ライフサイエンスコーパス: compartment

1 ompany the viral genome beyond the endosomal compartment.

2 memory B cells that replenish the IgE(+) PC compartment.

3 d composition of this innate-like lymphocyte compartment.

4 l capacity of the proliferating keratinocyte compartment.

5 ng a novel role for TREM2 in the non-myeloid compartment.

6 by subsequent lipidation in the ER and Golgi compartment.

7 iquely found within the JAM-C-expressing LSC compartment.

8 either degradation or an undefined recycling compartment.

9 e presence of RE-containing LDs in an acidic compartment.

10 ynapses to MB output neurons (MBONs) in each compartment.

11 ss extension so as to insulate each neuropil compartment.

12 ivation-induced Rab7(+) endosomal/phagosomal compartment.

13 ng a more complete restoration of the T cell compartment.

14 butes to their enrichment within the hepatic compartment.

15 ollicular mature versus marginal zone B cell compartment.

16 reserve-like ISC population within the Lgr5+ compartment.

17 the endoplasmic reticulum-Golgi intermediate compartment.

18 rather than specific targeting to a singular compartment.

19 tion of other Crumbs proteins in the ciliary compartment.

20 o we investigated the role of the osteoclast compartment.

21 n gradient to adjacent cells of the anterior compartment.

22 form sheets of cells with separate cellular compartments.

23 or mapping the transcriptomes of subcellular compartments.

24 tion-interact with RNA in different cellular compartments.

25 ns are organized into phase-separated liquid compartments.

26 NFSim engines were each modified to support compartments.

27 sequences were shown to be identical in both compartments.

28 tructed for the adjacent luminal and mucosal compartments.

29 les, which vary markedly in different lesion compartments.

30 the early endosome to the late endolysosomal compartments.

31 the extent of disease involving its various compartments.

32 "glycan remodelling" process, even at distal compartments.

33 of intestinal cell populations in particular compartments.

34 n the plasma membrane and organelle membrane compartments.

35 fect of organizing the membrane into dynamic compartments.

36 myomaker trafficking between these cellular compartments.

37 at is spatially organized into different gut compartments.

38 el consisting of seventeen perfusion-limited compartments.

39 ionary behavior in a multitude of anatomical compartments.

40 eptors or entering into acidic intracellular compartments.

41 sequestration of labile Fe(2+) into vacuolar compartments.

42 ing transport between the different cellular compartments.

43 s and cellular constrictions between spindle compartments.

44 in the odontoblast-like cells and the tooth compartments.

45 ectopic stimulation, especially in neuronal compartments.

46 n and is present in nuclear and extranuclear compartments.

47 in retrograde transport between early Golgi compartments.

48 flux contribute to the maintenance of memory compartments.

49 ng whether proteins are enriched within cell compartments.

50 the study of the functions of these striatal compartments.

51 sation of protein thiols across all cellular compartments.

52 ER (distance </=30 nm) in different neuronal compartments.

53 proteins are localised to disparate cellular compartments.

54 om receptors localized exclusively at Rab4/5 compartments.

55 coherence of MU discharge between different compartments.

56 bor significantly altered T cell and NK cell compartments.

57 and VL sequences within the naive and memory compartments.

58 effects of AES on innate and adaptive immune compartments.

59 lar uptake, and distribution across cellular compartments.

60 d confirmed entry into all 4 lower extremity compartments.

61 s, protease-resistant, antibody-inaccessible compartments.

62 the central nervous system, to the different compartments.

63 thin tumor cells located in different tissue compartments.

64 expansion of natural killer (NK) and T cell compartments.

65 an intensive transformation of CBZ in these compartments.

66 und that, globally, chromatin structures and compartments A/B are highly similar at both developmenta

67 across three different lesion-related tissue compartments: (a) non-neural lesion core, (b) astrocyte

68 Late endocytic compartments accumulate around Plasmodium berghei liver-

69 xenon gas to the extravascular brain tissue compartment across the intact blood-brain barrier.

70 For instance, the two adult lung epithelial compartments (airways and alveoli) are separately mainta

71 cal production of ATP within the replication compartment allow the virus replication machinery an acc

72 ar access to smooth muscle basement membrane compartments also exhibited size-dependence.

73 ymbiotic associations between a plant's root compartment and fungi.

74 ation of oncogenic pathways in the stem cell compartment and how wild-type cells limit the proliferat

75 s a targetable pathway to curtail the M-MDSC compartment and improve bladder cancer treatment.

76 ulted in a significantly reduced thymic Treg compartment and increased susceptibility to mononuclear

77 -) hematopoietic stem/progenitor cell (HSPC) compartment and interrogated dominant clones for MDS-ini

78 tein pairs co-localized in the same cellular compartment and involved in the same biological process.

79 tease 3 (ASP3) resides in the endosomal-like compartment and is crucially associated to rhoptry disch

80 at obesity alters the composition of the HSC compartment and its activity in response to hematopoieti

81 ng dopaminergic neurons innervating the same compartment and re-engages positively reinforcing dopami

82 t baseline persisted in the liver or another compartment and reemerged in the blood 24 weeks after tr

83 gradient migrated transiently to the warmest compartment and survived as a consequence.

84 ive specificities into the follicular mature compartment and thereby likely increasing the risk for s

85 way for H. pylori to access the basolateral compartment and trigger pathogenesis.

86 V) acquires its membrane in an intracellular compartment and we show that Stx3-5R strongly reduces th

87 ZNF804A protein localized to somatodendritic compartments and colocalized with the putative synaptic

88 ery rare data on OCPs in the vast deep-water compartments and combined with surface water distributio

89 GAP/GEFs localized within multiple neuronal compartments and determine an additional 110 interaction

90 lymorphs can be formed in different cellular compartments and potentially result in distinct phenotyp

91 e positions of gene loci, find large genomic compartments and smaller topologically-associating domai

92 her levels of chromatin structures including compartments and topologically associating domains (TADs

93 y in plastids, 68 in at least one additional compartment, and 520 outside the plastid), 122 proteins

94 e-expression changes in the proximal stromal compartment, and estrogen treatment uniquely affected ge

95 t, Glut4 cannot reach the insulin-responsive compartment, and insulin-stimulated glucose uptake in ad

96 P activity in TB differs by HIV-1 status and compartment, and releases matrix degradation products.

97 ces were almost fully soluble in the gastric compartment, and then became insoluble in the intestinal

98 Biological membranes create compartments, and are usually formed by lipid bilayers.

99 mina, their dynamic links with other nuclear compartments, and their proposed roles in gene regulatio

100 ng an in situ preparation method, individual compartments are generated from small plugs of polymer s

101 Nanoscale compartments are one of the foundational elements of liv

102 e are only beginning to understand how these compartments are structurally registered and functionall

103 eclines were compared, suggesting that these compartments are tightly associated.

104 In prokaryotes, protein-based compartments are used to sequester harmful reactions and

105 effector memory responses, positioning this compartment as a potential major contributor to immunolo

106 ane export in the post-endoplasmic reticulum compartment as molecular basis for blinatumomab resistan

107 but transiently to the MHC class II loading compartment, as does Ag conjugated to H4B4.

108 that the formation of the viral replication compartment at late infection resulted in the enrichment

109 h levels of ATP within the viral replication compartment at the expense of a reduction in cytosolic A

110 signaling activity in different subcellular compartments at different timescales.

111 with respect to the disease-driving cellular compartments at the various disease stages.

112 ession of PD-1 +Tim-3+ T cells in the memory compartment before transplantation had increased inciden

113 lant seedlings): a Petri dish containing two compartments (BI Petri dish); two Petri dishes connected

114 ing domain still localize to the presynaptic compartment but do not impair synaptic function in fly n

115 s distributed throughout the somatodendritic compartment but is particularly enriched in the neck and

116 n should be conceptualized not as stratified compartments but as components of an incompletely mixed

117 h compartment is separated from the adjacent compartments by membranous processes from ensheathing gl

118 fectors have been found to enter subcellular compartments by mimicking host targeting sequences.

119 ially its overall exchange between different compartments by nonvesicular transport.

120 mics at the plasma membrane and in endosomal compartments, (c) TCR signal transduction leading to T c

121 The most TKI-insensitive cells of the LSC compartment can be captured within the CD45RA(-) fractio

122 he fusion of autophagosomes to endolysosomal compartments caused an increase in C99 levels.

123 ng disc, Hedgehog (Hh) produced by posterior compartment cells distributes in a concentration gradien

124 ar locations prior to release from posterior compartment cells that express it, and was taken up by b

125 o transcriptomic changes in the lung myeloid compartment characterized by increased expression of pro

126 Additionally, cross-compartment coherence between the middle and ring-little

127 e deterministic epidemic model includes five compartments: colonized and uncolonized patients, contam

128 ication packaging-only care homes) and multi-compartment compliance aids (RR=2.3, 95%CI 1.1 to 4.9, p

129 edication packaging and five used both multi-compartment compliance aids and original medication pack

130 t of original medication packaging and multi-compartment compliance aids on medication administration

131 ween original medication packaging and multi-compartment compliance aids supports the use of the latt

132 ween original medication packaging and multi-compartment compliance aids within care homes that used

133 iginal medication packaging, 1067 from multi-compartment compliance aids).

134 ased into the environment, and the effect of compartment composition on predicted concentrations.

135 ma membrane, endosomes, and lysosomes, these compartments contain other functionally important PIs.

136 expansion of a recycling endosomal signaling compartment containing Sorting Nexin 16 and a reduction

137 Depletion of the memory B-cell compartment contributes to the immunosuppression induced

138 sforming growth factor beta to set up a dual-compartment culture.

139 local chromatin interactions, and chromosome compartments, defined as higher-order interactions betwe

140 stribution of the receptor among the nuclear compartments depends on NCoA-2 and the conformation of t

141 omposition varies greatly within submembrane compartments, different organelle membranes, and also be

142 All loop domains are eliminated, but neither compartment domains nor histone marks are affected.

143 A hierarchically organized cell compartment drives colorectal cancer (CRC) progression.

144 d the accumulation of Tfr cells in the liver compartment during chronic HCV infection and defined the

145 A five-compartment dynamic model is applied to simulate experim

146 navigates both axons and dendrites; in both compartments, dynamic microtubule plus ends enhance dyne

147 revious models and considers ENM releases to compartments (e.g., urban, agriculture) in a manner that

148 urther extracted in the catholyte of a three-compartment electrochemical system, with up to 880 mg of

149 plasma membrane and the endocytic recycling compartment (ERC) are both highly enriched in cholestero

150 deliver cytosolic materials to the lysosomal compartment for degradation through autophagy.

151 s appears to divide, within a membrane-bound compartment for the entire 6-day time course.

152 entified IRAP(+) endosomes as major cellular compartments for the early steps of TLR9 activation in d

153 hese data demonstrate the utility of droplet compartments for the quantitative characterization of bi

154 , as key constituents of the adaptive immune compartment, have variable effects on renal sodium handl

155 d intramitochondrial protein quality control compartment (IMiQ).

156 ically defined hematopoietic stem cell (HSC) compartment in all investigated patients and were also p

157 Evolving work reveals that the MBC compartment in mice and humans consists of distinct subp

158 Because each subcellular compartment in plants contains its own set of ROS-produc

159 expression is up-regulated within the BM HSC compartment in response to G-CSF treatment.

160 mplicate an important contribution by the VE compartment in the severity of anaphylaxis and identify

161 ry signaling from the late endocytic pathway compartments in autoantibody generation.

162 endrimers are directed to the endo-lysosomal compartments in both cell types.

163 We find that spindle compartments in close proximity wait for one another to

164 through controlling acidity of intracellular compartments in eukaryotes.

165 heterochromatin-enriched repressive nuclear compartments in p63-null cells.

166 significantly enhanced the number of acidic compartments in the trophozoites.

167 ion, 454-deep sequencing of liver and plasma compartments in treatment naive patients provides insigh

168 l proteins within endocytic and nonendocytic compartments in VS target T cells.

169 r remodeling in hypoxic PH involves an early compartment-independent activation of lung macrophages t

170 columnar neurons are produced in all spatial compartments independently of spatial input; they innerv

171 It broadly affected the T cell compartment, inhibiting all cell subsets (CD4, CD8, WC-1

172 ogens that replicate within a membrane-bound compartment inside infected host cells known as the Salm

173 , the drug escapes the acidic endo-lysosomal compartment into the cytosol and traffics to its therape

174 lphide amino acid cystine from the lysosomal compartment into the cytosol.

175 Notch1 localization within a tubulovesicular compartment is altered when GSK3beta activity is disrupt

176 he genome within the confines of the nuclear compartment is considered a key contributor to transcrip

177 d, we find that proliferation within the HSC compartment is restricted to CD41-expressing cells that

178 Each compartment is separated from the adjacent compartments

179 impact of ZIKV infection in the human renal compartment is unknown and will require further study.

180 ld, maintain, and define many membrane-bound compartments is encoded by several paralog families, inc

181 unction of these processes in adipose tissue compartments is tightly linked to severe metabolic disor

182 inB2 expression, particularly in the stromal compartment, is associated with reduced metastasis and p

183 l of ROS, as well as the redox state of each compartment, is different at any given time giving rise

184 tion of ABMA is restricted to host-endosomal compartments, it reduces cell infection by pathogens tha

185 y at synaptic terminals to disrupt endosomal compartments, leading to aberrant wiring defects.

186 uch more than other TRP channels in the same compartment, like TRPV1 and TRPA1.

187 the feasibility of applying a dual-input two-compartment liver perfusion model to patients with diffe

188 Renal sinus fat (RSF) is a perivascular fat compartment located around renal arteries.

189 e first time, we show that an integrated two compartment mitochondrial model of beta-oxidation of lon

190 We found that a three compartment model can describe doxorubicin pharmacokinet

191 were analyzed using the validated two-tissue compartment model with arterial plasma input function wi

192 e-activity curve using a reversible 2-tissue-compartment model with blood volume fraction.

193 the beginning of hypercapnia and a 1-tissue-compartment model with flow-dependent extraction correct

194 The stable compartments model postulates that permanent cisternae c

195 rs provide evidence in support of the stable compartments model.

196 (18)F-AV45 VT was determined from 2-tissue-compartment modeling using a metabolite-corrected plasma

197 The aberrant CCSC compartment observed after modulating O-GlcNAc levels is

198 osomal to the zymogen-containing subcellular compartment of acinar cells and activation of CTSD, CTSB

199 on generates a distinct, host-membrane-bound compartment of Chlamydia separate from the original infe

200 hain (LC) accumulates in the somatodendritic compartment of hippocampal neurons, where it forms immob

201 ontrast on a specific protein or subcellular compartment of interest.

202 uctural defects observed in the postsynaptic compartment of mutant NMJs include reduced glutamate rec

203 Specific compartments of [(18)F]DPA-714 (14%) and [(18)F]BR-351 (

204 uminophores within supramolecular polyhedral compartments of a crystalline zeolite-like hydrogen-bond

205 Mitochondria are crucial compartments of eukaryotic cells because they function a

206 standing of their transport in the different compartments of kidneys becomes increasingly important.

207 MDAR-DeltaCa(2+) response in somatodendritic compartments of MNCs of RVH rats, and (2) that a blunted

208 tribution of mRNAs in the cell body and axon compartments of peripheral sensory neurons and the 3' un

209 blood, suggesting the existence of separate compartments of T cells in both tumor and normal breast.

210 ncharacteristic radiology involving multiple compartments of the abdomen.

211 nct signature of ROS levels at the different compartments of the cell.

212 ch is associated with enlarged endolymphatic compartments of the inner ear.

213 ssion differs between the somatic and axonal compartments of the neuron, for both mRNA and microRNA (

214 We observed intense fluorescence in distinct compartments of the protozoa, but not in the bacterial b

215 f Huntington disease (HD)-within the various compartments of the spinal cord and their potential impa

216 atures include (i) large numbers of isolated compartments of tiny volumes that are ideal for single c

217 e parasite lysosomal organelle (the vacuolar compartment or VAC) in turnover of autophagosomes and pe

218 stasis requires tight regulation in specific compartments or niches.

219 cular, it is unknown within what subcellular compartment pathogenic Htt acts and whether the pathogen

220 The method was first tested on a three-compartment phantom as proof-of-concept.

221 tured spinal cord (SC) neurons grown using a compartmented platform followed by next-generation seque

222 usion of Ca(2+) in the pre- and postsynaptic compartments play a critical role in initiating plastic

223 These data suggest that the alpha'3 compartment plays a causal role in the behavioral respon

224 A 2-compartment population model allowed describing rituxima

225 re, we demonstrate that establishment of A/B compartments precedes and defines DNA methylation signat

226 ctin was thought to be the sole cytoskeleton compartment presented in dendritic spines, however, rece

227 Mesh procedures for anterior and posterior compartment prolapse cannot be recommended for primary p

228 g primary transvaginal anterior or posterior compartment prolapse surgery by 65 gynaecological surgeo

229 ith non-mesh repair, mesh repair of anterior compartment prolapse was associated with a similar risk

230 of the pyrenoid matrix as a phase-separated compartment provides a paradigm for understanding its st

231 twork (TGN) to the late endosome/prevacuolar compartment (PVC) and for TGN homotypic fusion.

232 tion domains (TADs) and higher order A and B compartments, reflecting active and inactive chromatin,

233 ognized constituents of distinct subcellular compartments refractory to biochemical isolation and rev

234 o recapitulate the whole CD3(+)CD4(+) T cell compartment remains questionable.

235 hether analogous mechanisms operate in these compartments remains unclear.

236 ns were retained in early and late endosomal compartments, respectively, supporting an impaired endoc

237 ns converge on a small fraction of striosome compartments restricted to the dorsolateral striatum (DL

238 etes prospectively for each cohort and lipid compartment separately using a prespecified analytic pla

239 e epithelial cells-especially in the luminal compartment-should rather be conceptualised as being par

240 ude homeostatic proliferation that maintains compartment size at the expense of partial loss in stemn

241 eterminants, whereas dynein activity is less compartment specific but is more responsive to changes i

242 Collectively our data highlight compartment-specific differences in kinesin activity tha

243 ved hypoxia program, with the development of compartment-specific programs later in the course of the

244 Thus, sepsis unmasks compartment-specific proliferative and apoptotic regulat

245 d inputs from two ears and display rapid and compartment-specific reorganization in response to unila

246 At new cellular locations, access to compartment-specific substrates would enable CHIP to par

247 implications for the development of stromal compartment-specific therapies.

248 tions were positive and negative and in part compartment-specific.

249 ented in MS compared to control cases in all compartments studied (ie, extracellular [p = 0.001], cel

250 cient sensitivity for imaging small neuronal compartments, such as single dendritic spines in brain s

251 e are located to different mitochondrial sub-compartments, suggesting the presence of multiple cAMP/P

252 ppressor cells (MO-MDSCs) within the hepatic compartment suppress inflammation and impair immune surv

253 ere previously associated with intracellular compartments surrounded by a lipid bilayer, have been re

254 chenne muscular dystrophy, polymyositis, and compartment syndrome.

255 s characterized in greater detail in a split-compartment system, using (33) P to quantify mycorrhizal

256 ated targeting of ClC-4 to various endosomal compartment systems via expression of different ClC-3 sp

257 circuits in both the laminar and functional compartments targeted by their axons, and identify two n

258 l began to subdivide into an inner and outer compartment that began to express markers of smooth musc

259 and the IM are separated by the periplasm, a compartment that contains the peptidoglycan.

260 geal coverings accommodate a diverse myeloid compartment that includes parenchymal microglia and peri

261 nas chlororaphis phage 201phi2-1 assembled a compartment that separated viral DNA from the cytoplasm.

262 ing protein cages is a hallmark of bacterial compartments that function as counterparts to eukaryotic

263 uction of proliferation in the hematopoietic compartments that is rapidly lethal in adult animals.

264 eurons within the three functional units, or compartments, that compose the adult MB's alpha lobe, us

265 In spite of prominent changes in the myeloid compartment, the anti-CCR4 antibody did not affect RENCA

266 ar pathogen that resides in a membrane-bound compartment, the inclusion.

267 was to study a particularly vulnerable brain compartment, the late myelinating superficial white matt

268 s the concomitant development of two zygotic compartments, the embryo and the endosperm.

269 proposed PBPK heart model consisted of four compartments: the epicardium, midmyocardium, endocardium

270 vessels, making it a potentially ideal dual-compartment therapeutic target.

271 Regenerative strategies for both compartments therefore constitute a therapeutic avenue.

272 y into the primitive hematopoietic stem cell compartment through the utilization of a modified Rcas/T

273 meric mice lacking TLR2 in the hematopoietic compartment (TLR2KO-->WT) was comparable to TLR2KO mice.

274 The nucleus was the most sensitive cellular compartment to 5-methylTHF accumulation, with levels inc

275 apeutics within a unique, cardiac-restricted compartment to allow sustained drug penetration into the

276 activate FGFR2 in the oligodendrocyte/myelin compartment to increase ERK1/2 activation, which ultimat

277 transporter CD36 from its endosomal storage compartment to the sarcolemma as the primary mechanism o

278 mechanisms used by pathogens to target these compartments to overcome the plant's defense barrier.

279 hy of structural layers, from multi-megabase compartments to sub-megabase topologically associating d

280 Features of genomic organization including compartments, topologically associating domains (TADs) a

281 ccumulated in the cytoplasmic virus assembly compartment (vAC) of infected cells co-localizing with v

282 This specific Rab7(+) compartment was further demonstrated to serve as a major

283 ch about the molecular machinery within each compartment, we are only beginning to understand how the

284 ion potential conduction in different axonal compartments, we investigated the effects of TTX on C-fi

285 he same oncogenic mutations to discrete skin compartments, we show that cell-type-specific chromatin

286 Certain minority subsets within the CD49f(+) compartment were poorly GF-responsive and, among the mor

287 targets and targets localized in subcellular compartments were investigated.

288 g can be achieved using segregated dendritic compartments, which may help to explain the morphology o

289 ics in tumor-bearing mice to include a tumor compartment whose volume depends on the "angiogenic sign

290 undergoes large-scale remodeling to create a compartment with low chromatin density.

291 , time-dependent activation of the lysosomal compartment with no changes in LC3 expression was detect

292 Compared to Y-tube compartments with bovine serum albumin (BSA), GDNF and N

293 ization of hematopoietic stem and progenitor compartments with emergence of functional mIDH2 neutroph

294 d as the reaction progresses, producing more compartments with increased self-replication.

295 results in the production of long spore-like compartments with multiple chromosomes.

296 iguing differences in these samples and cell compartments with respect to the degree of methylation,

297 tacts with mitochondria were abundant in all compartments, with the ER often forming a network that e

298 ontrol will be essential to power subsets of compartments within synthetic tissues or to stimulate su

299 Sampling various compartments within the lower airways to examine human b

300 o specifically recognize damaged or stressed compartments within the mitochondrial network.