ライフサイエンスコーパス: competent

1 indicating that the viruses were replication competent.

2 ion of reprogrammed PSCs are developmentally competent.

3 9K) pre-synaptic complexes are recombination competent.

4 unnatural tyrosine residue are catalytically competent.

5 re shown to be catalytically and kinetically competent.

6 lymphoid organs confirmed to be replication competent.

7 deficits but remain viable and electrically competent.

8 s, and thus could potentially be replication-competent.

9 pen configuration that is nucleotide binding-competent.

10 zed, characterized, and proved catalytically competent.

11 ecific oxidation patterns, are rearrangement-competent.

12 This demonstrates a competent 24-hour molecular pacemaker in Bmal1 knockouts

13 conformational changes produce a translation-competent 80S complex.

14 he spatial organization of transcriptionally competent active rDNA chromatin at size scales well belo

15 equired for the formation of a catalytically competent active site.

16 The formed N-O-acetals are competent acylimine precursors.

17 were primed twice mucosally with replication-competent adenovirus type 5 host range mutant (Ad5hr)-si

18 1 (MAV-1) in mice to study oral replication-competent adenovirus-based vaccines.

19 te widely in the body.IMPORTANCE Replication-competent adenoviruses appear to be promising vectors fo

20 reducing the populations of membrane-binding competent alphaS oligomers but possibly also by shieldin

21 components, static metasurfaces are used as competent alternatives.

22 These data suggest that desmin forms seeding-competent amyloid that is toxic to myofibers.

23 atility of viral genomes and how replication-competent and -defective virus variants can provide mean

24 age of naturally occurring tail regeneration-competent and -incompetent developmental stages of Xenop

25 anced axon regeneration in both regeneration-competent and -incompetent sensory neurons in the periph

26 enic populations, all cells become naturally competent and bind exogenous DNA.

27 enylation site usage between DNA methylation-competent and DNA methylation-deficient cells.

28 multiple oxidative phosphorylation (OXPHOS)-competent and incompetent cancer cell pairs to demonstra

29 lations were highly enriched for replication-competent and intact provirus, transcribed HIV, and disp

30 g paternalistic advice are judged to be less competent and less helpful.

31 Memory, but not naive, T cells were competent and monocytes were required for CD3/CD28-media

32 ells were injected intravenously into immune-competent and NOD/SCID mice, and lung metastases were qu

33 ses of larvae that are a mixture of ribosome-competent and non-competent cells suggest a global regul

34 ategy aims to widen the use of PARPi in BRCA-competent and olaparib-resistant cancers, making fully s

35 ning bioenergetic homeostasis of both OXPHOS-competent and OXPHOS-defective cells, with Ca(2+) regula

36 bioenergetics in these cells, we used OXPHOS-competent and OXPHOS-defective cells.

37 ced SIRT1-dependent autophagy in both OXPHOS-competent and OXPHOS-defective cells.

38 during suppressive cART are translationally competent and produce the HIV-1 Gag and Nef proteins.

39 41 epitope, while the Y(cis)P is not binding competent and shows a higher aggregation propensity.

40 Immune-competent animal models for the hepatitis C virus (HCV)

41 tionally monocyte-derived cells (MCs) become competent antigen-presenting cells (APCs).

42 New transformation-competent Arabidopsis lines, with new plastid transforma

43 the historical unavailability of kinetically competent assays with physiologically relevant substrate

44 ensory inner hair cells (IHCs), which become competent at about the onset of hearing (P12).

45 The construct, NYVAC-KC, is a replication-competent, attenuated recombinant of the vaccinia virus

46 ing food fraud, the Centre together with the competent authorities and several EC services undertook

47 and the creation of expert networks with the competent authorities of the EU Member States.

48 Pfn1 ablation limited regeneration of growth-competent axons after sciatic nerve and spinal cord inju

49 its ability to be taken up and expressed by competent bacteria.

50 electrospun fibers that are biomechanically competent, biocompatible, and capable of dual drug relea

51 or the first time, a recombinant replication-competent bireporter IAV (BIRFLU) that stably expresses

52 g, boosted SARS-CoV-2 replication in the IFN-competent Calu-3 cells.

53 d end-of-life issues; 3) need for culturally competent care in surgery to navigate cultural differenc

54 ess to medical professionals who can provide competent care.

55 5' end enables the application of a nuclease competent Cas9 protein for transcriptional modulation of

56 ric product formation, the complex was not a competent catalyst for beta-lactam formation.

57 coordinated iron(0) complex, which is also a competent catalyst for hydromagnesiation.

58 These Ni(II) complexes serve as competent catalysts for the C-H functionalization of ami

59 demonstrated that nanovessels can be highly competent catalysts providing high rate accelerations an

60 Co-expression competent cells express graded levels of S- and M-opsins

61 table switch between non-active and transfer competent cells have long remained enigmatic.

62 tween cells leads to the elimination of less competent cells in the presence of more competent neighb

63 Whereas autophagic flux in OXPHOS-competent cells promoted cell survival, it was impaired

64 are a mixture of ribosome-competent and non-competent cells suggest a global regulatory mechanism in

65 ) and DprA stably co-localize at one pole in competent cells, with sigma(X) physically conveying DprA

66 effectively both as viable and biologically competent cells.

67 e conformations, including the catalytically competent closed state independent of the UBA domain.

68 mprovement programs; 2) effective culturally competent communication and team-based care; 3) improvin

69 confinement of end processing to a ligation-competent complex ensures that DNA ends undergo ligation

70 h subsequently matures into a 70S elongation-competent complex.

71 ession, and viral infection under interferon-competent conditions.

72 We reveal an NTS-cleavage-competent conformation following the HNH domain conforma

73 tails about how NMT1 reaches a catalytically competent conformation in which the reactive groups are

74 paradigm of conformation selection, binding-competent conformations of BPTI and trypsin are already

75 s, monomeric species first adopt aggregation-competent conformations.

76 ination-based repair (HR-) but not their HR+ competent counterparts.

77 , and bicyclic alkenes were also found to be competent coupling partners.

78 ruited by gRNA aptamer binding to a nuclease competent CRISPR complex containing truncated gRNAs.

79 emergence of heterogeneous and functionally competent cross-reactive and induced memory CD8(+) T cel

80 Competent D39 bacteria propagated the competence signal

81 ble to restore glucose homeostasis in immune-competent diabetic mice for 50 days.

82 dimethylsilyloxy)pyrroles are established as competent dienes for the synthesis of para-iminoquinones

83 ucture of a ternary complex of catalytically competent DNMT3A2, the catalytically inactive accessory

84 omains in the interior and transcriptionally competent domains located at the periphery.

85 n-functional state unable to form a cleavage-competent effector complex.

86 ganic molecules have been shown to behave as competent electron-transfer catalysts in photoredox reac

87 w beta-catenin signaling compared to barrier-competent endothelial cells, and (2) elevating beta-cate

88 Since the discovery of functionally competent, energy-consuming brown adipose tissue (BAT) i

89 (NK) cells and other innate lymphoid cells, competent enhancers are primed during lineage acquisitio

90 intestinal T(H)17 responses, even in a c-Maf-competent environment.

91 onstrates that human BCO2 is a catalytically competent enzyme.

92 th from odontodes, it has been proposed that competent epithelium spread into the oropharyngeal cavit

93 ision between S-opsin only and co-expression competent fates.

94 T cells in tonsils are fully responsive and competent for antigen-induced cytokine production in RAT

95 avoidance of CO(2), nhr-6 mutants are fully competent for attraction.

96 pes pericentromeres into a structure that is competent for chromosome segregation.

97 s Ae. malayensis population was overall less competent for DENV and YFV than an urban population of A

98 ICEKp2 was competent for excision, but self-mobilisation to recipie

99 stem cells into oocyte-like cells that were competent for fertilization and subsequent cleavage.

100 al screening of 47 species revealed 60% were competent for intracellular replication in THP-1 cells,

101 nger promotes assembly of a NucC homohexamer competent for non-specific double-strand DNA cleavage.

102 of a subset of cortical astrocytes that are competent for regulating dopamine (DA) homeostasis durin

103 erfering particle of VSV (DI-T) that is only competent for RNA replication requires significantly hig

104 loop formation and dictates access to states competent for stable binding and cleavage.

105 This superoxo complex is competent for stoichiometric oxidation chemistry with al

106 p was recently characterized and shown to be competent for substrate radical generation, presumably v

107 complex and then, an engaged complex that is competent for substrate unfolding.

108 latform to assemble pre-initiation complexes competent for transcription.

109 It is naturally competent for transformation-that is, it takes up DNA fr

110 express truncated hRpn13 (trRpn13), which is competent for UCHL5 binding but defective for proteasome

111 ic protein absorbed at 448 nm (catalytically competent form), whereas the monomeric form absorbed at

112 a switch to a ribosome depleted replication-competent form.

113 gamma-TuSC protein GCP3, in an "interaction-competent" form within the gamma-TuSC.

114 crose gradient centrifugation, the most seed-competent fractions from PD and MSA brains are those tha

115 altricial rodents, OHCs become functionally competent from around postnatal day 7 (P7), before the p

116 This procedure can be accomplished by a competent graduate student or technician with prior expe

117 The power of the catalytically competent group 1 HDM protease allergen component is dem

118 research; and growing a diverse, culturally competent health and healthcare workforce prepared to me

119 th TCDD and injected subcutaneously with AHR-competent Hepa1-GFP hepatoma cells or AHR-deficient LLC

120 mination of host cells harboring replication-competent HIV (SECH), which includes viral reactivation,

121 A loads as well as the levels of replication-competent HIV in CD4(+) T cells).

122 to measure and characterise the replication-competent HIV-1 reservoir, which constitutes the barrier

123 atently infected cells harboring replication competent HIV.

124 cleaved substrate bound to the catalytically competent HNH active site.

125 Ni/NiO interfacial sites was developed as a competent HOR electrocatalyst in alkaline media.

126 tes and monitoring the abundance of dominant competent hosts.

127 7 system in mice and establishes a secretion-competent human IL-27alpha that signals on its own and c

128 ComGC solution structures from two naturally competent human pathogens, Streptococcus sanguinis (ComG

129 lopropenium-based fluorophore functions as a competent imaging agent for DNA visualization and nuclea

130 While a competent immune system helps prevent clinically detecta

131 o MtNifB, holo MtNifB is fully assembled and competent in cofactor biosynthesis.

132 d NK cell engagers with a human IgG1 Fc part competent in Fc receptor binding resulted in an almost 1

133 4-dependent calcium signaling but were fully competent in recruiting beta-arrestin-1 and -2.

134 n aryl electrophiles only aryl triflates are competent in these couplings whereas aryl iodides and br

135 Physicians need to become competent in understanding the potential risks and benef

136 , but was defective in producing replication-competent initiation complexes.

137 lecular circadian clock in the regulation of competent insulin-producing beta cells.

138 ociate with an encapsulin nanocage to form a competent iron store that is capable of holding signific

139 ndent tumor formation originating from tumor-competent Krt5(+)/Krt15(+) foregut basal progenitor cell

140 somal particles are converted to translation-competent large ribosomal subunits.

141 and efficient quantification of replication-competent latent reservoirs (LR).

142 response was modulated using a metabolically competent liver module that converted terfenadine to fex

143 cleotides on the assembly of a catalytically competent maturation complex on viral DNA, their effect

144 to facilitate the formation of mature export-competent messenger ribonucleoprotein particles and to p

145 We showed that the seeding-competent mHTT species in HD CSF are significantly eleva

146 -1(KO) cells failed to form tumors in immune-competent mice but displayed robust tumor growth compara

147 el using vaccine-challenge studies in immune-competent mice with native expression of mouse ACE2.

148 In prohibitin-competent mice, elongation of liver mitochondria by expr

149 utic responses in E.G-7 tumor-bearing immune-competent mice, in which they were divided by their tumo

150 In contrast, in NK cell-competent mice, neutrophils facilitate metastatic coloni

151 ly occurs in the murine retina from Ca(v)2.3 competent mice, supporting the ideas derived from previo

152 e mice and in murine breast cancer in immune-competent mice.

153 .3-deficient mice, but prominent in Ca(v)2.3-competent mice.

154 ent cell-mediated immune rejection in immune competent mice.

155 on compared with the cells isolated from A20-competent mice.

156 mmune-deficient nude mice, but not in immune-competent mice.

157 e provide a direct example of a functionally competent misfolded state.

158 r transmission via bridge vectors, which are competent mosquitoes feeding on both humans and wild ani

159 sue culture assays, as well as a replication-competent mouse ACE2-adapted SARS-CoV-2 in BALB/c mice a

160 In an immune-competent mouse model of breast cancer, MLK3 inhibitor i

161 and reduces anti-tumor efficacy in an immune-competent mouse model.

162 antagonist-treated melanoma and NSCLC immune-competent mouse models.

163 gation-prone region additively contribute to competent mRNA export and stress granule formation, both

164 Therefore, we utilized immune-competent murine tumor models to investigate whether can

165 less competent cells in the presence of more competent neighbors via cell competition (CC).

166 t by templating the formation of an assembly-competent nucleation seed, but we find an unanticipated

167 ds, thiols and sulfonamides were found to be competent nucleophiles, providing ready access to alpha-

168 preoperative MRI such that the features are competent of predicting survival time.

169 ail to differentiate into mature myelination-competent oligodendrocytes, reminiscent of what is obser

170 , Use of mobility aid, Fall history, and Not competent on admission) were strongly associated with po

171 unspliced forms of HIV-RNA transcripts with competent open reading frames (ORFs), and can be found i

172 plets were perfused with different transport-competent or -incompetent cargo complexes, and then the

173 f any, replicative capacity in either immune-competent or immunodeficient mice, indicating a critical

174 fering affinities that are either complement competent or silenced.

175 upport the use of MAV-1 to study replication-competent oral adenovirus-based vaccines but also highli

176 Heart regeneration in regeneration-competent organisms can be accomplished through the remo

177 Interestingly, expression of the replication-competent Orsay virus RNA1 segment alone is sufficient t

178 ules were implanted subcutaneously in immune competent ovariectomized C57BL/6 mice for a period of 60

179 oxidant in oxidation reactions, it becomes a competent oxidant in oxygen atom transfer reactions, suc

180 alpha4beta7+ emigration- and mucosal-homing competent phenotype, while this was restricted to type A

181 Our goal was to generate competent photoreactive receptors that can be cross-link

182 required, and 4) suggest that the absence of competent platelets causes changes in the vessel wall it

183 ibility is abrogated by transfusion of HYAL2-competent platelets.

184 h Cpn60 captures and then releases insertion-competent Plsp1, whereas cpSecA1 recognizes free Plsp1 f

185 defence of staff's professional identity as competent practitioners; and defence of staff as having

186 TM) prevented the formation of any signaling-competent PreBCR complexes that may arise as a result of

187 ginally described by Schrauzer in 1962, is a competent precatalyst for a variety of nickel-catalyzed

188 Accurate and reproducible immune competent preclinical models are key to understanding me

189 en complex [(P(3) (B) )Co(H(2) )](1-) , is a competent precursor for hydride transfer to BEt(3) , est

190 loradical, (P(3) (B) )Co(H(2) ), serves as a competent precursor for hydrogen atom transfer to (t) Bu

191 factors, needed to assemble a transcription-competent preinitiation complex at the promoter.

192 rization and propensity to adopt non-binding competent proline conformers provides novel insight into

193 in remodeling and formation of transcription-competent promoters.

194 res chaperone assistance to direct insertion-competent proteins to integration pathways.

195 ) T cells that harbor latent but replication-competent provirus.

196 l pool of CD4+ T cells harboring replication-competent provirus.

197 tive of a cell clone harboring a replication-competent provirus.

198 arches have failed to reveal any replication-competent proviruses in humans.

199 gle HIV-infected cells harboring translation-competent proviruses in longitudinal samples from eight

200 t low catalyst concentration is obtained and competent rates in dilute conditions are maintained.

201 ew or metastable complex oxides, kinetically competent reactions with lower initial energy barriers m

202 e to the Schlenk equilibrium are found to be competent reagents for the nucleophilic pathway.

203 A replication-competent, recombinant strain of rhesus monkey rhadinovi

204 ithin social groups by making them seem more competent regardless of objective ability, so this bias

205 icant and sustained increase of functionally competent regulatory T (Treg) cells, whereas Th1 and Th1

206 where tested, sufficient drug release and a competent release profile.

207 uit, including monocyte differentiation into competent repairing AAMs, as well as group-2 innate lymp

208 of T cell escape variants in the replication-competent reservoir of 25 persons living with HIV-1 (PLW

209 pus alecto), which is the first reproduction-competent retrovirus found in bats.

210 indings suggest that testing for replication-competent retroviruses, a routine safety test for transd

211 cytin 1 and essentially acted as replication-competent retroviruses.

212 rescued to replenish the pool of translation-competent ribosomal subunits.

213 ee synthesis and assembly of translationally competent ribosomes with ribosome display to develop a f

214 ld, suggesting that EZH2 promotes a cleavage-competent RNA conformation.

215 It potently neutralized replication-competent SARS-CoV-2 but not SARS-CoV, as measured by tw

216 predictive clinical validity with predefined competent scores of 3 and 5 respectively.

217 Isonitriles, being competent sigma-donors, show a strong aptitude to form t

218 e activation and recruitment of osteogenesis-competent skeletal stem and progenitor cells (SSPCs).

219 R-17-92 families that make AGO3 an extremely competent slicer, increasing target cleavage up to ~82-f

220 exchange with a minor population of amyloid-competent species to induce fibrillogenesis.

221 are hypothesized to be the earliest seeding-competent species, M204-scFv may have potential as an ea

222 ng-deficient mice immunized with replication-competent sporozoites exhibit superior protection agains

223 ant for stabilizing the substrate-engagement-competent state and coordinating the conformational swit

224 The competent state began at approximately 20 h postinfectio

225 from a heterotrophic to a photosynthetically competent state during early seedling development.

226 ia-derived sepsis but failed to turn off the competent state in mice.

227 niversally reported short transient burst of competent state in vitro, the naturally developed compet

228 ormational pathway leading to the nucleation-competent state is unclear due to lack of high-resolutio

229 on reactivation by stabilizing the recycling-competent state of inactive ribosomes.

230 tent state in vitro, the naturally developed competent state was prolonged and persistent during pneu

231 t CDKA1 may promote a switch into a division-competent state, and E2F/Dp1 may promote maintenance of

232 itching an innocuous protein into an amyloid-competent state, rationalizing the localization of amylo

233 nformation is shifted toward an ACE2 binding-competent state, which is modeled to be on pathway for v

234 s, thereby controlling the duration of a DSB-competent state.

235 rellin production to condition a replication competent state.

236 regulates the exit of pneumococcus from the competent state.

237 for stabilizing the complex in a hydrolysis-competent state.

238 h DNA ends are closely aligned in a ligation-competent state.

239 ssociation, leading in turn to loss of a DSB competent state.

240 ng shifts the equilibrium toward the binding-competent states and decreases the mobility of the DNA-b

241 ibrium between an open state and DNA-binding competent states regardless of nickel binding, but a hig

242 ordered free energy ground state to assembly-competent states.

243 n among various RNA silencing-deficient and -competent strains showed clearly that the virus was unaf

244 he catalytic phosphorylation domain toward a competent structure.

245 tu generated radical species are shown to be competent substrates in reactions with oxygen-based radi

246 e assembling particles from kinetic traps to competent subunits during the 50S ribosome assembly proc

247 active zone membrane and formation of fusion-competent synaptic vesicles near voltage-gated Ca(2+) ch

248 particles (VLPs) from human cells to form a competent system for BSL-2 studies of SARS-CoV-2.

249 s), preventing FasL-induced apoptosis in Fas-competent T cells.

250 ge for tail regeneration in the regeneration-competent tadpoles.

251 We generated the first replication competent tagged reporter birnaviruses, infectious bursa

252 rylated species of soluble, oligomeric, seed-competent tau.

253 constitutively replaced from a proliferation-competent Tcf1-expressing progenitor population.

254 small hosts will be disproportionately more competent than large ones, an effect amplified by the hi

255 and Lyme disease, large hosts should be more competent than small ones, but their lower abundance cou

256 icher' clothes was judged significantly more competent than with 'poorer' clothes.

257 1 liquid-phase scaffold, and find that it is competent to bind and incorporate downstream active-zone

258 ased pool of non-nucleoid bound ParA that is competent to bind parOP and repress transcription.

259 ions that commercially available La(NTMS) is competent to catalyze, further underscoring the value an

260 ying a wide range of dysfunction, from fully competent to completely incompetent.

261 ons reveal that, while embryos are initially competent to express Sox2 as early as the four-cell stag

262 The structure of the lever in each head is competent to generate force upon activation.

263 d EAA and Glu in the second step medium were competent to implant and develop into fetuses at a simil

264 Remarkably, TbtD is competent to perform an intermolecular cyclization in ad

265 Complex 2 is kinetically and catalytically competent to perform the epoxidation of olefins with hig

266 PAR proteins are initially not competent to polarize but gradually acquire this ability

267 tricted Did2-Ist1 co-polymer that we show is competent to promote fission when bound on the inside of

268 ), is surrounded by transit amplifying cells competent to respond to auxin hormone maxima by giving r

269 tly, while cells pre-treated with HGF remain competent to respond to further HGF stimulation, cells p

270 ddressed this issue by using HBV replication-competent transgenic mice that are depleted of circulati

271 he feasibility of EVR to expand functionally competent Treg cells for their clinical use.

272 We show that competent V. cholerae acquire DNA fragments with a lengt

273 VSV-SARS-CoV-2 as an attenuated, replication-competent vaccine against SARS-CoV-2.

274 at oral immunization with such a replication-competent vaccine is associated with the systemic spread

275 ectedly, we found that such oral replication-competent vaccine systemically spread all over the body.

276 Here, we show that Lu. longipalpis is a competent vector of L. major parasites, being able to ac

277 Regeneration-competent vertebrates are considered to suppress inflamm

278 All synapses require fusion-competent vesicles and coordinated Ca(2+)-secretion coup

279 Y113K mutations reduced the number of fusion-competent vesicles and reduced the rates of release of c

280 Previously, we developed a replication-competent vesicular stomatitis virus (VSV) expressing a

281 A replication-competent vesicular stomatitis virus vaccine expressing

282 f cells harboring integrated and replication-competent viral genomes.

283 ers'), despite the presence of a replication-competent viral reservoir(1).

284 infection is the persistence of replication-competent viral reservoirs during antiretroviral therapy

285 bone resulted in the recovery of replication-competent virions with low susceptibility to the inhibit

286 modification in the assembly of replication-competent viroplasms.

287 associated SIV DNA, SIV RNA, and replication-competent virus comparable to those in PB.

288 Plasma virus matched replication-competent virus cultured from CD4+ T cells.

289 for 30 months with no detectable replication-competent virus in blood, CSF, intestinal tissue, or lym

290 rmed with sensitive methods, but replication-competent virus is not detected.

291 ntly infected cells that contain replication-competent virus(1-4).

292 ase of an insufficient amount of replication-competent virus.

293 f infected CD4+ T cells carrying replication-competent virus.

294 (+) T-cells) without evidence of replication-competent viruses (<0.025 IUPM), consistent with high le

295 are unable to encode intact and replication-competent viruses, they have long been thought of as bio

296 their distance from warm vs. cold, and even competent vs. incompetent, words (reflecting specific be

297 Additionally, replication-competent VSV-eGFP-SARS-CoV-2 provides a tool for testin

298 atitis virus (VSV), as well as a replication-competent VSV/SARS-CoV-2 chimeric virus.

299 erative contexts: we prefer partners who are competent, wealthy and generous, and those who abide by

300 , this indicates that the modified sensor is competent with that reported earlier.