ライフサイエンスコーパス: compartmental

1 asure of receptor density) was determined by compartmental (1- and 2-tissue) and noncompartmental (Lo

2 (MRI) in humans to investigate differential compartmental activity in the rectus EOMs during head ti

3 sing the distributed parameter, conventional compartmental, adiabatic tissue homogeneity, and general

4 near mixed effect modelling (AUCNONMEM), non-compartmental analysis (AUC from 0 to infinity [AUC0-inf

5 Isotopomer network compartmental analysis (INCA) is the first publicly avai

6 ding the flux constant of (18)F-FLT based on compartmental analysis (K-FLT), the Patlak influx consta

7 harmacokinetics were described using a three compartmental analysis and gave elimination half lives o

8 estimates of VT in excellent agreement with compartmental analysis and providing high-quality parame

9 (11)C-verapamil and compartmental analysis can estimate P-gp activity at the

10 The K(FLT) for tumors estimated by compartmental analysis had a fair correlation with estim

11 duals with sequential blood samples and upon compartmental analysis of 1 patient with HCMV retinitis.

12 Compartmental analysis of FLT PET image data yielded rob

13 Here we use Arc cellular compartmental analysis of temporal gene transcription by

14 Compartmental analysis of the dynamic scans allowed us t

15 labeled N import into leaf growth zones, and compartmental analysis of the label import data.

16 distribution (VT) derived from a two-tissue compartmental analysis with arterial input function was

17 serotonin, together with serial imaging and compartmental analysis, permits neurotransmitter transpo

18 For compartmental analysis, the arterial input was measured

19 ers were obtained using noncompartmental and compartmental analysis.

20 d parameter model than with the conventional compartmental and adiabatic tissue homogeneity models (P

21 d parameter model than with the conventional compartmental and adiabatic tissue homogeneity models (P

22 flow values determined with the conventional compartmental and adiabatic tissue homogeneity models we

23 The TIM-1 is a multi-compartmental and dynamic in vitro system, simulating di

24 Biscuits were digested using a multi-compartmental and dynamic system that simulates the main

25 Compartmental and graphical models using arterial input

26 Analyses were performed on a compartmental and knee level.

27 Pharmacokinetic parameters were estimated by compartmental and noncompartmental methods.

28 elation with influx parameters obtained from compartmental and Patlak analyses.

29 In this work, compartmental and spatial modeling of rule-based models

30 than 300 simulations have been run based on compartmental and three-dimensional spatial versions of

31 f BMCs (YFP(+) and YFP(-)) was determined in compartmental and transwell cultures of dissociated TG c

32 ompartments and demethylation of large inter-compartmental backbones.

33 ability to acutely and selectively influence compartmental behavior as exemplified here for endomsome

34 ingression; however, the pathways that link compartmental behaviors with cortical furrow ingression

35 mu-1,2-peroxo dicopper(II) complex (2) of a compartmental bis(tetradentate) pyrazolate-based ligand

36 easure circulatory responses (peripheral and compartmental blood flow, venous capacity, and microvasc

37 FLRT1 is expressed at brain compartmental boundaries and FLRT2 is expressed in a sub

38 thalamus and prethalamus, revealing multiple compartmental boundaries within the mouse diencephalon.

39 ences in Hox expression often correlate with compartmental boundaries, but the genetic basis for thes

40 artments and the relevant fascicles defining compartmental boundaries.

41 stripe of cells along the anterior-posterior compartmental boundary is well established, the mechanis

42 Wingless pathway is graded and peaks at each compartmental boundary, Tnks is dispensable for signalin

43 ich upon solvent evaporation can yield multi-compartmental capsules or hierarchically structured poro

44 Our results suggest that compartmental changes in Ca(2+) concentration regulate g

45 esults are consistent with the concepts of a compartmental circuit organization, a bilaterally couple

46 d determined that 20% of PC inputs to a full compartmental CN neuron model need to be rate-comodulate

47 s, corresponding to liposomes with different compartmental configurations, were obtained.

48 ical rectus EOMs did not exhibit significant compartmental contractile changes during head tilt.

49 Compartmental Cu(+) levels appear independently controll

50 ns(4,5)P(2)) appears to act as the principal compartmental cue for AP-2 placement at the plasma membr

51 In compartmental culture experiments, neurite outgrowth tow

52 Compartmental culture of trigeminal ganglion neurons was

53 Compartmental culture of trigeminal ganglion neurons was

54 n in neurites occurred after BAK addition to compartmental cultures of dissociated trigeminal ganglio

55 We used compartmental cultures of dissociated trigeminal ganglio

56 Thus, CaMKII could decode compartmental dendritic Ca(2+) transients to support rem

57 A compartmental deterministic model was used to estimate p

58 on epidemiological estimates, we developed a compartmental difference-equation model of the TB/HIV ep

59 The presence of compartmental differences at one or more of the identifi

60 Compartmental differences in human immunodeficiency viru

61 Compartmental differences in T(E)-cell- and H. pylori-me

62 These results suggest compartmental differences of T cell activation pathways

63 cost or its intracellular concentration and compartmental distribution.

64 The results suggest that compartmental domains are responsible for domain structu

65 Architectural proteins insulate compartmental domains by reducing interaction frequencie

66 In mammals, compartmental domains exist alongside CTCF loop domains

67 chromatin is organized into domains we term compartmental domains that correspond precisely with A/B

68 third-instar wing blade primordia devoid of compartmental dpp expression maintain relatively normal

69 D-loaded DNA icosahedra allows us to monitor compartmental dynamics along endocytic pathways.

70 A previously developed compartmental EC-SMC model is modified to include MPs as

71 A weaker compartmental effect was suggested for MR.

72 tailed molecular description of the distinct compartmental effects of diabetes on the PNS that could

73 Incorporating these data into simple compartmental epidemiological models is often challengin

74 Traditional compartmental epizootic models, which are relatively eas

75 predominance during acute primary infection, compartmental equalization occurred in the CMV-specific

76 However, our inability to influence these compartmental events in a spatially restricted and acute

77 to ribosomal protein L17 and an inversion of compartmental exposure.

78 s may be used to compare antiretroviral drug compartmental exposure; they deserve longitudinal studie

79 Overall, these results demonstrate that the compartmental expression of Ubx and abd-A is established

80 A-induced dyskinesias, and have differential compartmental expression patterns in the striatum, we su

81 ation patterns also reflect species-specific compartmental features.

82 We demonstrate that directional compartmental flow of intracellular Ca(2+) underlies dea

83 thostatic tolerance resulting from decreased compartmental fluid shifts in response to head-up tilt a

84 l support for the proposal that differential compartmental function in horizontal rectus EOMs contrib

85 Collectively, our results define contrasting compartmental functions for TLR9 and MyD88, and suggest

86 In this article a compartmental genetic-epidemiological model was develope

87 Analysis of longitudinal or compartmental HCMV diversity revealed various patterns:

88 om bellies and tendons exhibited substantial compartmental independence when loaded in the physiologi

89 Here, we inspect the error growth of a compartmental influenza model and find that a robust err

90 the authors address the error structure of a compartmental influenza model, and develop a new improve

91 her than by differing sources of laminar and compartmental input from V1.

92 partments, the kinetics of equilibrium water compartmental interchange are competitive.

93 Specifying myocardial compartmental involvement may then implicate cellular/mo

94 kyrin-based membrane adaptors might serve as compartmental labels, which contribute to subcellular sy

95 phenotypes and dysregulating airspace/blood compartmental levels of PMNs and cytokines.

96 A compartmental ligand scaffold HL with two beta-diketimin

97 To determine whether local compartmental loss of a phosphoinositide disrupts the no

98 entional average absorbed dose assessment, a compartmental macrodosimetric approach that accounts for

99 We developed a compartmental mathematical model of HIV transmission and

100 bacterial population is conceptualized as a compartmental mathematical model to describe changes in

101 measures of intracranial volume, brain size, compartmental measures of gray matter and white matter,

102 rane trafficking, by serving as signposts of compartmental membrane identity.

103 parameters were quantified using a 2-tissue compartmental model (2TC) as well as a 2TC with an extra

104 ntion, we developed a multi-group stochastic compartmental model (a continuous time Markov chain mode

105 On the basis of these measurements, a compartmental model (M) that accounts for the contributi

106 Compartmental model analysis was performed to estimate t

107 ned using a reversible plasma input function compartmental model and the cerebellum as a reference re

108 We adapted an empirically calibrated dynamic compartmental model and used it to assess the discounted

109 A morphologically realistic compartmental model capable of reproducing the observed

110 To do so, we develop a compartmental model composed of a two-sex age-structured

111 community's prevalence with a deterministic compartmental model focusing on heterosexual transmissio

112 Our aim was to determine an appropriate compartmental model for tracer kinetics, evaluate a refe

113 We have developed and tested a compartmental model for use with the 64Cu-DOTA-RGD PET t

114 ce, the Susceptible/Infected/Recovered (SIR) compartmental model has successfully been applied to dif

115 rder of magnitude differences from a regular compartmental model ignoring tracer diffusion limitation

116 A simple compartmental model is developed for investigating the m

117 ameter sensitivity, but the use of a dynamic compartmental model limited the exploration of structura

118 Using a detailed compartmental model of a layer 5 PN, and an improved met

119 ng these electrophysiological results into a compartmental model of developing excitatory neurons dem

120 The model incorporates an SIS compartmental model of disease transmission into a game

121 this shortcoming by producing a dynamic, six-compartmental model of DNA methylation levels based on t

122 Using a multi-compartmental model of DNA methylation, we show that par

123 We developed a deterministic compartmental model of heterosexual HIV transmission in

124 A dynamic age-structured compartmental model of measles transmission was used to

125 A compartmental model of mouse thrombopoiesis and erythrop

126 Based on a compartmental model of spine calcium dynamics, we propos

127 We developed a compartmental model of TB in NYC, parameterized with det

128 We constructed a steady-state compartmental model of TB in Rio de Janeiro, replicating

129 A compartmental model of the dynamics of red blood cell pr

130 Our goal is to build the next-generation two-compartmental model of the immune response to provide a

131 We develop and analyse a flexible compartmental model of the interaction between a plant h

132 membrane properties were incorporated into a compartmental model of the type II neuron to demonstrate

133 e properties of these neurons and to build a compartmental model of their electrotonic structure.

134 The developed compartmental model of thrombopoiesis and erythropoiesis

135 We constructed a dynamic, compartmental model representing incidence of infection

136 METHODS AND We developed a stochastic compartmental model representing the natural history and

137 Simulations using a compartmental model reproduced physiological results and

138 A compartmental model structure was developed, and values

139 Simulations using a neuron compartmental model support the idea that the prepulse e

140 The compartmental model takes into account the pharmacokinet

141 , and v(e) were higher with the conventional compartmental model than with the adiabatic tissue homog

142 The aim of this study was to evaluate a compartmental model that accounts for the effect of endo

143 A compartmental model that allowed for interindividual dif

144 olabeled RGD peptides, we have constructed a compartmental model that can describe the time-activity

145 We developed a deterministic compartmental model that links the care pathway to disea

146 idential care facility by using a stochastic compartmental model to address the question of whether c

147 We calibrated a compartmental model to data from drug resistance surveys

148 For 2015 live births, we used a compartmental model to estimate (1) exposure to maternal

149 c tracer data were then fit to a dual-tracer compartmental model to estimate the density of receptors

150 The authors used a compartmental model to estimate the duration of untreate

151 rmed using an irreversible 1-plasma 2-tissue compartmental model to estimate the kinetic rate constan

152 We developed a deterministic compartmental model to predict HIV incidence among India

153 We develop a compartmental model to study epidemic outcomes of elevat

154 We developed an age-structured compartmental model to study the spread of CA-MRSA at th

155 We used a transmission-dynamic compartmental model to synthesise evidence from surveill

156 18)F-fluoride PET data were compared: a 4k 3-compartmental model using nonlinear regression analysis

157 linear regression analysis (K(i-4k)), a 3k 3-compartmental model using nonlinear regression analysis

158 collected experimental data and formulated a compartmental model using ordinary differential equation

159 An irreversible 2-tissue-compartmental model was implemented to simulate clinical

160 Methods: An irreversible 2-tissue-compartmental model was implemented to simulate clinical

161 tion criterion, we developed a deterministic compartmental model with both replacement (cohort) and l

162 PET data were analyzed with a 2-tissue compartmental model with calculation of rate constants f

163 analysis (3 variants of the Hawkins 3-tissue compartmental model, 3 variants of spectral analysis, de

164 We formulate a compartmental model, constrain its parameters by experim

165 onlinear least-squares fitting of a 2-tissue-compartmental model, reference tissue modeling, and late

166 Using a detailed multi-compartmental model, we show this physiological setup to

167 dor and compare our new model with a typical compartmental model, which highlights the regime in whic

168 ing a susceptible-exposed-infectious-removed compartmental model, with gamma-distributed transition t

169 tes of tracer transport and metabolism, with compartmental model-derived time-activity data closely f

170 ingle cells followed the standard two-tissue compartmental model.

171 2010 to 2050 using a dynamic, age-structured compartmental model.

172 hes, meta-analyses, and modeling including a compartmental model.

173 netic parameters were calculated using a non-compartmental model.

174 Design: Empirically calibrated dynamic compartmental model.

175 usceptible-exposed-infected-recovered (SEIR) compartmental model.

176 ume of distribution (VT) was estimated using compartmental modeling (1- and 2-tissue configurations)

177 Compartmental modeling and Patlak analysis of (11)C-GMO

178 With the use of compartmental modeling and stable isotope technology, we

179 raction with PET using 1-(11)C-glucose and a compartmental modeling approach that takes into account

180 Here, we use a compartmental modeling approach to identify factors that

181 Using compartmental modeling based on simultaneous intravenous

182 livery and (11)C-PiB retention that included compartmental modeling distribution volume ratio (DVR),

183 on of the regional fraction of blood (FB) if compartmental modeling is used to quantify (18)F-FDG pul

184 Compartmental modeling is used to show that the primary

185 Compartmental modeling of (11)C-GMO kinetics in the monk

186 Compartmental modeling of (11)C-GMO kinetics yielded est

187 PBF and FB were measured with PET and compartmental modeling of (15)O-H2O and (18)F-FDG kineti

188 te the use of FB to assess PBF, with PET and compartmental modeling of (15)O-H2O kinetics as a refere

189 aim of this study was to investigate whether compartmental modeling of 1-(11)C-glucose PET kinetics c

190 Compartmental modeling of [(18)F]1 kinetics provided net

191 from this technique typically requires multi-compartmental modeling of dynamic data, and results are

192 Compartmental modeling of the PET data was performed usi

193 ust determination of CMRGlc using either the compartmental modeling or the Patlak approach, even with

194 e tissue were found to correlate highly with compartmental modeling outcomes.

195 he proposed method and make comparisons with compartmental modeling parametric maps and SUV segmentat

196 l to the soma than CC synapses, but detailed compartmental modeling predicted that dendritic filterin

197 beled 22:6n-3 in 11 newborn infants by using compartmental modeling procedures.

198 (13)C-Lycopene combined with physiologic compartmental modeling provides a strategy for following

199 Compartmental modeling resulted in good fits, and the 2-

200 Pharmacologic tests and compartmental modeling showed that these effects were pr

201 Some studies have used compartmental modeling to determine tracer binding kinet

202 blood data, brain uptake was quantified with compartmental modeling to estimate the rates of entry in

203 have used two-photon glutamate uncaging and compartmental modeling to reveal a gradient of nonlinear

204 mpartmental analysis of these data and apply compartmental modeling to these human verapamil imaging

205 Compartmental modeling was applied to estimate rate cons

206 Compartmental modeling was performed using the corrected

207 isotope tracer infusions in conjunction with compartmental modeling were used to evaluate IHTG conten

208 mate binding parameters in 10 brain regions: compartmental modeling with 1- and 2-tissue compartment

209 Using compartmental modeling with input of both (18)F-FCWAY an

210 We calculated V(T) using compartmental modeling with serial measurements of uncha

211 zed factor analysis of dynamic sequences and compartmental modeling yields estimates of parameters of

212 ngs in gerbil brainstem slices together with compartmental modeling, we found that activation of K(v)

213 Using compartmental modeling, we point out a possible function

214 alyzed these dynamic biodistribution data by compartmental modeling.

215 ion volume (V(T)) using the gold standard of compartmental modeling.

216 myocardial clearance analysis (oxidation) or compartmental modeling.

217 This work sets a new benchmark for detailed compartmental modeling.

218 upporting this possibility, we found both in compartmental models and electrophysiological recordings

219 Compartmental models and Logan graphical methods enabled

220 ction and it was straightforward to apply on compartmental models and multiple data sets.

221 Compartmental models are appealing because of their simp

222 Compartmental models are the theoretical tool of choice

223 Our results indicate under which conditions compartmental models can and cannot be used, why this is

224 In the kidneys, compartmental models did not adequately fit the experime

225 Irreversible-uptake compartmental models fitted the kinetics of (18)F-FHNP u

226 tilising crowd-behaviour research to improve compartmental models in crowded situations.

227 cover other hidden consequences of employing compartmental models in these contexts.

228 Fitting diffusion-limited data with regular compartmental models led to parameter estimate bias in a

229 By fitting detailed compartmental models of Golgi cells to their somato-dend

230 ls, we could reproduce these statistics with compartmental models of varying complexity.

231 The PBPK model comprised compartmental models of vessels and organs unique to eac

232 twork simulations of biophysically realistic compartmental models of VS cells.

233 Hodgkin-Huxley-type compartmental models revealed that the distinct firing m

234 Compartmental models support the view that these results

235 s approach could assist parameter choices in compartmental models that do not explicitly model the sp

236 The compartmental models used to study epidemic spreading of

237 We compare two compartmental models with different mosquito representat

238 considered spatial organization or have used compartmental models with minimal spatial resolution.

239 PET data were analyzed with 1- and 2-tissue compartmental models, the simplified reference tissue mo

240 Importantly, in addition to formulation of compartmental models, this now permits VCell users to se

241 eocortical slices and in simple and detailed compartmental models, with equivalent results: somatic i

242 ves were analyzed using various plasma input compartmental models.

243 A compartmental multimedia model was developed to enable e

244 We systematically analyze when compartmental ODE models can be used in these contexts,

245 of (18)F-CPFPX were well described by either compartmental or noncompartmental models based on arteri

246 lood, intestine and brain, have a similar bi-compartmental organization and that stem cells might wor

247 pecific distribution of GM130 determines the compartmental organization of dendritic Golgi in dendrit

248 Golgi outposts as well as the regulation of compartmental organization of Golgi in general.

249 It is increasingly recognized that the compartmental organization of signaling processes has a

250 , thus providing important insights into the compartmental organization of the early endocytic pathwa

251 We further show that compartmental organization regulates the role of Golgi i

252 ess this topic by focusing on morphogenesis, compartmental organization, proliferation and cell linea

253 ks of signalling and metabolic pathways with compartmental organization.

254 Recently, intracellular trafficking and compartmental partitioning have been identified as mecha

255 ell domains based on dynamic, size-dependent compartmental partitioning that does not require diffusi

256 erability related to a dependence on a cross-compartmental pathway of pyrimidine metabolism in an agg

257 We show that compartmental pH is an important determinant of thermody

258 ocation of auxin is linked to its effects on compartmental pH.

259 hildren with tuberculosis were modeled using compartmental pharmacokinetic analyses.

260 This model is combined with a compartmental pharmacokinetic model to explore the effec

261 In a two-compartmental pharmacokinetic model, body weight was the

262 Compartmental pharmacokinetic modeling was conducted usi

263 Linear compartmental pharmacokinetic models of increasing compl

264 Two compartmental pharmacokinetic models were tested: the 2-

265 Compartmental pharmacokinetic parameters of isoniazid, r

266 Compartmental pharmacokinetics analysis was performed on

267 We demonstrate that compartmental placement of non-parenchymal cells relativ

268 alanine-derived compounds is a complex multi-compartmental process using phenylalanine synthesized pr

269 rotein (C1QBP; also known as p32) is a multi-compartmental protein whose precise function remains unk

270 ns) (-34% relative change, P=.003), backflow compartmental rate constant extravascular and extracellu

271 activity, or Ki-67 expression and any of the compartmental rate constants.

272 modeling of cancer cell MMP-9 reflected by a compartmental redistribution of this gelatinase, in whic

273 I4KIIIbeta and PI4KIIalpha contribute to the compartmental regulation of PI4P synthesis within the Go

274 hat in the absence of stochastic extinction, compartmental repopulation always predicts a larger numb

275 nvestigate the difference made by assuming a compartmental repopulation signal, and a global repopula

276 with global repopulation can exceed that for compartmental repopulation.

277 part of the whole viral population and that compartmental reservoirs could have implications in futu

278 15 patients and in most of the patients with compartmental samples, whereas a switch of the major HCM

279 Compartmental second messenger signaling and interendoth

280 Low molecular copy number, arising from compartmental segregation and slow diffusion between com

281 By contrast, compartmental segregation is preserved and even reinforc

282 m rat choroid plexus epithelia, leading to a compartmental shift of Fe from the blood to the CSF.

283 lts suggest that Notch1 participates in a bi-compartmental signaling network that controls homeostasi

284 ial simulations and network-free agent-based compartmental simulations, the BioNetGen and NFSim engin

285 Using compartmental simulations, we examined the effects of va

286 nervation territories, suggesting functional compartmental specialization.

287 monstrate a previously unrecognized systemic compartmental specificity for the regulation of liver:bo

288 al equations with diffusion approximation (a compartmental stochastic mathematical model) to research

289 ions are valuable for the formation of multi-compartmental structures.

290 udies indicate that outputs from V1 are less compartmental than previously thought, making it difficu

291 ven estimation of parametric images based on compartmental theory (DEPICT) analysis, graphical analys

292 support the novel function of COPI in inter-compartmental trafficking of RNA.

293 ostasis requires transmembrane transport and compartmental trafficking while maintaining the cell ess

294 of developmental processes including segment compartmental transformation, apoptosis, and suppression

295 We created a compartmental transmission model of TB in a representati

296 tion and prediction framework for stochastic compartmental transmission models of epidemics.

297 pH increase reflects the pH gradient during compartmental transport within target cells, potential K

298 escribing the spread of disease have been of compartmental type, based on the assumption that populat

299 or each subject and MR-AC map, the following compartmental volumes were calculated: total body, soft

300 increased placental weight, but not total or compartmental volumes.