ライフサイエンスコーパス: compartmentalization

1 excitatory synapses due to spine electrical compartmentalization.

2 s an important example of transient membrane compartmentalization.

3 e phenotypes, which suggest their functional compartmentalization.

4 gh modulating Rac1 activity and Akt membrane compartmentalization.

5 blishment of post-mitotic nucleo-cytoplasmic compartmentalization.

6 n of Ctn RNA, they modulate its intranuclear compartmentalization.

7 cal stress, even without loss of subcellular compartmentalization.

8 s and result in intermittent loss of nucleus compartmentalization.

9 ed for free redox mediators or anode/cathode compartmentalization.

10 n dissecting the mechanisms of cell membrane compartmentalization.

11 e, age-dependent cell division profiles, and compartmentalization.

12 intenance of their structural and functional compartmentalization.

13 d neurocognitive disorder (HAND) may reflect compartmentalization.

14 l in signaling cascades through localization/compartmentalization.

15 y for proper post-mitotic nucleo-cytoplasmic compartmentalization.

16 docytosis, spindle positioning, and cellular compartmentalization.

17 ily required for correct PcG protein nuclear compartmentalization.

18 logy that predict an increase in biochemical compartmentalization.

19 ther such specificity is necessary for Golgi compartmentalization.

20 flare, indicating that Cdc5 is needed for NE compartmentalization.

21 e proteins irrespective of their subcellular compartmentalization.

22 for Reelin signaling in specifying dendritic compartmentalization.

23 a continuum of mechanisms to ensure nuclear compartmentalization.

24 by this UPR branch, is responsible for this compartmentalization.

25 ation strategies: enzyme co-localization and compartmentalization.

26 flow (EOF) or hydrodynamic flow for droplet compartmentalization.

27 nature of nanodisc membranes that offers no compartmentalization.

28 an be used to study rate enhancements due to compartmentalization.

29 large enough to generate significant voltage compartmentalization.

30 separation being the driving process behind compartmentalization.

31 tolerance mechanism involving intracellular compartmentalization.

32 ABA was also subjected to a target-dependent compartmentalization.

33 nt and as diffusion barriers for subcellular compartmentalization.

34 ncer cells, they decreased ephrin B1-induced compartmentalization.

35 s at a resolution commensurate with cellular compartmentalization.

36 in nonnatural SIV hosts, do not exhibit this compartmentalization.

37 d development of caveolin-mediated signaling compartmentalization.

38 h the control of mRNA stability, cytoplasmic compartmentalization, 3' UTR length and translational ef

39 and FB pathways provides further evidence of compartmentalization; 5) FF pathways have higher weights

40 propose a common framework for describing AL compartmentalization across Hymenoptera and discuss poss

41 ink between glutathione oxidation and copper compartmentalization allows for rapid metabolic adjustme

42 Such distinct compartmentalization allows the confinement of cyclic nu

43 Compartmentalization allows the oxidation products for e

44 egrate these alternative models of prebiotic compartmentalization and develop a hybrid protocell mode

45 one by examining the effects of localization/compartmentalization and diffusion of enzymes and substr

46 are typical of eukaryotes, such as cytosolic compartmentalization and endocytosis-like macromolecule

47 l blockade of HCN channels decreased voltage compartmentalization and enhanced the generation and spr

48 D genome characterized by extensive physical compartmentalization and insulation on the one hand and

49 ional, quantitative analysis of human T cell compartmentalization and maintenance over six decades of

50 ted spatial and temporal map of human T cell compartmentalization and maintenance, supporting distinc

51 ergence of eukaryotes provided the necessary compartmentalization and membranous environment for RNA

52 nflammation causes the decline of intestinal compartmentalization and microbiota dysbiosis, limiting

53 Moreover, compartmentalization and ordered-structures composed of

54 Compartmentalization and polarized protein trafficking a

55 lly link analogous cisternae to ensure Golgi compartmentalization and proper processing.

56 lts reconcile cell-type-specific sub-nuclear compartmentalization and replication timing with develop

57 tein interactions are important in providing compartmentalization and specificity in cellular signal

58 tability is further corroborated by impaired compartmentalization and stabilization of miRNP componen

59 ellular functions, which include signalling, compartmentalization and stabilization.

60 that E1B-55K and E4-ORF3 specify the nuclear compartmentalization and structure of SUMO2/3-associated

61 s with control over their relative distance, compartmentalization and substrate diffusion paths.

62 The study of intracellular metal ion compartmentalization and trafficking involved in cellula

63 hanisms, providing invaluable models for the compartmentalization and transfer mechanisms required an

64 LDAP1 was required for proper neutral lipid compartmentalization and triacylglycerol degradation dur

65 in breast carcinoma cells promotes metabolic compartmentalization and tumor growth with a mitochondri

66 s are likely influenced by receptor density, compartmentalization, and as-yet unknown binding partner

67 gene regulation that enable local functions, compartmentalization, and cooperativity, which makes the

68 dence pertaining to the biomass composition, compartmentalization, and flux constraints.

69 elieved through Na(+) influx restriction and compartmentalization, and osmotic homeostasis reestablis

70 erapies, and how consideration of Trm, their compartmentalization, and specificity can enable improve

71 tleneck events associated with infection and compartmentalization, and strong purifying selection all

72 llular processes: vesicle traffic, signaling compartmentalization, and the second messenger Ca(2+) We

73 amentous structure that supports the nuclear compartmentalization appears to be unnecessary, since th

74 Mechanisms of prebiotic compartmentalization are central to providing insights i

75 r challenges addressed through intracellular compartmentalization are toxic or volatile pathway inter

76 se newer findings further implicate anatomic compartmentalization as a generalized mechanism for long

77 and engineering of biochemical pathways with compartmentalization, at the core of systems and synthet

78 [Ca(2+)]i was elevated in FHM1, with loss of compartmentalization between synapses and neuronal shaft

79 king transcripts that undergo more extensive compartmentalization by fluorophore-labeling U1 small nu

80 It is now clear that in addition to compartmentalization by the individual spine, subcompart

81 The maintenance of nuclear compartmentalization by the nuclear envelope and nuclear

82 t that it has a role in intracellular copper compartmentalization by transferring cytosolic copper to

83 shape of the active colloidal cell and drive compartmentalization by varying the details of the bound

84 arding the molecular mechanisms that utilize compartmentalization by which the mycobacterial cell may

85 Axon/dendrite compartmentalization can be attributed to neuronal polar

86 Such allele separation and allelic compartmentalization can be found as late as the 8-cell

87 ses share five fundamental properties (i.e., compartmentalization, carbon input through photosynthesi

88 s highlight how notions of membrane-mediated compartmentalization, chemical enrichment and internaliz

89 erns of the human genome, such as chromosome compartmentalization, chromosome territories, co-localiz

90 Herein, we take the compartmentalization concept to the synthetic realm and

91 ve X chromosomes adopt different folding and compartmentalization configurations.

92 t for the other elements, suggesting that Mg compartmentalization could be a significant trait of the

93 ocalization is largely intracellular and its compartmentalization could contribute to its sustained a

94 e wider and shorter, indicating that synapse compartmentalization decreases substantially with age.

95 al flow of information in neurons depends on compartmentalization: dendrites receive inputs whereas a

96 The mechanisms by which metabolic compartmentalization develop in tumors are poorly charac

97 ther physical and chemical constraints (like compartmentalization, differential diffusion, selective

98 l noncoding RNAs, but also their cytoplasmic compartmentalization during spermiogenesis.

99 function and fate is determined by anatomic compartmentalization during the early immune contraction

100 virus (HIV/SIV) sequences within the brain (compartmentalization) during infection is hypothesized t

101 It remains unclear, however, how compartmentalization dynamics change over time.

102 e actin cytoskeleton in controlling receptor compartmentalization, dynamics, and clustering as a mean

103 Crucially, the compartmentalization enabled the formation of two adjoin

104 al evidence indicating that such spontaneous compartmentalization exploits general features of the ph

105 Whether this compartmentalization facilitates the preferential interc

106 conceptualizes a new pathway to spontaneous compartmentalization for a wide range of inorganic NPs i

107 bly diverse range of organelles that provide compartmentalization for distinct cellular functions and

108 The ubiquity of subsurface water compartmentalization found here, and the segregation of

109 To date, direct visualization of such compartmentalization has been achieved only by electron

110 A striking neurochemical form of compartmentalization has been found in the striatum of h

111 ich membrane microdomains (lipid rafts), its compartmentalization has not been demonstrated in intact

112 nary mechanism responsible for HIV/SIV brain compartmentalization has not been thoroughly investigate

113 w, we will discuss the evidence for acyl-CoA compartmentalization, highlight the key modes of acyl-Co

114 ysis of the main responsible genes for Na(+) compartmentalization (i.e. Na(+)/H(+) EXCHANGERs, SALT O

115 t reveal ganglionic subdivisions or physical compartmentalization in any of these microscopic brains.

116 Compartmentalization in cells is central to the spatial

117 Compartmentalization in cellular organelles can isolate

118 nesis and human immunodeficiency virus (HIV) compartmentalization in cerebrospinal fluid (CSF) and be

119 ommon organizational principles underlie TAD compartmentalization in deuterostome evolution.

120 PM sub-compartmentalization in domains is thought to orchestrat

121 Compartmentalization in droplets accelerated the develop

122 Carbon-flow compartmentalization in E. oleoabundans was modeled usin

123 ding proteins, are key regulators of spatial compartmentalization in fungi and other eukaryotes.

124 transporters (ZnTs) mediate zinc efflux and compartmentalization in intracellular organelles; thus,

125 over the course of infection, brain sequence compartmentalization in macaques with SIV-associated CNS

126 a viable mechanism for dynamic intracellular compartmentalization in membraneless organelles.

127 The recognition of the increasing role of compartmentalization in metabolic engineering is highlig

128 s to investigate the role of GIV subcellular compartmentalization in regulating its ability to promot

129 Furthermore, mGluR2-mediated dendritic compartmentalization in SACs is important for the functi

130 emonstrated a role for differential membrane compartmentalization in selective agonist-induced degrad

131 nd human immunodeficiency virus type 1 (HIV) compartmentalization in semen.

132 to determine the particular role for ciliary compartmentalization in sensory reception and signaling

133 mechanisms that underlie the role of ciliary compartmentalization in signaling might provide unique a

134 This regional compartmentalization in the coagonist identity is associ

135 els feature a surfactant boundary, providing compartmentalization in the form of a micelle or vesicle

136 edulla, emphasizing the importance of thymus compartmentalization in the generation of both diverse a

137 We aimed to understand how spatial compartmentalization in the plasma membrane might contri

138 e natural selection mechanisms that occur by compartmentalization in vivo, we developed a technique b

139 solve this biological complexity of membrane compartmentalization in vivo.

140 ial regulator of axon branching and neuronal compartmentalization in vivo.

141 parated from each other and display distinct compartmentalization in zygotes.

142 It combines microfluidic compartmentalization, in situ allele-specific PCR, and f

143 he kinetic consequences of sequential enzyme compartmentalization into model liquid organelles in a c

144 Compartmentalization is a fundamental ingredient, centra

145 At the cellular level, compartmentalization is a key aspect of the functioning

146 PCs) is essential for cell function; loss of compartmentalization is associated with cancers, laminop

147 that misexpresses cdc25a, we show that this compartmentalization is critical for the formation of th

148 The development and maintenance of protein compartmentalization is essential for neuronal function.

149 utants with disorganized ER, we show that ER compartmentalization is independent of the morphological

150 Compartmentalization is one of the defining features of

151 mechanisms responsible for overcoming immune compartmentalization is valuable for designing vaccinati

152 nd characterize the expression regimes where compartmentalization leads to improved product titre.

153 larly important in neurons in light of their compartmentalization, length of axonal processes, and hi

154 This compartmentalization likely facilitates cargo degradatio

155 Our findings suggest that this nuclear compartmentalization may play a critical role in the exp

156 en topologically associating domains and A/B compartmentalization, measurements of genome accessibili

157 s regarding the role that defects in ciliary compartmentalization might play in disease pathogenesis.

158 In eukaryotes, compartmentalization minimizes inevitable enzyme inhibit

159 d an age-dependent loss of nucleocytoplasmic compartmentalization (NCC) in donor fibroblasts and corr

160 nd that both establishment of TADs and their compartmentalization occur during early G1, within the s

161 secondary lymphoid tissues or whether virus compartmentalization occurs in the absence of CTL.

162 This compartmentalization of acyl-CoAs resulted in both an ex

163 m this cellular melange arises a biochemical compartmentalization of areas termed striosomes and extr

164 and physiological importance of this spatial compartmentalization of autophagy in the neuronal develo

165 In vitro compartmentalization of biochemical reaction networks is

166 Membrane fission, which facilitates compartmentalization of biological processes into discre

167 Circadian clocks allow the temporal compartmentalization of biological processes.

168 Subcellular compartmentalization of biomolecules and their reactions

169 Our findings highlight an essential compartmentalization of both PKA and GSK3beta by GSKIP,

170 We investigated the role of mitochondria in compartmentalization of Ca(2+) We found that mitochondri

171 gradients, and can result in the cytoplasmic compartmentalization of Ca2+ without requiring a partiti

172 Thus, we provide evidence for a compartmentalization of carotenoid metabolism that preve

173 The compartmentalization of cell cycle regulators is a commo

174 and subsequent division, leading to unequal compartmentalization of cellular/extracellular component

175 Consistent with a major role in compartmentalization of complex routes, individual retro

176 Intracellular compartmentalization of cooperating enzymes is a strateg

177 By directing septin-mediated compartmentalization of cortical actomyosin, PCP protein

178 Compartmentalization of designed metabolic pathways with

179 orescently image and map the segregation and compartmentalization of different cells during the forma

180 lar, while mouse embryos first exhibited sub-compartmentalization of different histone modifications

181 endritic shaft, has been shown to facilitate compartmentalization of electrical and cytoplasmic signa

182 y xylem, which may favor rapid refilling and compartmentalization of embolisms that occur in small ve

183 Compartmentalization of enzymes into organelles is a pro

184 , this is the only report to date dissecting compartmentalization of eosinophil recruitment as it unf

185 Our results show a striking degree of compartmentalization of epigenetic and genomic features

186 A compartmentalization of function begins with the segrega

187 This adds further impetus to understanding compartmentalization of function in the nucleus.

188 pace, raising the question of how functional compartmentalization of gene expression is achieved.

189 apsulation to enable the modular, controlled compartmentalization of genetic circuits and cascades.

190 Mechanisms determining dynamic compartmentalization of Gpr161 in cilia define a new par

191 y complex between Gpr161 and RI promotes the compartmentalization of Gpr161 to the plasma membrane.

192 Sequential compartmentalization of Hb by erythrocytes and scavenger

193 Size-selective compartmentalization of Hb functions as a substitute for

194 Our study provides evidence of compartmentalization of hydrocarbon-degrading capacity i

195 This compartmentalization of immune cells in the FRT was supp

196 cells per assay, circumventing the need for compartmentalization of individual cells.

197 of centromeres at the spindle pole body and compartmentalization of individual chromosomes within th

198 The development of compounds to disrupt the compartmentalization of individual PDE4 isoforms by targ

199 ation could provide a physical mechanism for compartmentalization of inorganic catalysts in primitive

200 Much less data are available on the compartmentalization of its closest homolog, cGMP-depend

201 uncover compelling evidence for the cellular compartmentalization of key chemical transmission pathwa

202 functional specificity involves subcellular compartmentalization of kinase function by scaffolding p

203 ne known to control lymphocyte migration and compartmentalization of lymphoid tissues in mammals, div

204 chemiluminescence and demonstrated that the compartmentalization of LYS in droplets also comprising

205 gregated upon CTCF depletion, revealing that compartmentalization of mammalian chromosomes emerges in

206 Compartmentalization of metabolic pathways to particular

207 Compartmentalization of metabolism complicates the inter

208 Disruption of the RC reveals extensive compartmentalization of mitochondrial metabolism and sig

209 miRNAs appear to control cytoplasmic compartmentalization of mRNAs based on 3' UTR length.

210 e triple serine motif regulates intranuclear compartmentalization of murine Olig2.

211 The transgenic plants show better tissue compartmentalization of Na(+) and higher ROS scavenging

212 es in regulating the strength, kinetics, and compartmentalization of neuronal SEPs.

213 The remarkable polarity and compartmentalization of neurons raises questions about t

214 ture spines may contribute to spine-specific compartmentalization of neurotransmitter receptors and s

215 owledge our study is the first to report the compartmentalization of NK cells responses during system

216 ns, mislocalized shaft-synapses, and loss of compartmentalization of NMDA receptor-mediated calcium i

217 plex engineered microfluidic systems for the compartmentalization of nucleic acid amplification react

218 y highlights the importance of mitochondrial compartmentalization of one-carbon metabolism in cancer

219 port inhibitors clearly showed that cellular compartmentalization of overexpressed FIH-1 was critical

220 e serves the same purpose as the peroxisomal compartmentalization of oxidases in eukaryotic cells.

221 In this respect, the periplasmic compartmentalization of phenylethylamine oxidase serves

222 and MMFPh at high stringency, we identified compartmentalization of phosphorylation motifs likely re

223 Our results demonstrate that compartmentalization of proliferation during early embry

224 ief overview of our current understanding of compartmentalization of proteins in the ciliary membrane

225 Compartmentalization of reactions in pico- to nanoliter

226 Subcellular compartmentalization of receptor signaling is an emergin

227 c function requires the spatial and temporal compartmentalization of RNA metabolism via transacting R

228 oxysomes into chloroplasts for the potential compartmentalization of Rubisco or other proteins.

229 Compartmentalization of screening assays in water-in-oil

230 mmunity critically depends on the functional compartmentalization of secondary lymphoid organs.

231 al impact on virus replication, there was no compartmentalization of SIV-producing cells.

232 evidence that mitochondria contribute to the compartmentalization of spontaneous Ca(2+) signals in as

233 s/ERK signaling by controlling post-synaptic compartmentalization of SynGAP1.Excitotoxicity contribut

234 pared to adult organ donors, revealing early compartmentalization of T cell differentiation and regul

235 These findings provide insight into compartmentalization of Th cell responses and C. albican

236 s essential for transition zone composition, compartmentalization of the axoneme tip, and axoneme int

237 ny studies have hallmarked the well designed compartmentalization of the cAMP-dependent protein kinas

238 ow that selective membrane anchoring and the compartmentalization of the endoplasmic reticulum (ER) m

239 Compartmentalization of the gastrointestinal (GI) tract

240 The compartmentalization of the HPLC-eluate in a segmented f

241 We propose that spatial compartmentalization of the lipid mediator sphingosine 1

242 each other, creating a potential regulatory compartmentalization of the locus.

243 Compartmentalization of the model is based on proteomic/

244 Because compartmentalization of the plasma membrane is believed

245 nuclear spacing, centrosome segregation, and compartmentalization of the syncytial embryo.

246 These locus-specific controls reveal compartmentalization of the T. brucei genome in terms of

247 ansfer processes in the cell, with different compartmentalization of the two splice variants of TUM1.

248 However, the compartmentalization of this pathway and the transport o

249 Compartmentalization of this process to rough ER membran

250 Compartmentalization of Toll-like receptors (TLRs) in in

251 ies, as well as the single-particle, spatial compartmentalization of various catalytic functions to c

252 onstructural protein 3 sequence analysis, no compartmentalization of viral populations was observed b

253 Spatial compartmentalization of, and directed molecular transpor

254 Collectively, we have provided a functional compartmentalization overview and an organizational fram

255 e of superdomains and superloops, changes in compartmentalization patterns, and changes in the distri

256 Thus, cytoplasmic compartmentalization persists during early mitosis to pr

257 Indeed, biological barriers such as physical compartmentalization, pressure gradients, and excretion

258 This immediate compartmentalization prevents peak dispersion during elu

259 Such compartmentalization processes could occur within retros

260 We conclude that electrical compartmentalization profoundly shapes both synaptic fun

261 the RQC-Hsf1 regulatory system and that such compartmentalization, rather than ubiquitination, is key

262 7BL/6J mice also show differences in PDE11A4 compartmentalization relative to BALB/cJ mice.

263 ative to time and pulmonary localization and compartmentalization remain largely unknown.

264 tines, yet how this relates to changes in GI compartmentalization remains unclear.

265 generates larger nuclei with altered nuclear compartmentalization resulting from NE expansion around

266 data to gain new insights into intracellular compartmentalization, specifically for transporters.

267 also investigate the qualitatively different compartmentalization strategies that emerge in parameter

268 beta-carboxysomes each constitute an optimal compartmentalization strategy given the properties of th

269 in these strains leads to a loss of nuclear compartmentalization suggesting that the sealing of defe

270 ase of xenophagy, pathogen sequestration and compartmentalization suppress inflammation.

271 In contrast, compartmentalization takes place at the position of the

272 are being carried out simultaneously through compartmentalization that allows for the combination of

273 After DNA dilution and compartmentalization, the transposase is removed, resolv

274 rters (ZnTs) facilitate zinc efflux and zinc compartmentalization, thereby playing a key role in mult

275 atalytic domain of PI3KC2beta and affect its compartmentalization, thereby suppressing PI3KC2beta act

276 In addition, they regulate lymphocyte compartmentalization through the secretion of chemokines

277 esults directly link modulation of dendritic compartmentalization to circuit-level encoding of motion

278 The data showed a striking compartmentalization to coronary development.

279 scription orchestrates chromatin folding and compartmentalization to direct with high precision enhan

280 To define their compartmentalization, total RNA >100 nt was extracted fr

281 the site isolation of both catalysts through compartmentalization using a core-shell micellar support

282 onte Carlo approach; (2) evaluation of viral compartmentalization, using tree-based and distance-base

283 ic layering of cristae membranes, iv) matrix compartmentalization, v) nanotunelling, and vi) donut-sh

284 anistic basis for postsynaptic stability and compartmentalization via TAOK2-Sept7 signaling, with imp

285 Virus compartmentalization was diminished in animals with simi

286 In contrast, compartmentalization was not observed between nontumorou

287 The hypothesis of ethnic compartmentalization was tested by reconstructing ancest

288 The highest concentrations of W compartmentalization were in the snail's hepatopancreas

289 ognized regulatory mechanisms, allostery and compartmentalization, which exemplify this dissociation

290 eishmania 9-1-1 subunits mediates functional compartmentalization, which has a direct impact on the r

291 of the cell has been limited by sub-cellular compartmentalization, which segregates distinct nutrient

292 This compartmentalization, which was less evident in cases of

293 ing how the reactions are influenced by this compartmentalization will help us gain an optimal unders

294 f C. albicans infection have revealed tissue compartmentalization with tailoring of immune responses

295 compatibility are overcome through membrane compartmentalization, with the optimized process requiri

296 iew, we describe how the host uses either Cu compartmentalization within innate immune cells or Cu se

297 anization by circadian clocks and by spatial compartmentalization within organelles defined by lipid

298 ceptor that regulates T cell trafficking and compartmentalization within secondary lymphoid organs.

299 with the decline in HCV RNA, suggesting HCV compartmentalization within the tumor.

300 Compartmentalization within this infrastructure provides