ライフサイエンスコーパス: compartmentalize

1 which autophagosome biogenesis is spatially compartmentalized.

2 red exceptional and their cell plan uniquely compartmentalized.

3 differentiation and regeneration of MBCs are compartmentalized.

4 han roots and carbohydrate redistribution is compartmentalized.

5 e majority of catabolic BMCs (metabolosomes) compartmentalize a common core of enzymes to metabolize

6 nked protein microstructures, permits one to compartmentalize a small population of microbes by formi

7 Finally, we apply these new insights to compartmentalize a two-enzyme pathway in the peroxisome

8 We conclude that gravin compartmentalizes a significant pool of PKA that regulat

9 vel role for a penicillin-binding-protein in compartmentalizing a bacterial organelle it itself helps

10 The compartmentalized activity functions independently of th

11 These data indicate the importance of a compartmentalized AGO2-FXR1-iso-a complex for selective

12 Metabolism in plants is compartmentalized among different tissues, cells and sub

13 FH2-DA and DCFH2 enabled the measurement and compartmentalized analysis of intra- and extracellularly

14 arallel, multigene-profiling nanoplatform to compartmentalize and analyze hundreds of single CTCs.

15 of membrane-bound scaffolding proteins that compartmentalize and negatively regulate signal transduc

16 n summary, the data presented here show that compartmentalized and active macrophage-tropic HIV-1 var

17 We show that the highly compartmentalized and cell type-specific organization de

18 In eukaryotic cells, metals are highly compartmentalized and chelated.

19 proteins to generate the wide assortment of compartmentalized and cytosolic cilia observed in nature

20 , bird-plant networks were more nested, less compartmentalized and dominated by strong interactions b

21 Extant eukaryotes are highly compartmentalized and have integrated endosymbionts as o

22 e neuromodulatory actions of NA and 5-HT are compartmentalized and regulate the input-output properti

23 f the mitotic flare indicates that the NE is compartmentalized and that there is a mechanism by which

24 Voltage-gated ion channels amplify, compartmentalize, and normalize synaptic signals receive

25 ng pathways modulated by ROS are complex and compartmentalized, and we are only beginning to identify

26 ol (PEG) and dextran (DEX) have been used to compartmentalize antibodies and prevent cross-talk in mu

27 ts for multiplex ELISA retain the ability to compartmentalize antibodies and prevent cross-talk, whil

28 In addition to their compartmentalized antiviral actions, these two systems a

29 -deficient bone marrow eosinophils underwent compartmentalized apoptosis, resulting in decreased bloo

30 erative rounds of in vitro selections within compartmentalized aqueous droplets, which enable screeni

31 The reconstructed compartmentalized Arabidopsis tissue models are MIRIAM-c

32 paratus and depend on its highly complex and compartmentalized architecture.

33 from primary cortical neurons in modular 3D compartmentalized architectures with electrophysiologica

34 The low-input material is compartmentalized as single molecules in millions of pic

35 In select cases, the basal septum appears compartmentalized as the stimulated wavefront is reroute

36 Here, we show that proliferation is compartmentalized at the posterior end of the embryo dur

37 The continuous growth of non-compartmentalized axonal processes provides a vesicle re

38 It reflects systemic and compartmentalized B cell accumulation and activation.

39 tmorillonite (K-SWy2) were established using compartmentalized batch reactors by varying the sequence

40 llular responses in vaginal tissue were more compartmentalized, being induced primarily by intravagin

41 asured z-groove index, T-tubule density, and compartmentalized beta(2)AR-mediated cAMP signals, using

42 Dephosphorylation compartmentalizes beta-catenin on PCREs, a specialized c

43 further enhances noncanonical Wnt signals by compartmentalizing beta-catenin.

44 Eukaryotic cells compartmentalize biochemical processes in different orga

45 es provide a general regulatory mechanism to compartmentalize biochemical reactions within cells.

46 Compartmentalized biochemical activities are essential t

47 We engineered compartmentalized biomimetic colorectal tumouroids with

48 odel liquid organelles capable of reversibly compartmentalizing biomolecules.

49 The fission yeast plasma membrane is highly compartmentalized by distinct sets of cortical nodes, wh

50 roughout the apical dendritic tuft is highly compartmentalized by voltage-gated potassium (KV) channe

51 Spines compartmentalize calcium, and this biochemical isolation

52 d as important regulatory molecules that can compartmentalize cAMP signaling transduced by beta2-adre

53 n and activity strongly influence global and compartmentalized cAMP levels.

54 t of PKD, possibly through the regulation of compartmentalized cAMP pools that control cell prolifera

55 patial cAMP degradation so as to orchestrate compartmentalized cAMP signaling in cells.

56 ortant implications for the understanding of compartmentalized cAMP signalling.

57 er (FRET)-based sensor, CUTie, which detects compartmentalized cAMP with unprecedented accuracy.

58 Compartmentalized cAMP/PKA signalling is now recognized

59 Poststroke tissue remodeling results in a compartmentalized cavity that can directly accept a ther

60 The maize endosperm consists of three major compartmentalized cell types: the starchy endosperm (SE)

61 questering different membrane components can compartmentalize cellular processes and regulate signali

62 These findings establish compartmentalized cellular RNA binding activity as a mec

63 athway complexity in plants and their highly compartmentalized cellular structure.

64 zed into larger domains, consequently better compartmentalizing cellular functions.

65 ssed under the plasma membrane and generates compartmentalized cGMP in gut epithelia in UC.

66 Using motor neurons cultured in compartmentalized chambers, we demonstrated that axonal

67 cooperative effects in an extended system of compartmentalized chemical oscillators under batch and s

68 coding genes are organized into functionally compartmentalized chromatin communities and undergo coor

69 cilia, also contributes to the formation of compartmentalized cilia.

70 Such compartmentalized ciliogenesis depends on the core intra

71 ely generated by evolutionary derivations of compartmentalized ciliogenesis.

72 and ClpA hexamers collaborate with the self-compartmentalized ClpP peptidase to unfold and degrade s

73 acrophage-tropic Envs in brain tissue formed compartmentalized clusters distinct from non-macrophage-

74 The spontaneous assembly of micro-compartmentalized colloidal objects capable of controlle

75 The scaffold design provides compartmentalized control for spatial separation of neur

76 s at boutons are key determinants underlying compartmentalized control of AP width in a near synapse-

77 t somatostatin-expressing interneurons exert compartmentalized control over postsynaptic Ca(2+) signa

78 We disclose compartmentalized corelease of glutamate and GABA and it

79 Using compartmentalized culture systems that isolate axons and

80 restingly, distal axon application of NGF in compartmentalized cultures of rat DRG sensory neurons wa

81 We show that in compartmentalized cultures of rat sympathetic neurons, a

82 Phosphorylation compartmentalizes Daple/beta-catenin/E-cadherin complexe

83 On a larger scale, cells use compartmentalized defenses and networks of communication

84 ssing of excitatory synaptic inputs involves compartmentalized dendritic Ca(2+) oscillations.

85 access by the surrounding Scr enhancers and compartmentalizing distinct histone modifications, and t

86 Kainate receptors exhibit a highly compartmentalized distribution within the brain; however

87 his transplant strategy consistently induced compartmentalized donor chimerism, (significant whole-bl

88 Here we show that compartmentalized Drosophila olfactory receptor neurons

89 This compartmentalized dual counterstream organization allows

90 ic cellular structures that are critical for compartmentalizing environments within tissues and regul

91 Cells routinely compartmentalize enzymes for enhanced efficiency of thei

92 their membranes to modulate the activity of compartmentalized enzymes or to convey specific cellular

93 quent secretion of APP fragments from highly compartmentalized, euploid neurons that express APP and

94 Hence, this compartmentalized examination of VH sequences may pave t

95 d action potential output was regulated in a compartmentalized fashion mainly by a G-protein-activate

96 Using simulations, we show that such a compartmentalized form of synaptic scaling has computati

97 n than to facilitated transport, revealing a compartmentalized functional arrangement within the NPC.

98 ltifunctional materials comprising spatially compartmentalized functions.

99 lex cytoskeletal environment of dendrites by compartmentalizing functions in an activity-dependent ma

100 ctural features of the gag-pol mRNA actively compartmentalize Gag to preferred sites within the cytop

101 The power density of the non-compartmentalized GBFC constructed from GC/MWCNTs/Ptb/LA

102 It controls compartmentalized gene expression, allowing the liver to

103 Compartmentalized genome-scale metabolic models construc

104 ed in Akap9 mutant testes, and Cx43 fails to compartmentalize germ cells near the BTB.

105 ttability are synthesized through a one-step compartmentalized growth of a mesoporous organosilica sp

106 d to Pteronymia diversification by providing compartmentalized habitats and an array of biotic and ab

107 Yet, how this structure is compartmentalized has not been clearly elucidated.

108 r pathogens are differentially sensed by the compartmentalized host immune system.

109 ammalian tissues are often heterogeneous and compartmentalized; however, whether distinct niche locat

110 E.g., in the highly compartmentalized human body, drug levels can vary subst

111 nimmunologic diseases, and the importance of compartmentalized immune responses.

112 rogrammed pores"--multiple functional groups compartmentalized in a predetermined array within a peri

113 te and GABA, as well as their plasticity are compartmentalized in a target-dependent manner, showing

114 r, our data indicate that the ER membrane is compartmentalized in cells as diverse as budding yeast,

115 tein expression is dynamically regulated and compartmentalized in developing neurons.

116 tation of the potential of protein libraries compartmentalized in droplets in a straightforward proto

117 Due to the small amounts of compound compartmentalized in each droplet, detection has been pr

118 Experiments with clusters of tumor cells compartmentalized in microfluidic drops reveal that cell

119 ion through the function of HSP90 chaperones compartmentalized in mitochondria.

120 ude that critical substrate-enzyme pairs are compartmentalized in neutrophils and platelets during st

121 r, these data suggest that cAMP pathways are compartmentalized in sperm, with Gs and tmAC in the head

122 In vertebrates, S1P is spatially compartmentalized in the blood and lymphatic circulation

123 he functions of which are characteristically compartmentalized in the cells.

124 n plants proceeds through two major pathways compartmentalized in the chloroplast and the endoplasmic

125 ansporters, chaperone-bound S1P is spatially compartmentalized in the circulatory system.

126 Compartmentalized in the droplets, analytes reacted with

127 imer-functionalized microbeads, are randomly compartmentalized in the droplets.

128 The gut microbiota is compartmentalized in the intestinal lumen and induces lo

129 ator of sigma(F), the phosphatase SpoIIE, is compartmentalized in the small cell by transfer from the

130 necessary for associative information to be compartmentalized in this way, but the mechanism by whic

131 eening, in which members of enzyme libraries compartmentalized in water-in-oil emulsion droplets are

132 sition cells along the crypt-villus axis and compartmentalize incipient colorectal tumors.

133 roughput approach that uses microfluidics to compartmentalize individual cells for growth and analysi

134 iation, TBM-IRIS was associated with severe, compartmentalized inflammation in the CSF, with elevated

135 + gammadelta T cells might contribute to the compartmentalized inflammatory process in the central ne

136 dynamic interactions between components of a compartmentalized inflammatory response.

137 orikoshii (PhAAP), revealing a complex, self-compartmentalized inner space, where substrates may acce

138 The protein samples are compartmentalized inside droplets, each one acting as an

139 cells, we show that free and bound NADH are compartmentalized inside of the nucleus, and its subnucl

140 that can modulate GlyT2 activity based on a compartmentalized interaction between GlyT2, neuronal pl

141 , affording nanometer-sized particles with a compartmentalized interior.

142 e morphogenesis of the early endoderm into a compartmentalized intestinal epithelium comprised of vil

143 are rapidly uptaken by the cells and become compartmentalized into different cellular regions.

144 ey are necessary for striatal learning to be compartmentalized into different states as the state of

145 t receptor tyrosine kinases are functionally compartmentalized into distinct collaborative groups dis

146 Eukaryotic plasma membranes are compartmentalized into functional lateral domains, inclu

147 rescence anisotropy measurements of reagents compartmentalized into individual nanoliter droplets are

148 ally differentiate or if these functions are compartmentalized into MBC subsets has remained unclear.

149 ADAM10 is compartmentalized into membrane microdomains formed by t

150 le transcriptional oscillator system that is compartmentalized into microemulsion droplets with volum

151 micro T-junction, where the eluate stream is compartmentalized into picoliter droplets.

152 es have revealed that the Fusarium genome is compartmentalized into regions responsible for primary m

153 cing techniques are used or if templates are compartmentalized into single copies prior to amplificat

154 argeting signal peptides, the TaFAR could be compartmentalized into the matrix of the peroxisome to h

155 Our results demonstrate that compartmentalized intraciliary Ca(2+) signaling can regu

156 Highly compartmentalized intraflagellar Ca(2+) elevations initi

157 The photorespiratory pathway is highly compartmentalized, involving the chloroplast, peroxisome

158 sought to clarify the functions of these two compartmentalized isoforms.

159 lesterol-enriched membrane microdomains that compartmentalize its activated receptor and initiate its

160 y will ultimately displace TANGO1/cTAGE5 and compartmentalize its operation to the base of the growin

161 such as A-kinase anchoring proteins (AKAPs), compartmentalize kinase activity and ensure substrate se

162 ] ([Ca(2+)]i) or [H(+)] ([H(+)]i) can become compartmentalized, leading potentially to complex spatia

163 the blood and genital tract of five men with compartmentalized lineages was determined.

164 LDs compartmentalize lipids and may help to prevent cellular

165 r serious.IMPORTANCE The detection of highly compartmentalized macrophage-tropic R5 Envs in the brain

166 mical analysis revealed that MSCs were found compartmentalized mainly within vasculature structures l

167 CFTR channel function is regulated in a compartmentalized manner through the formation of CFTR-c

168 Living cells compartmentalize materials and enzymatic reactions to in

169 We developed a compartmentalized, mechanistic model to elucidate the ki

170 intracellular stores in mediating spatially compartmentalized memory of the activity history of a ne

171 A sequential extraction technique for compartmentalizing mercury (Hg) in leaves was developed

172 validation of irreversibility constraints in compartmentalized metabolic models, at the same time pro

173 s and the products from these substrates are compartmentalized metabolically.

174 Our results showing compartmentalized metabolism of cyanophycin identify the

175 The compartmentalized microchannels separated by the porous

176 Here we used compartmentalized microfluidic chambers to characterize

177 Neuronal cultures in compartmentalized microfluidic-chambers demonstrate that

178 ntifying unique features of the anatomically compartmentalized milk SIV populations could enhance our

179 ycosomes of trypanosomes, which have come to compartmentalize most of the glycolytic pathway and play

180 egregants from RNAi suppression lines to sub-compartmentalize MSH1 effects.

181 Our studies reveal compartmentalized mucosal immune responses within the na

182 enzymes; however, the challenge in measuring compartmentalized NAD(+) in cells has precluded direct e

183 same genomic regions (P < 0.05), revealing a compartmentalized network structure that may reflect net

184 two methods to quantitate ADS events using a compartmentalized neuronal culture system.

185 Using compartmentalized neuronal cultures, we further demonstr

186 Eukaryotic cells compartmentalize neutral lipids into organelles called l

187 at in LPS-challenged CF MPhis, HO-1 does not compartmentalize normally to the cell surface and instea

188 synaptic contacts from each nerve are often compartmentalized onto dendrite segments of convergently

189 n of apoptotic cells can therefore spatially compartmentalize or prevent premature or ectopic activit

190 led that peroxisome could be engineered as a compartmentalized organelle for producing fatty acid-der

191 keratinocytes (KCs) is a complex and highly compartmentalized organelle, whose structure is markedly

192 icroRNAs have also been detected in membrane-compartmentalized organelles, but the functional signifi

193 R) is an organelle that maintains a complex, compartmentalized organization of interconnected cistern

194 d PEX5 or PEX11 but at the same time a clear compartmentalized organization.

195 e produced by the effective environment of a compartmentalized oscillator as the cause of the lifetim

196 an approach to enhance photosynthesis or to compartmentalize other biochemical reactions to confer n

197 e organelles that catabolize fatty acids and compartmentalize other oxidative metabolic processes in

198 Compartmentalized partnered replication (CPR) is an emul

199 To overcome these barriers, here we present compartmentalized partnered replication (CPR).

200 tes, the soma, or midaxon, consistent with a compartmentalized pathway for constitutive autophagy in

201 exchange of isoprenoid intermediates between compartmentalized pathways, was assessed by a combinatio

202 However, the functional role of specific compartmentalized PDE4 isoforms has not been examined in

203 machine consists of HslV, a double-ring self-compartmentalized peptidase, and one or two AAA+ HslU ri

204 ain behaviors, but will not map clearly into compartmentalized pieces of the brain, could represent a

205 ain behaviors, but will not map cleanly into compartmentalized pieces of the brain.

206 erved kinase-activation loop through GTP-Rac compartmentalized PKA activities.

207 This will test our hypothesis that compartmentalized PKD signaling reconciles disparate fin

208 rganic framework materials on the surface of compartmentalized polymer microparticles is achieved by

209 cal separation, whereby different subsurface compartmentalized pools of water supply either plant tra

210 Alterations of compartmentalized PPIs emanating from certain deregulate

211 the nuclear piston migration mechanism with compartmentalized pressure characteristic of nonmalignan

212 Achieving compartmentalized pressure required the nucleoskeleton-c

213 larized HT1080 and SW684 cells and generated compartmentalized pressure.

214 Although photorespiration is a compartmentalized process with enzymatic reactions in th

215 Metabolism is a compartmentalized process, and it is apparent in studyin

216 As the field matures, there is a need to compartmentalize processes in different spatial localiti

217 sought to determine how stress alters these compartmentalized processes.

218 tical neuron has been optimized for layered, compartmentalized processing under in-vivo-like spiking

219 re also found in thin dendrites which act as compartmentalized processing units and generate local ca

220 archaeal proteasomes are paradigms for self-compartmentalizing proteases.

221 distinct from those of known bacterial self-compartmentalizing proteases.

222 Bacteria have various types of self-compartmentalizing proteases; in addition to the proteas

223 nd their interactions enabling an extensive, compartmentalized protein-protein interaction network an

224 ting the ability of this approach to resolve compartmentalized reactions in intact cells.

225 By tracing hydrogen in compartmentalized reactions that use NADPH as a cofactor

226 ization of D2R was largely restricted to the compartmentalized receptor.

227 RET reporter sensors have helped define more compartmentalized regulation of cAMP, PKA, and EPAC, the

228 diated inhibition, with implications for the compartmentalized regulation of dendritic signaling in t

229 cational insertion, in which MPs function to compartmentalize replication complexes at PD for localiz

230 As such, neuronal signaling is highly compartmentalized, requiring sophisticated transfer mech

231 after the resolution of infection, including compartmentalized responses against epitopes within all

232 gh mediating RGS subcellular localization to compartmentalize RGS activity within a cell, thus highli

233 he function of MEcPP from SA, and expose the compartmentalized role of this retrograde signaling meta

234 y-induced supramolecular interactions yields compartmentalized SCPNs comprised of distinct microdomai

235 By compartmentalizing SCs into micro-niches, tissues gain p

236 ation of plasma membrane receptors initiates compartmentalized second messenger signaling.

237 ous throughout the cell, but its membrane is compartmentalized shortly before nuclear envelope breakd

238 tein kinase A (PKA) is the prime example for compartmentalized signal transmission downstream of dist

239 Compartmentalized signaling in dendritic subdomains is c

240 that regulate cardiomyocyte function through compartmentalized signaling in discrete subcellular micr

241 Here, we survey different modes of compartmentalized signaling in neurons, highlighting exa

242 ently to odors, revealing their capacity for compartmentalized signaling in vivo.

243 ium is a paradigmatic organelle for studying compartmentalized signaling; however, unlike soluble pro

244 MP-sensing Gpr161:PKA complex acts as cilium-compartmentalized signalosome, a concept that now needs

245 These compartmentalized single-chain objects were prepared by

246 ibodies are detected after only 15 min by co-compartmentalizing single mouse hybridoma cells, a fluor

247 y to their infants, and exhibit anatomically compartmentalized SIV populations in milk and plasma.

248 onically SIV-infected AGMs have anatomically compartmentalized SIV variants in plasma and milk, where

249 ey feature of the platform is the ability to compartmentalize small populations of adherent and nonad

250 uggest that the thymidine salvage pathway is compartmentalized so that TMP kinase prefers TMP synthes

251 interior of the eukaryotic cell is a highly compartmentalized space containing both membrane-bound o

252 ing of the actin cytoskeleton in this highly compartmentalized space, but the precise mechanisms rema

253 This is supported by the compartmentalized spatial profile of calcium elevations

254 ained by patterned transcription factors and compartmentalized stem cell progeny.

255 ational principles that underlie assembly of compartmentalized structures at the plasma membrane.

256 Eukaryotic plasma membranes are highly compartmentalized structures.

257 plication within the tumor is restricted and compartmentalized, suggesting segregation of specific vi

258 nd L5 dorsal root ganglia were cultured in a compartmentalized system.

259 ng of the role of compartments and designing compartmentalized systems needs reliable modelling/syste

260 offer vital clues on the behavior of simple compartmentalized systems, such as prebiotic precursors

261 antioxidant loss was more pronounced in more compartmentalized systems, which was attributed to their

262 selectively activate TGN-associated arms of compartmentalized TCR signaling.

263 g ameloblasts or the root epithelial lineage compartmentalizes teeth into crowns and roots.

264 we show that one of these enzymes is a self-compartmentalizing tetrameric aminopeptidase with a pref

265 ind that developmental domains are less well compartmentalized than constitutive domains and display

266 , and FtsZ is required but not sufficient to compartmentalize the cytoplasmic membrane at the divisio

267 Carboxysomes compartmentalize the enzyme ribulose-1,5-bisphosphate ca

268 inuously migrates away from the centriole to compartmentalize the growing axoneme tip.

269 In the first step we compartmentalize the individual RNA molecules (based on

270 Thus, betaII spectrin serves to compartmentalize the membrane of myelinated axons at spe

271 ndages and/or at the cleavage furrow to help compartmentalize the plasma membrane and support cytokin

272 many cell types, lateral diffusion barriers compartmentalize the plasma membrane and, at least in bu

273 of a static interaction with the axoneme to compartmentalize the site of axoneme assembly.

274 -reorganizing properties of TGB1 function to compartmentalize the viral gene products of PVX infectio

275 Patterns of co-mutation compartmentalized the cohort into 11 classes, each with

276 Multiple forms of synaptic inhibition compartmentalized the GAC dendritic tree and endowed all

277 nucleus can act as a piston that physically compartmentalizes the cytoplasm and increases the hydros

278 ability to capture luminal bacteria, thereby compartmentalizing the intestinal immune response to avo

279 Compartmentalizing the network structure into interconne

280 ed by the cell to sequester biomolecules and compartmentalize their function.

281 signaling molecules and in coordinating and compartmentalizing their activity.

282 a tunable regulator of neurogenesis via its compartmentalized thiol-oxidative function.

283 nal pipeline for the reconstruction of fully compartmentalized tissue-specific models of Arabidopsis

284 For this purpose, the reaction is first compartmentalized to a train of many identical plugs.

285 est that distinct progenitor populations are compartmentalized to discrete axial domains in the early

286 vant given alone and were almost exclusively compartmentalized to the lung.

287 ma-carboxylation in the ER and therefore was compartmentalized to the Trans-Golgi Network (TGN) and a

288 rstitial connective tissue, which ultimately compartmentalizes tongue muscles and serves as their att

289 entially conserved communication between the compartmentalized two-sector rotary ATPases.

290 ages have evolved a specialized structure to compartmentalize viral replication.

291 e nucleus and assemble highly structured and compartmentalized viral genome domains.

292 Pyramidal neuron (PN) dendrites compartmentalize voltage signals and can generate local

293 transmission, and the extent to which spines compartmentalize voltage, specifically excitatory postsy

294 the intracellular NR pools are likely to be compartmentalized, which contributes to the regulation o

295 ophes affecting a single, laggard chromosome compartmentalized within a micronucleus.

296 It is widely accepted that cAMP signaling is compartmentalized within cells.

297 rent realization that biogenic processes are compartmentalized within organelles and bacteria.

298 tiple cross-sectional studies suggest HIV is compartmentalized within the female genital tract.

299 DNA is strictly compartmentalized within the nucleus to prevent autoimmu

300 The nucleus is highly compartmentalized yet dynamic.