin compaction and the remodeling of heterochromatin domains

90 Upon mechanical compaction and thermal annealing, GPs can achieve a ther

91 was associated with key regulators of Golgi compaction and vesicle transport in pull-down assays and

92 estigating the quasi-static avalanche angle, compaction, and dilatancy effects in different nonbuoyan

93 rget selection to axon wrapping and membrane compaction, and discuss how understanding these processe

94 linked gene expression, reduces X chromosome compaction, and disrupts X chromosome conformation by di

95 e associated with CpG methylation, chromatin compaction, and histone modifications that effectively s

96 f the keratin macrofibrils, their continuous compaction, and increasingly parallel orientation.

97 wth form the basis of both trabeculation and compaction, and mouse models indicate that cardiomyocyte

98 oduce the average loop length, the degree of compaction, and the general loop-array morphology of com

99 e of histone tails, their roles in chromatin compaction, and the impact of lysine acetylation, a wide

100 e interactions are instrumental in chromatin compaction, and understanding NCP self-assembly is impor

101 loops are highly dynamic but provide little compaction; and a dense state, where there are more stab

102 fe-threatening risks of left ventricular non-compaction are ventricular arrhythmias or complete atrio

103 We infer that hydrolysis leads to a compaction around the E-site nucleotide at longitudinal

104 oop destabilization both result in chromatin compaction around the VIM promoter and a reduction in th

105 Thereafter, rather than smooth, progressive compaction as generally envisioned, progression to metap

106 ro and in vivo by promoting mesenchymal cell compaction as seen in each pore of the scaffold.

107 t with its function in mRNP organization and compaction as well as poly(A) tail length regulation.

108 tubules do not show the longitudinal lattice compaction associated with EB protein binding and GTP hy

109 hat heterochromatin mediates chromatin fibre compaction at centromeres and promotes prominent inter-a

110 pression of multiple genes through chromatin compaction at its target genes.

111 ge induces a transient decrease in chromatin compaction at the damage site and an increase in compact

112 Yeast MTs were not observed to undergo compaction at the interdimer interface as seen for mamma

113 ed to rationalize the significantly improved compaction behavior of the monoclinic form of paracetamo

114 actionations were acquired before burial and compaction, but also show evidence of postdepositional a

115 crucial roles in chromosome organization and compaction, but the mechanistic basis for its functions

116 of a small-genome organism increased linear compaction by as much as 40%, while their absence marked

117 s measurements to resolve the process of DNA compaction by Dps.

118 studies, we also propose a novel mode of DNA compaction by H-NS termed intrabridging to explain over

119 rtantly, these findings imply that chromatin compaction by nucleosome stacking protects nucleosomal D

120 TFAM dimerization enhances mitochondrial DNA compaction by promoting looping of the DNA.

121 rized condensin in driving gradual chromatin compaction by step-like and slow "creeping" dynamics con

122 study demonstrates that efficient chromosome compaction can be achieved solely by an active loop-extr

123 us forms of congenital heart disease and non-compaction cardiomyopathies, it remains unclear how embr

124 in these precursors leads to ventricular non-compaction cardiomyopathy, a poorly understood condition

125 reveal novel insights into IHF-mediated DNA compaction depending on the placement of its preferred b

126 equired for gene silencing, while chromosome compaction does not appear to be an important H-NS funct

127 a new 3D-PALM method, revealing substantial compaction during anaphase.

128 They reach their greatest compaction during chromosome condensation in mitosis.

129 o propose a model for its role in chromosome compaction during meiosis.

130 as surprisingly insufficient to drive matrix compaction during valve maturation.

131 The data implicate a compaction effect in the methyl transfer step that is co

132 ng that the global conformational search and compaction electrostatics are energetically independent

133 hree distinct ways: delaying alpha-subdomain compaction, facilitating beta-strand intercalation, and

134 neonatal endocardial cells during trabecular compaction generates a distinct compartment of the coron

135 thyl esters were prepared utilizing a direct compaction grade powder with beta-cyclodextrin as encaps

136 The key process steps such as powder compaction, graphite burnout during partial sintering, m

137 sible for DNA expression, recombination, and compaction has been difficult to visualize as functional

138 Compaction has recently become the bottleneck in assembl

139 everal genes that cause left ventricular non-compaction have been identified.

140 Whereas defects in chromatin compaction have no observable effect on axial contractio

141 Fe1.6O4, prepared by magnetic field assisted compaction, have been reported in this study.

142 ous increases in chromatin accessibility and compaction heterogeneity.

143 Given the involvement of p53, compaction hypersensitivity may be widespread among dama

144 motes chromatin stability by DNA bending and compaction imposed by its lysine-rich domain and that it

145 ve maturation in vitro, PN promoted collagen compaction in a kinase-dependent fashion.

146 stic deformation was observed to precede the compaction in a stochastic, random structure.

147 low-energy grain boundaries by liquid-phase compaction in Bi(0.5)Sb(1.5)Te3 (bismuth antimony tellur

148 40%, while their absence markedly diminished compaction in cells with large genomes.

149 arkness resulted in more increased chromatin compaction in euchromatin and decompaction in heterochro

150 used to investigate variations in chromatin compaction in fixed human chromosomes.

151 , necessitating greater degrees of chromatin compaction in higher eukaryotes, which have evolved seve

152 1) histones play critical roles in chromatin compaction in higher eukaryotes.

153 erphase nuclei showed variation in chromatin compaction in interphase and the formation of chromosome

154 r of CCS approximately 1200 A(2), undergoing compaction in line with the reported Tmelt = 360.15 K be

155 ssays and was required to reconstitute Golgi compaction in PAQR11-deficient tumor cells.

156 Finally, we show that chromatin compaction in preimplantation embryos can partially proc

157 This compaction in quiescence requires the condensin complex.

158 mal spacing of chromatin and reduced nuclear compaction in syncytial embryos.

159 om 7.5 to 1 M, thereby suggesting pronounced compaction in the protein dimensions in the burst phase.

160 Rac1 pathway was necessary to induce matrix compaction in vitro through increased cell adhesion, elo

161 vation does not affect short-range chromatin compaction, inactivation of both pathways causes synergi

162 icantly to the overall free energy change of compaction, interactions mediated by the uncharged resid

163 underlying the active process of chromosome compaction into a stack of loops is unknown.

164 s preferred binding sites; mIHF promotes DNA compaction into nucleoid-like or higher order filamentou

165 chemical environments and that binding site compaction is a determinant of both resting and active a

166 We propose that CBX2-driven nucleosome compaction is a key mechanism by which PcG proteins main

167 Compaction is an important data reduction step in most d

168 This compaction is coupled to a stabilization of the cytosoli

169 We find that the extent of crowding-induced compaction is dependent not only on crowder size and con

170 In bacteria, this compaction is governed by the family of nucleoid-associa

171 ly reduced, although no change in chromosome compaction is observed.

172 They also suffer the compaction issue that reduces permeate flux in pressure-

173 on of ring components and to constrain their compaction kinetics.

174 ured from SAXS experiments, which suggest no compaction, leading to a disagreement with the FRET expe

175 en found in patients with left ventricle non-compaction (LVNC), we investigated members of our family

176 Magnetic field assisted compaction (MC) has been employed to process Zr-doped co

177 In particular, we measured DNA compaction mediated by BsSpo0J using a recently develope

178 Lack of compaction might reflect slower GTP hydrolysis or a diff

179 yos at the blastomere, polyploid blastomere, compaction, morula and blastocyst-like stages by light,

180 of the folding process indicated that double-compaction occurred and that the formed single-chain par

181 is observed, and is associated with complex compaction occurring close to the reported solution T(m)

182 cetylation of histone H4 promote short-range compaction of chromatin during early anaphase.

183 phase nuclei, the 100- to >1,000-fold linear compaction of chromatin is difficult to reconcile with i

184 in passive pulling into micropipettes, local compaction of chromatin is observed coincident with depl

185 in the nuclear periphery accompanied by the compaction of chromatin.

186 In the model, the reported compaction of chromosomal DNA caused by SYCP3 would resu

187 ing of proliferation-promoting genes through compaction of chromosomes into senescence-associated het

188 Compaction of chromosomes is essential for accurate segr

189 sent an algorithm and a tool bcalm 2 for the compaction of de Bruijn graphs.

190 that mitigates hydraulic compression on the compaction of dense-selective layer and sublayer and hel

191 The compaction of diffuse interphase chromatin into stable m

192 single-DNA magnetic tweezers assay to study compaction of DNA by yeast condensin, with the result th

193 ied and phosphorylated HP1alpha induce rapid compaction of DNA strands into puncta, although with dif

194 This process is remarkable considering that compaction of DNA to near-crystalline densities within t

195 formed in open sea by random aggregation and compaction of fibers held together by friction forces.

196 o remodel the extracellular matrix, inducing compaction of fibrin into bundled agglomerates tightly a

197 rimary force maintaining the greater genomic compaction of flying birds and bats relative to their fl

198 ein-DNA complexes in eukaryotes that provide compaction of genomic DNA and are implicated in regulati

199 th poly(A) tail length regulation and in the compaction of mature transcripts to facilitate nuclear e

200 The proposed approach employs the compaction of metal-oxide sub-micron powders with a grap

201 The compaction of model copolymers containing only one cross

202 , folding occurred discretely via sequential compaction of N-terminal, alpha-helical, and alpha/beta-

203 ng in restricted radial diffusion due to the compaction of neuronal fibres.

204 The compaction of nucleosomal structures creates a barrier f

205 Compaction of other, commercially available, omega-3 pow

206 We report the intramolecular double compaction of sequence-controlled linear macromolecules

207 ncentrations, are monomers that induce tight compaction of single-stranded RNA.

208 ap, thereby permitting assessment of the DNA compaction of such regions in a live cell.

209 erin and demonstrate that shelterin-mediated compaction of telomeric chromatin provides robust protec

210 Adding linker histone H1 further increased compaction of the A-tract arrays while maintaining struc

211 rmal denaturation experiments delineates the compaction of the alpha-fold by an electrostatic compens

212 we use our approach to validate the further compaction of the already unfolded state of phosphoglyce

213 he averaged structures demonstrates a marked compaction of the basal body (4 nm) occurs when the need

214 intrinsic viscosities suggest some degree of compaction of the carbohydrate chains around the protein

215 ng a fluorescence-based assay to study local compaction of the chromatin fiber in living yeast cells,

216 We find that the compaction of the denatured state is related to changing

217 The compaction of the ENC domain was found significantly hig

218 atterning techniques to show that mechanical compaction of the extracellular matrix during mesenchyma

219 show that proton application causes a global compaction of the extracellular subunit interface, coupl

220 ry, we show that both inhibitors promote the compaction of the initially formed beta2m dimer, which c

221 n of the structure was observed ahead of the compaction of the lattice, while no elastic deformation

222 disorder results from intrauterine arrest of compaction of the loose interwoven meshwork of the fetal

223 up (HMG) protein involved in maintenance and compaction of the mitochondrial genome into nucleoids.

224 tosis activates the complex for a dual role: compaction of the mitotic chromatin and regulation of po

225 either a ligand induced dimerization and/or compaction of the monomer are considered.

226 DNA and proteins required for the efficient compaction of the nearly 2-meter-long human genome into

227 e cell poles and boundaries with concomitant compaction of the nucleoid.

228 SAXS studies further show compaction of the protein upon complex formation.

229 Despite the extreme compaction of the tetraodon genome and the dramatic loss

230 tribution as originating from a shift in the compaction of the two different families of conformation

231 Our results demonstrate that compaction of the type IIbeta holoenzyme does not requir

232 regions shows no major change in the overall compaction of these chromosome regions during their DNA

233 oter, with the insertion of a nucleosome and compaction of this region.

234 ific literatures and patents, related to the compaction of TMUPS.

235 nuclei consistent with variable longitudinal compaction of two-start helical fibres.

236 acromolecular crowding are expected to cause compaction of unfolded and disordered proteins, the exte

237 Re-compaction of Von Willebrand factor is accelerated by in

238 in cryo-electron microscopy, Bim1 causes the compaction of yeast microtubules and induces their rapid

239 ations to track the effect of impact-induced compaction on these materials.

240 conformers, which undergo slight structural compaction or annealing before dissociation.

241 rol gene accessibility by altering chromatin compaction or nucleosome positioning.

242 changes in the global large-scale chromatin compaction or shape of these large-scale chromatin fiber

243 Increased soil strength due to soil compaction or soil drying is a major limitation to root

244 Here we show that, when this normal compaction pathway is defective, the histone acetyltrans

245 king the results together, we identify a new compaction pathway of mammalian pericentric heterochroma

246 lish that the histone-based mechanism of DNA compaction predates the nucleosome, illuminating the ori

247 of the compact is not only determined by the compaction pressure but also significantly influenced by

248 The compaction procedure is adaptive to additive manufacturi

249 restriction role of ER-PM contacts over ring compaction process for proper actomyosin ring assembly i

250 e that EMT initiates a PAQR11-mediated Golgi compaction process that drives metastasis.

251 ulk of the ventricular wall derives from the compaction process, yet the arrest of this process can s

252 cell-autonomous mechanisms contribute to the compaction process.

253 itral valve formation and alterations in the compaction process.

254 DNA interactions and pre-existing chromatin compaction promote binding.

255 The compaction reaction involves step-like events of 200 nm

256 The compaction reactions are largely insensitive to DNA tors

257 Here, we demonstrate that a functional compaction region is necessary for proper body patternin

258 comb repressive complex 1 (PRC1), contains a compaction region that has the biochemically defined act

259 , but the contributions of altered chromatin compaction remain unclear.

260 ethylation directly contributes to chromatin compaction remains an open question.

261 f the mechanism underlying TRF2-mediated DNA compaction requires additional information regarding DNA

262 ents with high debris usually possess strong compaction resistance to preserve original pores.

263 ese and associated factors lead to chromatin compaction, resulting in steric exclusion of regulatory

264 nd management and land degradation (erosion, compaction, sealing and salinization).

265 ould be modulated by modifying the chromatin compaction state and remodeling processes.

266 rotein-DNA structure interact leading to DNA compaction, suggesting a mechanism for axial filament fo

267 ccessful probing of differences in chromatin compaction suggests that FLIM has enormous potential for

268 tion, synovial joint formation and interzone compaction, tendon maturation as monitored by ScxGFP, an

269 sult contradicts inferences regarding global compaction that are derived from heuristics based on ami

270 nctions in this process to control both mRNP compaction that facilitates movement through nuclear por

271 CTCF mediates one level of compaction that folds the locus into several 250- to 400

272 hat contributes to increased chromatin fiber compaction that is propagated under physiological condit

273 ed activation prevents the gradual chromatin compaction that occurs naturally in developmental progre

274 are discussed in the context of active site compaction that requires an ionization of substrate with

275 e scribble (scrib(KD)) are hypersensitive to compaction, that interaction with wild-type cells causes

276 he most extended chains experience up to 24% compaction, the most compact chains show virtually no ch

277 Left ventricular non-compaction, the most recently classified form of cardiom

278 polypeptide chain in bulk and the degree of compaction: the most extended chains experience up to 24

279 action at the damage site and an increase in compaction to adjacent regions, which together facilitat

280 ping mechanisms, including intra-chromosomal compaction, topoisomerase action and Holliday junction r

281 ution, we temporally resolve single-molecule compaction trajectories of DNA polymers, guided by the c

282 tone H4 (H4K20) has been linked to chromatin compaction, transcription, DNA repair and DNA replicatio

283 e interface that play a dominant role in the compaction transition and also reveal salt bridging, van

284 interactions and residues involved in such a compaction transition of gp17.

285 ributed to defective segregation or nucleoid compaction, two-ended breaks are expected.

286 Compaction, via activation of Rho-associated kinase (ROC

287 elastic response of the material, while the compaction was consistent with a model for compression o

288 not completely maintain tension when matrix compaction was resisted by boundaries, which manifested

289 with drugs that disrupt or promote chromatin compaction, we find that HP1-alpha dimers spatially redi

290 domain of mammalian histone H1 in chromatin compaction, we speculate that HMO1 promotes chromatin st

291 HP1 had only mild effects on heterochromatin compaction, whereas dim-3 caused more drastic changes, s

292 ypermethylated dsDNA, pointing at structural compaction which may facilitate DNA packaging in vivo.

293 tive plaque encapsulation and reduced plaque compaction, which is associated with worsened axonal pat

294 , TRF2, and TIN2 mediate telomeric chromatin compaction, which was proposed to minimize access of DDR

295 lthough, in the case of left ventricular non-compaction with congenital heart disease, disturbance of

296 Instead, they support a continuous global compaction with increasing polyQ length that derives fro

297 measures millisecond variations in chromatin compaction with submicron resolution.

298 keg, a mix of partial excavation and gradual compaction with the strategic placement of filling mater

299 construction of soft nano-objects via chain compaction, with an emphasis in dynamic, letter-shaped a

300 leases nuclear expansion and heterochromatin compaction within conspicuous chromocenters.