ライフサイエンスコーパス: compensatory

1 es are graded, age and tissue dependent, and compensatory.

2 F, the PD on medication group showed reduced compensatory activation in the putamen.

3 expression remained high, likely because of compensatory activation of hepcidin by mild inflammation

4 hypertensive patients, leading to a loss in compensatory activity during neurogenic hypertension.

5 DGAT1-silencing lines are likely due to the compensatory activity of a TAG-synthesizing enzyme with

6 This effect probably works as an attentional compensatory activity used to compensate for the degrade

7 Without compensatory activity, such abnormalities could potentia

8 n coupling in health as well as hypertrophic compensatory adaptation and represent a structural and m

9 ic transcriptional suppression and long-term compensatory adaptation by sex-linked genes.

10 This transmissible compensatory adaptation relied on environmental factors,

11 This may be due in part to compensatory adaptations, in which calories expended dur

12 propriate levels of spiking activity through compensatory adjustments in the strength of synaptic inp

13 and immunocytochemistry revealed that these compensatory alterations were associated with a distal s

14 In the cerebellum, both compensatory and detrimental contributions seem to occur

15 rtical input after stroke, thus allowing for compensatory and independent action of these circuits.

16 cantly higher in exposed oysters, suggesting compensatory and physical effects on both digestive para

17 Thus, derived alleles may be compensatory and restore interactions altered as a conse

18 These changes outweigh the compensatory antikaliuretic effects of diminished ROMK e

19 alvanic vestibular stimulation, indicating a compensatory arm response to a sensation of altered body

20 ear stress (WSS) dependent leukocyte TEM and compensatory arterial remodeling obeying Glagov's phenom

21 ual's optimal asynchrony and then applying a compensatory auditory delay.

22 Importantly, a compensatory augmentation in insulin secretion occurs fo

23 between PTSD and weight gain resulting from compensatory behaviors (vomiting, laxative use, fasting,

24 We found that compensatory behaviors in one-handers involved multiple

25 However, the repertoire of compensatory behaviors may involve utilization of other

26 associated with starvation is accompanied by compensatory behaviours that enhance foraging efficiency

27 pression in beta-cells is sufficient for the compensatory beta-cell differentiation.

28 , does not provoke overt diabetes as long as compensatory beta-cell function is maintained.

29 a-cell-specific FoxM1 deficiency also blocks compensatory beta-cell proliferation.

30 show the molecular mechanism underlying this compensatory beta-cell proliferation.

31 summary, PKCzeta activation is key for early compensatory beta-cell replication in insulin resistance

32 uption of PKCzeta in mouse beta-cells blocks compensatory beta-cell replication when acute hyperglyce

33 ergic medications to determine whether these compensatory brain changes are altered with dopamine.

34 t to run out of Ca(2+) , there is a need for compensatory Ca(2+) uptake from the extracellular fluid.

35 d cognitive health in ageing, and to enhance compensatory capacity for synaptic connectivity in patho

36 ing of synaptic transmission, expressed as a compensatory change in quantal size following chronic ac

37 ver from Mpc1 hypomorphic embryos identified compensatory changes in amino acid and lipid metabolism.

38 in calcium influx, and translates this into compensatory changes in excitatory quantal amplitude.

39 These compensatory changes in functional brain activity were p

40 nstem, and hypothalamus, possibly reflecting compensatory changes in serotonergic innervation precedi

41 Compensatory changes in SPAK/OSR1-independent phosphoryl

42 n in the hBCRP mice and the absence of major compensatory changes in the expression of other genes in

43 mmatory cell recruitment was associated with compensatory changes in the expression profiles of CCL2,

44 of morphogenic scaling that have focused on compensatory changes in the morphogen gradient itself.

45 in iput1 mutants is complicated by the vast compensatory changes in the sphingolipidome; however, ou

46 These data demonstrate unexpected and compensatory changes involving the TM in the NHP model o

47 lts of the present study indicate that early compensatory changes may be taking place within the neur

48 es have aimed at differentiating the initial compensatory changes that occur within the heart with ag

49 This insensitivity derives from compensatory changes to the pattern of local and long-ra

50 The outcomes reveal the compensatory character of some phenomena and explain the

51 event increases chloride efflux, leading to compensatory chloride influx via NCC activation at the c

52 f self-position/orientation in space, and to compensatory circuits including the vestibulo-ocular and

53 cis-acting, trans-acting and, surprisingly, compensatory cis-trans effects.

54 re removed and the affected eyes fitted with compensatory contact lenses (mean duration of deprivatio

55 ical regulation of coupling conductance in a compensatory context, and of synergistic plasticity acro

56 Our results demonstrate that the observed compensatory covariation of amino acids in eukaryotic lo

57 Different life-history traits and compensatory demographic mechanisms between the three sp

58 e found no evidence in any of the groups for compensatory directional response towards their expected

59 dministered loop diuretics develop DR due to compensatory distal tubular sodium reabsorption, but whe

60 nucleolytic activity is required to activate compensatory DNA synthesis during mitosis and to resolve

61 rtional to whole-body fat mass, suggesting a compensatory down-regulation, presumably to prevent exce

62 sistent with increased iron accumulation and compensatory downregulation of uptake pathways.

63 ecies, stability of subordinate species, and compensatory dynamics among species strongly influenced

64 We find that compensatory dynamics lead to trajectories of sediment m

65 in rapid changes in appetite that result in compensatory eating, which may initially dissuade potent

66 complex; they provide an explanation for the compensatory effect of BMP6 treatment on the molecular d

67 other LanCL proteins (LanCL2/3) may confer a compensatory effect, triple knock-out (TKO) mice were al

68 These compensatory effects influence expression in opposite di

69 The suppressor phenotype was not caused by compensatory effects of additional chloroplast antioxida

70 eased cerebellar connectivity in HD may have compensatory effects on behavioral performance.

71 nsitivity is attributable, in part, to their compensatory effects on C uptake, whereby comparable est

72 ent, like primates and Muridae, illustrating compensatory emergences of new MH1Like/Invariant T-cell

73 low endocytosis, but also for rapid phase of compensatory endocytosis.

74 fraction of them escaped PI3K dependence by compensatory ERK activation, which can be blocked by com

75 xhibited microcytic anemia and activation of compensatory erythropoiesis via the regulators erythropo

76 thenolide regimen as a means to inhibit such compensatory events and thereby further enhance eradicat

77 en these genes and genes showing evidence of compensatory evolution, consistent with the idea that re

78 ocesses including epistatic interactions and compensatory evolution, coselection of drug resistances,

79 Loss of PKM2 leads to compensatory expression of PKM1 in the tissues that norm

80 information and is important for generating compensatory eye movements.

81 Strikingly, a compensatory FANCA somatic mutation from an "experiment

82 tiplicatively scaled upward or downward in a compensatory fashion.

83 ed by its comparatively stable C:N ratio and compensatory feeding on N-limited prey.

84 The compensatory force patterns were largely based on the pe

85 to determine whether PD participants engage compensatory frontostriatal mechanisms during working me

86 osely related GalNAc-T3 homolog did not show compensatory functionality for effects observed for GalN

87 ectively lowers blood glucose but results in compensatory glucagon hypersecretion involving expansion

88 tissues for acclimation and by facilitating compensatory growth following drought.

89 erythropoiesis, chronic haemolytic anaemia, compensatory haemopoietic expansion, hypercoagulability,

90 asal renal function but markedly compromised compensatory hemodynamic responses to hemorrhage.

91 ctomy of the adult mammalian liver activates compensatory hepatocyte hypertrophy and cell division ac

92 hibit diminished p53 activation and elevated compensatory hepatocyte proliferation, resulting in incr

93 cinogenesis by inhibiting carcinogen-induced compensatory hepatocyte proliferation, thus limiting the

94 ree of functional redundancy, and that their compensatory herbivory may play an important role in eco

95 quasi-normal bone mineral phenotype through compensatory homeostatic mechanisms involving Cyp24a1 We

96 oes not link glucagon receptor inhibition to compensatory hyperglucagonemia or expansion of alpha-cel

97 n early thymic T cell progenitors results in compensatory hyperproliferation of immature thymocytes a

98 this pathway can facilitate the promotion of compensatory hypertrophic growth.

99 Renal compensatory hypertrophy (RCH) restores normal kidney fu

100 These data provide direct evidence for the compensatory hypothesis and add novel insight into the e

101 e, the Distancing-Embracing model appeals to compensatory ideas in explaining the appeal of artworks

102 g influenza virus infection because of other compensatory immune mechanisms.

103 Conversely, hypermetabolism is likely compensatory in regions where it is associated with decr

104 in resistance and/or overnutrition induces a compensatory increase in beta-cell mass.

105 N neurons optogenetically quickly triggers a compensatory increase in carotid body activity.

106 uced obesity and insulin resistance due to a compensatory increase in energy expenditure.

107 -stage clinical development, elicit a robust compensatory increase in ER-dependent transcription that

108 mpairs glucose oxidation, which results in a compensatory increase in fatty acid oxidation and glycol

109 red whether associations varied according to compensatory increase in heart rate.

110 These defects are associated with a compensatory increase in oxidative phosphorylation per m

111 Shortest LOS hospitals did not exhibit a compensatory increase in payments for postdischarge care

112 many features of CKD, in association with a compensatory increase in the mitochondrial ATP pool via

113 g the use of one antibiotic often requires a compensatory increase in the use of other antibiotics, w

114 We found a compensatory increase in transporter expression in neuro

115 n in central auditory pathways, resulting in compensatory increased activation in the cognitive contr

116 we identified a requirement for CDK2 in the compensatory increases in beta-cell mass that occur in r

117 ts in rodents are commonly studied models of compensatory increases in both insulin secretion and bet

118 Despite compensatory increases in net primary production, greate

119 emale Ppargc1a(f/+)Alb-cre(+/0) mice; while, compensatory increases in PPARG coactivator 1beta could

120 There were compensatory increases in tear production but higher tea

121 to guide experimentation, we determined that compensatory increases of both GA and electrical couplin

122 enetoclax, anti-tumor efficacy is limited by compensatory induction of MCL-1.

123 lethal, completely prevented disease through compensatory inhibition of hepatic LDL production.

124 r data suggest that VISTA represents another compensatory inhibitory pathway in prostate tumors after

125 ensitivity and subsequently by an inadequate compensatory insulin response.

126 an outward-facing (OF) conformation through compensatory intracellular salt bridge formation, which

127 hemisphere, contralateral to the PA-induced, compensatory leftward shift in pointing movements.

128 Timely initiation of compensatory liver regeneration after APAP hepatotoxicit

129 These findings support plastic, compensatory, long-term changes in activity in the audit

130 hat cortical overtake can occur instead in a compensatory manner in people born with one hand, for mu

131 The late breakage of the compensatory mechanism at work in the wall deposition pr

132 sm driving X inactivation (SAXI) [6-8] and a compensatory mechanism based on meiotic sex chromosome i

133 in older individuals, which may represent a compensatory mechanism due to a loss of canonical clock

134 reorganization of the cerebral networks as a compensatory mechanism for cognitive decrements.

135 These changes may represent a compensatory mechanism for loss of motor control as a co

136 c change, which may constitute a part of the compensatory mechanism in response to the absence of pos

137 vity was observed, which possibly acted as a compensatory mechanism in the face of the elevated endog

138 apoptosis in B cells and CMPs and induced a compensatory mechanism in which HSCs displayed enhanced

139 data, which is indicative of a synaptogenic compensatory mechanism of the abducens internuclear path

140 ize WD in male Ccr2(-/-) mice and identify a compensatory mechanism of WD that is facilitated primari

141 the GUCY2C paracrine hormone axis as a novel compensatory mechanism opposing RIGS, and they highlight

142 ighlights the complexity and importance of a compensatory mechanism that evolved in terrestrial anima

143 findings argue against a central brain motor-compensatory mechanism that generalizes across tasks.

144 ment of theta-slow gamma coupling reflects a compensatory mechanism to maintain spatial working memor

145 fect embryo transport, possibly because of a compensatory mechanism via intact CTNNB1 in the adjacent

146 us circuitry observed after stress reflect a compensatory mechanism whereby the brain drives neural s

147 linergic motor neuron synapses, indicating a compensatory mechanism within the recurrent inhibitory f

148 become more sensitive to Ca(2+) influx as a compensatory mechanism.

149 pitulates thin filament myopathy, revealed a compensatory mechanism; the lower force generation that

150 We hypothesized that compensatory mechanisms accounted for the lack of increa

151 cling - to determine whether post-extinction compensatory mechanisms alter biodiversity-ecosystem fun

152 Induction of compensatory mechanisms and ERK reactivation has limited

153 minergic neurotransmission in both the early compensatory mechanisms and the functional recovery mech

154 The data suggest that compensatory mechanisms exist in normal animals and resp

155 in driving motoneuronal firing and evidenced compensatory mechanisms following the ATD lesion.

156 dysregulated RhoA or Rac1, and they predict compensatory mechanisms for biochemical stability.

157 s mutants indicate the presence of effective compensatory mechanisms for the complex networks of mito

158 Identifying cognitive compensatory mechanisms in PD is important for understan

159 s over a wide stimulus contrast range due to compensatory mechanisms in the diverse population of pre

160 tration-resistant prostate cancer (CRPC) via compensatory mechanisms including resurgence of AR and A

161 model to further elucidate the nature of the compensatory mechanisms involved in the preclinical peri

162 Importantly, this conversion induces compensatory mechanisms involving the reactivation of en

163 a partial dopaminergic lesion is not due to compensatory mechanisms maintaining the activity of both

164 onventional knock-out animal models in which compensatory mechanisms may occur.

165 onventional knock-out animal models in which compensatory mechanisms may occur.

166 udies demonstrated the existence of powerful compensatory mechanisms of LCR regulation via a complex

167 Additionally, compensatory mechanisms often limit the ability of knock

168 veal a role for the GUCY2C paracrine axis in compensatory mechanisms opposing RIGS.

169 ment with parthenolide leads to induction of compensatory mechanisms that include up-regulated NADPH

170 ental correlates and consequences, including compensatory mechanisms that increase intrinsic excitabi

171 ty in DBN deficient mice may indicate robust compensatory mechanisms that safeguard cytoskeleton dyna

172 metabolic reprogramming, possibly requiring compensatory mechanisms to sustain the normal biosynthet

173 regulation in the rat brain, possibly due to compensatory mechanisms, imply that ZSCAN21 is not a mas

174 These results suggest engagement of compensatory mechanisms, which initially may enhance the

175 s in these behaviors and identified possible compensatory mechanisms.

176 ing the CRISPR/Cas9 technique to investigate compensatory mechanisms.

177 ce of the role of the serotonergic system in compensatory mechanisms.

178 obal cell stress response with activation of compensatory mechanisms.

179 ination units may reflect pathophysiology or compensatory mechanisms.

180 networks, suggesting both neural reserve and compensatory mechanisms.

181 quency PDs may reflect inadequacies in brain compensatory mechanisms.

182 tuents such as glycogen that are involved in compensatory metabolic mechanisms) can be observed in ta

183 There were no compensatory mitochondrial biogenesis (no induction of n

184 tion, while chronic manipulations can reveal compensatory modes of plasticity that restore behavior.

185 eactive actions, leading to quick fixes and 'compensatory modes'); (2) a configuration with an intera

186 re a viable level of enzymatic activity by a compensatory molecular mechanism.

187 A mutant in BHK cells produced a second-site compensatory mutant (V231I) that partially rescued both

188 heless, replicative fitness is restored by a compensatory mutation that restores particle stability.

189 body stability and to what extent additional compensatory mutations are required to maintain stabilit

190 Compensatory mutations in regulatory loci controlling ex

191 e mutations in bothparCandgyrA, and putative compensatory mutations inuraAorIMPDHunder drug selection

192 abilizing process and that co-enrichment for compensatory mutations is critical for maintaining therm

193 68 (66%) of 103 clustered MDR strains had compensatory mutations of rifampicin resistance.

194 The location of the compensatory mutations restoring fusion activity strongl

195 ein concentrations above wild-type levels or compensatory mutations within gene D suppressed faulty e

196 5% for primary mutations and 10.5%-99.9% for compensatory mutations).

197 ccipital alpha-band effects are in line with compensatory neural mechanisms such as increased cogniti

198 edication-free patients likely represented a compensatory, neuroplastic response that attenuated symp

199 ger signaling cascades mediating potentially compensatory neuroprotection against excitotoxic insult.

200 ctively, our results identify a paradigm for compensatory neuroprotective PK2 signalling in nigral do

201 d mice with Th cell impairment experienced a compensatory neutrophil response that required IL-17A.

202 result of land use practices, yet there are compensatory opportunities to enhance productivity and S

203 ivation, progression to SCC required loss of compensatory p21 expression.

204 ues associated with central regulators using compensatory payments as a means of resolving jurisdicti

205 We find that compensatory payments from Pennsylvania Act 13, which ar

206 Insects respond by compensatory physiological and morphological changes in

207 The benefits of this compensatory plasticity are limited, as the recovery of

208 d cochlear denervation due to a progressive, compensatory plasticity at higher stages of the central

209 et-dependent manner, showing counterbalanced compensatory plasticity of two neurotransmitters release

210 cate that ascending sensory input guides the compensatory plasticity that normally prevents the plast

211 explore the mechanisms responsible for this compensatory plasticity, we transected the spinal dorsal

212 eir key features are preserved by additional compensatory plasticity.

213 rey but also domesticated them, leading to a compensatory population expansion of dogs.

214 may be interpreted to reflect a differential compensatory potential of distinct language networks.

215 interaction between Parkin and SLP-2 and the compensatory potential of SLP-2 suggest a functional epi

216 mental effort in older adults, and that the compensatory processes accompanying frontal hyperactivat

217 equestration because of diversity change and compensatory processes at the community scale ameliorate

218 ociated with altered PNS regulation and that compensatory processes linked to frontal overactivation

219 Alzheimer's disease (AD), via frontal compensatory processes, may affect PNS regulation, there

220 tterns among brain areas, perhaps reflecting compensatory processes.SIGNIFICANCE STATEMENT Parkinson'

221 e auditory signal is degraded, but that this compensatory processing has behavioral consequences: eve

222 This diversified compensatory profile was associated with large-scale cor

223 time, suggesting that a lack of IL-6 led to compensatory proinflammatory effects by other cytokines,

224 o DEN-induced injury was sufficient to block compensatory proliferation and annihilate development of

225 pendently, directed hepatic fibrosis and the compensatory proliferation of hepatocytes and biliary ce

226 ndent RIPK1 phosphorylation in LPCs inhibits compensatory proliferation of hepatocytes and intrahepat

227 ORC1 by rapamycin effectively attenuates the compensatory proliferation of hepatocytes in CAMK2gamma(

228 Apoptosis has been implicated in compensatory proliferation signaling (CPS), whereby dyin

229 esis by inhibiting EGFR-dependent hepatocyte compensatory proliferation.

230 tributes to therapeutic resistance through a compensatory prosurvival signaling mechanism.

231 most severely disrupted in autophagy and in compensatory proteostasis pathways.

232 Through selective host RNA depletion and compensatory protocol adjustments for ultra-low RNA inpu

233 Because the same body parts used for compensatory purposes are those showing increased repres

234 ity of the sympathetic nervous system may be compensatory, rather than purely pathological, mechanism

235 produce acute short-term effects to improve compensatory reactions and gait stability.

236 This shift is often described as a compensatory recruitment of prefrontal regions due to ag

237 This combination of slow life history and compensatory recruitment promotes the persistence of a n

238 within minutes, as well as a decrease in the compensatory reflex response that lasted up to 8 hours.

239 for both quick voluntary maneuvers and slow compensatory reflexes using only a dozen pairs of muscle

240 The compensatory regulation within the bacitracin network ca

241 al that one reason for that tolerance is the compensatory relationship between centrosomes and the SA

242 Taken together, our findings implicate compensatory release of IL10 as one of the adaptive resi

243 uA1 in morphine-dependent rats, suggesting a compensatory removal of AMPARs from synaptic zones.

244 itor populations is crucial not only for the compensatory replenishment of granule neurons but also f

245 increased blood mitochondrial abundance is a compensatory response and attenuates the cardiac effects

246 The intracellular mediators of this compensatory response are poorly defined and their ident

247 creasing M1 inhibitory tone is an endogenous compensatory response designed to limit dyskinesia sever

248 The inability to sustain a vascular compensatory response limits glucose-mediated increases

249 induction of Mg29 in the failing heart is a compensatory response that directly counteracts the well

250 However, it is not known if cells mount a compensatory response to counter this potentially delete

251 on of ER Ca(2+) homeostasis in the beta-cell compensatory response to diet-induced obesity.

252 ibition in glioma cells results from a rapid compensatory response to EGFR inhibition that mediates c

253 changes in arm trajectory consistent with a compensatory response to maintain upper-limb accuracy in

254 We recently discovered that induction of a compensatory response to repair the defective barrier is

255 es increased oxidative capacity and may be a compensatory response to the stressors that this project

256 beta-cells in fgf1(-/-) animals rescued the compensatory response, indicating that beta-cells can be

257 LysoPC restriction induces a compensatory response, linking parasite metabolism to th

258 contrast, the patients produced even larger compensatory responses than controls, suggesting an incr

259 Strengthening the compensatory responses through the use of balance pertur

260 r ablation of renal nerves adversely affects compensatory responses to hemodynamic challenge has not

261 ts suggests that it does not underlie slower compensatory responses to horizontal motion but rather c

262 mited in some circumstances by HIF-dependent compensatory responses to increased intratumoral hypoxia

263 These findings were interpreted as compensatory responses to lower GABA levels in ChCs.

264 d survival in a widespread tundra plant show compensatory responses to warming throughout the species

265 n activity showed features consistent with a compensatory role including: peaking between 60 and 100

266 s in cognitive function, suggests a putative compensatory role of hyperintrinsic connectivity in the

267 beta-adrenergic stimulation it could play a compensatory role that may mitigate some adverse effects

268 ese data demonstrate a critical, and perhaps compensatory, role of Sox10 and BRG1 in oligodendrocytes

269 Compensatory roles for global-genome (XPC-1) and transcr

270 rlying immunological mechanisms and revealed compensatory roles of neutrophils and B cells in present

271 Whether such learned compensatory saccades are optimal and generalize to more

272 h transient NMDAR inactivation also leads to compensatory scaling of synaptic AMPA receptors that enh

273 p mutant we isolated previously had acquired compensatory secondary mutations.

274 rtex of deaf individuals is reorganized to a compensatory sensory function during development.

275 dly affect therapy resistance by influencing compensatory signaling and expanding proliferation.

276 Thus, our results identify a compensatory signaling mechanism that prevents lineage-f

277 ITD+ cell lines showed that BMX is part of a compensatory signaling mechanism that promotes AML cell

278 treatment, because it is critical to impede compensatory signaling mechanisms that can engender drug

279 Compensatory signaling pathways in tumors confer resista

280 ical benefits, possibly due to activation of compensatory signaling pathways, which are frequently as

281 These changes appear compensatory, since mutant males but not females perform

282 Compensatory social behavior in nonhuman animals followi

283 mal models that indicate that distal tubular compensatory sodium reabsorption is a primary driver of

284 tion in natural communities are moderated by compensatory species dynamics, yet these processes are r

285 Here we studied unconstrained compensatory strategies under ecological conditions in o

286 s substitution quickly followed by a second, compensatory substitution.

287 pes of substitutions that will emerge (i.e., compensatory substitutions versus reversion of existing

288 , and explains multinucleotide mutations and compensatory substitutions without invoking positive sel

289 Here we report isolation of a compensatory suppressor mutation in the lower 50 kDa sub

290 redundancy, which provides them with robust compensatory survival mechanisms.

291 cogene-governed pathways or participating in compensatory transduction networks to strengthen tumor p

292 bute to community-level and population-level compensatory trends in seedling survival.

293 tion or tumorigenesis over 12 months, due to compensatory tumor barriers in p16-pRB and p19-p53-p21 a

294 of lipid-linked oligosaccharides (LLOs) and compensatory up-regulation of genes in the terpenoid bio

295 Ablation of Actbeta or Actgamma leads to compensatory up-regulation of the two other isoforms, wh

296 velopment, through a mechanism that includes compensatory upregulation of Lgr5.

297 e displayed incomplete dRTA characterized by compensatory upregulation of the Na(+)/HCO3(-) cotranspo

298 ant viruses, which includes the need for the compensatory V165I IN substitution, highlights a relativ

299 By contrast, potentiation of endogenous compensatory vasoactive peptides can act to enhance the

300 his apparent paradox can be explained by two compensatory water effects.