ライフサイエンスコーパス: competent

1 e of bacterial gastroenteritis, is naturally competent.

2 thus suggesting that the latter were fusion competent.

3 yrene, and this complex is not catalytically competent.

4 ient, rendering it soluble and translocation competent.

5 , it is not known which tau species are seed-competent.

6 rush border whenever the tissue is transport competent.

7 bon-style active zones were initially fusion competent.

8 s, and were fully replication- and infection-competent.

9 dissociated Gag molecules remained assembly competent.

10 SRI31277 reduced tumor burden in the immune competent 5TGM1 myeloma model.

11 myloid peptide (Abeta) by remodeling seeding-competent Abeta oligomers into off-pathway seeding-incom

12 rase activity by (i) bringing polymerization-competent actin monomers in proximity to growing filamen

13 and the di-domain linker form catalytically competent active sites and provide insight on the evolut

14 In contrast, replication-competent Ad (RC-Ad) vaccines are markedly more potent b

15 ity that a typical trainee would be rated as Competent after performing an average Core procedure on

16 a pre-organized ligand shell for kinetically competent and error-free photo-assembly of the Mn4CaO5-c

17 od and LNs for the production of replication-competent and infectious HIV-1, and for active and persi

18 , spleen, and gut, and contained replication-competent and infectious virus.

19 P2X7-competent and P2X7-deficient macrophages were isolated a

20 r, the preferential recognition of autophagy-competent and polyploid cells by the innate and cellular

21 Although Neisseria meningitidis is naturally competent and porB genetic mosaicism provides evidence f

22 ed by the regulatory domain is catalytically competent and that Thr(507) phosphorylation is not requi

23 The targeted PGCs were germline competent and were used to produce DDX4 null offspring.

24 g step that renders synaptic vesicles fusion-competent, and their genetic elimination causes a comple

25 sufficient to stimulate an increase in ADCC-competent antibodies, despite viral rebound in all subje

26 ion of MDSCs in comparison with functionally competent antigen-presenting cells.

27 dynamics of each subunit in a polymerization-competent antithrombin dimer.

28 n ApoE(-/-)Irf5(-/-) mice compared with IRF5-competent ApoE(-/-) mice.

29 at Golgi-localized K-Ras is not as signaling-competent as its PM-bound form.

30 d black African men reporting being sexually competent at sexual debut were lower (32.9% for black Ca

31 ParA dimer interface, stabilizing the ATPase-competent ATP sandwich dimer, ultimately driving ParA DN

32 catalytic system based on the generation of competent Au and Pd species by anionic ligand exchange.

33 Competent authorities are faced with the challenge to pr

34 National Reference Laboratory together with competent authorities conducted extended investigations

35 vation of DNA repair pathways or in a repair-competent background due to genotoxic stress from cellua

36 om the DNA discrimination described in other competent bacteria.

37 ent C57BL/6 and sampling-deficient/migration-competent BALB/c mice.

38 In particular, with time, thermogenic-competent beige adipocytes progressively gain a white ad

39 s essential for the formation of segregation-competent bivalents during meiosis I, and findings sugge

40 TgPyC) is dispensable not only in glycolysis-competent but also in glycolysis-deficient tachyzoites d

41 iator in LCR looping, we expressed a looping-competent but transcription-activation deficient form of

42 We also tested a metabolically competent, but avirulent, Salmonella enterica serovar Ty

43 h dampen anticancer immunity) from autophagy-competent, but not autophagy-deficient, mutant KRAS-indu

44 Using mating-competent C. albicans haploids, each carrying a differen

45 differ between sampling-competent/migration-competent C57BL/6 and sampling-deficient/migration-compe

46 reveals the conformation of a catalytically competent Cas9, which is prone for catalysis and whose e

47 solated complex has been shown to serve as a competent catalyst for the trans-hydroboration reaction.

48 dacyclic complexes containing NOx anions are competent catalysts for acetoxylation of 8-methylquinoli

49 Initially we confirmed that respiratory-competent cells can be produced following incubation of

50 assay to measure the function of the immune-competent cells in PD effluent from PD patients.

51 As the immune-competent cells of the brain, microglia play an increasi

52 l pathways impair peptidoglycan synthesis in competent cells.

53 increase chemotherapy-induced damage in BRCA-competent cells.

54 ceptor levels on target cells or eliminating competent chemokine receptor-binding sites on Env trimer

55 an." We suggest that for many healthy immune-competent children presenting with typical viral respira

56 ng blastocyst injection, generating germline-competent chimeras.

57 rabidopsis rbcs mutants expressing 'pyrenoid-competent' chimeric Arabidopsis SSUs containing the SSU

58 Metastasis-competent circulating tumour cells (CTCs) experience oxi

59 ify the source of infection in a replication-competent clone that unknowingly contaminated a safe exp

60 her applications in research, only the best, competent clones should be used.

61 nteractions that stabilize the catalytically competent closed conformation of the polymerase.

62 fA and RF2 help RF2 to adopt a catalytically competent conformation for peptide release.

63 s inability to support the substrate binding-competent conformation of EcMazF.

64 ubstrates is not dependent on the initiation-competent conformation of the APC/C.

65 ite becomes embraced to achieve its cleavage competent conformation.

66 pha holoenzyme in an extended and activation-competent conformation.

67 protein's C-terminal domain has a PG-binding-competent conformation.

68 s between a 'closed' and an 'open', bridging competent, conformation driven by environmental cues and

69 ease from chaperones, for preserving binding-competent conformations before insertion into the outer

70 a partial lifting of the "feed ban" and the competent control organisms are urged to develop suitabl

71 ase release) compared to that with the hypha-competent control.

72 ding amino acids and more complex amines are competent coupling partners.

73 outer ZN matrix and release of transfection competent CS/DNA NPs occurred in simulated intestinal co

74 and colleagues use a laminin polymerization-competent, designer chimeric BM protein in vivo to resto

75 ific deuterium uptake of this polymerization-competent dimer strongly supports a beta4A-beta5A beta-h

76 lical domain in establishing a catalytically competent dimeric cyclase conformation.

77 VP5*) and VP7, surround a transcriptionally competent, double-layer particle (DLP), which they deliv

78 s antigen-exposed, tolerance-prone RTEs into competent effector cells.

79 Patients perceived trauma team members as competent, efficient, and caring.

80 e two key stages for producing fertilization-competent eggs.

81 The hydroxide complex was found to be a competent electrocatalyst for O-O bond formation, a key

82 lso delays refolding of the remaining fusion-competent Env trimers.

83 nate from the posterior pre-primitive-streak competent epiblast by sequential upregulation of SOX17 a

84 t tRFs post-transcriptionally silence coding-competent ERVs, while 18 nt tRFs specifically interfere

85 6* formation in a kinetically and chemically competent fashion in the reaction of beta2 containing 2,

86 the spliceosome and stabilize a conformation competent for 3'-splice site docking, thereby promoting

87 have tested whether medulloblastomas must be competent for apoptosis to be sensitive to radiotherapy.

88 osphatidylserine and PIP2) to make PI3Kalpha competent for bilayer docking, as well as for subsequent

89 the HD-PTP open conformation is functionally competent for binding cellular protein partners.

90 ry complex generates the active trans-isomer competent for carbonyl bond activation by active-site re

91 ain multiple alpha satellite arrays that are competent for centromere assembly.

92 that the cut7Deltapkl1Delta spindle is fully competent for chromosome segregation independently of mo

93 his species is basic with a pKa of 24.3.2 is competent for concerted proton-electron transfer from TE

94 CD107a, produced IL2 and IFNgamma, and were competent for differentiation.

95 this complex, TnpA is in an activated state competent for DNA cleavage and strand transfer.

96 However, TREX1 mutants competent for DNA exonuclease activity are also linked t

97 d by XPB, XPD, p62, p52, p44, p34, and p8 is competent for DNA repair, while the CDK-activating kinas

98 s required for daughter centrioles to become competent for duplication, and for mother centrioles to

99 driven VLPs, provided that the F protein was competent for endocytic trafficking.

100 It is still unknown how follicles become competent for follicle rupture/ovulation.

101 length viral RNAs or surrogate gag-pol mRNAs competent for Gag synthesis to non-PM membranes or the a

102 ssembly in the procapsid (PC-portal) that is competent for high affinity binding to the large termina

103 motif of E6AP renders the conformation of E6 competent for interaction with p53 by structuring a p53-

104 rary to conventional notion, S-OPA1 is fully competent for maintaining mitochondrial energetics and c

105 umulation of assembly intermediates that are competent for maturation.

106 iting pathway are adenylated and, therefore, competent for post-editing A/U-tailing and translational

107 ted CRISPR-Cas systems implies that they are competent for pre-CRISPR RNA (precrRNA) processing yield

108 cient integration events, "young" proviruses competent for retrotransposition-found in many mammals,

109 ote initial enhancer formation, which is not competent for sustained activation.

110 A receptor binding-competent form of EDA1 was the main form of EDA but a mi

111 ntiviral strategies because it is the fusion-competent form of the protein and the primary target of

112 ntains amyloidogenic subunits in a secretion-competent form.

113 y targeting a proteolytically primed, fusion-competent GP intermediate (GPCL) generated in host cell

114 ify GISTs into two distinct clusters: an SDH-competent group and an SDH-deficient group.

115 Here we utilize chimeric mice with competent hematopoietic-driven immunity, to show that EB

116 nnate or adaptive immune responses in immune-competent, hemophilic mice.

117 s (IL-4 and IL-10) in the recipients of CD47-competent hepatocytes, mice receiving CD47-deficient hep

118 cells was detected in the recipients of CD47-competent hepatocytes, which was required for tolerance

119 cterize the whole-body burden of replication-competent HIV in individuals on effective antiretroviral

120 model to mimic the selection of replication-competent HIV-1 intersubtype recombination in dual or su

121 ed memory CD4(+) T cells bearing replication-competent HIV-1 provirus integrated into cellular DNA.

122 infection in vivo, we devised a replication-competent HIV-1 reporter virus that expresses a heterolo

123 CD4 cells latently infected with replication-competent HIV-1, compared with previous observations in

124 infection can cause lung injury in an immune competent host.

125 he cellular tropism of noroviruses in immune-competent hosts remains enigmatic.

126 esponse and were promptly rejected in immune competent hosts.

127 restrict HRV replication because replication-competent HRV antagonizes the type III IFN response at p

128 k HOXA expression compared with repopulation-competent human cord blood CD34(+) cells, indicating inc

129 PDX1 gene, which when combined with chimeric-competent human pluriopotent stem cells may serve as a s

130 effects of PK11195 on hCAR in metabolically competent human primary hepatocytes (HPH) and HepaRG cel

131 g protocol that combines a fully replication-competent IAV-WSN strain and a respiratory syncytial vir

132 wide array of genes, mainly in animals with competent IL-17RA signaling.

133 achinery in neutrophils required for a fully competent immune response to bacterial infection.

134 care of athletes should be knowledgeable and competent in ECG interpretation in athletes.

135 of the increasing demand for CV specialists competent in the care of CAHAP, the American College of

136 kLANA knock-in (KLKI) MHV68 was replication competent in vitro and in vivo but exhibited slower grow

137 All ILC subsets are functionally competent in vitro, and are sufficient to provide enhanc

138 Microbial colonisation promotes competent innate and acquired mucosal immune systems, ep

139 blocking probable formation of catalytically competent interactions with noncognate substrates and fo

140 A well-defined Pd(II)-peroxo complex is a competent intermediate that promotes substrate coordinat

141 er proteins or cofactors (with catalytically competent kinetics) plus hydroxylated 17alpha-hydroxyste

142 y reproducible assay to quantify replication-competent latent HIV in resting CD4(+) T cells, both inc

143 and rapidly quantify inducible, replication-competent latent HIV-1 from resting CD4(+) T cells is es

144 sed assay to quantify inducible, replication-competent latent HIV-1.

145 tive owing to the persistence of replication-competent, latent proviruses in long-lived resting T cel

146 We examined EMT-competent lung epithelial cells and lung fibroblasts fro

147 n of caspase 1 and interleukin-1beta in P2X7-competent macrophages.

148 he proper assembly and function of the decay-competent mammalian decapping complex suggests an additi

149 e less-phosphorylated IPs in a catalytically competent manner, suggesting that IP hydrolysis has a ro

150 nucleocapsid is the key to producing fusion-competent mature spikes on alphaviruses.

151 nistic details on the formation of signaling-competent MAVS filaments from inactive monomers.

152 s delineate melanoma formation from melanoma-competent MCSCs following extrinsic stimuli, and they su

153 cifically, melanomas originate from melanoma-competent MCSCs upon stimulation by UVB, which induces M

154 incorporation of a synthetic, catalytically competent metallocofactor into a protein scaffold to gen

155 ed smaller atherosclerotic lesions than P2X7-competent mice (0.162 cm(2)+/-0.023 [n=9], P2X7(-/-) low

156 ponsible for bacterial persistence in immune-competent mice are dispensable in mice with predisposing

157 We found that treatment of immune competent mice bearing orthotopic breast tumors with ant

158 mice developed persistent infection, immune-competent mice cleared the virus within 3 to 5 weeks.

159 we show that poliovirus infection in immune-competent mice requires adaptation to tissue-specific in

160 rculosis infection compared with fully IL-10-competent mice, indicating a major role for T cell-deriv

161 aradigms, however, warrant the use of immuno-competent mice, that more accurately capture the relevan

162 igation of dual-targeting concepts in immuno-competent mice, we now applied and optimized our method

163 ation of persistent B-cell aplasia in immune-competent mice.

164 not stimulate T-cell infiltration in immuno-competent mice.

165 e epithelium did not differ between sampling-competent/migration-competent C57BL/6 and sampling-defic

166 otect the heart by transplanting respiration-competent mitochondria to the injured region.

167 ing the contribution of T cells in an immune competent model.

168 e in vivo EMT and represent the first immune competent mouse model for distant hematogenous spread.

169 Further, this study provides a T cell competent mouse model for investigating ZIKV-specific T

170 ery, contributes to the generation of export-competent mRNPs and influences gene expression through i

171 accharomyces cerevisiae generation of export-competent mRNPs terminates the nuclear phase of the gene

172 y homodimerization forming monomeric priming-competent Munc13.

173 Many replication-competent mutants not yet observed in nature were identi

174 The bridging di-iron imido is a competent N-group transfer reagent to cyclic internal ol

175 re classified into 3 molecular subtypes: SDH-competent (n = 11), defined by detection of SDHB by IHC;

176 the capacity to rapidly elaborate an immune-competent niche that sustains protective immune cells en

177 nstruments, while as also providing a global competent/noncompetent decision for each performance.

178 Applying these standards, competent/noncompetent trainees could be discriminated i

179 Thus, replication-competent NYVAC-C-KC vectors acquired relevant immunolog

180 We sought to establish expansion-competent OE stem cell cultures to facilitate further st

181 ent oligomers that are isomeric with amyloid-competent oligomers in some cases.

182 f HD5 in infection and spread of replication-competent, oncolytic HAdV type 3 (HAdV3).

183 ng those of blastocysts from developmentally competent oocytes.

184 ound closed conformation or a transamidation-competent open conformation.

185 Streptococcus sanguinis, a naturally competent opportunistic human pathogen, is a Gram-positi

186 CD4 T cells containing inducible replication-competent or infectious virus, respectively.

187 Like many competent organisms, C. jejuni restricts the DNA that ca

188 elf-renewal of human tips as differentiation-competent organoids.

189 On E15.5, the fraction of competent oscillators increased dramatically correspondi

190 mice receiving CD47-deficient, but not CD47-competent, OVA(+) hepatocytes showed significantly enhan

191 In reactivity studies, 2 was shown to be a competent oxidant in an intermetal oxygen atom transfer,

192 A catalytically competent palladacyclic dimer intermediate has been iden

193 ivity to PLX4720 compared to the respiration-competent parental lines.

194 , and Toulouse (France), including 44 immune-competent patients with acute HEV infection, 18 HEV-expo

195 ute, community-acquired infections in immune competent patients, rather than to save lives.

196 the 'initiation' state into a catalytically competent pentameric state, is accompanied by substantia

197 nt age could be discriminatory and take many competent physicians out of practice and risk a physicia

198 nner that requires SUMOylated or SUMOylation-competent PML.

199 e that cell division arrest is programmed in competent pneumococcal cells to ensure that transformati

200 ause of the unstructured states of targeting-competent preproteins.

201 idative maturation to form the catalytically competent prFMN(iminium) species.

202 To assess whether the PMCA-competent prions residing at the maternal-fetal interfac

203 otein misfolding cyclic amplification (PMCA)-competent prions within the female reproductive tract an

204 tion and the labile character of the sensory-competent progenitors, which could have facilitated the

205 es instead with the CP in the ATP-hydrolysis-competent proteasome.

206 ar reaction from the monomer to the assembly-competent protomer, which then oligomerizes rapidly to a

207 nce in CD4+ T cells that contain replication-competent provirus, but exhibit little or no active vira

208 On reactivation of replication-competent provirus, HIV-1 envelope glycoproteins (Env) a

209 re likely to harbor full-length, replication-competent provirus.

210 oring immunologically silent but replication-competent proviruses - termed the latent reservoir.

211 against in vivo, and cells with replication competent proviruses expand and survive because only a s

212 e to the existence of latent but replication-competent proviruses residing primarily in a very small

213 (+) cells potentially containing replication-competent proviruses, along with evidence of continuing

214 of trace amounts of mutant proteins from NMD-competent PTC-containing constructs was not affected by

215 ) of PTC-containing mRNAs expressed from NMD-competent PTC-containing constructs were as stable as th

216 affected HSCs or bone marrow cells into Treg-competent recipients.

217 phase 1 trials of an attenuated, replication-competent, recombinant vesicular stomatitis virus (rVSV)

218 PD-L1, and fail to produce effective immuno-competent regulatory T cells (Tregs).

219 eloping chicken embryos, we used replication-competent retroviral RCAS vector system to generate tran

220 tective capacity of recombinant, replication-competent rhesus monkey rhadinovirus (RRV), a persisting

221 amma-TuSC oligomerization into MT nucleation-competent rings.

222 early evolution by addition of small folding-competent RNAs.

223 bsAbs for pre-clinical evaluation in immuno-competent rodents.

224 olds mTORC1 on the 3'UTRs of translationally-competent RP mRNAs to facilitate mTORC1-dependent induct

225 to a tetrameric complex that is required for competent rRNA processing.

226 cular phenotype and the generation of repair-competent SCs, which direct functional repair.

227 Here, we show that interferon signalling-competent SJL mice support chronic ZIKV infection.

228 A replication-competent species was evolved with the acquired mutation

229 could reprogram them to a "youthful" growth-competent state and promote regeneration of other types.

230 s ASC and brings ASC into an oligomerization-competent state by allowing Tyr146 phosphorylation to pa

231 The transition to the active DNA binding-competent state occurred highly cooperative and was conc

232 t Sox11 can reprogram adult RGCs to a growth-competent state, suggesting that different growth-promot

233 ch GRK structure is to being a catalytically competent state.

234 domain to a high-affinity GPIbalpha binding competent state.

235 cally slowed sampling of potentially folding-competent states, as compared with a random-coil polypep

236 cal, hepatic, and renal function, and immune-competent status (patients with HIV, immunosuppression,

237 acial expressions in response to emotionally-competent stimuli associated with different categories o

238 d in the L2 region converting caspase-6 to a competent substrate-binding state.

239 ontaining guaiacol and veratrole motifs were competent substrates for functionalization.

240 ctural information on complexes with folding-competent substrates remains lacking.

241 In addition, linear amides also prove to be competent substrates, and the phthaloyl-protected produc

242 of IN protomers supporting two catalytically competent subunits.

243 Furthermore, 1 is shown to be a competent synthetic tool for preparing O-labeled diols u

244 to efficiently replicate in interferon (IFN)-competent systems.

245 production of self-tolerant and functionally competent T cells.

246 fibrils constitute the major species of seed-competent Tau in the brains of transgenic mice.

247 It requires the uptake of seed-competent tau into cells, seeding of soluble tau in reci

248 ers from TgP301S tau mice and show that seed-competent tau species comprise small fibrils capable of

249 sected the molecular characteristics of seed-competent tau species from the TgP301S tau mouse model u

250 nintegrated OmpLA mutants remained insertion-competent, they were slowly degraded by the periplasmic

251 ions required Elk-1 to be phosphorylated and competent to activate transcription.

252 complexes are catalytically and kinetically competent to be intermediates in allylic substitutions o

253 ocytes matured in vitro tend to be much less competent to become fertilized, advance to the blastocys

254 However, while JunD is competent to bind DNA, the FosB bZIP domain must undergo

255 n (INCENP) during mitosis and that INCENP is competent to drive accumulation of the kinase to the cen

256 -natural cytokine receptor hetero-dimers are competent to elicit a signaling output.

257 leukemic transformation because they are not competent to express FLT3(ITD) target genes.

258 entially samples conformations that are more competent to FcgammaRIIIa binding, compared to the trunc

259 ion of 3-(trimethylsilyl)prop-2-yn-1-ols was competent to generate diarylated alpha,beta-unsaturated

260 downregulate FvTFL1 and to make these plants competent to induce flowering at low postvernalisation t

261 sue engraftment by human mast cells that are competent to mount specific IgE-mediated responses and d

262 ucture from cellulose I to cellulose II, was competent to prepare SREL as an ideal representative for

263 vitro, uS11 only when bound to Fap7 becomes competent to recruit eS26 through tertiary contacts foun

264 s required to make Xenopus pluripotent cells competent to respond to all cell fate inducers tested.

265 or in mid-larval neuroblasts, rendering them competent to respond to the systemic hormone ecdysone.

266 Moreover, Sse1sbd was fully competent to support Hsp90-dependent signaling through h

267 the germline to produce MII oocytes that are competent to sustain early zygotic development.

268 was azide-containing derivative 1j that was competent to undergo a strain-promoted azide-alkyne cycl

269 s toward smaller oligomeric species that are competent to undergo ERAD.

270 determined to be chemically and kinetically competent to undergo the proposed elementary steps of th

271 Prolinyl groups, which are catalytically competent toward asymmetric aldol reactions, were select

272 dance between technically and nontechnically competent trainees was identified (P < 0.001).

273 ins, alkynes, heterocycles, and epoxides are competent traps in the bromonium-induced cyclizations, l

274 Supplementation of isogenic c-Rel-competent Treg cells from prediabetic NOD mice reversed

275 This effect was only observed for autophagy-competent tumors, depended on the presence of T lymphocy

276 L-2 is necessary to render them functionally competent upon NKG2D engagement.

277 refully optimized method for making a branch-competent ureteric bud, a tissue fundamental to kidney d

278 -594 (mouse-prototype JX-594), a replication-competent vaccinia virus administered by intravenous inj

279 on, loss of Stx1 completely abolished fusion-competent vesicles and severely impaired vesicle docking

280 dent docking and evoked exocytosis of fusion-competent vesicles.

281 rVSV-ZEBOV is a recombinant, replication competent vesicular stomatitis virus-based candidate vac

282 or the efficient assembly of HBV replication-competent viral capsids.IMPORTANCE Hepatitis B virus (HB

283 otein, the CD4 T cells harboring translation-competent virus can be identified.

284 total and integrated HIV-1 DNA, replication-competent virus measurement by large cell input quantita

285 latent HIV-1 genomes that encode replication-competent virus persist in resting CD4(+) T cells.

286 f independent clonal isolates of replication-competent virus revealed that 57% had env sequences iden

287 The frequency of cells carrying replication-competent virus was less than 1 per 10(6) circulating CD

288 s after ART interruption, and no replication-competent virus was rescued from the tissue macrophages

289 as the increased safety of a non-replication-competent virus, which makes this approach attractive as

290 dy sensitivity in the context of replication-competent virus.

291 ently-infected cells that harbor replication competent virus.

292 y infected rCD4 cells containing replication-competent virus.

293 d DNA in human cells, as well as replication-competent-virus-producing cells, were measured to quanti

294 by the quantity of HIV-1 DNA and replication-competent-virus-producing cells.

295 of reactivation, suggesting that replication-competent viruses are less likely to be found among high

296 f striatal dopamine axonal sites with uptake-competent VMAT2 vesicles are capable of transmitter rele

297 xed ethnicity women reporting being sexually competent were lower (18.0% for black African and 35.3%

298 Virus in semen is replication-competent with no change in viral genome over time.

299 s a "flexibility window" to be catalytically competent, with both too low and too high mobility being

300 sed through targeted training for culturally competent, youth-friendly care, and intensive motivation